SIMILAR PATTERNS OF AMINO ACIDS FOR 5UTU_H_ADNH503_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9x CARBAMOYL PHOSPHATE
SYNTHETASE (SMALL
CHAIN)

(Escherichia
coli) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain) 		4 THR B1565
GLU B1541
HIS B1791
LEU B1555
 None
 1.12A 5utuH-1a9xB:
2.4		 5utuH-1a9xB:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9o PROTEIN
(ALPHA-LACTALBUMIN)

(Homo sapiens) 		PF00062
(Lys) 		4 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.30A 5utuH-1b9oA:
undetectable		 5utuH-1b9oA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgs DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 THR A 219
GLU A 114
THR A 112
LEU A 242
 None
AMP  A 700 (-3.7A)
None
None
 1.25A 5utuH-1dgsA:
2.3		 5utuH-1dgsA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hfy ALPHA-LACTALBUMIN

(Capra hircus) 		PF00062
(Lys) 		4 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.19A 5utuH-1hfyA:
undetectable		 5utuH-1hfyA:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hml ALPHA-LACTALBUMIN

(Homo sapiens) 		PF00062
(Lys) 		4 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
ZN  A 125 ( 2.1A)
None
None
 1.23A 5utuH-1hmlA:
undetectable		 5utuH-1hmlA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7f HEAT SHOCK PROTEIN
33

(Escherichia
coli) 		PF01430
(HSP33) 		4 THR A 137
GLU A 143
THR A 154
LEU A  57
 None
 1.23A 5utuH-1i7fA:
undetectable		 5utuH-1i7fA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i8q HYALURONATE LYASE

(Streptococcus
agalactiae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		4 THR A 453
GLU A 440
THR A 402
LEU A 256
 None
 1.17A 5utuH-1i8qA:
undetectable		 5utuH-1i8qA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9a CARBOXYL-TERMINAL
SRC KINASE

(Rattus
norvegicus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 THR A 229
GLU A 108
HIS A 128
LEU A 105
 None
 1.32A 5utuH-1k9aA:
undetectable		 5utuH-1k9aA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1krh BENZOATE
1,2-DIOXYGENASE
REDUCTASE

(Acinetobacter
sp.) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		4 THR A  48
THR A 104
HIS A 138
LEU A 140
 None
 1.29A 5utuH-1krhA:
3.1		 5utuH-1krhA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kyh HYPOTHETICAL 29.9
KDA PROTEIN IN
SIGY-CYDD INTERGENIC
REGION

(Bacillus
subtilis) 		PF01256
(Carb_kinase) 		4 THR A 204
THR A 217
HIS A 262
LEU A 259
 None
 0.97A 5utuH-1kyhA:
3.7		 5utuH-1kyhA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n8p CYSTATHIONINE
GAMMA-LYASE

(Saccharomyces
cerevisiae) 		PF01053
(Cys_Met_Meta_PP) 		4 THR A 106
GLU A 145
THR A 146
LEU A 175
 None
PLP  A 400 ( 4.7A)
None
None
 1.31A 5utuH-1n8pA:
undetectable		 5utuH-1n8pA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nf5 ALPHA-LACTALBUMIN

(Mus musculus) 		PF00062
(Lys) 		4 THR A  33
GLU A  49
THR A  48
LEU A  81
 None
 1.18A 5utuH-1nf5A:
undetectable		 5utuH-1nf5A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1noz DNA POLYMERASE

(Escherichia
virus T4) 		PF03104
(DNA_pol_B_exo1) 		4 THR A 280
GLU A 294
THR A 295
LEU A 287
 None
 1.25A 5utuH-1nozA:
undetectable		 5utuH-1nozA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvd PYRUVATE
DECARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 THR A 266
GLU A 277
THR A 303
LEU A 289
 None
 1.23A 5utuH-1pvdA:
undetectable		 5utuH-1pvdA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9k PROBABLE
METHYLTHIORIBOSE-1-P
HOSPHATE ISOMERASE

(Thermotoga
maritima) 		PF01008
(IF-2B) 		4 THR A   7
GLU A 201
THR A 198
HIS A 153
 None
 1.33A 5utuH-1t9kA:
2.1		 5utuH-1t9kA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tht THIOESTERASE

