SIMILAR PATTERNS OF AMINO ACIDS FOR 5TRQ_B_ACTB307

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0p SITE-SPECIFIC
RECOMBINASE XERD

(Escherichia
coli) 		PF00589
(Phage_integrase)
PF02899
(Phage_int_SAM_1) 		3 GLU A 285
HIS A 281
VAL A 264
 None
 0.41A 5trqB-1a0pA:
undetectable		 5trqB-1a0pA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1di6 MOLYBDENUM COFACTOR
BIOSYNTHETIC ENZYME

(Escherichia
coli) 		PF00994
(MoCF_biosynth) 		3 GLU A 144
HIS A 156
VAL A 181
 None
 0.84A 5trqB-1di6A:
0.0		 5trqB-1di6A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxy D-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Lactobacillus
casei) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 GLU A  12
HIS A 305
VAL A 304
 None
 0.89A 5trqB-1dxyA:
0.0		 5trqB-1dxyA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e5r PROLINE OXIDASE

(Streptomyces
sp. TH1) 		PF05118
(Asp_Arg_Hydrox)
PF05373
(Pro_3_hydrox_C) 		3 GLU A 247
HIS A 238
VAL A 243
 None
 0.86A 5trqB-1e5rA:
9.3		 5trqB-1e5rA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h5b MURINE T CELL
RECEPTOR (TCR)
VALPHA DOMAIN

(Mus musculus) 		PF07686
(V-set) 		3 GLU A  15
HIS A  14
VAL A 112
 None
 0.78A 5trqB-1h5bA:
0.0		 5trqB-1h5bA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kbe KINASE SUPPRESSOR OF
RAS

(Mus musculus) 		no annotation 3 GLU A 373
HIS A 367
VAL A 348
 None
ZN  A   2 (-3.0A)
ZN  A   2 ( 4.3A)
 0.73A 5trqB-1kbeA:
undetectable		 5trqB-1kbeA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ku2 SIGMA FACTOR SIGA

(Thermus
aquaticus) 		PF00140
(Sigma70_r1_2)
PF04539
(Sigma70_r3)
PF04542
(Sigma70_r2) 		3 GLU A 281
HIS A 278
VAL A 277
 None
 0.93A 5trqB-1ku2A:
undetectable		 5trqB-1ku2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lht MYOGLOBIN

(Caretta caretta) 		PF00042
(Globin) 		3 GLU A  27
HIS A  24
VAL A 114
 None
 0.88A 5trqB-1lhtA:
undetectable		 5trqB-1lhtA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m1l SUPPRESSOR OF FUSED

(Homo sapiens) 		PF05076
(SUFU) 		3 GLU A 207
HIS A 176
VAL A 203
 None
 0.83A 5trqB-1m1lA:
0.0		 5trqB-1m1lA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mo0 TRIOSEPHOSPHATE
ISOMERASE

(Caenorhabditis
elegans) 		PF00121
(TIM) 		3 GLU A 128
HIS A 137
VAL A 141
 None
 0.93A 5trqB-1mo0A:
undetectable		 5trqB-1mo0A:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1orp ENDONUCLEASE III

(Geobacillus
stearothermophilus) 		PF00633
(HHH)
PF00730
(HhH-GPD) 		3 GLU A 162
HIS A 178
VAL A 138
 None
 0.83A 5trqB-1orpA:
undetectable		 5trqB-1orpA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1otr PROTEIN CUE2

(Saccharomyces
cerevisiae) 		PF02845
(CUE) 		3 GLU A  34
HIS A  31
VAL A  30
 None
 0.91A 5trqB-1otrA:
undetectable		 5trqB-1otrA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s58 B19 PARVOVIRUS
CAPSID

(Primate
erythroparvovirus
1) 		PF00740
(Parvo_coat) 		3 GLU A 215
HIS A 216
VAL A 213
 None
 0.81A 5trqB-1s58A:
2.3		 5trqB-1s58A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkp IRON-RICH
DPSA-HOMOLOG PROTEIN

