SIMILAR PATTERNS OF AMINO ACIDS FOR 5VEU_H_RITH602_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bkd SON OF SEVENLESS-1

(Homo sapiens) 		PF00617
(RasGEF)
PF00618
(RasGEF_N) 		4 PHE S 929
PHE S 930
LEU S 934
LEU S 919
 None
 1.35A 5veuH-1bkdS:
0.0		 5veuH-1bkdS:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cj2 PROTEIN
(P-HYDROXYBENZOATE
HYDROXYLASE)

(Pseudomonas
fluorescens) 		PF01494
(FAD_binding_3) 		4 ARG A 166
PHE A 282
LEU A 281
LEU A 333
 None
 1.18A 5veuH-1cj2A:
undetectable		 5veuH-1cj2A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ej8 LYS7

(Saccharomyces
cerevisiae) 		PF00080
(Sod_Cu) 		4 PHE A 116
PHE A 175
LEU A 115
LEU A 103
 None
 0.88A 5veuH-1ej8A:
0.0		 5veuH-1ej8A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gk2 HISTIDINE
AMMONIA-LYASE

(Pseudomonas
putida) 		PF00221
(Lyase_aromatic) 		4 ARG A 355
PHE A 256
LEU A 260
LEU A 497
 None
 1.10A 5veuH-1gk2A:
1.3		 5veuH-1gk2A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hkw DIAMINOPIMELATE
DECARBOXYLASE

(Mycobacterium
tuberculosis) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ARG A 430
PHE A  43
LEU A 433
LEU A  34
 None
 1.11A 5veuH-1hkwA:
0.0		 5veuH-1hkwA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jdp ATRIAL NATRIURETIC
PEPTIDE CLEARANCE
RECEPTOR

(Homo sapiens) 		PF01094
(ANF_receptor) 		4 PHE A 371
PHE A 391
LEU A 280
LEU A 146
 None
 1.30A 5veuH-1jdpA:
0.0		 5veuH-1jdpA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqo PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Zea mays) 		PF00311
(PEPcase) 		4 ARG A 861
PHE A 742
LEU A 788
LEU A 848
 None
 1.04A 5veuH-1jqoA:
0.0		 5veuH-1jqoA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m6u NDT80 PROTEIN

(Saccharomyces
cerevisiae) 		PF05224
(NDT80_PhoG) 		4 PHE A 310
PHE A 153
LEU A 279
LEU A 148
 None
 1.30A 5veuH-1m6uA:
undetectable		 5veuH-1m6uA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mnn NDT80 PROTEIN

(Saccharomyces
cerevisiae) 		PF05224
(NDT80_PhoG) 		4 PHE A 310
PHE A 153
LEU A 279
LEU A 148
 None
 1.37A 5veuH-1mnnA:
0.0		 5veuH-1mnnA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)

(Homo sapiens) 		PF00104
(Hormone_recep) 		4 ARG B 563
PHE B 443
LEU B 446
LEU B 570
 None
 1.32A 5veuH-1ovlB:
undetectable		 5veuH-1ovlB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qb4 PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Escherichia
coli) 		PF00311
(PEPcase) 		4 ARG A 799
PHE A 682
LEU A 728
LEU A 786
 None
 0.95A 5veuH-1qb4A:
undetectable		 5veuH-1qb4A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s3k HU3S193 FAB
FRAGMENT, HEAVY
CHAIN

(Homo sapiens;
Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE H  95
PHE H 106
LEU H  45
LEU H  81
 None
 0.99A 5veuH-1s3kH:
undetectable		 5veuH-1s3kH:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1smr RENIN

(Mus musculus) 		PF00026
(Asp) 		4 PHE A 101
PHE A  71
LEU A  84
LEU A 121
 None
 1.28A 5veuH-1smrA:
undetectable		 5veuH-1smrA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0h VOLTAGE-GATED
CALCIUM CHANNEL
SUBUNIT BETA2A

(Rattus
norvegicus) 		PF00625
(Guanylate_kin) 		4 PHE B 250
PHE B 252
LEU B 249
LEU B 315
 None
 1.37A 5veuH-1t0hB:
undetectable		 5veuH-1t0hB:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tz7 4-ALPHA-GLUCANOTRANS
FERASE