(Vibrio harveyi) 		PF02273
(Acyl_transf_2) 		4 THR A 105
GLU A  24
HIS A  21
LEU A  12
 None
 1.05A 5utuH-1thtA:
6.5		 5utuH-1thtA:
20.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1v8b ADENOSYLHOMOCYSTEINA
SE

(Plasmodium
falciparum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 GLU A 200
THR A 201
HIS A 345
LEU A 389
 ADN  A 502 (-4.0A)
NAD  A 501 ( 2.8A)
NAD  A 501 (-4.8A)
NAD  A 501 ( 3.8A)
 0.37A 5utuH-1v8bA:
56.7		 5utuH-1v8bA:
52.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9p DNA LIGASE

(Thermus
filiformis) 		PF01653
(DNA_ligase_aden)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		4 THR A 224
GLU A 116
THR A 114
LEU A 245
 None
AMP  A 700 (-3.7A)
None
None
 1.30A 5utuH-1v9pA:
undetectable		 5utuH-1v9pA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpu IRON TRANSPORT
MULTICOPPER OXIDASE
FET3

(Saccharomyces
cerevisiae) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 THR A 122
GLU A 155
HIS A 262
LEU A 260
 None
BMA  A3001 (-4.2A)
None
None
 1.26A 5utuH-1zpuA:
undetectable		 5utuH-1zpuA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1w ENDOU PROTEIN

(Xenopus laevis) 		PF09412
(XendoU) 		4 THR A  76
GLU A 236
HIS A 119
LEU A 139
 None
 1.25A 5utuH-2c1wA:
undetectable		 5utuH-2c1wA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2czc GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF01113
(DapB_N)
PF02800
(Gp_dh_C) 		4 GLU A 205
THR A 206
HIS A 219
LEU A 150
 None
 1.33A 5utuH-2czcA:
5.6		 5utuH-2czcA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g1k SHIKIMATE KINASE

(Mycobacterium
tuberculosis) 		PF01202
(SKI) 		4 GLU A  61
THR A  33
HIS A  72
LEU A  69
 SKM  A 401 ( 4.7A)
None
None
None
 1.17A 5utuH-2g1kA:
undetectable		 5utuH-2g1kA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3b PUTATIVE TETR-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii) 		PF00440
(TetR_N)
PF13977
(TetR_C_6) 		4 THR A 121
GLU A  52
HIS A  43
LEU A   9
 None
 1.13A 5utuH-2g3bA:
undetectable		 5utuH-2g3bA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i9x PUTATIVE SEPTATION
PROTEIN SPOVG

(Staphylococcus
epidermidis) 		PF04026
(SpoVG) 		4 THR A   4
GLU A  71
HIS A  62
LEU A  34
 None
 1.20A 5utuH-2i9xA:
undetectable		 5utuH-2i9xA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ovi HYPOTHETICAL PROTEIN
CHUX

(Escherichia
coli) 		PF06228
(ChuX_HutX) 		4 THR A  40
GLU A 111
THR A 119
LEU A  18
 None
 1.28A 5utuH-2oviA:
undetectable		 5utuH-2oviA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qua EXTRACELLULAR LIPASE

(Serratia
marcescens) 		no annotation 4 THR A 524
GLU A 427
THR A 426
LEU A 435
 None
 0.84A 5utuH-2quaA:
3.2		 5utuH-2quaA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2var FRUCTOKINASE

(Sulfolobus
solfataricus) 		PF00294
(PfkB) 		4 THR A  87
THR A 138
HIS A 133
LEU A  52
 None
 1.28A 5utuH-2varA:
4.8		 5utuH-2varA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w3z PUTATIVE DEACETYLASE

(Streptococcus
mutans) 		PF01522
(Polysacc_deac_1) 		4 THR A 146
THR A 122
HIS A 161
LEU A 163
 None
 1.32A 5utuH-2w3zA:
2.5		 5utuH-2w3zA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xio PUTATIVE
DEOXYRIBONUCLEASE
TATDN1

(Homo sapiens) 		PF01026
(TatD_DNase) 		4 THR A 289
GLU A 220
THR A 221
HIS A 262
 None
 1.35A 5utuH-2xioA:
undetectable		 5utuH-2xioA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a1i AMIDASE

