SIMILAR PATTERNS OF AMINO ACIDS FOR 5TDZ_A_ADNA905_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a6c TOBACCO RINGSPOT
VIRUS CAPSID PROTEIN

(Tobacco
ringspot virus) 		PF03391
(Nepo_coat)
PF03688
(Nepo_coat_C)
PF03689
(Nepo_coat_N) 		4 THR A 139
ASP A  79
ARG A  83
ASP A  85
 None
 1.05A 5tdzA-1a6cA:
undetectable		 5tdzA-1a6cA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0a PROTEIN (FOLD
BIFUNCTIONAL
PROTEIN)

(Escherichia
coli) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		4 ARG A  66
THR A  85
ASP A  84
LEU A  82
 None
 1.14A 5tdzA-1b0aA:
undetectable		 5tdzA-1b0aA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cf7 PROTEIN
(TRANSCRIPTION
FACTOR E2F-4)

(Homo sapiens) 		PF02319
(E2F_TDP) 		4 THR A  49
ASP A  48
LEU A  45
ASP A  42
 None
 1.10A 5tdzA-1cf7A:
undetectable		 5tdzA-1cf7A:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 ARG S 437
THR S 610
ASP S 607
LEU S 605
 None
 1.15A 5tdzA-1i84S:
0.1		 5tdzA-1i84S:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m2w MANNITOL
DEHYDROGENASE

(Pseudomonas
fluorescens) 		PF01232
(Mannitol_dh)
PF08125
(Mannitol_dh_C) 		4 THR A 389
ARG A 392
LEU A 393
ASP A 396
 None
 1.14A 5tdzA-1m2wA:
0.4		 5tdzA-1m2wA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1osn THYMIDINE KINASE

(Human
alphaherpesvirus
3) 		PF00693
(Herpes_TK) 		4 ASP A  18
ARG A 130
LEU A  17
ASP A 129
 None
BVP  A 500 (-2.8A)
None
BVP  A 500 ( 4.9A)
 1.05A 5tdzA-1osnA:
undetectable		 5tdzA-1osnA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8c HYPOTHETICAL PROTEIN
MG027

(Mycoplasma
genitalium) 		PF09185
(DUF1948) 		4 ARG A  14
THR A 118
ASP A 119
LEU A 122
 IOD  A 153 ( 4.6A)
None
None
None
 1.02A 5tdzA-1q8cA:
undetectable		 5tdzA-1q8cA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8c HYPOTHETICAL PROTEIN
MG027

(Mycoplasma
genitalium) 		PF09185
(DUF1948) 		4 ARG A  14
THR A 118
ASP A 119
LEU A 123
 IOD  A 153 ( 4.6A)
None
None
None
 1.09A 5tdzA-1q8cA:
undetectable		 5tdzA-1q8cA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qc5 PROTEIN (ALPHA1
BETA1 INTEGRIN)

(Homo sapiens) 		PF00092
(VWA) 		4 THR B 418
ASP B 417
LEU B 414
ASP B 448
 None
 1.17A 5tdzA-1qc5B:
5.7		 5tdzA-1qc5B:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r3n BETA-ALANINE
SYNTHASE

(Lachancea
kluyveri) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 THR A  67
ASP A  70
ARG A  63
LEU A  64
 None
 1.17A 5tdzA-1r3nA:
undetectable		 5tdzA-1r3nA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)

(Synechococcus
elongatus) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 THR A  75
ASP A  76
ARG A  79
ASP A 106
 None
 1.00A 5tdzA-1rblA:
2.2		 5tdzA-1rblA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1u CHOLINE
O-ACETYLTRANSFERASE

(Rattus
norvegicus) 		PF00755
(Carn_acyltransf) 		4 THR A 181
ASP A 180
LEU A 174
ASP A 315
 None
 1.16A 5tdzA-1t1uA:
undetectable		 5tdzA-1t1uA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v0m ENDO-1,4-BETA-XYLANA
SE A

