SIMILAR PATTERNS OF AMINO ACIDS FOR 5VLM_C_CVIC301_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eom | ENDO-BETA-N-ACETYLGLUCOSAMINIDASE F3 (Elizabethkingiameningoseptica) |
PF00704(Glyco_hydro_18) | 4 | GLN A 182ILE A 80GLN A 71TYR A 274 | None | 0.97A | 5vlmC-1eomA:undetectable | 5vlmC-1eomA:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fps | FARNESYL DIPHOSPHATESYNTHASE (Gallus gallus) |
PF00348(polyprenyl_synt) | 4 | GLN A 254GLY A 250ILE A 362GLN A 340 | None | 1.16A | 5vlmC-1fpsA:1.8 | 5vlmC-1fpsA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i84 | SMOOTH MUSCLE MYOSINHEAVY CHAIN (Gallus gallus) |
PF00063(Myosin_head)PF00612(IQ)PF01576(Myosin_tail_1)PF02736(Myosin_N) | 4 | GLN S 361GLY S 363GLN S 418ASP S 424 | None | 1.05A | 5vlmC-1i84S:0.7 | 5vlmC-1i84S:10.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iqp | RFCS (Pyrococcusfuriosus) |
PF00004(AAA)PF08542(Rep_fac_C) | 4 | GLN A 195GLY A 193ILE A 200GLN A 265 | None | 1.11A | 5vlmC-1iqpA:3.0 | 5vlmC-1iqpA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jtd | BETA-LACTAMASEINHIBITOR PROTEIN II (Streptomycesexfoliatus) |
PF13540(RCC1_2) | 4 | GLN B 94GLY B 128GLN B 172ASP B 131 | None | 1.09A | 5vlmC-1jtdB:undetectable | 5vlmC-1jtdB:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k38 | BETA-LACTAMASE OXA-2 (Salmonellaenterica) |
PF00905(Transpeptidase) | 4 | ILE A 71GLN A 185TRP A 218TYR A 141 | KCX A 70 ( 4.3A)NoneNoneNone | 1.10A | 5vlmC-1k38A:undetectable | 5vlmC-1k38A:24.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lm5 | SUBDOMAIN OFDESMOPLAKINCARBOXY-TERMINALDOMAIN (DPCT) (Homo sapiens) |
PF00681(Plectin) | 4 | GLN A2730GLY A2735ILE A2756GLN A2762 | None | 0.90A | 5vlmC-1lm5A:undetectable | 5vlmC-1lm5A:22.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lsh | LIPOVITELLIN (LV-1N,LV-1C) (Ichthyomyzonunicuspis) |
PF01347(Vitellogenin_N)PF09172(DUF1943) | 4 | GLY A 484ILE A 489GLN A 530ASP A 525 | None | 1.17A | 5vlmC-1lshA:1.6 | 5vlmC-1lshA:11.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwy | PEPTIDOGLYCANHYDROLASE (Staphylococcusaureus) |
PF01551(Peptidase_M23) | 4 | GLY A 285GLN A 295ASP A 119TYR A 239 | None | 1.12A | 5vlmC-1qwyA:undetectable | 5vlmC-1qwyA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rm8 | MATRIXMETALLOPROTEINASE-16 (Homo sapiens) |
PF00413(Peptidase_M10) | 4 | GLN A 287GLY A 285GLN A 269ASP A 259 | None | 1.07A | 5vlmC-1rm8A:0.3 | 5vlmC-1rm8A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rpu | 19 KDA PROTEIN (CarnationItalianringspot virus) |
PF03220(Tombus_P19) | 4 | GLY A 88ILE A 138GLN A 131TYR A 112 | None | 1.08A | 5vlmC-1rpuA:undetectable | 5vlmC-1rpuA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t8w | AMP NUCLEOSIDASE (Escherichiacoli) |
PF01048(PNP_UDP_1)PF10423(AMNp_N) | 4 | GLN A 271GLY A 272ILE A 460GLN A 454 | None | 1.00A | 5vlmC-1t8wA:0.0 | 5vlmC-1t8wA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tis | THYMIDYLATE SYNTHASE (Escherichiavirus T4) |
