SIMILAR PATTERNS OF AMINO ACIDS FOR 5V0V_A_8QPA612_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a3x | PYRUVATE KINASE (Saccharomycescerevisiae) |
PF00224(PK)PF02887(PK_C) | 5 | LYS A 1LEU A 10LEU A 323ILE A 359ALA A 360 | None | 1.10A | 5v0vA-1a3xA:undetectable | 5v0vA-1a3xA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a8p | NADPH:FERREDOXINOXIDOREDUCTASE (Azotobactervinelandii) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | GLU A 88LEU A 83LEU A 80ILE A 40GLU A 7 | None | 1.12A | 5v0vA-1a8pA:undetectable | 5v0vA-1a8pA:17.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cvr | GINGIPAIN R (Porphyromonasgingivalis) |
PF01364(Peptidase_C25)PF03785(Peptidase_C25_C) | 5 | GLU A 21LEU A 75ILE A 46ALA A 43GLU A 44 | None | 1.19A | 5v0vA-1cvrA:undetectable | 5v0vA-1cvrA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dvk | PRP18 (Saccharomycescerevisiae) |
PF02840(Prp18) | 5 | LEU A 147LEU A 121ARG A 235LEU A 236ALA A 142 | None | 1.21A | 5v0vA-1dvkA:undetectable | 5v0vA-1dvkA:14.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ipi | HOLLIDAY JUNCTIONRESOLVASE (Pyrococcusfuriosus) |
PF01870(Hjc) | 5 | GLU A 9LEU A 109LEU A 16LEU A 43ALA A 79 | None | 1.08A | 5v0vA-1ipiA:undetectable | 5v0vA-1ipiA:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mlz | 7,8-DIAMINO-PELARGONIC ACIDAMINOTRANSFERASE (Escherichiacoli) |
PF00202(Aminotran_3) | 5 | GLU A 90LEU A 64ILE A 326ALA A 325GLU A 328 | None | 1.20A | 5v0vA-1mlzA:undetectable | 5v0vA-1mlzA:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qfu | PROTEIN(IMMUNOGLOBULINIGG1-KAPPA ANTIBODY(HEAVY CHAIN)) (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 5 | LYS H 62LEU H 82LEU H 82LEU H 20GLU H 46 | None | 1.17A | 5v0vA-1qfuH:undetectable | 5v0vA-1qfuH:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qok | MFE-23 RECOMBINANTANTIBODY FRAGMENT (Mus musculus) |
PF07686(V-set) | 5 | LYS A 89LEU A 112LEU A 109LEU A 46GLU A 72 | None | 1.16A | 5v0vA-1qokA:undetectable | 5v0vA-1qokA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r5p | CIRCADIANOSCILLATIONREGULATOR (Nostoc sp. PCC7120) |
PF07689(KaiB) | 5 | GLU A 33LEU A 69LEU A 10LEU A 12ILE A 76 | None | 1.19A | 5v0vA-1r5pA:undetectable | 5v0vA-1r5pA:12.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t6k | PHENAZINEBIOSYNTHESIS PROTEINPHZF (Pseudomonasfluorescens) |
PF02567(PhzC-PhzF) | 5 | LEU A 94LEU A 92LEU A 105ILE A 81ALA A 82 | None | 1.15A | 5v0vA-1t6kA:0.0 | 5v0vA-1t6kA:19.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t90 | PROBABLEMETHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Bacillussubtilis) |
