SIMILAR PATTERNS OF AMINO ACIDS FOR 5W7B_B_PA1B204_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bg6 | N-(1-D-CARBOXYLETHYL)-L-NORVALINEDEHYDROGENASE (Arthrobactersp. 1C) |
PF02317(Octopine_DH)PF02558(ApbA) | 3 | GLY A 13ASN A 14ARG A 292 | None | 0.67A | 5w7bD-1bg6A:3.3 | 5w7bD-1bg6A:11.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dys | ENDOGLUCANASE (Humicolainsolens) |
PF01341(Glyco_hydro_6) | 3 | GLY A 185ASN A 183ARG A 276 | None | 0.47A | 5w7bD-1dysA:3.6 | 5w7bD-1dysA:12.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fxz | GLYCININ G1 (Glycine max) |
PF00190(Cupin_1) | 3 | GLY A 199ASN A 168ARG A 62 | None | 0.79A | 5w7bD-1fxzA:undetectable | 5w7bD-1fxzA:11.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1icf | PROTEIN (CATHEPSINL: HEAVY CHAIN)PROTEIN (INVARIANTCHAIN) (Homo sapiens) |
PF00086(Thyroglobulin_1)PF00112(Peptidase_C1) | 3 | GLY A 20ASN A 18ARG I 250 | None | 0.70A | 5w7bD-1icfA:undetectable | 5w7bD-1icfA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcz | BETA-METHYLASPARTASE (Clostridiumtetanomorphum) |
PF05034(MAAL_N)PF07476(MAAL_C) | 3 | GLY A 337ASN A 340ARG A 125 | None | 0.78A | 5w7bD-1kczA:undetectable | 5w7bD-1kczA:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kk0 | EIF2GAMMA (Pyrococcusabyssi) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF09173(eIF2_C) | 3 | GLY A 289ASN A 12ARG A 203 | None | 0.74A | 5w7bD-1kk0A:4.2 | 5w7bD-1kk0A:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kv9 | TYPE IIQUINOHEMOPROTEINALCOHOLDEHYDROGENASE (Pseudomonasputida) |
PF13360(PQQ_2)PF13442(Cytochrome_CBB3) | 3 | GLY A 531ASN A 535ARG A 609 | None | 0.65A | 5w7bD-1kv9A:undetectable | 5w7bD-1kv9A:8.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kv9 | TYPE IIQUINOHEMOPROTEINALCOHOLDEHYDROGENASE (Pseudomonasputida) |
PF13360(PQQ_2)PF13442(Cytochrome_CBB3) | 3 | GLY A 602ASN A 535ARG A 609 | None | 0.72A | 5w7bD-1kv9A:undetectable | 5w7bD-1kv9A:8.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpl | HYPOTHETICAL 25.4KDA PROTEIN F53F4.3IN CHROMOSOME V (Caenorhabditiselegans) |
PF01302(CAP_GLY) | 3 | GLY A 208ASN A 191ARG A 199 | None | 0.78A | 5w7bD-1lplA:undetectable | 5w7bD-1lplA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n21 | (+)-BORNYLDIPHOSPHATE SYNTHASE (Salviaofficinalis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 3 | GLY A 391ASN A 394ARG A 303 | None | 0.70A | 5w7bD-1n21A:undetectable | 5w7bD-1n21A:8.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n7r | HYALURONIDASE (Streptococcuspneumoniae) |
PF02278(Lyase_8)PF02884(Lyase_8_C)PF08124(Lyase_8_N) | 3 | GLY A 633ASN A 575ARG A 627 | None | 0.76A | 5w7bD-1n7rA:undetectable | 5w7bD-1n7rA:8.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1op2 | VENOM SERINEPROTEINASE (Deinagkistrodonacutus) |
PF00089(Trypsin) | 3 | GLY A 19ASN A 20ARG A 137 | None | 0.75A | 5w7bD-1op2A:undetectable | 5w7bD-1op2A:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5a | EP-CADHERIN (Mus musculus) |
PF00028(Cadherin) | 3 | GLY A 144ASN A 138ARG A 68 | CA A 905 ( 4.7A)NoneNone | 0.16A | 5w7bD-1q5aA:undetectable | 5w7bD-1q5aA:6.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qyc | PHENYLCOUMARANBENZYLIC ETHERREDUCTASE PT1 (Pinus taeda) |
