SIMILAR PATTERNS OF AMINO ACIDS FOR 5UIZ_A_CUA301

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iq0 ARGINYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		4 HIS A 481
ALA A 588
HIS A 477
GLN A 574
 None
 1.39A 5uizA-1iq0A:
undetectable		 5uizA-1iq0A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itx GLYCOSYL HYDROLASE

(Bacillus
circulans) 		PF00704
(Glyco_hydro_18) 		4 HIS A 291
ALA A 393
GLN A 352
TYR A 353
 None
 1.21A 5uizA-1itxA:
undetectable		 5uizA-1itxA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jc4 METHYLMALONYL-COA
EPIMERASE

(Propionibacterium
freudenreichii) 		PF13669
(Glyoxalase_4) 		4 HIS A  91
ALA A  93
HIS A  12
GLN A  65
 None
None
SO4  A 203 ( 4.8A)
SO4  A 203 (-2.6A)
 0.96A 5uizA-1jc4A:
undetectable		 5uizA-1jc4A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kkc MANGANESE SUPEROXIDE
DISMUTASE

(Aspergillus
fumigatus) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 HIS A  88
HIS A 178
GLN A 161
TYR A  48
 MN  A2001 (-3.4A)
MN  A2001 (-3.4A)
MN  A2001 ( 4.8A)
None
 1.30A 5uizA-1kkcA:
undetectable		 5uizA-1kkcA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tg6 PUTATIVE
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT

(Homo sapiens) 		PF00574
(CLP_protease) 		4 HIS A 156
ALA A 104
GLN A  81
TYR A  77
 None
 1.26A 5uizA-1tg6A:
undetectable		 5uizA-1tg6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a3l AMP DEAMINASE

(Arabidopsis
thaliana) 		PF00962
(A_deaminase) 		4 HIS A 393
ALA A 396
GLN A 546
TYR A 467
 ZN  A 840 ( 3.2A)
CF5  A 841 ( 4.7A)
None
CF5  A 841 (-2.7A)
 1.31A 5uizA-2a3lA:
undetectable		 5uizA-2a3lA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a7s PROBABLE
PROPIONYL-COA
CARBOXYLASE BETA
CHAIN 5

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		4 HIS A 195
ALA A 153
GLN A 115
TYR A 128
 None
 1.34A 5uizA-2a7sA:
undetectable		 5uizA-2a7sA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7z ACETYLENE HYDRATASE
AHY

(Pelobacter
acetylenicus) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 HIS A 343
ALA A 389
HIS A 385
GLN A 341
 None
 1.49A 5uizA-2e7zA:
undetectable		 5uizA-2e7zA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4p HYPOTHETICAL PROTEIN
TM1010

(Thermotoga
maritima) 		PF07883
(Cupin_2) 		4 HIS A  52
ALA A 117
HIS A  54
GLN A  58
 UNL  A 136 (-3.3A)
UNL  A 136 ( 4.9A)
UNL  A 136 (-3.7A)
UNL  A 136 (-3.2A)
 0.97A 5uizA-2f4pA:
undetectable		 5uizA-2f4pA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqt UDP-N-ACETYLENOLPYRU
VYLGLUCOSAMINE
REDUCTASE

(Thermus
caldophilus) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		4 HIS A 134
ALA A 137
HIS A 139
TYR A 141
 None
 1.20A 5uizA-2gqtA:
undetectable		 5uizA-2gqtA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ogs THERMOSTABLE
CARBOXYLESTERASE
EST50

(Geobacillus
stearothermophilus) 		PF00135
(COesterase) 		4 HIS A 418
ALA A 124
HIS A 128
TYR A 444
 HIS  A 418 ( 1.0A)
ALA  A 124 ( 0.0A)
HIS  A 128 ( 1.0A)
TYR  A 444 ( 1.3A)
 0.94A 5uizA-2ogsA:
undetectable		 5uizA-2ogsA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpx PREDICTED
METAL-DEPENDENT
HYDROLASE OF THE
TIM-BARREL FOLD

(Lactobacillus
paracasei) 		PF04909
(Amidohydro_2) 		4 HIS A  17
ALA A 315
HIS A  16
GLN A 225
 ZN  A 376 (-3.3A)
None
None
KCX  A 166 ( 4.9A)
 1.10A 5uizA-2qpxA:
undetectable		 5uizA-2qpxA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vtc CEL61B

