SIMILAR PATTERNS OF AMINO ACIDS FOR 5TUD_D_ERMD1201_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6d THERMOSOME (ALPHA
SUBUNIT)

(Thermoplasma
acidophilum) 		PF00118
(Cpn60_TCP1) 		4 LEU A 502
VAL A 506
THR A 510
GLU A 442
 None
 0.90A 5tudD-1a6dA:
0.0		 5tudD-1a6dA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1al8 GLYCOLATE OXIDASE

(Spinacia
oleracea) 		PF01070
(FMN_dh) 		4 LEU A  65
THR A 101
LEU A 228
GLU A 145
 None
 0.91A 5tudD-1al8A:
0.0		 5tudD-1al8A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1au1 INTERFERON-BETA

(Homo sapiens) 		PF00143
(Interferon) 		4 LEU A 106
VAL A 101
LEU A 160
GLU A  61
 None
 0.92A 5tudD-1au1A:
2.7		 5tudD-1au1A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aw9 GLUTATHIONE
S-TRANSFERASE III

(Zea mays) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A  11
VAL A  16
THR A  20
LEU A 213
 None
 0.98A 5tudD-1aw9A:
undetectable		 5tudD-1aw9A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxy D-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Lactobacillus
casei) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 LEU A 312
VAL A 316
THR A 320
GLU A  28
 None
 0.97A 5tudD-1dxyA:
0.0		 5tudD-1dxyA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ey1 ANTITERMINATION
FACTOR NUSB

(Escherichia
coli) 		PF01029
(NusB) 		4 LEU A  51
VAL A  55
THR A  59
LEU A 110
 None
 0.90A 5tudD-1ey1A:
0.7		 5tudD-1ey1A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		4 LEU A 170
VAL A 177
THR A 282
LEU A 204
 None
 0.99A 5tudD-1f1xA:
0.0		 5tudD-1f1xA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fbt FRUCTOSE-2,6-BISPHOS
PHATASE

(Rattus
norvegicus) 		PF00300
(His_Phos_1) 		5 LEU A  48
VAL A  67
LEU A 138
LEU A  75
GLU A 130
 None
 1.34A 5tudD-1fbtA:
undetectable		 5tudD-1fbtA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fng PROTEIN (MHC CLASS
II I-EK, BETA CHAIN)

(Mus musculus) 		PF00969
(MHC_II_beta)
PF07654
(C1-set) 		4 LEU B 161
VAL B 159
THR B 157
GLU B 187
 None
 0.80A 5tudD-1fngB:
undetectable		 5tudD-1fngB:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gk2 HISTIDINE
AMMONIA-LYASE

(Pseudomonas
putida) 		PF00221
(Lyase_aromatic) 		4 LEU A 438
VAL A 489
LEU A 427
GLU A 212
 None
 0.96A 5tudD-1gk2A:
0.0		 5tudD-1gk2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		4 VAL B 628
THR B 630
LEU B 532
GLU B 539
 None
 0.92A 5tudD-1gl9B:
0.1		 5tudD-1gl9B:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqj ALPHA-D-GLUCURONIDAS
E

(Cellvibrio
japonicus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		4 LEU A 103
VAL A 114
LEU A 134
GLU A  48
 None
 0.90A 5tudD-1gqjA:
2.2		 5tudD-1gqjA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j7g D-TYROSYL-TRNA(TYR)
DEACYLASE

(Haemophilus
influenzae) 		PF02580
(Tyr_Deacylase) 		5 LEU A 117
VAL A 119
THR A 121
LEU A  50
LEU A 142
 None
 1.12A 5tudD-1j7gA:
undetectable		 5tudD-1j7gA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jf0 OBELIN

(Obelia
longissima) 		PF13499
(EF-hand_7)
PF13833
(EF-hand_8) 		4 VAL A   7
LEU A 100
LEU A 110
GLU A 107
 None
 0.98A 5tudD-1jf0A:
undetectable		 5tudD-1jf0A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jn0 GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
A

(Spinacia
oleracea) 		no annotation 4 LEU O 267
VAL O 288
THR O 286
LEU O 242
 None
 0.96A 5tudD-1jn0O:
undetectable		 5tudD-1jn0O:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jr7 HYPOTHETICAL 37.4
KDA PROTEIN IN
ILEY-GABD INTERGENIC
REGION

