SIMILAR PATTERNS OF AMINO ACIDS FOR 5PHH_A_LDPA414
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a44 | PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN (Bos taurus) |
PF01161(PBP) | 4 | ALA A 170LEU A 40TYR A 28SER A 108 | None | 0.95A | 5phhA-1a44A:0.0 | 5phhA-1a44A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c7t | BETA-N-ACETYLHEXOSAMINIDASE (Serratiamarcescens) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b)PF03173(CHB_HEX)PF03174(CHB_HEX_C) | 4 | GLU A 806ALA A 808LEU A 807SER A 321 | None | 1.03A | 5phhA-1c7tA:0.0 | 5phhA-1c7tA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgs | DNA LIGASE (Thermusfiliformis) |
PF01653(DNA_ligase_aden)PF03120(DNA_ligase_OB)PF12826(HHH_2)PF14520(HHH_5) | 4 | GLU A 549ARG A 553ALA A 552LEU A 550 | None | 1.14A | 5phhA-1dgsA:0.0 | 5phhA-1dgsA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f2e | GLUTATHIONES-TRANSFERASE (Sphingomonaspaucimobilis) |
PF00043(GST_C)PF02798(GST_N) | 4 | ALA A 154LEU A 158TYR A 181SER A 152 | None | 1.12A | 5phhA-1f2eA:undetectable | 5phhA-1f2eA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gul | GLUTATHIONETRANSFERASE A4-4 (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ALA A 156LEU A 160TYR A 184SER A 154 | None | 1.09A | 5phhA-1gulA:undetectable | 5phhA-1gulA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gw1 | MANNANENDO-1,4-BETA-MANNOSIDASE (Cellvibriojaponicus) |
PF02156(Glyco_hydro_26) | 4 | GLU A 320ARG A 208ALA A 212TYR A 285 | MAF A1427 (-2.2A) ZN A1424 (-2.2A)NoneMBF A1428 ( 3.9A) | 1.08A | 5phhA-1gw1A:undetectable | 5phhA-1gw1A:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h4r | MERLIN (Homo sapiens) |
PF00373(FERM_M)PF09379(FERM_N)PF09380(FERM_C) | 4 | GLU A 166ALA A 164LEU A 163TYR A 150 | None | 0.92A | 5phhA-1h4rA:0.0 | 5phhA-1h4rA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kn3 | PHOSPHATIDYLETHANOLAMINE BINDINGPROTEIN-2 (Mus musculus) |
PF01161(PBP) | 4 | ALA A 171LEU A 41TYR A 29SER A 109 | None | 1.06A | 5phhA-1kn3A:undetectable | 5phhA-1kn3A:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lbk | GLUTATHIONES-TRANSFERASE CLASSPI CHIMAERA (CODA) (Homo sapiens) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ALA A 151LEU A 155TYR A 179SER A 149 | None | 1.05A | 5phhA-1lbkA:undetectable | 5phhA-1lbkA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mxf | PTERIDINE REDUCTASE2 (Trypanosomacruzi) |
PF13561(adh_short_C2) | 4 | GLU A 131ALA A 130LEU A 132TYR A 106 | NDP A1277 (-4.3A)NoneNoneNone | 0.97A | 5phhA-1mxfA:undetectable | 5phhA-1mxfA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ogo | DEXTRANASE (Talaromycesminioluteus) |
PF03718(Glyco_hydro_49)PF17433(Glyco_hydro_49N) | 4 | GLU X 299ALA X 344TYR X 275SER X 60 | None | 1.13A | 5phhA-1ogoX:undetectable | 5phhA-1ogoX:20.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sb3 | 4-HYDROXYBENZOYL-COAREDUCTASE ALPHASUBUNIT (Thaueraaromatica) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | GLU A 192ARG A 248ALA A 195LEU A 193 | None | 1.16A | 5phhA-1sb3A:undetectable | 5phhA-1sb3A:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uyv | ACETYL-COACARBOXYLASE (Saccharomycescerevisiae) |
PF01039(Carboxyl_trans) | 4 | ALA A1737LEU A1739TYR A1620SER A1732 | None | 1.15A | 5phhA-1uyvA:undetectable | 5phhA-1uyvA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v9p | DNA LIGASE (Thermusfiliformis) |
