SIMILAR PATTERNS OF AMINO ACIDS FOR 5VVN_B_H4BB502
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a88 | CHLOROPEROXIDASE L (Streptomyceslividans) |
PF00561(Abhydrolase_1) | 4 | PHE A 207GLU A 204SER A 203ARG A 104 | None | 1.36A | 5vvnA-1a88A:0.05vvnB-1a88A:0.0 | 5vvnA-1a88A:20.415vvnB-1a88A:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a8s | CHLOROPEROXIDASE F (Pseudomonasfluorescens) |
PF00561(Abhydrolase_1) | 4 | PHE A 205GLU A 202SER A 201ARG A 102 | None | 1.41A | 5vvnA-1a8sA:0.05vvnB-1a8sA:0.0 | 5vvnA-1a8sA:21.625vvnB-1a8sA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bg6 | N-(1-D-CARBOXYLETHYL)-L-NORVALINEDEHYDROGENASE (Arthrobactersp. 1C) |
PF02317(Octopine_DH)PF02558(ApbA) | 4 | PHE A 248GLU A 359SER A 356VAL A 358 | None | 1.35A | 5vvnA-1bg6A:0.05vvnB-1bg6A:0.0 | 5vvnA-1bg6A:22.865vvnB-1bg6A:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hkh | GAMMA LACTAMASE (Microbacterium) |
PF00561(Abhydrolase_1) | 4 | GLU A 213SER A 210VAL A 212ARG A 241 | None | 1.42A | 5vvnA-1hkhA:0.05vvnB-1hkhA:0.0 | 5vvnA-1hkhA:19.955vvnB-1hkhA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hv5 | STROMELYSIN 3 (Mus musculus) |
PF00413(Peptidase_M10) | 4 | GLU A 143SER A 142VAL A 140TRP A 141 | None | 1.32A | 5vvnA-1hv5A:0.35vvnB-1hv5A:0.0 | 5vvnA-1hv5A:18.375vvnB-1hv5A:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j85 | YIBK (Haemophilusinfluenzae) |
PF00588(SpoU_methylase) | 4 | PHE A 76GLU A 143SER A 87ARG A 74 | None | 1.31A | 5vvnA-1j85A:undetectable5vvnB-1j85A:0.0 | 5vvnA-1j85A:15.545vvnB-1j85A:15.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1juh | QUERCETIN2,3-DIOXYGENASE (Aspergillusjaponicus) |
no annotation | 4 | GLU A 314SER A 313VAL A 284ARG A 20 | None | 1.34A | 5vvnA-1juhA:undetectable5vvnB-1juhA:0.0 | 5vvnA-1juhA:21.855vvnB-1juhA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k38 | BETA-LACTAMASE OXA-2 (Salmonellaenterica) |
PF00905(Transpeptidase) | 4 | TRP A 214GLU A 209SER A 64ARG A 58 | None | 1.22A | 5vvnA-1k38A:0.25vvnB-1k38A:0.0 | 5vvnA-1k38A:20.325vvnB-1k38A:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kfu | M-CALPAIN LARGESUBUNIT (Homo sapiens) |
PF00648(Peptidase_C2)PF01067(Calpain_III)PF13833(EF-hand_8) | 4 | PHE L 502GLU L 339SER L 236ARG L 500 | None | 1.03A | 5vvnA-1kfuL:undetectable5vvnB-1kfuL:undetectable | 5vvnA-1kfuL:20.915vvnB-1kfuL:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l5j | ACONITATE HYDRATASE2 (Escherichiacoli) |
PF00330(Aconitase)PF06434(Aconitase_2_N)PF11791(Aconitase_B_N) | 4 | TRP A 155PHE A 156GLU A 154ARG A 340 | None | 1.37A | 5vvnA-1l5jA:undetectable5vvnB-1l5jA:undetectable | 5vvnA-1l5jA:20.215vvnB-1l5jA:20.21 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1m9q | ENDOTHELIALNITRIC-OXIDESYNTHASE (Homo sapiens) |
PF02898(NO_synthase) | 4 | SER A 102VAL A 104ARG A 365TRP A 447 | NoneMPD A 605 (-4.7A)MPD A 605 ( 4.7A)MPD A 605 ( 4.0A) | 0.27A | 5vvnA-1m9qA:62.25vvnB-1m9qA:62.2 | 5vvnA-1m9qA:95.175vvnB-1m9qA:95.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nmb | N9 NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | PHE N 352GLU N 229SER N 228VAL N 122 | None | 1.45A | 5vvnA-1nmbN:undetectable5vvnB-1nmbN:undetectable | 5vvnA-1nmbN:21.855vvnB-1nmbN:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrk | YGFZ PROTEIN (Escherichiacoli) |
PF01571(GCV_T) | 4 | PHE A 154VAL A 200ARG A 160TRP A 27 | SO4 A 400 (-4.6A)NoneNoneSO4 A 400 (-3.4A) | 1.32A | 5vvnA-1nrkA:undetectable5vvnB-1nrkA:undetectable | 5vvnA-1nrkA:21.245vvnB-1nrkA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ovl | ORPHAN NUCLEARRECEPTOR NURR1 (MSE496, 511) (Homo sapiens) |
