SIMILAR PATTERNS OF AMINO ACIDS FOR 5UXC_A_ZITA307_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amo | NADPH-CYTOCHROMEP450 REDUCTASE (Rattusnorvegicus) |
PF00175(NAD_binding_1)PF00258(Flavodoxin_1)PF00667(FAD_binding_1) | 4 | ASP A 585GLU A 559ARG A 547THR A 589 | None | 1.45A | 5uxcA-1amoA:0.0 | 5uxcA-1amoA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c1d | L-PHENYLALANINEDEHYDROGENASE (Rhodococcus sp.) |
PF00208(ELFV_dehydrog)PF02812(ELFV_dehydrog_N) | 4 | ASP A 329GLU A 268ARG A 338THR A 332 | None | 1.17A | 5uxcA-1c1dA:0.0 | 5uxcA-1c1dA:25.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp9 | 4-ALPHA-GLUCANOTRANSFERASE (Thermusthermophilus) |
PF02446(Glyco_hydro_77) | 4 | ASP A 87PRO A 106GLU A 110ARG A 84 | None | 1.43A | 5uxcA-1fp9A:0.0 | 5uxcA-1fp9A:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fqt | RIESKE-TYPEFERREDOXIN OFBIPHENYL DIOXYGENASE (Paraburkholderiaxenovorans) |
PF00355(Rieske) | 4 | ASP A 47PRO A 82GLU A 84THR A 44 | NoneFES A1001 ( 4.4A)GOL A 901 (-4.0A)None | 1.48A | 5uxcA-1fqtA:0.0 | 5uxcA-1fqtA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gvh | FLAVOHEMOPROTEIN (Escherichiacoli) |
PF00042(Globin)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 4 | ASP A 30PRO A 22GLU A 55THR A 25 | None | 1.10A | 5uxcA-1gvhA:undetectable | 5uxcA-1gvhA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i7q | ANTHRANILATESYNTHASETRPG (Serratiamarcescens) |
PF00117(GATase)PF00425(Chorismate_bind)PF04715(Anth_synt_I_N) | 4 | ASP B 19PRO B 57ARG A 375THR B 14 | NoneGLU B1401 (-3.8A)NoneNone | 1.02A | 5uxcA-1i7qB:0.0 | 5uxcA-1i7qB:24.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jr6 | HELICASE NS3 (Hepacivirus C) |
PF00271(Helicase_C) | 4 | ASP A 106PRO A 135GLU A 137THR A 104 | None | 1.35A | 5uxcA-1jr6A:0.0 | 5uxcA-1jr6A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jx2 | MYOSIN-2 HEAVYCHAIN,DYNAMIN-A (Dictyosteliumdiscoideum) |
PF00063(Myosin_head)PF02736(Myosin_N) | 4 | ASP A 343PRO A 231GLU A 334THR A 338 | None | 1.38A | 5uxcA-1jx2A:1.1 | 5uxcA-1jx2A:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sh2 | RNA POLYMERASE (Norwalk virus) |
PF00680(RdRP_1) | 4 | PRO A 372GLU A 407ARG A 393THR A 389 | None | 1.34A | 5uxcA-1sh2A:undetectable | 5uxcA-1sh2A:20.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szq | 2-METHYLCITRATEDEHYDRATASE (Escherichiacoli) |
PF03972(MmgE_PrpD) | 4 | ASP A 397PRO A 389GLU A 326THR A 392 | None | 1.22A | 5uxcA-1szqA:0.9 | 5uxcA-1szqA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t11 | TRIGGER FACTOR (Vibrio cholerae) |
PF00254(FKBP_C)PF05697(Trigger_N)PF05698(Trigger_C) | 4 | PRO A 303GLU A 142ARG A 145THR A 143 | None | 1.50A | 5uxcA-1t11A:undetectable | 5uxcA-1t11A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u1h | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Arabidopsisthaliana) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | ASP A 409PRO A 561ARG A 411THR A 634 | None | 1.27A | 5uxcA-1u1hA:undetectable | 5uxcA-1u1hA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uwi | BETA-GALACTOSIDASE (Sulfolobussolfataricus) |
PF00232(Glyco_hydro_1) | 4 | ASP A 392GLU A 345ARG A 346THR A 356 | None | 1.41A | 5uxcA-1uwiA:undetectable | 5uxcA-1uwiA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yiq | QUINOHEMOPROTEINALCOHOLDEHYDROGENASE (Pseudomonasputida) |