PF01653(DNA_ligase_aden)PF03120(DNA_ligase_OB)PF12826(HHH_2)PF14520(HHH_5) | 4 | GLU A 552ARG A 556ALA A 555LEU A 553 | None | 1.14A | 5phhA-1v9pA:undetectable | 5phhA-1v9pA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yj8 | GLYCEROL-3-PHOSPHATEDEHYDROGENASE (Plasmodiumfalciparum) |
PF01210(NAD_Gly3P_dh_N)PF07479(NAD_Gly3P_dh_C) | 4 | GLU A 117ALA A 121LEU A 120TYR A 157 | None | 0.99A | 5phhA-1yj8A:undetectable | 5phhA-1yj8A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yxa | SERINE (OR CYSTEINE)PROTEINASEINHIBITOR, CLADE A,MEMBER 3N (Mus musculus) |
PF00079(Serpin) | 4 | GLU A 286ALA A 287LEU A 289TYR A 59 | None | 1.14A | 5phhA-1yxaA:undetectable | 5phhA-1yxaA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a3k | PROTEIN TYROSINEPHOSPHATASE,NON-RECEPTOR TYPE 7,ISOFORM 1 (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | GLU A 273ALA A 272LEU A 270TYR A 231 | None | 0.79A | 5phhA-2a3kA:undetectable | 5phhA-2a3kA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb4 | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
no annotation | 4 | GLU A 154ARG A 170TYR A 148SER A 239 | None | 1.02A | 5phhA-2cb4A:undetectable | 5phhA-2cb4A:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cc1 | BETA-LACTAMASE (Mycolicibacteriumfortuitum) |
PF13354(Beta-lactamase2) | 4 | ARG A 153ALA A 185TYR A 75SER A 181 | None | 1.15A | 5phhA-2cc1A:undetectable | 5phhA-2cc1A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cit | ENDOGLUCANASE H (Ruminiclostridiumthermocellum) |
PF02156(Glyco_hydro_26) | 4 | GLU A 222ARG A 105ALA A 109TYR A 185 | G2F A1283 (-1.8A)NoneNoneG2F A1283 (-3.8A) | 1.09A | 5phhA-2citA:undetectable | 5phhA-2citA:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e6k | TRANSKETOLASE (Thermusthermophilus) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | GLU A 140ALA A 139LEU A 137TYR A 422 | None | 1.10A | 5phhA-2e6kA:undetectable | 5phhA-2e6kA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gsr | CLASS PI GSTGLUTATHIONES-TRANSFERASE (Sus scrofa) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ALA A 149LEU A 153TYR A 177SER A 147 | None | 1.04A | 5phhA-2gsrA:undetectable | 5phhA-2gsrA:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hk7 | SHIKIMATEDEHYDROGENASE (Aquifexaeolicus) |
PF01488(Shikimate_DH)PF08501(Shikimate_dh_N) | 4 | ARG A 268LEU A 240TYR A 257SER A 113 | None | 0.95A | 5phhA-2hk7A:undetectable | 5phhA-2hk7A:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hwx | TELOMERASE-BINDINGPROTEIN EST1A (Homo sapiens) |
PF13638(PIN_4) | 4 | GLU A1334ALA A1327LEU A1328TYR A1363 | None | 0.97A | 5phhA-2hwxA:undetectable | 5phhA-2hwxA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iee | PROBABLE ABCTRANSPORTEREXTRACELLULAR-BINDING PROTEIN YCKB (Bacillussubtilis) |
PF00497(SBP_bac_3) | 4 | GLU A 50ALA A 87LEU A 211TYR A 107 | None | 1.10A | 5phhA-2ieeA:undetectable | 5phhA-2ieeA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iqx | PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN1 (Rattusnorvegicus) |
PF01161(PBP) | 4 | ALA A 171LEU A 41TYR A 29SER A 109 | None | 1.07A | 5phhA-2iqxA:undetectable | 5phhA-2iqxA:17.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pk7 | UNCHARACTERIZEDPROTEIN (Pseudomonasprotegens) |
PF03966(Trm112p) | 4 | GLU A 49ARG A 39ALA A 50LEU A 46 | None | 1.15A | 5phhA-2pk7A:undetectable | 5phhA-2pk7A:9.32 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pxj | JMJCDOMAIN-CONTAININGHISTONEDEMETHYLATIONPROTEIN 3A (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN) | 4 | GLU A 220ALA A 236LEU A 238TYR A 275 | None | 0.24A | 5phhA-2pxjA:44.8 | 5phhA-2pxjA:62.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qgz | PUTATIVE PRIMOSOMECOMPONENT (Streptococcuspyogenes) |