PF00171(Aldedh) | 5 | LEU A 260LEU A 414ILE A 400ALA A 399GLU A 398 | None | 1.12A | 5v0vA-1t90A:undetectable | 5v0vA-1t90A:21.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | ARG A 257LEU A 260ILE A 290ALA A 291GLU A 292 | DKA A1003 (-4.1A)NoneDKA A1003 ( 4.5A)CIT A2001 ( 3.9A)None | 1.08A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | HIS A 242LEU A 260ILE A 290ALA A 291GLU A 292 | DKA A1003 (-3.7A)NoneDKA A1003 ( 4.5A)CIT A2001 ( 3.9A)None | 0.96A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | LEU A 219LEU A 238ARG A 257LEU A 260ILE A 290ALA A 291 | NoneDKA A1003 (-4.3A)DKA A1003 (-4.1A)NoneDKA A1003 ( 4.5A)CIT A2001 ( 3.9A) | 0.57A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 6 | LEU A 219LEU A 238HIS A 242LEU A 260ILE A 290ALA A 291 | NoneDKA A1003 (-4.3A)DKA A1003 (-3.7A)NoneDKA A1003 ( 4.5A)CIT A2001 ( 3.9A) | 0.60A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LYS A 195LEU A 219LEU A 238ARG A 257LEU A 260 | CIT A2001 (-4.1A)NoneDKA A1003 (-4.3A)DKA A1003 (-4.1A)None | 0.90A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LYS A 195LEU A 219LEU A 238HIS A 242LEU A 260 | CIT A2001 (-4.1A)NoneDKA A1003 (-4.3A)DKA A1003 (-3.7A)None | 1.03A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tf0 | SERUM ALBUMIN (Homo sapiens) |
PF00273(Serum_albumin) | 5 | LYS A 199LEU A 219LEU A 238HIS A 242LEU A 260 | CIT A2001 ( 2.7A)NoneDKA A1003 (-4.3A)DKA A1003 (-3.7A)None | 1.10A | 5v0vA-1tf0A:46.0 | 5v0vA-1tf0A:76.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vq0 | 33 KDA CHAPERONIN (Thermotogamaritima) |
PF01430(HSP33) | 5 | LEU A 35LEU A 94ILE A 108ALA A 105GLU A 135 | None | 1.21A | 5v0vA-1vq0A:undetectable | 5v0vA-1vq0A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xtp | LMAJ004091AAA (Leishmaniamajor) |
PF05891(Methyltransf_PK) | 5 | TYR A 50GLU A 150LEU A 224LEU A 214ALA A 168 | NoneSAI A 401 (-3.3A)NoneNoneNone | 1.14A | 5v0vA-1xtpA:undetectable | 5v0vA-1xtpA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzw | PURPLE ACIDPHOSPHATASE (Ipomoea batatas) |
PF00149(Metallophos)PF14008(Metallophos_C)PF16656(Pur_ac_phosph_N) | 5 | TYR A 127LEU A 283LEU A 159LEU A 131ILE A 317 | None | 1.08A | 5v0vA-1xzwA:undetectable | 5v0vA-1xzwA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ycq | MDM2 (Xenopus laevis) |
PF02201(SWIB) | 5 | LYS A 41LEU A 103LEU A 30ILE A 50GLU A 48 | None | 1.00A | 5v0vA-1ycqA:undetectable | 5v0vA-1ycqA:11.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yrg | GTPASE-ACTIVATINGPROTEIN RNA1_SCHPO (Schizosaccharomycespombe) |
no annotation | 5 | HIS A 186LEU A 127ILE A 142ALA A 143GLU A 178 | None | 1.03A | 5v0vA-1yrgA:undetectable | 5v0vA-1yrgA:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zzp | PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1 (Homo sapiens) |
PF08919(F_actin_bind) | 5 | GLU A 65LEU A 97LEU A 101LEU A 104ILE A 50 | None | 1.21A | 5v0vA-1zzpA:3.2 | 5v0vA-1zzpA:11.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a9j | BISPHOSPHOGLYCERATEMUTASE (Homo sapiens) |
PF00300(His_Phos_1) | 5 | LEU A 222LEU A 199LEU A 195ILE A 173ALA A 174 | None | 1.15A | 5v0vA-2a9jA:undetectable | 5v0vA-2a9jA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bcc | UBIQUINOL CYTOCHROMEC OXIDOREDUCTASE (Gallus gallus) |