PF01011(PQQ)PF13360(PQQ_2)PF13442(Cytochrome_CBB3) | 4 | ASP A 581PRO A 628GLU A 629THR A 627 | None | 1.35A | 5uxcA-1yiqA:undetectable | 5uxcA-1yiqA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yks | GENOME POLYPROTEIN[CONTAINS:FLAVIVIRIN PROTEASENS3 CATALYTICSUBUNIT] (Yellow fevervirus) |
PF00271(Helicase_C)PF07652(Flavi_DEAD) | 4 | PRO A 450GLU A 480ARG A 431THR A 432 | None | 1.49A | 5uxcA-1yksA:undetectable | 5uxcA-1yksA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2br4 | CEPHALOSPORINHYDROXYLASE CMCI (Streptomycesclavuligerus) |
PF04989(CmcI) | 4 | ASP A 214PRO A 154GLU A 178ARG A 231 | None | 1.32A | 5uxcA-2br4A:undetectable | 5uxcA-2br4A:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfm | THERMOSTABLE DNALIGASE (Pyrococcusfuriosus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | ASP A 429PRO A 456GLU A 543THR A 541 | None | 1.08A | 5uxcA-2cfmA:undetectable | 5uxcA-2cfmA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfm | THERMOSTABLE DNALIGASE (Pyrococcusfuriosus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | ASP A 538GLU A 543ARG A 544THR A 541 | None | 1.37A | 5uxcA-2cfmA:undetectable | 5uxcA-2cfmA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfm | THERMOSTABLE DNALIGASE (Pyrococcusfuriosus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | PRO A 456GLU A 543ARG A 544THR A 541 | None | 1.47A | 5uxcA-2cfmA:undetectable | 5uxcA-2cfmA:21.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m1h | TRANSCRIPTIONELONGATION FACTORS-II (Trypanosomabrucei) |
PF00855(PWWP) | 4 | ASP A 88PRO A 77GLU A 97ARG A 94 | None | 1.40A | 5uxcA-2m1hA:undetectable | 5uxcA-2m1hA:18.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyu | INOSINE TRIPHOSPHATEPYROPHOSPHATASE RDGB (Escherichiacoli) |
PF01725(Ham1p_like) | 4 | ASP A 157GLU A 175ARG A 174THR A 173 | IMP A3036 (-2.9A)NoneNoneNone | 1.21A | 5uxcA-2pyuA:undetectable | 5uxcA-2pyuA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q01 | URONATE ISOMERASE (Caulobactervibrioides) |
PF02614(UxaC) | 4 | ASP A 338PRO A 308ARG A 333THR A 334 | None | 1.33A | 5uxcA-2q01A:1.3 | 5uxcA-2q01A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdj | RETINOBLASTOMA-ASSOCIATED PROTEIN (Homo sapiens) |
PF11934(DUF3452) | 4 | ASP A 111PRO A 67GLU A 72ARG A 73 | None | 1.49A | 5uxcA-2qdjA:1.1 | 5uxcA-2qdjA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vro | ALDEHYDEDEHYDROGENASE (Paraburkholderiaxenovorans) |
PF00171(Aldedh) | 4 | ASP A 103PRO A 481GLU A 167THR A 108 | None | 1.30A | 5uxcA-2vroA:undetectable | 5uxcA-2vroA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4o | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE TYPE IV (Homo sapiens) |
PF00069(Pkinase) | 4 | ASP A 40PRO A 111GLU A 113THR A 110 | None | 1.48A | 5uxcA-2w4oA:3.7 | 5uxcA-2w4oA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xdr | BETAINE ALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | PRO A 165GLU A 464ARG A 463THR A 469 | NoneGOL A1491 (-4.3A)NoneNone | 1.27A | 5uxcA-2xdrA:undetectable | 5uxcA-2xdrA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aja | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycolicibacteriumsmegmatis) |
PF01083(Cutinase) | 4 | ASP A 160PRO A 126GLU A 149THR A 153 | None | 1.42A | 5uxcA-3ajaA:undetectable | 5uxcA-3ajaA:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aja | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycolicibacteriumsmegmatis) |
PF01083(Cutinase) | 4 | PRO A 126GLU A 149ARG A 152THR A 153 | None | 1.15A | 5uxcA-3ajaA:undetectable | 5uxcA-3ajaA:24.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8y | ENDO-PECTATE LYASE (Dickeyachrysanthemi) |
PF03211(Pectate_lyase) | 4 | ASP A 223PRO A 306GLU A 310ARG A 252 | NoneNoneNoneADA A 901 ( 3.7A) | 1.36A | 5uxcA-3b8yA:undetectable | 5uxcA-3b8yA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e53 | FATTY-ACID-COALIGASE FADD28 (Mycobacteriumtuberculosis) |
PF00501(AMP-binding) | 4 | ASP A 124PRO A 70GLU A 74THR A 119 | None | 1.42A | 5uxcA-3e53A:undetectable | 5uxcA-3e53A:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ebj | POLYMERASE ACIDICPROTEIN (Influenza Avirus) |
PF00603(Flu_PA) | 4 | ASP A 111PRO A 103GLU A 141THR A 143 | None | 1.00A | 5uxcA-3ebjA:undetectable | 5uxcA-3ebjA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1z | PUTATIVE LYSYL-TRNASYNTHETASE (Salmonellaenterica) |
PF00152(tRNA-synt_2) | 4 | ASP A 50PRO A 278GLU A 57THR A 47 | None | 1.28A | 5uxcA-3g1zA:undetectable | 5uxcA-3g1zA:22.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyr | PHENOXAZINONESYNTHASE (Streptomycesantibioticus) |
PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | ASP A 384PRO A 43GLU A 40ARG A 401 | None | 1.17A | 5uxcA-3gyrA:undetectable | 5uxcA-3gyrA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m9i | LENS FIBER MAJORINTRINSIC PROTEIN (Ovis aries) |
PF00230(MIP) | 4 | PRO A 69GLU A 16ARG A 85THR A 72 | None | 1.43A | 5uxcA-3m9iA:undetectable | 5uxcA-3m9iA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p39 | NONSTRUCTURALPROTEIN 1 (Influenza Avirus) |
PF00600(Flu_NS1) | 4 | ASP A 87GLU A 91ARG A 143THR A 89 | None | 1.42A | 5uxcA-3p39A:undetectable | 5uxcA-3p39A:20.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pkj | NAD-DEPENDENTDEACETYLASESIRTUIN-6 (Homo sapiens) |
PF02146(SIR2) | 4 | ASP A 185GLU A 138ARG A 180THR A 182 | None | 1.15A | 5uxcA-3pkjA:undetectable | 5uxcA-3pkjA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wuc | GALECTIN (Xenopus laevis) |
PF00337(Gal-bind_lectin) | 4 | ASP A 96PRO A 109GLU A 107THR A 99 | None | 1.41A | 5uxcA-3wucA:undetectable | 5uxcA-3wucA:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zg6 | NAD-DEPENDENTPROTEIN DEACETYLASESIRTUIN-6 (Homo sapiens) |
PF02146(SIR2) | 4 | ASP A 185GLU A 138ARG A 180THR A 182 | None | 1.05A | 5uxcA-3zg6A:undetectable | 5uxcA-3zg6A:24.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zyt | ESTERASE A (Paenarthrobacternitroguajacolicus) |
PF00144(Beta-lactamase) | 4 | ASP A 333PRO A 273ARG A 36THR A 263 | None | 1.45A | 5uxcA-3zytA:undetectable | 5uxcA-3zytA:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4blu | RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE J (Escherichiacoli) |
PF04378(RsmJ) | 4 | ASP A 123GLU A 140ARG A 128THR A 117 | None | 1.48A | 5uxcA-4bluA:undetectable | 5uxcA-4bluA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cog | KYNURENINEFORMAMIDASE (Burkholderiacenocepacia) |
PF04199(Cyclase) | 4 | ASP A 145PRO A 16GLU A 117ARG A 113 | None | 1.30A | 5uxcA-4cogA:undetectable | 5uxcA-4cogA:25.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f3l | BMAL1BCIRCADIAN LOCOMOTEROUTPUT CYCLESPROTEIN KAPUT (Mus musculus) |
