SIMILAR PATTERNS OF AMINO ACIDS FOR 5TUD_A_ERMA2001_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dgm ADENOSINE KINASE

(Toxoplasma
gondii) 		PF00294
(PfkB) 		4 THR A 246
LEU A 220
VAL A 321
GLU A 288
 None
 1.13A 5tudA-1dgmA:
undetectable		 5tudA-1dgmA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f9k ACIDIC LECTIN

(Psophocarpus
tetragonolobus) 		PF00139
(Lectin_legB) 		4 THR A  34
VAL A 135
GLN A 154
GLU A 156
 None
 1.05A 5tudA-1f9kA:
undetectable		 5tudA-1f9kA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyq PROTEIN
(GLYCERALDEHYDE-3-PH
OSPHATE
DEHYDROGENASE)

(Leishmania
mexicana) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 THR A 168
LEU A 346
VAL A  17
GLN A  24
 None
 1.13A 5tudA-1gyqA:
undetectable		 5tudA-1gyqA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jmo HEPARIN COFACTOR II

(Homo sapiens) 		PF00079
(Serpin) 		4 THR A 187
LEU A 148
VAL A 158
GLU A 175
 None
 0.95A 5tudA-1jmoA:
0.4		 5tudA-1jmoA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js4 ENDO/EXOCELLULASE E4

(Thermobifida
fusca) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 LEU A  10
ASN A 430
VAL A 364
GLU A  18
 None
 1.08A 5tudA-1js4A:
2.3		 5tudA-1js4A:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kqj A/G-SPECIFIC ADENINE
GLYCOSYLASE

(Escherichia
coli) 		PF00633
(HHH)
PF00730
(HhH-GPD) 		4 THR A  63
LEU A 114
GLN A  41
GLU A  37
 None
 1.13A 5tudA-1kqjA:
0.0		 5tudA-1kqjA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pff METHIONINE
GAMMA-LYASE

(Trichomonas
vaginalis) 		PF01053
(Cys_Met_Meta_PP) 		4 LEU A 327
LYS A 325
VAL A 395
GLN A 390
 None
 0.91A 5tudA-1pffA:
0.0		 5tudA-1pffA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qpo QUINOLINATE ACID
PHOSPHORIBOSYL
TRANSFERASE

(Mycobacterium
tuberculosis) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 THR A  42
LEU A  60
VAL A 111
GLU A  65
 None
 1.13A 5tudA-1qpoA:
0.0		 5tudA-1qpoA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8d 2,4-DIENOYL-COA
REDUCTASE,
MITOCHONDRIAL
PRECURSOR

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 LEU A 224
ASN A 143
VAL A 141
GLU A 218
 None
 1.10A 5tudA-1w8dA:
0.0		 5tudA-1w8dA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ycl S-RIBOSYLHOMOCYSTEIN
ASE

(Bacillus
subtilis) 		PF02664
(LuxS) 		4 LEU A 140
LYS A 138
VAL A 113
GLU A  57
 None
None
None
KRI  A 401 (-3.1A)
 0.94A 5tudA-1yclA:
0.1		 5tudA-1yclA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z05 TRANSCRIPTIONAL
REGULATOR, ROK
FAMILY

(Vibrio cholerae) 		PF00480
(ROK) 		4 LEU A 321
VAL A 328
GLN A 361
GLU A 360
 None
None
BME  A 413 ( 4.8A)
BME  A 413 (-3.6A)
 1.08A 5tudA-1z05A:
undetectable		 5tudA-1z05A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zs6 NUCLEOSIDE
DIPHOSPHATE KINASE 3

(Homo sapiens) 		PF00334
(NDK) 		4 THR A 111
LEU A  26
VAL A  90
GLU A  40
 ADP  A 201 (-2.9A)
None
None
None
 1.10A 5tudA-1zs6A:
undetectable		 5tudA-1zs6A:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ani RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA SUBUNIT

(Chlamydia
trachomatis) 		PF00268
(Ribonuc_red_sm) 		4 THR A 126
LEU A 205
ASN A  81
GLU A  74
 None
 1.08A 5tudA-2aniA:
undetectable		 5tudA-2aniA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 THR A 860
LEU A 816
VAL A 870
GLU A 875
 None
 1.00A 5tudA-2b5mA:
undetectable		 5tudA-2b5mA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cso PLECKSTRIN

