SIMILAR PATTERNS OF AMINO ACIDS FOR 5UUN_B_ACTB306_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f4h BETA-GALACTOSIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		4 LEU A 751
GLY A 862
SER A 861
SER A 734
 None
 0.94A 5uunB-1f4hA:
0.0		 5uunB-1f4hA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fuj PR3

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A  68
GLY A  69
SER A 117
SER A 115
 None
 1.17A 5uunB-1fujA:
undetectable		 5uunB-1fujA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5g FUSION PROTEIN

(Avian
avulavirus 1) 		PF00523
(Fusion_gly) 		4 LEU A 268
GLY A 267
SER A 265
SER A 262
 None
 1.27A 5uunB-1g5gA:
0.0		 5uunB-1g5gA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibq ASPERGILLOPEPSIN

(Aspergillus
phoenicis) 		PF00026
(Asp) 		4 LEU A 295
GLY A 294
SER A 293
SER A 291
 None
 1.25A 5uunB-1ibqA:
0.0		 5uunB-1ibqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ii0 ARSENICAL
PUMP-DRIVING ATPASE

(Escherichia
coli) 		PF02374
(ArsA_ATPase) 		4 LEU A 413
GLY A 410
SER A 161
SER A 160
 None
 1.25A 5uunB-1ii0A:
0.0		 5uunB-1ii0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5a AMIDE SYNTHASE

(Vibrio cholerae) 		PF00668
(Condensation) 		4 LEU A  33
GLY A  31
SER A 116
SER A 114
 None
 1.18A 5uunB-1l5aA:
0.0		 5uunB-1l5aA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m3g DUAL SPECIFICITY
PROTEIN PHOSPHATASE
2

(Homo sapiens) 		PF00782
(DSPc) 		4 LEU A 182
GLY A 183
SER A 184
SER A 262
 None
 1.21A 5uunB-1m3gA:
0.0		 5uunB-1m3gA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mox EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain) 		4 LEU A 243
GLY A 281
SER A 282
SER A 262
 None
 1.33A 5uunB-1moxA:
0.0		 5uunB-1moxA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mt5 FATTY-ACID AMIDE
HYDROLASE

(Rattus
norvegicus) 		PF01425
(Amidase) 		4 LEU A 266
GLY A 265
SER A 264
SER A 262
 None
 1.25A 5uunB-1mt5A:
0.0		 5uunB-1mt5A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pjz THIOPURINE
S-METHYLTRANSFERASE

(Pseudomonas
syringae) 		PF05724
(TPMT) 		4 LEU A 184
GLY A 183
SER A 180
SER A 179
 None
 1.18A 5uunB-1pjzA:
undetectable		 5uunB-1pjzA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qo0 AMIR

(Pseudomonas
aeruginosa) 		PF03861
(ANTAR) 		4 LEU D   7
GLY D   8
SER D   5
SER D   2
 None
 1.05A 5uunB-1qo0D:
undetectable		 5uunB-1qo0D:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tnu GERANYLGERANYL
TRANSFERASE TYPE I
BETA SUBUNIT

(Rattus
norvegicus) 		PF00432
(Prenyltrans) 		4 LEU B 101
GLY B 102
SER B  99
SER B  98
 None
 0.95A 5uunB-1tnuB:
undetectable		 5uunB-1tnuB:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wck BCLA PROTEIN

(Bacillus
anthracis) 		PF01391
(Collagen) 		4 LEU A 198
GLY A 149
SER A 166
SER A 165
 None
 1.12A 5uunB-1wckA:
undetectable		 5uunB-1wckA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wiv UBIQUITIN-SPECIFIC
PROTEASE 14

(Arabidopsis
thaliana) 		PF00627
(UBA) 		4 LEU A   8
GLY A   7
SER A   6
SER A   5
 None
 1.20A 5uunB-1wivA:
undetectable		 5uunB-1wivA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfd DIPEPTIDYL
AMINOPEPTIDASE-LIKE
PROTEIN 6

(Homo sapiens) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 LEU A 673
GLY A 664
SER A 665
SER A 634
 None
 1.32A 5uunB-1xfdA:
undetectable		 5uunB-1xfdA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmp PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE

(Bacillus
anthracis) 		PF00731
(AIRC) 		4 LEU A  96
GLY A  95
SER A  98
SER A 101
 None
 1.31A 5uunB-1xmpA:
undetectable		 5uunB-1xmpA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yck PEPTIDOGLYCAN
RECOGNITION PROTEIN

(Homo sapiens) 		PF01510
(Amidase_2) 		4 LEU A 162
GLY A 159
SER A 157
SER A  39
 None
 1.33A 5uunB-1yckA:
undetectable		 5uunB-1yckA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a87 THIOREDOXIN
REDUCTASE

(Mycobacterium
tuberculosis) 		PF07992
(Pyr_redox_2) 		4 LEU A 138
GLY A 139
SER A 143
SER A 144
 None
None
None
FAD  A 348 ( 4.6A)
 0.81A 5uunB-2a87A:
undetectable		 5uunB-2a87A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cf5 CINNAMYL ALCOHOL
DEHYDROGENASE

(Arabidopsis
thaliana) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 187
GLY A 188
SER A 211
SER A 212
 None
 0.90A 5uunB-2cf5A:
undetectable		 5uunB-2cf5A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 LEU A 272
GLY A 271
SER A 257
SER A 352
 None
 1.27A 5uunB-2cvtA:
undetectable		 5uunB-2cvtA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dnz PROBABLE RNA-BINDING
PROTEIN 23

(Homo sapiens) 		PF00076
(RRM_1) 		4 LEU A 231
GLY A 230
SER A 229
SER A 280
 None
 1.23A 5uunB-2dnzA:
undetectable		 5uunB-2dnzA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dou PROBABLE
N-SUCCINYLDIAMINOPIM
ELATE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 LEU A 239
GLY A 240
SER A 227
SER A 229
 None
None
SO4  A 503 (-2.7A)
SO4  A 503 (-2.6A)
 1.30A 5uunB-2douA:
undetectable		 5uunB-2douA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2l PEPTIDOGLYCAN
RECOGNITION
PROTEIN-LC ISOFORM
LCX

(Drosophila
melanogaster) 		PF01510
(Amidase_2) 		4 LEU X 486
GLY X 483
SER X 481
SER X 364
 None
None
MLD  X 201 (-3.4A)
MLD  X 201 ( 3.9A)
 1.30A 5uunB-2f2lX:
undetectable		 5uunB-2f2lX:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fi1 HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Streptococcus
pneumoniae) 		PF13419
(HAD_2) 		4 LEU A 173
GLY A 155
SER A 154
SER A 153
 None
 1.32A 5uunB-2fi1A:
undetectable		 5uunB-2fi1A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjs USG-1 PROTEIN
HOMOLOG

(Pseudomonas
aeruginosa) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 LEU A 163
GLY A 164
SER A 161
SER A 159
 None
DIO  A 407 (-3.4A)
None
None
 1.26A 5uunB-2hjsA:
undetectable		 5uunB-2hjsA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ke5 RAS-RELATED PROTEIN
RAL-B

(Homo sapiens) 		PF00071
(Ras) 		4 LEU A  91
GLY A  21
SER A  22
SER A 100
 None
 1.25A 5uunB-2ke5A:
undetectable		 5uunB-2ke5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mcz COMPLEMENT RECEPTOR
TYPE 1

(Homo sapiens) 		PF00084
(Sushi) 		4 LEU A  96
GLY A  98
SER A  99
SER A 101
 None
 1.34A 5uunB-2mczA:
undetectable		 5uunB-2mczA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n84 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei) 		PF00498
(FHA) 		4 LEU A 139
GLY A 141
SER A 157
SER A 156
 None
 1.14A 5uunB-2n84A:
undetectable		 5uunB-2n84A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qgy ENOLASE FROM THE
ENVIRONMENTAL GENOME
SHOTGUN SEQUENCING
OF THE SARGASSO SEA

(-) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 280
GLY A 279
SER A 104
SER A 275
 None
 1.27A 5uunB-2qgyA:
undetectable		 5uunB-2qgyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wb7 PT26-6P

