SIMILAR PATTERNS OF AMINO ACIDS FOR 5VUN_A_MTLA805_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de6 L-RHAMNOSE ISOMERASE

(Escherichia
coli) 		PF06134
(RhaA) 		4 ARG A 351
GLN A 393
ASN A 352
TRP A 392
 None
 1.33A 5vunA-1de6A:
0.0		 5vunA-1de6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ev1 ECHOVIRUS 1

(Enterovirus B) 		PF00073
(Rhv) 		4 SER 3  94
GLN 3  87
PHE 3  86
ASN 3  97
 None
 1.20A 5vunA-1ev13:
undetectable		 5vunA-1ev13:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 SER A 112
ARG A 212
GLN A 318
ASP A 218
 None
 1.23A 5vunA-1hn0A:
0.0		 5vunA-1hn0A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iw8 ACID PHOSPHATASE

(Shimwellia
blattae) 		PF01569
(PAP2) 		4 ASN A 211
GLN A 216
PHE A 214
ASN A 101
 None
 1.28A 5vunA-1iw8A:
0.0		 5vunA-1iw8A:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5c ENDOPOLYGALACTURONAS
E

(Chondrostereum
purpureum) 		PF00295
(Glyco_hydro_28) 		4 SER A 198
ASN A 179
GLN A 120
ASP A 173
 None
 1.24A 5vunA-1k5cA:
0.0		 5vunA-1k5cA:
18.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lzx NITRIC-OXIDE
SYNTHASE

(Rattus
norvegicus) 		PF02898
(NO_synthase) 		8 SER A 477
ARG A 481
ASN A 498
GLN A 500
PHE A 501
ASN A 569
ASP A 709
TRP A 711
 None
 0.31A 5vunA-1lzxA:
63.4		 5vunA-1lzxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		6 SER A 246
ARG A 250
ASN A 267
ASN A 338
ASP A 478
TRP A 480
 None
 0.39A 5vunA-1m9qA:
59.7		 5vunA-1m9qA:
64.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oul STRINGENT STARVATION
PROTEIN B HOMOLOG

(Haemophilus
influenzae) 		PF04386
(SspB) 		4 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 0.99A 5vunA-1oulA:
0.0		 5vunA-1oulA:
16.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		5 SER A 256
ARG A 260
PHE A 280
ASN A 348
TRP A 490
 None
 0.62A 5vunA-1qw5A:
58.1		 5vunA-1qw5A:
63.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 SER A 517
ASN A 373
GLN A 716
ASN A 521
 None
 1.30A 5vunA-1rrhA:
undetectable		 5vunA-1rrhA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1twb STRINGENT STARVATION
PROTEIN B HOMOLOG

(Haemophilus
influenzae) 		PF04386
(SspB) 		4 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 1.02A 5vunA-1twbA:
undetectable		 5vunA-1twbA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xr4 PUTATIVE CITRATE
LYASE ALPHA
CHAIN/CITRATE-ACP
TRANSFERASE

(Salmonella
enterica) 		PF04223
(CitF) 		4 SER A 297
ASN A 361
PHE A 268
ASP A 266
 None
 1.31A 5vunA-1xr4A:
undetectable		 5vunA-1xr4A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvl SIGNAL TRANSDUCER
AND ACTIVATOR OF
TRANSCRIPTION
1-ALPHA/BETA

(Homo sapiens) 		PF00017
(SH2)
PF01017
(STAT_alpha)
PF02864
(STAT_bind)
PF02865
(STAT_int) 		4 GLN A  95
PHE A  94
ASN A  89
ASP A  92
 None
 1.26A 5vunA-1yvlA:
undetectable		 5vunA-1yvlA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z3v CELLULASE

(Phanerochaete
chrysosporium) 		PF00840
(Glyco_hydro_7) 		4 SER A 321
GLN A 329
PHE A 326
ASN A 320
 None
 1.15A 5vunA-1z3vA:
undetectable		 5vunA-1z3vA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9v GMP SYNTHASE

(Thermoplasma
acidophilum) 		PF00117
(GATase) 		4 ASN A 128
GLN A 165
ASN A  54
ASP A 131
 None
 1.32A 5vunA-2a9vA:
undetectable		 5vunA-2a9vA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eid GALACTOSE OXIDASE