PF00675(Peptidase_M16)PF05193(Peptidase_M16_C) | 5 | GLU A 130LEU A 186LEU A 122ILE A 116ALA A 63 | None | 1.18A | 5v0vA-2bccA:undetectable | 5v0vA-2bccA:23.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2chq | REPLICATION FACTOR CSMALL SUBUNIT (Archaeoglobusfulgidus) |
PF00004(AAA)PF08542(Rep_fac_C) | 5 | GLU A 245LEU A 310LEU A 313ILE A 235GLU A 233 | None | 1.22A | 5v0vA-2chqA:3.3 | 5v0vA-2chqA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ljw | ALR2454 PROTEIN (Nostoc sp. PCC7120) |
PF11267(DUF3067) | 5 | LYS A 85LEU A 31LEU A 10ILE A 74GLU A 79 | None | 1.12A | 5v0vA-2ljwA:undetectable | 5v0vA-2ljwA:10.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2mb9 | B-CELLLYMPHOMA/LEUKEMIA 10 (Homo sapiens) |
PF00619(CARD) | 5 | LEU A 72LEU A 82LEU A 41ILE A 55ALA A 65 | None | 1.16A | 5v0vA-2mb9A:undetectable | 5v0vA-2mb9A:12.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2py8 | HYPOTHETICAL PROTEINRBCX (Synechocystissp. PCC 6803) |
PF02341(RcbX) | 5 | LEU A 86LEU A 14ILE A 78ALA A 79GLU A 80 | None | 0.86A | 5v0vA-2py8A:undetectable | 5v0vA-2py8A:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdx | FERREDOXIN REDUCTASE (Pseudomonasaeruginosa) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 5 | GLU A 88LEU A 83LEU A 80ILE A 40GLU A 7 | None | 1.08A | 5v0vA-2qdxA:undetectable | 5v0vA-2qdxA:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qzq | AXIN INTERACTOR,DORSALIZATIONASSOCIATED PROTEIN (Danio rerio) |
PF14186(Aida_C2) | 5 | LEU A 98LEU A 66ILE A 104ALA A 103GLU A 127 | None | 1.13A | 5v0vA-2qzqA:undetectable | 5v0vA-2qzqA:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rgj | FLAVIN-CONTAININGMONOOXYGENASE (Pseudomonasaeruginosa) |
PF01494(FAD_binding_3) | 5 | GLU A 59LEU A 113LEU A 62LEU A 66ILE A 49 | None | 1.20A | 5v0vA-2rgjA:undetectable | 5v0vA-2rgjA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2whn | PILUS ASSEMBLYPROTEIN PILC (Thermusthermophilus) |
PF00482(T2SSF) | 5 | GLU A 112LEU A 74ILE A 90ALA A 89GLU A 92 | None | 1.12A | 5v0vA-2whnA:undetectable | 5v0vA-2whnA:13.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvp | MUTT/NUDIX FAMILYPROTEIN (Thermusthermophilus) |
PF00293(NUDIX) | 5 | LEU A 146ARG A 59LEU A 57ILE A 160GLU A 159 | None | 1.15A | 5v0vA-2yvpA:undetectable | 5v0vA-2yvpA:16.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ywb | GMP SYNTHASE[GLUTAMINE-HYDROLYZING] (Thermusthermophilus) |
PF00117(GATase)PF00958(GMP_synt_C) | 5 | GLU A 37LEU A 356LEU A 27HIS A 41ILE A 322 | None | 1.20A | 5v0vA-2ywbA:undetectable | 5v0vA-2ywbA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bxj | RASGTPASE-ACTIVATINGPROTEIN SYNGAP (Rattusnorvegicus) |
PF00168(C2)PF00616(RasGAP) | 5 | GLU A 431LEU A 416LEU A 681ILE A 439ALA A 435 | None | 1.21A | 5v0vA-3bxjA:2.0 | 5v0vA-3bxjA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dra | GERANYLGERANYLTRANSFERASE TYPE I BETASUBUNIT (Candidaalbicans) |