PF01695(IstB_IS21) | 4 | GLU A 263ARG A 286ALA A 260LEU A 262 | None | 1.13A | 5phhA-2qgzA:undetectable | 5phhA-2qgzA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ras | TRANSCRIPTIONALREGULATOR, TETRFAMILY (Novosphingobiumaromaticivorans) |
PF00440(TetR_N) | 4 | GLU A 181ARG A 99LEU A 184TYR A 88 | None | 1.07A | 5phhA-2rasA:undetectable | 5phhA-2rasA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vg2 | UNDECAPRENYLPYROPHOSPHATESYNTHETASE (Mycobacteriumtuberculosis) |
PF01255(Prenyltransf) | 4 | GLU A 173ARG A 147ALA A 175LEU A 174 | None | 1.11A | 5phhA-2vg2A:undetectable | 5phhA-2vg2A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk4 | PYRUVATEDECARBOXYLASE (Kluyveromyceslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ALA A 287LEU A 289TYR A 299SER A 284 | None | 1.14A | 5phhA-2vk4A:undetectable | 5phhA-2vk4A:20.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2w2i | 2-OXOGLUTARATEOXYGENASE (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN) | 4 | GLU A 221ALA A 237LEU A 239TYR A 276 | None | 0.53A | 5phhA-2w2iA:42.6 | 5phhA-2w2iA:83.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3x | CALE7 (Micromonosporaechinospora) |
PF13279(4HBT_2) | 4 | GLU A 51ARG A 118ALA A 54LEU A 52 | None | 1.02A | 5phhA-2w3xA:undetectable | 5phhA-2w3xA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1c | ACYL-COENZYME (Penicilliumchrysogenum) |
PF03417(AAT) | 4 | GLU A 148ALA A 149LEU A 130SER A 28 | None | 1.02A | 5phhA-2x1cA:undetectable | 5phhA-2x1cA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y9j | PROTEIN PRGH (Salmonellaenterica) |
PF09480(PrgH) | 4 | GLU A 304ALA A 305LEU A 307TYR A 314 | None | 1.06A | 5phhA-2y9jA:undetectable | 5phhA-2y9jA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cb5 | FACT COMPLEX SUBUNITSPT16 (Schizosaccharomycespombe) |
PF00557(Peptidase_M24)PF14826(FACT-Spt16_Nlob) | 4 | GLU A 363ALA A 170LEU A 173SER A 368 | None | 1.12A | 5phhA-3cb5A:undetectable | 5phhA-3cb5A:21.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ccy | PUTATIVE TETR-FAMILYTRANSCRIPTIONALREGULATOR (Bordetellaparapertussis) |
PF00440(TetR_N) | 4 | ALA A 57LEU A 59TYR A 29SER A 54 | None | 1.07A | 5phhA-3ccyA:undetectable | 5phhA-3ccyA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eaf | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (Aeropyrumpernix) |
PF13458(Peripla_BP_6) | 4 | GLU A 130ALA A 150LEU A 152SER A 198 | None | 1.08A | 5phhA-3eafA:undetectable | 5phhA-3eafA:22.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lv8 | THYMIDYLATE KINASE (Vibrio cholerae) |
PF02223(Thymidylate_kin) | 4 | GLU A 12ALA A 14LEU A 11TYR A 106 | TYD A 215 (-2.8A)ADP A 213 (-4.2A)NoneTYD A 215 ( 3.8A) | 1.11A | 5phhA-3lv8A:undetectable | 5phhA-3lv8A:27.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mdu | N-FORMIMINO-L-GLUTAMATE IMINOHYDROLASE (Pseudomonasaeruginosa) |
PF01979(Amidohydro_1) | 4 | GLU A 118ALA A 117LEU A 152TYR A 105 | None | 1.15A | 5phhA-3mduA:undetectable | 5phhA-3mduA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nap | CAPSID PROTEIN (Triatoma virus) |
PF00073(Rhv) | 4 | ARG B 120ALA B 254LEU B 206TYR B 204 | None | 0.66A | 5phhA-3napB:undetectable | 5phhA-3napB:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o76 | GLUTATHIONES-TRANSFERASE P 1 (Mus musculus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | ALA A 151LEU A 155TYR A 179SER A 149 | None | 1.06A | 5phhA-3o76A:undetectable | 5phhA-3o76A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oka | GDP-MANNOSE-DEPENDENTALPHA-(1-6)-PHOSPHATIDYLINOSITOLMONOMANNOSIDEMANNOSYLTRANSFERASE (Corynebacteriumglutamicum) |