(Fusarium
graminearum) 		PF00754
(F5_F8_type_C)
PF01344
(Kelch_1)
PF09118
(DUF1929) 		4 ASN A  66
GLN A 526
PHE A 116
ASP A 524
 None
 1.22A 5vunA-2eidA:
undetectable		 5vunA-2eidA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5g PUTATIVE LIPOPROTEIN

(Campylobacter
jejuni) 		PF04187
(Cofac_haem_bdg) 		4 ASN X  62
GLN X  57
PHE X  61
ASN X 125
 None
 1.25A 5vunA-2g5gX:
undetectable		 5vunA-2g5gX:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv0 LYSOZYME C

(Pelodiscus
sinensis) 		PF00062
(Lys) 		4 SER A  62
GLN A  51
ASN A  61
ASP A  50
 None
 1.23A 5vunA-2gv0A:
undetectable		 5vunA-2gv0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 SER A 512
ASN A 368
GLN A 711
ASN A 516
 None
 1.25A 5vunA-2iujA:
undetectable		 5vunA-2iujA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k1g LIPOPROTEIN SPR

(Escherichia
coli) 		PF00877
(NLPC_P60) 		4 SER A  61
ARG A  86
GLN A  47
TRP A  51
 None
 1.33A 5vunA-2k1gA:
undetectable		 5vunA-2k1gA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kcy 30S RIBOSOMAL
PROTEIN S8E

(Methanothermobacter
thermautotrophicus) 		PF01201
(Ribosomal_S8e) 		4 SER A  75
ARG A  76
ASN A  84
ASP A  80
 None
 1.23A 5vunA-2kcyA:
undetectable		 5vunA-2kcyA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lbf 60S ACIDIC RIBOSOMAL
PROTEIN P2

(Homo sapiens) 		PF00428
(Ribosomal_60s) 		4 SER B 117
ASN B 147
ASN B 115
ASP B 122
 None
 1.05A 5vunA-2lbfB:
undetectable		 5vunA-2lbfB:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mpr MALTOPORIN

(Salmonella
enterica) 		PF02264
(LamB) 		4 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.29A 5vunA-2mprA:
undetectable		 5vunA-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2psb YERB PROTEIN

(Bacillus
subtilis) 		PF11258
(DUF3048)
PF17479
(DUF3048_C) 		4 SER A  93
PHE A  96
ASN A  94
ASP A  97
 None
 1.19A 5vunA-2psbA:
undetectable		 5vunA-2psbA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe9 UNCHARACTERIZED
PROTEIN YIZA

(Bacillus
subtilis) 		PF05163
(DinB) 		4 SER A  79
ARG A  12
PHE A  82
ASN A  80
 None
 1.25A 5vunA-2qe9A:
undetectable		 5vunA-2qe9A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qjv UNCHARACTERIZED
IOLB-LIKE PROTEIN

(Salmonella
enterica) 		PF04962
(KduI) 		4 ARG A 190
ASN A 217
GLN A 195
PHE A 191
 SO4  A 277 (-3.2A)
SO4  A 277 (-3.5A)
None
None
 0.90A 5vunA-2qjvA:
undetectable		 5vunA-2qjvA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4g TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		PF12009
(Telomerase_RBD) 		4 ASN A 317
GLN A 282
PHE A 318
ASN A 322
 None
 1.30A 5vunA-2r4gA:
undetectable		 5vunA-2r4gA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v3s SERINE/THREONINE-PRO
TEIN KINASE OSR1

(Homo sapiens) 		PF12202
(OSR1_C) 		4 ARG A 441
GLN A 523
ASN A 448
ASP A 449
 None
 1.33A 5vunA-2v3sA:
undetectable		 5vunA-2v3sA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brz TODX

(Pseudomonas
putida) 		PF03349
(Toluene_X) 		4 SER A 430
ARG A 391
ASN A 393
GLN A  83
 None
 1.23A 5vunA-3brzA:
undetectable		 5vunA-3brzA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3clw CONSERVED EXPORTED
PROTEIN