(Trichoderma
reesei) 		PF03443
(Glyco_hydro_61) 		4 HIS A   1
HIS A  89
GLN A 174
TYR A 176
 NI  A1231 (-3.2A)
NI  A1231 (-3.2A)
NI  A1231 ( 4.7A)
NI  A1231 (-4.7A)
 0.78A 5uizA-2vtcA:
8.5		 5uizA-2vtcA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9n ALKANE MONOOXYGENASE

(Geobacillus
thermodenitrificans) 		PF00296
(Bac_luciferase) 		4 HIS A 311
HIS A  20
GLN A  79
TYR A  63
 None
 1.35A 5uizA-3b9nA:
undetectable		 5uizA-3b9nA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans) 		PF03713
(DUF305) 		4 HIS A  44
ALA A  47
HIS A 134
GLN A 165
 None
 1.47A 5uizA-3bt5A:
undetectable		 5uizA-3bt5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e23 UNCHARACTERIZED
PROTEIN RPA2492

(Rhodopseudomonas
palustris) 		PF08241
(Methyltransf_11) 		4 HIS A 196
ALA A 110
HIS A 109
TYR A 138
 SO4  A 223 (-4.4A)
SAM  A 221 (-4.3A)
SAM  A 221 ( 3.7A)
None
 1.17A 5uizA-3e23A:
undetectable		 5uizA-3e23A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e61 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR OF RIBOSE
OPERON

(Staphylococcus
saprophyticus) 		PF13377
(Peripla_BP_3) 		4 ALA A 187
HIS A 157
GLN A 281
TYR A 263
 GOL  A   1 ( 4.1A)
GOL  A   1 ( 4.7A)
GOL  A   1 (-3.3A)
None
 1.19A 5uizA-3e61A:
undetectable		 5uizA-3e61A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egl DEGV FAMILY PROTEIN

(Corynebacterium
glutamicum) 		PF02645
(DegV) 		4 HIS A 141
ALA A 214
GLN A 185
TYR A 139
 None
 1.18A 5uizA-3eglA:
undetectable		 5uizA-3eglA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eja PROTEIN GH61E

(Thielavia
terrestris) 		PF03443
(Glyco_hydro_61) 		4 HIS A   1
HIS A  68
GLN A 151
TYR A 153
 MG  A 701 (-3.2A)
MG  A 701 (-3.3A)
SO4  A4851 (-3.2A)
None
 0.76A 5uizA-3ejaA:
8.5		 5uizA-3ejaA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN

(Wolbachia
endosymbiont of
Drosophila
melanogaster) 		PF13462
(Thioredoxin_4) 		4 HIS A  96
ALA A  92
HIS A  81
TYR A 104
 None
 1.14A 5uizA-3f4sA:
undetectable		 5uizA-3f4sA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iuz PUTATIVE GLYOXALASE
SUPERFAMILY PROTEIN

(Cupriavidus
pinatubonensis) 		PF07063
(DUF1338) 		4 HIS A  81
ALA A  83
HIS A 237
GLN A 273
 None
 1.37A 5uizA-3iuzA:
undetectable		 5uizA-3iuzA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iwz CATABOLITE
ACTIVATION-LIKE
PROTEIN

(Xanthomonas
campestris) 		PF00027
(cNMP_binding)
PF00325
(Crp) 		4 HIS A 218
HIS A 180
GLN A 182
TYR A 227
 None
 1.24A 5uizA-3iwzA:
undetectable		 5uizA-3iwzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n0t DIPEPTIDYL PEPTIDASE
2

(Homo sapiens) 		PF05577
(Peptidase_S28) 		4 ALA A 134
HIS A 107
GLN A 350
TYR A 163
 None
 1.41A 5uizA-3n0tA:
undetectable		 5uizA-3n0tA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujh GLUCOSE-6-PHOSPHATE
ISOMERASE

(Toxoplasma
gondii) 		PF00342
(PGI) 		4 HIS A 142
ALA A 245
HIS A 246
TYR A 236
 None
 1.44A 5uizA-3ujhA:
undetectable		 5uizA-3ujhA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vnk XYLOSE ISOMERASE
DOMAIN PROTEIN TIM
BARREL