PF00104(Hormone_recep) | 4 | TRP B 482PHE B 479SER B 485VAL B 487 | None K B 703 ( 4.8A)NoneNone | 1.22A | 5vvnA-1ovlB:undetectable5vvnB-1ovlB:undetectable | 5vvnA-1ovlB:19.515vvnB-1ovlB:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua7 | ALPHA-AMYLASE (Bacillussubtilis) |
PF00128(Alpha-amylase) | 4 | GLU A 113SER A 116VAL A 114TRP A 120 | None | 1.34A | 5vvnA-1ua7A:undetectable5vvnB-1ua7A:undetectable | 5vvnA-1ua7A:21.285vvnB-1ua7A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1n | 4-ALPHA-GLUCANOTRANSFERASE (Solanumtuberosum) |
PF02446(Glyco_hydro_77) | 4 | TRP A 286SER A 272VAL A 332TRP A 330 | GOL A1002 (-3.4A)NoneNoneNone | 1.36A | 5vvnA-1x1nA:undetectable5vvnB-1x1nA:undetectable | 5vvnA-1x1nA:22.205vvnB-1x1nA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc5 | NUCLEAR RECEPTORCOREPRESSOR 2 (Homo sapiens) |
PF00249(Myb_DNA-binding) | 4 | GLU A 436SER A 433VAL A 428TRP A 432 | None | 1.18A | 5vvnA-1xc5A:undetectable5vvnB-1xc5A:undetectable | 5vvnA-1xc5A:10.975vvnB-1xc5A:10.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yks | GENOME POLYPROTEIN[CONTAINS:FLAVIVIRIN PROTEASENS3 CATALYTICSUBUNIT] (Yellow fevervirus) |
PF00271(Helicase_C)PF07652(Flavi_DEAD) | 4 | PHE A 240GLU A 235SER A 234VAL A 232 | None | 1.29A | 5vvnA-1yksA:undetectable5vvnB-1yksA:undetectable | 5vvnA-1yksA:21.885vvnB-1yksA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zzg | GLUCOSE-6-PHOSPHATEISOMERASE (Thermusthermophilus) |
PF00342(PGI) | 4 | PHE A 188GLU A 183SER A 39ARG A 187 | None | 1.45A | 5vvnA-1zzgA:undetectable5vvnB-1zzgA:undetectable | 5vvnA-1zzgA:21.115vvnB-1zzgA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c6s | ADENOVIRUS 2,12PENTON BASE CHIMERA (HumanmastadenovirusC) |
PF01686(Adeno_Penton_B) | 4 | PHE A 412GLU A 177SER A 176VAL A 367 | None | 1.36A | 5vvnA-2c6sA:undetectable5vvnB-2c6sA:undetectable | 5vvnA-2c6sA:20.955vvnB-2c6sA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d52 | PENTAKETIDE CHROMONESYNTHASE (Aloearborescens) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | PHE A 83GLU A 87VAL A 52ARG A 81 | None | 1.32A | 5vvnA-2d52A:undetectable5vvnB-2d52A:undetectable | 5vvnA-2d52A:21.895vvnB-2d52A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d9j | REGULATOR OFG-PROTEIN SIGNALLING7 (Homo sapiens) |
PF00615(RGS) | 4 | PHE A 123GLU A 30VAL A 27TRP A 15 | None | 1.39A | 5vvnA-2d9jA:undetectable5vvnB-2d9jA:undetectable | 5vvnA-2d9jA:17.605vvnB-2d9jA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ebw | DNA REPAIR PROTEINREV1 (Homo sapiens) |
PF16589(BRCT_2) | 4 | TRP A 113GLU A 116SER A 117VAL A 115 | None | 1.24A | 5vvnA-2ebwA:undetectable5vvnB-2ebwA:undetectable | 5vvnA-2ebwA:13.615vvnB-2ebwA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2glf | PROBABLE M18-FAMILYAMINOPEPTIDASE 1 (Thermotogamaritima) |
PF02127(Peptidase_M18) | 4 | PHE A 233GLU A 431SER A 428TRP A 129 | None | 1.24A | 5vvnA-2glfA:undetectable5vvnB-2glfA:undetectable | 5vvnA-2glfA:21.345vvnB-2glfA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2inc | TOLUENE, O-XYLENEMONOOXYGENASEOXYGENASE SUBUNIT (Pseudomonasstutzeri) |
PF02332(Phenol_Hydrox)PF04945(YHS) | 4 | PHE A 29GLU A 27VAL A 23ARG A 116 | None | 1.20A | 5vvnA-2incA:undetectable5vvnB-2incA:undetectable | 5vvnA-2incA:20.595vvnB-2incA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ixn | SERINE/THREONINE-PROTEIN PHOSPHATASE 2AACTIVATOR 2 (Saccharomycescerevisiae) |