(Aquifex
aeolicus) 		PF02446
(Glyco_hydro_77) 		4 PHE A 282
PHE A 280
LEU A 283
LEU A   7
 None
 0.94A 5veuH-1tz7A:
undetectable		 5veuH-1tz7A:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uan HYPOTHETICAL PROTEIN
TT1542

(Thermus
thermophilus) 		PF02585
(PIG-L) 		4 ARG A  93
PHE A  66
LEU A   2
LEU A  37
 None
 1.18A 5veuH-1uanA:
undetectable		 5veuH-1uanA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		4 PHE A 132
PHE A  60
LEU A 131
LEU A 155
 None
 1.07A 5veuH-1ulvA:
undetectable		 5veuH-1ulvA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xdv SON OF SEVENLESS
PROTEIN HOMOLOG 1

(Homo sapiens) 		PF00169
(PH)
PF00617
(RasGEF)
PF00618
(RasGEF_N)
PF00621
(RhoGEF) 		4 PHE A 929
PHE A 930
LEU A 934
LEU A 919
 None
 1.35A 5veuH-1xdvA:
undetectable		 5veuH-1xdvA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y5e MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
B

(Bacillus cereus) 		PF00994
(MoCF_biosynth) 		4 PHE A 138
PHE A 109
LEU A 154
LEU A  36
 None
 1.27A 5veuH-1y5eA:
undetectable		 5veuH-1y5eA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7l UBIQUITIN-ACTIVATING
ENZYME E1 1

(Mus musculus) 		PF10585
(UBA_e1_thiolCys) 		4 PHE A 861
PHE A 857
LEU A 771
LEU A 762
 None
 1.28A 5veuH-1z7lA:
undetectable		 5veuH-1z7lA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a38 TITIN

(Homo sapiens) 		PF07679
(I-set) 		4 ARG A 139
PHE A 150
LEU A 161
LEU A 192
 None
 1.30A 5veuH-2a38A:
undetectable		 5veuH-2a38A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e8g HYPOTHETICAL PROTEIN
PH0536

(Pyrococcus
horikoshii) 		PF01588
(tRNA_bind) 		4 PHE A  20
PHE A 112
LEU A  19
LEU A  71
 None
 1.13A 5veuH-2e8gA:
undetectable		 5veuH-2e8gA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvl ALDO-KETO REDUCTASE
FAMILY 1, MEMBER C4

(Homo sapiens) 		PF00248
(Aldo_ket_red) 		4 PHE A  89
PHE A  90
LEU A  85
LEU A 129
 None
 1.30A 5veuH-2fvlA:
undetectable		 5veuH-2fvlA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hz7 GLUTAMINYL-TRNA
SYNTHETASE

(Deinococcus
radiodurans) 		PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C) 		4 ARG A  96
PHE A  72
PHE A  92
LEU A  89
 None
 1.35A 5veuH-2hz7A:
undetectable		 5veuH-2hz7A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lao LYSINE, ARGININE,
ORNITHINE-BINDING
PROTEIN

(Salmonella
enterica) 		PF00497
(SBP_bac_3) 		4 ARG A  77
PHE A  52
LEU A  55
LEU A  87
 None
 1.31A 5veuH-2laoA:
undetectable		 5veuH-2laoA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2llg UNCHARACTERIZED
PROTEIN

(Enterococcus
faecalis) 		PF16729
(DUF5067) 		4 ARG A  15
PHE A  64
PHE A 124
LEU A  17
 None
 1.31A 5veuH-2llgA:
undetectable		 5veuH-2llgA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r66 GLYCOSYL
TRANSFERASE, GROUP 1

(Halothermothrix
orenii) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		4 ARG A 442
PHE A 371
LEU A 373
LEU A 397
 None
 1.36A 5veuH-2r66A:
undetectable		 5veuH-2r66A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rds FE(II)/ALPHA-KETOGL
UTARATE DEPENDENT
HYDROXYLASE
1-DEOXYPENTALENIC
ACID 11-BETA
HYDROXYLASE

(Streptomyces
avermitilis) 		PF05721
(PhyH) 		4 ARG A 150
PHE A  32
LEU A 218
LEU A  15
 None
 0.95A 5veuH-2rdsA:
undetectable		 5veuH-2rdsA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2stt ETS1