([Clostridium]
cellulolyticum) 		PF01261
(AP_endonuc_2) 		4 ALA A  37
HIS A  66
GLN A  72
TYR A  89
 None
 1.45A 5uizA-3vnkA:
undetectable		 5uizA-3vnkA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b5q GLYCOSIDE HYDROLASE
FAMILY 61 PROTEIN D

(Phanerochaete
chrysosporium) 		PF03443
(Glyco_hydro_61) 		4 HIS A   1
HIS A  76
GLN A 158
TYR A 160
 CU  A 221 ( 3.0A)
CU  A 221 ( 3.1A)
GOL  A 222 (-3.0A)
CU  A 221 (-4.9A)
 0.73A 5uizA-4b5qA:
8.4		 5uizA-4b5qA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c7u SUPEROXIDE DISMUTASE
[MN] 1,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 HIS A  74
HIS A 167
GLN A 146
TYR A  34
 MN  A 302 (-3.4A)
MN  A 302 (-3.4A)
MN  A 302 ( 4.7A)
None
 1.31A 5uizA-4c7uA:
undetectable		 5uizA-4c7uA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7u ENDOGLUCANASE II

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		5 HIS A   1
ALA A  80
HIS A  83
GLN A 164
TYR A 166
 CU  A 300 (-3.0A)
None
CU  A 300 (-3.1A)
CU  A 300 (-4.3A)
None
 0.80A 5uizA-4d7uA:
7.9		 5uizA-4d7uA:
20.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4gbo E7

(Thermobifida
fusca) 		PF03067
(LPMO_10) 		5 HIS A  37
ALA A 142
HIS A 144
GLN A 211
TYR A 213
 CU  A 301 (-2.9A)
CU  A 301 ( 3.9A)
CU  A 301 (-3.4A)
CU  A 301 ( 4.7A)
None
 0.06A 5uizA-4gboA:
39.1		 5uizA-4gboA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mah AA11 LYTIC
POLYSACCHARIDE
MONOOXYGENASE

(Aspergillus
oryzae) 		no annotation 4 HIS A   1
ALA A  58
HIS A  60
TYR A 140
 ZN  A 301 (-3.1A)
ZN  A 301 ( 3.9A)
ZN  A 301 (-3.2A)
None
 0.56A 5uizA-4mahA:
9.3		 5uizA-4mahA:
23.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4oy8 PUTATIVE SECRETED
CELLULOSE-BINDING
PROTEIN

(Streptomyces
coelicolor) 		PF03067
(LPMO_10) 		5 HIS A  43
ALA A 148
HIS A 150
GLN A 217
TYR A 219
 ZN  A 305 ( 3.1A)
ACT  A 311 ( 3.1A)
ZN  A 305 ( 3.2A)
None
None
 0.58A 5uizA-4oy8A:
35.5		 5uizA-4oy8A:
69.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4oy8 PUTATIVE SECRETED
CELLULOSE-BINDING
PROTEIN

(Streptomyces
coelicolor) 		PF03067
(LPMO_10) 		4 HIS A  43
HIS A 214
GLN A 217
TYR A 219
 ZN  A 305 ( 3.1A)
None
None
None
 1.10A 5uizA-4oy8A:
35.5		 5uizA-4oy8A:
69.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qi8 LYTIC POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		4 HIS A   1
HIS A  72
GLN A 155
TYR A 157
 CU  A 301 ( 3.1A)
CU  A 301 (-3.2A)
CU  A 301 ( 4.6A)
CU  A 301 (-4.8A)
 0.80A 5uizA-4qi8A:
8.4		 5uizA-4qi8A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rk2 PUTATIVE SUGAR ABC
TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Rhizobium etli) 		PF01547
(SBP_bac_1) 		4 HIS A 399
ALA A 398
GLN A 204
TYR A 227
 None
 1.29A 5uizA-4rk2A:
undetectable		 5uizA-4rk2A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv7 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR

(Bacillus
subtilis) 		PF00155
(Aminotran_1_2)
PF00392
(GntR) 		4 HIS A 400
ALA A 397
HIS A 248
TYR A 281
 None
None
None
LLP  A 312 ( 4.0A)
 1.38A 5uizA-4tv7A:
undetectable		 5uizA-4tv7A:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0g ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2