(Streptomyces
lividans) 		PF00331
(Glyco_hydro_10) 		4 ARG A  14
ARG A 219
LEU A 222
ASP A 253
 IMD  A1305 (-3.6A)
None
None
None
 1.20A 5tdzA-1v0mA:
2.5		 5tdzA-1v0mA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4a GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE

(Escherichia
coli) 		PF03710
(GlnE)
PF08335
(GlnD_UR_UTase) 		4 ARG A  94
ASP A 211
ARG A 221
ASP A 173
 None
 1.17A 5tdzA-1v4aA:
undetectable		 5tdzA-1v4aA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xeb HYPOTHETICAL PROTEIN
PA0115

(Pseudomonas
aeruginosa) 		PF13673
(Acetyltransf_10) 		4 THR A  49
ASP A  68
ARG A  71
LEU A  67
 None
 1.08A 5tdzA-1xebA:
undetectable		 5tdzA-1xebA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xhb POLYPEPTIDE
N-ACETYLGALACTOSAMIN
YLTRANSFERASE 1

(Mus musculus) 		PF00535
(Glycos_transf_2)
PF00652
(Ricin_B_lectin) 		4 THR A 206
ARG A 193
LEU A 208
ASP A 209
 None
None
None
MN  A 600 (-3.2A)
 1.19A 5tdzA-1xhbA:
undetectable		 5tdzA-1xhbA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yx2 AMINOMETHYLTRANSFERA
SE

(Bacillus
subtilis) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 THR A  85
ASP A  97
LEU A  98
ASP A 120
 None
 1.02A 5tdzA-1yx2A:
undetectable		 5tdzA-1yx2A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zup HYPOTHETICAL PROTEIN
TM1739

(Thermotoga
maritima) 		PF09376
(NurA) 		4 THR A 256
ARG A  80
LEU A  42
ASP A  43
 None
 1.14A 5tdzA-1zupA:
undetectable		 5tdzA-1zupA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b2x INTEGRIN ALPHA-1

(Rattus
norvegicus) 		PF00092
(VWA) 		4 THR A 232
ASP A 231
LEU A 228
ASP A 262
 None
 1.17A 5tdzA-2b2xA:
5.9		 5tdzA-2b2xA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bde CYTOSOLIC IMP-GMP
SPECIFIC
5'-NUCLEOTIDASE

(Legionella
pneumophila) 		PF05761
(5_nucleotid) 		4 ASP A 308
ARG A 311
LEU A 312
ASP A 315
 None
 1.20A 5tdzA-2bdeA:
undetectable		 5tdzA-2bdeA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2btd PTS-DEPENDENT
DIHYDROXYACETONE
KINASE

(Escherichia
coli) 		PF02734
(Dak2) 		4 THR A 195
ASP A 191
LEU A  29
ASP A  30
 None
ADP  A1211 (-2.5A)
None
MG  A1212 ( 2.3A)
 1.10A 5tdzA-2btdA:
undetectable		 5tdzA-2btdA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwa SINGLE-STRAND
BINDING PROTEIN

(Thermus
thermophilus) 		PF00436
(SSB) 		4 ASP A 140
ARG A 189
LEU A 137
ASP A 192
 None
 0.92A 5tdzA-2cwaA:
undetectable		 5tdzA-2cwaA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ew2 2-DEHYDROPANTOATE
2-REDUCTASE,
PUTATIVE

(Enterococcus
faecalis) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 THR A 273
ASP A 265
ARG A 271
LEU A 266
 None
 1.03A 5tdzA-2ew2A:
3.6		 5tdzA-2ew2A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fy2 CHOLINE
O-ACETYLTRANSFERASE

(Homo sapiens) 		PF00755
(Carn_acyltransf) 		4 THR A 171
ASP A 170
LEU A 164
ASP A 305
 None
 1.19A 5tdzA-2fy2A:
undetectable		 5tdzA-2fy2A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcu PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 3