(Bacteroides
fragilis) 		PF14587
(Glyco_hydr_30_2) 		4 ARG A  52
GLN A 133
PHE A  55
ASN A 113
 None
 1.33A 5vunA-3clwA:
undetectable		 5vunA-3clwA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3da2 CARBONIC ANHYDRASE
13

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 SER A  66
ASN A  68
ASN A 245
TRP A   6
 None
 1.33A 5vunA-3da2A:
undetectable		 5vunA-3da2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dal PR DOMAIN ZINC
FINGER PROTEIN 1

(Homo sapiens) 		PF00856
(SET) 		4 ARG A  75
PHE A  76
ASN A  26
ASP A  27
 None
 1.24A 5vunA-3dalA:
undetectable		 5vunA-3dalA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkh LACCASE-1

(Melanocarpus
albomyces) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 SER A 135
ARG A 272
GLN A  99
TRP A 127
 None
 1.32A 5vunA-3dkhA:
undetectable		 5vunA-3dkhA:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 266
ASN A 283
PHE A 286
TRP A 496
 AT2  A 906 (-3.6A)
None
None
None
 1.02A 5vunA-3e7gA:
57.3		 5vunA-3e7gA:
65.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ASN A 283
PHE A 286
ASN A 354
TRP A 496
 None
 1.03A 5vunA-3e7gA:
57.3		 5vunA-3e7gA:
65.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goz LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN

(Legionella
pneumophila) 		no annotation 4 SER A 204
ARG A 175
ASN A 235
ASP A 261
 None
 1.07A 5vunA-3gozA:
undetectable		 5vunA-3gozA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihv SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASN A 384
GLN A 382
ASN A 523
TRP A 515
 None
 1.06A 5vunA-3ihvA:
undetectable		 5vunA-3ihvA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ij3 CYTOSOL
AMINOPEPTIDASE

(Coxiella
burnetii) 		PF00883
(Peptidase_M17) 		4 ARG A 122
ASN A 117
ASN A 154
ASP A 151
 None
 1.28A 5vunA-3ij3A:
undetectable		 5vunA-3ij3A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ij6 UNCHARACTERIZED
METAL-DEPENDENT
HYDROLASE

(Lactobacillus
acidophilus) 		PF04909
(Amidohydro_2) 		4 ASN A 281
GLN A 274
ASN A  53
ASP A  51
 None
 1.30A 5vunA-3ij6A:
undetectable		 5vunA-3ij6A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ix1 N-FORMYL-4-AMINO-5-A
MINOMETHYL-2-METHYLP
YRIMIDINE BINDING
PROTEIN

(Bacillus
halodurans) 		PF09084
(NMT1) 		4 SER A 109
ARG A 112
ASN A 289
PHE A 294
 None
 1.19A 5vunA-3ix1A:
undetectable		 5vunA-3ix1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kci PROBABLE E3
UBIQUITIN-PROTEIN
LIGASE HERC2

(Homo sapiens) 		PF00415
(RCC1) 		4 SER A4182
ARG A4238
GLN A4156
ASP A4171
 None
 1.19A 5vunA-3kciA:
undetectable		 5vunA-3kciA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kci PROBABLE E3
UBIQUITIN-PROTEIN
LIGASE HERC2

(Homo sapiens) 		PF00415
(RCC1) 		4 SER A4182
ARG A4238
GLN A4207
ASP A4171
 None
 1.24A 5vunA-3kciA:
undetectable		 5vunA-3kciA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kyd SUMO-ACTIVATING
ENZYME SUBUNIT 2

(Homo sapiens) 		PF00899
(ThiF)
PF14732
(UAE_UbL) 		4 ARG B  59
ASN B  56
GLN B 195
ASP B  53
 None
 1.25A 5vunA-3kydB:
undetectable		 5vunA-3kydB:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8h PUTATIVE HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bordetella
bronchiseptica) 		PF13242
(Hydrolase_like) 		4 SER A  16
GLN A  52
PHE A  19
ASP A   9
 None
PO4  A2001 ( 4.8A)
None
PO4  A2001 ( 4.3A)
 1.31A 5vunA-3l8hA:
undetectable		 5vunA-3l8hA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lrv PRE-MRNA-SPLICING
FACTOR 19

