SIMILAR PATTERNS OF AMINO ACIDS FOR 5V0V_A_8QPA612

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3x PYRUVATE KINASE

(Saccharomyces
cerevisiae)
PF00224
(PK)
PF02887
(PK_C)
5 LYS A   1
LEU A  10
LEU A 323
ILE A 359
ALA A 360
None
1.10A 5v0vA-1a3xA:
undetectable
5v0vA-1a3xA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a8p NADPH:FERREDOXIN
OXIDOREDUCTASE


(Azotobacter
vinelandii)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6)
5 GLU A  88
LEU A  83
LEU A  80
ILE A  40
GLU A   7
None
1.12A 5v0vA-1a8pA:
undetectable
5v0vA-1a8pA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cvr GINGIPAIN R

(Porphyromonas
gingivalis)
PF01364
(Peptidase_C25)
PF03785
(Peptidase_C25_C)
5 GLU A  21
LEU A  75
ILE A  46
ALA A  43
GLU A  44
None
1.19A 5v0vA-1cvrA:
undetectable
5v0vA-1cvrA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dvk PRP18

(Saccharomyces
cerevisiae)
PF02840
(Prp18)
5 LEU A 147
LEU A 121
ARG A 235
LEU A 236
ALA A 142
None
1.21A 5v0vA-1dvkA:
undetectable
5v0vA-1dvkA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ipi HOLLIDAY JUNCTION
RESOLVASE


(Pyrococcus
furiosus)
PF01870
(Hjc)
5 GLU A   9
LEU A 109
LEU A  16
LEU A  43
ALA A  79
None
1.08A 5v0vA-1ipiA:
undetectable
5v0vA-1ipiA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mlz 7,8-DIAMINO-PELARGON
IC ACID
AMINOTRANSFERASE


(Escherichia
coli)
PF00202
(Aminotran_3)
5 GLU A  90
LEU A  64
ILE A 326
ALA A 325
GLU A 328
None
1.20A 5v0vA-1mlzA:
undetectable
5v0vA-1mlzA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfu PROTEIN
(IMMUNOGLOBULIN
IGG1-KAPPA ANTIBODY
(HEAVY CHAIN))


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
5 LYS H  62
LEU H  82
LEU H  82
LEU H  20
GLU H  46
None
1.17A 5v0vA-1qfuH:
undetectable
5v0vA-1qfuH:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qok MFE-23 RECOMBINANT
ANTIBODY FRAGMENT


(Mus musculus)
PF07686
(V-set)
5 LYS A  89
LEU A 112
LEU A 109
LEU A  46
GLU A  72
None
1.16A 5v0vA-1qokA:
undetectable
5v0vA-1qokA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5p CIRCADIAN
OSCILLATION
REGULATOR


(Nostoc sp. PCC
7120)
PF07689
(KaiB)
5 GLU A  33
LEU A  69
LEU A  10
LEU A  12
ILE A  76
None
1.19A 5v0vA-1r5pA:
undetectable
5v0vA-1r5pA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6k PHENAZINE
BIOSYNTHESIS PROTEIN
PHZF


(Pseudomonas
fluorescens)
PF02567
(PhzC-PhzF)
5 LEU A  94
LEU A  92
LEU A 105
ILE A  81
ALA A  82
None
1.15A 5v0vA-1t6kA:
0.0
5v0vA-1t6kA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t90 PROBABLE
METHYLMALONATE-SEMIA
LDEHYDE
DEHYDROGENASE


