SIMILAR PATTERNS OF AMINO ACIDS FOR 5VLM_D_CVID301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bhq | CD11B (Homo sapiens) |
PF00092(VWA) | 4 | GLN 1 298GLY 1 270GLU 1 283ASP 1 140 | NoneNoneNone CD 1 901 ( 3.9A) | 1.06A | 5vlmD-1bhq1:undetectable | 5vlmD-1bhq1:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cs1 | PROTEIN(CYSTATHIONINEGAMMA-SYNTHASE) (Escherichiacoli) |
PF01053(Cys_Met_Meta_PP) | 4 | GLY A 125GLU A 127ILE A 159GLN A 182 | None | 0.98A | 5vlmD-1cs1A:0.0 | 5vlmD-1cs1A:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ekb | ENTEROPEPTIDASE (Bos taurus) |
PF00089(Trypsin) | 4 | GLN B 156GLY B 18ILE B 145GLN B 219 | None | 1.00A | 5vlmD-1ekbB:undetectable | 5vlmD-1ekbB:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ev1 | ECHOVIRUS 1ECHOVIRUS 1 (Enterovirus B;Enterovirus B) |
PF00073(Rhv)PF00073(Rhv) | 4 | GLY 2 133ILE 2 146TRP 2 79ASP 1 197 | None | 0.92A | 5vlmD-1ev12:undetectable | 5vlmD-1ev12:20.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f8w | NADH PEROXIDASE (Enterococcusfaecalis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | GLY A 322GLU A 267GLN A 385ASP A 291 | None | 0.97A | 5vlmD-1f8wA:0.0 | 5vlmD-1f8wA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i54 | CYTOCHROME C (Thunnus thynnus) |
PF00034(Cytochrom_C) | 4 | GLN A 92GLY A 89ILE A 85GLN A 12 | None | 1.07A | 5vlmD-1i54A:undetectable | 5vlmD-1i54A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1keh | PRECURSOR OFCEPHALOSPORINACYLASE (Brevundimonasdiminuta) |
PF01804(Penicil_amidase) | 4 | GLN A 46GLY A 43ILE A 30TRP A 22 | None | 1.05A | 5vlmD-1kehA:0.0 | 5vlmD-1kehA:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyi | ATP-DEPENDENT HSLPROTEASE ATP-BINDINGSUBUNIT HSLU (Haemophilusinfluenzae) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 20GLY A 62ILE A 344GLN A 355 | NoneATP A 450 (-3.5A)ATP A 450 (-4.0A)None | 1.01A | 5vlmD-1kyiA:0.0 | 5vlmD-1kyiA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8k | T-CELLPROTEIN-TYROSINEPHOSPHATASE (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | GLY A 239GLU A 78ILE A 242ASP A 241 | None | 0.96A | 5vlmD-1l8kA:0.0 | 5vlmD-1l8kA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lm5 | SUBDOMAIN OFDESMOPLAKINCARBOXY-TERMINALDOMAIN (DPCT) (Homo sapiens) |
PF00681(Plectin) | 4 | GLN A2730GLY A2735ILE A2756GLN A2762 | None | 0.91A | 5vlmD-1lm5A:0.0 | 5vlmD-1lm5A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mu2 | HIV-2 RTHIV-2 RT (Humanimmunodeficiencyvirus 2;Humanimmunodeficiencyvirus 2) |
PF00075(RNase_H)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb)PF00078(RVT_1)PF06815(RVT_connect)PF06817(RVT_thumb) | 4 | GLY A 383GLU B 29ILE A 385GLN A 372 | None | 0.91A | 5vlmD-1mu2A:0.2 | 5vlmD-1mu2A:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ofh | ATP-DEPENDENT HSLPROTEASE ATP-BINDINGSUBUNIT HSLU (Haemophilusinfluenzae) |
PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 20GLY A 62ILE A 344GLN A 355 | NoneADP A 450 (-3.3A)ADP A 450 ( 4.0A)None | 0.94A | 5vlmD-1ofhA:undetectable | 5vlmD-1ofhA:25.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rm8 | MATRIXMETALLOPROTEINASE-16 (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | GLN A 287GLY A 285GLN A 269ASP A 259 | None | 1.07A | 5vlmD-1rm8A:undetectable | 5vlmD-1rm8A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t8w | AMP NUCLEOSIDASE (Escherichiacoli) |
PF01048(PNP_UDP_1)PF10423(AMNp_N) | 4 | GLN A 271GLY A 272ILE A 460GLN A 454 | None | 0.88A | 5vlmD-1t8wA:undetectable | 5vlmD-1t8wA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua7 | ALPHA-AMYLASE (Bacillussubtilis) |
PF00128(Alpha-amylase) | 4 | GLN A 63GLY A 48GLN A 321ASP A 52 | GLC A 503 ( 3.9A)NoneNoneNone | 1.02A | 5vlmD-1ua7A:undetectable | 5vlmD-1ua7A:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1um8 | ATP-DEPENDENT CLPPROTEASE ATP-BINDINGSUBUNIT CLPX (Helicobacterpylori) |
PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 96GLY A 154ILE A 351GLN A 362 | NoneADP A 487 (-2.7A)ADP A 487 (-3.9A)None | 0.98A | 5vlmD-1um8A:undetectable | 5vlmD-1um8A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1q | TRYPTOPHAN SYNTHASEBETA CHAIN (Thermusthermophilus) |
PF00291(PALP) | 4 | GLN A 136GLY A 106GLU A 100ILE A 110 | None | 0.99A | 5vlmD-1x1qA:undetectable | 5vlmD-1x1qA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xw8 | UPF0271 PROTEIN YBGL (Escherichiacoli) |
PF03746(LamB_YcsF) | 4 | GLN A 85GLY A 31ILE A 28GLN A 96 | None | 1.02A | 5vlmD-1xw8A:undetectable | 5vlmD-1xw8A:25.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zj9 | PROBABLEFERREDOXIN-DEPENDENTNITRITE REDUCTASENIRA (Mycobacteriumtuberculosis) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | GLY A 479GLU A 491ILE A 460GLN A 379 | NoneNoneNoneSRM A 569 (-3.9A) | 1.02A | 5vlmD-1zj9A:undetectable | 5vlmD-1zj9A:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bjr | MFP2B (Ascaris suum) |
PF12150(MFP2b) | 4 | GLY A 326GLU A 343ILE A 312GLN A 31 | None | 1.07A | 5vlmD-2bjrA:undetectable | 5vlmD-2bjrA:17.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ec5 | DERMONECROTIC TOXIN (Pasteurellamultocida) |
PF11647(MLD) | 4 | GLY A 689GLU A 639ILE A 683GLN A 719 | None | 1.05A | 5vlmD-2ec5A:2.2 | 5vlmD-2ec5A:13.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i0m | PHOSPHATE TRANSPORTSYSTEM PROTEIN PHOU (Streptococcuspneumoniae) |
PF01895(PhoU) | 4 | GLN A 182GLY A 180ILE A 187GLN A 118 | None | 0.91A | 5vlmD-2i0mA:1.9 | 5vlmD-2i0mA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lgh | UNCHARACTERIZEDPROTEIN (Aeromonashydrophila) |
PF08327(AHSA1) | 4 | GLY A 68TRP A 121GLN A 117ASP A 85 | None | 1.04A | 5vlmD-2lghA:undetectable | 5vlmD-2lghA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vj5 | PROTEIN MXIC (Shigellaflexneri) |
PF07201(HrpJ) | 4 | GLN A 121ILE A 145GLN A 138ASP A 104 | None | 1.05A | 5vlmD-2vj5A:3.6 | 5vlmD-2vj5A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 4 | GLN A 560GLY A 498GLU A 584ILE A 495 | None | 1.02A | 5vlmD-2vz9A:undetectable | 5vlmD-2vz9A:5.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3p | BENZOYL-COA-DIHYDRODIOL LYASE (Paraburkholderiaxenovorans) |
