SIMILAR PATTERNS OF AMINO ACIDS FOR 5VCE_A_RITA602_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b48 | PROTEIN (GLUTATHIONES-TRANSFERASE) (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 5 | PHE A 147ILE A 188ILE A 194ALA A 24ALA A 76 | None | 0.96A | 5vceA-1b48A:undetectable | 5vceA-1b48A:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jpu | GLYCEROLDEHYDROGENASE (Geobacillusstearothermophilus) |
PF00465(Fe-ADH) | 5 | ILE A 325ALA A 329THR A 333ILE A 339ALA A 254 | None | 1.00A | 5vceA-1jpuA:undetectable | 5vceA-1jpuA:18.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kyw | CAFFEIC ACID3-O-METHYLTRANSFERASE (Medicago sativa) |
PF00891(Methyltransf_2)PF08100(Dimerisation) | 5 | PHE A 344ILE A 256PHE A 279ALA A 296GLU A 360 | None | 0.96A | 5vceA-1kywA:undetectable | 5vceA-1kywA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8w | VLSE1 (Borreliellaburgdorferi) |
PF00921(Lipoprotein_2) | 5 | PHE A 74ILE A 324ALA A 282ILE A 256GLU A 173 | None | 1.12A | 5vceA-1l8wA:0.0 | 5vceA-1l8wA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qlb | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Wolinellasuccinogenes) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 5 | ILE A 375ALA A 246THR A 243ALA A 183GLU A 180 | None | 1.06A | 5vceA-1qlbA:undetectable | 5vceA-1qlbA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qvb | BETA-GLYCOSIDASE (Thermosphaeraaggregans) |
PF00232(Glyco_hydro_1) | 5 | PHE A 290ILE A 242PHE A 185ALA A 186ILE A 252 | None | 1.03A | 5vceA-1qvbA:0.0 | 5vceA-1qvbA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ued | P450 MONOOXYGENASE (Amycolatopsisorientalis) |
PF00067(p450) | 5 | PHE A 175ILE A 179PHE A 199ALA A 241GLU A 163 | NoneNoneNonePG4 A4502 (-4.3A)None | 1.12A | 5vceA-1uedA:9.7 | 5vceA-1uedA:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5k | MICROTUBULE-ASSOCIATED PROTEIN, RP/EBFAMILY, MEMBER 1 (Mus musculus) |
PF00307(CH) | 5 | PHE A 75ILE A 84PHE A 104ALA A 35ALA A 50 | None | 1.07A | 5vceA-1v5kA:undetectable | 5vceA-1v5kA:11.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa5 | IMPORTIN ALPHARE-EXPORTER (Saccharomycescerevisiae) |
PF03378(CAS_CSE1)PF03810(IBN_N)PF08506(Cse1) | 5 | ILE C 472PHE C 357ALA C 516THR C 519ILE C 482 | None | 1.04A | 5vceA-1wa5C:0.0 | 5vceA-1wa5C:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ydf | HYDROLASE, HALOACIDDEHALOGENASE-LIKEFAMILY (Streptococcuspneumoniae) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 5 | ALA A 172THR A 173ILE A 137ALA A 136GLU A 112 | None | 1.10A | 5vceA-1ydfA:0.0 | 5vceA-1ydfA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z26 | ARGONAUTE (Pyrococcusfuriosus) |
PF02171(Piwi)PF12212(PAZ_siRNAbind) | 5 | PHE A 611ILE A 555PHE A 747ALA A 748ILE A 569 | None | 1.05A | 5vceA-1z26A:undetectable | 5vceA-1z26A:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akj | FERREDOXIN--NITRITEREDUCTASE,CHLOROPLAST (Spinaciaoleracea) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | ILE A 194ILE A 230ALA A 245ALA A 338GLU A 341 | None | 1.01A | 5vceA-2akjA:undetectable | 5vceA-2akjA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akj | FERREDOXIN--NITRITEREDUCTASE,CHLOROPLAST (Spinaciaoleracea) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 5 | PHE A 255ILE A 230ALA A 245ALA A 338GLU A 341 | None | 1.07A | 5vceA-2akjA:undetectable | 5vceA-2akjA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b30 | PVIVAX HYPOTHETICALPROTEIN (Plasmodiumvivax) |
