SIMILAR PATTERNS OF AMINO ACIDS FOR 5TOA_B_ESTB601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bgc | GRANULOCYTECOLONY-STIMULATINGFACTOR (Bos taurus) |
PF16647(GCSF) | 5 | LEU A 153ILE A 96LEU A 93HIS A 40LEU A 42 | None | 1.26A | 5toaB-1bgcA:undetectable | 5toaB-1bgcA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1brr | PROTEIN(BACTERIORHODOPSIN) (Halobacteriumsalinarum) |
PF01036(Bac_rhodopsin) | 5 | LEU A 223LEU A 93LEU A 97LEU A 152LEU A 181 | None | 1.19A | 5toaB-1brrA:undetectable | 5toaB-1brrA:24.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c41 | LUMAZINE SYNTHASE (Magnaporthegrisea) |
PF00885(DMRL_synthase) | 5 | MET A 187LEU A 114LEU A 139MET A 140LEU A 144 | None | 1.13A | 5toaB-1c41A:undetectable | 5toaB-1c41A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1csj | HEPATITIS C VIRUSRNA POLYMERASE(NS5B) (Hepacivirus C) |
PF00998(RdRP_3) | 5 | LEU A 425MET A 426ILE A 463LEU A 459HIS A 467 | None | 1.09A | 5toaB-1csjA:undetectable | 5toaB-1csjA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dl2 | CLASS IALPHA-1,2-MANNOSIDASE (Saccharomycescerevisiae) |
PF01532(Glyco_hydro_47) | 5 | MET A 301MET A 304LEU A 308ILE A 381LEU A 345 | None | 1.23A | 5toaB-1dl2A:undetectable | 5toaB-1dl2A:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gs9 | APOLIPOPROTEIN E (Homo sapiens) |
PF01442(Apolipoprotein) | 5 | GLU A 121LEU A 133LEU A 137ARG A 114LEU A 43 | None | 1.08A | 5toaB-1gs9A:2.5 | 5toaB-1gs9A:24.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwi | CYTOCHROME P450154C1 (Streptomycescoelicolor) |
PF00067(p450) | 5 | LEU A 56LEU A 55ILE A 315LEU A 314HIS A 291 | None | 1.18A | 5toaB-1gwiA:undetectable | 5toaB-1gwiA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hz4 | MALT REGULATORYPROTEIN (Escherichiacoli) |
no annotation | 5 | LEU A 135LEU A 94ILE A 100LEU A 101HIS A 62 | None | 1.20A | 5toaB-1hz4A:undetectable | 5toaB-1hz4A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i51 | CASPASE-7 SUBUNITP20 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 150LEU A 162LEU A 142 | None | 1.16A | 5toaB-1i51A:undetectable | 5toaB-1i51A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k86 | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 150LEU A 162LEU A 142 | None | 1.28A | 5toaB-1k86A:undetectable | 5toaB-1k86A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lpe | APOLIPOPROTEIN E3 (Homo sapiens) |
PF01442(Apolipoprotein) | 5 | GLU A 121LEU A 133LEU A 137ARG A 114LEU A 43 | None | 1.03A | 5toaB-1lpeA:3.0 | 5toaB-1lpeA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nkl | NK-LYSIN (Sus scrofa) |
