SIMILAR PATTERNS OF AMINO ACIDS FOR 5VLM_G_CVIG301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cb8 PROTEIN
(CHONDROITINASE AC)

(Pedobacter
heparinus) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 GLY A 411
TRP A 462
ASP A 385
TYR A 382
 None
 1.22A 5vlmG-1cb8A:
2.7		 5vlmG-1cb8A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1esc ESTERASE

(Streptomyces
scabiei) 		PF13472
(Lipase_GDSL_2) 		4 GLY A 109
GLN A  88
ASP A  13
TYR A  15
 None
 1.16A 5vlmG-1escA:
undetectable		 5vlmG-1escA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1guq GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE

(Escherichia
coli) 		PF01087
(GalP_UDP_transf)
PF02744
(GalP_UDP_tr_C) 		4 GLY A 159
TRP A 170
GLN A 149
TYR A 276
 UPG  A 352 (-3.8A)
UPG  A 352 ( 4.9A)
None
None
 1.27A 5vlmG-1guqA:
undetectable		 5vlmG-1guqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg2 CLATHRIN ASSEMBLY
PROTEIN SHORT FORM

(Rattus
norvegicus) 		PF07651
(ANTH) 		4 GLY A  89
GLN A 174
TYR A 130
ASP A 144
 None
 1.18A 5vlmG-1hg2A:
3.1		 5vlmG-1hg2A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hx8 SYNAPSE-ENRICHED
CLATHRIN ADAPTOR
PROTEIN LAP

(Drosophila
melanogaster) 		PF07651
(ANTH) 		4 GLY A  91
GLN A 188
TYR A 143
ASP A 157
 None
 1.17A 5vlmG-1hx8A:
1.2		 5vlmG-1hx8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k8q TRIACYLGLYCEROL
LIPASE, GASTRIC

(Canis lupus) 		PF00561
(Abhydrolase_1) 		4 GLN A  64
TYR A 149
ASP A 130
TYR A  38
 None
 1.29A 5vlmG-1k8qA:
undetectable		 5vlmG-1k8qA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2p CASEIN KINASE II,
ALPHA CHAIN

(Zea mays) 		PF00069
(Pkinase) 		4 GLY A 185
TYR A 257
ASP A 210
TYR A 211
 None
 1.19A 5vlmG-1m2pA:
0.2		 5vlmG-1m2pA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6

(Saccharopolyspora
erythraea) 		PF00975
(Thioesterase) 		4 GLY A 144
TRP A 246
ASP A 169
TYR A 171
 None
 1.20A 5vlmG-1mo2A:
0.4		 5vlmG-1mo2A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqs SLY1 PROTEIN

(Saccharomyces
cerevisiae) 		PF00995
(Sec1) 		4 GLY A 232
GLN A 601
TYR A 603
ASP A 586
 None
 0.86A 5vlmG-1mqsA:
2.4		 5vlmG-1mqsA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7r HYALURONIDASE

(Streptococcus
pneumoniae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 GLY A 619
TRP A 670
ASP A 591
TYR A 588
 None
 1.26A 5vlmG-1n7rA:
3.2		 5vlmG-1n7rA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qwy PEPTIDOGLYCAN
HYDROLASE

(Staphylococcus
aureus) 		PF01551
(Peptidase_M23) 		4 GLY A 285
GLN A 295
ASP A 119
TYR A 239
 None
 1.04A 5vlmG-1qwyA:
undetectable		 5vlmG-1qwyA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4f RNA-DEPENDENT RNA
POLYMERASE

(Pestivirus A) 		PF00998
(RdRP_3) 		4 GLY A 404
GLN A 308
TYR A 316
ASP A 409
 None
 1.29A 5vlmG-1s4fA:
undetectable		 5vlmG-1s4fA:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wd3 ALPHA-L-ARABINOFURAN
OSIDASE B

(Aspergillus
kawachii) 		PF05270
(AbfB)
PF09206
(ArabFuran-catal) 		4 GLY A 169
TRP A 454
GLN A 400
TYR A 333
 None
 1.17A 5vlmG-1wd3A:
undetectable		 5vlmG-1wd3A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 GLY A 174
TRP A 465
GLN A 464
TYR A 469
 None
 1.22A 5vlmG-1wz2A:
2.3		 5vlmG-1wz2A:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xio ANABAENA SENSORY
RHODOPSIN