(Arabidopsis
thaliana) 		PF00753
(Lactamase_B) 		4 ARG A  53
THR A  28
ASP A  45
LEU A  43
 None
 1.19A 5tdzA-2gcuA:
undetectable		 5tdzA-2gcuA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0b NEUREXIN-1-ALPHA

(Bos taurus) 		PF02210
(Laminin_G_2) 		4 THR A 324
ASP A 419
LEU A 296
ASP A 295
 None
 1.20A 5tdzA-2h0bA:
undetectable		 5tdzA-2h0bA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7p CELL DIVISION
PROTEIN FTSY

(Thermus
aquaticus) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 THR D 167
ASP D 168
LEU D 172
ASP D 175
 None
 0.51A 5tdzA-2j7pD:
3.6		 5tdzA-2j7pD:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lct PROTO-ONCOGENE VAV

(Homo sapiens) 		PF00017
(SH2) 		4 THR A 759
ASP A 758
LEU A 750
ASP A 752
 None
 1.12A 5tdzA-2lctA:
undetectable		 5tdzA-2lctA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m9m FANCONI
ANEMIA-ASSOCIATED
PROTEIN OF 24 KDA

(Homo sapiens) 		no annotation 4 THR A 108
ASP A 111
ARG A  73
LEU A  76
 None
 1.08A 5tdzA-2m9mA:
3.6		 5tdzA-2m9mA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oh1 ACETYLTRANSFERASE,
GNAT FAMILY

(Listeria
monocytogenes) 		no annotation 4 ARG A 107
THR A  33
ASP A  32
LEU A  29
 None
UNL  A 179 (-3.6A)
None
None
 1.10A 5tdzA-2oh1A:
undetectable		 5tdzA-2oh1A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qko POSSIBLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN

(Rhodococcus
jostii) 		PF00440
(TetR_N) 		4 ASP A 175
ARG A 178
LEU A 179
ASP A 182
 None
 0.79A 5tdzA-2qkoA:
undetectable		 5tdzA-2qkoA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rfo NUCLEOPORIN NIC96

(Saccharomyces
cerevisiae) 		PF04097
(Nic96) 		4 ARG A 724
THR A 664
ASP A 663
LEU A 661
 None
 1.12A 5tdzA-2rfoA:
undetectable		 5tdzA-2rfoA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xts CYTOCHROME

(Paracoccus
pantotrophus) 		PF13442
(Cytochrome_CBB3) 		4 THR B  61
ASP B  63
LEU B  65
ASP B  68
 None
 1.01A 5tdzA-2xtsB:
undetectable		 5tdzA-2xtsB:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y0h PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 THR A 346
ASP A 347
LEU A 320
ASP A 307
 None
 1.19A 5tdzA-2y0hA:
undetectable		 5tdzA-2y0hA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y6p 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Aquifex
aeolicus) 		PF02348
(CTP_transf_3) 		4 THR A  66
ASP A  49
LEU A  70
ASP A  69
 None
 1.05A 5tdzA-2y6pA:
undetectable		 5tdzA-2y6pA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbt PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Thermus
thermophilus) 		PF01680
(SOR_SNZ) 		4 ARG A 256
ASP A 273
LEU A 274
ASP A 246
 None
 1.17A 5tdzA-2zbtA:
undetectable		 5tdzA-2zbtA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3chl ALPHA-14 GIARDIN

(Giardia
intestinalis) 		PF00191
(Annexin) 		4 ASP A 200
ARG A 160
LEU A 204
ASP A 168
 None
 0.96A 5tdzA-3chlA:
undetectable		 5tdzA-3chlA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cir FUMARATE REDUCTASE
IRON-SULFUR SUBUNIT