PF03095(PTPA) | 4 | TRP A 16PHE A 291SER A 283VAL A 281 | None | 1.42A | 5vvnA-2ixnA:undetectable5vvnB-2ixnA:undetectable | 5vvnA-2ixnA:20.215vvnB-2ixnA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jnz | PHL P 3 ALLERGEN (Phleum pratense) |
PF01357(Pollen_allerg_1) | 4 | PHE A 76GLU A 55SER A 68VAL A 66 | None | 1.42A | 5vvnA-2jnzA:undetectable5vvnB-2jnzA:undetectable | 5vvnA-2jnzA:12.445vvnB-2jnzA:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbk | KSHV PROTEASE (Humangammaherpesvirus8) |
PF00716(Peptidase_S21) | 4 | PHE A 59GLU A 168SER A 167VAL A 164 | None | 1.42A | 5vvnA-2pbkA:undetectable5vvnB-2pbkA:undetectable | 5vvnA-2pbkA:19.865vvnB-2pbkA:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rtt | CHIC (Streptomycescoelicolor) |
PF00553(CBM_2) | 4 | PHE A 41GLU A 38VAL A 37TRP A 22 | None | 1.45A | 5vvnA-2rttA:undetectable5vvnB-2rttA:undetectable | 5vvnA-2rttA:15.255vvnB-2rttA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vut | NITROGEN METABOLITEREPRESSION REGULATORNMRA (Aspergillusnidulans) |
PF05368(NmrA) | 4 | PHE A 181SER A 224VAL A 228TRP A 189 | None | 1.23A | 5vvnA-2vutA:undetectable5vvnB-2vutA:undetectable | 5vvnA-2vutA:22.365vvnB-2vutA:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wjv | REGULATOR OFNONSENSE TRANSCRIPTS1 (Homo sapiens) |
PF04851(ResIII)PF09416(UPF1_Zn_bind)PF13086(AAA_11)PF13087(AAA_12) | 4 | TRP A 241PHE A 196SER A 240VAL A 243 | None | 1.35A | 5vvnA-2wjvA:undetectable5vvnB-2wjvA:undetectable | 5vvnA-2wjvA:20.375vvnB-2wjvA:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xbl | PHOSPHOHEPTOSEISOMERASE (Burkholderiapseudomallei) |
PF13580(SIS_2) | 4 | PHE A 135GLU A 137SER A 106VAL A 109 | None | 1.11A | 5vvnA-2xblA:undetectable5vvnB-2xblA:undetectable | 5vvnA-2xblA:19.815vvnB-2xblA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xqx | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE D (Streptococcuspneumoniae) |
PF00754(F5_F8_type_C) | 4 | TRP A 840PHE A 816GLU A 826VAL A 811 | None | 1.46A | 5vvnA-2xqxA:undetectable5vvnB-2xqxA:undetectable | 5vvnA-2xqxA:15.235vvnB-2xqxA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z23 | PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Yersinia pestis) |
PF00496(SBP_bac_5) | 4 | TRP A 397PHE A 400GLU A 396SER A 21 | None | 1.44A | 5vvnA-2z23A:undetectable5vvnB-2z23A:undetectable | 5vvnA-2z23A:19.315vvnB-2z23A:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ckb | SUSD (Bacteroidesthetaiotaomicron) |
PF07980(SusD_RagB) | 4 | TRP A 485PHE A 489GLU A 484ARG A 437 | None | 1.06A | 5vvnA-3ckbA:undetectable5vvnB-3ckbA:undetectable | 5vvnA-3ckbA:21.885vvnB-3ckbA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euw | MYO-INOSITOLDEHYDROGENASE (Corynebacteriumglutamicum) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | PHE A 59GLU A 57SER A 54VAL A 52 | None | 1.09A | 5vvnA-3euwA:undetectable5vvnB-3euwA:undetectable | 5vvnA-3euwA:20.515vvnB-3euwA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1n | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
PF00632(HECT) | 4 | PHE A4109GLU A4033VAL A4019TRP A4065 | None | 1.33A | 5vvnA-3g1nA:undetectable5vvnB-3g1nA:undetectable | 5vvnA-3g1nA:21.685vvnB-3g1nA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gz7 | PUTATIVE ANTIBIOTICBIOSYNTHESISMONOOXYGENASE (Bordetellabronchiseptica) |
