SIMILAR PATTERNS OF AMINO ACIDS FOR 5OV9_B_CVIB602_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		5 ASP A  74
THR A  75
LEU A  76
TYR A  77
TYR A 337
 None
 1.13A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		5 ASP A  74
THR A  75
TYR A  77
THR A  83
TYR A 337
 None
 1.25A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		5 TYR A  72
ASP A  74
THR A  75
LEU A  76
TYR A  77
 None
 0.97A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		5 TYR A  72
ASP A  74
THR A  75
TYR A  77
THR A  83
 None
 0.96A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 TYR A  72
ASP A  74
THR A  83
VAL A 340
 None
 1.02A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 TYR A  72
THR A  83
VAL A 340
TYR A 341
 None
 0.60A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1b41 ACETYLCHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		4 TYR A  72
TYR A  77
THR A  83
TYR A 341
 None
 0.87A 5ov9B-1b41A:
63.2		 5ov9B-1b41A:
88.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bqc PROTEIN
(BETA-MANNANASE)

(Thermobifida
fusca) 		PF00150
(Cellulase) 		4 TYR A 210
ASP A 170
THR A 174
VAL A 182
 None
 1.28A 5ov9B-1bqcA:
2.5		 5ov9B-1bqcA:
21.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 ASP A  74
THR A  75
LEU A  76
TYR A  77
 None
 0.70A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 ASP A  74
THR A  75
LEU A  76
TYR A 337
 None
 0.98A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 ASP A  74
THR A  75
TYR A  77
THR A  83
 None
 0.46A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1c2o ACETYLCHOLINESTERASE

(Electrophorus
electricus) 		PF00135
(COesterase) 		4 TYR A  72
ASP A  74
THR A  75
LEU A  76
 None
 0.60A 5ov9B-1c2oA:
64.0		 5ov9B-1c2oA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3x PENTOSYLTRANSFERASE

(Cellulomonas
sp.) 		PF01048
(PNP_UDP_1) 		4 THR A 133
LEU A 132
VAL A 174
TYR A 175
 None
 1.21A 5ov9B-1c3xA:
1.8		 5ov9B-1c3xA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3x PENTOSYLTRANSFERASE

(Cellulomonas
sp.) 		PF01048
(PNP_UDP_1) 		4 THR A 133
THR A 224
VAL A 174
TYR A 175
 None
 1.11A 5ov9B-1c3xA:
1.8		 5ov9B-1c3xA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d5y ROB TRANSCRIPTION
FACTOR

(Escherichia
coli) 		PF06445
(GyrI-like)
PF12833
(HTH_18) 		4 TYR A 145
THR A  69
LEU A  68
THR A 184
 None
 0.69A 5ov9B-1d5yA:
undetectable		 5ov9B-1d5yA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3d [NIFE] HYDROGENASE
LARGE SUBUNIT

(Desulfovibrio
desulfuricans) 		PF00374
(NiFeSe_Hases) 		4 THR B  77
LEU B  80
THR B 226
VAL B 234
 FNE  B 543 ( 4.4A)
None
None
None
 1.24A 5ov9B-1e3dB:
undetectable		 5ov9B-1e3dB:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6v METHYL-COENZYME M
REDUCTASE I ALPHA
SUBUNIT
METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT
METHYL-COENZYME M
REDUCTASE I GAMMA
SUBUNIT

(Methanopyrus
kandleri;
Methanopyrus
kandleri;
Methanopyrus
kandleri) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N)
PF02241
(MCR_beta)
PF02783
(MCR_beta_N)
PF02240
(MCR_gamma) 		4 LEU B 333
TYR B 334
THR C 118
TYR A 447
 None
 1.22A 5ov9B-1e6vB:
undetectable		 5ov9B-1e6vB:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ey1 ANTITERMINATION
FACTOR NUSB

(Escherichia
coli) 		PF01029
(NusB) 		4 THR A  59
LEU A  62
TYR A  61
VAL A 133
 None
 1.14A 5ov9B-1ey1A:
undetectable		 5ov9B-1ey1A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kps RAN-GTPASE
ACTIVATING PROTEIN 1

(Mus musculus) 		PF07834
(RanGAP1_C) 		4 TYR B 552
ASP B 497
LEU B 493
VAL B 478
 None
 1.04A 5ov9B-1kpsB:
undetectable		 5ov9B-1kpsB:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5n EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
GTP-BINDING SUBUNIT

(Schizosaccharomyces
pombe) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3) 		4 TYR A 639
ASP A 220
THR A 585
VAL A 225
 None
 1.30A 5ov9B-1r5nA:
undetectable		 5ov9B-1r5nA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rrh SEED LIPOXYGENASE-3