(Thermococcus
sp. 26-2) 		no annotation 4 LEU A 520
GLY A 406
SER A 210
SER A 409
 None
 1.22A 5uunB-2wb7A:
undetectable		 5uunB-2wb7A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yum ZINC FINGER
ZZ-TYPE-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF00249
(Myb_DNA-binding) 		4 LEU A  10
GLY A   7
SER A   6
SER A   5
 None
 0.92A 5uunB-2yumA:
undetectable		 5uunB-2yumA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zjs FAB56 (HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 LEU H  52
GLY H  54
SER H  30
SER H  31
 None
 1.18A 5uunB-2zjsH:
undetectable		 5uunB-2zjsH:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1y ACIDIC RIBOSOMAL
PROTEIN P0

(Pyrococcus
horikoshii) 		PF00466
(Ribosomal_L10) 		4 LEU G 189
GLY G 188
SER G  32
SER G  31
 None
 1.31A 5uunB-3a1yG:
undetectable		 5uunB-3a1yG:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al2 DNA TOPOISOMERASE
2-BINDING PROTEIN 1

(Homo sapiens) 		PF00533
(BRCT) 		4 LEU A1372
GLY A1352
SER A1353
SER A1354
 None
 1.34A 5uunB-3al2A:
undetectable		 5uunB-3al2A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b96 VERY LONG-CHAIN
SPECIFIC ACYL-COA
DEHYDROGENASE

(Homo sapiens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LEU A 484
GLY A 483
SER A 482
SER A 480
 None
 1.33A 5uunB-3b96A:
undetectable		 5uunB-3b96A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cni PUTATIVE ABC TYPE-2
TRANSPORTER

(Thermotoga
maritima) 		no annotation 4 LEU A 158
GLY A 109
SER A 108
SER A 105
 None
 1.33A 5uunB-3cniA:
undetectable		 5uunB-3cniA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0j DNA POLYMERASE
SUBUNIT DELTA-2
DNA POLYMERASE
SUBUNIT DELTA-3

(Homo sapiens;
Homo sapiens) 		PF04042
(DNA_pol_E_B)
PF09507
(CDC27) 		4 LEU A 226
GLY A 227
SER B  97
SER B  64
 None
 1.23A 5uunB-3e0jA:
undetectable		 5uunB-3e0jA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ei8 LL-DIAMINOPIMELATE
AMINOTRANSFERASE

(Arabidopsis
thaliana) 		PF00155
(Aminotran_1_2) 		4 LEU A 279
GLY A 280
SER A 267
SER A 269
 None
None
PLP  A 433 (-2.5A)
PLP  A 433 (-2.6A)
 1.35A 5uunB-3ei8A:
undetectable		 5uunB-3ei8A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ez1 AMINOTRANSFERASE
MOCR FAMILY

(Deinococcus
geothermalis) 		PF12897
(Aminotran_MocR) 		4 LEU A 260
GLY A 261
SER A 249
SER A 251
 None
None
PO4  A 423 (-2.7A)
PO4  A 423 (-2.7A)
 1.26A 5uunB-3ez1A:
undetectable		 5uunB-3ez1A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3glq ADENOSYLHOMOCYSTEINA
SE

(Burkholderia
pseudomallei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 LEU A 179
GLY A 183
SER A 184
SER A 187
 None
 1.06A 5uunB-3glqA:
undetectable		 5uunB-3glqA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gov MASP-1

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU B 479
GLY B 481
SER B 483
SER B 561
 None
 1.31A 5uunB-3govB:
undetectable		 5uunB-3govB:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4p PROTEASOME SUBUNIT
ALPHA

(Methanocaldococcus
jannaschii) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		4 LEU A  82
GLY A  81
SER A  80
SER A 136
 None
 1.31A 5uunB-3h4pA:
undetectable		 5uunB-3h4pA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hgo 12-OXOPHYTODIENOATE
REDUCTASE 3

(Solanum
lycopersicum) 		PF00724
(Oxidored_FMN) 		4 LEU A 191
GLY A 111
SER A 127
SER A 128
 None
 1.09A 5uunB-3hgoA:
undetectable		 5uunB-3hgoA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icj UNCHARACTERIZED
METAL-DEPENDENT
HYDROLASE

(Pyrococcus
furiosus) 		PF07969
(Amidohydro_3) 		4 LEU A  86
GLY A  41
SER A  54
SER A  69
 None
 1.31A 5uunB-3icjA:
undetectable		 5uunB-3icjA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyp COMPLEMENT
DECAY-ACCELERATING
FACTOR