PF03992(ABM) | 4 | PHE A 83SER A 7VAL A 89ARG A 76 | CIT A 97 (-4.7A)NoneNoneCIT A 97 (-3.8A) | 1.27A | 5vvnA-3gz7A:undetectable5vvnB-3gz7A:undetectable | 5vvnA-3gz7A:12.845vvnB-3gz7A:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hcy | PUTATIVETWO-COMPONENT SENSORHISTIDINE KINASEPROTEIN (Sinorhizobiummeliloti) |
PF13185(GAF_2) | 4 | PHE A 74GLU A 80SER A 81VAL A 83 | None | 1.05A | 5vvnA-3hcyA:undetectable5vvnB-3hcyA:undetectable | 5vvnA-3hcyA:18.185vvnB-3hcyA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hpf | MUCONATECYCLOISOMERASE (Oceanobacillusiheyensis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | PHE A 183GLU A 181SER A 177ARG A 151 | None | 1.35A | 5vvnA-3hpfA:undetectable5vvnB-3hpfA:undetectable | 5vvnA-3hpfA:20.335vvnB-3hpfA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if6 | OXA-46 OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 4 | TRP C 219GLU C 214SER C 69ARG C 63 | None | 1.11A | 5vvnA-3if6C:undetectable5vvnB-3if6C:undetectable | 5vvnA-3if6C:21.765vvnB-3if6C:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lcc | PUTATIVE METHYLCHLORIDE TRANSFERASE (Arabidopsisthaliana) |
PF05724(TPMT) | 4 | PHE A 133GLU A 122VAL A 120ARG A 69 | None | 1.35A | 5vvnA-3lccA:undetectable5vvnB-3lccA:undetectable | 5vvnA-3lccA:18.045vvnB-3lccA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0g | ISOPRENE SYNTHASE (Populus tremulax Populus alba) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | PHE A 155GLU A 168SER A 171ARG A 159 | None | 1.18A | 5vvnA-3n0gA:undetectable5vvnB-3n0gA:undetectable | 5vvnA-3n0gA:21.045vvnB-3n0gA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0q | PUTATIVEAROMATIC-RINGHYDROXYLATINGDIOXYGENASE (Ruegeria sp.TM1040) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A) | 4 | TRP A 391PHE A 388GLU A 390SER A 394 | NoneNoneGOL A 507 (-2.5A)None | 1.10A | 5vvnA-3n0qA:undetectable5vvnB-3n0qA:undetectable | 5vvnA-3n0qA:22.715vvnB-3n0qA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obe | SUGAR PHOSPHATEISOMERASE/EPIMERASE (Parabacteroidesdistasonis) |
PF01261(AP_endonuc_2) | 4 | PHE A 137GLU A 175SER A 174VAL A 172 | None | 1.44A | 5vvnA-3obeA:undetectable5vvnB-3obeA:undetectable | 5vvnA-3obeA:19.785vvnB-3obeA:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vh1 | UBIQUITIN-LIKEMODIFIER-ACTIVATINGENZYME ATG7 (Saccharomycescerevisiae) |
PF00899(ThiF)PF16420(ATG7_N) | 4 | PHE A 172SER A 177VAL A 78TRP A 179 | None | 1.23A | 5vvnA-3vh1A:undetectable5vvnB-3vh1A:undetectable | 5vvnA-3vh1A:22.185vvnB-3vh1A:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vv4 | METHYL-ACCEPTINGCHEMOTAXIS PROTEIN (Thermosynechococcuselongatus) |
PF01590(GAF) | 4 | PHE A 67GLU A 73VAL A 72TRP A 71 | NoneNoneNonePVG A 201 (-3.6A) | 1.05A | 5vvnA-3vv4A:undetectable5vvnB-3vv4A:undetectable | 5vvnA-3vv4A:19.965vvnB-3vv4A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w0s | HYGROMYCIN-B4-O-KINASE (Escherichiacoli) |
PF01636(APH) | 4 | PHE A 136GLU A 219SER A 218TRP A 217 | NoneHY0 A 401 (-4.0A)HY0 A 401 (-3.5A)None | 1.19A | 5vvnA-3w0sA:undetectable5vvnB-3w0sA:undetectable | 5vvnA-3w0sA:21.965vvnB-3w0sA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wsy | SORTILIN-RELATEDRECEPTOR (Homo sapiens) |
PF15901(Sortilin_C)PF15902(Sortilin-Vps10) | 4 | PHE A 278GLU A 267SER A 275VAL A 297 | None | 1.34A | 5vvnA-3wsyA:undetectable5vvnB-3wsyA:undetectable | 5vvnA-3wsyA:21.345vvnB-3wsyA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq6 | PUTATIVE ARSENICALPUMP-DRIVING ATPASE (Methanothermobacterthermautotrophicus) |