(Homo sapiens) 		PF00610
(DEP) 		4 THR A  49
LEU A  70
VAL A  63
GLU A  79
 None
 1.09A 5tudA-2csoA:
undetectable		 5tudA-2csoA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d04 CURCULIN
NEOCULIN ACIDIC
SUBUNIT

(Molineria
latifolia) 		PF01453
(B_lectin) 		4 LEU B  86
ASN B   2
VAL A   3
GLN A  90
 None
 1.03A 5tudA-2d04B:
undetectable		 5tudA-2d04B:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e7c MYOSIN-BINDING
PROTEIN C, FAST-TYPE

(Homo sapiens) 		PF07679
(I-set) 		4 LEU A  44
VAL A  70
GLN A  41
GLU A  40
 None
 1.08A 5tudA-2e7cA:
undetectable		 5tudA-2e7cA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ecf DIPEPTIDYL PEPTIDASE
IV

(Stenotrophomonas
maltophilia) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 LEU A 289
LYS A 264
GLN A 285
GLU A 284
 None
 1.11A 5tudA-2ecfA:
undetectable		 5tudA-2ecfA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f4l ACETAMIDASE,
PUTATIVE

(Thermotoga
maritima) 		PF03069
(FmdA_AmdA) 		4 THR A 272
LEU A 160
LYS A  68
GLU A 204
 None
 1.04A 5tudA-2f4lA:
undetectable		 5tudA-2f4lA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmt METHIONYL-TRNA FMET
FORMYLTRANSFERASE

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 THR A 276
LEU A 286
GLN A 243
GLU A 241
 None
 0.97A 5tudA-2fmtA:
undetectable		 5tudA-2fmtA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmu PUTATIVE
PYRIDOXAMINE
5-PHOSPHATE-DEPENDEN
T DEHYDRASE, WBDK

(Escherichia
coli) 		PF01041
(DegT_DnrJ_EryC1) 		4 THR A 181
LEU A 135
ASN A 140
GLU A 295
 None
 0.96A 5tudA-2gmuA:
undetectable		 5tudA-2gmuA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gu0 NONSTRUCTURAL
PROTEIN 2

(Rotavirus C) 		PF02509
(Rota_NS35) 		4 THR A 187
LEU A 125
LYS A 119
ASN A 155
 None
 1.04A 5tudA-2gu0A:
undetectable		 5tudA-2gu0A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2opi L-FUCULOSE-1-PHOSPHA
TE ALDOLASE

(Bacteroides
thetaiotaomicron) 		PF00596
(Aldolase_II) 		4 THR A 100
LEU A  92
GLN A 169
GLU A 172
 None
 1.08A 5tudA-2opiA:
undetectable		 5tudA-2opiA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2px9 SUMO-ACTIVATING
ENZYME SUBUNIT 2

(Homo sapiens) 		PF10585
(UBA_e1_thiolCys) 		4 THR A 247
LEU A 192
GLN A 204
GLU A 199
 None
 0.96A 5tudA-2px9A:
2.1		 5tudA-2px9A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qf7 PYRUVATE CARBOXYLASE
PROTEIN

(Rhizobium etli) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF00682
(HMGL-like)
PF02436
(PYC_OADA)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 THR A 561
LEU A 476
VAL A 483
GLU A1021
 None
 1.11A 5tudA-2qf7A:
undetectable		 5tudA-2qf7A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qik UPF0131 PROTEIN YKQA

(Bacillus
subtilis) 		PF06094
(GGACT)
PF13772
(AIG2_2) 		4 LEU A 234
VAL A 208
GLN A 237
GLU A 239
 None
 1.09A 5tudA-2qikA:
undetectable		 5tudA-2qikA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2raa PYRUVATE SYNTHASE
SUBUNIT PORC

(Thermotoga
maritima) 		PF01558
(POR) 		4 THR A 139
ASN A  57
VAL A  38
GLU A  43
 None
 1.11A 5tudA-2raaA:
undetectable		 5tudA-2raaA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vhs CATHSILICATEIN

(Homo sapiens) 		PF00112
(Peptidase_C1) 		4 LEU A 144
ASN A 187
VAL A 199
GLU A 192
 None
 1.12A 5tudA-2vhsA:
undetectable		 5tudA-2vhsA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfn ALPHA-GALACTOSIDASE-
SUCROSE KINASE AGASK