(Escherichia
coli) 		PF13085
(Fer2_3)
PF13183
(Fer4_8) 		4 THR B  34
ARG B  82
LEU B  81
ASP B  83
 None
 1.11A 5tdzA-3cirB:
undetectable		 5tdzA-3cirB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cv3 GLUCURONOSYLTRANSFER
ASE GUMK

(Xanthomonas
campestris) 		no annotation 4 ARG A 154
THR A 367
ASP A 368
LEU A 371
 None
 1.08A 5tdzA-3cv3A:
1.6		 5tdzA-3cv3A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3czb PUTATIVE
TRANSGLYCOSYLASE

(Caulobacter
vibrioides) 		PF03562
(MltA)
PF06725
(3D) 		4 ASP A 333
ARG A 387
LEU A 386
ASP A 130
 None
 1.20A 5tdzA-3czbA:
undetectable		 5tdzA-3czbA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hgq HDA1 COMPLEX SUBUNIT
3

(Saccharomyces
cerevisiae) 		PF11496
(HDA2-3) 		5 THR A  45
ASP A  46
ARG A 274
LEU A 277
ASP A 275
 None
 1.38A 5tdzA-3hgqA:
undetectable		 5tdzA-3hgqA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvu HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Bacillus
anthracis) 		PF00156
(Pribosyltran) 		4 THR A  56
ARG A  55
LEU A  52
ASP A  51
 None
 1.14A 5tdzA-3hvuA:
2.8		 5tdzA-3hvuA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j04 MYOSIN-11

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		4 ARG A 437
THR A 610
ASP A 607
LEU A 605
 None
 0.80A 5tdzA-3j04A:
undetectable		 5tdzA-3j04A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lov PROTOPORPHYRINOGEN
OXIDASE

(Exiguobacterium
sibiricum) 		PF01593
(Amino_oxidase) 		4 ARG A  56
THR A 311
ARG A 404
LEU A 405
 None
None
None
FAD  A 500 ( 4.0A)
 1.16A 5tdzA-3lovA:
3.2		 5tdzA-3lovA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mqz UNCHARACTERIZED
CONSERVED PROTEIN
DUF1054

(Leptospirillum
rubarum) 		PF06335
(DUF1054) 		5 THR A 189
ASP A 188
ARG A   8
LEU A   9
ASP A  11
 CL  A 215 ( 4.3A)
None
None
None
None
 1.38A 5tdzA-3mqzA:
undetectable		 5tdzA-3mqzA:
16.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mwe ATP-CITRATE SYNTHASE

(Homo sapiens) 		PF16114
(Citrate_bind) 		5 THR A  38
ASP A  39
ARG A  42
LEU A  43
ASP A  46
 None
 0.57A 5tdzA-3mweA:
51.5		 5tdzA-3mweA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT ALPHA

(Desulfovibrio
gigas) 		PF01077
(NIR_SIR) 		4 THR A 162
ASP A 163
LEU A 102
ASP A 138
 None
None
None
SRM  A 582 (-3.8A)
 0.94A 5tdzA-3or2A:
undetectable		 5tdzA-3or2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppi 3-HYDROXYACYL-COA
DEHYDROGENASE TYPE-2

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 THR A  24
ARG A  27
LEU A  28
ASP A  31
 None
 1.19A 5tdzA-3ppiA:
6.5		 5tdzA-3ppiA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ppo GLYCINE
BETAINE/CARNITINE/CH
OLINE-BINDING
PROTEIN

(Bacillus
subtilis) 		PF04069
(OpuAC) 		4 THR A  59
ASP A  60
LEU A  61
ASP A  32
 None
 1.20A 5tdzA-3ppoA:
undetectable		 5tdzA-3ppoA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qor NUCLEAR MIGRATION
PROTEIN NUDC

(Homo sapiens) 		PF04969
(CS) 		4 ASP A 201
ARG A 208
LEU A 207
ASP A 219
 None
 1.13A 5tdzA-3qorA:
undetectable		 5tdzA-3qorA:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwu DNA LIGASE