PF02374(ArsA_ATPase) | 4 | PHE A 158SER A 164VAL A 166TRP A 165 | None | 0.91A | 5vvnA-3zq6A:undetectable5vvnB-3zq6A:undetectable | 5vvnA-3zq6A:21.235vvnB-3zq6A:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aco | CENTROMEREDNA-BINDING PROTEINCOMPLEX CBF3 SUBUNITA (Saccharomycescerevisiae) |
PF16787(NDC10_II) | 4 | PHE A 359GLU A 229SER A 232ARG A 355 | None | 1.39A | 5vvnA-4acoA:undetectable5vvnB-4acoA:undetectable | 5vvnA-4acoA:16.705vvnB-4acoA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cu8 | GLYCOSIDE HYDROLASE2 (Streptococcuspneumoniae) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF16355(DUF4982) | 4 | PHE A 522SER A 240VAL A 281ARG A 521 | None | 1.16A | 5vvnA-4cu8A:undetectable5vvnB-4cu8A:undetectable | 5vvnA-4cu8A:19.795vvnB-4cu8A:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eei | ADENYLOSUCCINATELYASE (Francisellatularensis) |
PF00206(Lyase_1) | 4 | PHE A 80GLU A 78SER A 75ARG A 50 | None | 1.41A | 5vvnA-4eeiA:undetectable5vvnB-4eeiA:undetectable | 5vvnA-4eeiA:20.545vvnB-4eeiA:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f9d | POLY-BETA-1,6-N-ACETYL-D-GLUCOSAMINEN-DEACETYLASE (Escherichiacoli) |
PF01522(Polysacc_deac_1)PF14883(GHL13) | 4 | TRP A 54PHE A 301SER A 53VAL A 290 | NoneNoneACY A 702 ( 4.9A)None | 1.34A | 5vvnA-4f9dA:undetectable5vvnB-4f9dA:undetectable | 5vvnA-4f9dA:21.005vvnB-4f9dA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4go4 | PUTATIVEGAMMA-HYDROXYMUCONICSEMIALDEHYDEDEHYDROGENASE (Pseudomonas sp.WBC-3) |
PF00171(Aldedh) | 4 | TRP A 148GLU A 175SER A 174ARG A 331 | NAD A 601 (-4.0A)NAD A 601 (-3.7A)NAD A 601 (-3.8A)None | 1.46A | 5vvnA-4go4A:undetectable5vvnB-4go4A:undetectable | 5vvnA-4go4A:19.575vvnB-4go4A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs1 | DYP-TYPE PEROXIDASE (Thermobifidacellulosilytica) |
PF04261(Dyp_perox) | 4 | GLU A 393SER A 390VAL A 392ARG A 278 | None | 1.34A | 5vvnA-4gs1A:undetectable5vvnB-4gs1A:undetectable | 5vvnA-4gs1A:20.515vvnB-4gs1A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs1 | DYP-TYPE PEROXIDASE (Thermobifidacellulosilytica) |
PF04261(Dyp_perox) | 4 | PHE A 384SER A 390VAL A 392ARG A 278 | HEM A 501 (-4.0A)NoneNoneNone | 0.90A | 5vvnA-4gs1A:undetectable5vvnB-4gs1A:undetectable | 5vvnA-4gs1A:20.515vvnB-4gs1A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gym | GLYOXALASE/BLEOMYCINRESISTANCEPROTEIN/DIOXYGENASE (Conexibacterwoesei) |
no annotation | 4 | PHE A 91GLU A 126SER A 116TRP A 125 | None | 1.28A | 5vvnA-4gymA:undetectable5vvnB-4gymA:undetectable | 5vvnA-4gymA:16.125vvnB-4gymA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hem | ANTI-BASEPLATETP901-1 LLAMA VHH 02 (Lama glama) |
PF07686(V-set) | 4 | GLU E 26SER E 25VAL E 2ARG E 72 | None | 1.42A | 5vvnA-4hemE:undetectable5vvnB-4hemE:undetectable | 5vvnA-4hemE:17.175vvnB-4hemE:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hsq | PUTATIVE FIMBRIALSUBUNIT (Corynebacteriumdiphtheriae) |
PF16569(GramPos_pilinBB) | 4 | GLU A 441SER A 431VAL A 442ARG A 288 | None | 1.27A | 5vvnA-4hsqA:undetectable5vvnB-4hsqA:undetectable | 5vvnA-4hsqA:19.915vvnB-4hsqA:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hss | PUTATIVE FIMBRIALSUBUNIT (Corynebacteriumdiphtheriae) |
no annotation | 4 | GLU A 441SER A 431VAL A 442ARG A 288 | None | 1.39A | 5vvnA-4hssA:undetectable5vvnB-4hssA:undetectable | 5vvnA-4hssA:22.115vvnB-4hssA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7c | AMINOPEPTIDASE C (Lactobacillusrhamnosus) |