(Homo sapiens) 		PF00178
(Ets) 		4 ARG A  64
PHE A  30
LEU A  31
LEU A  16
 None
 1.28A 5veuH-2sttA:
undetectable		 5veuH-2sttA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynm LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Prochlorococcus
marinus) 		PF00148
(Oxidored_nitro) 		4 PHE C  98
PHE C  33
LEU C  97
LEU C  19
 None
None
None
SF4  C1413 (-4.3A)
 1.01A 5veuH-2ynmC:
undetectable		 5veuH-2ynmC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zq5 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		PF13469
(Sulfotransfer_3) 		4 ARG A 295
PHE A 300
PHE A 237
LEU A 384
 None
 1.26A 5veuH-2zq5A:
undetectable		 5veuH-2zq5A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zyj ALPHA-AMINODIPATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 PHE A  37
PHE A 351
LEU A 386
LEU A  28
 None
 1.24A 5veuH-2zyjA:
undetectable		 5veuH-2zyjA:
24.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aeu LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Rhodobacter
capsulatus) 		PF00148
(Oxidored_nitro) 		4 PHE A 107
PHE A  42
LEU A 106
LEU A  28
 None
None
None
SF4  A 425 (-4.1A)
 1.09A 5veuH-3aeuA:
undetectable		 5veuH-3aeuA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d00 TUNGSTEN
FORMYLMETHANOFURAN
DEHYDROGENASE
SUBUNIT E

(Syntrophus
aciditrophicus) 		PF02663
(FmdE) 		4 PHE A 100
PHE A  84
LEU A 101
LEU A  88
 None
 1.37A 5veuH-3d00A:
undetectable		 5veuH-3d00A:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dsh INTERFERON
REGULATORY FACTOR 5

(Homo sapiens) 		PF10401
(IRF-3) 		4 PHE A 420
PHE A 372
LEU A 417
LEU A 424
 None
 1.00A 5veuH-3dshA:
undetectable		 5veuH-3dshA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fg7 VILLIN-1

(Homo sapiens) 		PF00626
(Gelsolin) 		4 PHE A 622
PHE A 650
LEU A 621
LEU A 632
 None
 1.22A 5veuH-3fg7A:
undetectable		 5veuH-3fg7A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hm8 HEXOKINASE-3

(Homo sapiens) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 ARG A 644
PHE A 608
LEU A 642
LEU A 604
 None
 1.26A 5veuH-3hm8A:
1.4		 5veuH-3hm8A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hoa THERMOSTABLE
CARBOXYPEPTIDASE 1

(Thermus
thermophilus) 		PF02074
(Peptidase_M32) 		4 ARG A 382
PHE A 427
LEU A 376
LEU A 168
 None
 1.26A 5veuH-3hoaA:
undetectable		 5veuH-3hoaA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kcu PROBABLE FORMATE
TRANSPORTER 1

(Escherichia
coli) 		PF01226
(Form_Nir_trans) 		4 PHE A  75
PHE A  51
LEU A  77
LEU A  69
 None
 0.83A 5veuH-3kcuA:
1.8		 5veuH-3kcuA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kly PUTATIVE FORMATE
TRANSPORTER 1

(Vibrio cholerae) 		PF01226
(Form_Nir_trans) 		4 PHE A  74
PHE A  50
LEU A  76
LEU A  68
 None
 0.93A 5veuH-3klyA:
1.8		 5veuH-3klyA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ky9 PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00130
(C1_1)
PF00169
(PH)
PF00621
(RhoGEF)
PF11971
(CAMSAP_CH) 		4 ARG A 537
PHE A 277
LEU A 278
LEU A 334
 None
 1.29A 5veuH-3ky9A:
undetectable		 5veuH-3ky9A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldr FRUCTOSYLTRANSFERASE

(Aspergillus
japonicus) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 PHE A 628
PHE A 627
LEU A 489
LEU A 592
 None
 1.15A 5veuH-3ldrA:
undetectable		 5veuH-3ldrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lij CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 4
CALMODULIN LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase)
PF13499
(EF-hand_7) 		4 ARG A  88
PHE A 127
LEU A 124
LEU A  58
 None
 1.33A 5veuH-3lijA:
undetectable		 5veuH-3lijA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3psf TRANSCRIPTION
ELONGATION FACTOR
SPT6