PF08282(Hydrolase_3) | 5 | PHE A 34ILE A 66PHE A 79ALA A 53ALA A 288 | None | 1.11A | 5vceA-2b30A:undetectable | 5vceA-2b30A:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2buc | DIPEPTIDYL PEPTIDASEIV (Sus scrofa) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | ILE A 703ALA A 652THR A 636ILE A 626ALA A 625 | None | 0.92A | 5vceA-2bucA:undetectable | 5vceA-2bucA:21.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dzd | PYRUVATE CARBOXYLASE (Geobacillusthermodenitrificans) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ILE A 297THR A 308ILE A 307ALA A 247GLU A 245 | None | 0.91A | 5vceA-2dzdA:undetectable | 5vceA-2dzdA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fa0 | HMG-COA SYNTHASE (Brassica juncea) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 5 | PHE A 366PHE A 336ALA A 337ILE A 382ALA A 9 | None | 0.96A | 5vceA-2fa0A:undetectable | 5vceA-2fa0A:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g5t | DIPEPTIDYL PEPTIDASE4 (Homo sapiens) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | ILE A 703ALA A 652THR A 636ILE A 626ALA A 625 | None | 0.89A | 5vceA-2g5tA:undetectable | 5vceA-2g5tA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h29 | PROBABLENICOTINATE-NUCLEOTIDEADENYLYLTRANSFERASE (Staphylococcusaureus) |
PF01467(CTP_transf_like) | 5 | PHE A 11ILE A 60ILE A 64ILE A 4GLU A 76 | NoneNoneNoneNoneDND A 998 ( 4.6A) | 1.13A | 5vceA-2h29A:undetectable | 5vceA-2h29A:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j28 | 50S RIBOSOMALPROTEIN L2 (Escherichiacoli) |
PF00181(Ribosomal_L2)PF03947(Ribosomal_L2_C) | 5 | ILE C 90ALA C 105ILE C 115ALA C 75GLU C 99 | NoneNoneNoneNone G B1491 ( 3.5A) | 0.99A | 5vceA-2j28C:undetectable | 5vceA-2j28C:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j6l | ALDEHYDEDEHYDROGENASE FAMILY7 MEMBER A1 (Homo sapiens) |
PF00171(Aldedh) | 5 | PHE A 402ALA A 193THR A 196ILE A 199GLU A 122 | NAI A1501 (-3.9A)NAI A1501 (-4.3A)NoneNoneNone | 1.12A | 5vceA-2j6lA:undetectable | 5vceA-2j6lA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jir | PERIPLASMIC NITRATEREDUCTASE (Desulfovibriodesulfuricans) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 6 | PHE A 228ILE A 289PHE A 296ALA A 297THR A 330ILE A 329 | None | 1.46A | 5vceA-2jirA:undetectable | 5vceA-2jirA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2oae | DIPEPTIDYL PEPTIDASE4 (Rattusnorvegicus) |
PF00326(Peptidase_S9)PF00930(DPPIV_N) | 5 | ILE A 704ALA A 653THR A 637ILE A 627ALA A 626 | None | 0.90A | 5vceA-2oaeA:undetectable | 5vceA-2oaeA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pwz | MALATE DEHYDROGENASE (Escherichiacoli) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | SER A 76ILE A 117ALA A 9THR A 39ALA A 66 | None | 1.13A | 5vceA-2pwzA:undetectable | 5vceA-2pwzA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vqx | METALLOPROTEINASE (Serratiaproteamaculans) |
