SIMILAR PATTERNS OF AMINO ACIDS FOR 5UUN_A_ACTA307_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1axn ANNEXIN III

(Homo sapiens) 		PF00191
(Annexin) 		4 LEU A 118
LEU A 100
SER A 130
ALA A  97
 None
 1.14A 5uunA-1axnA:
0.0		 5uunA-1axnA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1biy LACTOFERRIN

(Bubalus bubalis) 		PF00405
(Transferrin) 		4 LEU A 687
LEU A 318
SER A 322
ALA A 317
 None
 1.13A 5uunA-1biyA:
0.3		 5uunA-1biyA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8f BENZYL ALCOHOL
DEHYDROGENASE

(Acinetobacter
calcoaceticus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 364
LEU A 204
SER A 226
ALA A 231
 None
 0.91A 5uunA-1f8fA:
undetectable		 5uunA-1f8fA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwi CYTOCHROME P450
154C1

(Streptomyces
coelicolor) 		PF00067
(p450) 		4 LEU A 402
LEU A 388
SER A 259
ALA A 385
 None
None
None
SO4  A1411 (-3.4A)
 1.02A 5uunA-1gwiA:
undetectable		 5uunA-1gwiA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hn0 CHONDROITIN ABC
LYASE I

(Proteus
vulgaris) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF09092
(Lyase_N)
PF09093
(Lyase_catalyt) 		4 LEU A 522
LEU A 264
SER A 450
ALA A 455
 None
 1.07A 5uunA-1hn0A:
3.0		 5uunA-1hn0A:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hzf COMPLEMENT FACTOR
C4A

(Homo sapiens) 		PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU A1254
LEU A1251
SER A1267
ALA A1247
 None
 1.10A 5uunA-1hzfA:
1.7		 5uunA-1hzfA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jhw MACROPHAGE CAPPING
PROTEIN

(Homo sapiens) 		PF00626
(Gelsolin) 		4 LEU A 284
LEU A 250
SER A 269
ALA A 266
 None
 1.09A 5uunA-1jhwA:
undetectable		 5uunA-1jhwA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lqa TAS PROTEIN

(Escherichia
coli) 		PF00248
(Aldo_ket_red) 		4 LEU A 306
LEU A 231
SER A  14
ALA A 303
 NDP  A1400 (-4.2A)
None
None
None
 1.05A 5uunA-1lqaA:
0.0		 5uunA-1lqaA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf7 PROTEIN (CATALASE
HPII)

(Escherichia
coli) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		4 LEU A 606
LEU A 633
SER A 659
ALA A 657
 None
 1.07A 5uunA-1qf7A:
undetectable		 5uunA-1qf7A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sb3 4-HYDROXYBENZOYL-COA
REDUCTASE GAMMA
SUBUNIT

(Thauera
aromatica) 		PF00111
(Fer2)
PF01799
(Fer2_2) 		4 LEU C  88
LEU C 115
SER C 146
ALA C 151
 None
 1.12A 5uunA-1sb3C:
undetectable		 5uunA-1sb3C:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1twy ABC TRANSPORTER,
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN

(Vibrio cholerae) 		PF12727
(PBP_like) 		4 LEU A 240
LEU A 242
SER A  65
ALA A  80
 None
None
PO4  A1500 (-2.7A)
None
 0.99A 5uunA-1twyA:
undetectable		 5uunA-1twyA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uan HYPOTHETICAL PROTEIN
TT1542

(Thermus
thermophilus) 		PF02585
(PIG-L) 		4 LEU A  64
LEU A  22
SER A  31
ALA A  25
 None
 1.15A 5uunA-1uanA:
undetectable		 5uunA-1uanA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vdw HYPOTHETICAL PROTEIN
PH1897

(Pyrococcus
horikoshii) 		PF00459
(Inositol_P) 		4 LEU A 145
LEU A 244
SER A 150
ALA A 189
 None
 1.06A 5uunA-1vdwA:
undetectable		 5uunA-1vdwA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		4 LEU C1020
LEU C1017
SER C 990
ALA C1013
 None
 0.93A 5uunA-1w36C:
undetectable		 5uunA-1w36C:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yis ADENYLOSUCCINATE
LYASE