PF00432(Prenyltrans) | 5 | LEU B 367LEU B 4HIS B 9LEU B 326ALA B 353 | None | 1.13A | 5v0vA-3draB:undetectable | 5v0vA-3draB:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kfu | NON-DISCRIMINATINGAND ARCHAEAL-TYPEASPARTYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | LYS A 183GLU A 220LEU A 139LEU A 237ILE A 392 | None | 0.84A | 5v0vA-3kfuA:undetectable | 5v0vA-3kfuA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kfu | NON-DISCRIMINATINGAND ARCHAEAL-TYPEASPARTYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 5 | LYS A 183GLU A 220LEU A 237ILE A 392ALA A 391 | None | 1.20A | 5v0vA-3kfuA:undetectable | 5v0vA-3kfuA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lnt | 2,3-BISPHOSPHOGLYCERATE-DEPENDENTPHOSPHOGLYCERATEMUTASE (Burkholderiapseudomallei) |
PF00300(His_Phos_1) | 5 | LEU A 216LEU A 193LEU A 189ILE A 167ALA A 168 | None | 1.15A | 5v0vA-3lntA:undetectable | 5v0vA-3lntA:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mem | PUTATIVE SIGNALTRANSDUCTION PROTEIN (Marinobacterhydrocarbonoclasticus) |
PF04073(tRNA_edit)PF08668(HDOD) | 5 | TYR A 278LEU A 183LEU A 265ILE A 359ALA A 360 | None | 1.21A | 5v0vA-3memA:undetectable | 5v0vA-3memA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkb | HEMOGLOBIN SUBUNITALPHA (Isurusoxyrinchus) |
PF00042(Globin) | 5 | LEU A 128LEU A 106LEU A 109ALA A 123GLU A 6 | None | 1.08A | 5v0vA-3mkbA:2.5 | 5v0vA-3mkbA:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mzv | DECAPRENYLDIPHOSPHATE SYNTHASE (Rhodobactercapsulatus) |
PF00348(polyprenyl_synt) | 5 | LEU A 18LEU A 317HIS A 315LEU A 321ALA A 65 | None | 1.19A | 5v0vA-3mzvA:undetectable | 5v0vA-3mzvA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tw5 | TRANSGLUTAMINASEELICITOR (Phytophthorasojae) |
PF16683(TGase_elicitor) | 5 | TYR A 468LEU A 185HIS A 368LEU A 472GLU A 404 | NoneNoneNoneNoneCXS A 1 (-2.8A) | 1.15A | 5v0vA-3tw5A:undetectable | 5v0vA-3tw5A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1l | CRISPR SYSTEM CMRSUBUNIT CMR5 (Archaeoglobusfulgidus) |
PF09701(Cas_Cmr5) | 5 | TYR F 35LYS F 144LEU F 94ILE F 45ALA F 42 | None | 1.18A | 5v0vA-3x1lF:undetectable | 5v0vA-3x1lF:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af1 | PEPTIDE CHAINRELEASE FACTORSUBUNIT 1 (Halobacteriumsalinarum) |
PF03463(eRF1_1)PF03464(eRF1_2)PF03465(eRF1_3) | 5 | GLU A 306LEU A 399LEU A 320ILE A 372GLU A 328 | None | 1.15A | 5v0vA-4af1A:undetectable | 5v0vA-4af1A:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4akr | F-ACTIN-CAPPINGPROTEIN SUBUNITALPHAF-ACTIN-CAPPINGPROTEIN SUBUNIT BETA (Dictyosteliumdiscoideum) |
PF01115(F_actin_cap_B)PF01267(F-actin_cap_A) | 5 | LEU B 16LEU B 12LEU B 28ILE A 10ALA A 11 | None | 0.99A | 5v0vA-4akrB:undetectable | 5v0vA-4akrB:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b0z | 26S PROTEASOMEREGULATORY SUBUNITRPN12 (Schizosaccharomycespombe) |
PF10075(CSN8_PSD8_EIF3K) | 5 | GLU A 209LEU A 197ILE A 175ALA A 176GLU A 180 | None | 1.18A | 5v0vA-4b0zA:2.3 | 5v0vA-4b0zA:17.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d2i | HERA (Sulfolobussolfataricus) |