PF05368(NmrA) | 3 | GLY A 274ASN A 278ARG A 216 | None | 0.78A | 5w7bD-1qycA:4.5 | 5w7bD-1qycA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rwr | FILAMENTOUSHEMAGGLUTININ (Bordetellapertussis) |
PF05860(Haemagg_act) | 3 | GLY A 90ASN A 43ARG A 87 | None | 0.65A | 5w7bD-1rwrA:undetectable | 5w7bD-1rwrA:11.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ryy | ALPHA-AMINO ACIDESTER HYDROLASE (Acetobacterpasteurianus) |
PF02129(Peptidase_S15)PF08530(PepX_C) | 3 | GLY A 377ASN A 376ARG A 394 | None | 0.75A | 5w7bD-1ryyA:2.6 | 5w7bD-1ryyA:7.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s0u | TRANSLATIONINITIATION FACTOR 2GAMMA SUBUNIT (Methanocaldococcusjannaschii) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF09173(eIF2_C) | 3 | GLY A 316ASN A 39ARG A 230 | None | 0.59A | 5w7bD-1s0uA:3.4 | 5w7bD-1s0uA:11.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sqg | SUN PROTEIN (Escherichiacoli) |
PF01029(NusB)PF01189(Methyltr_RsmB-F) | 3 | GLY A 258ASN A 289ARG A 177 | None | 0.62A | 5w7bD-1sqgA:2.7 | 5w7bD-1sqgA:11.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5c | CHITOSANASE (Bacillus sp.(in: Bacteria)) |
PF01270(Glyco_hydro_8) | 3 | GLY A 218ASN A 160ARG A 153 | None | 0.75A | 5w7bD-1v5cA:undetectable | 5w7bD-1v5cA:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a4k | 3-OXOACYL-[ACYLCARRIER PROTEIN]REDUCTASE (Thermusthermophilus) |
PF13561(adh_short_C2) | 3 | GLY A 89ASN A 111ARG A 38 | NoneUNX A 276 (-3.8A)None | 0.66A | 5w7bD-2a4kA:5.7 | 5w7bD-2a4kA:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e3i | RESTIN (Homo sapiens) |
PF01302(CAP_GLY) | 3 | GLY A 116ASN A 99ARG A 107 | None | 0.74A | 5w7bD-2e3iA:undetectable | 5w7bD-2e3iA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hnh | DNA POLYMERASE IIIALPHA SUBUNIT (Escherichiacoli) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 3 | GLY A 703ASN A 393ARG A 709 | None | 0.66A | 5w7bD-2hnhA:undetectable | 5w7bD-2hnhA:6.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpi | DNA POLYMERASE IIIALPHA SUBUNIT (Thermusaquaticus) |
PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 3 | GLY A 760ASN A 455ARG A 766 | None | 0.67A | 5w7bD-2hpiA:undetectable | 5w7bD-2hpiA:5.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o04 | PECTATE LYASE (Bacillussubtilis) |
PF00544(Pec_lyase_C) | 3 | GLY A 142ASN A 65ARG A 206 | None | 0.68A | 5w7bD-2o04A:undetectable | 5w7bD-2o04A:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oze | ORF DELTA' (Streptococcuspyogenes) |
PF13614(AAA_31) | 3 | GLY A 99ASN A 102ARG A 93 | None | 0.68A | 5w7bD-2ozeA:4.0 | 5w7bD-2ozeA:14.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pgg | RNA-DIRECTED RNAPOLYMERASE (Infectiousbursal diseasevirus) |
PF04197(Birna_RdRp) | 3 | GLY A 730ASN A 727ARG A 439 | None | 0.74A | 5w7bD-2pggA:undetectable | 5w7bD-2pggA:6.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q3r | 12-OXOPHYTODIENOATEREDUCTASE 1 (Arabidopsisthaliana) |
PF00724(Oxidored_FMN) | 3 | GLY A 206ASN A 199ARG A 152 | None | 0.78A | 5w7bD-2q3rA:undetectable | 5w7bD-2q3rA:11.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qkb | RIBONUCLEASE H1 (Homo sapiens) |
PF00075(RNase_H) | 3 | GLY A 167ASN A 171ARG A 275 | None | 0.71A | 5w7bD-2qkbA:undetectable | 5w7bD-2qkbA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgh | ALPHA-GLYCEROPHOSPHATE OXIDASE (Streptococcussp.) |