PF00534(Glycos_transf_1)PF13439(Glyco_transf_4) | 4 | GLU A 290ARG A 210TYR A 296SER A 205 | GDD A 701 ( 4.2A)SO4 A 601 ( 4.1A)NoneGDD A 701 ( 4.1A) | 1.11A | 5phhA-3okaA:undetectable | 5phhA-3okaA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p4s | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Escherichiacoli) |
PF00890(FAD_binding_2)PF02910(Succ_DH_flav_C) | 4 | ARG A 390ALA A 397LEU A 399SER A 52 | FAD A 601 ( 3.2A)NoneFAD A 601 (-4.1A)None | 1.12A | 5phhA-3p4sA:undetectable | 5phhA-3p4sA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p5m | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteriumavium) |
PF00378(ECH_1) | 4 | ARG A 57ALA A 58TYR A 120SER A 61 | None | 1.16A | 5phhA-3p5mA:undetectable | 5phhA-3p5mA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q0c | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-9 SPECIFICSUVH5 (Arabidopsisthaliana) |
no annotation | 4 | ARG X 470LEU X 426TYR X 492SER X 423 | None | 1.11A | 5phhA-3q0cX:undetectable | 5phhA-3q0cX:18.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvm | OLEI00960 (Oleispiraantarctica) |
PF00561(Abhydrolase_1) | 4 | GLU A 81ALA A 84LEU A 80TYR A 209 | None | 1.13A | 5phhA-3qvmA:undetectable | 5phhA-3qvmA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uar | GLUTATHIONES-TRANSFERASE (Methylococcuscapsulatus) |
PF00043(GST_C)PF02798(GST_N) | 4 | ALA A 155LEU A 159TYR A 182SER A 153 | None | 1.15A | 5phhA-3uarA:undetectable | 5phhA-3uarA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vil | BETA-GLUCOSIDASE (Neotermeskoshunensis) |
PF00232(Glyco_hydro_1) | 4 | GLU A 402ARG A 103TYR A 337SER A 193 | SA0 A 507 (-2.4A)NoneSA0 A 507 (-4.1A)SA0 A 507 (-3.5A) | 1.00A | 5phhA-3vilA:undetectable | 5phhA-3vilA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a01 | PROTONPYROPHOSPHATASE (Vigna radiata) |
PF03030(H_PPase) | 4 | GLU A 301ALA A 745LEU A 743SER A 552 | None | 1.03A | 5phhA-4a01A:undetectable | 5phhA-4a01A:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aq2 | HOMOGENTISATE1,2-DIOXYGENASE (Pseudomonasputida) |
PF04209(HgmA) | 4 | GLU A 150ARG A 60ALA A 204SER A 299 | None | 1.08A | 5phhA-4aq2A:3.1 | 5phhA-4aq2A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bmv | SHORT-CHAINDEHYDROGENASE (Sphingobiumyanoikuyae) |
PF00106(adh_short) | 4 | GLU A 73ARG A 77ALA A 121LEU A 119 | None | 1.03A | 5phhA-4bmvA:undetectable | 5phhA-4bmvA:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cca | SYNTAXIN-BINDINGPROTEIN 2 (Homo sapiens) |
PF00995(Sec1) | 4 | ALA A 149LEU A 147TYR A 537SER A 152 | None | 0.99A | 5phhA-4ccaA:undetectable | 5phhA-4ccaA:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cns | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | GLU A 230ALA A 233LEU A 231SER A 259 | EDO A1490 (-4.5A)EDO A1490 (-3.6A)NoneEDO A1490 (-3.2A) | 1.04A | 5phhA-4cnsA:undetectable | 5phhA-4cnsA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cnt | DIHYDROPYRIMIDINASE-LIKE 3 (Homo sapiens) |
PF01979(Amidohydro_1) | 4 | GLU A 230ALA A 233LEU A 231SER A 259 | None | 0.99A | 5phhA-4cntA:undetectable | 5phhA-4cntA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dxw | ION TRANSPORTPROTEIN (alphaproteobacteriumHIMB114) |