(Nostoc sp. PCC
7120) 		PF01036
(Bac_rhodopsin) 		4 GLY A 191
TRP A 183
TYR A  73
ASP A 198
 None
RET  A 301 (-3.8A)
None
None
 1.20A 5vlmG-1xioA:
undetectable		 5vlmG-1xioA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j2m CATALASE

(Exiguobacterium
oxidotolerans) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 GLY A 122
GLN A 343
TYR A 351
ASP A 125
 None
HEM  A 501 (-3.9A)
None
None
 1.05A 5vlmG-2j2mA:
undetectable		 5vlmG-2j2mA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jc4 EXODEOXYRIBONUCLEASE
III

(Neisseria
meningitidis) 		PF03372
(Exo_endo_phos) 		4 GLY A 145
TRP A 123
GLN A  88
TYR A 119
 None
None
2HP  A1261 ( 3.9A)
None
 1.18A 5vlmG-2jc4A:
undetectable		 5vlmG-2jc4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jcj N-ACETYLLACTOSAMINID
E
ALPHA-1,3-GALACTOSYL
TRANSFERASE

(Bos taurus) 		PF03414
(Glyco_transf_6) 		4 GLY A 286
GLN A 125
TYR A 121
ASP A 219
 None
 1.13A 5vlmG-2jcjA:
undetectable		 5vlmG-2jcjA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jir PERIPLASMIC NITRATE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF04879
(Molybdop_Fe4S4) 		4 GLY A 351
TYR A 565
TRP A 551
ASP A 155
 None
 1.24A 5vlmG-2jirA:
undetectable		 5vlmG-2jirA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lgh UNCHARACTERIZED
PROTEIN

(Aeromonas
hydrophila) 		PF08327
(AHSA1) 		4 GLY A  68
TRP A 121
GLN A 117
ASP A  85
 None
 0.98A 5vlmG-2lghA:
undetectable		 5vlmG-2lghA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o57 PUTATIVE SARCOSINE
DIMETHYLGLYCINE
METHYLTRANSFERASE

(Galdieria
sulphuraria) 		PF08241
(Methyltransf_11) 		4 GLN A 117
TYR A  93
ASP A  30
TYR A  27
 None
 1.26A 5vlmG-2o57A:
undetectable		 5vlmG-2o57A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v40 ADENYLOSUCCINATE
SYNTHETASE ISOZYME 2

(Homo sapiens) 		PF00709
(Adenylsucc_synt) 		4 GLY A 178
GLN A 147
TYR A 206
TYR A 170
 None
 0.78A 5vlmG-2v40A:
undetectable		 5vlmG-2v40A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w38 SIALIDASE

(Pseudomonas
aeruginosa) 		PF13088
(BNR_2) 		4 GLY A  25
TRP A  63
ASP A  22
TYR A  21
 None
 1.16A 5vlmG-2w38A:
undetectable		 5vlmG-2w38A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yia RNA-DIRECTED RNA
POLYMERASE

(Infectious
pancreatic
necrosis virus) 		PF04197
(Birna_RdRp) 		4 GLY A 470
GLN A 413
ASP A 454
TYR A 467
 None
 1.28A 5vlmG-2yiaA:
1.4		 5vlmG-2yiaA:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yib RNA-DIRECTED RNA
POLYMERASE

(Infectious
pancreatic
necrosis virus) 		PF04197
(Birna_RdRp) 		4 GLY D 470
GLN D 413
ASP D 454
TYR D 467
 None
 1.28A 5vlmG-2yibD:
1.6		 5vlmG-2yibD:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zym SOLUTE-BINDING
PROTEIN

(Thermoactinomyces
vulgaris) 		PF13416
(SBP_bac_8) 		4 GLY A  72
TRP A  24
ASP A  76
TYR A 292
 None
 1.06A 5vlmG-2zymA:
undetectable		 5vlmG-2zymA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b1e BETAC-S LYASE

(Streptococcus
anginosus) 		PF00155
(Aminotran_1_2) 		4 GLY A 174
TYR A 164
TRP A 177
TYR A 356
 None
 1.23A 5vlmG-3b1eA:
undetectable		 5vlmG-3b1eA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3csk PROBABLE
DIPEPTIDYL-PEPTIDASE
3