PF01266(DAO)PF16901(DAO_C) | 3 | GLY A 468ASN A 507ARG A 175 | None | 0.69A | 5w7bD-2rghA:undetectable | 5w7bD-2rghA:8.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2v26 | MYOSIN VI (Sus scrofa) |
PF00063(Myosin_head) | 3 | GLY A 459ASN A 477ARG A 667 | VO4 A1791 (-3.3A)EDO A1793 ( 4.6A)None | 0.58A | 5w7bD-2v26A:undetectable | 5w7bD-2v26A:7.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk4 | PYRUVATEDECARBOXYLASE (Kluyveromyceslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 3 | GLY A 120ASN A 119ARG A 127 | None | 0.73A | 5w7bD-2vk4A:undetectable | 5w7bD-2vk4A:9.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 3 | GLY A 240ASN A 291ARG A 170 | None | 0.71A | 5w7bD-2vsaA:undetectable | 5w7bD-2vsaA:6.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5f | ENDO-1,4-BETA-XYLANASE Y (Ruminiclostridiumthermocellum) |
PF00331(Glyco_hydro_10)PF02018(CBM_4_9) | 3 | GLY A 297ASN A 292ARG A 308 | None | 0.70A | 5w7bD-2w5fA:3.9 | 5w7bD-2w5fA:11.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wlv | GAG POLYPROTEIN (Humanimmunodeficiencyvirus 2) |
PF00607(Gag_p24) | 3 | GLY B 104ASN B 52ARG B 69 | None | 0.66A | 5w7bD-2wlvB:undetectable | 5w7bD-2wlvB:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aib | GLUCOSYLTRANSFERASE-SI (Streptococcusmutans) |
PF02324(Glyco_hydro_70) | 3 | GLY A1009ASN A 451ARG A 921 | None | 0.75A | 5w7bD-3aibA:undetectable | 5w7bD-3aibA:7.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3efm | FERRIC ALCALIGINSIDEROPHORE RECEPTOR (Bordetellapertussis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | GLY A 118ASN A 116ARG A 310 | None | 0.71A | 5w7bD-3efmA:undetectable | 5w7bD-3efmA:9.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3faw | RETICULOCYTE BINDINGPROTEIN (Streptococcusagalactiae) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 3 | GLY A 481ASN A 479ARG A 781 | None | 0.71A | 5w7bD-3fawA:undetectable | 5w7bD-3fawA:7.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3feh | CENTAURIN-ALPHA-1 (Homo sapiens) |
PF00169(PH)PF01412(ArfGap) | 3 | GLY A 77ASN A 18ARG A 82 | None | 0.78A | 5w7bD-3fehA:undetectable | 5w7bD-3fehA:12.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fle | SE_1780 PROTEIN (Staphylococcusepidermidis) |
PF06028(DUF915) | 3 | GLY A 178ASN A 183ARG A 199 | None | 0.75A | 5w7bD-3fleA:undetectable | 5w7bD-3fleA:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6r | DIHYDROOROTATEDEHYDROGENASEHOMOLOG,MITOCHONDRIAL (Plasmodiumfalciparum) |
PF01180(DHO_dh) | 3 | GLY A 231ASN A 289ARG A 296 | None | 0.75A | 5w7bD-3i6rA:undetectable | 5w7bD-3i6rA:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3idv | PROTEINDISULFIDE-ISOMERASEA4 (Homo sapiens) |
PF00085(Thioredoxin) | 3 | GLY A 261ASN A 192ARG A 246 | None | 0.76A | 5w7bD-3idvA:undetectable | 5w7bD-3idvA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6c | SERINE RACEMASE (Rattusnorvegicus) |
PF00291(PALP) | 3 | GLY A 186ASN A 154ARG A 135 | PLP A 350 (-3.6A)PLP A 350 (-4.3A)MLI A 341 (-3.2A) | 0.77A | 5w7bD-3l6cA:undetectable | 5w7bD-3l6cA:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6r | SERINE RACEMASE (Homo sapiens) |
PF00291(PALP) | 3 | GLY A 186ASN A 154ARG A 135 | LLP A 56 ( 3.7A)LLP A 56 ( 4.7A)MLI A 347 (-3.0A) | 0.79A | 5w7bD-3l6rA:undetectable | 5w7bD-3l6rA:12.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lvv | GLUTAMATE--CYSTEINELIGASE (Saccharomycescerevisiae) |