PF01447(Peptidase_M4)PF02868(Peptidase_M4_C)PF16485(PLN_propep) | 5 | PHE A 311ALA A 312THR A 315ILE A 292ALA A 289 | None | 0.85A | 5vceA-2vqxA:undetectable | 5vceA-2vqxA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ww8 | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcuspneumoniae) |
PF13519(VWA_2) | 5 | ILE A 541ILE A 539ALA A 251THR A 255ILE A 229 | None | 1.10A | 5vceA-2ww8A:undetectable | 5vceA-2ww8A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzf | GLUCOSYLTRANSFERASE (Legionellapneumophila) |
PF16849(Glyco_transf_88) | 5 | ILE A 44ALA A 77ILE A 56ALA A 55GLU A 49 | None | 1.05A | 5vceA-2wzfA:undetectable | 5vceA-2wzfA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzg | GLUCOSYLTRANSFERASE (Legionellapneumophila) |
PF16849(Glyco_transf_88) | 5 | ILE A 44ALA A 77ILE A 56ALA A 55GLU A 49 | None | 0.92A | 5vceA-2wzgA:undetectable | 5vceA-2wzgA:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ych | COMPETENCE PROTEINPILM (Thermusthermophilus) |
PF11104(PilM_2) | 5 | ILE A 65ILE A 20ALA A 82ALA A 369GLU A 29 | None | 1.13A | 5vceA-2ychA:undetectable | 5vceA-2ychA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zle | PROTEASE DO (Escherichiacoli) |
PF00595(PDZ)PF13365(Trypsin_2) | 5 | ILE A 104ILE A 102ALA A 100ILE A 179ALA A 168 | None | 1.13A | 5vceA-2zleA:undetectable | 5vceA-2zleA:21.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayn | RHODOPSIN (Todarodespacificus) |
PF00001(7tm_1) | 5 | SER A 263ILE A 266ILE A 129ALA A 69THR A 67 | None | 1.04A | 5vceA-3aynA:undetectable | 5vceA-3aynA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cl6 | PUUE ALLANTOINASE (Pseudomonasfluorescens) |
PF01522(Polysacc_deac_1) | 5 | ILE A 276PHE A 275ALA A 279ILE A 27ALA A 28 | None | 1.01A | 5vceA-3cl6A:undetectable | 5vceA-3cl6A:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dzb | PREPHENATEDEHYDROGENASE (Streptococcusthermophilus) |
PF02153(PDH) | 5 | ILE A 22ILE A 68ALA A 97ALA A 126GLU A 142 | None | 1.02A | 5vceA-3dzbA:undetectable | 5vceA-3dzbA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e5d | PUTATIVE GLYOXALASEI (Listeriamonocytogenes) |
PF00903(Glyoxalase) | 5 | ILE A 74ILE A 76THR A 88ILE A 98ALA A 99 | None | 1.09A | 5vceA-3e5dA:undetectable | 5vceA-3e5dA:11.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f6g | ALPHA-ISOPROPYLMALATE SYNTHASE (Leptospirainterrogans) |
no annotation | 6 | ILE B 448ALA B 499THR B 496ILE B 399ALA B 409GLU B 422 | None | 1.47A | 5vceA-3f6gB:undetectable | 5vceA-3f6gB:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g10 | CCR4-NOT COMPLEXSUBUNIT CAF1 (Schizosaccharomycespombe) |
PF04857(CAF1) | 5 | PHE A 109ILE A 84ALA A 241THR A 104ILE A 22 | None | 1.11A | 5vceA-3g10A:undetectable | 5vceA-3g10A:21.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g40 | NA-K-CLCOTRANSPORTER (Methanosarcinaacetivorans) |
no annotation | 5 | ILE A 631ILE A 722ALA A 748ILE A 585ALA A 494 | None | 1.13A | 5vceA-3g40A:undetectable | 5vceA-3g40A:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g85 | TRANSCRIPTIONALREGULATOR (LACIFAMILY) (Clostridiumacetobutylicum) |