(Caenorhabditis
elegans) 		PF00206
(Lyase_1) 		4 LEU A 351
LEU A 348
SER A 304
ALA A 344
 None
 0.99A 5uunA-1yisA:
undetectable		 5uunA-1yisA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zxq INTERCELLULAR
ADHESION MOLECULE-2

(Homo sapiens) 		PF03921
(ICAM_N) 		4 LEU A 125
LEU A 123
SER A 184
ALA A 168
 None
 1.13A 5uunA-1zxqA:
undetectable		 5uunA-1zxqA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9j BISPHOSPHOGLYCERATE
MUTASE

(Homo sapiens) 		PF00300
(His_Phos_1) 		4 LEU A  87
LEU A 165
SER A 192
ALA A 194
 None
 1.12A 5uunA-2a9jA:
undetectable		 5uunA-2a9jA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adz ALPHA-1-SYNTROPHIN

(Mus musculus) 		no annotation 4 LEU A  12
LEU A 144
SER A 164
ALA A 169
 None
 1.10A 5uunA-2adzA:
undetectable		 5uunA-2adzA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2be7 ASPARTATE
CARBAMOYLTRANSFERASE
CATALYTIC CHAIN

(Moritella
profunda) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A 225
LEU A 261
SER A 253
ALA A 257
 None
 1.01A 5uunA-2be7A:
undetectable		 5uunA-2be7A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cq2 HYPOTHETICAL PROTEIN
LOC91801

(Homo sapiens) 		PF00076
(RRM_1) 		4 LEU A  61
LEU A  65
SER A  83
ALA A  85
 None
 1.11A 5uunA-2cq2A:
undetectable		 5uunA-2cq2A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0d 2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE

(Pseudomonas
fluorescens) 		PF00561
(Abhydrolase_1) 		4 LEU A 108
LEU A 202
SER A  77
ALA A 201
 None
 1.02A 5uunA-2d0dA:
undetectable		 5uunA-2d0dA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fj0 CARBOXYLIC ESTER
HYDROLASE

(Manduca sexta) 		PF00135
(COesterase) 		4 LEU A 331
LEU A 196
SER A 255
ALA A 231
 None
 1.13A 5uunA-2fj0A:
undetectable		 5uunA-2fj0A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fy2 CHOLINE
O-ACETYLTRANSFERASE

(Homo sapiens) 		PF00755
(Carn_acyltransf) 		4 LEU A 235
LEU A 234
SER A 379
ALA A 381
 None
 1.13A 5uunA-2fy2A:
undetectable		 5uunA-2fy2A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggs 273AA LONG
HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE REDUCTASE

(Sulfurisphaera
tokodaii) 		PF04321
(RmlD_sub_bind) 		4 LEU A 199
LEU A 196
SER A 260
ALA A 192
 None
 1.03A 5uunA-2ggsA:
undetectable		 5uunA-2ggsA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2q BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Trypanosoma
cruzi) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		4 LEU A 420
LEU A 456
SER A 437
ALA A 439
 None
 0.89A 5uunA-2h2qA:
undetectable		 5uunA-2h2qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7a CALPAIN 13

(Homo sapiens) 		no annotation 4 LEU A 566
LEU A 521
SER A 545
ALA A 518
 None
 1.05A 5uunA-2i7aA:
undetectable		 5uunA-2i7aA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7g MONOOXYGENASE

(Agrobacterium
fabrum) 		PF00296
(Bac_luciferase) 		4 LEU A 211
LEU A 214
SER A 185
ALA A 187
 None
None
SO4  A 702 (-2.7A)
None
 0.88A 5uunA-2i7gA:
undetectable		 5uunA-2i7gA:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oip CHAIN A, CRYSTAL
STRUCTURE OF DHFR

(Cryptosporidium
hominis) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		4 LEU A 420
LEU A 456
SER A 437
ALA A 439
 None
 1.03A 5uunA-2oipA:
undetectable		 5uunA-2oipA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph1 NUCLEOTIDE-BINDING
PROTEIN

(Archaeoglobus
fulgidus) 		PF10609
(ParA) 		4 LEU A 165
LEU A 187
SER A 213
ALA A 215
 None
 1.13A 5uunA-2ph1A:
undetectable		 5uunA-2ph1A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppy ENOYL-COA HYDRATASE