PF05184(SapB_1) | 5 | MET A 49GLU A 24LEU A 61ILE A 69LEU A 14 | None | 1.14A | 5toaB-1nklA:undetectable | 5toaB-1nklA:17.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 11 | MET A 343LEU A 349GLU A 353LEU A 387MET A 388LEU A 391ARG A 394ILE A 424LEU A 428HIS A 524LEU A 525 | EST A 1 ( 4.0A)EST A 1 ( 4.8A)EST A 1 (-2.8A)EST A 1 (-4.0A)NoneEST A 1 ( 3.9A)EST A 1 (-3.7A)EST A 1 ( 4.5A)NoneEST A 1 (-3.8A)EST A 1 (-3.6A) | 0.40A | 5toaB-1pcgA:30.7 | 5toaB-1pcgA:59.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1pcg | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 343LEU A 402ILE A 424LEU A 428HIS A 524LEU A 525 | EST A 1 ( 4.0A)NoneEST A 1 ( 4.5A)NoneEST A 1 (-3.8A)EST A 1 (-3.6A) | 1.47A | 5toaB-1pcgA:30.7 | 5toaB-1pcgA:59.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgu | PROTEIN (NITROGENASEMOLYBDENUM IRONPROTEIN) (Klebsiellapneumoniae) |
PF00148(Oxidored_nitro) | 5 | MET A 353LEU A 397LEU A 398ILE A 362LEU A 392 | None | 1.23A | 5toaB-1qguA:undetectable | 5toaB-1qguA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qrj | HTLV-I CAPSIDPROTEIN (PrimateT-lymphotropicvirus 1) |
PF00607(Gag_p24) | 5 | LEU A 55LEU A 118LEU A 116LEU A 78LEU A 124 | None | 1.11A | 5toaB-1qrjA:undetectable | 5toaB-1qrjA:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sgv | TRNA PSEUDOURIDINESYNTHASE B (Mycobacteriumtuberculosis) |
PF01509(TruB_N)PF09142(TruB_C)PF16198(TruB_C_2) | 5 | GLU A 230LEU A 226LEU A 224ILE A 51LEU A 63 | None | 1.16A | 5toaB-1sgvA:undetectable | 5toaB-1sgvA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szn | ALPHA-GALACTOSIDASE (Trichodermareesei) |
PF16499(Melibiase_2) | 5 | LEU A 301LEU A 259ILE A 38LEU A 291LEU A 14 | None | 1.10A | 5toaB-1sznA:undetectable | 5toaB-1sznA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1szn | ALPHA-GALACTOSIDASE (Trichodermareesei) |
PF16499(Melibiase_2) | 5 | LEU A 301LEU A 294ILE A 38LEU A 291LEU A 14 | None | 1.24A | 5toaB-1sznA:undetectable | 5toaB-1sznA:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uaz | ARCHAERHODOPSIN-1 (Halorubrumchaoviator) |
PF01036(Bac_rhodopsin) | 5 | LEU A 229LEU A 99LEU A 103LEU A 158LEU A 187 | None | 1.23A | 5toaB-1uazA:undetectable | 5toaB-1uazA:23.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 7 | LEU A 327GLU A 331MET A 362LEU A 365ARG A 372LEU A 405HIS A 494 | None | 0.63A | 5toaB-1xb7A:25.9 | 5toaB-1xb7A:34.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xb7 | STEROID HORMONERECEPTOR ERR1 (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 506LEU A 327GLU A 331MET A 362LEU A 365LEU A 514 | None | 1.46A | 5toaB-1xb7A:25.9 | 5toaB-1xb7A:34.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cuy | MALONYL COA-[ACYLCARRIER PROTEIN]TRANSACYLASE (Thermusthermophilus) |
PF00698(Acyl_transf_1) | 5 | LEU A 64LEU A 110ILE A 244LEU A 205HIS A 194 | None | 1.23A | 5toaB-2cuyA:undetectable | 5toaB-2cuyA:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ex5 | DNA ENDONUCLEASEI-CEUI (Chlamydomonasmoewusii) |
PF00961(LAGLIDADG_1) | 5 | LEU A 125LEU A 123ILE A 23LEU A 20LEU A 37 | None | 1.15A | 5toaB-2ex5A:undetectable | 5toaB-2ex5A:23.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gpv | ESTROGEN-RELATEDRECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | LEU A 271GLU A 275MET A 306LEU A 309ARG A 316HIS A 434 | OHT A 500 ( 4.4A)OHT A 500 (-2.6A)OHT A 500 (-3.9A)OHT A 500 ( 4.0A)OHT A 500 (-3.8A)OHT A 500 ( 4.7A) | 0.51A | 5toaB-2gpvA:27.5 | 5toaB-2gpvA:37.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i76 | HYPOTHETICAL PROTEIN (Thermotogamaritima) |