PF13377(Peripla_BP_3) | 5 | ILE A 307ILE A 127PHE A 151ALA A 129ILE A 80 | None | 1.09A | 5vceA-3g85A:undetectable | 5vceA-3g85A:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g8d | BIOTIN CARBOXYLASE (Escherichiacoli) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ILE A 293THR A 304ILE A 303ALA A 243GLU A 241 | None | 0.95A | 5vceA-3g8dA:undetectable | 5vceA-3g8dA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvn | HEMOLYSIN (Streptococcussuis) |
PF01289(Thiol_cytolysin)PF17440(Thiol_cytolys_C) | 5 | PHE A 37ILE A 256PHE A 242ILE A 117ALA A 370 | None | 0.84A | 5vceA-3hvnA:undetectable | 5vceA-3hvnA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3li9 | HYPOTHETICAL SENSORYTRANSDUCTIONHISTIDINE KINASE (Methanosarcinamazei) |
PF02743(dCache_1) | 5 | SER A 291ILE A 259ALA A 51ILE A 212ALA A 209 | None | 1.02A | 5vceA-3li9A:undetectable | 5vceA-3li9A:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lk6 | LIPOPROTEIN YBBD (Bacillussubtilis) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C) | 5 | PHE A 604ILE A 472ILE A 457ALA A 459GLU A 432 | None | 1.03A | 5vceA-3lk6A:undetectable | 5vceA-3lk6A:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ne2 | PROBABLE AQUAPORINAQPM (Archaeoglobusfulgidus) |
PF00230(MIP) | 5 | PHE A 109ILE A 105ILE A 88ALA A 233THR A 155 | None | 1.08A | 5vceA-3ne2A:undetectable | 5vceA-3ne2A:20.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qgk | UREASE SUBUNIT BETA2 (Helicobactermustelae) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 5 | ILE C 401PHE C 441ILE C 405ALA C 129ILE C 85 | None | 1.11A | 5vceA-3qgkC:undetectable | 5vceA-3qgkC:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3h | O-METHYLTRANSFERASE,SAM-DEPENDENT (Legionellapneumophila) |
PF01596(Methyltransf_3) | 5 | PHE A 137ILE A 89ALA A 144ILE A 168ALA A 167 | None | 1.07A | 5vceA-3r3hA:undetectable | 5vceA-3r3hA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rko | NADH-QUINONEOXIDOREDUCTASESUBUNIT JNADH-QUINONEOXIDOREDUCTASESUBUNIT K (Escherichiacoli) |
no annotation | 5 | SER J 40ILE J 56ALA J 12THR J 16ILE K 37 | None | 1.01A | 5vceA-3rkoJ:undetectable | 5vceA-3rkoJ:16.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t32 | AMINOTRANSFERASE,CLASS I/II (Bacillusanthracis) |
PF00155(Aminotran_1_2) | 5 | ILE A 85ALA A 94THR A 97ALA A 252GLU A 247 | None | 1.10A | 5vceA-3t32A:undetectable | 5vceA-3t32A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7c | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 5 | ILE A 143ILE A 152ALA A 102THR A 13ILE A 37 | None | 0.93A | 5vceA-3t7cA:undetectable | 5vceA-3t7cA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tbf | GLUCOSAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] (Francisellatularensis) |
PF01380(SIS) | 5 | ILE A 481PHE A 407ALA A 415THR A 418ILE A 316 | None | 1.09A | 5vceA-3tbfA:undetectable | 5vceA-3tbfA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tqp | ENOLASE (Coxiellaburnetii) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 363ALA A 422ILE A 282ALA A 242GLU A 166 | NoneNoneNoneNone MG A 430 ( 4.7A) | 1.11A | 5vceA-3tqpA:2.1 | 5vceA-3tqpA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vom | PUTATIVEPHOSPHOSERINEAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00266(Aminotran_5) | 5 | PHE A 22ALA A 292THR A 298ALA A 323GLU A 339 | None | 1.12A | 5vceA-3vomA:undetectable | 5vceA-3vomA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vvl | HOMOSERINEO-ACETYLTRANSFERASE (Streptomyceslavendulae) |