PF00303(Thymidylat_synt) | 4 | GLN A 175GLY A 183ILE A 188GLN A 5 | None | 1.11A | 5vlmC-1tisA:0.0 | 5vlmC-1tisA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tnu | GERANYLGERANYLTRANSFERASE TYPE IBETA SUBUNIT (Rattusnorvegicus) |
PF00432(Prenyltrans) | 4 | GLN B 155GLY B 190ILE B 181GLN B 80 | None | 1.07A | 5vlmC-1tnuB:0.8 | 5vlmC-1tnuB:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ua7 | ALPHA-AMYLASE (Bacillussubtilis) |
PF00128(Alpha-amylase) | 4 | GLN A 63GLY A 48GLN A 321ASP A 52 | GLC A 503 ( 3.9A)NoneNoneNone | 0.95A | 5vlmC-1ua7A:undetectable | 5vlmC-1ua7A:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1um8 | ATP-DEPENDENT CLPPROTEASE ATP-BINDINGSUBUNIT CLPX (Helicobacterpylori) |
PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 96GLY A 154ILE A 351GLN A 362 | NoneADP A 487 (-2.7A)ADP A 487 (-3.9A)None | 1.07A | 5vlmC-1um8A:undetectable | 5vlmC-1um8A:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ups | GLCNAC-ALPHA-1,4-GAL-RELEASINGENDO-BETA-GALACTOSIDASE (Clostridiumperfringens) |
PF00722(Glyco_hydro_16) | 4 | GLN A 146GLY A 144ILE A 78ASP A 255 | None | 1.16A | 5vlmC-1upsA:undetectable | 5vlmC-1upsA:16.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vbj | PROSTAGLANDIN FSYNTHASE (Trypanosomabrucei) |
PF00248(Aldo_ket_red) | 4 | GLN A 83GLY A 113GLN A 170TRP A 111 | NoneNoneNoneCIT A4001 (-4.4A) | 1.07A | 5vlmC-1vbjA:undetectable | 5vlmC-1vbjA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfu | CALMODULIN-SENSITIVEADENYLATE CYCLASE (Bacillusanthracis) |
PF03497(Anthrax_toxA)PF07737(ATLF) | 4 | GLY A 358ILE A 474GLN A 368TYR A 363 | None | 1.12A | 5vlmC-1xfuA:undetectable | 5vlmC-1xfuA:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bb0 | IMIDAZOLONEPROPIONASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 4 | GLN A 162GLY A 183ILE A 112GLN A 192 | NoneNoneACT A1501 (-4.5A)None | 1.12A | 5vlmC-2bb0A:undetectable | 5vlmC-2bb0A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d1g | ACID PHOSPHATASE (Francisellatularensis) |
PF04185(Phosphoesterase) | 4 | GLN A 100GLY A 351GLN A 254TYR A 385 | None | 1.04A | 5vlmC-2d1gA:undetectable | 5vlmC-2d1gA:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dm0 | TYROSINE-PROTEINKINASE TXK (Homo sapiens) |
PF00017(SH2) | 4 | GLN A 34GLY A 118ILE A 42GLN A 100 | None | 1.16A | 5vlmC-2dm0A:undetectable | 5vlmC-2dm0A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fui | BROMODOMAIN PHDFINGER TRANSCRIPTIONFACTOR (Homo sapiens) |
PF00628(PHD) | 4 | GLN A 42ILE A 24GLN A 55TYR A 17 | None | 1.17A | 5vlmC-2fuiA:undetectable | 5vlmC-2fuiA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i00 | ACETYLTRANSFERASE,GNAT FAMILY (Enterococcusfaecalis) |
PF13527(Acetyltransf_9)PF13530(SCP2_2) | 4 | GLY A 93ILE A 75GLN A 114TYR A 138 | None | 1.05A | 5vlmC-2i00A:undetectable | 5vlmC-2i00A:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lnl | C-X-C CHEMOKINERECEPTOR TYPE 1 (Homo sapiens) |
PF00001(7tm_1) | 4 | GLN A 176ILE A 283GLN A 271TYR A 258 | None | 0.87A | 5vlmC-2lnlA:undetectable | 5vlmC-2lnlA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qr4 | PEPTIDASE M3B,OLIGOENDOPEPTIDASE F (Enterococcusfaecium) |