(Halobacterium
salinarum) 		PF00210
(Ferritin) 		3 GLU A  56
HIS A  64
VAL A  55
 None
 0.89A 5trqB-1tkpA:
undetectable		 5trqB-1tkpA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcn CTP SYNTHETASE

(Thermus
thermophilus) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		3 GLU A 131
HIS A 127
VAL A 108
 None
 0.63A 5trqB-1vcnA:
0.0		 5trqB-1vcnA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		3 GLU C 387
HIS C 390
VAL C 425
 None
 0.66A 5trqB-1w36C:
undetectable		 5trqB-1w36C:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a5v CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE)
(CARBONIC
DEHYDRATASE)

(Mycobacterium
tuberculosis) 		PF00484
(Pro_CA) 		3 GLU A 153
HIS A 156
VAL A 110
 None
 0.87A 5trqB-2a5vA:
undetectable		 5trqB-2a5vA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2abk ENDONUCLEASE III

(Escherichia
coli) 		PF00633
(HHH)
PF00730
(HhH-GPD)
PF10576
(EndIII_4Fe-2S) 		3 GLU A 160
HIS A 176
VAL A 137
 None
 0.85A 5trqB-2abkA:
undetectable		 5trqB-2abkA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ani RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
BETA SUBUNIT

(Chlamydia
trachomatis) 		PF00268
(Ribonuc_red_sm) 		3 GLU A 180
HIS A 103
VAL A 165
 None
 0.77A 5trqB-2aniA:
undetectable		 5trqB-2aniA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 GLU A 933
HIS A1348
VAL A 970
 None
 0.93A 5trqB-2b39A:
undetectable		 5trqB-2b39A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b39 C3

(Bos taurus) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		3 GLU A1137
HIS A1178
VAL A1140
 None
 0.92A 5trqB-2b39A:
undetectable		 5trqB-2b39A:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7s RNA-DEPENDENT RNA
POLYMERASE

(Foot-and-mouth
disease virus) 		PF00680
(RdRP_1) 		3 GLU A 286
HIS A  14
VAL A  15
 None
 0.92A 5trqB-2d7sA:
undetectable		 5trqB-2d7sA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dq3 SERYL-TRNA
SYNTHETASE

(Aquifex
aeolicus) 		PF00587
(tRNA-synt_2b)
PF02403
(Seryl_tRNA_N) 		3 GLU A 298
HIS A 291
VAL A 290
 None
 0.90A 5trqB-2dq3A:
undetectable		 5trqB-2dq3A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dy3 ALANINE RACEMASE

(Corynebacterium
glutamicum) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		3 GLU A 211
HIS A 195
VAL A 193
 None
 0.88A 5trqB-2dy3A:
undetectable		 5trqB-2dy3A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3q PROTEIN YBL047C

(Saccharomyces
cerevisiae) 		PF00627
(UBA) 		3 GLU A1356
HIS A1360
VAL A1346
 None
 0.90A 5trqB-2g3qA:
undetectable		 5trqB-2g3qA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hi4 CYTOCHROME P450 1A2

(Homo sapiens) 		PF00067
(p450) 		3 GLU A 168
HIS A 164
VAL A 199
 None
 0.68A 5trqB-2hi4A:
undetectable		 5trqB-2hi4A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iht CARBOXYETHYLARGININE
SYNTHASE

(Streptomyces
clavuligerus) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 GLU A 497
HIS A 508
VAL A 512
 SO4  A 603 ( 4.6A)
None
None
 0.75A 5trqB-2ihtA:
undetectable		 5trqB-2ihtA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3m PROLYL-TRNA
SYNTHETASE

(Enterococcus
faecalis) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF04073
(tRNA_edit) 		3 GLU A 454
HIS A  23
VAL A  20
 None
 0.90A 5trqB-2j3mA:
undetectable		 5trqB-2j3mA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4t ANGIOGENIN-4

(Mus musculus) 		PF00074
(RnaseA) 		3 GLU A 106
HIS A 112
VAL A 111
 None
 0.91A 5trqB-2j4tA:
undetectable		 5trqB-2j4tA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l9p UNCHARACTERIZED
PROTEIN