(Rhodococcus sp.
N-771) 		PF01425
(Amidase) 		4 THR A 424
THR A 234
HIS A 238
LEU A 491
 None
 1.08A 5utuH-3a1iA:
undetectable		 5utuH-3a1iA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5w PROBABLE
PEROXIREDOXIN

(Aeropyrum
pernix) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 THR A 108
THR A  19
HIS A  29
LEU A  26
 None
 1.08A 5utuH-3a5wA:
undetectable		 5utuH-3a5wA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aib GLUCOSYLTRANSFERASE-
SI

(Streptococcus
mutans) 		PF02324
(Glyco_hydro_70) 		4 THR A1067
THR A1078
HIS A 261
LEU A 266
 None
 1.34A 5utuH-3aibA:
undetectable		 5utuH-3aibA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8t FUMARATE LYASE

(Chelativorans
sp. BNC1) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 GLU A  45
THR A  46
HIS A 112
LEU A  96
 None
 1.24A 5utuH-3c8tA:
undetectable		 5utuH-3c8tA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d62 3C-LIKE PROTEINASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF05409
(Peptidase_C30) 		4 THR A 243
GLU A 240
THR A 199
LEU A 268
 None
 1.10A 5utuH-3d62A:
undetectable		 5utuH-3d62A:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g1u ADENOSYLHOMOCYSTEINA
SE

(Leishmania
major) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 THR A  57
GLU A 155
THR A 156
LEU A 343
 ADN  A 438 (-4.6A)
ADN  A 438 (-3.8A)
NAD  A 439 ( 3.0A)
NAD  A 439 ( 4.0A)
 0.64A 5utuH-3g1uA:
51.1		 5utuH-3g1uA:
50.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3glq ADENOSYLHOMOCYSTEINA
SE

(Burkholderia
pseudomallei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 THR A  67
GLU A 199
THR A 200
LEU A 385
 RAB  A 602 (-4.5A)
RAB  A 602 (-4.6A)
NAD  A 601 ( 2.9A)
NAD  A 601 ( 4.1A)
 0.74A 5utuH-3glqA:
55.9		 5utuH-3glqA:
50.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h9u ADENOSYLHOMOCYSTEINA
SE

(Trypanosoma
brucei) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 THR A  57
GLU A 155
THR A 156
LEU A 343
 ADN  A 439 (-4.7A)
None
NAD  A 438 (-3.8A)
NAD  A 438 (-4.0A)
 0.58A 5utuH-3h9uA:
53.5		 5utuH-3h9uA:
51.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmj FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00109
(ketoacyl-synt)
PF01648
(ACPS)
PF02801
(Ketoacyl-synt_C) 		4 THR A 610
GLU A 474
HIS A 454
LEU A 413
 None
 1.34A 5utuH-3hmjA:
2.6		 5utuH-3hmjA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hym CELL DIVISION CYCLE
PROTEIN 16 HOMOLOG

(Homo sapiens) 		PF13424
(TPR_12) 		4 THR B 254
GLU B 283
HIS B 289
LEU B 291
 None
 1.24A 5utuH-3hymB:
undetectable		 5utuH-3hymB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2n WD REPEAT-CONTAINING
PROTEIN 92

(Homo sapiens) 		PF00400
(WD40) 		4 GLU A 205
THR A 206
HIS A 237
LEU A 215
 None
 1.14A 5utuH-3i2nA:
undetectable		 5utuH-3i2nA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 THR A1215
GLU A1465
THR A1464
HIS A1484
 None
 1.01A 5utuH-3jb9A:
undetectable		 5utuH-3jb9A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8c RIBOSE 5-PHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF02502
(LacAB_rpiB) 		4 THR A   9
THR A 114
HIS A  91
LEU A  89
 None
 1.27A 5utuH-3k8cA:
3.4		 5utuH-3k8cA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8c RIBOSE 5-PHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF02502
(LacAB_rpiB) 		4 THR A   9
THR A 115
HIS A  91
LEU A  89
 None
 1.24A 5utuH-3k8cA:
3.4		 5utuH-3k8cA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpp SUCRASE-ISOMALTASE