(Saccharomyces
cerevisiae) 		PF03571
(Peptidase_M49) 		4 GLY A 538
TYR A  21
ASP A 451
TYR A 448
 None
 0.89A 5vlmG-3cskA:
undetectable		 5vlmG-3cskA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ctt MALTASE-GLUCOAMYLASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 GLY A 602
TRP A 406
ASP A 329
TYR A 301
 None
 1.17A 5vlmG-3cttA:
undetectable		 5vlmG-3cttA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cyv UROPORPHYRINOGEN
DECARBOXYLASE

(Shigella
flexneri) 		PF01208
(URO-D) 		4 GLY A 251
TRP A 210
TYR A 154
ASP A 208
 None
 1.15A 5vlmG-3cyvA:
undetectable		 5vlmG-3cyvA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d1c FLAVIN-CONTAINING
PUTATIVE
MONOOXYGENASE

(Staphylococcus
aureus) 		PF13738
(Pyr_redox_3) 		4 TRP A  45
TYR A 141
ASP A 179
TYR A 182
 FAD  A 500 (-4.1A)
FAD  A 500 (-4.7A)
None
None
 1.10A 5vlmG-3d1cA:
undetectable		 5vlmG-3d1cA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3go4 PROTEIN OF UNKNOWN
FUNCTION DUF574

(Streptomyces
avermitilis) 		PF04672
(Methyltransf_19) 		4 GLY A  33
TYR A 216
ASP A  40
TYR A  37
 SO4  A 278 (-3.1A)
None
None
None
 1.14A 5vlmG-3go4A:
undetectable		 5vlmG-3go4A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN

(Burkholderia
mallei) 		PF13458
(Peripla_BP_6) 		4 GLN A 303
TYR A 291
TRP A 371
ASP A  42
 None
None
EDO  A  11 (-4.5A)
EDO  A   8 (-4.4A)
 1.13A 5vlmG-3i09A:
undetectable		 5vlmG-3i09A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icq EXPORTIN-T

(Schizosaccharomyces
pombe) 		PF08389
(Xpo1) 		4 GLN T 132
TYR T 147
TRP T 218
ASP T 184
 None
 1.03A 5vlmG-3icqT:
3.0		 5vlmG-3icqT:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k32 UNCHARACTERIZED
PROTEIN MJ0690

(Methanocaldococcus
jannaschii) 		no annotation 4 GLY A 105
GLN A 190
ASP A 165
TYR A 166
 None
 1.24A 5vlmG-3k32A:
undetectable		 5vlmG-3k32A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l22 SUSD SUPERFAMILY
PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 GLY A 426
TYR A 152
ASP A 421
TYR A 405
 None
None
EDO  A  22 (-3.7A)
None
 1.24A 5vlmG-3l22A:
undetectable		 5vlmG-3l22A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l7v PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1377C

(Streptococcus
mutans) 		PF01300
(Sua5_yciO_yrdC) 		4 GLY A  59
TRP A  99
TYR A 104
ASP A 120
 None
 1.25A 5vlmG-3l7vA:
undetectable		 5vlmG-3l7vA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3luz EXTRAGENIC
SUPPRESSOR PROTEIN
SUHB

(Bartonella
henselae) 		PF00459
(Inositol_P) 		4 GLY A  90
TYR A 170
ASP A 193
TYR A 196
 None
 1.08A 5vlmG-3luzA:
undetectable		 5vlmG-3luzA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3men ACETYLPOLYAMINE
AMINOHYDROLASE

(Burkholderia
pseudomallei) 		PF00850
(Hist_deacetyl) 		4 GLY A 279
GLN A  27
ASP A 286
TYR A 283
 None
 1.28A 5vlmG-3menA:
undetectable		 5vlmG-3menA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqq PUTATIVE LIPOPROTEIN

(Bacteroides
ovatus) 		PF16129
(DUF4841)
PF16130
(DUF4842) 		4 GLY A 148
TRP A 456
TYR A 455
ASP A 202
 None
 1.29A 5vlmG-3oqqA:
undetectable		 5vlmG-3oqqA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0m LLAMA VHH A12

(Lama glama) 		PF07686
(V-set) 		4 GLY A  35
GLN A   3
ASP A 102
TYR A 101
 None
 1.00A 5vlmG-3r0mA:
undetectable		 5vlmG-3r0mA:
26.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rbt GLUTATHIONE
TRANSFERASE O1

(Bombyx mori) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 TRP A 204
GLN A 207
TYR A 160
TRP A 174
 None
 1.17A 5vlmG-3rbtA:
undetectable		 5vlmG-3rbtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rbt GLUTATHIONE
TRANSFERASE O1