PF03074(GCS) | 3 | GLY A 209ASN A 339ARG A 329 | None | 0.75A | 5w7bD-3lvvA:undetectable | 5w7bD-3lvvA:10.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lvv | GLUTAMATE--CYSTEINELIGASE (Saccharomycescerevisiae) |
PF03074(GCS) | 3 | GLY A 344ASN A 339ARG A 329 | None | 0.69A | 5w7bD-3lvvA:undetectable | 5w7bD-3lvvA:10.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT ALPHA6-PHOSPHOFRUCTOKINASE SUBUNIT BETA (Saccharomycescerevisiae) |
PF00365(PFK) | 3 | GLY A 658ASN A 609ARG B 812 | None | 0.68A | 5w7bD-3o8oA:undetectable | 5w7bD-3o8oA:7.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ojy | COMPLEMENT COMPONENTC8 BETA CHAIN (Homo sapiens) |
PF00057(Ldl_recept_a)PF00090(TSP_1)PF01823(MACPF) | 3 | GLY B 88ASN B 87ARG B 157 | None CA B 538 (-2.8A)None | 0.69A | 5w7bD-3ojyB:undetectable | 5w7bD-3ojyB:8.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pen | TRANSLATIONINITIATION FACTOR 2SUBUNIT GAMMA (Sulfolobussolfataricus) |
PF00009(GTP_EFTU)PF03144(GTP_EFTU_D2)PF09173(eIF2_C) | 3 | GLY A 293ASN A 11ARG A 207 | None | 0.57A | 5w7bD-3penA:3.5 | 5w7bD-3penA:13.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qua | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycolicibacteriumsmegmatis) |
PF03641(Lysine_decarbox) | 3 | GLY A 62ASN A 57ARG A 69 | None | 0.76A | 5w7bD-3quaA:undetectable | 5w7bD-3quaA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT LNADH-QUINONEOXIDOREDUCTASESUBUNIT M (Escherichiacoli) |
no annotation | 3 | GLY M 242ASN L 566ARG M 313 | None | 0.67A | 5w7bD-3rkoM:undetectable | 5w7bD-3rkoM:8.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ro8 | ENDO-1,4-BETA-XYLANASE (Paenibacillussp. JDR-2) |
PF00331(Glyco_hydro_10) | 3 | GLY A 230ASN A 192ARG A 301 | None | 0.77A | 5w7bD-3ro8A:undetectable | 5w7bD-3ro8A:11.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v75 | OROTIDINE5'-PHOSPHATEDECARBOXYLASE (Streptomycesavermitilis) |
PF00215(OMPdecase) | 3 | GLY A 194ASN A 187ARG A 144 | None | 0.46A | 5w7bD-3v75A:undetectable | 5w7bD-3v75A:12.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bhh | NUCLEOPROTEIN (Californiaencephalitisorthobunyavirus) |
PF00952(Bunya_nucleocap) | 3 | GLY B 16ASN B 15ARG B 94 | U R 14 ( 4.1A) U R 15 ( 2.8A) U R 16 ( 4.0A) | 0.77A | 5w7bD-4bhhB:undetectable | 5w7bD-4bhhB:16.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cua | BETA-GALACTOSIDASE (Streptococcuspneumoniae) |
no annotation | 3 | GLY A1578ASN A1585ARG A1621 | EDO A2646 (-4.1A)EDO A2646 (-3.5A)EDO A2646 (-3.8A) | 0.72A | 5w7bD-4cuaA:undetectable | 5w7bD-4cuaA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzz | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 3 | GLY A 465ASN A 463ARG A 428 | None | 0.77A | 5w7bD-4hzzA:undetectable | 5w7bD-4hzzA:13.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4imr | 3-OXOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (Agrobacteriumfabrum) |
PF13561(adh_short_C2) | 3 | GLY A 18ASN A 94ARG A 196 | NAP A 300 (-3.2A)NAP A 300 (-3.2A)NAP A 300 (-3.6A) | 0.79A | 5w7bD-4imrA:6.6 | 5w7bD-4imrA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j0m | SERINE/THREONINE-PROTEIN KINASEBRI1-LIKE 1 (Arabidopsisthaliana) |