PF10728(DUF2520) | 5 | LEU A 83LEU A 76ILE A 28LEU A 29LEU A 3 | None | 1.22A | 5toaB-2i76A:undetectable | 5toaB-2i76A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2irm | MITOGEN-ACTIVATEDPROTEIN KINASEKINASE KINASE 7INTERACTING PROTEIN1 (Anophelesgambiae) |
PF00481(PP2C) | 5 | LEU A 282MET A 283LEU A 359LEU A 306LEU A 188 | None | 1.10A | 5toaB-2irmA:undetectable | 5toaB-2irmA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjm | GLYCOSYLTRANSFERASE, GROUP 1FAMILY PROTEIN (Bacillusanthracis) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 5 | LEU A 289ILE A 202LEU A 269HIS A 203LEU A 277 | None | 1.25A | 5toaB-2jjmA:undetectable | 5toaB-2jjmA:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 5 | LEU A 166LEU A 245LEU A 246ILE A 208LEU A 204 | NoneHEM A 501 (-4.3A)NoneNoneNone | 1.27A | 5toaB-2m56A:undetectable | 5toaB-2m56A:21.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 11 | MET A 343LEU A 349GLU A 353LEU A 387MET A 388LEU A 391ARG A 394ILE A 424LEU A 428HIS A 524LEU A 525 | EST A 596 (-4.8A)EST A 596 ( 4.1A)EST A 596 (-2.7A)EST A 596 ( 4.2A)NoneEST A 596 ( 4.6A)EST A 596 (-4.0A)EST A 596 ( 4.7A)NoneEST A 596 (-4.2A)EST A 596 (-3.6A) | 0.52A | 5toaB-2ocfA:31.2 | 5toaB-2ocfA:53.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ocf | ESTROGEN RECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 6 | MET A 343LEU A 402ILE A 424LEU A 428HIS A 524LEU A 525 | EST A 596 (-4.8A)NoneEST A 596 ( 4.7A)NoneEST A 596 (-4.2A)EST A 596 (-3.6A) | 1.48A | 5toaB-2ocfA:31.2 | 5toaB-2ocfA:53.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ql7 | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 150LEU A 162LEU A 142 | None | 1.22A | 5toaB-2ql7A:undetectable | 5toaB-2ql7A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vp3 | VP39 (Vaccinia virus) |
PF01358(PARP_regulatory) | 5 | LEU A 42GLU A 46LEU A 78ILE A 102LEU A 103 | SAH A 400 (-4.7A)NoneNoneNoneNone | 0.95A | 5toaB-2vp3A:undetectable | 5toaB-2vp3A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y7j | PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM (Homo sapiens) |
PF00069(Pkinase) | 5 | MET A 134LEU A 137ILE A 268LEU A 271LEU A 226 | None | 1.23A | 5toaB-2y7jA:undetectable | 5toaB-2y7jA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ada | SARCOSINE OXIDASEBETA SUBUNIT (Corynebacteriumsp. U-96) |
PF01266(DAO) | 5 | LEU B 232LEU B 346ILE B 338LEU B 367LEU B 385 | FAD B 1 (-4.6A)NoneNoneNoneNone | 1.11A | 5toaB-3adaB:undetectable | 5toaB-3adaB:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2d | CD180 ANTIGEN (Homo sapiens) |
PF00560(LRR_1)PF13855(LRR_8) | 5 | LEU A 51LEU A 79ILE A 68LEU A 84HIS A 69 | None | 1.05A | 5toaB-3b2dA:undetectable | 5toaB-3b2dA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d1j | GLYCOGEN SYNTHASE (Escherichiacoli) |
PF00534(Glycos_transf_1)PF08323(Glyco_transf_5) | 5 | LEU A 326LEU A 311ILE A 435LEU A 431LEU A 318 | None | 1.16A | 5toaB-3d1jA:undetectable | 5toaB-3d1jA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e0f | PUTATIVEMETAL-DEPENDENTPHOSPHOESTERASE (Bifidobacteriumadolescentis) |