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		4 ASP A 794
THR A 795
THR A 792
TYR A 651
 None
 1.12A 5ov9B-1rrhA:
undetectable		 5ov9B-1rrhA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uqw PUTATIVE BINDING
PROTEIN YLIB

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		4 ASP A  25
THR A  26
LEU A  27
THR A  16
 None
 1.25A 5ov9B-1uqwA:
undetectable		 5ov9B-1uqwA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfu CALMODULIN-SENSITIVE
ADENYLATE CYCLASE

(Bacillus
anthracis) 		PF03497
(Anthrax_toxA)
PF07737
(ATLF) 		4 TYR A 492
THR A 345
VAL A 564
TYR A 569
 None
 1.29A 5ov9B-1xfuA:
undetectable		 5ov9B-1xfuA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xyu MAJOR PRION PROTEIN

(Ovis aries) 		PF00377
(Prion) 		4 TYR A 157
ASP A 202
THR A 199
TYR A 149
 None
 1.28A 5ov9B-1xyuA:
undetectable		 5ov9B-1xyuA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yi7 BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE

(Clostridium
acetobutylicum) 		PF04616
(Glyco_hydro_43) 		4 TYR A  26
ASP A  24
THR A  23
VAL A 322
 None
 1.14A 5ov9B-1yi7A:
undetectable		 5ov9B-1yi7A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yns E-1 ENZYME

(Homo sapiens) 		no annotation 4 THR A 211
LEU A 210
THR A  21
VAL A 139
 None
 1.27A 5ov9B-1ynsA:
undetectable		 5ov9B-1ynsA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g7z CONSERVED
HYPOTHETICAL PROTEIN
SPY1493

(Streptococcus
pyogenes) 		PF02645
(DegV) 		4 ASP A 214
THR A 210
LEU A 213
TYR A 249
 None
 0.96A 5ov9B-2g7zA:
1.6		 5ov9B-2g7zA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ibd POSSIBLE
TRANSCRIPTIONAL
REGULATOR

(Rhodococcus
jostii) 		PF00440
(TetR_N) 		4 TYR A  77
THR A  97
TYR A  99
VAL A 171
 None
 1.28A 5ov9B-2ibdA:
undetectable		 5ov9B-2ibdA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mhd UNCHARACTERIZED
PROTEIN

(Bacteroides
uniformis) 		PF13648
(Lipocalin_4) 		4 ASP A  70
THR A  76
VAL A  41
TYR A  39
 None
 1.19A 5ov9B-2mhdA:
undetectable		 5ov9B-2mhdA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pex TRANSCRIPTIONAL
REGULATOR OHRR

(Xanthomonas
campestris) 		PF01047
(MarR) 		4 THR A  46
LEU A  40
TYR A  50
VAL A 125
 FMT  A 201 (-2.9A)
None
None
None
 1.29A 5ov9B-2pexA:
undetectable		 5ov9B-2pexA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ph5 HOMOSPERMIDINE
SYNTHASE

(Legionella
pneumophila) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 ASP A 357
LEU A 359
THR A 392
TYR A 321
 None
 1.17A 5ov9B-2ph5A:
undetectable		 5ov9B-2ph5A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzs PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		4 THR A  72
TYR A  69
THR A  60
VAL A 129
 None
 1.21A 5ov9B-2wzsA:
undetectable		 5ov9B-2wzsA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yeq ALKALINE PHOSPHATASE
D

(Bacillus
subtilis) 		PF09423
(PhoD)
PF16655
(PhoD_N) 		4 TYR A 281
ASP A 277
LEU A 261
TYR A 239
 None
 1.21A 5ov9B-2yeqA:
undetectable		 5ov9B-2yeqA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a52 COLD-ACTIVE ALKALINE
PHOSPHATASE

(Shewanella sp.
AP1) 		PF00245
(Alk_phosphatase) 		4 THR A 117
LEU A 116
THR A  87
VAL A 218
 None
 1.23A 5ov9B-3a52A:
undetectable		 5ov9B-3a52A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a8k AMINOMETHYLTRANSFERA
SE

(Escherichia
coli) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 ASP A 120
LEU A  98
THR A 116
VAL A  94
 None
 1.21A 5ov9B-3a8kA:
undetectable		 5ov9B-3a8kA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aiv BETA-GLUCOSIDASE