PF00378(ECH_1) | 4 | GLY A 93ILE A 38TRP A 23ASP A 56 | None | 0.89A | 5vlmD-2w3pA:undetectable | 5vlmD-2w3pA:15.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3l | ORN/LYS/ARGDECARBOXYLASE FAMILYPROTEIN (Staphylococcusaureus) |
PF01276(OKR_DC_1)PF03711(OKR_DC_1_C) | 4 | GLN A 309GLY A 305ILE A 298TRP A 311 | None | 1.03A | 5vlmD-2x3lA:undetectable | 5vlmD-2x3lA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yk0 | ERYTHROCYTE MEMBRANEPROTEIN 1 (Plasmodiumfalciparum) |
PF03011(PFEMP)PF05424(Duffy_binding)PF15447(NTS) | 4 | GLY A 627ILE A 644TRP A 579ASP A 694 | None | 1.03A | 5vlmD-2yk0A:2.8 | 5vlmD-2yk0A:13.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1q | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | GLN A 371GLY A 374ILE A 296GLN A 288 | None | 1.04A | 5vlmD-2z1qA:1.0 | 5vlmD-2z1qA:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e82 | PUTATIVEOXIDOREDUCTASE (Klebsiellapneumoniae) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | GLN A 146GLY A 143GLN A 307ASP A 264 | None | 0.99A | 5vlmD-3e82A:undetectable | 5vlmD-3e82A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3onp | TRNA/RRNAMETHYLTRANSFERASE(SPOU) (Rhodobactersphaeroides) |
PF00588(SpoU_methylase) | 4 | GLY A 108ILE A 3TRP A 158GLN A 161 | None | 1.09A | 5vlmD-3onpA:undetectable | 5vlmD-3onpA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozv | FLAVOHEMOGLOBIN (Cupriavidusnecator) |
no annotation | 4 | GLN B 52GLY B 51ILE B 25GLN B 30 | NoneNoneECN B 411 (-4.5A)None | 1.00A | 5vlmD-3ozvB:2.1 | 5vlmD-3ozvB:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qqy | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEPROTEIN FUSION (Ophiostomanovo-ulmi) |
PF00961(LAGLIDADG_1) | 4 | GLN A 46GLY A 44TRP A 64ASP A 86 | None | 1.06A | 5vlmD-3qqyA:undetectable | 5vlmD-3qqyA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7k | PROBABLE ACYL COADEHYDROGENASE (Mycobacteroidesabscessus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | GLY A 181GLU A 56ILE A 141ASP A 185 | None | 1.00A | 5vlmD-3r7kA:2.5 | 5vlmD-3r7kA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sfz | APOPTOTIC PEPTIDASEACTIVATING FACTOR 1 (Mus musculus) |
PF00400(WD40)PF00931(NB-ARC)PF12894(ANAPC4_WD40) | 4 | GLN A 545GLU A 525ILE A 510GLN A 583 | None | 0.98A | 5vlmD-3sfzA:undetectable | 5vlmD-3sfzA:11.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v9f | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSEREGULATOR, HYBRID(ONE-COMPONENTSYSTEM) (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 4 | GLY A 709GLU A 768ILE A 685GLN A 727 | None | 0.94A | 5vlmD-3v9fA:undetectable | 5vlmD-3v9fA:12.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3va7 | KLLA0E08119P (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | GLN A 833GLY A 846GLU A 881ILE A 950 | None | 1.04A | 5vlmD-3va7A:undetectable | 5vlmD-3va7A:9.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vax | PUTATIVEUNCHARACTERIZEDPROTEIN DNDA (Streptomyceslividans) |