(Homo sapiens) 		PF00084
(Sushi) 		4 LEU F 164
GLY F 166
SER F 167
SER F 169
 None
 1.35A 5uunB-3iypF:
undetectable		 5uunB-3iypF:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3la4 UREASE

(Canavalia
ensiformis) 		PF00449
(Urease_alpha)
PF00547
(Urease_gamma)
PF00699
(Urease_beta)
PF01979
(Amidohydro_1) 		4 LEU A 491
GLY A 470
SER A 472
SER A 473
 KCX  A 490 ( 4.2A)
KCX  A 490 ( 3.5A)
None
None
 1.31A 5uunB-3la4A:
undetectable		 5uunB-3la4A:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lp6 PHOSPHORIBOSYLAMINOI
MIDAZOLE CARBOXYLASE
CATALYTIC SUBUNIT

(Mycobacterium
tuberculosis) 		PF00731
(AIRC) 		4 LEU A 101
GLY A 100
SER A 103
SER A 106
 None
 1.24A 5uunB-3lp6A:
undetectable		 5uunB-3lp6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ly9 TRANSCRIPTIONAL
ACTIVATOR CADC

(Escherichia
coli) 		no annotation 4 LEU A 194
GLY A 254
SER A 253
SER A 251
 None
 0.98A 5uunB-3ly9A:
undetectable		 5uunB-3ly9A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mgb TEG12

(uncultured soil
bacterium) 		PF00685
(Sulfotransfer_1) 		4 LEU A 256
GLY A 257
SER A 254
SER A 252
 None
 1.29A 5uunB-3mgbA:
undetectable		 5uunB-3mgbA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mwb PREPHENATE
DEHYDRATASE

(Paenarthrobacter
aurescens) 		PF00800
(PDT)
PF01842
(ACT) 		4 LEU A 141
GLY A 140
SER A 137
SER A 106
 None
 1.31A 5uunB-3mwbA:
undetectable		 5uunB-3mwbA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ng9 CAPSID PROTEIN

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		4 LEU A 379
GLY A 275
SER A 261
SER A 262
 None
 1.14A 5uunB-3ng9A:
undetectable		 5uunB-3ng9A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ol2 SEMAPHORIN-4D

(Homo sapiens) 		PF00047
(ig)
PF01403
(Sema)
PF01437
(PSI) 		4 LEU A 264
GLY A 263
SER A 383
SER A 382
 None
 0.94A 5uunB-3ol2A:
undetectable		 5uunB-3ol2A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p02 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF14274
(DUF4361)
PF16343
(DUF4973) 		4 LEU A 316
GLY A 315
SER A 186
SER A 185
 None
 1.31A 5uunB-3p02A:
undetectable		 5uunB-3p02A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p4s FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		4 LEU A 385
GLY A 384
SER A 382
SER A 381
 None
 1.35A 5uunB-3p4sA:
undetectable		 5uunB-3p4sA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p9c CAFFEIC ACID
O-METHYLTRANSFERASE

(Lolium perenne) 		PF00891
(Methyltransf_2)
PF08100
(Dimerisation) 		4 LEU A  45
GLY A 104
SER A  52
SER A 102
 None
 1.33A 5uunB-3p9cA:
undetectable		 5uunB-3p9cA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgk UREASE SUBUNIT BETA
2

(Helicobacter
mustelae) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 LEU C 219
GLY C 198
SER C 200
SER C 201
 KCX  C 218 ( 4.3A)
KCX  C 218 ( 3.6A)
None
None
 1.31A 5uunB-3qgkC:
undetectable		 5uunB-3qgkC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3se7 VANA

(-) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 LEU A 280
GLY A 281
SER A 123
SER A 124
 None
 1.19A 5uunB-3se7A:
undetectable		 5uunB-3se7A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shm CAPSID PROTEIN VP1

(Adeno-associated
dependoparvovirus
A) 		PF00740
(Parvo_coat) 		4 LEU A 379
GLY A 275
SER A 261
SER A 262
 None
 1.13A 5uunB-3shmA:
undetectable		 5uunB-3shmA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5o COMPLEMENT COMPONENT
C6