PF01432(Peptidase_M3)PF08439(Peptidase_M3_N) | 4 | GLN A 124ILE A 117GLN A 144TRP A 126 | None | 1.10A | 5vlmC-2qr4A:3.2 | 5vlmC-2qr4A:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vbf | BRANCHED-CHAINALPHA-KETOACIDDECARBOXYLASE (Lactococcuslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLN A 415GLY A 413ILE A 396ASP A 57 | GLN A 415 ( 0.6A)GLY A 413 ( 0.0A)ILE A 396 ( 0.7A)ASP A 57 ( 0.5A) | 1.16A | 5vlmC-2vbfA:undetectable | 5vlmC-2vbfA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vca | ALPHA-N-ACETYLGLUCOSAMINIDASE (Clostridiumperfringens) |
PF00754(F5_F8_type_C)PF05089(NAGLU)PF12971(NAGLU_N)PF12972(NAGLU_C) | 4 | GLN A 370GLY A 412ILE A 428TYR A 445 | None | 1.09A | 5vlmC-2vcaA:1.8 | 5vlmC-2vcaA:12.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vyc | BIODEGRADATIVEARGININEDECARBOXYLASE (Escherichiacoli) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | GLN A 577GLY A 280ILE A 282TYR A 655 | None | 1.12A | 5vlmC-2vycA:undetectable | 5vlmC-2vycA:12.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzm | ALDO-KETO REDUCTASE (Mycolicibacteriumsmegmatis) |
PF00248(Aldo_ket_red) | 4 | GLN A 89GLY A 119GLN A 178TRP A 117 | None | 1.10A | 5vlmC-2wzmA:undetectable | 5vlmC-2wzmA:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x3l | ORN/LYS/ARGDECARBOXYLASE FAMILYPROTEIN (Staphylococcusaureus) |
PF01276(OKR_DC_1)PF03711(OKR_DC_1_C) | 4 | GLN A 309GLY A 305ILE A 298TRP A 311 | None | 1.05A | 5vlmC-2x3lA:undetectable | 5vlmC-2x3lA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d3f | YVGN PROTEIN (Bacillussubtilis) |
PF00248(Aldo_ket_red) | 4 | GLN A 85GLY A 115GLN A 172TRP A 113 | NoneNoneNoneNDP A 1 ( 4.2A) | 1.06A | 5vlmC-3d3fA:undetectable | 5vlmC-3d3fA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f6u | VITAMIN K-DEPENDENTPROTEIN C HEAVYCHAIN (Homo sapiens) |
PF00089(Trypsin) | 4 | GLY H 226ILE H 158GLN H 30ASP H 194 | 0G6 H 1 ( 3.9A)NoneNoneNone | 0.98A | 5vlmC-3f6uH:undetectable | 5vlmC-3f6uH:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if6 | OXA-46 OXACILLINASE (Pseudomonasaeruginosa) |
PF00905(Transpeptidase) | 4 | ILE C 76GLN C 190TRP C 223TYR C 146 | KCX C 75 ( 4.4A)NoneNoneNone | 1.01A | 5vlmC-3if6C:undetectable | 5vlmC-3if6C:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n23 | SODIUM/POTASSIUM-TRANSPORTING ATPASESUBUNIT ALPHA-1 (Sus scrofa) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF13246(Cation_ATPase) | 4 | GLY A 542ILE A 620GLN A 376ASP A 586 | None | 1.17A | 5vlmC-3n23A:undetectable | 5vlmC-3n23A:11.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p27 | ELONGATION FACTOR 1ALPHA-LIKE PROTEIN (Saccharomycescerevisiae) |
PF00009(GTP_EFTU)PF03143(GTP_EFTU_D3) | 4 | GLY A 353ILE A 362ASP A 190TYR A 189 | GDP A 663 (-3.6A)NoneNoneNone | 0.97A | 5vlmC-3p27A:undetectable | 5vlmC-3p27A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r08 | MOUSE ANTI-MOUSECD3EPSILON ANTIBODY2C11 LIGHT CHAIN (Cricetulusmigratorius) |
PF07654(C1-set)PF07686(V-set) | 4 | GLY L 66ILE L 29GLN L 89TYR L 50 | None | 1.05A | 5vlmC-3r08L:undetectable | 5vlmC-3r08L:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r0m | LLAMA VHH A12 (Lama glama) |