PF00561(Abhydrolase_1) | 5 | PHE A 118ILE A 126ALA A 130THR A 133GLU A 3 | None | 1.04A | 5vceA-3vvlA:undetectable | 5vceA-3vvlA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wel | ALPHA-GLUCOSIDASE (Beta vulgaris) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF16863(NtCtMGAM_N) | 5 | PHE A 619ILE A 750PHE A 727ALA A 644ILE A 349 | None | 0.94A | 5vceA-3welA:undetectable | 5vceA-3welA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zuk | ENDOPEPTIDASE,PEPTIDASE FAMILY M13 (Mycobacteriumtuberculosis) |
PF01431(Peptidase_M13)PF05649(Peptidase_M13_N) | 5 | ILE A 357ILE A 487ALA A 489ILE A 570ALA A 367 | None | 1.08A | 5vceA-3zukA:undetectable | 5vceA-3zukA:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dna | PROBABLE GLUTATHIONEREDUCTASE (Sinorhizobiummeliloti) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 11PHE A 324ALA A 321ALA A 25GLU A 109 | FAD A 500 (-4.8A)NoneNoneNoneNone | 1.12A | 5vceA-4dnaA:undetectable | 5vceA-4dnaA:22.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 5 | PHE A 191ILE A 189PHE A 203ALA A 158GLU A 171 | None | 1.06A | 5vceA-4fdwA:undetectable | 5vceA-4fdwA:22.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fgs | PROBABLEDEHYDROGENASEPROTEIN (Rhizobium etli) |
PF13561(adh_short_C2) | 5 | ILE A 176ILE A 174ALA A 128ILE A 9ALA A 10 | None | 1.11A | 5vceA-4fgsA:undetectable | 5vceA-4fgsA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h7n | ALDEHYDEDEHYDROGENASE (Trichormusvariabilis) |
PF00171(Aldedh) | 5 | PHE A 279ILE A 269ILE A 266ILE A 415ALA A 401 | None | 1.13A | 5vceA-4h7nA:undetectable | 5vceA-4h7nA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkt | INOSITOL2-DEHYDROGENASE (Sinorhizobiummeliloti) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | PHE A 5PHE A 290ILE A 89THR A 70ALA A 33 | None | 1.06A | 5vceA-4hktA:undetectable | 5vceA-4hktA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwv | PECTATE LYASE/AMBALLERGEN (Acidovoraxcitrulli) |
PF00544(Pec_lyase_C) | 5 | SER A 436ILE A 417ALA A 419ALA A 426GLU A 433 | None | 1.03A | 5vceA-4hwvA:undetectable | 5vceA-4hwvA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i8v | CYTOCHROME P450 1A1 (Homo sapiens) |
PF00067(p450) | 5 | PHE A 123SER A 116ILE A 115PHE A 224ALA A 138 | NoneBHF A 602 (-3.2A)BHF A 602 (-4.7A)BHF A 602 (-3.3A)None | 1.13A | 5vceA-4i8vA:31.3 | 5vceA-4i8vA:26.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ij4 | CHITINASE A (Gemmabryumcoronatum) |
PF00182(Glyco_hydro_19) | 5 | PHE A 12ILE A 58ALA A 136THR A 135ALA A 126 | None | 1.10A | 5vceA-4ij4A:0.4 | 5vceA-4ij4A:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lgn | CELLULOSE-BINDING,FAMILY II (Acidothermuscellulolyticus) |
no annotation | 5 | ILE A 341ILE A 421ALA A 406ILE A 23ALA A 385 | NoneNoneACT A 826 (-4.3A)NoneNone | 1.06A | 5vceA-4lgnA:undetectable | 5vceA-4lgnA:20.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mr0 | PLASMIN ANDFIBRONECTIN-BINDINGPROTEIN A (Streptococcuspneumoniae) |