(Saccharomyces
cerevisiae) 		PF14635
(HHH_7)
PF14639
(YqgF)
PF14641
(HTH_44)
PF14878
(DLD) 		4 ARG A1066
PHE A1056
LEU A1037
LEU A1016
 None
 1.10A 5veuH-3psfA:
undetectable		 5veuH-3psfA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qh6 CT296

(Chlamydia
trachomatis) 		PF16802
(DUF5070) 		4 PHE A 125
PHE A 126
LEU A 124
LEU A  90
 None
 1.11A 5veuH-3qh6A:
undetectable		 5veuH-3qh6A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)

(Doryteuthis
pealeii) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		4 ARG A 756
PHE A 614
LEU A 611
LEU A 319
 None
 1.36A 5veuH-3qr1A:
undetectable		 5veuH-3qr1A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3re1 UROPORPHYRINOGEN-III
SYNTHETASE

(Pseudomonas
syringae group
genomosp. 3) 		PF02602
(HEM4) 		4 ARG A 121
PHE A  87
LEU A 116
LEU A  98
 None
 1.29A 5veuH-3re1A:
undetectable		 5veuH-3re1A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tig TTL PROTEIN

(Xenopus
tropicalis) 		PF03133
(TTL) 		4 PHE A 263
PHE A 264
LEU A 221
LEU A 346
 None
 1.26A 5veuH-3tigA:
undetectable		 5veuH-3tigA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vxi DYP

(Bjerkandera
adusta) 		PF04261
(Dyp_perox) 		4 PHE A 429
PHE A 428
LEU A 430
LEU A  79
 None
 1.08A 5veuH-3vxiA:
undetectable		 5veuH-3vxiA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wfz LACTO-N-BIOSE
PHOSPHORYLASE

(Bifidobacterium
longum) 		PF09508
(Lact_bio_phlase)
PF17385
(LBP_M)
PF17386
(LBP_C) 		4 ARG A 485
PHE A 539
LEU A 444
LEU A 684
 None
 0.97A 5veuH-3wfzA:
undetectable		 5veuH-3wfzA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wpe TOLL-LIKE RECEPTOR 9

(Bos taurus) 		PF13516
(LRR_6)
PF13855
(LRR_8) 		4 PHE A 418
PHE A 473
LEU A 475
LEU A 392
 None
 1.36A 5veuH-3wpeA:
undetectable		 5veuH-3wpeA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgb PHOSPHOENOLPYRUVATE
CARBOXYLASE

(Flaveria
pringlei) 		PF00311
(PEPcase) 		4 ARG A 855
PHE A 736
LEU A 782
LEU A 842
 None
 1.05A 5veuH-3zgbA:
1.3		 5veuH-3zgbA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo9 TREHALOSE
SYNTHASE/AMYLASE
TRES

(Mycolicibacterium
smegmatis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 ARG A 376
PHE A 391
LEU A 380
LEU A 473
 None
 1.36A 5veuH-3zo9A:
undetectable		 5veuH-3zo9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cgr PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		PF00440
(TetR_N) 		4 ARG A 165
PHE A 226
LEU A 183
LEU A 220
 None
 1.21A 5veuH-4cgrA:
undetectable		 5veuH-4cgrA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e45 FANCONI ANEMIA GROUP
M PROTEIN

(Homo sapiens) 		PF16783
(FANCM-MHF_bd) 		4 ARG E 693
PHE E 679
PHE E 685
LEU E 680
 None
 1.36A 5veuH-4e45E:
undetectable		 5veuH-4e45E:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ipe TNF
RECEPTOR-ASSOCIATED
PROTEIN 1

(Danio rerio) 		PF00183
(HSP90)
PF13589
(HATPase_c_3) 		4 ARG A 464
PHE A 456
LEU A 482
LEU A 540
 None
 1.22A 5veuH-4ipeA:
undetectable		 5veuH-4ipeA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu2 CELLULOSE-BINDING
PROTEIN

(Ruminococcus
flavefaciens) 		no annotation 4 PHE B  24
PHE B  26
LEU B 179
LEU B 190
 None
 1.12A 5veuH-4iu2B:
undetectable		 5veuH-4iu2B:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ntj P2Y PURINOCEPTOR
12,SOLUBLE
CYTOCHROME B562,P2Y
PURINOCEPTOR 12