([Ruminococcus]
gnavus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 THR A  82
LEU A 272
VAL A 292
GLU A 278
 None
None
None
MG  A1726 ( 4.9A)
 0.95A 5tudA-2yfnA:
undetectable		 5tudA-2yfnA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brn LIPOCALIN

(Argas
monolakensis) 		PF02098
(His_binding) 		4 THR A  85
LEU A  50
ASN A  78
GLN A  14
 None
 1.04A 5tudA-3brnA:
undetectable		 5tudA-3brnA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8v PUTATIVE
ACETYLTRANSFERASE

(Desulfovibrio
alaskensis) 		no annotation 4 THR A 164
LEU A 215
VAL A 230
GLU A 222
 None
 1.14A 5tudA-3c8vA:
undetectable		 5tudA-3c8vA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzc UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Vibrio cholerae) 		PF02350
(Epimerase_2) 		4 THR A 212
VAL A 181
GLN A 192
GLU A 196
 None
 1.06A 5tudA-3dzcA:
undetectable		 5tudA-3dzcA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fy6 INTEGRON CASSETTE
PROTEIN

(Vibrio cholerae) 		no annotation 4 THR A  53
VAL A 104
GLN A  99
GLU A  95
 None
 0.99A 5tudA-3fy6A:
2.4		 5tudA-3fy6A:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjr EXTRACELLULAR SERINE
PROTEASE

(Aeromonas
sobria) 		PF00082
(Peptidase_S8)
PF01483
(P_proprotein) 		4 THR A 339
LEU A 162
GLN A 202
GLU A 201
 None
 1.04A 5tudA-3hjrA:
undetectable		 5tudA-3hjrA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwn CATHEPSIN L1

(Homo sapiens) 		PF00112
(Peptidase_C1) 		4 LEU A 144
ASN A 187
VAL A 199
GLU A 192
 None
 1.07A 5tudA-3hwnA:
undetectable		 5tudA-3hwnA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kao TAGATOSE
1,6-DIPHOSPHATE
ALDOLASE

(Staphylococcus
aureus) 		PF01791
(DeoC) 		4 THR A  61
LEU A  89
LYS A 117
ASN A 122
 None
 1.02A 5tudA-3kaoA:
undetectable		 5tudA-3kaoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kda CFTR INHIBITORY
FACTOR (CIF)

(Pseudomonas
aeruginosa) 		no annotation 4 LEU D 242
ASN D 134
GLN D 105
GLU D 104
 None
 1.04A 5tudA-3kdaD:
undetectable		 5tudA-3kdaD:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kny HYPOTHETICAL PROTEIN
BT_3535

(Bacteroides
thetaiotaomicron) 		no annotation 4 THR A  64
LEU A 204
ASN A  94
GLU A  87
 None
 1.06A 5tudA-3knyA:
undetectable		 5tudA-3knyA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l84 TRANSKETOLASE

(Campylobacter
jejuni) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LYS A 244
ASN A  11
GLN A 271
GLU A 270
 None
 1.09A 5tudA-3l84A:
undetectable		 5tudA-3l84A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lml LIN1278 PROTEIN

(Listeria
innocua) 		PF04984
(Phage_sheath_1)
PF17481
(Phage_sheath_1N)
PF17482
(Phage_sheath_1C) 		4 THR A  80
ASN A 289
GLN A 333
GLU A 332
 None
 1.13A 5tudA-3lmlA:
undetectable		 5tudA-3lmlA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mga ENTEROCHELIN
ESTERASE

(Salmonella
enterica) 		PF00756
(Esterase)
PF11806
(DUF3327) 		4 THR A 320
LEU A 290
GLN A 285
GLU A 345
 None
 1.05A 5tudA-3mgaA:
undetectable		 5tudA-3mgaA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oby PROTEIN PELOTA
HOMOLOG

(Archaeoglobus
fulgidus) 		PF03463
(eRF1_1)
PF03464
(eRF1_2)
PF03465
(eRF1_3) 		4 THR A  21
LEU A 286
VAL A 308
GLU A 295
 None
 1.02A 5tudA-3obyA:
undetectable		 5tudA-3obyA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pp6 SODIUM-CALCIUM
EXCHANGER