(Staphylococcus
epidermidis) 		PF08327
(AHSA1) 		3 GLU A  34
HIS A  38
VAL A  44
 None
 0.76A 5trqB-2l9pA:
undetectable		 5trqB-2l9pA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o8q HYPOTHETICAL PROTEIN

(Paraburkholderia
xenovorans) 		PF07883
(Cupin_2) 		3 GLU A  79
HIS A 100
VAL A  98
 None
NI  A 300 (-3.3A)
None
 0.82A 5trqB-2o8qA:
4.9		 5trqB-2o8qA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okl PEPTIDE DEFORMYLASE
2

(Bacillus cereus) 		PF01327
(Pep_deformylase) 		3 GLU A 137
HIS A  87
VAL A 139
 None
 0.88A 5trqB-2oklA:
undetectable		 5trqB-2oklA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qga ADENYLOSUCCINATE
LYASE

(Plasmodium
vivax) 		PF00206
(Lyase_1)
PF08328
(ASL_C) 		3 GLU B 145
HIS B 189
VAL B 192
 None
 0.89A 5trqB-2qgaB:
undetectable		 5trqB-2qgaB:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x6k PHOSPHOTIDYLINOSITOL
3 KINASE 59F

(Drosophila
melanogaster) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka) 		3 GLU A 570
HIS A 573
VAL A 565
 None
 0.89A 5trqB-2x6kA:
undetectable		 5trqB-2x6kA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yql PHD FINGER PROTEIN
21A

(Homo sapiens) 		PF00628
(PHD) 		3 GLU A   9
HIS A   8
VAL A  30
 None
 0.89A 5trqB-2yqlA:
undetectable		 5trqB-2yqlA:
9.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr0 HYPOTHETICAL PROTEIN
TTHA0223

(Thermus
thermophilus) 		PF08241
(Methyltransf_11) 		3 GLU A 163
HIS A 227
VAL A 226
 None
 0.87A 5trqB-2yr0A:
undetectable		 5trqB-2yr0A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yz1 TYROSINE-PROTEIN
PHOSPHATASE
NON-RECEPTOR TYPE
SUBSTRATE 1

(Mus musculus) 		PF07686
(V-set) 		3 GLU A  59
HIS A  60
VAL A  64
 None
 0.84A 5trqB-2yz1A:
undetectable		 5trqB-2yz1A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asm RIBONUCLEASE HIII

(Geobacillus
stearothermophilus) 		PF01351
(RNase_HII)
PF11858
(DUF3378) 		3 GLU A 232
HIS A 235
VAL A 238
 None
 0.78A 5trqB-3asmA:
undetectable		 5trqB-3asmA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b02 TRANSCRIPTIONAL
REGULATOR, CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		3 GLU A 144
HIS A 142
VAL A 140
 None
 0.87A 5trqB-3b02A:
undetectable		 5trqB-3b02A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 GLU A 381
HIS A 382
VAL A 389
 None
 0.81A 5trqB-3bgaA:
undetectable		 5trqB-3bgaA:
12.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgw DNAB-LIKE
REPLICATIVE HELICASE

(Bacillus phage
SPP1) 		PF00772
(DnaB)
PF03796
(DnaB_C) 		3 GLU A  16
HIS A  39
VAL A 104
 None
 0.75A 5trqB-3bgwA:
undetectable		 5trqB-3bgwA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chl ALPHA-14 GIARDIN

(Giardia
intestinalis) 		PF00191
(Annexin) 		3 GLU A 230
HIS A 237
VAL A 221
 None
 0.89A 5trqB-3chlA:
undetectable		 5trqB-3chlA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cou NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 16

(Homo sapiens) 		PF00293
(NUDIX) 		3 GLU A  80
HIS A 133
VAL A 137
 None
 0.88A 5trqB-3couA:
undetectable		 5trqB-3couA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cyj MANDELATE
RACEMASE/MUCONATE
LACTONIZING
ENZYME-LIKE PROTEIN