(Secale cereale) 		PF00232
(Glyco_hydro_1) 		4 TYR A 348
ASP A 355
THR A 351
THR A 354
 None
 0.98A 5ov9B-3aivA:
1.8		 5ov9B-3aivA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpj GTP-BINDING PROTEIN
YPT31/YPT8

(Saccharomyces
cerevisiae) 		PF00071
(Ras) 		4 ASP B  68
LEU B  18
THR B  69
VAL B  24
 MG  B1208 ( 4.2A)
None
None
GDP  B1207 ( 4.3A)
 1.27A 5ov9B-3cpjB:
undetectable		 5ov9B-3cpjB:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d2l SAM-DEPENDENT
METHYLTRANSFERASE

(Exiguobacterium
sibiricum) 		PF13649
(Methyltransf_25) 		4 THR A 194
LEU A 177
VAL A   9
TYR A  10
 None
 1.16A 5ov9B-3d2lA:
undetectable		 5ov9B-3d2lA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0j DNA POLYMERASE
SUBUNIT DELTA-3

(Homo sapiens) 		PF09507
(CDC27) 		4 ASP B 118
THR B 117
VAL B  34
TYR B  23
 None
 1.17A 5ov9B-3e0jB:
undetectable		 5ov9B-3e0jB:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ele AMINO TRANSFERASE

([Eubacterium]
rectale) 		PF00155
(Aminotran_1_2) 		4 THR A 320
LEU A 319
TYR A 324
VAL A 370
 None
 1.25A 5ov9B-3eleA:
undetectable		 5ov9B-3eleA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		4 ASP A 205
LEU A 207
TYR A 208
VAL A 135
 None
 1.06A 5ov9B-3fdhA:
undetectable		 5ov9B-3fdhA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gfv UNCHARACTERIZED ABC
TRANSPORTER
SOLUTE-BINDING
PROTEIN YCLQ

(Bacillus
subtilis) 		PF01497
(Peripla_BP_2) 		4 TYR A  68
ASP A  46
THR A  47
VAL A  39
 None
 1.17A 5ov9B-3gfvA:
undetectable		 5ov9B-3gfvA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 THR A 859
LEU A 862
VAL A 890
TYR A 894
 None
 1.05A 5ov9B-3jb9A:
undetectable		 5ov9B-3jb9A:
12.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n70 TRANSPORT ACTIVATOR

(Escherichia
coli) 		PF14532
(Sigma54_activ_2) 		4 THR A 203
LEU A 202
VAL A 223
TYR A 199
 None
 0.97A 5ov9B-3n70A:
undetectable		 5ov9B-3n70A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ndc PRECORRIN-4
C(11)-METHYLTRANSFER
ASE

(Rhodobacter
capsulatus) 		PF00590
(TP_methylase) 		4 THR A 150
LEU A 151
VAL A 224
TYR A 181
 None
 1.29A 5ov9B-3ndcA:
undetectable		 5ov9B-3ndcA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmk NUCLEOCAPSID PROTEIN

(Recombinant
vesicular
stomatitis
Indiana virus
rVSV-G/GFP) 		PF00945
(Rhabdo_ncap) 		4 ASP A 131
THR A 127
VAL A  55
TYR A  72
 None
 1.24A 5ov9B-3pmkA:
undetectable		 5ov9B-3pmkA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qkw NUCLEOTIDE SUGAR
SYNTHETASE-LIKE
PROTEIN

(Streptococcus
parasanguinis) 		no annotation 4 TYR A 120
ASP A  81
THR A  78
THR A  74
 None
 1.26A 5ov9B-3qkwA:
undetectable		 5ov9B-3qkwA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 TYR A 396
ASP A 398
LEU A 400
TYR A 320
 None
 1.00A 5ov9B-3sghA:
undetectable		 5ov9B-3sghA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vqr PUTATIVE
OXIDOREDUCTASE

(Aeropyrum
pernix) 		PF01266
(DAO) 		4 TYR A  21
THR A  67
VAL A 163
TYR A 167
 None
 1.12A 5ov9B-3vqrA:
undetectable		 5ov9B-3vqrA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wiw GLYCOSYL HYDROLASE
FAMILY 88

(Pedobacter
heparinus) 		PF07470
(Glyco_hydro_88) 		4 THR A 200
THR A 205
VAL A 229
TYR A 222
 None
 1.28A 5ov9B-3wiwA:
undetectable		 5ov9B-3wiwA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzf ASPARTATE
AMINOTRANSFERASE,
CYTOPLASMIC