PF02811(PHP) | 5 | LEU A 274LEU A 270ILE A 46LEU A 32LEU A 87 | None | 1.23A | 5toaB-3e0fA:undetectable | 5toaB-3e0fA:23.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eop | THYMOCYTE NUCLEARPROTEIN 1 (Homo sapiens) |
PF01878(EVE) | 5 | LEU A 208LEU A 197ILE A 173LEU A 178LEU A 126 | None | 1.21A | 5toaB-3eopA:undetectable | 5toaB-3eopA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzs | UNCHARACTERIZED SUSDSUPERFAMILY PROTEIN (Bacteroidesfragilis) |
PF12741(SusD-like) | 5 | GLU A 464LEU A 241ARG A 244ILE A 154LEU A 198 | None | 1.13A | 5toaB-3gzsA:undetectable | 5toaB-3gzsA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i4t | DIPHTHINE SYNTHASE (Entamoebahistolytica) |
PF00590(TP_methylase) | 5 | MET A 188LEU A 236MET A 233LEU A 237LEU A 198 | None | 1.15A | 5toaB-3i4tA:undetectable | 5toaB-3i4tA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9t | V-TYPE PROTON ATPASESUBUNIT H (Saccharomycescerevisiae) |
PF03224(V-ATPase_H_N)PF11698(V-ATPase_H_C) | 5 | MET P 211LEU P 214LEU P 218LEU P 274LEU P 253 | None | 1.07A | 5toaB-3j9tP:undetectable | 5toaB-3j9tP:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k1l | FANCL (Drosophilamelanogaster) |
no annotation | 5 | LEU B 18LEU B 45ILE B 92LEU B 93HIS B 88 | None | 1.27A | 5toaB-3k1lB:undetectable | 5toaB-3k1lB:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kez | PUTATIVE SUGARBINDING PROTEIN (Bacteroidesvulgatus) |
PF07980(SusD_RagB)PF14322(SusD-like_3) | 5 | LEU A 228LEU A 406ILE A 385LEU A 382LEU A 413 | None | 1.24A | 5toaB-3kezA:undetectable | 5toaB-3kezA:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kye | ROADBLOCK/LC7DOMAIN, ROBL_LC7 (Streptomycesavermitilis) |
PF03259(Robl_LC7) | 5 | LEU A 16MET A 17LEU A 20ARG A 23LEU A 128 | None | 1.25A | 5toaB-3kyeA:undetectable | 5toaB-3kyeA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpx | DNA GYRASE, ASUBUNIT (Colwelliapsychrerythraea) |
PF00521(DNA_topoisoIV) | 5 | LEU A 203LEU A 351ILE A 502LEU A 506LEU A 356 | None | 1.26A | 5toaB-3lpxA:undetectable | 5toaB-3lpxA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n0u | PROBABLEN-GLYCOSYLASE/DNALYASE (Thermotogamaritima) |
no annotation | 5 | GLU A 35LEU A 38LEU A 107ILE A 126LEU A 119 | NoneNoneNone NA A 208 (-4.9A)None | 1.27A | 5toaB-3n0uA:undetectable | 5toaB-3n0uA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nvs | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Vibrio cholerae) |
PF00275(EPSP_synthase) | 5 | LEU A 178MET A 179ILE A 208LEU A 31HIS A 207 | None | 1.06A | 5toaB-3nvsA:undetectable | 5toaB-3nvsA:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p01 | TWO-COMPONENTRESPONSE REGULATOR (Nostoc sp. PCC7120) |