(Saccharomyces
cerevisiae) 		no annotation 4 ASN A 497
PHE A 496
ASN A 187
ASP A 494
 None
None
SO4  A  69 (-4.3A)
None
 1.29A 5vunA-3lrvA:
undetectable		 5vunA-3lrvA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o39 PERIPLASMIC PROTEIN
RELATED TO
SPHEROBLAST
FORMATION

(Escherichia
coli) 		PF07813
(LTXXQ) 		4 ASN A 116
GLN A 111
PHE A 115
ASN A 105
 None
 1.24A 5vunA-3o39A:
undetectable		 5vunA-3o39A:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pgl CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1

(Homo sapiens) 		PF03031
(NIF) 		4 SER A 208
ASN A 187
ASN A 207
ASP A  96
 None
None
MG  A   1 (-2.7A)
MG  A   1 (-2.5A)
 1.07A 5vunA-3pglA:
undetectable		 5vunA-3pglA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3to3 PETROBACTIN
BIOSYNTHESIS PROTEIN
ASBB

(Bacillus
anthracis) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 ASN A 175
GLN A 171
PHE A 170
ASN A 303
 None
 1.13A 5vunA-3to3A:
undetectable		 5vunA-3to3A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txa CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF00092
(VWA) 		4 SER A 555
ASN A 521
GLN A 357
PHE A 520
 None
 1.22A 5vunA-3txaA:
undetectable		 5vunA-3txaA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0k PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3-LIKE PROTEIN

(Chaetomium
thermophilum) 		no annotation 4 SER B 538
ARG B 540
GLN B 484
ASN B 523
 None
 1.18A 5vunA-4d0kB:
undetectable		 5vunA-4d0kB:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f92 U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 ASN B 912
GLN B 980
PHE B 979
ASP B 973
 None
 1.09A 5vunA-4f92B:
undetectable		 5vunA-4f92B:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fn5 ELONGATION FACTOR G
1

(Pseudomonas
aeruginosa) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF03764
(EFG_IV)
PF14492
(EFG_II) 		4 ARG A  29
ASN A 272
ASN A 142
ASP A 145
 None
 1.27A 5vunA-4fn5A:
undetectable		 5vunA-4fn5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fva 5'-TYROSYL-DNA
PHOSPHODIESTERASE

(Caenorhabditis
elegans) 		PF03372
(Exo_endo_phos) 		4 SER A 280
ARG A 281
GLN A 246
PHE A 247
 None
 1.29A 5vunA-4fvaA:
undetectable		 5vunA-4fvaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdz UNCHARACTERIZED
PROTEIN

(Bacteroides
eggerthii) 		PF14059
(DUF4251) 		4 SER A 181
ASN A  73
ASN A 161
ASP A 160
 None
 1.30A 5vunA-4gdzA:
undetectable		 5vunA-4gdzA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr6 ATRBCX2

(Arabidopsis
thaliana) 		PF02341
(RcbX) 		4 ARG A  80
PHE A  61
ASN A  21
ASP A  57
 None
 1.23A 5vunA-4gr6A:
undetectable		 5vunA-4gr6A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594

(Pyrococcus
horikoshii) 		PF00326
(Peptidase_S9)
PF07676
(PD40) 		4 SER B  62
GLN B  86
ASN B  43
ASP B  60
 None
 1.26A 5vunA-4hxeB:
undetectable		 5vunA-4hxeB:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ine PROTEIN PMT-2

(Caenorhabditis
elegans) 		PF08241
(Methyltransf_11) 		4 SER A 257
ARG A 179
GLN A 115
ASN A 258
 None
 1.12A 5vunA-4ineA:
undetectable		 5vunA-4ineA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irx SUGAR ABC
TRANSPORTER,
PERIPLASMIC
SUGAR-BINDING
PROTEIN