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 LEU A 119
TYR A 123
THR A 131
VAL A 186
 None
 1.00A 5ov9B-3wzfA:
2.2		 5ov9B-3wzfA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		4 ASP A 172
LEU A 175
THR A 190
VAL A  45
 CPS  A1316 (-3.9A)
None
None
None
 1.12A 5ov9B-4cztA:
undetectable		 5ov9B-4cztA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djt GTP-BINDING NUCLEAR
PROTEIN GSP1

(Encephalitozoon
cuniculi) 		PF00071
(Ras) 		4 ASP A  63
LEU A  12
THR A  64
VAL A  18
 MG  A 302 ( 4.0A)
None
None
GDP  A 301 (-3.9A)
 1.30A 5ov9B-4djtA:
undetectable		 5ov9B-4djtA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e9k HYPOTHETICAL PROTEIN

(Bacteroides
ovatus) 		PF14717
(DUF4465) 		4 THR A  68
LEU A  67
VAL A  79
TYR A  64
 None
None
None
SO4  A 300 (-4.5A)
 0.90A 5ov9B-4e9kA:
undetectable		 5ov9B-4e9kA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ezi UNCHARACTERIZED
PROTEIN

(Legionella
pneumophila) 		no annotation 4 THR A 245
LEU A 248
VAL A 158
TYR A 157
 None
PEG  A 501 ( 4.8A)
None
None
 1.02A 5ov9B-4eziA:
14.4		 5ov9B-4eziA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgu LEGUMAIN

(Homo sapiens) 		PF01650
(Peptidase_C13) 		4 ASP A 309
THR A 313
LEU A 312
TYR A 400
 None
 1.21A 5ov9B-4fguA:
2.5		 5ov9B-4fguA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fvv NEUROTOXIN

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 ASP A 881
THR A 882
VAL A 926
TYR A 927
 None
 1.14A 5ov9B-4fvvA:
undetectable		 5ov9B-4fvvA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hr6 LECTIN
LECTIN
LECTIN

(Trichosanthes
anguina;
Trichosanthes
anguina;
Trichosanthes
anguina) 		no annotation
PF00161
(RIP)
PF00652
(Ricin_B_lectin) 		4 TYR A  35
THR B 208
VAL C 131
TYR B 234
 None
 0.85A 5ov9B-4hr6A:
undetectable		 5ov9B-4hr6A:
6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igl YENB
YENC2

(Yersinia
entomophaga;
Yersinia
entomophaga) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN)
no annotation 		4 ASP A1480
THR A1481
THR B   9
TYR B 372
 K  A1505 (-2.7A)
None
K  A1505 (-3.7A)
None
 1.24A 5ov9B-4iglA:
undetectable		 5ov9B-4iglA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3o OUTER MEMBRANE USHER
PROTEIN FIMD

(Escherichia
coli) 		PF00577
(Usher)
PF13953
(PapC_C)
PF13954
(PapC_N) 		4 ASP D 695
THR D 694
TYR D 699
THR D 664
 None
 0.94A 5ov9B-4j3oD:
undetectable		 5ov9B-4j3oD:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n5i ESTERASE/LIPASE

(Lactobacillus
rhamnosus) 		PF07859
(Abhydrolase_3) 		4 THR X  52
LEU X  53
VAL X  99
TYR X  56
 None
 0.89A 5ov9B-4n5iX:
20.9		 5ov9B-4n5iX:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 ASP A1498
THR A1499
THR A1525
TYR A1874
 None
 1.21A 5ov9B-4o9xA:
undetectable		 5ov9B-4o9xA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o9x TCDB2, TCCC3

(Photorhabdus
luminescens) 		PF03534
(SpvB)
PF12255
(TcdB_toxin_midC)
PF12256
(TcdB_toxin_midN) 		4 ASP A1498
THR A1499
TYR A1522
THR A1525
 None
 1.01A 5ov9B-4o9xA:
undetectable		 5ov9B-4o9xA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qoa PUTATIVE PERIPLASMIC
PROTEIN

(Bacteroides
uniformis) 		PF11396
(PepSY_like) 		4 ASP A  69
THR A  68
LEU A  67
VAL A  84
 None
 1.25A 5ov9B-4qoaA:
undetectable		 5ov9B-4qoaA:
12.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qww ACETYLCHOLINESTERASE

(Bungarus
fasciatus) 		PF00135
(COesterase) 		4 ASP A  72
THR A  73
TYR A  75
THR A  81
 None
 0.39A 5ov9B-4qwwA:
62.4		 5ov9B-4qwwA:
63.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rs2 PREDICTED
ACYLTRANSFERASE WITH
ACYL-COA
N-ACYLTRANSFERASE
DOMAIN