(Bacillus
subtilis)
PF00171
(Aldedh)
5 LEU A 260
LEU A 414
ILE A 400
ALA A 399
GLU A 398
None
1.12A 5v0vA-1t90A:
undetectable
5v0vA-1t90A:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 ARG A 257
LEU A 260
ILE A 290
ALA A 291
GLU A 292
DKA  A1003 (-4.1A)
None
DKA  A1003 ( 4.5A)
CIT  A2001 ( 3.9A)
None
1.08A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 HIS A 242
LEU A 260
ILE A 290
ALA A 291
GLU A 292
DKA  A1003 (-3.7A)
None
DKA  A1003 ( 4.5A)
CIT  A2001 ( 3.9A)
None
0.96A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
6 LEU A 219
LEU A 238
ARG A 257
LEU A 260
ILE A 290
ALA A 291
None
DKA  A1003 (-4.3A)
DKA  A1003 (-4.1A)
None
DKA  A1003 ( 4.5A)
CIT  A2001 ( 3.9A)
0.57A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
6 LEU A 219
LEU A 238
HIS A 242
LEU A 260
ILE A 290
ALA A 291
None
DKA  A1003 (-4.3A)
DKA  A1003 (-3.7A)
None
DKA  A1003 ( 4.5A)
CIT  A2001 ( 3.9A)
0.60A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 LYS A 195
LEU A 219
LEU A 238
ARG A 257
LEU A 260
CIT  A2001 (-4.1A)
None
DKA  A1003 (-4.3A)
DKA  A1003 (-4.1A)
None
0.90A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 LYS A 195
LEU A 219
LEU A 238
HIS A 242
LEU A 260
CIT  A2001 (-4.1A)
None
DKA  A1003 (-4.3A)
DKA  A1003 (-3.7A)
None
1.03A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tf0 SERUM ALBUMIN

(Homo sapiens)
PF00273
(Serum_albumin)
5 LYS A 199
LEU A 219
LEU A 238
HIS A 242
LEU A 260
CIT  A2001 ( 2.7A)
None
DKA  A1003 (-4.3A)
DKA  A1003 (-3.7A)
None
1.10A 5v0vA-1tf0A:
46.0
5v0vA-1tf0A:
76.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vq0 33 KDA CHAPERONIN

(Thermotoga
maritima)
PF01430
(HSP33)
5 LEU A  35
LEU A  94
ILE A 108
ALA A 105
GLU A 135
None
1.21A 5v0vA-1vq0A:
undetectable
5v0vA-1vq0A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xtp LMAJ004091AAA

(Leishmania
major)
PF05891
(Methyltransf_PK)
5 TYR A  50
GLU A 150
LEU A 224
LEU A 214
ALA A 168
None
SAI  A 401 (-3.3A)
None
None
None
1.14A 5v0vA-1xtpA:
undetectable
5v0vA-1xtpA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzw PURPLE ACID
PHOSPHATASE


(Ipomoea batatas)
PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N)
5 TYR A 127
LEU A 283
LEU A 159
LEU A 131
ILE A 317
None
1.08A 5v0vA-1xzwA:
undetectable
5v0vA-1xzwA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ycq MDM2

(Xenopus laevis)
PF02201
(SWIB)
5 LYS A  41
LEU A 103
LEU A  30
ILE A  50
GLU A  48
None
1.00A 5v0vA-1ycqA:
undetectable
5v0vA-1ycqA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yrg GTPASE-ACTIVATING
PROTEIN RNA1_SCHPO


(Schizosaccharomyces
pombe)
no annotation 5 HIS A 186
LEU A 127
ILE A 142
ALA A 143
GLU A 178
None
1.03A 5v0vA-1yrgA:
undetectable
5v0vA-1yrgA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zzp PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1


(Homo sapiens)
PF08919
(F_actin_bind)
5 GLU A  65
LEU A  97
LEU A 101
LEU A 104
ILE A  50
None
1.21A 5v0vA-1zzpA:
3.2
5v0vA-1zzpA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9j BISPHOSPHOGLYCERATE
MUTASE


(Homo sapiens)
PF00300
(His_Phos_1)
5 LEU A 222
LEU A 199
LEU A 195
ILE A 173
ALA A 174
None
1.15A 5v0vA-2a9jA:
undetectable
5v0vA-2a9jA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bcc UBIQUINOL CYTOCHROME
C OXIDOREDUCTASE


(Gallus gallus)
PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
5 GLU A 130
LEU A 186
LEU A 122
ILE A 116
ALA A  63
None
1.18A 5v0vA-2bccA:
undetectable
5v0vA-2bccA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2chq REPLICATION FACTOR C
SMALL SUBUNIT