(Aquifex
aeolicus) 		PF09414
(RNA_ligase) 		4 THR A 105
ASP A 107
ARG A 108
LEU A 109
 None
 1.14A 5tdzA-3qwuA:
undetectable		 5tdzA-3qwuA:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s25 HYPOTHETICAL
7-BLADED
BETA-PROPELLER-LIKE
PROTEIN

([Eubacterium]
rectale) 		PF16472
(DUF5050) 		4 THR A 202
ASP A 201
ARG A 185
ASP A 184
 None
 1.16A 5tdzA-3s25A:
undetectable		 5tdzA-3s25A:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wgh REDOX-SENSING
TRANSCRIPTIONAL
REPRESSOR REX

(Thermoanaerobacter
ethanolicus) 		PF02629
(CoA_binding)
PF06971
(Put_DNA-bind_N) 		4 THR A 162
ASP A 164
ARG A 168
LEU A 166
 NAI  A 301 (-3.7A)
None
None
None
 1.00A 5tdzA-3wghA:
4.5		 5tdzA-3wghA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cah DYSFERLIN

(Homo sapiens) 		PF06398
(Pex24p) 		4 THR B1001
ASP B1002
ARG B1005
LEU B1003
 None
 0.98A 5tdzA-4cahB:
undetectable		 5tdzA-4cahB:
14.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cv7 VIRULENCE ASSOCIATED
PROTEIN VAPB

(Rhodococcus
hoagii) 		PF05526
(R_equi_Vir) 		4 THR A 136
ASP A 138
ARG A 141
ASP A 145
 None
 1.18A 5tdzA-4cv7A:
undetectable		 5tdzA-4cv7A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cv7 VIRULENCE ASSOCIATED
PROTEIN VAPB

(Rhodococcus
hoagii) 		PF05526
(R_equi_Vir) 		4 THR A 136
ASP A 138
ARG A 141
LEU A 142
 None
 1.01A 5tdzA-4cv7A:
undetectable		 5tdzA-4cv7A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dq7 MEMBRANE PROTEIN
PHI6 P5

(Pseudomonas
virus phi6) 		PF10464
(Peptidase_U40) 		4 THR A 121
ASP A 123
ARG A 127
LEU A 125
 None
 1.16A 5tdzA-4dq7A:
undetectable		 5tdzA-4dq7A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fso PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 THR A  61
ASP A  60
ARG A  47
LEU A  46
 None
 1.10A 5tdzA-4fsoA:
undetectable		 5tdzA-4fsoA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1g MATRIX PROTEIN

(Avian
avulavirus 1) 		PF00661
(Matrix) 		4 ARG A 353
ASP A  47
LEU A  46
ASP A 185
 None
 1.03A 5tdzA-4g1gA:
undetectable		 5tdzA-4g1gA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gf0 GLUTATHIONE
S-TRANSFERASE

(Sulfitobacter
sp. NAS-14.1) 		PF02798
(GST_N)
PF13410
(GST_C_2) 		4 THR A  62
ASP A  61
ARG A  57
LEU A  58
 None
 0.88A 5tdzA-4gf0A:
undetectable		 5tdzA-4gf0A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4huh TAIL CONNECTOR
PROTEIN GP15

(Escherichia
virus T4) 		PF16724
(T4-gp15_tss) 		4 THR A 211
ASP A 222
LEU A 223
ASP A  19
 None
 1.17A 5tdzA-4huhA:
undetectable		 5tdzA-4huhA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i14 RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBBA

(Mycobacterium
tuberculosis) 		PF00925
(GTP_cyclohydro2)
PF00926
(DHBP_synthase) 		4 THR A   2
ARG A   3
LEU A   4
ASP A   5
 None
 0.96A 5tdzA-4i14A:
undetectable		 5tdzA-4i14A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pm4 IRON COMPLEX
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Mycobacterium
tuberculosis) 		PF01497
(Peripla_BP_2) 		4 THR A  56
ASP A  57
LEU A  84
ASP A  85
 None
 1.11A 5tdzA-4pm4A:
undetectable		 5tdzA-4pm4A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ql0 FILAMENTOUS
HEMAGGLUTININ
TRANSPORTER PROTEIN
FHAC

(Bordetella
pertussis) 		PF03865
(ShlB)
PF08479
(POTRA_2)
PF17287
(POTRA_3) 		4 THR A 279
ARG A 280
LEU A 281
ASP A 282
 None
P6G  A 609 (-2.8A)
None
PGE  A 601 ( 4.6A)
 1.07A 5tdzA-4ql0A:
undetectable		 5tdzA-4ql0A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4um8 INTEGRIN ALPHA-V

(Homo sapiens) 		PF01839
(FG-GAP)
PF08441
(Integrin_alpha2) 		4 THR A 556
ASP A 500
ARG A 509
LEU A 502
 None
 1.17A 5tdzA-4um8A:
undetectable		 5tdzA-4um8A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqg DNA POLYMERASE

(Geobacillus
stearothermophilus) 		PF00476
(DNA_pol_A) 		4 ARG A 770
ASP A 463
LEU A 465
ASP A 471
 None
 1.07A 5tdzA-4uqgA:
undetectable		 5tdzA-4uqgA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysb METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Myxococcus
xanthus) 		PF00753
(Lactamase_B) 		4 ARG A  38
THR A  15
ASP A  30
LEU A  28
 None
 1.16A 5tdzA-4ysbA:
undetectable		 5tdzA-4ysbA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yub NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Homo sapiens) 		no annotation 4 THR A  88
ASP A  89
ARG A  31
LEU A  27
 None
 1.12A 5tdzA-4yubA:
undetectable		 5tdzA-4yubA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z11 AURONE SYNTHASE

(Coreopsis
grandiflora) 		PF00264
(Tyrosinase)
PF12142
(PPO1_DWL)
PF12143
(PPO1_KFDV) 		4 ARG A 396
THR A 481
ASP A 480
LEU A 477
 None
 1.17A 5tdzA-4z11A:
undetectable		 5tdzA-4z11A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z6k ALCOHOL
DEHYDROGENASE

(Moraxella sp.
TAE123) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 THR A 274
ASP A 273
LEU A 248
ASP A 245
 None
 0.86A 5tdzA-4z6kA:
2.5		 5tdzA-4z6kA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zr5 NEPRILYSIN

(Oryctolagus
cuniculus) 		PF01431
(Peptidase_M13)
PF05649
(Peptidase_M13_N) 		4 ARG A 550
THR A 207
ASP A 208
ASP A 602
 None
 1.09A 5tdzA-4zr5A:
undetectable		 5tdzA-4zr5A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0t RIBONUCLEASE J

(Streptomyces
coelicolor) 		PF00753
(Lactamase_B)
PF07521
(RMMBL) 		4 ARG A 261
THR A 294
ASP A 296
LEU A 295
 None
 1.15A 5tdzA-5a0tA:
1.7		 5tdzA-5a0tA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ab8 GROUP 1 TRUNCATED
HEMOGLOBIN GLBN

(Mycobacterium
tuberculosis) 		PF01152
(Bac_globin) 		4 ARG A  84
THR A  49
ARG A  53
LEU A  54
 HEM  A 144 (-3.3A)
HEM  A 144 ( 2.9A)
HEM  A 144 ( 3.3A)
HEM  A 144 (-4.7A)
 1.04A 5tdzA-5ab8A:
undetectable		 5tdzA-5ab8A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ckm MANNAN-BINDING
LECTIN SERINE
PEPTIDASE 2