PF03051(Peptidase_C1_2) | 4 | PHE A 397GLU A 384SER A 386VAL A 61 | None | 1.23A | 5vvnA-4k7cA:undetectable5vvnB-4k7cA:undetectable | 5vvnA-4k7cA:20.995vvnB-4k7cA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kdz | TRNA(CYTIDINE(34)-2'-O)-METHYLTRANSFERASE (Escherichiacoli) |
PF00588(SpoU_methylase) | 4 | PHE A 76GLU A 143SER A 87ARG A 74 | None | 1.19A | 5vvnA-4kdzA:undetectable5vvnB-4kdzA:undetectable | 5vvnA-4kdzA:15.805vvnB-4kdzA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nk2 | HEMOGLOBIN-LIKEPROTEIN (Methylacidiphiluminfernorum) |
PF01152(Bac_globin) | 4 | GLU A 186SER A 185VAL A 182TRP A 159 | None | 1.24A | 5vvnA-4nk2A:undetectable5vvnB-4nk2A:undetectable | 5vvnA-4nk2A:19.445vvnB-4nk2A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nk2 | HEMOGLOBIN-LIKEPROTEIN (Methylacidiphiluminfernorum) |
PF01152(Bac_globin) | 4 | PHE A 191GLU A 186SER A 185VAL A 182 | None | 1.18A | 5vvnA-4nk2A:undetectable5vvnB-4nk2A:undetectable | 5vvnA-4nk2A:19.445vvnB-4nk2A:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nob | POLYMERICIMMUNOGLOBULINRECEPTOR (Mus musculus) |
PF07686(V-set) | 4 | GLU A 126SER A 29VAL A 127ARG A 57 | MG A 202 (-2.6A)NoneNoneEDO A 204 (-4.0A) | 1.43A | 5vvnA-4nobA:undetectable5vvnB-4nobA:undetectable | 5vvnA-4nobA:15.725vvnB-4nobA:15.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6x | ANKYRIN-3 (Homo sapiens) |
PF00531(Death) | 4 | PHE A 28GLU A 25VAL A 71ARG A 58 | None | 1.20A | 5vvnA-4o6xA:undetectable5vvnB-4o6xA:undetectable | 5vvnA-4o6xA:13.545vvnB-4o6xA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oxc | E3 UBIQUITIN-PROTEINLIGASE XIAP (Homo sapiens) |
PF00653(BIR) | 4 | PHE A 33SER A 40VAL A 42TRP A 73 | None | 1.29A | 5vvnA-4oxcA:undetectable5vvnB-4oxcA:undetectable | 5vvnA-4oxcA:11.965vvnB-4oxcA:11.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p3h | KSHV PROTEASE (Humangammaherpesvirus8) |
PF00716(Peptidase_S21) | 4 | PHE A 59GLU A 168SER A 167VAL A 164 | None | 1.43A | 5vvnA-4p3hA:undetectable5vvnB-4p3hA:undetectable | 5vvnA-4p3hA:17.815vvnB-4p3hA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxv | HYPOTHETICAL PROTEINLPG0944 (Legionellapneumophila) |
no annotation | 4 | TRP A 62PHE A 59SER A 99VAL A 21 | None | 1.34A | 5vvnA-4rxvA:undetectable5vvnB-4rxvA:undetectable | 5vvnA-4rxvA:19.735vvnB-4rxvA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tq5 | PRENYLTRANSFERASE (Archaeoglobusfulgidus) |
PF01040(UbiA) | 4 | TRP A 60PHE A 57SER A 64TRP A 26 | None | 1.38A | 5vvnA-4tq5A:1.15vvnB-4tq5A:undetectable | 5vvnA-4tq5A:20.515vvnB-4tq5A:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3v | POLYKETIDE SYNTHASEPKSR (Bacillussubtilis) |
PF14765(PS-DH) | 4 | TRP A 140PHE A 144GLU A 139VAL A 19 | None | 1.06A | 5vvnA-4u3vA:undetectable5vvnB-4u3vA:undetectable | 5vvnA-4u3vA:19.475vvnB-4u3vA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udr | GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE (Methylovorussp. MP688) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | GLU A 306SER A 308VAL A 465TRP A 369 | None | 1.20A | 5vvnA-4udrA:undetectable5vvnB-4udrA:undetectable | 5vvnA-4udrA:23.945vvnB-4udrA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zhj | MG-CHELATASE SUBUNITCHLH (Synechocystissp. PCC 6803) |