(Archaeoglobus
fulgidus)
PF00004
(AAA)
PF08542
(Rep_fac_C)
5 GLU A 245
LEU A 310
LEU A 313
ILE A 235
GLU A 233
None
1.22A 5v0vA-2chqA:
3.3
5v0vA-2chqA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ljw ALR2454 PROTEIN

(Nostoc sp. PCC
7120)
PF11267
(DUF3067)
5 LYS A  85
LEU A  31
LEU A  10
ILE A  74
GLU A  79
None
1.12A 5v0vA-2ljwA:
undetectable
5v0vA-2ljwA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mb9 B-CELL
LYMPHOMA/LEUKEMIA 10


(Homo sapiens)
PF00619
(CARD)
5 LEU A  72
LEU A  82
LEU A  41
ILE A  55
ALA A  65
None
1.16A 5v0vA-2mb9A:
undetectable
5v0vA-2mb9A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2py8 HYPOTHETICAL PROTEIN
RBCX


(Synechocystis
sp. PCC 6803)
PF02341
(RcbX)
5 LEU A  86
LEU A  14
ILE A  78
ALA A  79
GLU A  80
None
0.86A 5v0vA-2py8A:
undetectable
5v0vA-2py8A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdx FERREDOXIN REDUCTASE

(Pseudomonas
aeruginosa)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6)
5 GLU A  88
LEU A  83
LEU A  80
ILE A  40
GLU A   7
None
1.08A 5v0vA-2qdxA:
undetectable
5v0vA-2qdxA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qzq AXIN INTERACTOR,
DORSALIZATION
ASSOCIATED PROTEIN


(Danio rerio)
PF14186
(Aida_C2)
5 LEU A  98
LEU A  66
ILE A 104
ALA A 103
GLU A 127
None
1.13A 5v0vA-2qzqA:
undetectable
5v0vA-2qzqA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rgj FLAVIN-CONTAINING
MONOOXYGENASE


(Pseudomonas
aeruginosa)
PF01494
(FAD_binding_3)
5 GLU A  59
LEU A 113
LEU A  62
LEU A  66
ILE A  49
None
1.20A 5v0vA-2rgjA:
undetectable
5v0vA-2rgjA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whn PILUS ASSEMBLY
PROTEIN PILC


(Thermus
thermophilus)
PF00482
(T2SSF)
5 GLU A 112
LEU A  74
ILE A  90
ALA A  89
GLU A  92
None
1.12A 5v0vA-2whnA:
undetectable
5v0vA-2whnA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yvp MUTT/NUDIX FAMILY
PROTEIN


(Thermus
thermophilus)
PF00293
(NUDIX)
5 LEU A 146
ARG A  59
LEU A  57
ILE A 160
GLU A 159
None
1.15A 5v0vA-2yvpA:
undetectable
5v0vA-2yvpA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywb GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]


(Thermus
thermophilus)
PF00117
(GATase)
PF00958
(GMP_synt_C)
5 GLU A  37
LEU A 356
LEU A  27
HIS A  41
ILE A 322
None
1.20A 5v0vA-2ywbA:
undetectable
5v0vA-2ywbA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxj RAS
GTPASE-ACTIVATING
PROTEIN SYNGAP


(Rattus
norvegicus)
PF00168
(C2)
PF00616
(RasGAP)
5 GLU A 431
LEU A 416
LEU A 681
ILE A 439
ALA A 435
None
1.21A 5v0vA-3bxjA:
2.0
5v0vA-3bxjA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dra GERANYLGERANYLTRANSF
ERASE TYPE I BETA
SUBUNIT


(Candida
albicans)
PF00432
(Prenyltrans)
5 LEU B 367
LEU B   4
HIS B   9
LEU B 326
ALA B 353
None
1.13A 5v0vA-3draB:
undetectable
5v0vA-3draB:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu NON-DISCRIMINATING
AND ARCHAEAL-TYPE
ASPARTYL-TRNA
SYNTHETASE