(Homo sapiens) 		PF00088
(Trefoil)
PF01055
(Glyco_hydro_31)
PF16863
(NtCtMGAM_N) 		4 THR A 679
GLU A 687
HIS A 757
LEU A 707
 None
 1.29A 5utuH-3lppA:
undetectable		 5utuH-3lppA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m07 PUTATIVE ALPHA
AMYLASE

(Salmonella
enterica) 		PF00128
(Alpha-amylase)
PF11941
(DUF3459) 		4 THR A 502
GLU A 433
HIS A 119
LEU A 485
 None
 1.16A 5utuH-3m07A:
2.4		 5utuH-3m07A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1p RIBOSE 5-PHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF02502
(LacAB_rpiB) 		4 THR A   9
THR A 114
HIS A  91
LEU A  89
 None
 1.26A 5utuH-3m1pA:
2.7		 5utuH-3m1pA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1p RIBOSE 5-PHOSPHATE
ISOMERASE

(Trypanosoma
cruzi) 		PF02502
(LacAB_rpiB) 		4 THR A   9
THR A 115
HIS A  91
LEU A  89
 None
 1.22A 5utuH-3m1pA:
2.7		 5utuH-3m1pA:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m7m 33 KDA CHAPERONIN

(Escherichia
coli) 		PF01430
(HSP33) 		4 THR X 137
GLU X 143
THR X 154
LEU X  57
 None
 1.35A 5utuH-3m7mX:
undetectable		 5utuH-3m7mX:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0u PROBABLE
N-GLYCOSYLASE/DNA
LYASE

(Thermotoga
maritima) 		no annotation 4 THR A  48
GLU A  41
THR A 138
LEU A 119
 None
 1.03A 5utuH-3n0uA:
undetectable		 5utuH-3n0uA:
17.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3n58 ADENOSYLHOMOCYSTEINA
SE

(Brucella
abortus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 THR A  60
GLU A 192
THR A 193
LEU A 378
 ADN  A 500 (-4.6A)
ADN  A 500 (-3.6A)
NAD  A 550 ( 3.0A)
NAD  A 550 (-4.3A)
 0.54A 5utuH-3n58A:
27.4		 5utuH-3n58A:
52.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nrv PUTATIVE
TRANSCRIPTIONAL
REGULATOR (MARR/EMRR
FAMILY)

(Acinetobacter
sp. ADP1) 		PF12802
(MarR_2) 		4 THR A  30
GLU A  39
THR A  71
LEU A  61
 SO4  A 147 (-4.0A)
None
None
None
 1.26A 5utuH-3nrvA:
undetectable		 5utuH-3nrvA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nze PUTATIVE
TRANSCRIPTIONAL
REGULATOR,
SUGAR-BINDING FAMILY

(Paenarthrobacter
aurescens) 		PF04198
(Sugar-bind) 		4 THR A 185
GLU A 262
THR A 259
HIS A 230
 None
 1.22A 5utuH-3nzeA:
3.7		 5utuH-3nzeA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oev PROTEASOME COMPONENT
C1

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		4 THR F 165
GLU F 152
HIS F 123
LEU F  88
 MG  F 242 (-4.6A)
MG  F 242 ( 4.9A)
None
None
 1.21A 5utuH-3oevF:
undetectable		 5utuH-3oevF:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3one ADENOSYLHOMOCYSTEINA
SE

(Lupinus luteus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 THR A  67
GLU A 205
THR A 206
LEU A 395
 ADE  A 506 (-4.5A)
None
NAD  A 501 (-2.8A)
NAD  A 501 (-4.2A)
 0.38A 5utuH-3oneA:
55.7		 5utuH-3oneA:
55.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pl0 UNCHARACTERIZED
PROTEIN

(Methylibium
petroleiphilum) 		PF10014
(2OG-Fe_Oxy_2) 		4 THR A  33
THR A  13
HIS A   2
LEU A   7
 None
 1.25A 5utuH-3pl0A:
undetectable		 5utuH-3pl0A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swj PUTATIVE
UNCHARACTERIZED
PROTEIN

(Campylobacter
jejuni) 		PF01243
(Putative_PNPOx)
PF10615
(DUF2470) 		4 THR A 193
GLU A 188
THR A 122
LEU A 210
 None
 1.26A 5utuH-3swjA:
undetectable		 5utuH-3swjA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqx 2-AMINO-3-KETOBUTYRA
TE COENZYME A LIGASE