(Geobacillus
kaustophilus) 		PF00378
(ECH_1) 		4 LEU A 237
LEU A 241
SER A 213
ALA A 211
 None
 1.11A 5uunA-2ppyA:
undetectable		 5uunA-2ppyA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qty POLY(ADP-RIBOSE)
GLYCOHYDROLASE ARH3

(Mus musculus) 		PF03747
(ADP_ribosyl_GH) 		4 LEU A  69
LEU A  73
SER A 145
ALA A 147
 None
 0.99A 5uunA-2qtyA:
undetectable		 5uunA-2qtyA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2quq CENTROMERE
DNA-BINDING PROTEIN
COMPLEX CBF3 SUBUNIT
B

(Saccharomyces
cerevisiae) 		PF16846
(Cep3) 		4 LEU A 220
LEU A 217
SER A 165
ALA A 213
 None
 0.84A 5uunA-2quqA:
1.8		 5uunA-2quqA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qwz PHENYLACETIC ACID
DEGRADATION-RELATED
PROTEIN

(Ruegeria sp.
TM1040) 		PF03061
(4HBT) 		4 LEU A  98
LEU A 118
SER A  56
ALA A  61
 None
None
ACT  A 141 (-2.7A)
None
 1.07A 5uunA-2qwzA:
undetectable		 5uunA-2qwzA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r94 2-KETO-3-DEOXY-(6-PH
OSPHO-)GLUCONATE
ALDOLASE

(Thermoproteus
tenax) 		PF00701
(DHDPS) 		4 LEU A 247
LEU A 225
SER A 216
ALA A 218
 None
 0.93A 5uunA-2r94A:
undetectable		 5uunA-2r94A:
25.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3k LEUCYL/PHENYLALANYL-
TRNA-PROTEIN
TRANSFERASE

(Escherichia
coli) 		PF03588
(Leu_Phe_trans) 		4 LEU A  72
LEU A  67
SER A 196
ALA A 199
 None
 0.94A 5uunA-2z3kA:
undetectable		 5uunA-2z3kA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce9 GLYCEROL
DEHYDROGENASE

(Clostridium
acetobutylicum) 		PF13685
(Fe-ADH_2) 		4 LEU A 260
LEU A 256
SER A 309
ALA A 314
 None
 1.04A 5uunA-3ce9A:
undetectable		 5uunA-3ce9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgg SAM-DEPENDENT
METHYLTRANSFERASE

(Corynebacterium
glutamicum) 		PF13649
(Methyltransf_25) 		4 LEU A  71
LEU A  50
SER A 103
ALA A 135
 None
None
EDO  A 200 ( 2.7A)
None
 0.75A 5uunA-3cggA:
undetectable		 5uunA-3cggA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3co8 ALANINE RACEMASE

(Oenococcus oeni) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 LEU A  36
LEU A  34
SER A 203
ALA A 220
 None
None
PLP  A 401 (-2.6A)
None
 0.99A 5uunA-3co8A:
undetectable		 5uunA-3co8A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqc NUCLEAR PORE COMPLEX
PROTEIN NUP133

(Homo sapiens) 		no annotation 4 LEU B 956
LEU B 953
SER B 936
ALA B 949
 None
 0.93A 5uunA-3cqcB:
undetectable		 5uunA-3cqcB:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbx CD1-2 ANTIGEN

(Gallus gallus) 		PF07654
(C1-set)
PF16497
(MHC_I_3) 		4 LEU A 206
LEU A 256
SER A 237
ALA A 235
 None
 0.95A 5uunA-3dbxA:
undetectable		 5uunA-3dbxA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbf PHPD

(Streptomyces
viridochromogenes) 		no annotation 4 LEU A 283
LEU A 279
SER A 248
ALA A 250
 None
 1.11A 5uunA-3gbfA:
undetectable		 5uunA-3gbfA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdi PERIOD CIRCADIAN
PROTEIN HOMOLOG 2

(Mus musculus) 		PF08447
(PAS_3) 		4 LEU A 311
LEU A 309
SER A 206
ALA A 194
 None
 0.83A 5uunA-3gdiA:
undetectable		 5uunA-3gdiA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyx ADENYLYLSULFATE
REDUCTASE