PF00010(HLH)PF00989(PAS)PF14598(PAS_11) | 4 | ASP A 317PRO B 426GLU B 432ARG B 343 | None | 1.14A | 5uxcA-4f3lA:undetectable | 5uxcA-4f3lA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ia4 | AQUAPORIN (Spinaciaoleracea) |
PF00230(MIP) | 4 | PRO A 102GLU A 44ARG A 118THR A 105 | None | 1.33A | 5uxcA-4ia4A:0.8 | 5uxcA-4ia4A:24.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mj0 | VP1 CAPSID PROTEIN (Humanpolyomavirus 1) |
PF00718(Polyoma_coat) | 4 | ASP A 74PRO A 80GLU A 206THR A 170 | None | 1.49A | 5uxcA-4mj0A:undetectable | 5uxcA-4mj0A:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nef | AQUAPORIN-2 (Homo sapiens) |
PF00230(MIP) | 4 | PRO A 69GLU A 16ARG A 85THR A 72 | None | 1.35A | 5uxcA-4nefA:undetectable | 5uxcA-4nefA:26.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nes | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Methanocaldococcusjannaschii) |
PF02350(Epimerase_2) | 4 | ASP A 307PRO A 312ARG A 208THR A 309 | NoneNoneUDP A 401 ( 3.2A)None | 1.38A | 5uxcA-4nesA:undetectable | 5uxcA-4nesA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4opa | NONSTRUCTURALPROTEIN 1 (Influenza Avirus) |
no annotation | 4 | ASP B 87GLU B 91ARG B 143THR B 89 | None | 1.30A | 5uxcA-4opaB:undetectable | 5uxcA-4opaB:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u36 | SEED LECTIN (Vataireamacrocarpa) |
PF00139(Lectin_legB) | 4 | ASP A 87PRO A 42GLU A 78THR A 220 | TNR A 303 (-2.7A)NoneNoneNone | 1.37A | 5uxcA-4u36A:undetectable | 5uxcA-4u36A:19.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z2a | FURIN (Homo sapiens) |
PF00082(Peptidase_S8)PF01483(P_proprotein) | 4 | ASP A 526PRO A 256GLU A 257THR A 262 | None | 1.45A | 5uxcA-4z2aA:undetectable | 5uxcA-4z2aA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a0t | RIBONUCLEASE J (Streptomycescoelicolor) |
PF00753(Lactamase_B)PF07521(RMMBL) | 4 | ASP A 102GLU A 116ARG A 125THR A 128 | None | 1.38A | 5uxcA-5a0tA:undetectable | 5uxcA-5a0tA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c5x | AQUAPORIN-5 (Homo sapiens) |
PF00230(MIP) | 4 | PRO A 70GLU A 17ARG A 86THR A 73 | None | 1.36A | 5uxcA-5c5xA:undetectable | 5uxcA-5c5xA:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ca5 | NONO-1 (Caenorhabditiselegans) |
PF00076(RRM_1)PF08075(NOPS) | 4 | ASP A 158GLU A 235ARG A 160THR A 113 | None | 1.35A | 5uxcA-5ca5A:undetectable | 5uxcA-5ca5A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ckq | MANNAN-BINDINGLECTIN SERINEPROTEASE 1 (Rattusnorvegicus) |
PF00431(CUB)PF14670(FXa_inhibition) | 4 | ASP A 57PRO A 83GLU A 75ARG A 74 | CA A 305 (-2.7A)NoneNoneNone | 1.04A | 5uxcA-5ckqA:undetectable | 5uxcA-5ckqA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ckq | MANNAN-BINDINGLECTIN SERINEPROTEASE 1 (Rattusnorvegicus) |
PF00431(CUB)PF14670(FXa_inhibition) | 4 | PRO A 83GLU A 75ARG A 74THR A 82 | None | 1.09A | 5uxcA-5ckqA:undetectable | 5uxcA-5ckqA:18.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2g | DIOL DEHYDRATASE (Roseburiainulinivorans) |
PF01228(Gly_radical)PF02901(PFL-like) | 4 | ASP A 800PRO A 761GLU A 838ARG A 795 | None | 1.29A | 5uxcA-5i2gA:1.3 | 5uxcA-5i2gA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2h | O-METHYLTRANSFERASEFAMILY 2 (Planctopiruslimnophila) |