(Coxiella
burnetii) 		PF00155
(Aminotran_1_2) 		4 THR A 274
GLU A  91
THR A 103
LEU A 240
 None
 1.30A 5utuH-3tqxA:
2.4		 5utuH-3tqxA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ve2 TRANSFERRIN-BINDING
PROTEIN 2

(Neisseria
meningitidis) 		PF01298
(TbpB_B_D)
PF17483
(TbpB_C)
PF17484
(TbpB_A) 		4 THR A 475
GLU A 521
THR A 388
LEU A 397
 None
 1.27A 5utuH-3ve2A:
undetectable		 5utuH-3ve2A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4asc KELCH REPEAT AND BTB
DOMAIN-CONTAINING
PROTEIN 5

(Homo sapiens) 		PF01344
(Kelch_1) 		4 THR A 524
GLU A 528
HIS A 508
LEU A 552
 None
 1.25A 5utuH-4ascA:
undetectable		 5utuH-4ascA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbw SIALIDASE
(NEURAMINIDASE)

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2)
PF14873
(BNR_assoc_N) 		4 THR A 359
GLU A 404
THR A 405
HIS A 437
 None
 1.23A 5utuH-4bbwA:
undetectable		 5utuH-4bbwA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bhd SERINE
HYDROXYMETHYLTRANSFE
RASE

(Methanocaldococcus
jannaschii) 		PF00464
(SHMT) 		4 THR A 238
GLU A 104
THR A 105
LEU A 167
 None
 1.18A 5utuH-4bhdA:
undetectable		 5utuH-4bhdA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Neurospora
crassa) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		4 THR A 567
GLU A 539
HIS A 513
LEU A 509
 None
 1.18A 5utuH-4czwA:
undetectable		 5utuH-4czwA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f21 CARBOXYLESTERASE/PHO
SPHOLIPASE FAMILY
PROTEIN

(Francisella
tularensis) 		PF02230
(Abhydrolase_2) 		4 THR A 219
GLU A 193
HIS A 166
LEU A 139
 None
 1.32A 5utuH-4f21A:
2.6		 5utuH-4f21A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9i HYDROGENASE
MATURATION PROTEIN
HYPF

(Thermococcus
kodakarensis) 		PF00708
(Acylphosphatase)
PF00814
(Peptidase_M22)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 THR A 766
THR A 515
HIS A 487
LEU A 525
 None
 1.33A 5utuH-4g9iA:
undetectable		 5utuH-4g9iA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4id9 SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE

(Agrobacterium
fabrum) 		PF01370
(Epimerase) 		4 THR A 289
GLU A 122
THR A 249
LEU A 126
 None
 0.83A 5utuH-4id9A:
7.5		 5utuH-4id9A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iu6 METHIONINE
AMINOPEPTIDASE 1

(Homo sapiens) 		PF00557
(Peptidase_M24) 		4 THR A 244
THR A 172
HIS A  99
LEU A  96
 None
None
SO4  A 406 (-4.1A)
SO4  A 406 (-4.6A)
 1.30A 5utuH-4iu6A:
undetectable		 5utuH-4iu6A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg4 SERINE/THREONINE-PRO
TEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		4 THR A 210
THR A 125
HIS A 159
LEU A 154
 None
 1.34A 5utuH-4lg4A:
undetectable		 5utuH-4lg4A:
22.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lvc S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE)

(Bradyrhizobium
elkanii) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 THR A  63
GLU A 197
THR A 198
LEU A 383
 ADN  A 501 (-4.5A)
ADN  A 501 (-3.6A)
NAD  A 503 ( 2.9A)
NAD  A 503 ( 3.9A)
 0.26A 5utuH-4lvcA:
55.3		 5utuH-4lvcA:
51.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nzk UNCHARACTERIZED
PROTEIN

([Eubacterium]
siraeum) 		PF14286
(DHHW) 		4 THR A 226
GLU A 197
HIS A 183
LEU A 219
 None
 1.20A 5utuH-4nzkA:
2.1		 5utuH-4nzkA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4puc SUSD HOMOLOG