(Thermus
thermophilus)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
5 LYS A 183
GLU A 220
LEU A 139
LEU A 237
ILE A 392
None
0.84A 5v0vA-3kfuA:
undetectable
5v0vA-3kfuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu NON-DISCRIMINATING
AND ARCHAEAL-TYPE
ASPARTYL-TRNA
SYNTHETASE


(Thermus
thermophilus)
PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
5 LYS A 183
GLU A 220
LEU A 237
ILE A 392
ALA A 391
None
1.20A 5v0vA-3kfuA:
undetectable
5v0vA-3kfuA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnt 2,3-BISPHOSPHOGLYCER
ATE-DEPENDENT
PHOSPHOGLYCERATE
MUTASE


(Burkholderia
pseudomallei)
PF00300
(His_Phos_1)
5 LEU A 216
LEU A 193
LEU A 189
ILE A 167
ALA A 168
None
1.15A 5v0vA-3lntA:
undetectable
5v0vA-3lntA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mem PUTATIVE SIGNAL
TRANSDUCTION PROTEIN


(Marinobacter
hydrocarbonoclasticus)
PF04073
(tRNA_edit)
PF08668
(HDOD)
5 TYR A 278
LEU A 183
LEU A 265
ILE A 359
ALA A 360
None
1.21A 5v0vA-3memA:
undetectable
5v0vA-3memA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkb HEMOGLOBIN SUBUNIT
ALPHA


(Isurus
oxyrinchus)
PF00042
(Globin)
5 LEU A 128
LEU A 106
LEU A 109
ALA A 123
GLU A   6
None
1.08A 5v0vA-3mkbA:
2.5
5v0vA-3mkbA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzv DECAPRENYL
DIPHOSPHATE SYNTHASE


(Rhodobacter
capsulatus)
PF00348
(polyprenyl_synt)
5 LEU A  18
LEU A 317
HIS A 315
LEU A 321
ALA A  65
None
1.19A 5v0vA-3mzvA:
undetectable
5v0vA-3mzvA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw5 TRANSGLUTAMINASE
ELICITOR


(Phytophthora
sojae)
PF16683
(TGase_elicitor)
5 TYR A 468
LEU A 185
HIS A 368
LEU A 472
GLU A 404
None
None
None
None
CXS  A   1 (-2.8A)
1.15A 5v0vA-3tw5A:
undetectable
5v0vA-3tw5A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CRISPR SYSTEM CMR
SUBUNIT CMR5


(Archaeoglobus
fulgidus)
PF09701
(Cas_Cmr5)
5 TYR F  35
LYS F 144
LEU F  94
ILE F  45
ALA F  42
None
1.18A 5v0vA-3x1lF:
undetectable
5v0vA-3x1lF:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af1 PEPTIDE CHAIN
RELEASE FACTOR
SUBUNIT 1


(Halobacterium
salinarum)
PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3)
5 GLU A 306
LEU A 399
LEU A 320
ILE A 372
GLU A 328
None
1.15A 5v0vA-4af1A:
undetectable
5v0vA-4af1A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4akr F-ACTIN-CAPPING
PROTEIN SUBUNIT
ALPHA
F-ACTIN-CAPPING
PROTEIN SUBUNIT BETA


(Dictyostelium
discoideum)
PF01115
(F_actin_cap_B)
PF01267
(F-actin_cap_A)
5 LEU B  16
LEU B  12
LEU B  28
ILE A  10
ALA A  11
None
0.99A 5v0vA-4akrB:
undetectable
5v0vA-4akrB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0z 26S PROTEASOME
REGULATORY SUBUNIT
RPN12


(Schizosaccharomyces
pombe)
PF10075
(CSN8_PSD8_EIF3K)
5 GLU A 209
LEU A 197
ILE A 175
ALA A 176
GLU A 180
None
1.18A 5v0vA-4b0zA:
2.3
5v0vA-4b0zA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d2i HERA