(Mycobacterium
tuberculosis) 		PF00574
(CLP_protease) 		4 HIS A 171
ALA A 117
GLN A  94
TYR A  90
 None
 1.21A 5uizA-4u0gA:
undetectable		 5uizA-4u0gA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5foh POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		4 HIS A   1
HIS A  81
GLN A 162
TYR A 164
 CU  A1226 ( 3.0A)
CU  A1226 ( 3.3A)
SO4  A1227 ( 3.3A)
None
 0.62A 5uizA-5fohA:
8.6		 5uizA-5fohA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5it9 RIBOSOMAL PROTEIN
US15

(Kluyveromyces
lactis) 		PF00312
(Ribosomal_S15)
PF08069
(Ribosomal_S13_N) 		4 ALA N  57
HIS N  58
GLN N  36
TYR N  40
 None
 1.04A 5uizA-5it9N:
undetectable		 5uizA-5it9N:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msz THERMOBIA DOMESTICA
DOMESTICA AA15

(Thermobia
domestica) 		no annotation 4 HIS A   1
ALA A  89
HIS A  91
TYR A 184
 CU1  A 303 (-3.0A)
CU1  A 303 ( 4.0A)
CU1  A 303 (-3.2A)
CU1  A 303 (-4.9A)
 0.65A 5uizA-5mszA:
14.1		 5uizA-5mszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n05 AUXILIARY ACTIVITY 9

(Lentinus
similis) 		PF03443
(Glyco_hydro_61) 		4 ALA A  75
HIS A  78
GLN A 162
TYR A 164
 BGC  A 305 (-3.6A)
CU  A 301 ( 3.2A)
CL  A 309 (-3.3A)
HIC  A   1 (-3.9A)
 0.73A 5uizA-5n05A:
7.8		 5uizA-5n05A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nns GLYCOSYL HYDROLASE
FAMILY 61, 2 PROTEIN

(Heterobasidion
irregulare) 		no annotation 4 HIS A   1
HIS A  80
GLN A 165
TYR A 167
 CU  A 303 (-3.2A)
CU  A 303 ( 3.3A)
GOL  A 309 (-3.3A)
None
 0.56A 5uizA-5nnsA:
8.1		 5uizA-5nnsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5no7 LYTIC POLYSACCHARIDE
MONOOXYGENASE

(Trametes
cinnabarina) 		no annotation 4 HIS A   1
HIS A  99
GLN A 174
TYR A 176
 None
 0.70A 5uizA-5no7A:
6.6		 5uizA-5no7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opf CHITIN-BINDING
DOMAIN 3 PROTEIN

(Micromonospora
aurantiaca) 		no annotation 5 HIS A  37
ALA A 142
HIS A 144
GLN A 219
TYR A 221
 CU  A 301 (-3.0A)
CU  A 301 ( 3.9A)
CU  A 301 (-3.2A)
CU  A 301 ( 4.2A)
None
 0.24A 5uizA-5opfA:
34.4		 5uizA-5opfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tkf LYTIC POLYSACCHARIDE
MONOOXYGENASE

(Neurospora
crassa) 		PF03443
(Glyco_hydro_61) 		4 HIS A   1
HIS A  84
GLN A 166
TYR A 168
 CU  A 308 (-3.0A)
CU  A 308 (-3.1A)
CU  A 308 (-4.2A)
CU  A 308 (-4.9A)
 0.64A 5uizA-5tkfA:
8.4		 5uizA-5tkfA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wtk CRISPR-ASSOCIATED
ENDORIBONUCLEASE
C2C2

(Leptotrichia
shahii) 		no annotation 4 HIS A 602
ALA A 603
HIS A 492
TYR A1241
 None
 1.16A 5uizA-5wtkA:
undetectable		 5uizA-5wtkA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zrz STERILE ALPHA MOTIF
DOMAIN-CONTAINING
PROTEIN 5

(Mus musculus) 		no annotation 4 ALA B  48
HIS B  51
GLN B  17
TYR B  18
 None
 1.15A 5uizA-5zrzB:
undetectable		 5uizA-5zrzB:
undetectable