PF02514(CobN-Mg_chel)PF11965(DUF3479) | 4 | TRP A 193PHE A 204SER A 86VAL A 113 | None | 1.37A | 5vvnA-4zhjA:undetectable5vvnB-4zhjA:undetectable | 5vvnA-4zhjA:14.985vvnB-4zhjA:14.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 4 | PHE A1476SER A1423VAL A1426TRP A1425 | None | 1.28A | 5vvnA-5a31A:undetectable5vvnB-5a31A:undetectable | 5vvnA-5a31A:15.285vvnB-5a31A:15.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cag | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF17145(DUF5119) | 4 | PHE A 220GLU A 156SER A 157VAL A 134 | None | 1.30A | 5vvnA-5cagA:undetectable5vvnB-5cagA:undetectable | 5vvnA-5cagA:20.085vvnB-5cagA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cow | PUTATIVEUNCHARACTERIZEDPROTEIN (Caenorhabditisremanei) |
no annotation | 4 | TRP A 407PHE A 404GLU A 410VAL A 409 | None | 1.33A | 5vvnA-5cowA:undetectable5vvnB-5cowA:undetectable | 5vvnA-5cowA:20.905vvnB-5cowA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csu | 4-ALPHA-GLUCANOTRANSFERASE DPE1,CHLOROPLASTIC/AMYLOPLASTIC (Arabidopsisthaliana) |
PF02446(Glyco_hydro_77) | 4 | TRP A 338SER A 324VAL A 384TRP A 382 | HMC A 606 ( 3.6A)NoneNoneNone | 1.37A | 5vvnA-5csuA:undetectable5vvnB-5csuA:undetectable | 5vvnA-5csuA:21.805vvnB-5csuA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gn5 | GLYCEROL KINASE (Trypanosomabrucei) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | TRP A 326PHE A 359GLU A 325VAL A 324 | None | 1.43A | 5vvnA-5gn5A:undetectable5vvnB-5gn5A:undetectable | 5vvnA-5gn5A:22.695vvnB-5gn5A:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gpl | PUTATIVE NUCLEOSOMEASSEMBLY PROTEINC36B7.08C (Schizosaccharomycespombe) |
PF00956(NAP) | 4 | PHE A 161GLU A 55SER A 70VAL A 51 | None | 1.42A | 5vvnA-5gplA:undetectable5vvnB-5gplA:undetectable | 5vvnA-5gplA:18.855vvnB-5gplA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6s | ENDOGLUCANASE (Talaromycesverruculosus) |
PF00150(Cellulase) | 4 | GLU A 148SER A 149VAL A 151ARG A 106 | None | 1.46A | 5vvnA-5i6sA:undetectable5vvnB-5i6sA:undetectable | 5vvnA-5i6sA:19.605vvnB-5i6sA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iwz | SYNAPTONEMAL COMPLEXPROTEIN 2 (Mus musculus) |
no annotation | 4 | TRP A 239PHE A 249GLU A 205SER A 201 | None | 1.15A | 5vvnA-5iwzA:undetectable5vvnB-5iwzA:undetectable | 5vvnA-5iwzA:20.875vvnB-5iwzA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jse | PHIAB6 TAILSPIKE (unidentifiedphage) |
PF12708(Pectate_lyase_3) | 4 | TRP A 347PHE A 290VAL A 341TRP A 323 | None | 1.12A | 5vvnA-5jseA:undetectable5vvnB-5jseA:undetectable | 5vvnA-5jseA:19.315vvnB-5jseA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jt4 | CYTOCHROME C' (Achromobacterxylosoxidans) |
PF01322(Cytochrom_C_2) | 4 | PHE A 79GLU A 71SER A 74TRP A 73 | HEC A 201 (-4.4A)NoneNoneNone | 1.22A | 5vvnA-5jt4A:undetectable5vvnB-5jt4A:undetectable | 5vvnA-5jt4A:14.385vvnB-5jt4A:14.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lcw | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 1 (Homo sapiens) |
PF12859(ANAPC1) | 4 | PHE A1476SER A1423VAL A1426TRP A1425 | None | 1.36A | 5vvnA-5lcwA:undetectable5vvnB-5lcwA:undetectable | 5vvnA-5lcwA:12.695vvnB-5lcwA:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lp8 | E3 UBIQUITIN-PROTEINLIGASE HUWE1 (Homo sapiens) |
no annotation | 4 | PHE B4109GLU B4033VAL B4019TRP B4065 | None | 1.25A | 5vvnA-5lp8B:undetectable5vvnB-5lp8B:undetectable | 5vvnA-5lp8B:21.315vvnB-5lp8B:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lsk | CENTROMERE PROTEIN CKINETOCHORE-ASSOCIATED PROTEIN NSL1HOMOLOG (Homo sapiens) |
PF08641(Mis14)PF15622(CENP_C_N) | 4 | PHE N 115GLU N 117VAL N 120ARG P 16 | None | 1.14A | 5vvnA-5lskN:undetectable5vvnB-5lskN:undetectable | 5vvnA-5lskN:19.095vvnB-5lskN:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8t | 5,6-DIHYDROXYINDOLE-2-CARBOXYLIC ACIDOXIDASE (Homo sapiens) |