(Sulfolobus
solfataricus)
PF01935
(DUF87)
PF05872
(DUF853)
PF09378
(HAS-barrel)
5 GLU A 132
LEU A 135
ARG A 164
LEU A 161
ILE A 460
None
None
None
None
ANP  A1477 (-4.0A)
1.11A 5v0vA-4d2iA:
3.4
5v0vA-4d2iA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gs1 DYP-TYPE PEROXIDASE

(Thermobifida
cellulosilytica)
PF04261
(Dyp_perox)
5 GLU A 126
LEU A 138
LEU A 120
LEU A 201
ALA A 196
None
1.05A 5v0vA-4gs1A:
undetectable
5v0vA-4gs1A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kmr TRANSCRIPTIONAL
REGULATOR, LACI
FAMILY


(Sanguibacter
keddieii)
PF13377
(Peripla_BP_3)
5 GLU A 104
LEU A 135
LEU A 130
LEU A 149
GLU A 115
None
1.12A 5v0vA-4kmrA:
undetectable
5v0vA-4kmrA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ks8 SERINE/THREONINE-PRO
TEIN KINASE PAK 6


(Homo sapiens)
PF00069
(Pkinase)
5 GLU A 508
LEU A 498
LEU A 667
LEU A 534
ILE A 532
None
1.13A 5v0vA-4ks8A:
undetectable
5v0vA-4ks8A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l4i RYANODINE RECEPTOR 2

(Mus musculus)
PF01365
(RYDR_ITPR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec)
5 LEU A 228
LEU A 277
LEU A 297
ILE A 363
ALA A 330
None
1.15A 5v0vA-4l4iA:
2.1
5v0vA-4l4iA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbg CAAX
FARNESYLTRANSFERASE
BETA SUBUNIT RAM1


(Aspergillus
fumigatus)
PF00432
(Prenyltrans)
5 LEU B 491
LEU B 124
HIS B 129
LEU B 411
ALA B 437
None
1.06A 5v0vA-4mbgB:
undetectable
5v0vA-4mbgB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ph0 BLV CAPSID

(Bovine leukemia
virus)
PF00607
(Gag_p24)
5 GLU A  18
LEU A  57
LEU A  54
ILE A  44
ALA A  43
None
1.20A 5v0vA-4ph0A:
2.2
5v0vA-4ph0A:
17.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus)
PF00273
(Serum_albumin)
5 LEU A 219
LEU A 238
ARG A 257
LEU A 260
ILE A 290
None
0.69A 5v0vA-4po0A:
46.0
5v0vA-4po0A:
71.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4po0 SERUM ALBUMIN

(Oryctolagus
cuniculus)
PF00273
(Serum_albumin)
5 LEU A 219
LEU A 238
HIS A 242
LEU A 260
ILE A 290
None
0.67A 5v0vA-4po0A:
46.0
5v0vA-4po0A:
71.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppz SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE


(Neisseria
meningitidis)
PF01546
(Peptidase_M20)
PF07687
(M20_dimer)
5 GLU A 369
LEU A 342
ILE A 310
ALA A 309
GLU A 312
None
1.19A 5v0vA-4ppzA:
undetectable
5v0vA-4ppzA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pv4 PROLINE
AMINOPEPTIDASE P II


(Yersinia pestis)
PF00557
(Peptidase_M24)
PF05195
(AMP_N)
5 GLU A   5
LEU A  62
LEU A  50
LEU A 167
ALA A  12
None
1.21A 5v0vA-4pv4A:
undetectable
5v0vA-4pv4A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u63 DNA PHOTOLYASE

(Agrobacterium
fabrum)
PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7)
5 LEU A  87
ARG A  82
LEU A  84
ILE A  39
ALA A  76
None
SO4  A1014 (-3.5A)
None
None
None
1.11A 5v0vA-4u63A:
undetectable
5v0vA-4u63A:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x4w CCA TRNA
NUCLEOTIDYLTRANSFERA
SE 1, MITOCHONDRIAL