PF08263(LRRNT_2)PF13516(LRR_6)PF13855(LRR_8) | 3 | GLY A 386ASN A 412ARG A 611 | None | 0.77A | 5w7bD-4j0mA:undetectable | 5w7bD-4j0mA:7.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jg3 | CATABOLITEREPRESSION CONTROLPROTEIN (Pseudomonasaeruginosa) |
PF03372(Exo_endo_phos) | 3 | GLY A 219ASN A 217ARG A 245 | None | 0.75A | 5w7bD-4jg3A:undetectable | 5w7bD-4jg3A:13.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3c | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA ([Haemophilus]ducreyi) |
PF01103(Bac_surface_Ag)PF07244(POTRA) | 3 | GLY A 448ASN A 445ARG A 364 | None | 0.68A | 5w7bD-4k3cA:undetectable | 5w7bD-4k3cA:9.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3j | HEPATOCYTE GROWTHFACTOR BETA CHAIN (Homo sapiens) |
PF01403(Sema)PF01437(PSI) | 3 | GLY B 198ASN B 199ARG B 217 | None | 0.72A | 5w7bD-4k3jB:undetectable | 5w7bD-4k3jB:9.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3y | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 3 | GLY A 369ASN A 367ARG A 327 | None | 0.74A | 5w7bD-4k3yA:undetectable | 5w7bD-4k3yA:12.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k68 | GH10 XYLANASE (soil metagenome) |
PF00331(Glyco_hydro_10) | 3 | GLY A 238ASN A 207ARG A 333 | None | 0.74A | 5w7bD-4k68A:undetectable | 5w7bD-4k68A:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kh3 | ANTIGEN 43 (Escherichiacoli) |
PF16168(AIDA) | 3 | GLY A 341ASN A 321ARG A 393 | None | 0.54A | 5w7bD-4kh3A:undetectable | 5w7bD-4kh3A:8.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mlg | BETA-XYLOSIDASE (unculturedorganism) |
PF04616(Glyco_hydro_43) | 3 | GLY A 43ASN A 42ARG A 81 | None | 0.67A | 5w7bD-4mlgA:undetectable | 5w7bD-4mlgA:13.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n42 | XYLANASE ANDALPHA-AMYLASEINHIBITOR PROTEINISOFORM III (Scadoxusmultiflorus) |
PF00704(Glyco_hydro_18) | 3 | GLY A 25ASN A 26ARG A 16 | None | 0.74A | 5w7bD-4n42A:undetectable | 5w7bD-4n42A:13.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4og1 | ENOYL-COAHYDRATASE/ISOMERASE (Novosphingobiumaromaticivorans) |
PF00378(ECH_1) | 3 | GLY A 161ASN A 162ARG A 104 | None | 0.72A | 5w7bD-4og1A:undetectable | 5w7bD-4og1A:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q63 | UNCHARACTERIZEDPROTEIN LPG0364 (Legionellapneumophila) |
PF07238(PilZ) | 3 | GLY A 14ASN A 12ARG A 97 | None | 0.78A | 5w7bD-4q63A:undetectable | 5w7bD-4q63A:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qb5 | GLYOXALASE/BLEOMYCINRESISTANCEPROTEIN/DIOXYGENASE (Rhodoferaxferrireducens) |
PF00903(Glyoxalase) | 3 | GLY A 63ASN A 62ARG A 111 | None | 0.77A | 5w7bD-4qb5A:undetectable | 5w7bD-4qb5A:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rvw | ZNUD (Neisseriameningitidis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 3 | GLY A 67ASN A 48ARG A 232 | None | 0.44A | 5w7bD-4rvwA:undetectable | 5w7bD-4rvwA:7.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w1t | COPPER OXIDASE (Streptomycessviceus) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 3 | GLY A 297ASN A 207ARG A 200 | None | 0.62A | 5w7bD-4w1tA:undetectable | 5w7bD-4w1tA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd9 | NISIN BIOSYNTHESISPROTEIN NISB (Lactococcuslactis) |
PF04738(Lant_dehydr_N)PF14028(Lant_dehydr_C) | 3 | GLY A 460ASN A 457ARG A 516 | None | 0.69A | 5w7bD-4wd9A:undetectable | 5w7bD-4wd9A:5.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xqk | LLABIII (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII)PF13156(Mrr_cat_2) | 3 | GLY A 367ASN A 362ARG A 198 | None | 0.77A | 5w7bD-4xqkA:undetectable | 5w7bD-4xqkA:4.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwt | DR2417 (Deinococcusradiodurans) |