PF12708(Pectate_lyase_3)PF13229(Beta_helix) | 5 | ILE A 171PHE A 189ILE A 175ILE A 284ALA A 283 | None | 1.01A | 5vceA-4mr0A:undetectable | 5vceA-4mr0A:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mv3 | BIOTIN CARBOXYLASE (Haemophilusinfluenzae) |
PF00289(Biotin_carb_N)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 5 | ILE A 293THR A 304ILE A 303ALA A 243GLU A 241 | None | 0.95A | 5vceA-4mv3A:undetectable | 5vceA-4mv3A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n91 | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT (Anaerococcusprevotii) |
PF03480(DctP) | 5 | PHE A 115ILE A 328PHE A 109ILE A 130GLU A 119 | None | 1.11A | 5vceA-4n91A:0.0 | 5vceA-4n91A:20.83 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ny4 | CYTOCHROME P450 3A4 (Homo sapiens) |
PF00067(p450) | 10 | PHE A 108SER A 119ILE A 120PHE A 241ILE A 301ALA A 305THR A 309ILE A 369ALA A 370GLU A 374 | 2QH A 602 (-4.4A)2QH A 602 (-3.9A)None2QH A 602 (-4.5A)None2QH A 602 ( 3.6A)2QH A 602 ( 3.7A)HEM A 601 (-4.7A)2QH A 602 ( 3.1A)2QH A 602 ( 4.8A) | 0.61A | 5vceA-4ny4A:57.8 | 5vceA-4ny4A:98.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ny4 | CYTOCHROME P450 3A4 (Homo sapiens) |
PF00067(p450) | 7 | SER A 119ILE A 120ARG A 212PHE A 241ILE A 301THR A 309ILE A 369 | 2QH A 602 (-3.9A)None2QH A 602 (-4.0A)2QH A 602 (-4.5A)None2QH A 602 ( 3.7A)HEM A 601 (-4.7A) | 1.24A | 5vceA-4ny4A:57.8 | 5vceA-4ny4A:98.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ov4 | 2-ISOPROPYLMALATESYNTHASE (Leptospirabiflexa) |
PF00682(HMGL-like) | 5 | ILE A 100ILE A 124ALA A 161ILE A 194GLU A 231 | None | 1.13A | 5vceA-4ov4A:undetectable | 5vceA-4ov4A:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4po5 | ALLOPHYCOCYANINSUBUNIT ALPHA-B (Synechocystissp. PCC 6803) |
PF00502(Phycobilisome) | 5 | ILE A 156PHE A 153THR A 149ILE A 39ALA A 40 | None | 1.08A | 5vceA-4po5A:2.3 | 5vceA-4po5A:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv4 | PROLINEAMINOPEPTIDASE P II (Yersinia pestis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 5 | ILE A 111PHE A 26ILE A 61ALA A 22ALA A 156 | NoneNoneNoneNoneEDO A 505 ( 4.9A) | 0.99A | 5vceA-4pv4A:undetectable | 5vceA-4pv4A:22.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxn | UNCHARACTERIZEDPROTEIN (Zea mays) |
PF00171(Aldedh) | 5 | PHE A 399ALA A 191THR A 194ILE A 197GLU A 120 | NAD A 601 (-3.9A)NAD A 601 (-4.2A)NoneNoneNone | 1.07A | 5vceA-4pxnA:undetectable | 5vceA-4pxnA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q3k | MGS-M1 (unidentified) |
PF00326(Peptidase_S9)PF07859(Abhydrolase_3) | 5 | ILE A 110ALA A 123THR A 158ILE A 189GLU A 192 | None | 1.07A | 5vceA-4q3kA:undetectable | 5vceA-4q3kA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tjv | VACUOLAR-SORTINGRECEPTOR 1 (Arabidopsisthaliana) |
PF02225(PA) | 5 | ILE A 159ILE A 151ALA A 149ILE A 146ALA A 113 | None | 0.99A | 5vceA-4tjvA:undetectable | 5vceA-4tjvA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tr6 | DNA POLYMERASE IIISUBUNIT BETA (Bacillussubtilis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | ILE A 304PHE A 273ILE A 302THR A 264ALA A 356 | None | 1.10A | 5vceA-4tr6A:undetectable | 5vceA-4tr6A:23.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzo | PUTATIVE ACYL-COAACYLTRANSFERASE (Sulfurisphaeratokodaii) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 5 | ILE A 83ILE A 227ALA A 255ILE A 264ALA A 267 | None | 1.08A | 5vceA-4yzoA:0.2 | 5vceA-4yzoA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5s | ALDEHYDEDECARBONYLASE (Synechocystissp. PCC 6803) |