(Rubrobacter
xylanophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 GLU A 129
HIS A 127
VAL A 130
 None
 0.92A 5trqB-3cyjA:
undetectable		 5trqB-3cyjA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 GLU A 357
HIS A 358
VAL A 365
 None
 0.91A 5trqB-3decA:
undetectable		 5trqB-3decA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF14710
(Nitr_red_alph_N) 		3 GLU A1220
HIS A1184
VAL A1187
 None
MD1  A1245 ( 4.6A)
None
 0.86A 5trqB-3egwA:
undetectable		 5trqB-3egwA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fo5 THIOESTERASE,
ADIPOSE ASSOCIATED,
ISOFORM BFIT2

(Homo sapiens) 		PF01852
(START) 		3 GLU A 577
HIS A 433
VAL A 432
 None
 0.78A 5trqB-3fo5A:
undetectable		 5trqB-3fo5A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g0k PUTATIVE MEMBRANE
PROTEIN

(Novosphingobium
aromaticivorans) 		PF12680
(SnoaL_2) 		3 GLU A   7
HIS A  11
VAL A  75
 CA  A 130 (-2.4A)
None
None
 0.81A 5trqB-3g0kA:
undetectable		 5trqB-3g0kA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gd7 FUSION COMPLEX OF
CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR, RESIDUES
1193-1427 AND
MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK,
RESIDUES 219-371

(Escherichia
coli;
Homo sapiens) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 GLU A1548
HIS A1526
VAL A1516
 None
 0.90A 5trqB-3gd7A:
undetectable		 5trqB-3gd7A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3il2 REDOX-SENSING
TRANSCRIPTIONAL
REPRESSOR REX

(Thermus
thermophilus) 		PF02629
(CoA_binding)
PF06971
(Put_DNA-bind_N) 		3 GLU A  22
HIS A  27
VAL A  64
 None
 0.83A 5trqB-3il2A:
undetectable		 5trqB-3il2A:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtm FORMATE
DEHYDROGENASE,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 GLU A 243
HIS A 220
VAL A 238
 None
 0.82A 5trqB-3jtmA:
undetectable		 5trqB-3jtmA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3me5 CYTOSINE-SPECIFIC
METHYLTRANSFERASE

(Shigella
flexneri) 		PF00145
(DNA_methylase) 		3 GLU A  67
HIS A  70
VAL A  40
 None
 0.81A 5trqB-3me5A:
undetectable		 5trqB-3me5A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3meb ASPARTATE
AMINOTRANSFERASE

(Giardia
intestinalis) 		PF00155
(Aminotran_1_2) 		3 GLU A 116
HIS A 119
VAL A 144
 None
 0.91A 5trqB-3mebA:
undetectable		 5trqB-3mebA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2o BIOSYNTHETIC
ARGININE
DECARBOXYLASE

(Vibrio
vulnificus) 		PF02784
(Orn_Arg_deC_N) 		3 GLU A 170
HIS A 174
VAL A 176
 None
 0.84A 5trqB-3n2oA:
undetectable		 5trqB-3n2oA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nap CAPSID PROTEIN

(Triatoma virus) 		PF00073
(Rhv) 		3 GLU B 101
HIS B 219
VAL B 172
 None
 0.77A 5trqB-3napB:
undetectable		 5trqB-3napB:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nzq BIOSYNTHETIC
ARGININE
DECARBOXYLASE

(Escherichia
coli) 		PF02784
(Orn_Arg_deC_N) 		3 GLU A 187
HIS A 191
VAL A 193
 None
 0.90A 5trqB-3nzqA:
undetectable		 5trqB-3nzqA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0v ALPHA/BETA HYDROLASE
FOLD PROTEIN

(Sphaerobacter
thermophilus) 		PF12697
(Abhydrolase_6) 		3 GLU A 224
HIS A 220
VAL A 120
 None
 0.81A 5trqB-3r0vA:
undetectable		 5trqB-3r0vA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rfn BB_1WNU_001

(Pyrococcus
horikoshii) 		no annotation 3 GLU A   5
HIS A   9
VAL A  35
 None
ZN  A   1 (-3.3A)
None
 0.52A 5trqB-3rfnA:
undetectable		 5trqB-3rfnA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rlf MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK

(Escherichia
coli) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		3 GLU A 339
HIS A 317
VAL A 307
 None
 0.91A 5trqB-3rlfA:
undetectable		 5trqB-3rlfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rpd METHIONINE SYNTHASE
(B12-INDEPENDENT)

(Shewanella sp.
W3-18-1) 		PF01717
(Meth_synt_2) 		3 GLU A 165
HIS A 155
VAL A 115
 None
 0.92A 5trqB-3rpdA:
undetectable		 5trqB-3rpdA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3svt SHORT-CHAIN TYPE
DEHYDROGENASE/REDUCT
ASE

(Mycobacterium
ulcerans) 		PF13561
(adh_short_C2) 		3 GLU A 133
HIS A 129
VAL A  78
 None
 0.89A 5trqB-3svtA:
undetectable		 5trqB-3svtA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tqh QUINONE
OXIDOREDUCTASE

(Coxiella
burnetii) 		PF08240
(ADH_N)
PF13602
(ADH_zinc_N_2) 		3 GLU A 107
HIS A  38
VAL A 317
 None
 0.92A 5trqB-3tqhA:
undetectable		 5trqB-3tqhA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ulk KETOL-ACID
REDUCTOISOMERASE

(Escherichia
coli) 		PF01450
(IlvC)
PF07991
(IlvN) 		3 GLU A 141
HIS A 111
VAL A 115
 GLU  A 141 ( 0.6A)
HIS  A 111 (-1.0A)
VAL  A 115 ( 0.6A)
 0.81A 5trqB-3ulkA:
undetectable		 5trqB-3ulkA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wnv GLYOXYLATE REDUCTASE

(Paecilomyces
sp.
'thermophila') 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 GLU A 203
HIS A 183
VAL A 199
 None
 0.90A 5trqB-3wnvA:
undetectable		 5trqB-3wnvA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh9 DELTA

(Bacillus
subtilis) 		PF06144
(DNA_pol3_delta) 		3 GLU B 188
HIS B 181
VAL B 178
 None
SO4  B1340 ( 3.9A)
None
 0.86A 5trqB-3zh9B:
undetectable		 5trqB-3zh9B:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bla MALTOSE-BINDING
PERIPLASMIC PROTEIN,
SUPPRESSOR OF FUSED
HOMOLOG

(Escherichia
coli;
Homo sapiens) 		PF05076
(SUFU)
PF12470
(SUFU_C)
PF13416
(SBP_bac_8) 		3 GLU A 547
HIS A 516
VAL A 543
 None
 0.81A 5trqB-4blaA:
undetectable		 5trqB-4blaA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bpt PHENYLALANINE-4-HYDR
OXYLASE (PAH)
(PHE-4-MONOOXYGENASE
)

(Legionella
pneumophila) 		PF00351
(Biopterin_H) 		3 GLU A 117
HIS A 122
VAL A 115
 None
 0.79A 5trqB-4bptA:
undetectable		 5trqB-4bptA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bzj PROTEIN TRANSPORT
PROTEIN SEC13

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		3 GLU B  41
HIS B  43
VAL B   2
 None
 0.91A 5trqB-4bzjB:
undetectable		 5trqB-4bzjB:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d4z DEOXYHYPUSINE
HYDROXYLASE

(Homo sapiens) 		PF13646
(HEAT_2) 		3 GLU A 266
HIS A 240
VAL A 269
 None
FE  A 302 (-3.5A)
None
 0.87A 5trqB-4d4zA:
undetectable		 5trqB-4d4zA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5k PHOSPHITE
DEHYDROGENASE
(THERMOSTABLE
VARIANT)

(Pseudomonas
stutzeri) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 GLU A 196
HIS A 174
VAL A 192
 None
NAD  A 401 (-4.6A)
None
 0.92A 5trqB-4e5kA:
undetectable		 5trqB-4e5kA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6y CITRATE SYNTHASE

(Vibrio
vulnificus) 		PF00285
(Citrate_synt) 		3 GLU A 196
HIS A 200
VAL A 212
 None
 0.61A 5trqB-4e6yA:
undetectable		 5trqB-4e6yA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hbk ALDO-KETO REDUCTASE
FAMILY 1, MEMBER B4
(ALDOSE REDUCTASE)