PF07686(V-set) | 4 | GLY A 35GLN A 3ASP A 102TYR A 101 | None | 1.11A | 5vlmC-3r0mA:undetectable | 5vlmC-3r0mA:26.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r7t | ADENYLOSUCCINATESYNTHETASE (Campylobacterjejuni) |
PF00709(Adenylsucc_synt) | 4 | GLN A 220GLY A 221ILE A 240TYR A 313 | None | 0.80A | 5vlmC-3r7tA:undetectable | 5vlmC-3r7tA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5q | PUTATIVEGLYCOSYLHYDROLASE (Parabacteroidesdistasonis) |
PF06439(DUF1080) | 4 | GLN A 60ILE A 98TRP A 63TYR A 127 | None | 1.09A | 5vlmC-3s5qA:undetectable | 5vlmC-3s5qA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqe | MALONYL-COA-[ACYL-CARRIER-PROTEIN]TRANSACYLASE (Coxiellaburnetii) |
PF00698(Acyl_transf_1) | 4 | GLN A 12GLY A 13ILE A 195GLN A 167 | GLY A 314 (-4.0A)NoneNoneNone | 1.15A | 5vlmC-3tqeA:undetectable | 5vlmC-3tqeA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqi | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Coxiellaburnetii) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 4 | GLN A 254GLY A 226ILE A 221TRP A 330 | None | 1.16A | 5vlmC-3tqiA:undetectable | 5vlmC-3tqiA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w9h | ACRIFLAVINERESISTANCE PROTEIN B (Escherichiacoli) |
PF00873(ACR_tran) | 4 | GLN A1000GLY A 994ILE A 335ASP A 633 | None | 1.11A | 5vlmC-3w9hA:undetectable | 5vlmC-3w9hA:10.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zcw | KINESIN-LIKE PROTEINKIF11 (Homo sapiens) |
PF00225(Kinesin) | 4 | GLY A 217ILE A 136GLN A 78TRP A 127 | 4A2 A1367 (-3.3A)4A2 A1367 (-3.4A)NoneNone | 0.83A | 5vlmC-3zcwA:undetectable | 5vlmC-3zcwA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuk | ENDOPEPTIDASE,PEPTIDASE FAMILY M13 (Mycobacteriumtuberculosis) |
PF01431(Peptidase_M13)PF05649(Peptidase_M13_N) | 4 | GLY A 492ILE A 487GLN A 602TYR A 484 | NoneNonePEG A1667 ( 4.6A)None | 1.14A | 5vlmC-3zukA:2.1 | 5vlmC-3zukA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aef | NEOPULLULANASE(ALPHA-AMYLASE II) (Pyrococcusfuriosus) |
PF00128(Alpha-amylase)PF02903(Alpha-amylase_N)PF16561(AMPK1_CBM) | 4 | GLY A 407ILE A 435TRP A 203TYR A 257 | None | 1.14A | 5vlmC-4aefA:undetectable | 5vlmC-4aefA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4am3 | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE (Caulobactervibrioides) |
PF00013(KH_1)PF01138(RNase_PH)PF03725(RNase_PH_C)PF03726(PNPase) | 4 | GLN A 213GLY A 150ILE A 219TRP A 11 | None | 1.16A | 5vlmC-4am3A:2.9 | 5vlmC-4am3A:13.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0n | POLYKETIDE SYNTHASEIII (Ectocarpussiliculosus) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | GLN A 342GLY A 346ILE A 307TRP A 328 | None | 1.11A | 5vlmC-4b0nA:undetectable | 5vlmC-4b0nA:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | GLN A1128GLY A1123ILE A 509ASP A 430 | None | 1.13A | 5vlmC-4bedA:undetectable | 5vlmC-4bedA:8.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dji | PROBABLEGLUTAMATE/GAMMA-AMINOBUTYRATE ANTIPORTER (Escherichiacoli) |