PF11266(Ald_deCOase) | 5 | ILE A 109PHE A 117ALA A 118ILE A 27ALA A 83 | None | 1.09A | 5vceA-4z5sA:undetectable | 5vceA-4z5sA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b7s | CYSTEINE DESULFURASE (Thermococcusonnurineus) |
PF00266(Aminotran_5) | 5 | PHE A 82ILE A 80ILE A 73ALA A 195GLU A 88 | None | 1.03A | 5vceA-5b7sA:undetectable | 5vceA-5b7sA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ep5 | THIOESTERASE (Staphylococcusaureus) |
PF03061(4HBT) | 5 | ILE A 90ALA A 72THR A 112ILE A 103ALA A 85 | None | 1.08A | 5vceA-5ep5A:undetectable | 5vceA-5ep5A:12.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h0k | UNCHARACTERIZEDPROTEIN (Pedobacterheparinus) |
PF16265(DUF4918) | 5 | ILE A 103PHE A 116ILE A 122ILE A 200ALA A 202 | None | 1.07A | 5vceA-5h0kA:undetectable | 5vceA-5h0kA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h0k | UNCHARACTERIZEDPROTEIN (Pedobacterheparinus) |
PF16265(DUF4918) | 5 | ILE A 103PHE A 116ILE A 122ILE A 200GLU A 204 | None | 0.94A | 5vceA-5h0kA:undetectable | 5vceA-5h0kA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1z | PUTATIVE CYP ALKANEHYDROXYLASECYP153D17 (Sphingomonassp. PAMC 26605) |
PF00067(p450) | 5 | ILE A 79ALA A 76THR A 74ILE A 73ALA A 93 | NoneNoneD12 A 502 (-3.5A)NoneNone | 0.97A | 5vceA-5h1zA:28.0 | 5vceA-5h1zA:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3k | SLR0280 PROTEIN (Synechocystissp. PCC 6803) |
no annotation | 5 | ILE A 542ILE A 534ALA A 340ILE A 328ALA A 329 | None | 1.10A | 5vceA-5h3kA:undetectable | 5vceA-5h3kA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h8y | SULFITE REDUCTASE[FERREDOXIN],CHLOROPLASTIC (Zea mays) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 6 | SER A 302PHE A 209ALA A 210THR A 213ILE A 344GLU A 394 | None | 1.49A | 5vceA-5h8yA:undetectable | 5vceA-5h8yA:23.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k52 | ALDEHYDEDECARBONYLASE (Limnothrix sp.KNUA012) |
PF11266(Ald_deCOase) | 5 | ILE A 109PHE A 117ALA A 118ILE A 27ALA A 83 | NoneOCD A 500 (-3.9A)OCD A 500 (-3.6A)OCD A 500 ( 4.6A)None | 1.12A | 5vceA-5k52A:undetectable | 5vceA-5k52A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kf2 | PREDICTEDACETYLTRANSFERASE (Clostridiumacetobutylicum) |
PF00583(Acetyltransf_1) | 5 | PHE A 136ILE A 78ALA A 100ILE A 3ALA A 47 | None | 1.13A | 5vceA-5kf2A:undetectable | 5vceA-5kf2A:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5p | PRE-MRNA-SPLICINGHELICASE BRR2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 5 | ILE A1472ILE A1398PHE A1452ILE A1498ALA A1499 | None | 1.03A | 5vceA-5m5pA:undetectable | 5vceA-5m5pA:13.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mdh | MALATE DEHYDROGENASE (Sus scrofa) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 5 | PHE A 29ILE A 35ALA A 11ILE A 15ALA A 246 | NoneNoneNoneNAD A 334 (-3.4A)None | 1.11A | 5vceA-5mdhA:undetectable | 5vceA-5mdhA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz9 | - (-) |