(Caulobacter
vibrioides) 		PF13407
(Peripla_BP_4) 		4 ASN A 231
GLN A 278
ASN A  45
ASP A 125
 INS  A 401 (-3.9A)
INS  A 401 (-3.1A)
None
INS  A 401 (-2.8A)
 1.26A 5vunA-4irxA:
undetectable		 5vunA-4irxA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m00 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		PF05345
(He_PIG) 		4 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
SUC  A 804 (-3.3A)
 1.27A 5vunA-4m00A:
undetectable		 5vunA-4m00A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m01 SERINE-RICH ADHESIN
FOR PLATELETS

(Staphylococcus
aureus) 		no annotation 4 ASN A 275
GLN A 482
ASN A 347
ASP A 330
 None
None
None
GOL  A 602 (-3.3A)
 1.26A 5vunA-4m01A:
undetectable		 5vunA-4m01A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oi3 NICKEL RESPONSIVE
PROTEIN

(Streptomyces
coelicolor) 		PF14026
(DUF4242) 		4 SER A  53
GLN A  62
PHE A   4
ASP A   6
 None
 1.30A 5vunA-4oi3A:
undetectable		 5vunA-4oi3A:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pl0 MICROCIN-J25 EXPORT
ATP-BINDING/PERMEASE
PROTEIN MCJD

(Escherichia
coli) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		4 ARG A 141
ASN A 142
ASN A 134
ASP A 135
 None
 1.32A 5vunA-4pl0A:
undetectable		 5vunA-4pl0A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvi GH62 HYDROLASE

(Mycothermus
thermophilus) 		PF03664
(Glyco_hydro_62) 		4 ASN A  -6
GLN A  -2
PHE A  -3
TRP A  32
 None
 1.28A 5vunA-4pviA:
undetectable		 5vunA-4pviA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uac CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-)

([Eubacterium]
rectale) 		PF13416
(SBP_bac_8) 		4 GLN A 394
PHE A 189
ASN A 191
ASP A 190
 EDO  A 504 (-3.3A)
None
ACR  A 501 (-3.3A)
EDO  A 504 ( 4.2A)
 1.13A 5vunA-4uacA:
undetectable		 5vunA-4uacA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ync NADPH DEHYDROGENASE
1

(Saccharomyces
pastorianus) 		PF00724
(Oxidored_FMN) 		4 ASN A 207
GLN A 200
ASN A 140
TRP A 120
 None
 1.32A 5vunA-4yncA:
undetectable		 5vunA-4yncA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z9p NUCLEOPROTEIN

(Zaire
ebolavirus) 		PF05505
(Ebola_NP) 		4 SER A 279
GLN A 315
PHE A 313
ASN A 278
 None
 1.30A 5vunA-4z9pA:
undetectable		 5vunA-4z9pA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a53 REGULATOR OF
RIBOSOME
BIOSYNTHESIS
RIBOSOME BIOGENESIS
PROTEIN RPF2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04939
(RRS1)
PF04427
(Brix) 		4 SER C 169
ARG C 166
ASN A  25
ASP C 171
 SO4  C1254 (-3.2A)
SO4  C1254 (-3.1A)
None
None
 1.04A 5vunA-5a53C:
undetectable		 5vunA-5a53C:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aex AMMONIUM TRANSPORTER
MEP2

(Saccharomyces
cerevisiae) 		PF00909
(Ammonium_transp) 		4 SER A 116
ASN A 174
PHE A  89
ASP A 122
 None
 1.10A 5vunA-5aexA:
undetectable		 5vunA-5aexA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnz GLUTAMINE--TRNA
LIGASE

(Pseudomonas
aeruginosa) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 GLN A 202
PHE A  67
ASN A  38
ASP A  76
 None
 1.22A 5vunA-5bnzA:
undetectable		 5vunA-5bnzA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d6a PREDICTED ATPASE OF
THE ABC CLASS

(Vibrio
vulnificus) 		PF09818
(ABC_ATPase) 		4 SER A 457
ARG A 455
ASN A 486
ASP A 526
 None
 1.31A 5vunA-5d6aA:
undetectable		 5vunA-5d6aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dku PREX DNA POLYMERASE

(Plasmodium
falciparum) 		PF00476
(DNA_pol_A)
PF01612
(DNA_pol_A_exo1) 		4 SER A 202
ASN A 114
PHE A 113
ASN A 201
 None
 1.15A 5vunA-5dkuA:
undetectable		 5vunA-5dkuA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5du3 PLASMA PROTEASE C1
INHIBITOR