(Rattus
norvegicus) 		PF00431
(CUB)
PF07645
(EGF_CA) 		4 THR A 250
ARG A 247
LEU A 206
ASP A 207
 None
 0.93A 5tdzA-5ckmA:
undetectable		 5tdzA-5ckmA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e1b N-TERMINAL
XAA-PRO-LYS
N-METHYLTRANSFERASE
1

(Homo sapiens) 		PF05891
(Methyltransf_PK) 		4 ASP A 127
ARG A 158
LEU A 157
ASP A 130
 None
UNX  A 321 ( 3.9A)
None
None
 1.07A 5tdzA-5e1bA:
undetectable		 5tdzA-5e1bA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fic SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		4 ARG A 227
THR A 215
ASP A 216
ASP A 221
 None
 1.00A 5tdzA-5ficA:
undetectable		 5tdzA-5ficA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hqn SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		4 ARG A 227
THR A 215
ASP A 216
ASP A 221
 None
 1.19A 5tdzA-5hqnA:
undetectable		 5tdzA-5hqnA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy7 PUTATIVE PRE-MRNA
SPLICING PROTEIN

(Chaetomium
thermophilum) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 ARG A1027
ARG A1084
LEU A1085
ASP A1022
 None
 1.17A 5tdzA-5hy7A:
undetectable		 5tdzA-5hy7A:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idj CELL CYCLE HISTIDINE
KINASE CCKA

(Caulobacter
vibrioides) 		PF00512
(HisKA)
PF02518
(HATPase_c) 		4 THR A 472
ASP A 471
ARG A 454
LEU A 455
 None
 1.11A 5tdzA-5idjA:
undetectable		 5tdzA-5idjA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idm CELL CYCLE HISTIDINE
KINASE CCKA

(Caulobacter
vibrioides) 		PF02518
(HATPase_c) 		4 THR A 472
ASP A 471
ARG A 454
LEU A 455
 None
 0.94A 5tdzA-5idmA:
undetectable		 5tdzA-5idmA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jla PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE

(Paraburkholderia
xenovorans) 		PF13561
(adh_short_C2) 		4 ASP A  61
ARG A  41
LEU A  60
ASP A  40
 NAD  A 401 (-3.7A)
NAD  A 401 (-3.0A)
None
NAD  A 401 (-2.9A)
 1.20A 5tdzA-5jlaA:
undetectable		 5tdzA-5jlaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k31 COLLAGEN ALPHA-1(I)
CHAIN

(Homo sapiens) 		PF01410
(COLFI) 		4 THR A  15
ASP A  14
LEU A  11
ASP A   8
 None
 1.09A 5tdzA-5k31A:
undetectable		 5tdzA-5k31A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ku7 TIR-NB-LRR TYPE
RESISTANCE PROTEIN
RPV1

(Vitis
rotundifolia) 		PF01582
(TIR) 		4 ARG A  31
ARG A  92
LEU A  95
ASP A  96
 MLA  A 201 (-2.7A)
None
None
None
 1.08A 5tdzA-5ku7A:
4.6		 5tdzA-5ku7A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5och -

(-) 		no annotation 4 ASP B 525
ARG B 539
LEU B 538
ASP B 537
 None
 1.15A 5tdzA-5ochB:
undetectable		 5tdzA-5ochB:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5te1 ATP-CITRATE SYNTHASE

(Homo sapiens) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding)
PF16114
(Citrate_bind) 		5 THR A  38
ASP A  39
ARG A  42
LEU A  43
ASP A  46
 None
 0.87A 5tdzA-5te1A:
36.9		 5tdzA-5te1A:
72.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans) 		no annotation 4 ARG B  39
THR B  16
ASP B  31
LEU B  29
 None
 1.19A 5tdzA-5ve3B:
undetectable		 5tdzA-5ve3B:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vft PROTEASOME SUBUNIT
BETA TYPE-4