(Escherichia
coli) 		PF08943
(CsiD) 		4 LEU A 283
VAL A 173
LEU A 190
GLU A  92
 None
 0.99A 5tudD-1jr7A:
undetectable		 5tudD-1jr7A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5s PENICILLIN G ACYLASE
BETA SUBUNIT

(Escherichia
coli) 		PF01804
(Penicil_amidase) 		5 LEU B 310
VAL B 320
THR B 324
LEU B 424
GLU B 432
 None
 1.43A 5tudD-1k5sB:
undetectable		 5tudD-1k5sB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k6m 6-PHOSPHOFRUCTO-2-KI
NASE/FRUCTOSE-2,6-BI
PHOSPHATASE
2-PHOSPHATASE

(Homo sapiens) 		PF00300
(His_Phos_1)
PF01591
(6PF2K) 		5 LEU A 298
VAL A 317
LEU A 388
LEU A 325
GLU A 380
 None
 1.31A 5tudD-1k6mA:
undetectable		 5tudD-1k6mA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9a CARBOXYL-TERMINAL
SRC KINASE

(Rattus
norvegicus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		4 LEU A 149
VAL A 153
THR A 157
LEU A  95
 None
 0.90A 5tudD-1k9aA:
3.9		 5tudD-1k9aA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l4i SFAE PROTEIN

(Escherichia
coli) 		PF00345
(PapD_N)
PF02753
(PapD_C) 		4 LEU A  20
VAL A  18
LEU A  82
GLU A  38
 None
 0.85A 5tudD-1l4iA:
undetectable		 5tudD-1l4iA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis) 		PF01018
(GTP1_OBG)
PF01926
(MMR_HSR1) 		4 VAL A 280
LEU A 163
LEU A 272
GLU A 264
 None
 0.97A 5tudD-1lnzA:
undetectable		 5tudD-1lnzA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m39 CALTRACTIN, ISOFORM
1

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 LEU A 163
LEU A 107
LEU A 112
GLU A 117
 None
 0.98A 5tudD-1m39A:
undetectable		 5tudD-1m39A:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlu SEDOLISIN

(Pseudomonas sp.) 		no annotation 4 LEU A  54
VAL A  57
THR A  59
LEU A 296
 None
 0.92A 5tudD-1nluA:
undetectable		 5tudD-1nluA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oxj RNA-BINDING PROTEIN
SMAUG

(Drosophila
melanogaster) 		PF00536
(SAM_1)
PF09246
(PHAT) 		4 LEU A 674
VAL A 678
THR A 682
LEU A 717
 None
 0.85A 5tudD-1oxjA:
undetectable		 5tudD-1oxjA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p27 MAGO NASHI PROTEIN
HOMOLOG

(Homo sapiens) 		PF02792
(Mago_nashi) 		4 LEU A 129
VAL A 133
LEU A   7
GLU A  58
 None
 0.73A 5tudD-1p27A:
undetectable		 5tudD-1p27A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qun PAPD-LIKE CHAPERONE
FIMC

(Escherichia
coli) 		PF00345
(PapD_N)
PF02753
(PapD_C) 		4 LEU A  20
VAL A  18
LEU A  82
GLU A  38
 None
 0.60A 5tudD-1qunA:
undetectable		 5tudD-1qunA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qzz ACLACINOMYCIN-10-HYD
ROXYLASE

(Streptomyces
purpurascens) 		PF00891
(Methyltransf_2) 		4 LEU A  33
LEU A  98
LEU A  46
GLU A  80
 None
 0.85A 5tudD-1qzzA:
undetectable		 5tudD-1qzzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rtr GERANYLTRANSTRANSFER
ASE

(Staphylococcus
aureus) 		PF00348
(polyprenyl_synt) 		4 LEU A  50
LEU A  71
LEU A  38
GLU A  16
 None
 0.93A 5tudD-1rtrA:
2.2		 5tudD-1rtrA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw0 CONSERVED
HYPOTHETICAL PROTEIN

(Salmonella
enterica) 		PF02578
(Cu-oxidase_4) 		4 LEU A  34
THR A 104
LEU A  54
GLU A  48
 None
 0.96A 5tudD-1rw0A:
undetectable		 5tudD-1rw0A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzr GLUCOSE-RESISTANCE
AMYLASE REGULATOR