PF01935(DUF87)PF05872(DUF853)PF09378(HAS-barrel) | 5 | GLU A 132LEU A 135ARG A 164LEU A 161ILE A 460 | NoneNoneNoneNoneANP A1477 (-4.0A) | 1.11A | 5v0vA-4d2iA:3.4 | 5v0vA-4d2iA:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gs1 | DYP-TYPE PEROXIDASE (Thermobifidacellulosilytica) |
PF04261(Dyp_perox) | 5 | GLU A 126LEU A 138LEU A 120LEU A 201ALA A 196 | None | 1.05A | 5v0vA-4gs1A:undetectable | 5v0vA-4gs1A:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kmr | TRANSCRIPTIONALREGULATOR, LACIFAMILY (Sanguibacterkeddieii) |
PF13377(Peripla_BP_3) | 5 | GLU A 104LEU A 135LEU A 130LEU A 149GLU A 115 | None | 1.12A | 5v0vA-4kmrA:undetectable | 5v0vA-4kmrA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ks8 | SERINE/THREONINE-PROTEIN KINASE PAK 6 (Homo sapiens) |
PF00069(Pkinase) | 5 | GLU A 508LEU A 498LEU A 667LEU A 534ILE A 532 | None | 1.13A | 5v0vA-4ks8A:undetectable | 5v0vA-4ks8A:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l4i | RYANODINE RECEPTOR 2 (Mus musculus) |
PF01365(RYDR_ITPR)PF02815(MIR)PF08709(Ins145_P3_rec) | 5 | LEU A 228LEU A 277LEU A 297ILE A 363ALA A 330 | None | 1.15A | 5v0vA-4l4iA:2.1 | 5v0vA-4l4iA:22.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mbg | CAAXFARNESYLTRANSFERASEBETA SUBUNIT RAM1 (Aspergillusfumigatus) |
PF00432(Prenyltrans) | 5 | LEU B 491LEU B 124HIS B 129LEU B 411ALA B 437 | None | 1.06A | 5v0vA-4mbgB:undetectable | 5v0vA-4mbgB:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ph0 | BLV CAPSID (Bovine leukemiavirus) |
PF00607(Gag_p24) | 5 | GLU A 18LEU A 57LEU A 54ILE A 44ALA A 43 | None | 1.20A | 5v0vA-4ph0A:2.2 | 5v0vA-4ph0A:17.24 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 5 | LEU A 219LEU A 238ARG A 257LEU A 260ILE A 290 | None | 0.69A | 5v0vA-4po0A:46.0 | 5v0vA-4po0A:71.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4po0 | SERUM ALBUMIN (Oryctolaguscuniculus) |
PF00273(Serum_albumin) | 5 | LEU A 219LEU A 238HIS A 242LEU A 260ILE A 290 | None | 0.67A | 5v0vA-4po0A:46.0 | 5v0vA-4po0A:71.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ppz | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Neisseriameningitidis) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | GLU A 369LEU A 342ILE A 310ALA A 309GLU A 312 | None | 1.19A | 5v0vA-4ppzA:undetectable | 5v0vA-4ppzA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv4 | PROLINEAMINOPEPTIDASE P II (Yersinia pestis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 5 | GLU A 5LEU A 62LEU A 50LEU A 167ALA A 12 | None | 1.21A | 5v0vA-4pv4A:undetectable | 5v0vA-4pv4A:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u63 | DNA PHOTOLYASE (Agrobacteriumfabrum) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 5 | LEU A 87ARG A 82LEU A 84ILE A 39ALA A 76 | NoneSO4 A1014 (-3.5A)NoneNoneNone | 1.11A | 5v0vA-4u63A:undetectable | 5v0vA-4u63A:23.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x4w | CCA TRNANUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL (Homo sapiens) |