PF13185(GAF_2) | 5 | LEU A 279LEU A 308ILE A 209LEU A 176LEU A 206 | None | 1.26A | 5toaB-3p01A:undetectable | 5toaB-3p01A:22.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pyg | 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE (Mycobacteriumtuberculosis) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C) | 5 | LEU A 179LEU A 237ILE A 253LEU A 241LEU A 18 | None | 1.11A | 5toaB-3pygA:undetectable | 5toaB-3pygA:24.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r75 | ANTHRANILATE/PARA-AMINOBENZOATESYNTHASES COMPONENTI (Burkholderialata) |
PF00117(GATase)PF00425(Chorismate_bind) | 5 | MET A 490LEU A 600ILE A 535LEU A 536LEU A 515 | None | 1.18A | 5toaB-3r75A:undetectable | 5toaB-3r75A:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rhc | GLUTAREDOXIN-C5,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00462(Glutaredoxin) | 5 | GLU A 105MET A 102LEU A 103ILE A 84LEU A 99 | None | 1.15A | 5toaB-3rhcA:undetectable | 5toaB-3rhcA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rht | (GATASE1)-LIKEPROTEIN (Planctopiruslimnophila) |
PF07090(GATase1_like) | 5 | LEU A 191LEU A 82MET A 81ILE A 108LEU A 104 | None | 1.21A | 5toaB-3rhtA:undetectable | 5toaB-3rhtA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3un9 | NLR FAMILY MEMBER X1 (Homo sapiens) |
PF13516(LRR_6) | 5 | LEU A 745LEU A 746ILE A 781LEU A 773LEU A 727 | None | 1.18A | 5toaB-3un9A:undetectable | 5toaB-3un9A:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4c | ALDEHYDEDEHYDROGENASE(NADP+) (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 5 | MET A 406ILE A 421LEU A 438HIS A 422LEU A 272 | None | 1.28A | 5toaB-3v4cA:undetectable | 5toaB-3v4cA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2q | RETINOIC ACIDINDUCIBLE PROTEIN I (Anasplatyrhynchos) |
PF00270(DEAD)PF00271(Helicase_C)PF16739(CARD_2) | 5 | MET A 76LEU A 77ILE A 88LEU A 73LEU A 96 | None | 1.11A | 5toaB-4a2qA:undetectable | 5toaB-4a2qA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4af3 | AURORA KINASE B (Homo sapiens) |
PF00069(Pkinase) | 5 | MET A 181LEU A 184ILE A 304LEU A 307LEU A 266 | None | 1.06A | 5toaB-4af3A:undetectable | 5toaB-4af3A:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | LEU A 155LEU A 74LEU A 73LEU A 13LEU A 47 | None | 1.26A | 5toaB-4c7vA:undetectable | 5toaB-4c7vA:17.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cs5 | PROLIFERATING CELLNUCLEAR ANTIGEN (Litopenaeusvannamei) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | LEU A 12LEU A 11ILE A 247LEU A 221LEU A 37 | None | 1.23A | 5toaB-4cs5A:undetectable | 5toaB-4cs5A:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4w | DNA MISMATCH REPAIRPROTEIN MLH1 (Saccharomycescerevisiae) |
PF16413(Mlh1_C) | 5 | LEU A 627LEU A 649ILE A 584LEU A 586LEU A 655 | None | 1.19A | 5toaB-4e4wA:undetectable | 5toaB-4e4wA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e7w | GLYCOGEN SYNTHASEKINASE 3 (Ustilago maydis) |
PF00069(Pkinase) | 5 | MET A 143LEU A 146ILE A 298LEU A 301LEU A 231 | None | 1.12A | 5toaB-4e7wA:undetectable | 5toaB-4e7wA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4egw | MAGNESIUM TRANSPORTPROTEIN CORA (Methanocaldococcusjannaschii) |