PF00266(Aminotran_5) | 4 | GLN A 178GLY A 179ILE A 155ASP A 186 | None | 0.83A | 5vlmD-3vaxA:undetectable | 5vlmD-3vaxA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zcw | KINESIN-LIKE PROTEINKIF11 (Homo sapiens) |
PF00225(Kinesin) | 4 | GLY A 217ILE A 136GLN A 78TRP A 127 | 4A2 A1367 (-3.3A)4A2 A1367 (-3.4A)NoneNone | 0.89A | 5vlmD-3zcwA:undetectable | 5vlmD-3zcwA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ak9 | CPFTSY (Physcomitrellapatens) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | GLY A 361GLU A 364GLN A 319ASP A 309 | None | 1.09A | 5vlmD-4ak9A:2.8 | 5vlmD-4ak9A:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bpc | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE S (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | GLN A1934GLY A1853TRP A1844ASP A1843 | None | 1.00A | 5vlmD-4bpcA:undetectable | 5vlmD-4bpcA:15.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ciu | CHAPERONE PROTEINCLPB (Escherichiacoli) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 454GLU A 459ILE A 419GLN A 426 | None | 1.06A | 5vlmD-4ciuA:2.3 | 5vlmD-4ciuA:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fwg | TTC1975 PEPTIDASE (Meiothermustaiwanensis) |
PF05362(Lon_C)PF13654(AAA_32) | 4 | GLN A 357GLY A 45GLU A 40ILE A 382 | None | 1.03A | 5vlmD-4fwgA:undetectable | 5vlmD-4fwgA:14.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ghk | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Burkholderiathailandensis) |
PF00171(Aldedh) | 4 | GLN A 175GLY A 165GLU A 170ASP A 43 | None | 1.07A | 5vlmD-4ghkA:undetectable | 5vlmD-4ghkA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hnl | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME (Enterococcusgallinarum) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | GLN A 283GLY A 83TRP A 265GLN A 266 | None CL A 403 ( 3.9A)NoneNone | 1.00A | 5vlmD-4hnlA:undetectable | 5vlmD-4hnlA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irt | UNCHARACTERIZEDPROTEIN (Bacteroidesovatus) |
PF15892(BNR_4) | 4 | GLU A 191ILE A 188TRP A 198GLN A 199 | NoneEDO A 510 (-3.9A)NoneNone | 1.08A | 5vlmD-4irtA:undetectable | 5vlmD-4irtA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3c | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA ([Haemophilus]ducreyi) |
PF01103(Bac_surface_Ag)PF07244(POTRA) | 4 | GLY A 661ILE A 667GLN A 684ASP A 780 | None | 1.07A | 5vlmD-4k3cA:undetectable | 5vlmD-4k3cA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mtn | TRANSCRIPTIONTERMINATION FACTORNUSA (Planctopiruslimnophila) |
PF00575(S1)PF08529(NusA_N)PF13184(KH_5)PF14520(HHH_5) | 4 | GLN A 30GLY A 27GLU A 22ILE A 50 | None | 1.08A | 5vlmD-4mtnA:undetectable | 5vlmD-4mtnA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mvt | E3 SUMO-PROTEINLIGASE PIAS3 (Homo sapiens) |
PF02891(zf-MIZ)PF14324(PINIT) | 4 | GLY A 139GLU A 136ILE A 188GLN A 170 | UNX A 506 ( 3.9A)NoneNoneNone | 0.87A | 5vlmD-4mvtA:undetectable | 5vlmD-4mvtA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nf8 | GLUTAMATE RECEPTORIONOTROPIC, NMDA 1 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | GLN A 178GLY A 93GLU A 112TRP A 223 | None | 1.05A | 5vlmD-4nf8A:undetectable | 5vlmD-4nf8A:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o2l | GTP-BINDING PROTEINRHEB (Mus musculus) |