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00084
(Sushi)
PF00090
(TSP_1)
PF01823
(MACPF) 		4 LEU A 443
GLY A 442
SER A 441
SER A 440
 None
 1.11A 5uunB-3t5oA:
undetectable		 5uunB-3t5oA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v65 AGRIN

(Rattus
norvegicus) 		PF00054
(Laminin_G_1) 		4 LEU A1844
GLY A1879
SER A1880
SER A1881
 None
 1.24A 5uunB-3v65A:
undetectable		 5uunB-3v65A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v8v RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L

(Escherichia
coli) 		PF01170
(UPF0020)
PF02926
(THUMP)
PF10672
(Methyltrans_SAM) 		4 LEU A  16
GLY A  34
SER A   7
SER A  55
 None
 1.30A 5uunB-3v8vA:
undetectable		 5uunB-3v8vA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wjs NADH OXIDASE

(Gluconobacter
oxydans) 		PF00724
(Oxidored_FMN) 		4 LEU A 178
GLY A 103
SER A 117
SER A 118
 None
 1.24A 5uunB-3wjsA:
undetectable		 5uunB-3wjsA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ae0 DIPHTHERIA TOXIN

(Corynebacterium
diphtheriae) 		PF01324
(Diphtheria_R)
PF02763
(Diphtheria_C)
PF02764
(Diphtheria_T) 		4 LEU A 433
GLY A 510
SER A 508
SER A 506
 None
 1.30A 5uunB-4ae0A:
undetectable		 5uunB-4ae0A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aig ADAMALYSIN II

(Crotalus
adamanteus) 		PF01421
(Reprolysin) 		4 LEU A 158
GLY A 160
SER A 162
SER A 175
 None
 1.17A 5uunB-4aigA:
undetectable		 5uunB-4aigA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aqb MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Homo sapiens) 		PF00084
(Sushi)
PF00431
(CUB)
PF14670
(FXa_inhibition) 		4 LEU A  67
GLY A  92
SER A  69
SER A  70
 None
 1.07A 5uunB-4aqbA:
undetectable		 5uunB-4aqbA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cs8 M2-1

(Human
metapneumovirus) 		PF00642
(zf-CCCH)
PF06436
(Pneumovirus_M2) 		4 LEU A  73
GLY A  74
SER A  75
SER A  97
 None
 1.15A 5uunB-4cs8A:
undetectable		 5uunB-4cs8A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4p AMINO ACID ABC
TRANSPORTER, AMINO
ACID-BINDING/PERMEAS
E PROTEIN

(Enterococcus
faecalis) 		PF00497
(SBP_bac_3) 		4 LEU A 111
GLY A 110
SER A 204
SER A  91
 None
None
None
GLN  A 302 (-2.9A)
 1.33A 5uunB-4g4pA:
undetectable		 5uunB-4g4pA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gv1 RAC-ALPHA
SERINE/THREONINE-PRO
TEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		4 LEU A 392
GLY A 382
SER A 381
SER A 378
 None
 1.34A 5uunB-4gv1A:
undetectable		 5uunB-4gv1A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hq1 PROBABLE RECEPTOR
PROTEIN KINASE TMK1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 LEU A 110
GLY A 109
SER A 108
SER A 106
 None
 1.25A 5uunB-4hq1A:
undetectable		 5uunB-4hq1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hq1 PROBABLE RECEPTOR
PROTEIN KINASE TMK1

(Arabidopsis
thaliana) 		PF00560
(LRR_1)
PF08263
(LRRNT_2)
PF13855
(LRR_8) 		4 LEU A 254
GLY A 253
SER A 252
SER A 274
 None
 0.98A 5uunB-4hq1A:
undetectable		 5uunB-4hq1A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jre NITRITE EXTRUSION
PROTEIN 1

(Escherichia
coli) 		PF07690
(MFS_1) 		4 LEU A 364
GLY A 365
SER A 368
SER A 312
 None
 1.35A 5uunB-4jreA:
undetectable		 5uunB-4jreA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jz6 SALICYLALDEHYDE
DEHYDROGENASE NAHF