PF00753(Lactamase_B)PF07521(RMMBL) | 3 | GLY A 183ASN A 254ARG A 261 | None | 0.76A | 5w7bD-4xwtA:undetectable | 5w7bD-4xwtA:8.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y4v | CONSERVEDHYPOTHETICALSECRETED PROTEIN (Helicobacterpylori) |
PF03734(YkuD) | 3 | GLY A 161ASN A 181ARG A 168 | None | 0.74A | 5w7bD-4y4vA:undetectable | 5w7bD-4y4vA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zro | 3C-LIKE PROTEINASE (Alphacoronavirus1) |
PF05409(Peptidase_C30) | 3 | GLY A 169ASN A 168ARG A 130 | None | 0.75A | 5w7bD-4zroA:undetectable | 5w7bD-4zroA:12.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5afu | DYNACTIN (Sus scrofa) |
PF00022(Actin) | 3 | GLY A 17ASN A 37ARG A 188 | ADP A 800 ( 3.1A)NoneNone | 0.65A | 5w7bD-5afuA:undetectable | 5w7bD-5afuA:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ah0 | LIPASE (Pelosinusfermentans) |
no annotation | 3 | GLY A 221ASN A 223ARG A 236 | None | 0.72A | 5w7bD-5ah0A:2.2 | 5w7bD-5ah0A:13.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c7o | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Homo sapiens) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 3 | GLY O 214ASN O 212ARG O 406 | None | 0.78A | 5w7bD-5c7oO:undetectable | 5w7bD-5c7oO:10.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c8c | VP0VP1 (Enterovirus A) |
PF00073(Rhv)PF02226(Pico_P1A) | 3 | GLY B 202ASN A 278ARG A 267 | None | 0.79A | 5w7bD-5c8cB:undetectable | 5w7bD-5c8cB:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqq | TWO PORE CALCIUMCHANNEL PROTEIN 1 (Arabidopsisthaliana) |
PF00520(Ion_trans) | 3 | GLY A 487ASN A 490ARG A 428 | None | 0.74A | 5w7bD-5dqqA:undetectable | 5w7bD-5dqqA:7.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ffj | ENDONUCLEASE ANDMETHYLASE LLAGI (Lactococcuslactis) |
PF00271(Helicase_C)PF02384(N6_Mtase)PF04851(ResIII) | 3 | GLY A 367ASN A 362ARG A 198 | None | 0.63A | 5w7bD-5ffjA:undetectable | 5w7bD-5ffjA:4.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fku | DNA POLYMERASE IIISUBUNIT ALPHA (Escherichiacoli) |
PF01336(tRNA_anti-codon)PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 3 | GLY A 703ASN A 393ARG A 709 | None | 0.64A | 5w7bD-5fkuA:undetectable | 5w7bD-5fkuA:5.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gkk | PUTATIVE HOMINGENDONUCLEASE (Thermotoganeapolitana) |
PF00961(LAGLIDADG_1) | 3 | GLY A 21ASN A 135ARG A 39 | None | 0.71A | 5w7bD-5gkkA:undetectable | 5w7bD-5gkkA:18.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gzs | GGDEF FAMILY PROTEIN (Vibrio cholerae) |
PF00497(SBP_bac_3) | 3 | GLY A 468ASN A 465ARG A 269 | None | 0.79A | 5w7bD-5gzsA:undetectable | 5w7bD-5gzsA:9.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jlt | MIDDLE TRANSCRIPTIONREGULATORY PROTEINMOTA (Escherichiavirus T4) |
PF09158(MotCF) | 3 | GLY A 188ASN A 187ARG A 150 | None | 0.79A | 5w7bD-5jltA:undetectable | 5w7bD-5jltA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jm0 | ALPHA-MANNOSIDASE,ALPHA-MANNOSIDASE,ALPHA-MANNOSIDASE (Saccharomycescerevisiae) |