(Bacillus
megaterium) 		no annotation 5 LEU G 113
VAL G 117
THR G  62
LEU G 144
GLU G 105
 None
 1.50A 5tudD-1rzrG:
undetectable		 5tudD-1rzrG:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sus CAFFEOYL-COA
O-METHYLTRANSFERASE

(Medicago sativa) 		PF01596
(Methyltransf_3) 		4 LEU A  49
LEU A  95
LEU A  75
GLU A  67
 None
 0.87A 5tudD-1susA:
undetectable		 5tudD-1susA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1szn ALPHA-GALACTOSIDASE

(Trichoderma
reesei) 		PF16499
(Melibiase_2) 		4 LEU A 353
VAL A 355
THR A 357
LEU A 259
 None
 0.80A 5tudD-1sznA:
undetectable		 5tudD-1sznA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t33 PUTATIVE
TRANSCRIPTIONAL
REPRESSOR (TETR/ACRR
FAMILY)

(Salmonella
enterica) 		PF00440
(TetR_N)
PF09209
(DUF1956) 		4 LEU A 148
VAL A 152
THR A 156
LEU A 173
 None
 0.85A 5tudD-1t33A:
3.2		 5tudD-1t33A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tq8 HYPOTHETICAL PROTEIN
RV1636

(Mycobacterium
tuberculosis) 		PF00582
(Usp) 		4 LEU A 123
VAL A 125
LEU A 111
GLU A  99
 None
 0.81A 5tudD-1tq8A:
undetectable		 5tudD-1tq8A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tuf DIAMINOPIMELATE
DECARBOXYLASE

(Methanocaldococcus
jannaschii) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 LEU A 316
VAL A  48
THR A 420
GLU A 432
 None
 0.77A 5tudD-1tufA:
undetectable		 5tudD-1tufA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ACTIN-RELATED
PROTEIN 3

(Bos taurus) 		PF00022
(Actin) 		5 VAL A  10
THR A 113
LEU A 101
LEU A   5
GLU A 106
 None
 1.33A 5tudD-1u2vA:
undetectable		 5tudD-1u2vA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u6g TIP120 PROTEIN

(Homo sapiens) 		PF08623
(TIP120) 		4 LEU C1004
LEU C1040
LEU C1045
GLU C1016
 None
 0.98A 5tudD-1u6gC:
undetectable		 5tudD-1u6gC:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vp8 HYPOTHETICAL PROTEIN
AF0103

(Archaeoglobus
fulgidus) 		PF02887
(PK_C) 		4 VAL A  59
THR A  61
LEU A  49
GLU A  17
 None
 0.95A 5tudD-1vp8A:
undetectable		 5tudD-1vp8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x2g LIPOATE-PROTEIN
LIGASE A

(Escherichia
coli) 		PF03099
(BPL_LplA_LipB)
PF10437
(Lip_prot_lig_C) 		4 LEU A 123
VAL A 125
THR A 127
LEU A 108
 None
 0.90A 5tudD-1x2gA:
undetectable		 5tudD-1x2gA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x51 A/G-SPECIFIC ADENINE
DNA GLYCOSYLASE

(Homo sapiens) 		PF14815
(NUDIX_4) 		4 LEU A  73
LEU A  26
LEU A 125
GLU A  52
 None
 0.88A 5tudD-1x51A:
undetectable		 5tudD-1x51A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x99 LECTIN

(Xerocomellus
chrysenteron) 		PF07367
(FB_lectin) 		4 LEU A   9
VAL A  11
LEU A  57
LEU A  86
 None
 0.94A 5tudD-1x99A:
undetectable		 5tudD-1x99A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xc6 BETA-GALACTOSIDASE

(Penicillium sp.) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		4 LEU A 152
THR A 706
LEU A 159
GLU A 164
 None
 0.77A 5tudD-1xc6A:
undetectable		 5tudD-1xc6A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xq9 PHOSPHOGLYCERATE
MUTASE

(Plasmodium
falciparum) 		PF00300
(His_Phos_1) 		4 VAL A  63
THR A  65
LEU A 238
GLU A 225
 None
 0.90A 5tudD-1xq9A:
undetectable		 5tudD-1xq9A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y8a HYPOTHETICAL PROTEIN
AF1437