PF00520(Ion_trans) | 4 | ALA A 152LEU A 154TYR A 199SER A 169 | None | 1.09A | 5phhA-4dxwA:undetectable | 5phhA-4dxwA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e3e | MAOC DOMAIN PROTEINDEHYDRATASE (Chloroflexusaurantiacus) |
PF01575(MaoC_dehydratas) | 4 | ALA A 267LEU A 266TYR A 200SER A 193 | None | 0.89A | 5phhA-4e3eA:undetectable | 5phhA-4e3eA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1k | TRIOSEPHOSPHATEISOMERASE (Burkholderiathailandensis) |
PF00121(TIM) | 4 | GLU A 162ARG A 118ALA A 122LEU A 121 | EDO A 304 (-4.2A)EDO A 304 (-3.6A)EDO A 304 (-4.1A)EDO A 304 (-4.1A) | 1.15A | 5phhA-4g1kA:undetectable | 5phhA-4g1kA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gci | GLUTATHIONES-TRANSFERASE (Yersinia pestis) |
PF00043(GST_C)PF02798(GST_N) | 4 | ALA A 155LEU A 159TYR A 182SER A 153 | None | 1.07A | 5phhA-4gciA:undetectable | 5phhA-4gciA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gdj | NEURAMINIDASE (Influenza Avirus) |
PF00064(Neur) | 4 | GLU A 356ALA A 360LEU A 354TYR A 281 | None | 0.86A | 5phhA-4gdjA:undetectable | 5phhA-4gdjA:20.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4hoo | LYSINE-SPECIFICDEMETHYLASE 4D (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN) | 6 | GLU A 224ARG A 228ALA A 240LEU A 242TYR A 279SER A 308 | None | 0.66A | 5phhA-4hooA:45.2 | 5phhA-4hooA:99.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i6m | ACTIN-LIKE PROTEINARP9 (Saccharomycescerevisiae) |
PF00022(Actin) | 4 | GLU B 347ALA B 348LEU B 350SER B 223 | None | 1.04A | 5phhA-4i6mB:undetectable | 5phhA-4i6mB:19.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j3c | RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE E (Sinorhizobiummeliloti) |
PF04452(Methyltrans_RNA) | 4 | GLU A 154ALA A 203LEU A 207SER A 201 | None | 1.13A | 5phhA-4j3cA:undetectable | 5phhA-4j3cA:25.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbb | PUTATIVE GLUTATHIONES-TRANSFERASE (Klebsiellapneumoniae) |
PF13417(GST_N_3)PF14834(GST_C_4) | 4 | ALA A 167LEU A 171TYR A 192SER A 165 | None | 1.15A | 5phhA-4jbbA:undetectable | 5phhA-4jbbA:26.58 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lxl | LYSINE-SPECIFICDEMETHYLASE 4B (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN) | 4 | GLU A 221ALA A 237LEU A 239TYR A 276 | None | 0.22A | 5phhA-4lxlA:45.5 | 5phhA-4lxlA:69.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn1 | TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 4 | GLU A 89ARG A 168ALA A 169LEU A 171 | None | 1.15A | 5phhA-4nn1A:undetectable | 5phhA-4nn1A:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q5q | GLUTATHIONES-TRANSFERASE (Dermatophagoidespteronyssinus) |
PF02798(GST_N)PF14497(GST_C_3) | 4 | GLU A 102ALA A 76LEU A 78TYR A 156 | None | 1.16A | 5phhA-4q5qA:undetectable | 5phhA-4q5qA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rg8 | EXONUCLEASE I (Methylocaldumszegediense) |
PF00929(RNase_T)PF08411(Exonuc_X-T_C) | 4 | ALA A 164LEU A 162TYR A 98SER A 159 | None | 1.01A | 5phhA-4rg8A:undetectable | 5phhA-4rg8A:20.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4usr | MONOOXYGENASE (Pseudomonasstutzeri) |
PF13738(Pyr_redox_3) | 4 | GLU A 182ALA A 181LEU A 183TYR A 156 | None | 1.03A | 5phhA-4usrA:undetectable | 5phhA-4usrA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uss | GLUTATHIONYLHYDROQUINONEREDUCTASE (Populustrichocarpa) |
PF13409(GST_N_2)PF13410(GST_C_2) | 4 | ALA A 235LEU A 239TYR A 270SER A 233 | None | 1.11A | 5phhA-4ussA:undetectable | 5phhA-4ussA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wqm | TOLUENE-4-MONOOXYGENASE ELECTRONTRANSFER COMPONENT (Pseudomonasmendocina) |