PF01544(CorA) | 5 | LEU A 180LEU A 158LEU A 161ILE A 244LEU A 165 | NoneBU1 A 305 (-3.6A)NoneNoneNone | 1.11A | 5toaB-4egwA:undetectable | 5toaB-4egwA:22.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbz | DELTARHODOPSIN (Haloterrigenathermotolerans) |
PF01036(Bac_rhodopsin) | 5 | LEU A 223LEU A 92ILE A 178LEU A 151LEU A 180 | None | 1.06A | 5toaB-4fbzA:undetectable | 5toaB-4fbzA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fbz | DELTARHODOPSIN (Haloterrigenathermotolerans) |
PF01036(Bac_rhodopsin) | 5 | LEU A 223LEU A 92LEU A 96ILE A 178LEU A 151 | None | 1.09A | 5toaB-4fbzA:undetectable | 5toaB-4fbzA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hq1 | PROBABLE RECEPTORPROTEIN KINASE TMK1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 5 | MET A 204LEU A 180LEU A 216ILE A 225LEU A 239 | None | 1.25A | 5toaB-4hq1A:undetectable | 5toaB-4hq1A:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hzu | ENERGY-COUPLINGFACTOR TRANSPORTERTRANSMEMBRANEPROTEIN ECFTPREDICTED MEMBRANEPROTEIN (Lactobacillusbrevis) |
PF02361(CbiQ)PF07155(ECF-ribofla_trS) | 5 | LEU T 171GLU T 174MET T 205LEU T 208LEU S 39 | None | 1.09A | 5toaB-4hzuT:undetectable | 5toaB-4hzuT:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jhj | MIF4GDOMAIN-CONTAININGPROTEIN B (Danio rerio) |
PF02854(MIF4G) | 5 | GLU A 147LEU A 136ILE A 198LEU A 177HIS A 156 | None | 1.16A | 5toaB-4jhjA:undetectable | 5toaB-4jhjA:24.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jvs | PUTATIVEUNCHARACTERIZEDPROTEIN (Legionelladrancourtii) |
no annotation | 5 | LEU A 335LEU A 354ILE A 480LEU A 505LEU A 347 | None | 1.27A | 5toaB-4jvsA:undetectable | 5toaB-4jvsA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx2 | HYPOTHETICAL PROTEIN (Legionellapneumophila) |
no annotation | 5 | LEU A 168MET A 165LEU A 169LEU A 221LEU A 232 | None | 1.27A | 5toaB-4jx2A:undetectable | 5toaB-4jx2A:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kk2 | MONOTERPENE SYNTHASEFDS-5, CHLOROPLASTIC- FARNESYLDIPHOSPHATE SYNTHASE1 CHIMERA (Artemisiaspiciformis) |
PF00348(polyprenyl_synt) | 5 | LEU A 301LEU A 279LEU A 179HIS A 187LEU A 184 | None | 1.26A | 5toaB-4kk2A:2.6 | 5toaB-4kk2A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lqx | TENA/THI-4DOMAIN-CONTAININGPROTEIN (Sulfolobussolfataricus) |
PF03070(TENA_THI-4)PF16293(zf-C2H2_9) | 5 | MET A 161LEU A 159ILE A 102LEU A 98LEU A 167 | None | 1.17A | 5toaB-4lqxA:2.3 | 5toaB-4lqxA:23.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mk0 | BETA-ADRENERGICRECEPTOR KINASE 1 (Homo sapiens) |
PF00069(Pkinase)PF00169(PH)PF00615(RGS) | 5 | MET A 380LEU A 381ILE A 333LEU A 305LEU A 279 | None | 1.21A | 5toaB-4mk0A:undetectable | 5toaB-4mk0A:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkn | TRIOSEPHOSPHATEISOMERASE (Chlamydomonasreinhardtii) |
PF00121(TIM) | 5 | MET A 147LEU A 150ILE A 208LEU A 206HIS A 187 | None | 1.11A | 5toaB-4mknA:undetectable | 5toaB-4mknA:22.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4n1y | ESTROGEN RECEPTOR (Crassostreagigas) |