PF00264(Tyrosinase) | 4 | TRP A 414PHE A 411GLU A 413ARG A 225 | None | 1.03A | 5vvnA-5m8tA:undetectable5vvnB-5m8tA:undetectable | 5vvnA-5m8tA:21.755vvnB-5m8tA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqz | PUTATIVEBRANCHED-CHAIN-AMINO-ACIDAMINOTRANSFERASE (Archaeoglobusfulgidus) |
no annotation | 4 | PHE A 43GLU A 282SER A 278ARG A 44 | None | 1.36A | 5vvnA-5mqzA:undetectable5vvnB-5mqzA:undetectable | 5vvnA-5mqzA:12.855vvnB-5mqzA:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n29 | CTP SYNTHASE (Trypanosomabrucei) |
PF00117(GATase) | 4 | PHE A 508GLU A 478SER A 519VAL A 477 | None | 1.38A | 5vvnA-5n29A:undetectable5vvnB-5n29A:undetectable | 5vvnA-5n29A:21.635vvnB-5n29A:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5no8 | BACCELL_00875 (Bacteroidescellulosilyticus) |
no annotation | 4 | TRP A 599PHE A 606VAL A 538ARG A 205 | None | 1.43A | 5vvnA-5no8A:undetectable5vvnB-5no8A:undetectable | 5vvnA-5no8A:21.875vvnB-5no8A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uv2 | (+)-LIMONENESYNTHASE (Citrus sinensis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 4 | PHE A 152GLU A 165SER A 168ARG A 156 | None | 1.29A | 5vvnA-5uv2A:undetectable5vvnB-5uv2A:undetectable | 5vvnA-5uv2A:22.415vvnB-5uv2A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vyo | THIOL:DISULFIDEINTERCHANGE PROTEIN (Burkholderiapseudomallei) |
no annotation | 4 | PHE A 49GLU A 54VAL A 57TRP A 56 | None | 1.05A | 5vvnA-5vyoA:undetectable5vvnB-5vyoA:undetectable | 5vvnA-5vyoA:9.715vvnB-5vyoA:9.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w62 | APOPTOSIS REGULATORBAX (Mus musculus) |
no annotation | 4 | PHE A 30GLU A 61SER A 62ARG A 34 | None | 1.19A | 5vvnA-5w62A:1.65vvnB-5w62A:undetectable | 5vvnA-5w62A:12.305vvnB-5w62A:12.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wb5 | PUTATIVE EUKARYOTICTRANSLATIONINITIATION FACTOREIF-4E (Leishmaniamajor) |
no annotation | 4 | PHE A 54GLU A 52SER A 49VAL A 47 | None | 1.02A | 5vvnA-5wb5A:undetectable5vvnB-5wb5A:undetectable | 5vvnA-5wb5A:12.065vvnB-5wb5A:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wly | UDP-2,3-DIACYLGLUCOSAMINE HYDROLASE (Escherichiacoli) |
no annotation | 4 | TRP A 219GLU A 222SER A 224ARG A 24 | None | 1.13A | 5vvnA-5wlyA:undetectable5vvnB-5wlyA:undetectable | 5vvnA-5wlyA:10.765vvnB-5wlyA:10.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x2o | TASTE RECEPTOR, TYPE1, MEMBER 3 (Oryzias latipes) |
PF01094(ANF_receptor) | 4 | TRP B 302PHE B 284SER B 299VAL B 272 | None | 1.43A | 5vvnA-5x2oB:undetectable5vvnB-5x2oB:undetectable | 5vvnA-5x2oB:20.665vvnB-5x2oB:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | 40S RIBOSOMALPROTEIN S5-B,PUTATIVEUNCHARACTERIZEDPROTEIN (Trichomonasvaginalis) |
PF00177(Ribosomal_S7)PF00333(Ribosomal_S5)PF03719(Ribosomal_S5_C) | 4 | PHE F 50GLU c 51VAL c 16ARG F 49 | NoneNoneNone C 21421 ( 4.4A) | 0.99A | 5vvnA-5xyiF:undetectable5vvnB-5xyiF:undetectable | 5vvnA-5xyiF:18.085vvnB-5xyiF:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6y | JC57-14 LIGHT CHAIN (Macaca mulatta) |
no annotation | 4 | PHE B 209GLU B 122SER B 121VAL B 125 | None | 1.40A | 5vvnA-6c6yB:undetectable5vvnB-6c6yB:undetectable | 5vvnA-6c6yB:15.115vvnB-6c6yB:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsa | - (-) |
no annotation | 4 | PHE E 359GLU E 229SER E 232ARG E 355 | None | 1.39A | 5vvnA-6gsaE:undetectable5vvnB-6gsaE:undetectable | 5vvnA-6gsaE:undetectable5vvnB-6gsaE:undetectable |