(Homo sapiens)
PF01743
(PolyA_pol)
PF12627
(PolyA_pol_RNAbd)
5 LEU A  33
LEU A  22
LEU A  19
ILE A  52
GLU A  95
None
1.15A 5v0vA-4x4wA:
2.8
5v0vA-4x4wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x8i LYSYL AMINOPEPTIDASE

(Pyrococcus
furiosus)
PF05343
(Peptidase_M42)
5 GLU A 269
LEU A 306
LEU A 335
ILE A 276
ALA A 271
None
1.14A 5v0vA-4x8iA:
undetectable
5v0vA-4x8iA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xny HEAVY CHAIN OF
ANTIBODY VRC08C


(Homo sapiens)
PF07654
(C1-set)
PF07686
(V-set)
6 GLU H  46
LEU H  82
LEU H  82
LEU H  20
ALA H  88
GLU H  40
None
1.31A 5v0vA-4xnyH:
undetectable
5v0vA-4xnyH:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxw C-DOMAIN TYPE II
PEPTIDE SYNTHETASE


(Streptomyces
globisporus)
PF00668
(Condensation)
5 GLU A  98
LEU A 169
LEU A  64
ARG A 135
LEU A 134
None
1.20A 5v0vA-4zxwA:
undetectable
5v0vA-4zxwA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1q AF1502

(Archaeoglobus
fulgidus)
no annotation 5 GLU A  62
LEU A   7
LEU A  44
LEU A  47
ILE A  15
None
1.10A 5v0vA-5a1qA:
undetectable
5v0vA-5a1qA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aqa OFF7_DB04V3

(synthetic
construct)
PF00023
(Ank)
PF12796
(Ank_2)
PF13354
(Beta-lactamase2)
5 LEU A 181
LEU A 324
LEU A 320
ALA A 362
GLU A 342
None
None
None
None
SCN  A1422 (-4.3A)
1.18A 5v0vA-5aqaA:
undetectable
5v0vA-5aqaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdn DNA GYRASE SUBUNIT A

(Staphylococcus
aureus)
PF00521
(DNA_topoisoIV)
5 GLU A 156
LEU A 136
LEU A 160
LEU A  42
ILE A  49
GLU  A 156 (-0.5A)
LEU  A 136 ( 0.5A)
LEU  A 160 ( 0.6A)
LEU  A  42 ( 0.6A)
ILE  A  49 ( 0.6A)
1.18A 5v0vA-5cdnA:
undetectable
5v0vA-5cdnA:
20.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
6 LYS A 194
GLU A 195
ARG A 256
LEU A 259
ILE A 289
ALA A 290
CL  A 617 ( 4.0A)
None
PG4  A 602 (-4.1A)
PG4  A 602 ( 4.5A)
PG4  A 602 ( 4.4A)
PG4  A 602 (-3.4A)
1.25A 5v0vA-5dqfA:
51.9
5v0vA-5dqfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
8 LYS A 194
LEU A 218
LEU A 237
ARG A 256
LEU A 259
ILE A 289
ALA A 290
GLU A 291
CL  A 617 ( 4.0A)
None
PG4  A 602 (-4.7A)
PG4  A 602 (-4.1A)
PG4  A 602 ( 4.5A)
PG4  A 602 ( 4.4A)
PG4  A 602 (-3.4A)
CL  A 617 ( 4.4A)
0.43A 5v0vA-5dqfA:
51.9
5v0vA-5dqfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
8 LYS A 194
LEU A 218
LEU A 237
HIS A 241
LEU A 259
ILE A 289
ALA A 290
GLU A 291
CL  A 617 ( 4.0A)
None
PG4  A 602 (-4.7A)
PG4  A 602 (-4.0A)
PG4  A 602 ( 4.5A)
PG4  A 602 ( 4.4A)
PG4  A 602 (-3.4A)
CL  A 617 ( 4.4A)
0.54A 5v0vA-5dqfA:
51.9
5v0vA-5dqfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5dqf SERUM ALBUMIN