PF00891(Methyltransf_2)PF16864(Dimerisation2) | 4 | ASP A 262PRO A 258GLU A 246ARG A 219 | None | 1.50A | 5uxcA-5i2hA:1.0 | 5uxcA-5i2hA:25.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2i | REDUCED COENZYMEF420:NADPOXIDOREDUCTASE (Thermobifidafusca) |
PF03807(F420_oxidored) | 4 | ASP A 91PRO A 127GLU A 129ARG A 94 | None | 1.49A | 5uxcA-5n2iA:undetectable | 5uxcA-5n2iA:25.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o9w | THEBAINE6-O-DEMETHYLASE (Papaversomniferum) |
no annotation | 4 | ASP A 294PRO A 43ARG A 260THR A 263 | None | 1.47A | 5uxcA-5o9wA:undetectable | 5uxcA-5o9wA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oy9 | GLYCOPROTEIN GLOW-DENSITYLIPOPROTEIN RECEPTOR (Homo sapiens;Indianavesiculovirus) |
no annotation | 4 | ASP A 334GLU D 119ARG A 354THR A 352 | None CA D1001 (-2.9A)NoneNone | 0.87A | 5uxcA-5oy9A:undetectable | 5uxcA-5oy9A:10.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thz | CURJ (Mooreaproducens) |
no annotation | 4 | ASP B 315PRO B 152GLU B 322ARG B 81 | None | 1.35A | 5uxcA-5thzB:undetectable | 5uxcA-5thzB:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tx7 | D-ISOMER SPECIFIC2-HYDROXYACIDDEHYDROGENASE FAMILYPROTEIN (Desulfovibriovulgaris) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | ASP A 139GLU A 143ARG A 115THR A 141 | None | 1.44A | 5uxcA-5tx7A:undetectable | 5uxcA-5tx7A:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8e | ARGININE KINASE (Polybetespythagoricus) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 4 | ASP A 174PRO A 205GLU A 149THR A 171 | None | 1.30A | 5uxcA-5u8eA:0.2 | 5uxcA-5u8eA:23.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w1e | PUTATIVETRANSCRIPTIONALREGULATOR (Streptomycescoelicolor) |
no annotation | 4 | ASP A 209PRO A 149ARG A 146THR A 147 | NonePHB A 602 (-4.7A)NonePHB A 602 (-4.5A) | 1.39A | 5uxcA-5w1eA:undetectable | 5uxcA-5w1eA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ybl | MULTIFUNCTIONALDIOXYGENASE AUSE (Aspergillusnidulans) |
no annotation | 4 | ASP A 204GLU A 119ARG A 226THR A 158 | NoneNoneAKG A 302 (-3.0A)None | 1.44A | 5uxcA-5yblA:undetectable | 5uxcA-5yblA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cet | GATOR COMPLEXPROTEIN DEPDC5 (Homo sapiens) |
no annotation | 4 | ASP D 297GLU D 344ARG D 223THR D 300 | None | 1.41A | 5uxcA-6cetD:undetectable | 5uxcA-6cetD:12.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cri | - (-) |
no annotation | 4 | PRO M 150GLU M 162ARG M 160THR M 152 | None | 1.49A | 5uxcA-6criM:undetectable | 5uxcA-6criM:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dgk | - (-) |
no annotation | 4 | ASP A 92GLU A 96ARG A 148THR A 94 | None | 1.27A | 5uxcA-6dgkA:undetectable | 5uxcA-6dgkA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6enz | ACIDIC AMINO ACIDDECARBOXYLASE GADL1 (Mus musculus) |
no annotation | 4 | PRO A 122GLU A 118ARG A 114THR A 117 | None | 1.48A | 5uxcA-6enzA:undetectable | 5uxcA-6enzA:11.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6epd | PROTEASOME SUBUNITBETA TYPE-4 (Rattusnorvegicus) |
no annotation | 4 | ASP 7 69GLU 7 244ARG 7 88THR 7 237 | None | 1.05A | 5uxcA-6epd7:undetectable | 5uxcA-6epd7:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6esb | CAPSID PROTEIN VP1 (Humanpolyomavirus 1) |
no annotation | 4 | ASP 1 74PRO 1 80GLU 1 206THR 1 170 | None | 1.49A | 5uxcA-6esb1:undetectable | 5uxcA-6esb1:13.22 |