PF00111(Fer2)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 4 | GLU A 239ALA A 240LEU A 242TYR A 272 | None | 1.12A | 5phhA-4wqmA:undetectable | 5phhA-4wqmA:22.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xdo | LYSINE-SPECIFICDEMETHYLASE 4C (Homo sapiens) |
PF02373(JmjC)PF02375(JmjN) | 4 | GLU A 222ALA A 238LEU A 240TYR A 277 | None | 0.19A | 5phhA-4xdoA:44.9 | 5phhA-4xdoA:64.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yk2 | BARTONELLA EFFECTORPROTEIN (BEP)SUBSTRATE OF VIRBT4SS (Bartonellaclarridgeiae) |
no annotation | 4 | GLU A 92ARG A 96LEU A 113TYR A 170 | None | 0.77A | 5phhA-4yk2A:undetectable | 5phhA-4yk2A:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z38 | MLNA (Bacillusvelezensis) |
no annotation | 4 | GLU A 411ALA A 436LEU A 438TYR A 431 | None | 1.15A | 5phhA-4z38A:undetectable | 5phhA-4z38A:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zo6 | LIN1840 PROTEIN (Listeriainnocua) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | ALA A 400LEU A 399TYR A 439SER A 436 | None | 1.14A | 5phhA-4zo6A:undetectable | 5phhA-4zo6A:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zws | RECOMBINATIONPROTEIN UVSY (Escherichiavirus T4) |
PF11056(UvsY) | 4 | GLU A 24ARG A 120ALA A 25LEU A 21 | None | 1.13A | 5phhA-4zwsA:undetectable | 5phhA-4zwsA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zwt | RECOMBINATIONPROTEIN UVSY (Escherichiavirus T4) |
PF11056(UvsY) | 4 | GLU A 24ARG A 120ALA A 25LEU A 21 | None | 1.10A | 5phhA-4zwtA:undetectable | 5phhA-4zwtA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aee | ALPHA-GLUCOSIDASEYIHQ (Escherichiacoli) |
PF01055(Glyco_hydro_31) | 4 | GLU A 227ALA A 241LEU A 242TYR A 194 | None | 1.16A | 5phhA-5aeeA:undetectable | 5phhA-5aeeA:20.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cr4 | SLEEPING BEAUTYTRANSPOSASE, SB100X (syntheticconstruct) |
PF01498(HTH_Tnp_Tc3_2)PF13358(DDE_3) | 4 | GLU A 174ALA A 173LEU A 171TYR A 205 | None | 0.79A | 5phhA-5cr4A:undetectable | 5phhA-5cr4A:18.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e4v | NUCLEOPROTEIN,PHOSPHOPROTEIN (Measlesmorbillivirus) |
PF00973(Paramyxo_ncap)PF13825(Paramyxo_PNT) | 4 | GLU A 173ARG A 176LEU A 174TYR A 241 | None | 1.12A | 5phhA-5e4vA:undetectable | 5phhA-5e4vA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey9 | LONG-CHAIN-FATTY-ACID--AMP LIGASE FADD32 (Mycobacteriummarinum) |
PF00501(AMP-binding) | 4 | GLU A 265ARG A 221ALA A 267LEU A 266 | None | 1.02A | 5phhA-5ey9A:undetectable | 5phhA-5ey9A:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtm | INTERFERON-INDUCEDGTP-BINDING PROTEINMX1 (Homo sapiens) |
PF00350(Dynamin_N)PF01031(Dynamin_M)PF02212(GED) | 4 | GLU A 65ARG A 208ALA A 72LEU A 70 | None | 1.12A | 5phhA-5gtmA:undetectable | 5phhA-5gtmA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i51 | TRANSKETOLASE (Scheffersomycesstipitis) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | GLU A 326ARG A 329ALA A 325LEU A 327TYR A 137 | None | 1.39A | 5phhA-5i51A:undetectable | 5phhA-5i51A:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6g | ACETYL-COACARBOXYLASE-LIKEPROTEIN,ACETYL-COACARBOXYLASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF01039(Carboxyl_trans)PF08326(ACC_central) | 4 | ALA A1777LEU A1779TYR A1665SER A1772 | None | 1.12A | 5phhA-5i6gA:undetectable | 5phhA-5i6gA:16.