(Homo sapiens) 		PF00079
(Serpin) 		4 SER A 198
ASN A 269
GLN A 201
TRP A 243
 None
 1.26A 5vunA-5du3A:
undetectable		 5vunA-5du3A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eqn FRBJ

(Streptomyces
rubellomurinus) 		PF02668
(TauD) 		4 ARG A 203
GLN A 115
ASP A 152
TRP A 311
 None
None
MG  A 401 (-3.5A)
None
 1.08A 5vunA-5eqnA:
undetectable		 5vunA-5eqnA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gr1 1,4-ALPHA-GLUCAN
BRANCHING ENZYME
GLGB

(Cyanothece sp.
ATCC 51142) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		4 SER A 709
GLN A 625
PHE A 629
ASN A 708
 None
GOL  A 824 (-4.4A)
None
GLC  A 815 ( 4.1A)
 1.24A 5vunA-5gr1A:
undetectable		 5vunA-5gr1A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5haf DEUBIQUITINASE SSEL

(Salmonella
enterica) 		no annotation 4 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.33A 5vunA-5hafA:
undetectable		 5vunA-5hafA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Homo sapiens;
Dictyostelium
discoideum) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		4 GLN A 583
PHE A 594
ASN A 488
ASP A 604
 None
 1.31A 5vunA-5i4eA:
undetectable		 5vunA-5i4eA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 SER A 663
GLN B1065
PHE B1086
ASN A 742
 None
 1.32A 5vunA-5ip9A:
undetectable		 5vunA-5ip9A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jm0 ALPHA-MANNOSIDASE,AL
PHA-MANNOSIDASE,ALPH
A-MANNOSIDASE

(Saccharomyces
cerevisiae) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C)
PF09261
(Alpha-mann_mid) 		4 GLN A 130
PHE A 198
ASN A 195
ASP A 132
 None
 1.31A 5vunA-5jm0A:
undetectable		 5vunA-5jm0A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lii MAJOR CAPSID PROTEIN

(Staphylococcus
phage 812) 		no annotation 4 ASN P 247
GLN P 237
ASN P 242
ASP P 241
 None
 1.26A 5vunA-5liiP:
undetectable		 5vunA-5liiP:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 SER A 149
ARG A 290
GLN A 114
TRP A 141
 None
 1.33A 5vunA-5lm8A:
undetectable		 5vunA-5lm8A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m8j DIVALENT METAL
CATION TRANSPORTER
MNTH

(Eremococcus
coleocola) 		PF01566
(Nramp) 		4 SER A 343
GLN A 407
ASN A 342
ASP A  51
 None
 1.24A 5vunA-5m8jA:
undetectable		 5vunA-5m8jA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqr CONDENSIN COMPLEX
SUBUNIT 3

(Schizosaccharomyces
pombe) 		no annotation 4 SER A 188
ARG A 160
PHE A 192
ASN A 187
 None
 1.32A 5vunA-5oqrA:
undetectable		 5vunA-5oqrA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t1q N-ACETYLMURAMOYL-L-A
LANINE AMIDASE
DOMAIN-CONTAINING
PROTEIN
SAOUHSC_02979

(Staphylococcus
aureus) 		PF01832
(Glucosaminidase)
PF05257
(CHAP) 		4 ASN A 283
PHE A 282
ASN A 383
ASP A 290
 None
 1.24A 5vunA-5t1qA:
undetectable		 5vunA-5t1qA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tr0 SEED LINOLEATE
13S-LIPOXYGENASE-1

(Glycine max) 		no annotation 4 SER A 498
ASN A 355
GLN A 697
ASN A 502
 None
 1.27A 5vunA-5tr0A:
undetectable		 5vunA-5tr0A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubk ACYL-HOMOSERINE
LACTONE ACYLASE PVDQ

(Pseudomonas
aeruginosa) 		PF01804
(Penicil_amidase) 		4 SER A 303
ARG A 304
GLN A 401
ASP A 398
 None
 1.28A 5vunA-5ubkA:
undetectable		 5vunA-5ubkA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubw DEUBIQUITINASE SSEL