(Archaeoglobus
fulgidus) 		no annotation 4 THR A   4
LEU A  12
LEU A  17
GLU A 306
 None
 0.95A 5tudD-1y8aA:
undetectable		 5tudD-1y8aA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ybe NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Agrobacterium
tumefaciens) 		PF04095
(NAPRTase) 		4 LEU A 279
LEU A  48
LEU A 258
GLU A 250
 None
 0.90A 5tudD-1ybeA:
undetectable		 5tudD-1ybeA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yt3 RIBONUCLEASE D

(Escherichia
coli) 		PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1) 		4 LEU A 275
VAL A 279
LEU A 258
GLU A 242
 None
 0.96A 5tudD-1yt3A:
undetectable		 5tudD-1yt3A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zcw AROMATIC
PRENYLTRANSFERASE

(Streptomyces
sp. CL190) 		PF11468
(PTase_Orf2) 		4 LEU A  95
VAL A  91
LEU A  83
GLU A  80
 None
 0.98A 5tudD-1zcwA:
undetectable		 5tudD-1zcwA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq1 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D

(Pyrococcus
abyssi) 		PF00710
(Asparaginase) 		4 VAL A 172
THR A  95
LEU A 192
GLU A 295
 None
 0.98A 5tudD-1zq1A:
undetectable		 5tudD-1zq1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zq1 GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D

(Pyrococcus
abyssi) 		PF00710
(Asparaginase) 		4 VAL A 172
THR A  95
LEU A 195
GLU A 229
 None
 0.90A 5tudD-1zq1A:
undetectable		 5tudD-1zq1A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ako GLUTAMATE 5-KINASE

(Campylobacter
jejuni) 		PF00696
(AA_kinase) 		5 LEU A  42
VAL A   5
THR A 150
LEU A 240
GLU A  36
 None
 1.43A 5tudD-2akoA:
undetectable		 5tudD-2akoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azo MUTH

(Escherichia
coli) 		PF02976
(MutH) 		4 LEU A 221
LEU A 142
LEU A  17
GLU A  77
 None
 0.91A 5tudD-2azoA:
undetectable		 5tudD-2azoA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azp HYPOTHETICAL PROTEIN
PA1268

(Pseudomonas
aeruginosa) 		PF05544
(Pro_racemase) 		5 LEU A  64
VAL A  76
THR A 114
LEU A  18
LEU A  59
 None
 1.28A 5tudD-2azpA:
undetectable		 5tudD-2azpA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bjs ISOPENICILLIN N
SYNTHETASE

(Aspergillus
nidulans) 		PF03171
(2OG-FeII_Oxy)
PF14226
(DIOX_N) 		4 LEU A 231
VAL A 233
THR A 235
LEU A 250
 None
 0.83A 5tudD-2bjsA:
undetectable		 5tudD-2bjsA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cb0 GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Pyrococcus
furiosus) 		PF01380
(SIS) 		4 LEU A 241
VAL A 239
THR A 237
LEU A 253
 None
 0.89A 5tudD-2cb0A:
undetectable		 5tudD-2cb0A:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3y URACIL-DNA
GLYCOSYLASE

(Thermus
thermophilus) 		PF03167
(UDG) 		4 LEU A 155
THR A 110
LEU A 185
LEU A 216
 None
 0.80A 5tudD-2d3yA:
undetectable		 5tudD-2d3yA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5v HEPATOCYTE NUCLEAR
FACTOR 6

(Rattus
norvegicus) 		PF00046
(Homeobox)
PF02376
(CUT) 		4 VAL A 107
THR A 105
LEU A 126
GLU A 118
 None
 0.84A 5tudD-2d5vA:
undetectable		 5tudD-2d5vA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dzm FAS-ASSOCIATED
FACTOR 1

(Homo sapiens) 		no annotation 4 LEU A  76
VAL A  78
THR A  80
GLU A  60
 None
 0.89A 5tudD-2dzmA:
undetectable		 5tudD-2dzmA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5f HYPOTHETICAL PROTEIN
PH0510

(Pyrococcus
horikoshii) 		PF01380
(SIS) 		4 LEU A 241
VAL A 239
THR A 237
LEU A 253
 None
 0.91A 5tudD-2e5fA:
undetectable		 5tudD-2e5fA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ejw HOMOSERINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00742
(Homoserine_dh)
PF03447
(NAD_binding_3) 		4 LEU A 202
VAL A 204
LEU A 134
LEU A 279
 None
 0.93A 5tudD-2ejwA:
undetectable		 5tudD-2ejwA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2b AQUAPORIN AQPM