(Bombyx mori) 		PF13410
(GST_C_2)
PF13417
(GST_N_3) 		4 TRP A 204
TYR A 160
TRP A 174
ASP A 206
 None
 1.10A 5vlmG-3rbtA:
undetectable		 5vlmG-3rbtA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rgw MEMBRANE-BOUND
HYDROGENASE (NIFE)
LARGE SUBUNIT HOXG

(Cupriavidus
necator) 		PF00374
(NiFeSe_Hases) 		4 GLY L 284
GLN L 148
ASP L 279
TYR L 276
 None
 1.20A 5vlmG-3rgwL:
1.2		 5vlmG-3rgwL:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5c LINA

(uncultured
organism) 		no annotation 4 GLY B  98
GLN B  20
TYR B 113
ASP B  25
 None
 1.13A 5vlmG-3s5cB:
undetectable		 5vlmG-3s5cB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5q CHI1

(Yersinia
entomophaga) 		PF00704
(Glyco_hydro_18) 		4 GLY A 119
TRP A  77
GLN A  79
ASP A 159
 None
 1.27A 5vlmG-4a5qA:
undetectable		 5vlmG-4a5qA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2n 70 KDA PROTEIN

(Xanthomonas sp.
35Y) 		no annotation 4 TRP A 525
TRP A 653
ASP A 561
TYR A 560
 None
 1.29A 5vlmG-4b2nA:
undetectable		 5vlmG-4b2nA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b7g CATALASE

(Corynebacterium
glutamicum) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 GLY A 136
GLN A 357
TYR A 365
ASP A 139
 None
HEM  A3000 (-3.7A)
None
None
 0.94A 5vlmG-4b7gA:
undetectable		 5vlmG-4b7gA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cab CATALASE

(Deinococcus
radiodurans) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 GLY A 152
GLN A 373
TYR A 381
ASP A 155
 None
HEM  A 537 (-4.3A)
None
None
 1.02A 5vlmG-4cabA:
undetectable		 5vlmG-4cabA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cot EXTRACELLULAR
ENDO-ALPHA-(1->5)-L-
ARABINANASE 2

(Bacillus
subtilis) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		4 GLY A 217
GLN A 318
TYR A 252
TYR A 186
 None
NI  A1470 ( 2.6A)
None
None
 1.05A 5vlmG-4cotA:
undetectable		 5vlmG-4cotA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hoo LYSINE-SPECIFIC
DEMETHYLASE 4D

(Homo sapiens) 		PF02373
(JmjC)
PF02375
(JmjN) 		4 GLY A 220
GLN A 309
ASP A 197
TYR A 303
 None
 1.29A 5vlmG-4hooA:
undetectable		 5vlmG-4hooA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4x AMPHI

(Streptomyces
nodosus) 		PF08659
(KR) 		4 GLY A 240
GLN A 247
TRP A 178
ASP A 245
 None
 1.20A 5vlmG-4l4xA:
undetectable		 5vlmG-4l4xA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4md8 CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLY E 185
TYR E 257
ASP E 210
TYR E 211
 None
 1.20A 5vlmG-4md8E:
undetectable		 5vlmG-4md8E:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ovj EXTRACELLULAR
SOLUTE-BINDING
PROTEIN FAMILY 1

(Alicyclobacillus
acidocaldarius) 		PF13416
(SBP_bac_8) 		4 GLY A 251
GLN A 412
TYR A 416
ASP A 204
 None
 1.15A 5vlmG-4ovjA:
undetectable		 5vlmG-4ovjA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p48 ANTIBODY SCFV 180

(Gallus gallus) 		PF07686
(V-set) 		4 GLY A  23
GLN A 163
ASP A 237
TYR A  32
 None
 1.24A 5vlmG-4p48A:
undetectable		 5vlmG-4p48A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qor CATALASE

(Bacillus
pumilus) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 GLY A 123
GLN A 344
TYR A 352
ASP A 126
 None
HEM  A 502 ( 3.7A)
None
None
 0.92A 5vlmG-4qorA:
undetectable		 5vlmG-4qorA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rhb LPS-ASSEMBLY PROTEIN
LPTD