PF00104(Hormone_recep) | 6 | LEU A 286GLU A 290MET A 321LEU A 324ARG A 331ILE A 361 | None | 0.70A | 5toaB-4n1yA:28.3 | 5toaB-4n1yA:38.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1o | RIBONUCLEASE L (Sus scrofa) |
PF00069(Pkinase)PF06479(Ribonuc_2-5A)PF12796(Ank_2)PF13857(Ank_5) | 5 | LEU A 108LEU A 106ILE A 96HIS A 62LEU A 61 | None | 1.13A | 5toaB-4o1oA:undetectable | 5toaB-4o1oA:16.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4udb | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
PF00104(Hormone_recep) | 5 | LEU A 772MET A 807LEU A 810LEU A 814ARG A 817 | CV7 A1987 ( 4.5A)CV7 A1987 ( 3.9A)CV7 A1987 (-4.0A)CV7 A1987 ( 4.0A)CV7 A1987 (-3.7A) | 0.47A | 5toaB-4udbA:25.5 | 5toaB-4udbA:27.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1u | LYND (Lyngbyaaestuarii) |
PF02624(YcaO) | 5 | LEU A 157LEU A 182LEU A 181ILE A 291LEU A 286 | None | 1.14A | 5toaB-4v1uA:undetectable | 5toaB-4v1uA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wai | COMF OPERON PROTEIN2 (Bacillussubtilis) |
PF10719(ComFB) | 5 | MET A 10LEU A 13ARG A 16ILE A 72LEU A 73 | None | 1.27A | 5toaB-4waiA:undetectable | 5toaB-4waiA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wu0 | SIMILAR TO YTER(BACILUS SUBTILIS) (Clostridiumacetobutylicum) |
PF07470(Glyco_hydro_88) | 5 | MET A 8LEU A 29LEU A 31ILE A 17LEU A 19 | None | 1.13A | 5toaB-4wu0A:undetectable | 5toaB-4wu0A:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zvs | CASPASE-7 (Homo sapiens) |
PF00656(Peptidase_C14) | 5 | MET A 119LEU A 123ILE A 150LEU A 162LEU A 142 | None | 1.26A | 5toaB-4zvsA:undetectable | 5toaB-4zvsA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csa | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00364(Biotin_lipoyl)PF08326(ACC_central) | 5 | MET A 862LEU A 865ARG A 868ILE A 885LEU A 881 | None | 1.09A | 5toaB-5csaA:undetectable | 5toaB-5csaA:13.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csl | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF00289(Biotin_carb_N)PF00364(Biotin_lipoyl)PF01039(Carboxyl_trans)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2)PF08326(ACC_central) | 5 | MET A 862LEU A 865ARG A 868ILE A 885LEU A 881 | None | 1.10A | 5toaB-5cslA:undetectable | 5toaB-5cslA:7.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dkp | ATP-DEPENDENT CLPPROTEASE PROTEOLYTICSUBUNIT (Neisseriameningitidis) |
PF00574(CLP_protease) | 5 | LEU A 107LEU A 108ILE A 126LEU A 191HIS A 127 | None | 1.21A | 5toaB-5dkpA:undetectable | 5toaB-5dkpA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g53 | ADENOSINE RECEPTORA2A (Homo sapiens) |
PF00001(7tm_1) | 5 | LEU A 194MET A 193LEU A 192ILE A 92LEU A 96 | None | 1.12A | 5toaB-5g53A:undetectable | 5toaB-5g53A:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g53 | ADENOSINE RECEPTORA2A (Homo sapiens) |
PF00001(7tm_1) | 5 | LEU A 194MET A 193LEU A 192LEU A 96LEU A 247 | None | 1.14A | 5toaB-5g53A:undetectable | 5toaB-5g53A:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnc | AVH146 (Phytophthorasojae) |