PF00071(Ras) | 4 | GLN A 52GLY A 51ILE A 47GLN A 154 | None | 1.06A | 5vlmD-4o2lA:undetectable | 5vlmD-4o2lA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oko | RAPID ENCYSTMENTPHENOTYPE PROTEIN 34KDA (Francisellatularensis) |
PF00246(Peptidase_M14) | 4 | GLY A 201GLU A 272ILE A 198ASP A 276 | NoneACT A 402 (-3.4A)NoneNone | 0.99A | 5vlmD-4okoA:undetectable | 5vlmD-4okoA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4otk | MYCOBACTERIAL ENZYMERV2971 (Mycobacteriumtuberculosis) |
PF00248(Aldo_ket_red) | 4 | GLY A 47GLU A 45ILE A 244GLN A 221 | None | 0.85A | 5vlmD-4otkA:undetectable | 5vlmD-4otkA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p0f | SERINE PROTEASEINHIBITOR 4, ISOFORMB (Drosophilamelanogaster) |
PF00079(Serpin) | 4 | GLN A 41GLY A 64GLU A 8ILE A 73 | None | 0.94A | 5vlmD-4p0fA:undetectable | 5vlmD-4p0fA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4psp | ALPHA-FUCOSIDASEGH29 (Fusariumgraminearum) |
PF01120(Alpha_L_fucos)PF16757(Fucosidase_C) | 4 | GLY A 236GLU A 234GLN A 59TRP A 182 | None | 1.05A | 5vlmD-4pspA:undetectable | 5vlmD-4pspA:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rbn | SUCROSESYNTHASE:GLYCOSYLTRANSFERASES GROUP 1 (Nitrosomonaseuropaea) |
PF00534(Glycos_transf_1)PF00862(Sucrose_synth) | 4 | GLN A 142GLU A 689ILE A 473GLN A 487 | None | 1.05A | 5vlmD-4rbnA:undetectable | 5vlmD-4rbnA:12.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rh7 | GREEN FLUORESCENTPROTEIN/CYTOPLASMICDYNEIN 2 HEAVY CHAIN1 (Homo sapiens;syntheticconstruct) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | GLY A1982GLU A2095ILE A2424GLN A2285 | ATP A4403 (-3.3A) MG A4404 ( 2.9A)NoneNone | 1.03A | 5vlmD-4rh7A:undetectable | 5vlmD-4rh7A:4.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLN A 247GLY A 422ILE A 398GLN A 487 | None | 0.93A | 5vlmD-4rjkA:undetectable | 5vlmD-4rjkA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rlc | OUTER MEMBRANE PORINF (Pseudomonasaeruginosa) |
PF05736(OprF) | 4 | GLY A 34GLU A 9ILE A 74ASP A 72 | C8E A 207 ( 4.3A)NoneNoneNone | 1.05A | 5vlmD-4rlcA:undetectable | 5vlmD-4rlcA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjl | INACTIVE DIPEPTIDYLPEPTIDASE 10 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 4 | GLN A 451GLY A 449GLU A 494ILE A 426 | None | 0.92A | 5vlmD-4wjlA:undetectable | 5vlmD-4wjlA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xb6 | ALPHA-D-RIBOSE1-METHYLPHOSPHONATE5-TRIPHOSPHATESYNTHASE SUBUNITPHNIALPHA-D-RIBOSE1-METHYLPHOSPHONATE5-PHOSPHATE C-PLYASE (Escherichiacoli;Escherichiacoli) |
PF05861(PhnI)PF06007(PhnJ) | 4 | GLY D 38GLU D 41ILE C 178ASP C 177 | None | 1.04A | 5vlmD-4xb6D:undetectable | 5vlmD-4xb6D:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yhx | RIBOSOMAL PROTEIN3/HOMINGENDONUCLEASE-LIKEFUSION PROTEIN (Grosmanniapenicillata) |