(Salmonella
enterica) 		no annotation 4 ARG A 331
ASN A 327
GLN A 323
PHE A 326
 None
 1.25A 5vunA-5ubwA:
undetectable		 5vunA-5ubwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vgb CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
ANTI-CRISPR PROTEIN
(ACRIIC1)

(Neisseria
meningitidis;
Neisseria
meningitidis) 		PF13395
(HNH_4)
no annotation 		4 ASN A  88
PHE A  87
ASN A  13
ASP B  44
 SO4  A 203 (-3.9A)
None
None
None
 1.15A 5vunA-5vgbA:
undetectable		 5vunA-5vgbA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vxz TYROSINE-PROTEIN
KINASE RECEPTOR UFO

(Homo sapiens) 		PF13927
(Ig_3) 		4 SER C  28
ASN C  33
GLN C  50
PHE C  30
 None
 1.23A 5vunA-5vxzC:
undetectable		 5vunA-5vxzC:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w3f TUBULIN ALPHA-1
CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		4 SER A 224
GLN A  15
PHE A 225
ASN A 227
 None
None
GTP  A 502 (-3.8A)
None
 1.18A 5vunA-5w3fA:
undetectable		 5vunA-5w3fA:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wql TAIL-SPECIFIC
PROTEASE

(Escherichia
coli) 		no annotation 4 SER C 503
ASN C 238
GLN C 236
PHE C 237
 None
 1.13A 5vunA-5wqlC:
undetectable		 5vunA-5wqlC:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xg8 GALACTOSIDE-BINDING
SOLUBLE LECTIN 13

(Homo sapiens) 		no annotation 4 SER A  29
PHE A  30
ASN A  32
ASP A  33
 None
 1.32A 5vunA-5xg8A:
undetectable		 5vunA-5xg8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjg VACUOLAR PROTEIN 8
NUCLEUS-VACUOLE
JUNCTION PROTEIN 1

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00514
(Arm)
no annotation 		4 SER A 280
ARG A 242
GLN B 308
ASN B 304
 None
 0.89A 5vunA-5xjgA:
undetectable		 5vunA-5xjgA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE
SUBUNIT ABC10-ALPHA

(Komagataella
phaffii;
Komagataella
phaffii) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF03604
(DNA_RNApol_7kD) 		4 ARG B 904
GLN L  68
PHE L  69
ASP L  70
 None
 1.32A 5vunA-5xogB:
undetectable		 5vunA-5xogB:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Komagataella
phaffii;
Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4)
PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 SER A 664
GLN B1065
PHE B1086
ASN A 743
 None
 1.31A 5vunA-5xogA:
undetectable		 5vunA-5xogA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
PERMEAE

(Streptococcus
pneumoniae) 		no annotation 4 ARG M 240
ASN M  56
GLN M  54
ASN M 242
 None
 1.13A 5vunA-5xu1M:
undetectable		 5vunA-5xu1M:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yem CATALASE

(Mycothermus
thermophilus) 		no annotation 4 ARG A 482
ASN A 479
GLN A 474
ASP A 507
 None
 1.23A 5vunA-5yemA:
undetectable		 5vunA-5yemA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yh5 NICKEL ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Staphylococcus
aureus) 		no annotation 4 ASN A 450
GLN A 130
ASN A 310
ASP A 308
 None
 1.21A 5vunA-5yh5A:
undetectable		 5vunA-5yh5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7k ENDO-ALPHA-(1->5)-L-
ARABINANASE

(Bacillus
licheniformis) 		no annotation 4 SER A 120
ASN A 127
GLN A 125
PHE A 126
 None
 1.29A 5vunA-6b7kA:
undetectable		 5vunA-6b7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d3i -

(-) 		no annotation 4 GLN A  53
PHE A 140
ASN A 265
ASP A 264
 None
 1.33A 5vunA-6d3iA:
undetectable		 5vunA-6d3iA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae) 		no annotation 4 SER A 507
ASN A 581
ASN A 508
ASP A 467
 None
 1.28A 5vunA-6fikA:
undetectable		 5vunA-6fikA:
undetectable