SIMILAR PATTERNS OF AMINO ACIDS FOR 5VKQ_A_PCFA1804
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mpx | ALPHA-AMINO ACIDESTER HYDROLASE (Xanthomonascitri) |
PF02129(Peptidase_S15)PF08530(PepX_C) | 4 | TRP A 404THR A 573ASN A 575LEU A 469 | None | 1.47A | 5vkqA-1mpxA:0.05vkqB-1mpxA:0.0 | 5vkqA-1mpxA:16.875vkqB-1mpxA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yew | PARTICULATE METHANEMONOOXYGENASE, ASUBUNITPARTICULATE METHANEMONOOXYGENASESUBUNIT C2 (Methylococcuscapsulatus;Methylococcuscapsulatus) |
PF02461(AMO)PF04896(AmoC) | 4 | THR B 112ASN B 107TRP C 159LEU C 78 | None | 1.33A | 5vkqA-1yewB:2.25vkqB-1yewB:1.6 | 5vkqA-1yewB:9.155vkqB-1yewB:9.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cda | GLUCOSEDEHYDROGENASE (Sulfolobussolfataricus) |
PF08240(ADH_N)PF16912(Glu_dehyd_C) | 4 | TRP A 365THR A 33TRP A 128LEU A 135 | None | 1.25A | 5vkqA-2cdaA:0.95vkqB-2cdaA:0.9 | 5vkqA-2cdaA:11.975vkqB-2cdaA:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nq5 | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Streptococcusmutans) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | THR A 418ASN A 712TRP A 710LEU A 410 | None | 1.39A | 5vkqA-2nq5A:2.15vkqB-2nq5A:1.2 | 5vkqA-2nq5A:18.695vkqB-2nq5A:18.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vbi | PYRUVATEDECARBOXYLASE (Acetobacterpasteurianus) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | TRP A 295THR A 292ASN A 288LEU A 280 | None | 1.50A | 5vkqA-2vbiA:0.05vkqB-2vbiA:0.0 | 5vkqA-2vbiA:15.615vkqB-2vbiA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 4 | THR A 694ASN A 714TRP A 717LEU A 648 | None | 1.40A | 5vkqA-2vsaA:undetectable5vkqB-2vsaA:undetectable | 5vkqA-2vsaA:18.855vkqB-2vsaA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ac1 | ENDO-N-ACETYL-BETA-D-GLUCOSAMINIDASE (Trichodermareesei) |
PF00704(Glyco_hydro_18) | 4 | THR X 72ASN X 70TRP X 69LEU X 55 | NoneNAG X 302 (-1.8A)NoneNone | 1.48A | 5vkqA-4ac1X:0.65vkqB-4ac1X:0.6 | 5vkqA-4ac1X:9.935vkqB-4ac1X:9.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | THR B 606ASN B 638TRP B 593LEU B 569 | None | 1.37A | 5vkqA-4f92B:1.85vkqB-4f92B:1.7 | 5vkqA-4f92B:23.495vkqB-4f92B:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i3g | BETA-GLUCOSIDASE (Streptomycesvenezuelae) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | THR A 611ASN A 610TRP A 630LEU A 654 | None | 1.46A | 5vkqA-4i3gA:0.05vkqB-4i3gA:0.2 | 5vkqA-4i3gA:20.485vkqB-4i3gA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4inz | SOLUBLE EPOXIDEHYDROLASE (Bacillusmegaterium) |
PF00561(Abhydrolase_1) | 4 | TRP A 235ASN A 246TRP A 104LEU A 227 | None | 1.30A | 5vkqA-4inzA:0.05vkqB-4inzA:0.0 | 5vkqA-4inzA:9.975vkqB-4inzA:9.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o6x | ANKYRIN-3 (Homo sapiens) |
PF00531(Death) | 4 | THR A 64ASN A 62TRP A 55LEU A 22 | None | 1.39A | 5vkqA-4o6xA:undetectable5vkqB-4o6xA:undetectable | 5vkqA-4o6xA:5.445vkqB-4o6xA:5.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a5c | LRRTM (syntheticconstruct) |
PF13855(LRR_8) | 4 | TRP A 207THR A 230ASN A 255LEU A 237 | None | 1.46A | 5vkqA-5a5cA:undetectable5vkqB-5a5cA:undetectable | 5vkqA-5a5cA:12.515vkqB-5a5cA:12.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a8v | POLYHEDRIN (Cypovirus 5) |
no annotation | 4 | THR A 33ASN A 31TRP A 48LEU A 58 | None | 1.32A | 5vkqA-5a8vA:undetectable5vkqB-5a8vA:undetectable | 5vkqA-5a8vA:9.415vkqB-5a8vA:9.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5d | INNER MEMBRANEPROTEIN YEJM (Salmonellaenterica) |
PF00884(Sulfatase)PF11893(DUF3413) | 4 | THR A 535ASN A 548TRP A 464LEU A 469 | None | 1.25A | 5vkqA-5i5dA:undetectable5vkqB-5i5dA:undetectable | 5vkqA-5i5dA:16.785vkqB-5i5dA:16.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lh9 | OMEGA TRANSAMINASE (Pseudomonas sp.) |
PF00202(Aminotran_3) | 4 | TRP A 182THR A 180ASN A 146LEU A 219 | None | 1.47A | 5vkqA-5lh9A:undetectable5vkqB-5lh9A:undetectable | 5vkqA-5lh9A:14.545vkqB-5lh9A:14.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nmi | CYTOCHROME B (Bos taurus) |
PF00032(Cytochrom_B_C)PF00033(Cytochrome_B) | 4 | TRP C 165THR C 144ASN C 148LEU C 262 | None | 1.46A | 5vkqA-5nmiC:4.15vkqB-5nmiC:4.1 | 5vkqA-5nmiC:11.845vkqB-5nmiC:11.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 4 | THR A 472ASN A 760TRP A 761LEU A 752 | None | 1.35A | 5vkqA-6d95A:1.05vkqB-6d95A:0.9 | 5vkqA-6d95A:undetectable5vkqB-6d95A:undetectable |