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		4 PHE A  77
PHE A  37
LEU A  40
LEU A  82
 None
 1.35A 5veuH-4ntjA:
0.0		 5veuH-4ntjA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5y MATERNAL PROTEIN
TUDOR

(Drosophila
melanogaster) 		PF00567
(TUDOR) 		4 ARG A2478
PHE A2501
PHE A2483
LEU A2500
 None
 1.31A 5veuH-4q5yA:
undetectable		 5veuH-4q5yA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt6 HEME/HEMOPEXIN-BINDI
NG PROTEIN

(Haemophilus
influenzae) 		PF05860
(Haemagg_act) 		4 PHE A 415
PHE A 416
LEU A 439
LEU A 528
 None
 1.34A 5veuH-4rt6A:
undetectable		 5veuH-4rt6A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru0 PUTATIVE
BRANCHED-CHAIN AMINO
ACID ABC
TRANSPORTER,
PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN

(Pseudomonas
protegens) 		PF13458
(Peripla_BP_6) 		4 PHE A  94
PHE A  33
LEU A  35
LEU A 128
 None
 1.20A 5veuH-4ru0A:
undetectable		 5veuH-4ru0A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbd BSHC

(Bacillus
subtilis) 		PF10079
(BshC) 		4 PHE A 285
PHE A 327
LEU A 284
LEU A 307
 None
 1.26A 5veuH-4wbdA:
undetectable		 5veuH-4wbdA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4whm UDP-GLUCOSE:ANTHOCYA
NIDIN
3-O-GLUCOSYLTRANSFER
ASE

(Clitoria
ternatea) 		PF00201
(UDPGT) 		4 PHE A  50
PHE A  48
LEU A  18
LEU A 246
 None
 1.37A 5veuH-4whmA:
undetectable		 5veuH-4whmA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wlp UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE ISOZYME L5

(Homo sapiens) 		PF01088
(Peptidase_C12) 		4 PHE A  18
PHE A 143
LEU A  21
LEU A 277
 None
 1.35A 5veuH-4wlpA:
undetectable		 5veuH-4wlpA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y7o TYPE VI SECRETION
SYSTEM PROTEIN VASD

(Escherichia
coli) 		PF12790
(T6SS-SciN) 		4 PHE C 106
PHE C  60
LEU C  54
LEU C 149
 None
 1.20A 5veuH-4y7oC:
undetectable		 5veuH-4y7oC:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9l PROTEIN ACDH-11,
ISOFORM B

(Caenorhabditis
elegans) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M) 		4 ARG A 346
PHE A 151
LEU A 152
LEU A 453
 None
 1.05A 5veuH-4y9lA:
undetectable		 5veuH-4y9lA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z64 PHYTOSULFOKINE
RECEPTOR 1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 PHE A 272
PHE A 273
LEU A 270
LEU A 321
 None
 1.30A 5veuH-4z64A:
undetectable		 5veuH-4z64A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zow MULTIDRUG
TRANSPORTER MDFA

(Escherichia
coli) 		PF07690
(MFS_1) 		4 PHE A 230
PHE A 361
LEU A 233
LEU A 334
 None
 1.35A 5veuH-4zowA:
undetectable		 5veuH-4zowA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zti POLYMERASE COFACTOR
VP35,NUCLEOPROTEIN

(Zaire
ebolavirus) 		PF02097
(Filo_VP35)
PF05505
(Ebola_NP) 		4 ARG A 240
PHE A 296
LEU A 158
LEU A 245
 None
 1.09A 5veuH-4ztiA:
undetectable		 5veuH-4ztiA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b7i CRISPR-ASSOCIATED
NUCLEASE/HELICASE
CAS3 SUBTYPE
I-F/YPEST

(Pseudomonas
aeruginosa) 		no annotation 4 ARG A 916
PHE A 892
PHE A 887
LEU A 932
 None
 1.33A 5veuH-5b7iA:
undetectable		 5veuH-5b7iA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eeb ALDEHYDE
DEHYDROGENASE