PF00961(LAGLIDADG_1) | 4 | GLN A 43GLY A 41TRP A 61ASP A 83 | None | 1.01A | 5vlmD-4yhxA:undetectable | 5vlmD-4yhxA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yk8 | MEIOTICALLYUP-REGULATED GENE 66PROTEIN (Schizosaccharomycespombe) |
PF07855(ATG101) | 4 | GLN A 135ILE A 7TRP A 106GLN A 105 | None | 1.08A | 5vlmD-4yk8A:undetectable | 5vlmD-4yk8A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylj | DUAL SPECIFICITYTYROSINE-PHOSPHORYLATION-REGULATEDKINASE 1A (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 313GLY A 315ILE A 318GLN A 320 | None | 0.93A | 5vlmD-4yljA:undetectable | 5vlmD-4yljA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0t | OXIDOREDUCTASE,SHORT-CHAINDEHYDROGENASE/REDUCTASE FAMILY (Brucella ovis) |
PF00106(adh_short) | 4 | GLN A 197GLY A 188ILE A 19GLN A 211 | NoneNone BR A 304 (-4.5A)None | 0.75A | 5vlmD-4z0tA:undetectable | 5vlmD-4z0tA:24.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zox | RIBOSOME ASSEMBLYPROTEIN SQT1 (Saccharomycescerevisiae) |
no annotation | 4 | GLN A 239GLY A 238GLN A 201TRP A 233 | None | 1.04A | 5vlmD-4zoxA:undetectable | 5vlmD-4zoxA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zuz | SIDC (Legionellapneumophila) |
no annotation | 4 | GLY A 627GLU A 713ILE A 634GLN A 135 | None | 1.06A | 5vlmD-4zuzA:undetectable | 5vlmD-4zuzA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a31 | ANAPHASE-PROMOTINGCOMPLEX SUBUNIT 5 (Homo sapiens) |
PF12862(ANAPC5) | 4 | GLY O 661GLU O 696ILE O 648GLN O 617 | None | 0.88A | 5vlmD-5a31O:2.2 | 5vlmD-5a31O:13.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c2v | HYDRAZINE SYNTHASEALPHA SUBUNIT (CandidatusKueneniastuttgartiensis) |
no annotation | 4 | GLY A 383TRP A 335GLN A 74ASP A 71 | None | 1.02A | 5vlmD-5c2vA:undetectable | 5vlmD-5c2vA:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d68 | KREV INTERACTIONTRAPPED PROTEIN 1 (Homo sapiens) |
PF00373(FERM_M)PF13857(Ank_5) | 4 | GLN A 689GLY A 691ILE A 709GLN A 643 | None | 0.95A | 5vlmD-5d68A:2.7 | 5vlmD-5d68A:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7j | ATP-DEPENDENT RNAHELICASE DDX3X (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | GLY A 302GLU A 481ILE A 306ASP A 329 | None | 1.04A | 5vlmD-5e7jA:undetectable | 5vlmD-5e7jA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fgn | LIPOOLIGOSACCHARIDEPHOSPHOETHANOLAMINETRANSFERASE A (Neisseriameningitidis) |
PF00884(Sulfatase)PF08019(DUF1705) | 4 | GLN A 223GLY A 315GLU A 317GLN A 216 | None | 1.06A | 5vlmD-5fgnA:undetectable | 5vlmD-5fgnA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fjj | BETA-GLUCOSIDASE (Aspergillusoryzae) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | GLY A 602GLU A 606ILE A 525TRP A 601 | None | 1.05A | 5vlmD-5fjjA:undetectable | 5vlmD-5fjjA:13.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fql | IDURONATE-2-SULFATASE (Homo sapiens) |
PF00884(Sulfatase) | 4 | GLN A 465GLY A 489ILE A 485GLN A 474 | None | 1.03A | 5vlmD-5fqlA:undetectable | 5vlmD-5fqlA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 4 | GLN A 227GLY A 228ILE A 271GLN A 199 | None | 0.97A | 5vlmD-5g5nA:undetectable | 5vlmD-5g5nA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | GLN A 833GLY A 846GLU A 881ILE A 950 | None | 1.04A | 5vlmD-5i8iA:undetectable | 5vlmD-5i8iA:6.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikj | CRYPTIC LOCIREGULATOR 2 (Schizosaccharomycespombe) |