PF01074(Glyco_hydro_38)PF07748(Glyco_hydro_38C)PF09261(Alpha-mann_mid) | 3 | GLY A 414ASN A 378ARG A 867 | None | 0.60A | 5w7bD-5jm0A:undetectable | 5w7bD-5jm0A:5.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k2y | PROBABLE PERIPLASMICSUGAR-BINDINGLIPOPROTEIN USPC (Mycobacteriumtuberculosis) |
PF01547(SBP_bac_1) | 3 | GLY A 230ASN A 242ARG A 234 | None | 0.61A | 5w7bD-5k2yA:undetectable | 5w7bD-5k2yA:14.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kdx | METALLOPEPTIDASE (Pseudomonasaeruginosa) |
PF13402(Peptidase_M60) | 3 | GLY A 368ASN A 109ARG A 237 | PO4 A1004 (-3.3A)NoneNone | 0.72A | 5w7bD-5kdxA:undetectable | 5w7bD-5kdxA:6.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mvh | BACCELL_00856 (Bacteroidescellulosilyticus) |
PF15892(BNR_4) | 3 | GLY A 304ASN A 280ARG A 230 | None | 0.79A | 5w7bD-5mvhA:undetectable | 5w7bD-5mvhA:10.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nqa | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 4 (Homo sapiens) |
no annotation | 3 | GLY A 335ASN A 378ARG A 209 | EDO A 628 (-3.5A)NoneNone | 0.80A | 5w7bD-5nqaA:undetectable | 5w7bD-5nqaA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oyn | DEHYDRATASE,ILVD/EDD FAMILY (Caulobactervibrioides) |
no annotation | 3 | GLY A 127ASN A 211ARG A 234 | None | 0.65A | 5w7bD-5oynA:undetectable | 5w7bD-5oynA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vf3 | CAPSID VERTEXPROTEIN GP24 (Escherichiavirus T4) |
PF07068(Gp23) | 3 | GLY a 191ASN a 190ARG a 21 | None | 0.68A | 5w7bD-5vf3a:undetectable | 5w7bD-5vf3a:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w1a | MYOSIN HEAVY CHAIN,MUSCLE (Drosophilamelanogaster) |
no annotation | 3 | GLY A 463ASN A 481ARG A 672 | None | 0.79A | 5w7bD-5w1aA:undetectable | 5w7bD-5w1aA:17.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w7a | ACYLOXYACYLHYDROLASE LARGESUBUNIT (Oryctolaguscuniculus) |
no annotation | 3 | GLY B 340ASN B 372ARG B 378 | FTT B 609 ( 3.3A)FTT B 609 (-3.1A)PO4 B 607 (-3.3A) | 0.17A | 5w7bD-5w7aB:65.6 | 5w7bD-5w7aB:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8o | HOMOSERINEO-ACETYLTRANSFERASE (Mycolicibacteriumhassiacum) |
PF00561(Abhydrolase_1) | 3 | GLY A 105ASN A 101ARG A 162 | None | 0.55A | 5w7bD-5w8oA:2.8 | 5w7bD-5w8oA:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w8p | HOMOSERINEO-ACETYLTRANSFERASE (Mycobacteroidesabscessus) |
PF00561(Abhydrolase_1) | 3 | GLY A 108ASN A 104ARG A 165 | GOL A 407 (-4.7A)GOL A 407 ( 4.8A)None | 0.61A | 5w7bD-5w8pA:3.4 | 5w7bD-5w8pA:12.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xa1 | INOSITOL1,4,5-TRISPHOSPHATERECEPTOR TYPE 1 (Mus musculus) |
PF01365(RYDR_ITPR)PF02815(MIR)PF08709(Ins145_P3_rec) | 3 | GLY A 158ASN A 156ARG A 137 | None | 0.68A | 5w7bD-5xa1A:undetectable | 5w7bD-5xa1A:4.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xcy | GLUCANASE (Phanerochaetechrysosporium) |
PF01341(Glyco_hydro_6) | 3 | GLY A 349ASN A 436ARG A 371 | None | 0.80A | 5w7bD-5xcyA:3.3 | 5w7bD-5xcyA:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xkt | UREASE ACCESSORYPROTEIN UREG (Klebsiellapneumoniae) |
no annotation | 3 | GLY A 96ASN A 97ARG A 63 | None | 0.77A | 5w7bD-5xktA:2.3 | 5w7bD-5xktA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z4i | UBIQUITINCARBOXYL-TERMINALHYDROLASE 20 (Homo sapiens) |
no annotation | 3 | GLY A 54ASN A 39ARG A 80 | None | 0.69A | 5w7bD-5z4iA:undetectable | 5w7bD-5z4iA:19.10 |