(Desulfovibrio
gigas) 		PF00890
(FAD_binding_2) 		4 LEU A  57
LEU A  28
SER A  24
ALA A 224
 None
 1.07A 5uunA-3gyxA:
undetectable		 5uunA-3gyxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhd FATTY ACID SYNTHASE

(Homo sapiens) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		4 LEU A 829
LEU A 346
SER A  10
ALA A 342
 None
 1.08A 5uunA-3hhdA:
undetectable		 5uunA-3hhdA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hv9 PROTEIN FIMX

(Pseudomonas
aeruginosa) 		PF00563
(EAL) 		4 LEU A 562
LEU A 557
SER A 514
ALA A 519
 None
 1.10A 5uunA-3hv9A:
undetectable		 5uunA-3hv9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4r NUCLEAR PORE COMPLEX
PROTEIN NUP133

(Homo sapiens) 		PF03177
(Nucleoporin_C) 		4 LEU B 956
LEU B 953
SER B 936
ALA B 949
 None
 1.04A 5uunA-3i4rB:
1.7		 5uunA-3i4rB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ipl 2-SUCCINYLBENZOATE--
COA LIGASE

(Staphylococcus
aureus) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 284
LEU A 320
SER A 302
ALA A 315
 None
 1.14A 5uunA-3iplA:
undetectable		 5uunA-3iplA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kb3 PROTEIN PHOSPHATASE
2C 16

(Arabidopsis
thaliana) 		PF00481
(PP2C) 		4 LEU B 262
LEU B 333
SER B 342
ALA B 332
 None
 1.04A 5uunA-3kb3B:
undetectable		 5uunA-3kb3B:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kv1 TRANSCRIPTIONAL
REPRESSOR

(Aliivibrio
fischeri) 		PF04198
(Sugar-bind) 		4 LEU A 256
LEU A 246
SER A 249
ALA A 247
 None
 1.11A 5uunA-3kv1A:
undetectable		 5uunA-3kv1A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l8j PROGRAMMED CELL
DEATH PROTEIN 10

(Homo sapiens) 		PF06840
(DUF1241) 		4 LEU A 110
LEU A 114
SER A 171
ALA A 194
 None
 0.99A 5uunA-3l8jA:
3.0		 5uunA-3l8jA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Streptococcus
pyogenes) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A  63
LEU A 211
SER A 197
ALA A 188
 None
 1.12A 5uunA-3lgxA:
undetectable		 5uunA-3lgxA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc6 SPHINGOSINE-1-PHOSPH
ATE LYASE

(Saccharomyces
cerevisiae) 		PF00282
(Pyridoxal_deC) 		4 LEU C 491
LEU C 511
SER C 483
ALA C 510
 None
 0.74A 5uunA-3mc6C:
undetectable		 5uunA-3mc6C:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3os6 ISOCHORISMATE
SYNTHASE DHBC

(Bacillus
anthracis) 		PF00425
(Chorismate_bind) 		4 LEU A 253
LEU A 299
SER A 201
ALA A 296
 None
None
15P  A 408 ( 4.0A)
None
 1.13A 5uunA-3os6A:
undetectable		 5uunA-3os6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q98 TRANSCARBAMYLASE

(Escherichia
coli) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		4 LEU A  35
LEU A  39
SER A 169
ALA A 174
 None
 1.06A 5uunA-3q98A:
undetectable		 5uunA-3q98A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t94 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE
(MTAP)

(Sulfolobus
solfataricus) 		PF01048
(PNP_UDP_1) 		4 LEU A 250
LEU A 246
SER A 140
ALA A 145
 None
 1.05A 5uunA-3t94A:
undetectable		 5uunA-3t94A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v7i PUTATIVE POLYKETIDE
SYNTHASE

(Streptomyces
coelicolor) 		PF00195
(Chal_sti_synt_N) 		4 LEU A   5
LEU A 246
SER A 181
ALA A 186
 None
 1.09A 5uunA-3v7iA:
undetectable		 5uunA-3v7iA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5a NUCLEOSIDE-TRIPHOSPH
ATASE 1