(Methanothermobacter
marburgensis) 		PF00230
(MIP) 		4 VAL A 183
THR A 182
LEU A  18
LEU A  73
 None
None
GOL  A 501 (-4.7A)
None
 0.88A 5tudD-2f2bA:
undetectable		 5tudD-2f2bA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f6r BIFUNCTIONAL
COENZYME A SYNTHASE

(Mus musculus) 		PF01121
(CoaE) 		4 THR A  69
LEU A  46
LEU A 256
GLU A 251
 None
 0.84A 5tudD-2f6rA:
undetectable		 5tudD-2f6rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fsn HYPOTHETICAL PROTEIN
TA0583

(Thermoplasma
acidophilum) 		no annotation 4 VAL A 277
THR A 301
LEU A 198
GLU A 193
 None
 0.95A 5tudD-2fsnA:
undetectable		 5tudD-2fsnA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus) 		PF00343
(Phosphorylase) 		4 LEU A 198
VAL A 200
LEU A 349
GLU A 357
 None
 0.85A 5tudD-2gj4A:
undetectable		 5tudD-2gj4A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gpj SIDEROPHORE-INTERACT
ING PROTEIN

(Shewanella
putrefaciens) 		PF04954
(SIP)
PF08021
(FAD_binding_9) 		4 LEU A 130
THR A  61
LEU A 116
LEU A 205
 None
FAD  A 500 (-4.0A)
None
None
 0.97A 5tudD-2gpjA:
undetectable		 5tudD-2gpjA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hsz NOVEL PREDICTED
PHOSPHATASE

(Histophilus
somni) 		PF13419
(HAD_2) 		4 LEU A 114
VAL A 116
THR A 118
LEU A 104
 None
 0.94A 5tudD-2hszA:
undetectable		 5tudD-2hszA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iae SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 LEU B  73
VAL B  77
THR B  81
LEU B 182
 None
 0.89A 5tudD-2iaeB:
undetectable		 5tudD-2iaeB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icu HYPOTHETICAL PROTEIN
YEDK

(Escherichia
coli) 		PF02586
(SRAP) 		4 LEU A  53
VAL A  51
LEU A  80
GLU A 150
 None
 0.94A 5tudD-2icuA:
undetectable		 5tudD-2icuA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2if6 HYPOTHETICAL PROTEIN
YIIX

(Escherichia
coli) 		PF05708
(Peptidase_C92) 		4 VAL A  54
THR A  23
LEU A 111
GLU A 130
 None
None
None
UNX  A   1 (-2.2A)
 0.96A 5tudD-2if6A:
undetectable		 5tudD-2if6A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ixq PROTEIN AFAD

(Escherichia
coli) 		PF05775
(AfaD) 		4 LEU A  16
THR A 142
LEU A   6
GLU A  42
 LEU  A  16 ( 0.4A)
THR  A 142 ( 0.2A)
LEU  A   6 ( 0.5A)
GLU  A  42 ( 0.5A)
 0.96A 5tudD-2ixqA:
undetectable		 5tudD-2ixqA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6h GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF01380
(SIS)
PF13522
(GATase_6) 		5 LEU A 415
VAL A 411
THR A 407
LEU A 371
LEU A 298
 None
 1.24A 5tudD-2j6hA:
1.8		 5tudD-2j6hA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jak SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 LEU A  73
VAL A  77
THR A  81
GLU A 178
 None
 0.98A 5tudD-2jakA:
undetectable		 5tudD-2jakA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jak SERINE/THREONINE-PRO
TEIN PHOSPHATASE 2A
56 KDA REGULATORY
SUBUNIT GAMMA
ISOFORM

(Homo sapiens) 		PF01603
(B56) 		4 LEU A  73
VAL A  77
THR A  81
LEU A 182
 None
 0.63A 5tudD-2jakA:
undetectable		 5tudD-2jakA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jfe CYTOSOLIC
BETA-GLUCOSIDASE