(Pyrobaculum
ferrireducens) 		PF00171
(Aldedh) 		4 PHE A 363
PHE A 364
LEU A 330
LEU A 314
 None
 1.32A 5veuH-5eebA:
undetectable		 5veuH-5eebA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fdn PHOSPHOENOLPYRUVATE
CARBOXYLASE 3

(Arabidopsis
thaliana) 		PF00311
(PEPcase) 		4 ARG A 858
PHE A 739
LEU A 785
LEU A 845
 None
 1.10A 5veuH-5fdnA:
1.5		 5veuH-5fdnA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqd CASEIN KINASE I
ISOFORM ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 PHE C 154
PHE C 142
LEU C 153
LEU C  67
 None
 1.26A 5veuH-5fqdC:
undetectable		 5veuH-5fqdC:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2t TREHALOSE SYNTHASE

(Thermomonospora
curvata) 		no annotation 4 ARG A 363
PHE A 378
LEU A 367
LEU A 460
 None
 1.36A 5veuH-5h2tA:
undetectable		 5veuH-5h2tA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ilb PROTEASE DO-LIKE 2,
CHLOROPLASTIC,PROTEA
SE DO-LIKE 9

(Arabidopsis
thaliana) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 ARG A 171
PHE A 147
LEU A 154
LEU A 115
 None
 1.28A 5veuH-5ilbA:
undetectable		 5veuH-5ilbA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jw6 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Aspergillus
fumigatus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ARG A  70
PHE A  22
LEU A  12
LEU A  64
 None
 1.11A 5veuH-5jw6A:
undetectable		 5veuH-5jw6A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kz5 FRATAXIN,
MITOCHONDRIAL

(Homo sapiens) 		PF01491
(Frataxin_Cyay) 		4 PHE A 127
PHE A 110
LEU A 106
LEU A 136
 None
 1.27A 5veuH-5kz5A:
undetectable		 5veuH-5kz5A:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me5 EIF4G
EUKARYOTIC
TRANSCRIPTION
INITIATION FACTOR 4E

(Cucumis melo) 		PF01652
(IF4E)
no annotation 		4 PHE B1067
PHE A  98
LEU B1064
LEU B1072
 None
 1.10A 5veuH-5me5B:
undetectable		 5veuH-5me5B:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mek CYTOSOLIC
SULFOTRANSFERASE 18

(Arabidopsis
thaliana) 		PF00685
(Sulfotransfer_1) 		4 PHE A 152
PHE A  86
LEU A 151
LEU A 161
 EDO  A 404 (-4.5A)
None
None
None
 1.28A 5veuH-5mekA:
undetectable		 5veuH-5mekA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz6 SEPARASE

(Caenorhabditis
elegans) 		PF03568
(Peptidase_C50) 		4 PHE 1 121
PHE 1  90
LEU 1 118
LEU 1 128
 None
 1.23A 5veuH-5mz61:
undetectable		 5veuH-5mz61:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ool 39S RIBOSOMAL
PROTEIN L37,
MITOCHONDRIAL

(Homo sapiens) 		PF07147
(PDCD9) 		4 PHE 5 318
PHE 5 107
LEU 5 123
LEU 5 355
 None
 1.07A 5veuH-5ool5:
undetectable		 5veuH-5ool5:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tth C-TERMINAL
SPYCATCHER FUSION OF
WILDTYPE ZEBRAFISH
TNF
RECEPTOR-ASSOCIATED
PROTEIN 1

(Danio rerio;
Streptococcus
pyogenes) 		PF00183
(HSP90)
PF13589
(HATPase_c_3) 		4 ARG A 464
PHE A 456
LEU A 482
LEU A 540
 None
 1.21A 5veuH-5tthA:
undetectable		 5veuH-5tthA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1s SEPARIN

(Saccharomyces
cerevisiae) 		PF03568
(Peptidase_C50) 		4 ARG A1606
PHE A1403
LEU A1264
LEU A1394
 None
 1.17A 5veuH-5u1sA:
undetectable		 5veuH-5u1sA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7z ACID CERAMIDASE

(Homo sapiens) 		no annotation 4 ARG B 254
PHE B 204
LEU B 211
LEU A  65
 NAG  B 404 ( 4.8A)
None
None
None
 1.16A 5veuH-5u7zB:
undetectable		 5veuH-5u7zB:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B