(Toxoplasma
gondii) 		PF01150
(GDA1_CD39) 		4 LEU A 156
LEU A 152
SER A  75
ALA A 110
 None
None
ANP  A 700 ( 4.7A)
None
 1.11A 5uunA-4a5aA:
undetectable		 5uunA-4a5aA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		4 LEU B2992
LEU B2923
SER B2916
ALA B2920
 None
 1.15A 5uunA-4bedB:
undetectable		 5uunA-4bedB:
9.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4clc UPF0303 PROTEIN
YBR137W

(Saccharomyces
cerevisiae) 		PF03928
(Haem_degrading) 		4 LEU E  42
LEU E  31
SER E 163
ALA E 168
 None
 1.12A 5uunA-4clcE:
undetectable		 5uunA-4clcE:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddq DNA GYRASE SUBUNIT A

(Bacillus
subtilis) 		PF00521
(DNA_topoisoIV) 		4 LEU A 410
LEU A 425
SER A 400
ALA A 403
 None
 1.08A 5uunA-4ddqA:
undetectable		 5uunA-4ddqA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei8 PLASMID REPLICATION
PROTEIN REPX

(Bacillus cereus) 		PF00091
(Tubulin) 		4 LEU A 290
LEU A 360
SER A 296
ALA A 358
 None
 1.10A 5uunA-4ei8A:
undetectable		 5uunA-4ei8A:
22.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f0b THIOL TRANSFERASE

(Phanerochaete
chrysosporium) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A  89
LEU A 119
SER A 102
ALA A 179
 None
 1.08A 5uunA-4f0bA:
25.4		 5uunA-4f0bA:
30.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fl3 TYROSINE-PROTEIN
KINASE SYK

(Homo sapiens) 		PF00017
(SH2)
PF07714
(Pkinase_Tyr) 		4 LEU A 205
LEU A 251
SER A 245
ALA A 248
 None
 1.12A 5uunA-4fl3A:
undetectable		 5uunA-4fl3A:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g56 HSL7 PROTEIN

(Xenopus laevis) 		PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C) 		4 LEU A 561
LEU A 555
SER A 331
ALA A 336
 None
 1.01A 5uunA-4g56A:
undetectable		 5uunA-4g56A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6t TYPE III CHAPERONE
PROTEIN SHCA
TYPE III EFFECTOR
HOPA1

(Pseudomonas
syringae group
genomosp. 3;
Pseudomonas
syringae group
genomosp. 3) 		PF05932
(CesT)
no annotation 		4 LEU A  91
LEU A  56
SER B  56
ALA B  58
 None
 1.01A 5uunA-4g6tA:
undetectable		 5uunA-4g6tA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gqb PROTEIN ARGININE
N-METHYLTRANSFERASE
5

(Homo sapiens) 		PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C) 		4 LEU A 565
LEU A 559
SER A 335
ALA A 340
 None
 1.02A 5uunA-4gqbA:
undetectable		 5uunA-4gqbA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb6 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Pseudomonas
aeruginosa) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 LEU A 209
LEU A 200
SER A 233
ALA A 195
 None
 1.12A 5uunA-4jb6A:
undetectable		 5uunA-4jb6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbu VIRULENCE-ASSOCIATED
V ANTIGEN

(Yersinia pestis) 		PF04792
(LcrV) 		4 LEU A  75
LEU A  79
SER A  30
ALA A  83
 None
 1.03A 5uunA-4jbuA:
undetectable		 5uunA-4jbuA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6d TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Desulfovibrio
salexigens) 		PF03480
(DctP) 		4 LEU A 161
LEU A 164
SER A 181
ALA A 184
 None
 0.93A 5uunA-4n6dA:
undetectable		 5uunA-4n6dA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n8y PUTATIVE TRAP-TYPE
C4-DICARBOXYLATE
TRANSPORT SYSTEM,
BINDING PERIPLASMIC
PROTEIN (DCTP
SUBUNIT)

(Bradyrhizobium
sp. BTAi1) 		PF03480
(DctP) 		4 LEU A 157
LEU A 160
SER A 179
ALA A 182
 None
 1.01A 5uunA-4n8yA:
undetectable		 5uunA-4n8yA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6i NUCLEOPROTEIN