(Homo sapiens) 		PF00232
(Glyco_hydro_1) 		4 VAL X 220
LEU X 118
LEU X 197
GLU X 165
 None
 0.76A 5tudD-2jfeX:
undetectable		 5tudD-2jfeX:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l6f FOCAL ADHESION
KINASE 1, LINKER1,
PAXILLIN, LINKER2,
PAXILLIN

(Gallus gallus;
unidentified) 		PF03535
(Paxillin)
PF03623
(Focal_AT) 		4 LEU A  80
LEU A 124
LEU A  65
GLU A  60
 None
 0.95A 5tudD-2l6fA:
8.3		 5tudD-2l6fA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lgx FERMITIN FAMILY
HOMOLOG 2

(Homo sapiens) 		no annotation 5 VAL A  24
THR A  25
LEU A  48
LEU A  79
GLU A  19
 None
 1.24A 5tudD-2lgxA:
undetectable		 5tudD-2lgxA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o78 PUTATIVE HISTIDINE
AMMONIA-LYASE

(Rhodobacter
sphaeroides) 		PF00221
(Lyase_aromatic) 		4 LEU A 201
THR A 331
LEU A 129
GLU A 123
 None
 0.96A 5tudD-2o78A:
2.6		 5tudD-2o78A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ool SENSOR PROTEIN

(Rhodopseudomonas
palustris) 		PF01590
(GAF)
PF08446
(PAS_2) 		4 LEU A 107
VAL A 109
THR A 111
LEU A 131
 None
 0.99A 5tudD-2oolA:
2.1		 5tudD-2oolA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2own PUTATIVE
OLEOYL-[ACYL-CARRIER
PROTEIN]
THIOESTERASE

(Lactobacillus
plantarum) 		PF01643
(Acyl-ACP_TE) 		4 LEU A 225
VAL A 233
THR A 255
LEU A 187
 None
 0.98A 5tudD-2ownA:
undetectable		 5tudD-2ownA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pcq PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE

(Thermus
thermophilus) 		PF00701
(DHDPS) 		4 LEU A  81
LEU A  92
LEU A 123
GLU A 113
 None
 0.96A 5tudD-2pcqA:
undetectable		 5tudD-2pcqA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pl3 PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX10

(Homo sapiens) 		PF00270
(DEAD) 		4 VAL A 239
THR A 235
LEU A 145
LEU A 250
 None
 0.92A 5tudD-2pl3A:
undetectable		 5tudD-2pl3A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pq7 PREDICTED HD
SUPERFAMILY
HYDROLASE

(uncultured
Thermotogales
bacterium) 		PF01966
(HD) 		4 LEU A 133
VAL A  40
THR A  37
LEU A 122
 None
 0.98A 5tudD-2pq7A:
undetectable		 5tudD-2pq7A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2prz OROTATE
PHOSPHORIBOSYLTRANSF
ERASE 1

(Saccharomyces
cerevisiae) 		PF00156
(Pribosyltran) 		4 LEU A  40
VAL A 133
THR A 135
LEU A 202
 None
OMP  A 450 (-4.4A)
OMP  A 450 (-2.8A)
None
 0.94A 5tudD-2przA:
undetectable		 5tudD-2przA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pso STAR-RELATED LIPID
TRANSFER PROTEIN 13

(Homo sapiens) 		PF01852
(START) 		4 LEU A1032
VAL A1030
THR A1028
GLU A 988
 None
 0.90A 5tudD-2psoA:
undetectable		 5tudD-2psoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qa1 POLYKETIDE OXYGENASE
PGAE

(Streptomyces
sp. PGA64) 		PF01494
(FAD_binding_3) 		4 LEU A 123
VAL A 120
LEU A 148
LEU A  17
 None
FAD  A 500 (-4.1A)
None
None
 0.98A 5tudD-2qa1A:
undetectable		 5tudD-2qa1A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe7 ATP SYNTHASE SUBUNIT
BETA

(Bacillus sp.
TA2.A1) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 LEU D 226
THR D 314
LEU D 242
LEU D 128
 None
 0.94A 5tudD-2qe7D:
undetectable		 5tudD-2qe7D:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qty POLY(ADP-RIBOSE)
GLYCOHYDROLASE ARH3

(Mus musculus) 		PF03747
(ADP_ribosyl_GH) 		4 LEU A  32
VAL A  30
LEU A 251
GLU A 246
 None
 0.98A 5tudD-2qtyA:
undetectable		 5tudD-2qtyA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qvg TWO COMPONENT
RESPONSE REGULATOR