(Homo sapiens) 		no annotation 4 ARG T 182
ARG T  41
LEU T  27
ASP T  25
 None
 1.16A 5tdzA-5vftT:
undetectable		 5tdzA-5vftT:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vip MDCD
MDCE

(Pseudomonas
aeruginosa) 		PF01039
(Carboxyl_trans)
PF06833
(MdcE) 		4 ARG A 259
ASP B  36
LEU B  35
ASP B  57
 None
 1.11A 5tdzA-5vipA:
3.5		 5tdzA-5vipA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wjm CADHERIN-23

(Mus musculus) 		no annotation 4 ARG A1889
ASP A1892
ARG A1895
LEU A1891
 None
CA  A2006 (-3.2A)
None
None
 1.13A 5tdzA-5wjmA:
undetectable		 5tdzA-5wjmA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 4 THR A 559
ASP A 558
LEU A 556
ASP A 585
 None
 1.18A 5tdzA-5wlhA:
undetectable		 5tdzA-5wlhA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ww1 PULULLANASE

(Paenibacillus
barengoltzii) 		no annotation 4 ASP A 246
ARG A 249
LEU A 250
ASP A 251
 None
None
CL  A 716 ( 3.9A)
None
 1.14A 5tdzA-5ww1A:
undetectable		 5tdzA-5ww1A:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfa NAD-REDUCING
HYDROGENASE

(Hydrogenophilus
thermoluteolus) 		PF01257
(2Fe-2S_thioredx)
PF01512
(Complex1_51K)
PF10589
(NADH_4Fe-4S) 		4 THR A 495
ASP A 508
ARG A 511
LEU A 512
 None
 1.06A 5tdzA-5xfaA:
2.1		 5tdzA-5xfaA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aqb CHIMERA PROTEIN OF
MLK3-SH3 AND MIP
(E.C.2.7.11.25)

(Homo sapiens) 		no annotation 4 ASP A  51
ARG A  63
LEU A  62
ASP A  66
 None
 1.15A 5tdzA-6aqbA:
undetectable		 5tdzA-6aqbA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6at7 PHENYLALANINE
AMMONIA-LYASE

(Sorghum bicolor) 		no annotation 4 ARG A 108
THR A 110
ASP A 112
LEU A 116
 None
 0.97A 5tdzA-6at7A:
undetectable		 5tdzA-6at7A:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az6 GNTR FAMILY
TRANSCRIPTIONAL
REGULATOR

(Streptococcus
agalactiae) 		no annotation 4 ASP A  86
ARG A  89
LEU A  90
ASP A  93
 None
 0.39A 5tdzA-6az6A:
undetectable		 5tdzA-6az6A:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0d AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY

(Paraburkholderia
phymatum) 		no annotation 4 ASP A   9
ARG A  12
LEU A  13
ASP A  16
 EDO  A 510 (-3.0A)
EDO  A 511 ( 4.5A)
None
None
 0.94A 5tdzA-6c0dA:
undetectable		 5tdzA-6c0dA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ca7 PCT64_13C HEAVY
CHAIN

(Homo sapiens) 		no annotation 4 ARG H  71
THR H  57
ASP H  58
ASP H  35
 None
 0.99A 5tdzA-6ca7H:
undetectable		 5tdzA-6ca7H:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d5i PHOSPHOENOLPYRUVATE
CARBOXYKINASE (ATP)

(Escherichia
coli) 		no annotation 4 THR A  81
ASP A  80
ARG A  79
ASP A  76
 None
 1.18A 5tdzA-6d5iA:
undetectable		 5tdzA-6d5iA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ejf -

(-) 		no annotation 4 ASP J 266
ARG J 199
LEU J 196
ASP J 195
 None
 1.15A 5tdzA-6ejfJ:
undetectable		 5tdzA-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eon BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		no annotation 4 THR A 657
ASP A 745
LEU A 742
ASP A 741
 None
 1.04A 5tdzA-6eonA:
2.1		 5tdzA-6eonA:
20.23