(Schistosoma
japonicum) 		PF00248
(Aldo_ket_red) 		3 GLU A 143
HIS A  87
VAL A  88
 None
 0.89A 5trqB-4hbkA:
undetectable		 5trqB-4hbkA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kmh SUPPRESSOR OF FUSED
HOMOLOG

(Homo sapiens) 		PF05076
(SUFU)
PF12470
(SUFU_C) 		3 GLU A 207
HIS A 176
VAL A 203
 None
 0.84A 5trqB-4kmhA:
undetectable		 5trqB-4kmhA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n02 ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE

(Streptococcus
pneumoniae) 		PF01070
(FMN_dh) 		3 GLU A 180
HIS A 142
VAL A 143
 None
SO4  A 403 ( 3.8A)
None
 0.86A 5trqB-4n02A:
undetectable		 5trqB-4n02A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nec PUTATIVE
SAM-DEPENDENT
METHYLTRANSFERASE

(Streptomyces
lasaliensis) 		PF13649
(Methyltransf_25) 		3 GLU A 151
HIS A 215
VAL A 214
 None
 0.89A 5trqB-4necA:
undetectable		 5trqB-4necA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o5f TYPE III
PANTOTHENATE KINASE

(Burkholderia
thailandensis) 		PF03309
(Pan_kinase) 		3 GLU A 214
HIS A 118
VAL A 221
 None
CL  A 304 (-4.7A)
None
 0.79A 5trqB-4o5fA:
undetectable		 5trqB-4o5fA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oby ARGININE--TRNA
LIGASE

(Escherichia
coli) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		3 GLU A 147
HIS A 151
VAL A 153
 None
 0.89A 5trqB-4obyA:
undetectable		 5trqB-4obyA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdk CTP SYNTHASE

(Mycobacterium
tuberculosis) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		3 GLU A 128
HIS A 124
VAL A 105
 None
 0.60A 5trqB-4zdkA:
undetectable		 5trqB-4zdkA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwe CYTOCHROME P450
HYDROXYLASE

(Streptomyces
avermitilis) 		PF00067
(p450) 		3 GLU A  90
HIS A  91
VAL A  86
 None
HEM  A 403 (-3.9A)
None
 0.63A 5trqB-5cweA:
undetectable		 5trqB-5cweA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dcf TYROSINE RECOMBINASE
XERD,DNA TRANSLOCASE
FTSK

(Escherichia
coli) 		PF00589
(Phage_integrase)
PF09397
(Ftsk_gamma) 		3 GLU A 176
HIS A 172
VAL A 155
 None
 0.46A 5trqB-5dcfA:
undetectable		 5trqB-5dcfA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g06 EXOSOME COMPLEX
COMPONENT RRP42

(Saccharomyces
cerevisiae) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C) 		3 GLU E  72
HIS E  70
VAL E  71
 None
 0.90A 5trqB-5g06E:
undetectable		 5trqB-5g06E:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9f CRISPR SYSTEM
CASCADE SUBUNIT CASA

(Escherichia
coli) 		PF09481
(CRISPR_Cse1) 		3 GLU A 240
HIS A 238
VAL A 106
 None
 0.59A 5trqB-5h9fA:
undetectable		 5trqB-5h9fA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ho9 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		3 GLU A  73
HIS A  54
VAL A  53
 AHR  A 718 ( 3.0A)
AHR  A 719 ( 3.7A)
None
 0.93A 5trqB-5ho9A:
undetectable		 5trqB-5ho9A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihe DNA POLYMERASE II
SMALL SUBUNIT

(Pyrococcus
abyssi) 		PF00149
(Metallophos) 		3 GLU A 502
HIS A 513
VAL A 561
 D5M  A 701 (-3.6A)
None
D5M  A 701 (-3.7A)
 0.81A 5trqB-5iheA:
undetectable		 5trqB-5iheA:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5j4r WELO5