PF13520(AA_permease_2) | 4 | GLN A 345GLY A 102ILE A 305TYR A 30 | None | 1.14A | 5vlmC-4djiA:1.6 | 5vlmC-4djiA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eku | PROTEIN-TYROSINEKINASE 2-BETA (Homo sapiens) |
PF00373(FERM_M) | 4 | GLN A 355GLY A 285ILE A 348TYR A 265 | None | 1.17A | 5vlmC-4ekuA:undetectable | 5vlmC-4ekuA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4esq | SERINE/THREONINEPROTEIN KINASE (Mycobacteriumtuberculosis) |
PF14032(PknH_C) | 4 | GLN A 520GLY A 504GLN A 483ASP A 471 | NoneNoneNone TB A 703 (-3.1A) | 1.17A | 5vlmC-4esqA:undetectable | 5vlmC-4esqA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fzi | PROSTAGLANDIN FSYNTHASE (Trypanosomacruzi) |
PF00248(Aldo_ket_red) | 4 | GLN A 84GLY A 114GLN A 171TRP A 112 | NoneNoneNoneGLU A 301 (-4.1A) | 1.11A | 5vlmC-4fziA:undetectable | 5vlmC-4fziA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl6 | HYPOTHETICAL PROTEIN ([Ruminococcus]gnavus) |
PF16440(DUF5037) | 4 | GLY A 240ILE A 256GLN A 262TYR A 183 | None | 0.97A | 5vlmC-4gl6A:undetectable | 5vlmC-4gl6A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h1l | ANI2.3 TCR A CHAINANI2.3 TCR B CHAIN (Escherichiacoli;Escherichiacoli) |
PF07686(V-set)PF07686(V-set) | 4 | GLN G 5GLY H 40ILE G 102ASP H 57 | None | 1.01A | 5vlmC-4h1lG:undetectable | 5vlmC-4h1lG:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k0e | HEAVY METAL CATIONTRICOMPONENT EFFLUXPUMP ZNEA(CZCA-LIKE) (Cupriavidusmetallidurans) |
PF00873(ACR_tran) | 4 | GLN A 697GLY A 816GLN A 852ASP A 818 | None | 1.10A | 5vlmC-4k0eA:1.1 | 5vlmC-4k0eA:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k3c | OUTER MEMBRANEPROTEIN ASSEMBLYFACTOR BAMA ([Haemophilus]ducreyi) |
PF01103(Bac_surface_Ag)PF07244(POTRA) | 4 | GLY A 661ILE A 667GLN A 684ASP A 780 | None | 1.05A | 5vlmC-4k3cA:undetectable | 5vlmC-4k3cA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mu6 | KINECTIN 1 (KINESINRECEPTOR) (Legionellapneumophila) |
no annotation | 4 | GLN A 76GLY A 227ILE A 232GLN A 238 | None | 0.96A | 5vlmC-4mu6A:undetectable | 5vlmC-4mu6A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n03 | ABC-TYPEBRANCHED-CHAIN AMINOACID TRANSPORTSYSTEMS PERIPLASMICCOMPONENT-LIKEPROTEIN (Thermomonosporacurvata) |
PF13458(Peripla_BP_6) | 4 | GLN A 175GLY A 173ILE A 183TRP A 176 | None | 1.02A | 5vlmC-4n03A:undetectable | 5vlmC-4n03A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p48 | ANTIBODY SCFV 180 (Gallus gallus) |
PF07686(V-set) | 4 | GLY A 23GLN A 163ASP A 237TYR A 32 | None | 1.12A | 5vlmC-4p48A:undetectable | 5vlmC-4p48A:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rjk | ACETOLACTATESYNTHASE (Bacillussubtilis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLN A 247GLY A 422ILE A 398GLN A 487 | None | 1.00A | 5vlmC-4rjkA:undetectable | 5vlmC-4rjkA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwr | STAGE II SPORULATIONPROTEIN D (Bacillusanthracis) |
PF08486(SpoIID) | 4 | GLY A 301ILE A 315TRP A 205TYR A 320 | None | 1.10A | 5vlmC-4rwrA:undetectable | 5vlmC-4rwrA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tn5 | FRUCTOSE-LIKEPHOSPHOTRANSFERASEENZYME IIB COMPONENT3 (Escherichiacoli) |