(Pseudomonas
putida) 		PF00171
(Aldedh) 		4 LEU A 257
GLY A 410
SER A 409
SER A 408
 None
 1.29A 5uunB-4jz6A:
undetectable		 5uunB-4jz6A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n7r GLUTAMYL-TRNA
REDUCTASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00745
(GlutR_dimer)
PF01488
(Shikimate_DH)
PF05201
(GlutR_N) 		4 LEU A 206
GLY A 207
SER A 258
SER A 260
 None
 1.31A 5uunB-4n7rA:
undetectable		 5uunB-4n7rA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nko ENGINEERED SCFV
HEAVY CHAIN

(Mus musculus) 		PF07686
(V-set) 		4 LEU B  45
GLY B  44
SER B  40
SER B  92
 None
 1.14A 5uunB-4nkoB:
undetectable		 5uunB-4nkoB:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ozu CORONIN

(Toxoplasma
gondii) 		PF00400
(WD40)
PF08953
(DUF1899)
PF16300
(WD40_4) 		4 LEU A 269
GLY A 284
SER A 267
SER A 266
 None
 1.07A 5uunB-4ozuA:
undetectable		 5uunB-4ozuA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qnw CHANOCLAVINE-I
ALDEHYDE REDUCTASE

(Aspergillus
fumigatus) 		PF00724
(Oxidored_FMN) 		4 LEU A 241
GLY A 236
SER A 230
SER A 227
 None
 1.10A 5uunB-4qnwA:
undetectable		 5uunB-4qnwA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uxd 2-DEHYDRO-3-DEOXY-D-
GLUCONATE/2-DEHYDRO-
3-DEOXY-PHOSPHOGLUCO
NATE ALDOLASE

(Picrophilus
torridus) 		PF00701
(DHDPS) 		4 LEU A 100
GLY A  76
SER A  77
SER A  78
 None
 1.31A 5uunB-4uxdA:
undetectable		 5uunB-4uxdA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uz1 NOTUM

(Homo sapiens) 		PF03283
(PAE) 		4 LEU A  89
GLY A 158
SER A 163
SER A 164
 None
 1.34A 5uunB-4uz1A:
undetectable		 5uunB-4uz1A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wa0 POSSIBLE ADHESIN

(Caldicellulosiruptor
kronotskyensis) 		no annotation 4 LEU A 470
GLY A 497
SER A 530
SER A 550
 None
 1.32A 5uunB-4wa0A:
undetectable		 5uunB-4wa0A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbh PROTEIN NOTUM
HOMOLOG

(Homo sapiens) 		PF03283
(PAE) 		4 LEU A  89
GLY A 158
SER A 163
SER A 164
 None
 1.35A 5uunB-4wbhA:
undetectable		 5uunB-4wbhA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x0k FAB FRAGMENT HEAVY
CHAIN

(Homo sapiens) 		no annotation 4 LEU H  45
GLY H  44
SER H  40
SER H  88
 None
 1.30A 5uunB-4x0kH:
undetectable		 5uunB-4x0kH:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z17 ENOLASE

(Chloroflexus
aurantiacus) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 LEU A 299
GLY A 296
SER A 266
SER A 265
 None
 0.86A 5uunB-4z17A:
undetectable		 5uunB-4z17A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0d SURFACE ANCHORED
PROTEIN

(Clostridium
perfringens) 		PF08341
(TED) 		4 LEU A 256
GLY A 162
SER A 163
SER A 164
 None
 1.33A 5uunB-5a0dA:
undetectable		 5uunB-5a0dA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ckq MANNAN-BINDING
LECTIN SERINE
PROTEASE 1

(Rattus
norvegicus) 		PF00431
(CUB)
PF14670
(FXa_inhibition) 		4 LEU A  48
GLY A  73
SER A  50
SER A  51
 None
 1.15A 5uunB-5ckqA:
undetectable		 5uunB-5ckqA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dwf PEPTIDOGLYCAN
RECOGNITION PROTEIN
1

(Camelus
dromedarius) 		PF01510
(Amidase_2) 		4 LEU A 159
GLY A 156
SER A 154
SER A  36
 None
 1.29A 5uunB-5dwfA:
undetectable		 5uunB-5dwfA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dxx ARTEMISINIC ALDEHYDE
DELTA(11(13))
REDUCTASE