no annotation | 5 | LEU A 528MET A 515LEU A 516LEU A 512LEU A 465 | None | 1.24A | 5toaB-5gncA:undetectable | 5toaB-5gncA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6e | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF08326(ACC_central) | 5 | MET A 862LEU A 865ARG A 868ILE A 885LEU A 881 | None | 1.13A | 5toaB-5i6eA:undetectable | 5toaB-5i6eA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jxr | CHROMATIN-REMODELINGCOMPLEX ATPASE-LIKEPROTEIN (Thermothelomycesthermophila) |
PF00176(SNF2_N)PF00271(Helicase_C) | 5 | GLU A 523ARG A 151ILE A 486LEU A 485LEU A 499 | None | 1.15A | 5toaB-5jxrA:undetectable | 5toaB-5jxrA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lc8 | ARACHIDONATE15-LIPOXYGENASE (Pseudomonasaeruginosa) |
PF00305(Lipoxygenase) | 5 | LEU A 107LEU A 181ILE A 117LEU A 139LEU A 611 | NoneNoneNoneNoneZPE A 703 ( 4.9A) | 1.17A | 5toaB-5lc8A:2.8 | 5toaB-5lc8A:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m11 | IMMUNOREACTIVE 84KDANTIGEN PG93 (Porphyromonasgingivalis) |
no annotation | 5 | GLU A 274LEU A 313ARG A 260ILE A 284LEU A 311 | None | 1.08A | 5toaB-5m11A:undetectable | 5toaB-5m11A:14.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2u | NUCLEOPROTEIN (Influenza Dvirus) |
no annotation | 5 | MET A 257LEU A 193ILE A 223LEU A 219LEU A 238 | None | 1.22A | 5toaB-5n2uA:undetectable | 5toaB-5n2uA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nux | CHROMATE REDUCTASE (Thermusscotoductus) |
no annotation | 5 | LEU A 41LEU A 40ILE A 90LEU A 86LEU A 48 | None | 1.00A | 5toaB-5nuxA:undetectable | 5toaB-5nuxA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u4h | UDP-N-ACETYLGLUCOSAMINE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 6 | LEU A 96GLU A 168LEU A 195ILE A 39LEU A 41LEU A 34 | None | 1.19A | 5toaB-5u4hA:undetectable | 5toaB-5u4hA:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u5g | 6-PHOSPHOGLUCONATEDEHYDROGENASE (Pseudomonassyringae) |
PF03446(NAD_binding_2)PF14833(NAD_binding_11) | 5 | LEU A 62LEU A 87ARG A 60HIS A 108LEU A 107 | None | 1.21A | 5toaB-5u5gA:undetectable | 5toaB-5u5gA:21.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ufs | ANCESTRALGLUCOCORTICOIDRECEPTOR2 (unidentified) |
PF00104(Hormone_recep) | 5 | MET A 29LEU A 35MET A 70LEU A 77ARG A 80 | 1TA A 301 ( 2.9A)1TA A 301 ( 3.6A)1TA A 301 ( 3.1A)1TA A 301 ( 3.4A)1TA A 301 (-3.5A) | 0.71A | 5toaB-5ufsA:26.4 | 5toaB-5ufsA:30.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uuu | BETA-ADRENERGICRECEPTOR KINASE 1 (Homo sapiens) |
PF00069(Pkinase)PF00615(RGS) | 5 | MET A 380LEU A 381ILE A 333LEU A 305LEU A 279 | None | 1.21A | 5toaB-5uuuA:undetectable | 5toaB-5uuuA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ewx | PEAK1-RELATEDKINASE-ACTIVATINGPSEUDOKINASE 1 (Rattusnorvegicus) |
no annotation | 5 | LEU A1100LEU A1099ILE A1176LEU A1174HIS A1117 | None | 1.18A | 5toaB-6ewxA:undetectable | 5toaB-6ewxA:15.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5z | UPF0434 FAMILYPROTEIN (Haloferaxvolcanii) |
no annotation | 5 | LEU C 5MET C 6LEU C 9ILE C 46LEU C 35 | NoneNoneGOL C 101 ( 4.7A)NoneGOL C 101 (-4.8A) | 1.09A | 5toaB-6f5zC:undetectable | 5toaB-6f5zC:14.81 |