PF01743(PolyA_pol)PF12627(PolyA_pol_RNAbd) | 5 | LEU A 33LEU A 22LEU A 19ILE A 52GLU A 95 | None | 1.15A | 5v0vA-4x4wA:2.8 | 5v0vA-4x4wA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8i | LYSYL AMINOPEPTIDASE (Pyrococcusfuriosus) |
PF05343(Peptidase_M42) | 5 | GLU A 269LEU A 306LEU A 335ILE A 276ALA A 271 | None | 1.14A | 5v0vA-4x8iA:undetectable | 5v0vA-4x8iA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xny | HEAVY CHAIN OFANTIBODY VRC08C (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 6 | GLU H 46LEU H 82LEU H 82LEU H 20ALA H 88GLU H 40 | None | 1.31A | 5v0vA-4xnyH:undetectable | 5v0vA-4xnyH:16.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zxw | C-DOMAIN TYPE IIPEPTIDE SYNTHETASE (Streptomycesglobisporus) |
PF00668(Condensation) | 5 | GLU A 98LEU A 169LEU A 64ARG A 135LEU A 134 | None | 1.20A | 5v0vA-4zxwA:undetectable | 5v0vA-4zxwA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a1q | AF1502 (Archaeoglobusfulgidus) |
no annotation | 5 | GLU A 62LEU A 7LEU A 44LEU A 47ILE A 15 | None | 1.10A | 5v0vA-5a1qA:undetectable | 5v0vA-5a1qA:10.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aqa | OFF7_DB04V3 (syntheticconstruct) |
PF00023(Ank)PF12796(Ank_2)PF13354(Beta-lactamase2) | 5 | LEU A 181LEU A 324LEU A 320ALA A 362GLU A 342 | NoneNoneNoneNoneSCN A1422 (-4.3A) | 1.18A | 5v0vA-5aqaA:undetectable | 5v0vA-5aqaA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cdn | DNA GYRASE SUBUNIT A (Staphylococcusaureus) |
PF00521(DNA_topoisoIV) | 5 | GLU A 156LEU A 136LEU A 160LEU A 42ILE A 49 | GLU A 156 (-0.5A)LEU A 136 ( 0.5A)LEU A 160 ( 0.6A)LEU A 42 ( 0.6A)ILE A 49 ( 0.6A) | 1.18A | 5v0vA-5cdnA:undetectable | 5v0vA-5cdnA:20.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 6 | LYS A 194GLU A 195ARG A 256LEU A 259ILE A 289ALA A 290 | CL A 617 ( 4.0A)NonePG4 A 602 (-4.1A)PG4 A 602 ( 4.5A)PG4 A 602 ( 4.4A)PG4 A 602 (-3.4A) | 1.25A | 5v0vA-5dqfA:51.9 | 5v0vA-5dqfA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 8 | LYS A 194LEU A 218LEU A 237ARG A 256LEU A 259ILE A 289ALA A 290GLU A 291 | CL A 617 ( 4.0A)NonePG4 A 602 (-4.7A)PG4 A 602 (-4.1A)PG4 A 602 ( 4.5A)PG4 A 602 ( 4.4A)PG4 A 602 (-3.4A) CL A 617 ( 4.4A) | 0.43A | 5v0vA-5dqfA:51.9 | 5v0vA-5dqfA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 8 | LYS A 194LEU A 218LEU A 237HIS A 241LEU A 259ILE A 289ALA A 290GLU A 291 | CL A 617 ( 4.0A)NonePG4 A 602 (-4.7A)PG4 A 602 (-4.0A)PG4 A 602 ( 4.5A)PG4 A 602 ( 4.4A)PG4 A 602 (-3.4A) CL A 617 ( 4.4A) | 0.54A | 5v0vA-5dqfA:51.9 | 5v0vA-5dqfA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dqf | SERUM ALBUMIN (Equus caballus) |
PF00273(Serum_albumin) | 6 | TYR A 149LYS A 194LEU A 218LEU A 237HIS A 241GLU A 291 | PG4 A 602 (-4.9A) CL A 617 ( 4.0A)NonePG4 A 602 (-4.7A)PG4 A 602 (-4.0A) CL A 617 ( 4.4A) | 1.22A | 5v0vA-5dqfA:51.9 | 5v0vA-5dqfA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dz2 | GERMACRADIENOL/GEOSMIN SYNTHASE (Streptomycescoelicolor) |