(Lymphocytic
choriomeningitis
mammarenavirus) 		PF17290
(Arena_ncap_C) 		4 LEU A 358
LEU A 366
SER A 440
ALA A 445
 None
 1.02A 5uunA-4o6iA:
undetectable		 5uunA-4o6iA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rk1 RIBOSE
TRANSCRIPTIONAL
REGULATOR

(Enterococcus
faecium) 		PF13377
(Peripla_BP_3) 		4 LEU A 179
LEU A 182
SER A 334
ALA A 336
 None
 1.06A 5uunA-4rk1A:
undetectable		 5uunA-4rk1A:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tkr THIAMINE TRANSPORTER
THIA

(Listeria
monocytogenes) 		PF09515
(Thia_YuaJ) 		4 LEU A  63
LEU A  60
SER A  88
ALA A  57
 None
 1.13A 5uunA-4tkrA:
undetectable		 5uunA-4tkrA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4txg CHITINASE

(Chromobacterium
violaceum) 		PF00704
(Glyco_hydro_18)
PF06483
(ChiC) 		4 LEU A 628
LEU A 631
SER A 584
ALA A 586
 None
 0.99A 5uunA-4txgA:
undetectable		 5uunA-4txgA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb6 ALPHA-D-RIBOSE
1-METHYLPHOSPHONATE
5-TRIPHOSPHATE
SYNTHASE SUBUNIT
PHNH

(Escherichia
coli) 		PF05845
(PhnH) 		4 LEU B 125
LEU B 123
SER B  65
ALA B  95
 None
 0.95A 5uunA-4xb6B:
undetectable		 5uunA-4xb6B:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xri PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 LEU A 692
LEU A 654
SER A 671
ALA A 666
 None
 1.14A 5uunA-4xriA:
4.5		 5uunA-4xriA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z7e LMO1422 PROTEIN

(Listeria
monocytogenes) 		PF04069
(OpuAC) 		4 LEU A 353
LEU A 432
SER A 344
ALA A 342
 None
 1.08A 5uunA-4z7eA:
undetectable		 5uunA-4z7eA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zlv ORNITHINE
AMINOTRANSFERASE,
MITOCHONDRIAL,
PUTATIVE

(Toxoplasma
gondii) 		PF00202
(Aminotran_3) 		4 LEU A 334
LEU A 331
SER A 287
ALA A 327
 None
 1.01A 5uunA-4zlvA:
undetectable		 5uunA-4zlvA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aqa OFF7_DB04V3

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13354
(Beta-lactamase2) 		4 LEU A 267
LEU A 252
SER A 236
ALA A 255
 None
 1.14A 5uunA-5aqaA:
undetectable		 5uunA-5aqaA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fic SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		4 LEU A 351
LEU A 367
SER A 377
ALA A 366
 None
 1.04A 5uunA-5ficA:
undetectable		 5uunA-5ficA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g6r IMINE REDUCTASE

(Aspergillus
oryzae) 		PF03446
(NAD_binding_2) 		4 LEU A  80
LEU A  83
SER A 108
ALA A 111
 None
 1.06A 5uunA-5g6rA:
undetectable		 5uunA-5g6rA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gw5 T-COMPLEX PROTEIN 1
SUBUNIT BETA

(Saccharomyces
cerevisiae) 		PF00118
(Cpn60_TCP1) 		4 LEU b  98
LEU b 102
SER b 500
ALA b 505
 None
 1.10A 5uunA-5gw5b:
undetectable		 5uunA-5gw5b:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hqn SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		4 LEU A 351
LEU A 367
SER A 377
ALA A 366
 None
 0.97A 5uunA-5hqnA:
undetectable		 5uunA-5hqnA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hx9 BETA-LACTAMASE

(Burkholderia
vietnamiensis) 		PF13354
(Beta-lactamase2) 		4 LEU A 137
LEU A 122
SER A 106
ALA A 125
 None
 1.13A 5uunA-5hx9A:
undetectable		 5uunA-5hx9A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i85 SPHINGOMYELIN
PHOSPHODIESTERASE

(Homo sapiens) 		PF00149
(Metallophos) 		4 LEU A 353
LEU A 369
SER A 379
ALA A 368
 None
 1.09A 5uunA-5i85A:
undetectable		 5uunA-5i85A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ify GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E