(Equus caballus)
PF00273
(Serum_albumin)
6 TYR A 149
LYS A 194
LEU A 218
LEU A 237
HIS A 241
GLU A 291
PG4  A 602 (-4.9A)
CL  A 617 ( 4.0A)
None
PG4  A 602 (-4.7A)
PG4  A 602 (-4.0A)
CL  A 617 ( 4.4A)
1.22A 5v0vA-5dqfA:
51.9
5v0vA-5dqfA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dz2 GERMACRADIENOL/GEOSM
IN SYNTHASE


(Streptomyces
coelicolor)
no annotation 5 TYR A  93
LEU A 132
LEU A 109
HIS A 105
LEU A 159
None
1.17A 5v0vA-5dz2A:
1.6
5v0vA-5dz2A:
20.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
6 LEU A 219
LEU A 238
HIS A 242
ARG A 257
LEU A 260
ALA A 291
None
0.60A 5v0vA-5ghkA:
45.2
5v0vA-5ghkA:
76.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 LYS A 195
LEU A 219
LEU A 238
LEU A 260
ALA A 291
None
1.01A 5v0vA-5ghkA:
45.2
5v0vA-5ghkA:
76.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 LYS A 199
LEU A 219
LEU A 238
HIS A 242
LEU A 260
None
1.12A 5v0vA-5ghkA:
45.2
5v0vA-5ghkA:
76.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ghk SERUM ALBUMIN

(Canis lupus)
PF00273
(Serum_albumin)
5 TYR A 150
LEU A 219
LEU A 238
HIS A 242
ALA A 291
None
1.14A 5v0vA-5ghkA:
45.2
5v0vA-5ghkA:
76.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gv0 LYSOSOME-ASSOCIATED
MEMBRANE
GLYCOPROTEIN 1


(Mus musculus)
PF01299
(Lamp)
5 GLU A 330
LEU A 277
LEU A 341
LEU A 231
ILE A 249
None
1.08A 5v0vA-5gv0A:
undetectable
5v0vA-5gv0A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2v IMPORTIN SUBUNIT
BETA-3


(Saccharomyces
cerevisiae)
PF13513
(HEAT_EZ)
5 LEU A 140
LEU A 169
LEU A 163
ALA A 127
GLU A 128
None
1.14A 5v0vA-5h2vA:
2.9
5v0vA-5h2vA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2v IMPORTIN SUBUNIT
BETA-3


(Saccharomyces
cerevisiae)
PF13513
(HEAT_EZ)
5 LEU A 169
LEU A 144
ILE A 126
ALA A 127
GLU A 128
None
0.95A 5v0vA-5h2vA:
2.9
5v0vA-5h2vA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irm UNCHARACTERIZED
PROTEIN


(Oryctolagus
cuniculus)
PF05729
(NACHT)
PF13516
(LRR_6)
5 LEU A 609
LEU A 595
LEU A 535
ALA A 640
GLU A 636
None
1.14A 5v0vA-5irmA:
2.6
5v0vA-5irmA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khn RND TRANSPORTER

(Burkholderia
multivorans)
no annotation 5 GLU B 269
LEU B 826
LEU B 403
ILE B 776
ALA B 773
None
1.13A 5v0vA-5khnB:
undetectable
5v0vA-5khnB:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd5 TRANSKETOLASE

(Chlamydomonas
reinhardtii)
PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
5 TYR A 483
LEU A 396
LEU A 419
LEU A 423
ALA A 559
None
1.20A 5v0vA-5nd5A:
undetectable
5v0vA-5nd5A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0s GLUCOSYLCERAMIDASE

(Thermoanaerobacterium
xylanolyticum)
PF04685
(DUF608)
PF12215
(Glyco_hydr_116N)
PF17168
(DUF5127)
5 TYR A 745
LEU A 540
LEU A 678
LEU A 680
ILE A 683
None
1.22A 5v0vA-5o0sA:
undetectable
5v0vA-5o0sA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2d POLY [ADP-RIBOSE]
POLYMERASE 14