(Heterocephalus
glaber) 		no annotation 4 ARG A 254
PHE A 204
LEU A 211
LEU A  65
 NAG  A 408 ( 4.1A)
None
None
None
 1.31A 5veuH-5u81A:
undetectable		 5veuH-5u81A:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9m SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE

(Saccharomyces
cerevisiae) 		PF00080
(Sod_Cu)
PF00403
(HMA) 		4 PHE B 116
PHE B 175
LEU B 115
LEU B 103
 None
 0.87A 5veuH-5u9mB:
undetectable		 5veuH-5u9mB:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vic FAB HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE H  91
PHE H 100
LEU H  45
LEU H  80
 None
 0.99A 5veuH-5vicH:
undetectable		 5veuH-5vicH:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5viy 8ANC195 G52K5 FAB
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PHE K  91
PHE K 100
LEU K  45
LEU K  80
 None
 1.08A 5veuH-5viyK:
undetectable		 5veuH-5viyK:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wu6 SPECKLE TARGETED
PIP5K1A-REGULATED
POLY(A) POLYMERASE

(Homo sapiens) 		PF00076
(RRM_1)
PF03828
(PAP_assoc) 		4 ARG A 477
PHE A 395
LEU A 398
LEU A 390
 None
 1.30A 5veuH-5wu6A:
undetectable		 5veuH-5wu6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xf7 PROTEIN
DISULFIDE-ISOMERASE-
LIKE PROTEIN OF THE
TESTIS

(Homo sapiens) 		no annotation 4 ARG A  61
PHE A 124
PHE A 125
LEU A 148
 None
 1.35A 5veuH-5xf7A:
undetectable		 5veuH-5xf7A:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xh9 EXTRACELLULAR
INVERTASE

(Aspergillus
kawachii) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 PHE A 601
PHE A 600
LEU A 462
LEU A 565
 None
 1.21A 5veuH-5xh9A:
undetectable		 5veuH-5xh9A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnu PUTATIVE INTEGRAL
MEMBRANE PROTEIN

(Escherichia
coli) 		no annotation 4 PHE A 494
PHE A 493
LEU A 270
LEU A 510
 None
 1.21A 5veuH-5xnuA:
undetectable		 5veuH-5xnuA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xsy SODIUM CHANNEL
PROTEIN

(Electrophorus
electricus) 		PF00520
(Ion_trans)
PF06512
(Na_trans_assoc) 		4 PHE A 785
PHE A1254
LEU A 788
LEU A 746
 None
 1.22A 5veuH-5xsyA:
0.6		 5veuH-5xsyA:
13.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9q CARBON CATABOLITE
RESPONSIVE REGULATOR

(Staphylococcus
aureus) 		PF03466
(LysR_substrate) 		4 PHE A 185
PHE A  27
LEU A 188
LEU A 177
 None
 1.26A 5veuH-5y9qA:
undetectable		 5veuH-5y9qA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yrp SENSORY BOX/RESPONSE
REGULATOR

(Mycolicibacterium
smegmatis) 		no annotation 4 ARG A 421
PHE A 427
PHE A 466
LEU A 367
 None
 1.29A 5veuH-5yrpA:
undetectable		 5veuH-5yrpA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yz0 SERINE/THREONINE-PRO
TEIN KINASE ATR

(Homo sapiens) 		no annotation 4 PHE A2138
PHE A2142
LEU A2145
LEU A2169
 None
 1.28A 5veuH-5yz0A:
undetectable		 5veuH-5yz0A:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d14 TNF
RECEPTOR-ASSOCIATED
PROTEIN 1

(Danio rerio) 		no annotation 4 ARG A 464
PHE A 456
LEU A 482
LEU A 540
 None
 1.25A 5veuH-6d14A:
undetectable		 5veuH-6d14A:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d7t TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 6

(Homo sapiens) 		no annotation 4 ARG A 470
PHE A 478
LEU A 475
LEU A 592
 FZ4  A 801 ( 3.7A)
None
None
None
 1.36A 5veuH-6d7tA:
undetectable		 5veuH-6d7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9n CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 1

(Homo sapiens) 		no annotation 4 ARG A 142
PHE A 221
LEU A 220
LEU A 159
 None
 1.25A 5veuH-6f9nA:
undetectable		 5veuH-6f9nA:
9.49