PF10383(Clr2)PF16761(Clr2_transil) | 4 | GLY A 285GLU A 514ILE A 319TRP A 301 | None | 1.06A | 5vlmD-5ikjA:undetectable | 5vlmD-5ikjA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k10 | ISOCITRATEDEHYDROGENASE [NADP]CYTOPLASMIC (Homo sapiens) |
PF00180(Iso_dh) | 4 | GLN A 14GLY A 15ILE A 21GLN A 320 | None | 1.07A | 5vlmD-5k10A:undetectable | 5vlmD-5k10A:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kel | EBOLA SURFACEGLYCOPROTEIN, GP1C13C6 VARIABLE FABDOMAIN HEAVY CHAIN (Zaireebolavirus;Homo sapiens) |
PF01611(Filo_glycop)PF07686(V-set) | 4 | GLN A 221GLY A 143GLU A 112TRP C 53 | None | 0.96A | 5vlmD-5kelA:undetectable | 5vlmD-5kelA:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2r | FUMARATE HYDRATASE (Leishmaniamajor) |
PF05681(Fumerase)PF05683(Fumerase_C) | 4 | GLY A 483GLU A 440ILE A 395GLN A 400 | None | 1.00A | 5vlmD-5l2rA:undetectable | 5vlmD-5l2rA:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l3r | CELL DIVISIONPROTEIN FTSYHOMOLOG,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00448(SRP54)PF02881(SRP54_N) | 4 | GLY B 344GLU B 347GLN B 302ASP B 292 | GCP B 401 (-3.5A)GCP B 401 (-3.5A)NoneNone | 1.05A | 5vlmD-5l3rB:3.0 | 5vlmD-5l3rB:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz9 | - (-) |
no annotation | 4 | GLN A 231GLY A 232GLU A 166ASP A 236 | None | 1.04A | 5vlmD-5mz9A:undetectable | 5vlmD-5mz9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ohs | - (-) |
no annotation | 4 | GLY A 440ILE A 451TRP A 452GLN A 456 | NoneNoneNSQ A 709 (-4.9A)None | 0.97A | 5vlmD-5ohsA:undetectable | 5vlmD-5ohsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti8 | AMINOTRANSFERASE (Pseudomonas sp.M1) |
PF00202(Aminotran_3) | 4 | GLN A 359GLY A 381ILE A 230GLN A 187 | None | 1.06A | 5vlmD-5ti8A:undetectable | 5vlmD-5ti8A:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txv | ATP-DEPENDENTPROTEASE ATPASESUBUNIT HSLU (Escherichiacoli) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 20GLY A 62ILE A 343GLN A 354 | NoneADP A 501 (-3.2A)ADP A 501 ( 4.5A)None | 0.89A | 5vlmD-5txvA:undetectable | 5vlmD-5txvA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1b | EGL NINE HOMOLOG 2 (Homo sapiens) |
PF13640(2OG-FeII_Oxy_3) | 4 | GLN A 393GLY A 392TRP A 373ASP A 304 | NoneSO4 A 501 ( 3.8A)NoneNone | 1.05A | 5vlmD-5v1bA:undetectable | 5vlmD-5v1bA:24.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v1w | GLYCOSIDE HYDROLASE (Bacillushalodurans) |
PF03639(Glyco_hydro_81) | 4 | GLY A 390GLU A 546GLN A 58TRP A 426 | NoneEDO A 819 (-3.2A)NoneNone | 0.96A | 5vlmD-5v1wA:1.6 | 5vlmD-5v1wA:15.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgz | 26S PROTEASOMEREGULATORY SUBUNIT 726S PROTEASOMEREGULATORY SUBUNIT 4 (Homo sapiens;Homo sapiens) |