(Escherichia
coli) 		PF04453
(OstA_C) 		4 GLY A 591
GLN A 460
TYR A 528
ASP A 524
 None
 0.99A 5vlmG-4rhbA:
undetectable		 5vlmG-4rhbA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Pisum sativum) 		PF00223
(PsaA_PsaB) 		4 GLY A 285
GLN A 231
TYR A 259
ASP A 288
 CLA  A1116 (-3.4A)
None
None
None
 1.12A 5vlmG-4rkuA:
undetectable		 5vlmG-4rkuA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rku PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1

(Pisum sativum) 		PF00223
(PsaA_PsaB) 		4 GLY A 286
GLN A 231
TYR A 259
ASP A 288
 None
 1.11A 5vlmG-4rkuA:
undetectable		 5vlmG-4rkuA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3p 4-ALPHA-GLUCANOTRANS
FERASE

(Escherichia
coli) 		PF02446
(Glyco_hydro_77) 		4 GLY A 651
GLN A 149
TYR A 151
ASP A 548
 None
 1.00A 5vlmG-4s3pA:
undetectable		 5vlmG-4s3pA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsh UROPORPHYRINOGEN
DECARBOXYLASE

(Pseudomonas
aeruginosa) 		PF01208
(URO-D) 		4 GLY A 252
TRP A 211
TYR A 155
ASP A 209
 None
 1.26A 5vlmG-4wshA:
undetectable		 5vlmG-4wshA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zr8 UROPORPHYRINOGEN
DECARBOXYLASE

(Acinetobacter
baumannii) 		PF01208
(URO-D) 		4 GLY A 251
TRP A 210
TYR A 154
ASP A 208
 None
 1.29A 5vlmG-4zr8A:
undetectable		 5vlmG-4zr8A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bxp LACTO-N-BIOSIDASE

(Bifidobacterium
bifidum) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b)
PF14200
(RicinB_lectin_2) 		4 GLY A 318
TRP A 465
GLN A 416
TYR A 427
 None
LOG  A 702 (-3.8A)
None
LOG  A 702 (-4.5A)
 1.21A 5vlmG-5bxpA:
undetectable		 5vlmG-5bxpA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT

(Candidatus
Kuenenia
stuttgartiensis) 		no annotation 4 GLY A 383
TRP A 335
GLN A  74
ASP A  71
 None
 1.15A 5vlmG-5c2vA:
undetectable		 5vlmG-5c2vA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cax GLUTAREDOXIN

(Methanosarcina
acetivorans) 		PF00462
(Glutaredoxin) 		4 GLY A  20
GLN A  66
TYR A  25
ASP A  83
 None
 1.27A 5vlmG-5caxA:
undetectable		 5vlmG-5caxA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dfw SINGLE CHAIN FV
FRAGMENT

(Mus musculus) 		PF07686
(V-set) 		4 GLY H 214
TYR H 602
TRP H 798
TYR H 328
 None
 1.17A 5vlmG-5dfwH:
undetectable		 5vlmG-5dfwH:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5esr HALOALKANE
DEHALOGENASE

(Caulobacter
vibrioides) 		PF00561
(Abhydrolase_1) 		4 GLY A  54
TRP A 163
GLN A 168
TYR A  98
 None
CL  A 409 (-4.6A)
None
None
 1.22A 5vlmG-5esrA:
undetectable		 5vlmG-5esrA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffl CD300 ANTIGEN-LIKE
FAMILY MEMBER F

(Mus musculus) 		PF07686
(V-set) 		4 GLY A  12
TRP A  35
GLN A  37
ASP A  84
 None
 1.15A 5vlmG-5fflA:
undetectable		 5vlmG-5fflA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 GLY A  76
TYR A 512
TRP A  69
ASP A  93
 None
PEG  A6002 ( 4.1A)
None
PEG  A6002 (-3.3A)
 1.01A 5vlmG-5fjjA:
undetectable		 5vlmG-5fjjA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq6 SUSC/RAGA FAMILY
TONB-LINKED OUTER
MEMBRANE PROTEIN

(Bacteroides
thetaiotaomicron) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 GLY B 796
GLN B 825
TYR B 802
ASP B 901
 None
 1.20A 5vlmG-5fq6B:
undetectable		 5vlmG-5fq6B:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsb TECTONIN 2

(Laccaria
bicolor) 		no annotation 4 GLY A   5
TRP A 224
TRP A   3
TYR A  33
 None
 1.17A 5vlmG-5fsbA:
undetectable		 5vlmG-5fsbA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyj GP41 ENV ECTODOMAIN