(Bacteroides
uniformis) 		PF12741
(SusD-like) 		4 THR A 364
GLU A 242
HIS A 247
LEU A 251
 None
 0.96A 5utuH-4pucA:
undetectable		 5utuH-4pucA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pws PROLINE-RICH 28 KDA
ANTIGEN

(Mycobacterium
tuberculosis) 		PF10738
(Lpp-LpqN) 		4 THR A 261
GLU A 215
THR A 199
LEU A 251
 None
 1.34A 5utuH-4pwsA:
undetectable		 5utuH-4pwsA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upk PHOSPHONATE
MONOESTER HYDROLASE

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase) 		4 THR A  76
GLU A 410
THR A 415
LEU A 406
 None
 1.12A 5utuH-4upkA:
undetectable		 5utuH-4upkA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x6k ANHYDROSIALIDASE

([Ruminococcus]
gnavus) 		PF13088
(BNR_2) 		4 THR A 305
GLU A 482
HIS A 349
LEU A 264
 None
 1.22A 5utuH-4x6kA:
undetectable		 5utuH-4x6kA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zsb HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR DASR

(Streptomyces
coelicolor) 		PF07702
(UTRA) 		4 THR A  99
GLU A 154
THR A 156
LEU A 188
 None
 1.19A 5utuH-4zsbA:
undetectable		 5utuH-4zsbA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bqs 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Streptococcus
pneumoniae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 THR A  90
GLU A 140
THR A 280
HIS A  44
 None
 1.26A 5utuH-5bqsA:
undetectable		 5utuH-5bqsA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzx PROTOCADHERIN BETA 6

(Mus musculus) 		PF00028
(Cadherin)
PF08266
(Cadherin_2) 		4 GLU A  52
THR A  53
HIS A  19
LEU A  57
 None
 1.23A 5utuH-5dzxA:
undetectable		 5utuH-5dzxA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e84 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		4 THR A 508
GLU A 498
THR A 445
LEU A 424
 None
 1.35A 5utuH-5e84A:
2.0		 5utuH-5e84A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es9 LINEAR GRAMICIDIN
SYNTHETASE SUBUNIT A

(Brevibacillus
parabrevis) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00551
(Formyl_trans_N)
PF13193
(AMP-binding_C) 		4 GLU A 601
THR A 613
HIS A 607
LEU A 646
 None
 1.09A 5utuH-5es9A:
3.5		 5utuH-5es9A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g5g PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT

(Escherichia
coli) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 THR C 720
GLU C 660
HIS C 654
LEU C 642
 None
GOL  B1323 (-4.5A)
None
None
 1.12A 5utuH-5g5gC:
undetectable		 5utuH-5g5gC:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gjn LYSINE/ORNITHINE
DECARBOXYLASE

(Selenomonas
ruminantium) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 THR A 353
GLU A 287
THR A 269
LEU A 305
 None
 1.23A 5utuH-5gjnA:
undetectable		 5utuH-5gjnA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h80 CARBOXYLASE

(Deinococcus
radiodurans) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 GLU A 299
THR A 298
HIS A 221
LEU A 324
 EDO  A 505 ( 4.2A)
None
None
None
 1.33A 5utuH-5h80A:
2.4		 5utuH-5h80A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ict GLUTAMATE RECEPTOR 1

(Drosophila
melanogaster) 		PF10613
(Lig_chan-Glu_bd) 		4 THR A  99
GLU A 151
HIS A 177
LEU A 144
 None
None
None
GLU  A 301 ( 3.8A)
 1.33A 5utuH-5ictA:
undetectable		 5utuH-5ictA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jri PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 4 THR A 277
THR A 131
HIS A 260
LEU A 262
 None
FAD  A 401 (-4.0A)
FAD  A 401 ( 4.5A)
None
 1.31A 5utuH-5jriA:
3.4		 5utuH-5jriA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3h ACYL-COENZYME A
OXIDASE

(Caenorhabditis
elegans) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		4 THR A 180
GLU A 153
THR A 152
LEU A 193
 None
 1.14A 5utuH-5k3hA:
undetectable		 5utuH-5k3hA:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kck ANTHRANILATE
SYNTHASE COMPONENT I