(Burkholderia
vietnamiensis) 		PF00483
(NTP_transferase) 		4 LEU A 118
LEU A 122
SER A  41
ALA A  46
 UMP  A 501 ( 4.4A)
None
UMP  A 501 ( 4.9A)
None
 0.91A 5uunA-5ifyA:
undetectable		 5uunA-5ifyA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jpn COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF01821
(ANATO)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU B1273
LEU B1270
SER B1286
ALA B1266
 None
 1.14A 5uunA-5jpnB:
5.8		 5uunA-5jpnB:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqx GLUCOSYL-3-PHOSPHOGL
YCERATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00535
(Glycos_transf_2) 		4 LEU A 194
LEU A 278
SER A 270
ALA A 275
 None
 1.10A 5uunA-5jqxA:
undetectable		 5uunA-5jqxA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jtw COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU B1270
LEU B1273
SER B1313
ALA B1318
 None
 1.10A 5uunA-5jtwB:
4.2		 5uunA-5jtwB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jtw COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 LEU B1273
LEU B1270
SER B1286
ALA B1266
 None
 1.09A 5uunA-5jtwB:
4.2		 5uunA-5jtwB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l94 CYTOCHROME P450

(Bacillus
megaterium) 		PF00067
(p450) 		4 LEU A 369
LEU A 366
SER A 139
ALA A 362
 None
 1.02A 5uunA-5l94A:
undetectable		 5uunA-5l94A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m59 PRE-MRNA SPLICING
HELICASE-LIKE
PROTEIN

(Chaetomium
thermophilum) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02889
(Sec63) 		4 LEU A 947
LEU A 951
SER A1008
ALA A1010
 None
 0.94A 5uunA-5m59A:
undetectable		 5uunA-5m59A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o00 GLUTATHIONE
TRANSFERASE URE2P5

(Phanerochaete
chrysosporium) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A  79
LEU A 106
SER A  92
ALA A 169
 None
 1.13A 5uunA-5o00A:
22.3		 5uunA-5o00A:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5or4 CATECHOL OXIDASE

(Aspergillus
oryzae) 		no annotation 4 LEU A  52
LEU A  49
SER A  35
ALA A  37
 None
 0.91A 5uunA-5or4A:
undetectable		 5uunA-5or4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tzy FREE FATTY ACID
RECEPTOR
1,ENDOLYSIN,FREE
FATTY ACID RECEPTOR
1

(Homo sapiens;
Escherichia
virus T4) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 LEU A  55
LEU A  59
SER A2268
ALA A  15
 None
 1.05A 5uunA-5tzyA:
undetectable		 5uunA-5tzyA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuo GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN

(Novosphingobium
aromaticivorans) 		no annotation 4 LEU B  54
LEU B  83
SER B 265
ALA B 270
 EDO  B 306 ( 3.4A)
EDO  B 309 ( 3.5A)
EDO  B 306 ( 3.2A)
EDO  B 309 ( 3.0A)
 0.99A 5uunA-5uuoB:
45.5		 5uunA-5uuoB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uuo GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN

(Novosphingobium
aromaticivorans) 		no annotation 4 LEU B  54
LEU B  83
SER B 266
ALA B 270
 EDO  B 306 ( 3.4A)
EDO  B 309 ( 3.5A)
EDO  B 306 (-2.2A)
EDO  B 309 ( 3.0A)
 0.21A 5uunA-5uuoB:
45.5		 5uunA-5uuoB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vbb RNA PSEUDOURIDYLATE
SYNTHASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00849
(PseudoU_synth_2) 		4 LEU A 148
LEU A 166
SER A 162
ALA A 101
 None
 1.13A 5uunA-5vbbA:
undetectable		 5uunA-5vbbA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xrt -

(-) 		no annotation 4 LEU A 118
LEU A  66
SER A 115
ALA A 113
 None
 1.11A 5uunA-5xrtA:
undetectable		 5uunA-5xrtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ep3 -

(-) 		no annotation 4 LEU A  70
LEU A  31
SER A  61
ALA A  68
 None
 1.13A 5uunA-6ep3A:
undetectable		 5uunA-6ep3A:
undetectable