no annotation | 5 | SER A 50ILE A 122THR A 777ILE A 790ALA A 44 | PO4 A1002 (-4.4A)NoneNoneNoneNone | 1.12A | 5vceA-5mz9A:undetectable | 5vceA-5mz9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uv2 | (+)-LIMONENESYNTHASE (Citrus sinensis) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | SER A 454ILE A 453ILE A 319ILE A 476GLU A 471 | None | 1.05A | 5vceA-5uv2A:undetectable | 5vceA-5uv2A:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ve8 | KAP123 (Kluyveromyceslactis) |
no annotation | 5 | ILE A 557PHE A 569ALA A 600ILE A 617GLU A 582 | None | 0.95A | 5vceA-5ve8A:undetectable | 5vceA-5ve8A:18.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5veu | CYTOCHROME P450 3A5 (Homo sapiens) |
no annotation | 7 | SER A 119PHE A 241ILE A 301PHE A 304ALA A 305THR A 309ALA A 370 | RIT A 602 (-3.7A)RIT A 602 (-3.9A)RIT A 602 ( 4.9A)RIT A 602 (-3.7A)HEM A 601 (-3.4A)HEM A 601 ( 3.5A)RIT A 602 (-3.3A) | 0.74A | 5vceA-5veuA:53.9 | 5vceA-5veuA:82.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdu | ENVELOPEGLYCOPROTEIN GP160 (Humanimmunodeficiencyvirus 1) |
no annotation | 5 | PHE G 176PHE G 159ILE G 307ALA G 316ALA G 204 | None | 1.07A | 5vceA-5wduG:undetectable | 5vceA-5wduG:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xn8 | GLYCEROLDEHYDROGENASE (unidentified) |
PF00465(Fe-ADH) | 5 | SER A 288ILE A 293ALA A 355ILE A 256ALA A 252 | None | 1.05A | 5vceA-5xn8A:undetectable | 5vceA-5xn8A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y31 | LEUCINE-RICHGLIOMA-INACTIVATEDPROTEIN 1 (Homo sapiens) |
no annotation | 5 | PHE B 272SER B 229ILE B 547ARG B 533GLU B 269 | None | 1.12A | 5vceA-5y31B:undetectable | 5vceA-5y31B:9.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y33 | ALGINATE LYASE (Flavobacteriumsp. UMI-01) |
no annotation | 5 | ILE A 104ILE A 120ALA A 236ILE A 6ALA A 4 | None | 1.07A | 5vceA-5y33A:undetectable | 5vceA-5y33A:10.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6q | ALDEHYDE OXIDASEMEDIUM SUBUNIT (Methylobacillussp. KY4400) |
no annotation | 5 | PHE B 195ILE B 191ILE B 217ALA B 70ILE B 213 | NoneNoneNoneFAD B 401 ( 4.0A)FAD B 401 (-3.5A) | 1.08A | 5vceA-5y6qB:undetectable | 5vceA-5y6qB:9.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MEMBRANE-BOUNDHYDROGENASE SUBUNITALPHAPROBABLEMEMBRANE-BOUNDHYDROGENASE SUBUNITMBHJ (Pyrococcusfuriosus) |
no annotation | 5 | ILE L 70ILE J 40ALA J 44THR J 47ALA L 134 | NFU L 401 ( 4.8A)NoneNoneNoneNone | 0.95A | 5vceA-6cfwL:undetectable | 5vceA-6cfwL:10.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cfw | MONOVALENT CATION/H+ANTIPORTER SUBUNIT BMONOVALENT CATION/H+ANTIPORTER SUBUNIT EMONOVALENT CATION/H+ANTIPORTER SUBUNIT F (Pyrococcusfuriosus) |
no annotation | 5 | PHE F 23ILE B 62ILE B 58ALA B 55ALA A 19 | None | 1.07A | 5vceA-6cfwF:undetectable | 5vceA-6cfwF:11.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6erc | PEROXINECTIN A (Dictyosteliumdiscoideum) |
no annotation | 5 | PHE A 92PHE A 323ILE A 478ILE A 170GLU A 289 | NoneHEM A 604 ( 3.9A)NoneNoneNone | 1.05A | 5vceA-6ercA:undetectable | 5vceA-6ercA:10.53 |