PF02302(PTS_IIB) | 4 | GLN A 40GLY A 70ILE A 54GLN A 107 | None | 1.11A | 5vlmC-4tn5A:undetectable | 5vlmC-4tn5A:24.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tx2 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Actinoplanesteichomyceticus) |
PF00668(Condensation) | 4 | GLN B 21GLY B 300GLN B 364ASP B 146 | None | 1.16A | 5vlmC-4tx2B:undetectable | 5vlmC-4tx2B:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xae | FERULOYL COAORTHO-HYDROXYLASE 1 (Arabidopsisthaliana) |
PF03171(2OG-FeII_Oxy)PF14226(DIOX_N) | 4 | GLN A 44GLY A 231ASP A 150TYR A 151 | None | 1.03A | 5vlmC-4xaeA:undetectable | 5vlmC-4xaeA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylj | DUAL SPECIFICITYTYROSINE-PHOSPHORYLATION-REGULATEDKINASE 1A (Homo sapiens) |
PF00069(Pkinase) | 4 | GLN A 313GLY A 315ILE A 318GLN A 320 | None | 0.92A | 5vlmC-4yljA:undetectable | 5vlmC-4yljA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ylj | DUAL SPECIFICITYTYROSINE-PHOSPHORYLATION-REGULATEDKINASE 1A (Homo sapiens) |
PF00069(Pkinase) | 4 | GLY A 315ILE A 284GLN A 469ASP A 339 | NoneNoneSO4 A 504 (-3.7A)None | 1.14A | 5vlmC-4yljA:undetectable | 5vlmC-4yljA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z0t | OXIDOREDUCTASE,SHORT-CHAINDEHYDROGENASE/REDUCTASE FAMILY (Brucella ovis) |
PF00106(adh_short) | 4 | GLN A 197GLY A 188ILE A 19GLN A 211 | NoneNone BR A 304 (-4.5A)None | 0.77A | 5vlmC-4z0tA:undetectable | 5vlmC-4z0tA:24.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amp | CELLOBIOHYDROLASE I (Galactomycescandidus) |
PF00840(Glyco_hydro_7) | 4 | GLN A 190GLY A 205ILE A 183TRP A 192 | NAG A 702 (-3.7A)NAG A 701 ( 3.7A)NoneNone | 1.16A | 5vlmC-5ampA:undetectable | 5vlmC-5ampA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d68 | KREV INTERACTIONTRAPPED PROTEIN 1 (Homo sapiens) |
PF00373(FERM_M)PF13857(Ank_5) | 4 | GLN A 689GLY A 691ILE A 709GLN A 643 | None | 1.06A | 5vlmC-5d68A:undetectable | 5vlmC-5d68A:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f07 | PUTATIVE GLUTATHIONES-TRANSFERASE FAMILYPROTEIN (Populustrichocarpa) |
PF00043(GST_C)PF02798(GST_N) | 4 | GLY A 125ILE A 120GLN A 40ASP A 36 | NoneNoneGSH A 301 (-3.8A)None | 1.13A | 5vlmC-5f07A:undetectable | 5vlmC-5f07A:19.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fkc | BETA-FRUCTOFURANOSIDASE (Xanthophyllomycesdendrorhous) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 4 | GLN A 97GLY A 147GLN A 388TYR A 85 | FRU A3001 ( 3.5A)NoneNoneNone | 1.15A | 5vlmC-5fkcA:undetectable | 5vlmC-5fkcA:15.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fql | IDURONATE-2-SULFATASE (Homo sapiens) |
PF00884(Sulfatase) | 4 | GLN A 465GLY A 489ILE A 485GLN A 474 | None | 1.12A | 5vlmC-5fqlA:undetectable | 5vlmC-5fqlA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 4 | GLN A 227GLY A 228ILE A 271GLN A 199 | None | 1.11A | 5vlmC-5g5nA:undetectable | 5vlmC-5g5nA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtx | BUCKWHEATGLUTAREDOXIN (Polygonaceae) |