(Human
immunodeficiency
virus 1) 		PF00517
(GP41) 		4 GLY B 594
TRP B 596
ASP B 589
TYR B 586
 None
None
CIT  B1666 (-3.2A)
None
 1.23A 5vlmG-5fyjB:
undetectable		 5vlmG-5fyjB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hax NUCLEOPORIN NUP170

(Chaetomium
thermophilum) 		PF08801
(Nucleoporin_N) 		4 GLY A 474
GLN A 604
TYR A 605
TYR A 110
 None
 1.27A 5vlmG-5haxA:
2.9		 5vlmG-5haxA:
14.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5icq METHYLOCYSTIS PARVUS
OBBP MBNE

(Methylocystis
parvus) 		PF00496
(SBP_bac_5) 		4 GLY A 497
TRP A 513
GLN A 509
TYR A 557
 None
 1.23A 5vlmG-5icqA:
undetectable		 5vlmG-5icqA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ixm LPS-ASSEMBLY PROTEIN
LPTD

(Yersinia pestis) 		PF04453
(OstA_C) 		4 GLY A 366
GLN A 235
TYR A 303
ASP A 299
 None
 0.83A 5vlmG-5ixmA:
undetectable		 5vlmG-5ixmA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5js9 GP41

(Human
immunodeficiency
virus 1) 		PF00517
(GP41) 		4 GLY D 581
TRP D 583
ASP D 576
TYR D 573
 None
 1.29A 5vlmG-5js9D:
undetectable		 5vlmG-5js9D:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ju6 BETA-GLUCOSIDASE

(Rasamsonia
emersonii) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 GLY A  75
TYR A 507
TRP A  68
ASP A  92
 None
None
None
BGC  A 946 (-3.0A)
 1.08A 5vlmG-5ju6A:
undetectable		 5vlmG-5ju6A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldd CCZ1

(Chaetomium
thermophilum) 		PF08217
(DUF1712) 		4 GLY B 121
TRP B 144
GLN B 109
TYR B  23
 None
 1.20A 5vlmG-5lddB:
undetectable		 5vlmG-5lddB:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mal LIPASE

(Streptomyces
rimosus) 		PF13472
(Lipase_GDSL_2) 		4 GLY A  85
GLN A  64
ASP A   9
TYR A  11
 None
 1.19A 5vlmG-5malA:
undetectable		 5vlmG-5malA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mog PHYTOENE
DEHYDROGENASE,
CHLOROPLASTIC/CHROMO
PLASTIC

(Oryza sativa) 		PF01593
(Amino_oxidase) 		4 GLY A 113
TYR A 165
ASP A 531
TYR A 532
 FAD  A 600 (-3.4A)
FAD  A 600 ( 4.5A)
FAD  A 600 (-3.7A)
None
 1.29A 5vlmG-5mogA:
undetectable		 5vlmG-5mogA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mov CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 GLY A 185
TYR A 257
ASP A 210
TYR A 211
 None
 1.14A 5vlmG-5movA:
undetectable		 5vlmG-5movA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5neu INTEGRIN ALPHA-V

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 GLY A 425
TRP A 395
ASP A 430
TYR A  18
 None
 1.25A 5vlmG-5neuA:
undetectable		 5vlmG-5neuA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE

(Zobellia
galactanivorans) 		no annotation 4 GLY A 228
GLN A 181
TYR A 535
TYR A 307
 None
 1.11A 5vlmG-5opqA:
undetectable		 5vlmG-5opqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tuk TETRACYCLINE
DESTRUCTASE TET(51)

(uncultured
bacterium) 		PF01494
(FAD_binding_3) 		4 GLY A  16
TYR A 267
ASP A 289
TYR A 292
 None
FAD  A 402 (-3.7A)
FAD  A 402 (-3.0A)
None
 1.21A 5vlmG-5tukA:
undetectable		 5vlmG-5tukA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tul TETRACYCLINE
DESTRUCTASE TET(55)

(uncultured
bacterium) 		PF01494
(FAD_binding_3) 		4 GLY A  16
TYR A  44
ASP A 289
TYR A 292
 None
None
PO4  A 401 (-4.2A)
None
 1.18A 5vlmG-5tulA:
undetectable		 5vlmG-5tulA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tum TETRACYCLINE
DESTRUCTASE TET(56)

(Legionella
longbeachae) 		PF01494
(FAD_binding_3) 		4 GLY A  16
TYR A 267
ASP A 289
TYR A 292
 None
FAD  A 401 (-3.5A)
FAD  A 401 (-2.4A)
None
 1.19A 5vlmG-5tumA:
undetectable		 5vlmG-5tumA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um8 GLYCOPROTEIN GP41