(Hapalosiphon
welwitschii) 		no annotation 3 GLU A 125
HIS A 129
VAL A 136
 None
 0.08A 5trqB-5j4rA:
44.1		 5trqB-5j4rA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjr GENOME POLYPROTEIN

(Dengue virus) 		PF00972
(Flavi_NS5)
PF01728
(FtsJ) 		3 GLU A 158
HIS A 192
VAL A 189
 None
 0.87A 5trqB-5jjrA:
undetectable		 5trqB-5jjrA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ks8 PYRUVATE CARBOXYLASE
SUBUNIT ALPHA

(Methylobacillus
flagellatus) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 GLU A  12
HIS A  41
VAL A  15
 None
 0.92A 5trqB-5ks8A:
undetectable		 5trqB-5ks8A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l7v GLYCOSIDE HYDROLASE

(Bacteroides
vulgatus) 		PF13320
(DUF4091) 		3 GLU A 219
HIS A 225
VAL A 218
 None
 0.86A 5trqB-5l7vA:
undetectable		 5trqB-5l7vA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot4 INTERAPTIN

(Legionella
pneumophila) 		no annotation 3 GLU A 622
HIS A 618
VAL A 652
 None
 0.76A 5trqB-5ot4A:
undetectable		 5trqB-5ot4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ttk AMINE OXIDASE

(Pseudomonas
putida) 		PF01593
(Amino_oxidase) 		3 GLU A 119
HIS A 115
VAL A 467
 None
 0.84A 5trqB-5ttkA:
undetectable		 5trqB-5ttkA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7m GLANDICOLINE B
O-METHYLTRANSFERASE
ROQN

(Penicillium
rubens) 		no annotation 3 GLU A 196
HIS A 200
VAL A 213
 None
 0.57A 5trqB-5w7mA:
undetectable		 5trqB-5w7mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9s GLYCOSYL HYDROLASE
FAMILY 3 PROTEIN

(Bifidobacterium
longum) 		no annotation 3 GLU A 693
HIS A 691
VAL A 674
 None
 0.88A 5trqB-5z9sA:
undetectable		 5trqB-5z9sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zdm -

(-) 		no annotation 3 GLU A 167
HIS A 126
VAL A 110
 None
 0.92A 5trqB-5zdmA:
undetectable		 5trqB-5zdmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6brd RIFAMPIN
MONOOXYGENASE

(Streptomyces
venezuelae) 		no annotation 3 GLU A 426
HIS A 431
VAL A 422
 None
 0.69A 5trqB-6brdA:
undetectable		 5trqB-6brdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c8s LOGANIC ACID
O-METHYLTRANSFERASE

(Catharanthus
roseus) 		no annotation 3 GLU A 190
HIS A 192
VAL A 193
 None
 0.86A 5trqB-6c8sA:
undetectable		 5trqB-6c8sA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c90 EXOSOME RNA HELICASE
MTR4,EXOSOME RNA
HELICASE MTR4

(Homo sapiens) 		no annotation 3 GLU A 294
HIS A 298
VAL A  99
 None
 0.36A 5trqB-6c90A:
undetectable		 5trqB-6c90A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cdd NPL4 ZINC FINGER

(Chaetomium
thermophilum) 		no annotation 3 GLU A 576
HIS A 572
VAL A 568
 None
 0.75A 5trqB-6cddA:
undetectable		 5trqB-6cddA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME RNA HELICASE
MTR4

(Homo sapiens) 		no annotation 3 GLU M 294
HIS M 298
VAL M  99
 None
 0.69A 5trqB-6d6qM:
undetectable		 5trqB-6d6qM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 3 GLU A 335
HIS A 336
VAL A 344
 None
 0.82A 5trqB-6etzA:
undetectable		 5trqB-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
ALPHA, CHLOROPLASTIC
ATP SYNTHASE DELTA
CHAIN, CHLOROPLASTIC

(Spinacia
oleracea;
Spinacia
oleracea) 		no annotation
no annotation 		3 GLU C  18
HIS d 141
VAL d  85
 None
 0.84A 5trqB-6fkhC:
undetectable		 5trqB-6fkhC:
undetectable