PF00462(Glutaredoxin) | 4 | GLN A 71GLY A 67ILE A 59GLN A 24 | None | 1.06A | 5vlmC-5gtxA:undetectable | 5vlmC-5gtxA:19.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h53 | SKELETAL MUSCLEMYOSIN HEAVY CHAINMYHC-EO/IIL (Oryctolaguscuniculus) |
PF00063(Myosin_head)PF02736(Myosin_N) | 4 | GLN A 448GLY A 216ILE A 223GLN A 194 | None | 1.16A | 5vlmC-5h53A:2.6 | 5vlmC-5h53A:13.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikk | HISTONE DEACETYLASECLR3 (Schizosaccharomycespombe) |
PF00850(Hist_deacetyl)PF09757(Arb2) | 4 | GLY A 325ILE A 235ASP A 332TYR A 367 | NoneNoneNoneEDO A 710 (-4.6A) | 1.06A | 5vlmC-5ikkA:undetectable | 5vlmC-5ikkA:15.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j8n | EXODEOXYRIBONUCLEASEIII (Methanosarcinamazei) |
PF03372(Exo_endo_phos) | 4 | GLN A 38GLY A 73ILE A 34TYR A 57 | None | 1.12A | 5vlmC-5j8nA:undetectable | 5vlmC-5j8nA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9p | PERIPLASMIC BINDINGPROTEIN (Agrobacteriumtumefaciens) |
PF13416(SBP_bac_8) | 4 | GLN A 240GLY A 236ILE A 224GLN A 219 | None | 0.99A | 5vlmC-5l9pA:undetectable | 5vlmC-5l9pA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mif | 'CARBOXYL ESTERASE 2 (Tubermelanosporum) |
PF07859(Abhydrolase_3) | 4 | GLN A 214GLY A 187ILE A 217TYR A 128 | None | 1.04A | 5vlmC-5mifA:undetectable | 5vlmC-5mifA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfq | EPOXIDE HYDROLASEBELONGING TOALPHA/BETA HYDROLASESUPERFAMILYMETAGENOMIC FROMTOMSK SAMPLE (metagenome) |
no annotation | 4 | GLN A 60GLY A 104ILE A 98TRP A 42 | None | 1.10A | 5vlmC-5nfqA:undetectable | 5vlmC-5nfqA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nlt | CVAA9A (Collariellavirescens) |
no annotation | 4 | GLY A 15ILE A 22GLN A 146TYR A 66 | None | 0.93A | 5vlmC-5nltA:undetectable | 5vlmC-5nltA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ov6 | PORPHOBILINOGENDEAMINASE (Bacillusmegaterium) |
PF01379(Porphobil_deam)PF03900(Porphobil_deamC) | 4 | GLN A 17ILE A 202GLN A 28TRP A 20 | None | 1.13A | 5vlmC-5ov6A:undetectable | 5vlmC-5ov6A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ti8 | AMINOTRANSFERASE (Pseudomonas sp.M1) |
PF00202(Aminotran_3) | 4 | GLN A 359GLY A 381ILE A 230GLN A 187 | None | 1.02A | 5vlmC-5ti8A:undetectable | 5vlmC-5ti8A:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tw7 | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Neisseriagonorrhoeae) |
PF00117(GATase)PF00958(GMP_synt_C)PF02540(NAD_synthase) | 4 | GLN A 244GLY A 216ILE A 211TRP A 321 | None | 1.12A | 5vlmC-5tw7A:undetectable | 5vlmC-5tw7A:16.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txv | ATP-DEPENDENTPROTEASE ATPASESUBUNIT HSLU (Escherichiacoli) |
PF00004(AAA)PF07724(AAA_2)PF10431(ClpB_D2-small) | 4 | GLN A 20GLY A 62ILE A 343GLN A 354 | NoneADP A 501 (-3.2A)ADP A 501 ( 4.5A)None | 1.04A | 5vlmC-5txvA:undetectable | 5vlmC-5txvA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgz | 26S PROTEASOMEREGULATORY SUBUNIT 726S PROTEASOMEREGULATORY SUBUNIT 4 (Homo sapiens;Homo sapiens) |
no annotationno annotation | 4 | GLY B 161ILE B 135GLN A 85ASP A 79 | None | 1.00A | 5vlmC-5vgzB:undetectable | 5vlmC-5vgzB:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vlg | REGULATORY PROTEINTETR ([Enterobacter]lignolyticus) |