(Doryteuthis
pealeii) 		PF00061
(Lipocalin) 		4 THR A  56
LYS A  22
ASN A  35
GLU A  15
 PAM  A 133 ( 4.6A)
None
None
None
 0.87A 5tudA-3pp6A:
undetectable		 5tudA-3pp6A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qci RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE GAMMA

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 THR A 859
LEU A1089
VAL A1072
GLN A1079
 None
 1.13A 5tudA-3qciA:
undetectable		 5tudA-3qciA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr2 BASIGIN

(Homo sapiens) 		PF13927
(Ig_3) 		4 THR A  71
VAL A 115
GLN A  40
GLU A  38
 None
 1.09A 5tudA-3qr2A:
undetectable		 5tudA-3qr2A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u22 PUTATIVE HMUY_LIKE
HEME BINDING PROTEIN

(Bacteroides
vulgatus) 		PF14064
(HmuY) 		4 THR A  65
LEU A 197
VAL A 167
GLU A 160
 SO4  A 309 ( 4.9A)
None
None
None
 1.13A 5tudA-3u22A:
undetectable		 5tudA-3u22A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9s METHYLCROTONYL-COA
CARBOXYLASE,
ALPHA-SUBUNIT

(Pseudomonas
aeruginosa) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		4 THR A 320
LEU A 368
GLN A 374
GLU A 373
 None
 1.10A 5tudA-3u9sA:
undetectable		 5tudA-3u9sA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uzb BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Deinococcus
radiodurans) 		PF01063
(Aminotran_4) 		4 THR A 267
LEU A 279
GLN A 252
GLU A 282
 PLP  A 371 (-3.5A)
None
None
None
 1.03A 5tudA-3uzbA:
undetectable		 5tudA-3uzbA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vcz ENDORIBONUCLEASE
L-PSP

(Vibrio
vulnificus) 		PF01042
(Ribonuc_L-PSP) 		4 LEU A  28
VAL A  61
GLN A  32
GLU A 121
 None
 1.09A 5tudA-3vczA:
undetectable		 5tudA-3vczA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnp CYCLOISOMALTOOLIGOSA
CCHARIDE
GLUCANOTRANSFERASE

(Bacillus
circulans) 		PF13199
(Glyco_hydro_66)
PF16990
(CBM_35) 		4 ASN A 734
VAL A 727
GLN A 708
GLU A 706
 None
 0.91A 5tudA-3wnpA:
undetectable		 5tudA-3wnpA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zvt D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE

(Actinomadura
sp. R39) 		PF02113
(Peptidase_S13) 		4 THR A  71
VAL A 260
GLN A  86
GLU A  76
 None
 0.97A 5tudA-3zvtA:
undetectable		 5tudA-3zvtA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 THR A 121
VAL A1205
GLN A 744
GLU A 745
 None
 1.12A 5tudA-3zyvA:
undetectable		 5tudA-3zyvA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b2q ATP SYNTHASE SUBUNIT
DELTA, MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF02823
(ATP-synt_DE_N) 		4 LEU H 105
VAL H 129
GLN H 134
GLU H  99
 None
 0.77A 5tudA-4b2qH:
3.0		 5tudA-4b2qH:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4br6 SUPEROXIDE DISMUTASE

(Chaetomium
thermophilum) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 THR A 189
LEU A 138
VAL A 141
GLN A 113
 None
 1.05A 5tudA-4br6A:
undetectable		 5tudA-4br6A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cq1 POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 2

(Homo sapiens) 		PF00076
(RRM_1)
PF13893
(RRM_5) 		4 THR A 351
LEU A 436
VAL A 524
GLN A 448
 None
 1.06A 5tudA-4cq1A:
undetectable		 5tudA-4cq1A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d9r COMPLEMENT FACTOR D

(Homo sapiens) 		PF00089
(Trypsin) 		4 LEU A 105
VAL A  85
GLN A  50
GLU A  49
 None
 1.04A 5tudA-4d9rA:
undetectable		 5tudA-4d9rA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4evf GIARDIN SUBUNIT
ALPHA-1

(Giardia
intestinalis) 		PF00191
(Annexin) 		4 THR A 207
LEU A 162
ASN A 197
GLU A 191
 None
 1.02A 5tudA-4evfA:
undetectable		 5tudA-4evfA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gyp GLUCARATE
DEHYDRATASE-RELATED
PROTEIN

(Escherichia
coli) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 THR C 256
VAL C 187
GLN C 214
GLU C 213
 None
 1.12A 5tudA-4gypC:
undetectable		 5tudA-4gypC:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hou INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 1