(Artemisia annua) 		PF00724
(Oxidored_FMN) 		4 LEU A 186
GLY A 106
SER A 122
SER A 123
 None
 1.14A 5uunB-5dxxA:
undetectable		 5uunB-5dxxA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fnu KELCH-LIKE
ECH-ASSOCIATED
PROTEIN 1

(Mus musculus) 		PF01344
(Kelch_1) 		4 LEU A 365
GLY A 364
SER A 363
SER A 338
 None
L6I  A1615 (-3.1A)
L6I  A1615 (-2.9A)
None
 1.22A 5uunB-5fnuA:
undetectable		 5uunB-5fnuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gka CAPSID PROTEIN VP0

(Aichivirus A) 		PF00073
(Rhv) 		4 LEU B 325
GLY B 324
SER B 323
SER B 249
 None
 1.15A 5uunB-5gkaB:
undetectable		 5uunB-5gkaB:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gt5 PECTATE LYASE

(Paenibacillus
sp. 0602) 		no annotation 4 LEU A 102
GLY A 101
SER A 123
SER A 122
 None
 1.20A 5uunB-5gt5A:
undetectable		 5uunB-5gt5A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h35 MEMBRANE PROTEIN
TRIC

(Sulfolobus
solfataricus) 		PF03458
(UPF0126) 		4 LEU C 181
GLY C 182
SER C 183
SER C 102
 None
 1.19A 5uunB-5h35C:
undetectable		 5uunB-5h35C:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k1u NAD(P)H:FLAVIN
OXIDOREDUCTASE SYE4

(Shewanella
oneidensis) 		PF00724
(Oxidored_FMN) 		4 LEU A 282
GLY A 284
SER A 288
SER A 287
 None
 1.23A 5uunB-5k1uA:
undetectable		 5uunB-5k1uA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lhs UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR

(Mus musculus) 		no annotation 4 LEU B  68
GLY B  69
SER B 117
SER B 115
 None
 1.22A 5uunB-5lhsB:
undetectable		 5uunB-5lhsB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n9j MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 17

(Schizosaccharomyces
pombe) 		PF10156
(Med17) 		4 LEU W 243
GLY W 242
SER W 257
SER W 258
 None
 1.35A 5uunB-5n9jW:
undetectable		 5uunB-5n9jW:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuo GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN

(Novosphingobium
aromaticivorans) 		no annotation 4 LEU B  54
GLY B  55
SER B 265
SER B 266
 EDO  B 306 ( 3.4A)
EDO  B 306 ( 3.0A)
EDO  B 306 ( 3.2A)
EDO  B 306 (-2.2A)
 0.11A 5uunB-5uuoB:
46.9		 5uunB-5uuoB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x8o INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE

(Trypanosoma
brucei) 		no annotation 4 LEU A 451
GLY A 450
SER A 453
SER A 456
 None
 1.14A 5uunB-5x8oA:
undetectable		 5uunB-5x8oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyn PLATINUM SENSITIVITY
PROTEIN 3

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 103
GLY A 102
SER A  96
SER A  94
 None
 1.26A 5uunB-5xynA:
undetectable		 5uunB-5xynA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y83 MEMBRANE PROTEIN
INSERTASE YIDC

(Thermotoga
maritima) 		no annotation 4 LEU A 406
GLY A 405
SER A 404
SER A 353
 None
 1.34A 5uunB-5y83A:
undetectable		 5uunB-5y83A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ya1 AUTOINDUCER-2 KINASE

(Escherichia
coli) 		no annotation 4 LEU A 256
GLY A 252
SER A  91
SER A 172
 None
 1.08A 5uunB-5ya1A:
undetectable		 5uunB-5ya1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9s GLYCOSYL HYDROLASE
FAMILY 3 PROTEIN

(Bifidobacterium
longum) 		no annotation 4 LEU A 411
GLY A 516
SER A 561
SER A 562
 None
 1.09A 5uunB-5z9sA:
undetectable		 5uunB-5z9sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fmq -

(-) 		no annotation 4 LEU A 365
GLY A 364
SER A 363
SER A 338
 None
ACT  A 705 ( 3.9A)
ACT  A 705 ( 4.1A)
None
 1.12A 5uunB-6fmqA:
undetectable		 5uunB-6fmqA:
undetectable