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6h | ACETYL-COACARBOXYLASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF01039(Carboxyl_trans)PF08326(ACC_central) | 4 | ALA A1777LEU A1779TYR A1665SER A1772 | None | 1.10A | 5phhA-5i6hA:undetectable | 5phhA-5i6hA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i6i | ACETYL-COACARBOXYLASE-LIKEPROTEIN,ACETYL-COACARBOXYLASE-LIKEPROTEIN,ACETYL-COACARBOXYLASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF01039(Carboxyl_trans)PF08326(ACC_central) | 4 | ALA A1777LEU A1779TYR A1665SER A1772 | None | 1.10A | 5phhA-5i6iA:undetectable | 5phhA-5i6iA:9.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k97 | FLAP ENDONUCLEASE 1 (Homo sapiens) |
PF00752(XPG_N)PF00867(XPG_I) | 4 | GLU A 96ARG A 103ALA A 98LEU A 97 | None | 1.03A | 5phhA-5k97A:undetectable | 5phhA-5k97A:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kk5 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Acidaminococcussp. BV3L6) |
no annotation | 4 | GLU A 98ALA A 78LEU A 76TYR A 102 | None | 0.87A | 5phhA-5kk5A:undetectable | 5phhA-5kk5A:14.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz6 | SEPARASE (Caenorhabditiselegans) |
PF03568(Peptidase_C50) | 4 | GLU 1 258ALA 1 259LEU 1 261SER 1 229 | None | 1.05A | 5phhA-5mz61:undetectable | 5phhA-5mz61:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n1q | METHYL-COENZYME MREDUCTASE III FROMMETHANOTHERMOCOCCUSTHERMOLITHOTROPHICUSSUBUNIT GAMMA (Methanothermococcusthermolithotrophicus) |
PF02240(MCR_gamma) | 4 | ARG C 19ALA C 11LEU C 234TYR C 221 | None | 1.12A | 5phhA-5n1qC:undetectable | 5phhA-5n1qC:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ng6 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Francisellatularensis) |
no annotation | 4 | GLU A 213ALA A 216LEU A 212TYR A 83 | None | 1.14A | 5phhA-5ng6A:undetectable | 5phhA-5ng6A:13.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nny | WIPB (Legionellapneumophila) |
no annotation | 4 | GLU A 119LEU A 120TYR A 208SER A 149 | None | 0.99A | 5phhA-5nnyA:undetectable | 5phhA-5nnyA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tvd | TM16 (Trichuris muris) |
PF01161(PBP) | 4 | ALA A 174LEU A 45TYR A 33SER A 111 | None | 0.94A | 5phhA-5tvdA:undetectable | 5phhA-5tvdA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uak | CYSTIC FIBROSISTRANSMEMBRANECONDUCTANCEREGULATOR (Homo sapiens) |
PF00005(ABC_tran)PF00664(ABC_membrane)PF14396(CFTR_R) | 4 | ARG A 933ALA A 928LEU A 926TYR A 919 | None | 0.88A | 5phhA-5uakA:undetectable | 5phhA-5uakA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ug4 | SPERMIDINEN(1)-ACETYLTRANSFERASE (Vibrio cholerae) |
PF13302(Acetyltransf_3) | 4 | ARG A 56ALA A 9LEU A 10TYR A 46 | None | 1.07A | 5phhA-5ug4A:undetectable | 5phhA-5ug4A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wc1 | MEIOTIC SPINDLEFORMATION PROTEINMEI-1 (Caenorhabditiselegans) |
PF00004(AAA) | 4 | GLU A 436ALA A 435LEU A 433TYR A 416 | None | 0.92A | 5phhA-5wc1A:undetectable | 5phhA-5wc1A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3s | - (-) |
no annotation | 4 | GLU A 970ARG A 947ALA A 973LEU A 971 | None | 1.15A | 5phhA-5y3sA:undetectable | 5phhA-5y3sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yy3 | - (-) |
no annotation | 4 | ARG A 214ALA A 525TYR A 457SER A 522 | None | 1.13A | 5phhA-5yy3A:undetectable | 5phhA-5yy3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dxo | BLDNRNA POLYMERASEECF-SUBFAMILY SIGMAFACTOR (Streptomycesvenezuelae) |
no annotation | 4 | GLU A 41ARG A 123LEU D 58TYR A 27 | None | 1.09A | 5phhA-6dxoA:undetectable | 5phhA-6dxoA:14.01 |