(Homo sapiens) 		PF13181
(TPR_8)
PF13424
(TPR_12) 		4 LEU A  57
ASN A 100
VAL A  96
GLU A  77
 None
 0.99A 5tudA-4houA:
2.2		 5tudA-4houA:
20.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		5 LEU A 209
LYS A 211
ASN A 344
VAL A 348
GLU A 363
 ERM  A2001 (-3.7A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.9A)
ERM  A2001 ( 4.5A)
 0.93A 5tudA-4ib4A:
38.9		 5tudA-4ib4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ib4 CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		6 THR A 140
LEU A 209
LYS A 211
ASN A 344
VAL A 348
GLN A 359
 ERM  A2001 (-3.9A)
ERM  A2001 (-3.7A)
None
ERM  A2001 (-4.3A)
ERM  A2001 ( 4.9A)
None
 0.44A 5tudA-4ib4A:
38.9		 5tudA-4ib4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkm BETA-GLUCURONIDASE

(Clostridium
perfringens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 THR A 383
LEU A 430
LYS A 432
VAL A 441
 None
 1.10A 5tudA-4jkmA:
undetectable		 5tudA-4jkmA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k6m POLYPROTEIN

(Japanese
encephalitis
virus) 		PF00972
(Flavi_NS5)
PF01728
(FtsJ) 		4 THR A 236
VAL A 164
GLN A 159
GLU A 155
 None
 0.92A 5tudA-4k6mA:
undetectable		 5tudA-4k6mA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4leo RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 THR C 280
LEU C 575
LYS C 578
ASN C 256
 None
 1.09A 5tudA-4leoC:
undetectable		 5tudA-4leoC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg3 UNCHARACTERIZED
PROTEIN

(Desulfovibrio
piger) 		PF16175
(DUF4875) 		4 THR A 107
LEU A 151
LYS A 157
GLU A  63
 None
None
None
SO4  A 302 ( 4.8A)
 1.12A 5tudA-4lg3A:
undetectable		 5tudA-4lg3A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfu EDS1

(Arabidopsis
thaliana) 		PF01764
(Lipase_3) 		4 THR A 248
LEU A 291
ASN A 286
VAL A 284
 None
 1.09A 5tudA-4nfuA:
undetectable		 5tudA-4nfuA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvh MALTOSE-BINDING
PERIPLASMIC PROTEIN,
4'-PHOSPHOPANTETHEIN
YL TRANSFERASE
CHIMERA

(Escherichia
coli;
Mycobacterium
tuberculosis) 		PF01648
(ACPS)
PF13416
(SBP_bac_8) 		4 THR A 373
LEU A 462
VAL A 482
GLU A 487
 GOL  A 605 (-4.9A)
COA  A 602 (-3.8A)
None
MG  A 603 ( 3.3A)
 0.97A 5tudA-4qvhA:
undetectable		 5tudA-4qvhA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rck HYPOTHETICAL
MEMBRANE SPANNING
PROTEIN

(Aliivibrio
fischeri) 		PF00092
(VWA) 		4 LEU A  63
VAL A  66
GLN A  88
GLU A  87
 None
 1.08A 5tudA-4rckA:
undetectable		 5tudA-4rckA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rza PRE-MRNA-SPLICING
FACTOR 38A

(Homo sapiens) 		PF03371
(PRP38) 		4 THR A  74
LEU A 120
LYS A 118
GLU A  94
 None
 1.08A 5tudA-4rzaA:
undetectable		 5tudA-4rzaA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3j CORTICAL-LYTIC
ENZYME

(Bacillus cereus) 		PF00704
(Glyco_hydro_18)
PF01476
(LysM) 		4 THR A 248
LYS A 197
GLN A 204
GLU A 207
 None
 1.06A 5tudA-4s3jA:
undetectable		 5tudA-4s3jA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tw5 EPS1P

(Saccharomyces
cerevisiae) 		PF00085
(Thioredoxin) 		4 LEU A 179
VAL A 227
GLN A 159
GLU A 157
 None
 1.14A 5tudA-4tw5A:
undetectable		 5tudA-4tw5A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u4p STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2

(Homo sapiens) 		PF06470
(SMC_hinge) 		4 THR A 574
LEU A 529
VAL A 610
GLN A 679
 None
 1.05A 5tudA-4u4pA:
4.9		 5tudA-4u4pA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uwa RYANODINE RECEPTOR 1