(Human
immunodeficiency
virus 1) 		PF00517
(GP41) 		4 GLY B 594
TRP B 596
ASP B 589
TYR B 586
 None
 1.25A 5vlmG-5um8B:
undetectable		 5vlmG-5um8B:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5van BETA-KLOTHO

(Homo sapiens) 		no annotation 4 GLY A 249
TRP A 329
TYR A 340
TYR A 194
 None
 1.25A 5vlmG-5vanA:
undetectable		 5vlmG-5vanA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vat PENICILLIN-BINDING
PROTEIN ACTIVATOR
LPOA

(Haemophilus
influenzae) 		PF04348
(LppC) 		4 GLY A 546
GLN A 512
ASP A 488
TYR A 563
 None
 1.23A 5vlmG-5vatA:
2.0		 5vlmG-5vatA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vlg REGULATORY PROTEIN
TETR

([Enterobacter]
lignolyticus) 		no annotation 7 GLY A  88
TRP A 101
GLN A 105
TYR A 118
TRP A 125
ASP A 163
TYR A 166
 MGR  A 300 ( 2.9A)
MGR  A 300 (-3.6A)
MGR  A 300 ( 3.0A)
None
MGR  A 300 (-3.5A)
MGR  A 300 (-3.5A)
MGR  A 300 (-3.0A)
 0.32A 5vlmG-5vlgA:
29.4		 5vlmG-5vlgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w21 KLOTHO

(Homo sapiens) 		no annotation 4 GLY A 247
TRP A 326
TYR A 337
TYR A 192
 None
 1.21A 5vlmG-5w21A:
undetectable		 5vlmG-5w21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wi9 -

(-) 		no annotation 4 GLY A 249
TRP A 329
TYR A 340
TYR A 194
 None
 1.22A 5vlmG-5wi9A:
undetectable		 5vlmG-5wi9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xvu CASEIN KINASE 2,
ALPHA SUBUNIT

(Plasmodium
falciparum) 		PF00069
(Pkinase) 		4 GLY A 189
TYR A 261
ASP A 214
TYR A 215
 None
 1.20A 5vlmG-5xvuA:
undetectable		 5vlmG-5xvuA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6r GENOME POLYPROTEIN

(Pestivirus C) 		no annotation 4 GLY A 404
GLN A 308
TYR A 316
ASP A 409
 None
 1.25A 5vlmG-5y6rA:
undetectable		 5vlmG-5y6rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y6r GENOME POLYPROTEIN

(Pestivirus C) 		no annotation 4 GLY A 406
GLN A 308
TYR A 316
ASP A 409
 None
 1.28A 5vlmG-5y6rA:
undetectable		 5vlmG-5y6rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccb GLYCOPROTEIN 41

(Human
immunodeficiency
virus 1) 		no annotation 4 GLY A 594
TRP A 596
ASP A 589
TYR A 586
 None
 1.21A 5vlmG-6ccbA:
undetectable		 5vlmG-6ccbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eks SIALIDASE

(Vibrio cholerae) 		no annotation 4 GLY A 592
TRP A 620
TYR A 358
ASP A 615
 None
 1.29A 5vlmG-6eksA:
undetectable		 5vlmG-6eksA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f72 MTVAO615

(Thermothelomyces
thermophila) 		no annotation 4 TYR A 231
TRP A 469
ASP A 451
TYR A 342
 FAD  A 601 (-4.7A)
None
None
None
 1.26A 5vlmG-6f72A:
undetectable		 5vlmG-6f72A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f8z ALPHA-1,2-MANNOSIDAS
E, PUTATIVE

(Bacteroides
thetaiotaomicron) 		no annotation 4 GLY A  92
GLN A 395
TRP A 390
ASP A  95
 None
 1.27A 5vlmG-6f8zA:
undetectable		 5vlmG-6f8zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fpe ATPASE YJEE,
PREDICTED TO HAVE
ESSENTIAL ROLE IN
CELL WALL
BIOSYNTHESIS

(Thermotoga
maritima) 		no annotation 4 GLY E 110
TYR E  70
ASP E  80
TYR E  82
 None
None
APC  E 201 ( 4.7A)
None
 1.20A 5vlmG-6fpeE:
undetectable		 5vlmG-6fpeE:
undetectable