(Homo sapiens)
no annotation 5 GLU A1177
LEU A1018
LEU A1171
ILE A1148
ALA A1145
None
None
9HH  A1201 (-4.7A)
9HH  A1201 ( 3.5A)
None
0.96A 5v0vA-5o2dA:
undetectable
5v0vA-5o2dA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ogz -

(-)
no annotation 6 GLU A 355
LEU A 251
LEU A 223
LEU A 338
ILE A 351
ALA A 292
None
1.38A 5v0vA-5ogzA:
undetectable
5v0vA-5ogzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opq 3,6-ANHYDRO-D-GALACT
OSIDASE


(Zobellia
galactanivorans)
no annotation 5 LEU A 654
LEU A 587
HIS A 630
ARG A 641
ILE A 667
None
1.10A 5v0vA-5opqA:
undetectable
5v0vA-5opqA:
8.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 5 ARG A 256
LEU A 259
ILE A 289
ALA A 290
GLU A 291
None
0.80A 5v0vA-5oriA:
46.2
5v0vA-5oriA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 5 HIS A 241
LEU A 259
ILE A 289
ALA A 290
GLU A 291
None
0.66A 5v0vA-5oriA:
46.2
5v0vA-5oriA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 6 LEU A 218
LEU A 237
ARG A 256
LEU A 259
ILE A 289
ALA A 290
None
0.58A 5v0vA-5oriA:
46.2
5v0vA-5oriA:
75.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ori ALBUMIN

(Capra hircus)
no annotation 6 LEU A 218
LEU A 237
HIS A 241
LEU A 259
ILE A 289
ALA A 290
None
0.58A 5v0vA-5oriA:
46.2
5v0vA-5oriA:
75.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vve PHOSPHOGLYCERATE
MUTASE


(Naegleria
fowleri)
PF00300
(His_Phos_1)
5 LEU A 217
LEU A 194
LEU A 190
ILE A 168
ALA A 169
None
1.16A 5v0vA-5vveA:
undetectable
5v0vA-5vveA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w2f EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2D


(Homo sapiens)
PF01253
(SUI1)
5 LYS A 467
GLU A 466
LEU A 435
LEU A 455
GLU A 445
None
0.99A 5v0vA-5w2fA:
2.1
5v0vA-5w2fA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbl REGULATORY-ASSOCIATE
D PROTEIN OF TOR 1


(Arabidopsis
thaliana)
no annotation 5 TYR A 159
LEU A 115
LEU A 113
ILE A 137
ALA A 135
None
1.10A 5v0vA-5wblA:
undetectable
5v0vA-5wblA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wze AMINOPEPTIDASE P

(Pseudomonas
aeruginosa)
no annotation 5 GLU A   8
LEU A  65
LEU A  53
LEU A 169
ALA A  15
None
1.02A 5v0vA-5wzeA:
undetectable
5v0vA-5wzeA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9w POLLEN RECEPTOR-LIKE
KINASE 6


(Arabidopsis
thaliana)
no annotation 5 GLU B 183
LEU B 197
LEU B 199
ILE B 164
GLU B 187
None
1.20A 5v0vA-5y9wB:
undetectable
5v0vA-5y9wB:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 5 LEU A 219
LEU A 238
ARG A 257
LEU A 260
ILE A 290
None
0.67A 5v0vA-5yxeA:
45.3
5v0vA-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 6 LEU A 219
LEU A 238
HIS A 242
LEU A 260
ILE A 290
GLU A 292
None
0.80A 5v0vA-5yxeA:
45.3
5v0vA-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yxe SERUM ALBUMIN

(Felis catus)
no annotation 5 LYS A 195
LEU A 219
ARG A 257
LEU A 260
ILE A 290
None
1.15A 5v0vA-5yxeA:
45.3
5v0vA-5yxeA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fv5 QUEUINE
TRNA-RIBOSYLTRANSFER
ASE ACCESSORY
SUBUNIT 2


(Mus musculus)
no annotation 5 LYS A 128
LEU A  74
LEU A 136
LEU A  62
ALA A  68
None
1.07A 5v0vA-6fv5A:
undetectable
5v0vA-6fv5A:
9.87