no annotation | 5 | GLN A 71GLY A 88TRP A 125ASP A 163TYR A 166 | MGR A 300 ( 4.1A)MGR A 300 ( 2.9A)MGR A 300 (-3.5A)MGR A 300 (-3.5A)MGR A 300 (-3.0A) | 0.72A | 5vlmC-5vlgA:29.4 | 5vlmC-5vlgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vlg | REGULATORY PROTEINTETR ([Enterobacter]lignolyticus) |
no annotation | 6 | GLY A 88ILE A 98GLN A 105TRP A 125ASP A 163TYR A 166 | MGR A 300 ( 2.9A)MGR A 300 (-3.1A)MGR A 300 ( 3.0A)MGR A 300 (-3.5A)MGR A 300 (-3.5A)MGR A 300 (-3.0A) | 0.31A | 5vlmC-5vlgA:29.4 | 5vlmC-5vlgA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vmb | SERINEHYDROXYMETHYLTRANSFERASE (Acinetobacterbaumannii) |
PF00464(SHMT) | 5 | GLN A 295GLY A 312ILE A 302GLN A 325ASP A 307 | None | 1.07A | 5vlmC-5vmbA:undetectable | 5vlmC-5vmbA:17.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vnc | GLYCOGEN [STARCH]SYNTHASE ISOFORM 2 (Saccharomycescerevisiae) |
no annotation | 4 | GLY A 173ILE A 128TRP A 170TYR A 145 | None | 1.08A | 5vlmC-5vncA:undetectable | 5vlmC-5vncA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vzt | F-BOX ONLY PROTEIN31 (Homo sapiens) |
no annotation | 4 | GLN B 535GLY B 340ILE B 337TYR B 309 | NoneNoneDTT B 602 (-4.3A)DTT B 602 ( 4.9A) | 1.15A | 5vlmC-5vztB:undetectable | 5vlmC-5vztB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1t | PPKA-294 (Serratia sp.FS14) |
no annotation | 4 | GLY A 35ILE A 68GLN A 80TYR A 115 | None | 1.05A | 5vlmC-5x1tA:undetectable | 5vlmC-5x1tA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjj | MULTI DRUG EFFLUXTRANSPORTER (Camelina sativa) |
PF01554(MatE) | 4 | GLN A 459GLY A 397ILE A 401GLN A 443 | OLC A 501 ( 4.5A)NoneNoneNone | 1.06A | 5vlmC-5xjjA:undetectable | 5vlmC-5xjjA:18.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xwd | VL CHAIN OF 059-152VH CHAIN OF 059-152 (Homo sapiens;Homo sapiens) |
no annotationno annotation | 4 | GLY H 46ILE H 39GLN H 112TYR D 36 | None | 0.94A | 5vlmC-5xwdH:undetectable | 5vlmC-5xwdH:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y29 | INSECT GROUP IICHITINASE (Ostriniafurnacalis) |
no annotation | 4 | GLN A1922GLY A1925ILE A1943TYR A1902 | None | 1.06A | 5vlmC-5y29A:undetectable | 5vlmC-5y29A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6brs | PUTATIVE ZINCPROTEASE (Pectobacteriumatrosepticum) |
no annotation | 4 | GLN A 861GLY A 859ILE A 854GLN A 849 | None | 1.11A | 5vlmC-6brsA:undetectable | 5vlmC-6brsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c08 | ANTIBODY FAB HEAVYCHAIN (Mus musculus) |
no annotation | 4 | GLN A 111GLY A 8ILE A 20ASP A 18 | None | 1.13A | 5vlmC-6c08A:undetectable | 5vlmC-6c08A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d1w | POLYCYSTIN-2 (Homo sapiens) |
no annotation | 4 | GLN A 630ILE A 382GLN A 456TYR A 386 | None | 0.96A | 5vlmC-6d1wA:undetectable | 5vlmC-6d1wA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6egt | GLYCOPROTEIN (Rift Valleyfeverphlebovirus) |
no annotation | 4 | GLY A1058ILE A1052GLN A1084TYR A1099 | None | 1.14A | 5vlmC-6egtA:undetectable | 5vlmC-6egtA:13.87 |