(Oryctolagus
cuniculus) 		PF00622
(SPRY)
PF01365
(RYDR_ITPR)
PF02026
(RyR)
PF02815
(MIR)
PF08709
(Ins145_P3_rec) 		4 LEU A2930
LYS A2928
VAL A2865
GLU A2870
 None
 1.11A 5tudA-4uwaA:
undetectable		 5tudA-4uwaA:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wdr HALOALKANE
DEHALOGENASE

(Sphingobium
japonicum) 		PF00561
(Abhydrolase_1) 		4 LEU A 248
VAL A 173
GLN A 146
GLU A 145
 None
 1.03A 5tudA-4wdrA:
undetectable		 5tudA-4wdrA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		4 THR A 116
VAL A1200
GLN A 739
GLU A 740
 None
 1.14A 5tudA-4yswA:
undetectable		 5tudA-4yswA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yw5 NEURAMINIDASE C

(Streptococcus
pneumoniae) 		PF02012
(BNR)
PF02973
(Sialidase)
PF13088
(BNR_2) 		4 THR A 273
VAL A 148
GLN A 129
GLU A 125
 None
 1.13A 5tudA-4yw5A:
undetectable		 5tudA-4yw5A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zlg PUTATIVE B-GLYCAN
PHOSPHORYLASE

(Saccharophagus
degradans) 		PF06165
(Glyco_transf_36)
PF17167
(Glyco_hydro_36) 		4 THR A 694
LEU A 648
LYS A 646
GLU A 320
 SO4  A 805 (-3.7A)
None
None
None
 1.13A 5tudA-4zlgA:
2.2		 5tudA-4zlgA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8f HUMAN SAFFOLD
VIRUS-3 VP1

(Cardiovirus B) 		no annotation 4 THR A 195
LEU A  69
VAL A 239
GLN A 112
 None
 1.04A 5tudA-5a8fA:
undetectable		 5tudA-5a8fA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4x LOW DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 8,
APOLIPOPROTEIN E
RECEPTOR, ISOFORM
CRA_E

(Homo sapiens) 		PF00057
(Ldl_recept_a)
PF00058
(Ldl_recept_b)
PF07645
(EGF_CA)
PF14670
(FXa_inhibition) 		4 THR B 460
LEU B 498
ASN B 457
GLU B 454
 None
 1.12A 5tudA-5b4xB:
undetectable		 5tudA-5b4xB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cb2 PROTEIN SEY1

(Candida
albicans) 		PF05879
(RHD3) 		4 THR A  69
LEU A 172
GLN A 315
GLU A 134
 GNP  A 702 (-4.4A)
None
None
None
 1.09A 5tudA-5cb2A:
4.8		 5tudA-5cb2A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cfc VP1

(Cardiovirus B) 		no annotation 4 THR A 195
LEU A  69
VAL A 239
GLN A 112
 None
 1.04A 5tudA-5cfcA:
undetectable		 5tudA-5cfcA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		4 THR A 336
LEU A 355
LYS A 353
GLU A 366
 None
 1.13A 5tudA-5czzA:
undetectable		 5tudA-5czzA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dku PREX DNA POLYMERASE

(Plasmodium
falciparum) 		PF00476
(DNA_pol_A)
PF01612
(DNA_pol_A_exo1) 		4 THR A 526
LEU A 555
VAL A 560
GLU A 602
 None
 1.09A 5tudA-5dkuA:
3.9		 5tudA-5dkuA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e76 SUSD-LIKE PROTEIN
BACOVA_02651

(Bacteroides
ovatus) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 LEU A 214
VAL A 245
GLN A 240
GLU A 236
 None
 1.11A 5tudA-5e76A:
3.7		 5tudA-5e76A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ijg CYS/MET METABOLISM
PYRIDOXAL-PHOSPHATE-
DEPENDENT ENZYME

(Brucella
melitensis) 		PF01053
(Cys_Met_Meta_PP) 		4 THR A 240
LEU A 255
VAL A 264
GLU A  86
 PLP  A 501 (-3.3A)
None
None
None
 1.13A 5tudA-5ijgA:
undetectable		 5tudA-5ijgA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7x DIMETHYLANILINE
MONOOXYGENASE,
PUTATIVE