no annotation | 5 | TYR A 93LEU A 132LEU A 109HIS A 105LEU A 159 | None | 1.17A | 5v0vA-5dz2A:1.6 | 5v0vA-5dz2A:20.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 6 | LEU A 219LEU A 238HIS A 242ARG A 257LEU A 260ALA A 291 | None | 0.60A | 5v0vA-5ghkA:45.2 | 5v0vA-5ghkA:76.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | LYS A 195LEU A 219LEU A 238LEU A 260ALA A 291 | None | 1.01A | 5v0vA-5ghkA:45.2 | 5v0vA-5ghkA:76.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | LYS A 199LEU A 219LEU A 238HIS A 242LEU A 260 | None | 1.12A | 5v0vA-5ghkA:45.2 | 5v0vA-5ghkA:76.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ghk | SERUM ALBUMIN (Canis lupus) |
PF00273(Serum_albumin) | 5 | TYR A 150LEU A 219LEU A 238HIS A 242ALA A 291 | None | 1.14A | 5v0vA-5ghkA:45.2 | 5v0vA-5ghkA:76.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gv0 | LYSOSOME-ASSOCIATEDMEMBRANEGLYCOPROTEIN 1 (Mus musculus) |
PF01299(Lamp) | 5 | GLU A 330LEU A 277LEU A 341LEU A 231ILE A 249 | None | 1.08A | 5v0vA-5gv0A:undetectable | 5v0vA-5gv0A:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2v | IMPORTIN SUBUNITBETA-3 (Saccharomycescerevisiae) |
PF13513(HEAT_EZ) | 5 | LEU A 140LEU A 169LEU A 163ALA A 127GLU A 128 | None | 1.14A | 5v0vA-5h2vA:2.9 | 5v0vA-5h2vA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2v | IMPORTIN SUBUNITBETA-3 (Saccharomycescerevisiae) |
PF13513(HEAT_EZ) | 5 | LEU A 169LEU A 144ILE A 126ALA A 127GLU A 128 | None | 0.95A | 5v0vA-5h2vA:2.9 | 5v0vA-5h2vA:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5irm | UNCHARACTERIZEDPROTEIN (Oryctolaguscuniculus) |
PF05729(NACHT)PF13516(LRR_6) | 5 | LEU A 609LEU A 595LEU A 535ALA A 640GLU A 636 | None | 1.14A | 5v0vA-5irmA:2.6 | 5v0vA-5irmA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5khn | RND TRANSPORTER (Burkholderiamultivorans) |
no annotation | 5 | GLU B 269LEU B 826LEU B 403ILE B 776ALA B 773 | None | 1.13A | 5v0vA-5khnB:undetectable | 5v0vA-5khnB:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd5 | TRANSKETOLASE (Chlamydomonasreinhardtii) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | TYR A 483LEU A 396LEU A 419LEU A 423ALA A 559 | None | 1.20A | 5v0vA-5nd5A:undetectable | 5v0vA-5nd5A:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0s | GLUCOSYLCERAMIDASE (Thermoanaerobacteriumxylanolyticum) |
PF04685(DUF608)PF12215(Glyco_hydr_116N)PF17168(DUF5127) | 5 | TYR A 745LEU A 540LEU A 678LEU A 680ILE A 683 | None | 1.22A | 5v0vA-5o0sA:undetectable | 5v0vA-5o0sA:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o2d | POLY [ADP-RIBOSE]POLYMERASE 14 (Homo sapiens) |
no annotation | 5 | GLU A1177LEU A1018LEU A1171ILE A1148ALA A1145 | NoneNone9HH A1201 (-4.7A)9HH A1201 ( 3.5A)None | 0.96A | 5v0vA-5o2dA:undetectable | 5v0vA-5o2dA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ogz | - (-) |