(Legionella
pneumophila) 		PF00072
(Response_reg) 		4 LEU A 132
LEU A  62
LEU A  13
GLU A  37
 None
 0.89A 5tudD-2qvgA:
undetectable		 5tudD-2qvgA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6r CELL DIVISION
PROTEIN FTSZ

(Aquifex
aeolicus) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 LEU 1 186
VAL 1 190
THR 1 194
LEU 1 219
 None
 0.96A 5tudD-2r6r1:
undetectable		 5tudD-2r6r1:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfo NUCLEOPORIN NIC96

(Saccharomyces
cerevisiae) 		PF04097
(Nic96) 		4 LEU A 579
LEU A 557
LEU A 610
GLU A 606
 None
 0.90A 5tudD-2rfoA:
undetectable		 5tudD-2rfoA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uwj TYPE III EXPORT
PROTEIN PSCE
TYPE III EXPORT
PROTEIN PSCF
TYPE III EXPORT
PROTEIN PSCG

(Pseudomonas
aeruginosa) 		PF08988
(T3SS_needle_E)
PF09392
(T3SS_needle_F)
PF09477
(Type_III_YscG) 		4 LEU E  27
LEU G   9
LEU F  82
GLU E   9
 None
 0.95A 5tudD-2uwjE:
4.3		 5tudD-2uwjE:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uzx HEPATOCYTE GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		4 LEU B 120
VAL B 122
THR B 124
GLU B  83
 None
 0.92A 5tudD-2uzxB:
undetectable		 5tudD-2uzxB:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ve3 PUTATIVE CYTOCHROME
P450 120

(Synechocystis
sp. PCC 6803) 		PF00067
(p450) 		4 LEU A 121
THR A 157
LEU A 403
GLU A 395
 None
 0.93A 5tudD-2ve3A:
1.4		 5tudD-2ve3A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vkc NEDD4-BINDING
PROTEIN 2

(Homo sapiens) 		PF01713
(Smr) 		4 LEU A1725
VAL A1727
THR A1729
LEU A1709
 None
 0.93A 5tudD-2vkcA:
undetectable		 5tudD-2vkcA:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgy CYTOCHROME P450 130

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		5 LEU A 283
VAL A 337
THR A 338
LEU A 259
GLU A 370
 None
 1.46A 5tudD-2wgyA:
2.0		 5tudD-2wgyA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wym L-ASCORBATE-6-PHOSPH
ATE LACTONASE ULAG

(Escherichia
coli) 		PF13483
(Lactamase_B_3) 		4 LEU A  50
VAL A  60
LEU A 221
GLU A 176
 None
 0.94A 5tudD-2wymA:
undetectable		 5tudD-2wymA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x49 INVASION PROTEIN
INVA

(Salmonella
enterica) 		PF00771
(FHIPEP) 		5 LEU A 478
VAL A 425
THR A 424
LEU A 379
GLU A 372
 None
 1.43A 5tudD-2x49A:
undetectable		 5tudD-2x49A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y05 PROSTAGLANDIN
REDUCTASE 1

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 LEU A  38
VAL A  71
THR A  83
LEU A  32
 None
 0.94A 5tudD-2y05A:
undetectable		 5tudD-2y05A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yu1 JMJC
DOMAIN-CONTAINING
HISTONE
DEMETHYLATION
PROTEIN 1A

(Homo sapiens) 		PF02373
(JmjC) 		4 LEU A 337
VAL A 341
THR A 345
GLU A 459
 None
 0.73A 5tudD-2yu1A:
undetectable		 5tudD-2yu1A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0m 337AA LONG
HYPOTHETICAL
ATP-DEPENDENT RNA
HELICASE DEAD

(Sulfurisphaera
tokodaii) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		4 VAL A 133
THR A 163
LEU A 116
GLU A  89
 None
 0.97A 5tudD-2z0mA:
undetectable		 5tudD-2z0mA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1a 5'-NUCLEOTIDASE

(Thermus
thermophilus) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		4 LEU A 492
LEU A 411
LEU A 470
GLU A 421
 None
 0.91A 5tudD-2z1aA:
undetectable		 5tudD-2z1aA:
22.13