(Aspergillus
flavus) 		PF00743
(FMO-like) 		4 THR A 420
LEU A 450
ASN A 517
GLN A 287
 None
 1.14A 5tudA-5j7xA:
undetectable		 5tudA-5j7xA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lf5 MYELIN-ASSOCIATED
GLYCOPROTEIN

(Mus musculus) 		PF08205
(C2-set_2)
PF13927
(Ig_3) 		4 LEU A 377
VAL A 331
GLN A 374
GLU A 372
 None
 1.00A 5tudA-5lf5A:
undetectable		 5tudA-5lf5A:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqc VP2

(Black queen
cell virus) 		PF00073
(Rhv) 		4 THR B 147
LEU B 171
VAL B 212
GLU B 166
 None
 1.10A 5tudA-5mqcB:
undetectable		 5tudA-5mqcB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtv EH DOMAIN-CONTAINING
PROTEIN 4

(Mus musculus) 		PF00350
(Dynamin_N)
PF16880
(EHD_N) 		4 THR A  72
LEU A  81
VAL A 103
GLN A  84
 None
 1.03A 5tudA-5mtvA:
2.1		 5tudA-5mtvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot1 PULLULANASE TYPE II,
GH13 FAMILY

(Thermococcus
kodakarensis) 		no annotation 5 THR A 602
LEU A 629
VAL A 673
GLN A 624
GLU A 621
 None
 1.38A 5tudA-5ot1A:
undetectable		 5tudA-5ot1A:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sv6 EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 3

(Methylophaga
aminisulfidivorans) 		PF00497
(SBP_bac_3) 		4 LEU A  60
VAL A  39
GLN A  53
GLU A  54
 None
 1.10A 5tudA-5sv6A:
undetectable		 5tudA-5sv6A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tsc UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 4 THR A 234
VAL A 345
GLN A 340
GLU A 336
 None
 1.10A 5tudA-5tscA:
undetectable		 5tudA-5tscA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ukg K-GECO

(Entacmaea
quadricolor) 		no annotation 4 THR A 230
LEU A  43
VAL A  84
GLU A  64
 None
 1.02A 5tudA-5ukgA:
undetectable		 5tudA-5ukgA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7c ACYLOXYACYL
HYDROLASE

(Homo sapiens) 		no annotation 4 THR C 290
LYS C 189
GLN C 178
GLU C 177
 None
 1.10A 5tudA-5w7cC:
undetectable		 5tudA-5w7cC:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wd6 SHORT PALATE, LUNG
AND NASAL EPITHELIUM
CARCINOMA-ASSOCIATED
PROTEIN 2B

(Bos taurus) 		no annotation 4 THR A 154
LEU A  89
VAL A 108
GLU A  81
 None
 1.03A 5tudA-5wd6A:
undetectable		 5tudA-5wd6A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5c CYSTEINE SYNTHASE

(Fusobacterium
nucleatum) 		no annotation 4 THR A  73
LEU A  54
VAL A  13
GLU A 155
 CL  A 402 (-4.1A)
MLY  A  55 ( 4.2A)
None
None
 0.94A 5tudA-5z5cA:
undetectable		 5tudA-5z5cA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbk PUTATIVE CYTOKININ
RIBOSIDE
5'-MONOPHOSPHATE
PHOSPHORIBOHYDROLASE

(Pseudomonas
aeruginosa) 		no annotation 4 LEU A 165
VAL A 119
GLN A 124
GLU A 160
 None
 1.10A 5tudA-5zbkA:
undetectable		 5tudA-5zbkA:
11.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bxg TAIL-SPECIFIC
PROTEASE

(Vibrio cholerae) 		no annotation 4 LEU A 319
VAL A 304
GLN A 288
GLU A 291
 None
 1.07A 5tudA-6bxgA:
undetectable		 5tudA-6bxgA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 1

(Homo sapiens) 		no annotation 4 THR C1122
LEU C1066
GLN C1032
GLU C1033
 None
 1.10A 5tudA-6en4C:
undetectable		 5tudA-6en4C:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fea NITROGENASE PROTEIN
ALPHA CHAIN

(Azotobacter
vinelandii) 		no annotation 5 LEU A 244
ASN A 206
VAL A 231
GLN A 249
GLU A 193
 None
 1.47A 5tudA-6feaA:
undetectable		 5tudA-6feaA:
11.26