(Streptococcus
pneumoniae) 		PF00425
(Chorismate_bind)
PF04715
(Anth_synt_I_N) 		4 THR A 359
THR A 351
HIS A  77
LEU A 395
 None
 1.27A 5utuH-5kckA:
undetectable		 5utuH-5kckA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msc CARBOXYLIC ACID
REDUCTASE

(Nocardia
iowensis) 		PF00501
(AMP-binding) 		4 THR A 261
GLU A 160
THR A 161
LEU A 145
 None
 1.30A 5utuH-5mscA:
undetectable		 5utuH-5mscA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mux 2-METHYLCITRATE
DEHYDRATASE

(Bacillus
subtilis) 		no annotation 4 GLU A 290
THR A 287
HIS A 284
LEU A 274
 None
 1.34A 5utuH-5muxA:
undetectable		 5utuH-5muxA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		4 THR A3704
GLU A3575
THR A3550
LEU A3567
 None
 1.27A 5utuH-5nugA:
undetectable		 5utuH-5nugA:
7.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oy0 PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2

(Synechocystis
sp. PCC 6803) 		no annotation 4 THR b 502
GLU b 266
THR b 265
HIS b 242
 None
 1.31A 5utuH-5oy0b:
undetectable		 5utuH-5oy0b:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t5w INTERFERON LAMBDA
RECEPTOR 1

(Homo sapiens) 		PF01108
(Tissue_fac) 		4 THR B 156
THR B 151
HIS B 174
LEU B 176
 None
 1.22A 5utuH-5t5wB:
undetectable		 5utuH-5t5wB:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1d ANTIGEN PEPTIDE
TRANSPORTER 2
TAP TRANSPORTER
INHIBITOR ICP47

(Homo sapiens;
Human
alphaherpesvirus
1) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF05363
(Herpes_US12) 		4 THR X  21
GLU B 307
THR B 303
HIS B 299
 None
 1.07A 5utuH-5u1dX:
undetectable		 5utuH-5u1dX:
11.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5v96 S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE

(Naegleria
fowleri) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		5 THR A  64
GLU A 197
THR A 198
HIS A 342
LEU A 386
 ADN  A 502 (-4.4A)
ADN  A 502 (-3.5A)
NAD  A 501 ( 2.9A)
NAD  A 501 ( 4.9A)
NAD  A 501 (-3.9A)
 0.38A 5utuH-5v96A:
56.7		 5utuH-5v96A:
54.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vni PROTEIN TRANSPORT
PROTEIN SEC23A

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 THR A 652
THR A 708
HIS A 710
LEU A 719
 None
 1.20A 5utuH-5vniA:
undetectable		 5utuH-5vniA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y7o UGGT

(Thermomyces
dupontii) 		PF06427
(UDP-g_GGTase) 		4 THR A 314
THR A 903
HIS A 899
LEU A 304
 None
 1.30A 5utuH-5y7oA:
undetectable		 5utuH-5y7oA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus) 		no annotation 4 THR A 512
GLU A 502
THR A 445
LEU A 424
 None
 1.31A 5utuH-6eoeA:
2.4		 5utuH-6eoeA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f3m -

(-) 		no annotation 4 THR B  66
GLU B 164
THR B 165
LEU B 373
 ADN  B 502 (-4.6A)
ADN  B 502 (-3.6A)
NAD  B 501 ( 2.8A)
NAD  B 501 ( 3.9A)
 0.29A 5utuH-6f3mB:
50.0		 5utuH-6f3mB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g1o -

(-) 		no annotation 4 THR A 451
GLU A 352
THR A 353
HIS A 357
 None
 1.29A 5utuH-6g1oA:
2.1		 5utuH-6g1oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gbn -

(-) 		no annotation 4 THR A  61
GLU A 159
THR A 160
LEU A 347
 ADN  A 501 (-4.6A)
ADN  A 501 (-3.9A)
NAD  A 502 ( 2.8A)
NAD  A 502 (-3.9A)
 0.28A 5utuH-6gbnA:
25.9		 5utuH-6gbnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gdr -

(-) 		no annotation 4 THR A 183
GLU A  33
HIS A 193
LEU A 192
 None
 1.32A 5utuH-6gdrA:
undetectable		 5utuH-6gdrA:
undetectable