no annotationno annotation | 4 | GLY B 161ILE B 135GLN A 85ASP A 79 | None | 1.06A | 5vlmD-5vgzB:undetectable | 5vlmD-5vgzB:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vlg | REGULATORY PROTEINTETR ([Enterobacter]lignolyticus) |
no annotation | 6 | GLN A 71GLU A 90ILE A 98TRP A 101GLN A 105ASP A 163 | MGR A 300 ( 4.1A)MGR A 300 (-4.1A)MGR A 300 (-3.1A)MGR A 300 (-3.6A)MGR A 300 ( 3.0A)MGR A 300 (-3.5A) | 1.24A | 5vlmD-5vlgA:29.7 | 5vlmD-5vlgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vlg | REGULATORY PROTEINTETR ([Enterobacter]lignolyticus) |
no annotation | 7 | GLN A 71GLY A 88ILE A 98TRP A 101GLN A 105TRP A 125ASP A 163 | MGR A 300 ( 4.1A)MGR A 300 ( 2.9A)MGR A 300 (-3.1A)MGR A 300 (-3.6A)MGR A 300 ( 3.0A)MGR A 300 (-3.5A)MGR A 300 (-3.5A) | 0.66A | 5vlmD-5vlgA:29.7 | 5vlmD-5vlgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vmb | SERINEHYDROXYMETHYLTRANSFERASE (Acinetobacterbaumannii) |
PF00464(SHMT) | 5 | GLN A 295GLY A 312ILE A 302GLN A 325ASP A 307 | None | 1.09A | 5vlmD-5vmbA:undetectable | 5vlmD-5vmbA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wf2 | UNCHARACTERIZEDPROTEIN (Equus caballus) |
no annotation | 4 | GLN A 379GLY A 372GLU A 410ILE A 368 | None | 0.99A | 5vlmD-5wf2A:3.4 | 5vlmD-5wf2A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x8t | PROTEIN L27 (Spinaciaoleracea) |
PF01016(Ribosomal_L27) | 4 | GLN X 85GLY X 83ILE X 93GLN X 96 | A A 932 ( 2.6A) G A 866 ( 3.3A)NoneNone | 0.99A | 5vlmD-5x8tX:undetectable | 5vlmD-5x8tX:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjj | MULTI DRUG EFFLUXTRANSPORTER (Camelina sativa) |
PF01554(MatE) | 4 | GLN A 459GLY A 397ILE A 401GLN A 443 | OLC A 501 ( 4.5A)NoneNoneNone | 1.05A | 5vlmD-5xjjA:undetectable | 5vlmD-5xjjA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xvs | GDP/UDP-N,N'-DIACETYLBACILLOSAMINE2-EPIMERASE(HYDROLYZING) (Acinetobacterbaumannii) |
no annotation | 4 | GLY A 102GLU A 106ILE A 138ASP A 135 | None | 0.99A | 5vlmD-5xvsA:undetectable | 5vlmD-5xvsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bhu | MULTIDRUGRESISTANCE-ASSOCIATED PROTEIN 1 (Bos taurus) |
no annotation | 4 | GLN A1008GLY A1006ILE A1003TRP A 998 | None | 0.91A | 5vlmD-6bhuA:undetectable | 5vlmD-6bhuA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bog | RNAPOLYMERASE-ASSOCIATED PROTEIN RAPA (Escherichiacoli) |
no annotation | 4 | GLY A 954GLU A 896ILE A 903ASP A 951 | None | 0.79A | 5vlmD-6bogA:3.0 | 5vlmD-6bogA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bq1 | PROTEIN FAM126A (Homo sapiens) |
no annotation | 4 | GLN C 218GLY C 214ILE C 226TRP C 84 | None | 1.06A | 5vlmD-6bq1C:1.9 | 5vlmD-6bq1C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g2j | NADH-UBIQUINONEOXIDOREDUCTASE CHAIN5NADH-UBIQUINONEOXIDOREDUCTASE CHAIN4 (Mus musculus;Mus musculus) |
no annotationno annotation | 4 | GLY M 397GLU M 378ILE L 183ASP L 179 | None | 1.05A | 5vlmD-6g2jM:undetectable | 5vlmD-6g2jM:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gqd | GALACTOSE-1-PHOSPHATEURIDYLYLTRANSFERASE (Homo sapiens) |
no annotation | 4 | GLU A 40ILE A 198TRP A 167TRP A 316 | None | 1.07A | 5vlmD-6gqdA:undetectable | 5vlmD-6gqdA:undetectable |