no annotation | 6 | GLU A 355LEU A 251LEU A 223LEU A 338ILE A 351ALA A 292 | None | 1.38A | 5v0vA-5ogzA:undetectable | 5v0vA-5ogzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opq | 3,6-ANHYDRO-D-GALACTOSIDASE (Zobelliagalactanivorans) |
no annotation | 5 | LEU A 654LEU A 587HIS A 630ARG A 641ILE A 667 | None | 1.10A | 5v0vA-5opqA:undetectable | 5v0vA-5opqA:8.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 5 | ARG A 256LEU A 259ILE A 289ALA A 290GLU A 291 | None | 0.80A | 5v0vA-5oriA:46.2 | 5v0vA-5oriA:75.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 5 | HIS A 241LEU A 259ILE A 289ALA A 290GLU A 291 | None | 0.66A | 5v0vA-5oriA:46.2 | 5v0vA-5oriA:75.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | LEU A 218LEU A 237ARG A 256LEU A 259ILE A 289ALA A 290 | None | 0.58A | 5v0vA-5oriA:46.2 | 5v0vA-5oriA:75.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ori | ALBUMIN (Capra hircus) |
no annotation | 6 | LEU A 218LEU A 237HIS A 241LEU A 259ILE A 289ALA A 290 | None | 0.58A | 5v0vA-5oriA:46.2 | 5v0vA-5oriA:75.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vve | PHOSPHOGLYCERATEMUTASE (Naegleriafowleri) |
PF00300(His_Phos_1) | 5 | LEU A 217LEU A 194LEU A 190ILE A 168ALA A 169 | None | 1.16A | 5v0vA-5vveA:undetectable | 5v0vA-5vveA:17.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w2f | EUKARYOTICTRANSLATIONINITIATION FACTOR 2D (Homo sapiens) |
PF01253(SUI1) | 5 | LYS A 467GLU A 466LEU A 435LEU A 455GLU A 445 | None | 0.99A | 5v0vA-5w2fA:2.1 | 5v0vA-5w2fA:18.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbl | REGULATORY-ASSOCIATED PROTEIN OF TOR 1 (Arabidopsisthaliana) |
no annotation | 5 | TYR A 159LEU A 115LEU A 113ILE A 137ALA A 135 | None | 1.10A | 5v0vA-5wblA:undetectable | 5v0vA-5wblA:8.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wze | AMINOPEPTIDASE P (Pseudomonasaeruginosa) |
no annotation | 5 | GLU A 8LEU A 65LEU A 53LEU A 169ALA A 15 | None | 1.02A | 5v0vA-5wzeA:undetectable | 5v0vA-5wzeA:8.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y9w | POLLEN RECEPTOR-LIKEKINASE 6 (Arabidopsisthaliana) |
no annotation | 5 | GLU B 183LEU B 197LEU B 199ILE B 164GLU B 187 | None | 1.20A | 5v0vA-5y9wB:undetectable | 5v0vA-5y9wB:8.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 5 | LEU A 219LEU A 238ARG A 257LEU A 260ILE A 290 | None | 0.67A | 5v0vA-5yxeA:45.3 | 5v0vA-5yxeA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 6 | LEU A 219LEU A 238HIS A 242LEU A 260ILE A 290GLU A 292 | None | 0.80A | 5v0vA-5yxeA:45.3 | 5v0vA-5yxeA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yxe | SERUM ALBUMIN (Felis catus) |
no annotation | 5 | LYS A 195LEU A 219ARG A 257LEU A 260ILE A 290 | None | 1.15A | 5v0vA-5yxeA:45.3 | 5v0vA-5yxeA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fv5 | QUEUINETRNA-RIBOSYLTRANSFERASE ACCESSORYSUBUNIT 2 (Mus musculus) |
no annotation | 5 | LYS A 128LEU A 74LEU A 136LEU A 62ALA A 68 | None | 1.07A | 5v0vA-6fv5A:undetectable | 5v0vA-6fv5A:9.87 |