(Escherichia
coli) 		PF13508
(Acetyltransf_7) 		4 THR A  41
LEU A  42
VAL A  45
TYR A  56
 None
 0.74A 5ov9B-4rs2A:
undetectable		 5ov9B-4rs2A:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rsi STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
2
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF06470
(SMC_hinge)
PF06470
(SMC_hinge) 		4 THR A 637
TYR A 659
THR A 642
VAL B 721
 None
 1.29A 5ov9B-4rsiA:
undetectable		 5ov9B-4rsiA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE LARGE
SUBUNIT

(Desulfovibrio
vulgaris) 		PF00374
(NiFeSe_Hases) 		4 THR L  87
LEU L  90
THR L 236
VAL L 244
 NWN  L 601 ( 4.4A)
None
None
None
 1.25A 5ov9B-4u9iL:
undetectable		 5ov9B-4u9iL:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uph SULFATASE (SULFURIC
ESTER HYDROLASE)
PROTEIN

(Agrobacterium
tumefaciens) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		4 ASP A 302
THR A 303
LEU A 305
VAL A 354
 None
 1.25A 5ov9B-4uphA:
undetectable		 5ov9B-4uphA:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w6q GLUCOSYLTRANSFERASE

(Streptococcus
agalactiae) 		no annotation 4 TYR A 120
ASP A  81
THR A  78
THR A  74
 None
 1.29A 5ov9B-4w6qA:
undetectable		 5ov9B-4w6qA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wgx MOLINATE HYDROLASE

(Gulosibacter
molinativorax) 		PF01979
(Amidohydro_1) 		4 ASP A 369
THR A 365
LEU A 366
THR A 341
 None
 0.88A 5ov9B-4wgxA:
2.2		 5ov9B-4wgxA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xqe HOMOSPERMIDINE
SYNTHASE

(Blastochloris
viridis) 		PF03435
(Sacchrp_dh_NADP)
PF16653
(Sacchrp_dh_C) 		4 ASP A 361
LEU A 363
THR A 396
TYR A 325
 AG2  A 505 ( 3.8A)
AG2  A 505 ( 4.5A)
AG2  A 505 ( 3.9A)
AG2  A 505 ( 4.2A)
 1.23A 5ov9B-4xqeA:
undetectable		 5ov9B-4xqeA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydf HTLV-1 PROTEASE

(Primate
T-lymphotropic
virus 1) 		PF00077
(RVP) 		4 THR A  88
LEU A  87
THR A  70
VAL A  17
 None
 1.01A 5ov9B-4ydfA:
undetectable		 5ov9B-4ydfA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ys6 PUTATIVE
SOLUTE-BINDING
COMPONENT OF ABC
TRANSPORTER

(Lachnoclostridium
phytofermentans) 		PF13407
(Peripla_BP_4) 		4 LEU A 218
TYR A 212
THR A 216
VAL A 179
 None
 0.99A 5ov9B-4ys6A:
undetectable		 5ov9B-4ys6A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yu5 IMMUNE INHIBITOR A,
METALLOPROTEASE

(Bacillus cereus) 		PF05547
(Peptidase_M6) 		4 ASP A 758
LEU A 777
VAL A 477
TYR A 646
 None
 1.13A 5ov9B-4yu5A:
undetectable		 5ov9B-4yu5A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c2v HYDRAZINE SYNTHASE
ALPHA SUBUNIT

(Candidatus
Kuenenia
stuttgartiensis) 		no annotation 4 THR A 777
LEU A 776
VAL A 746
TYR A 750
 None
HEC  A 906 (-4.2A)
None
None
 1.09A 5ov9B-5c2vA:
undetectable		 5ov9B-5c2vA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djs TETRATRICOPEPTIDE
TPR_2 REPEAT PROTEIN

(Thermobaculum
terrenum) 		PF13181
(TPR_8)
PF13844
(Glyco_transf_41) 		4 THR A 401
LEU A 404
THR A 406
VAL A 433
 None
 1.10A 5ov9B-5djsA:
undetectable		 5ov9B-5djsA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es6 LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A

(Brevibacillus
parabrevis) 		PF00501
(AMP-binding)
PF00551
(Formyl_trans_N) 		4 THR A 404
LEU A 407
VAL A 213
TYR A 231
 None
 1.21A 5ov9B-5es6A:
1.4		 5ov9B-5es6A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es9 LINEAR GRAMICIDIN
SYNTHETASE SUBUNIT A

(Brevibacillus
parabrevis) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00551
(Formyl_trans_N)
PF13193
(AMP-binding_C) 		4 THR A 404
LEU A 407
VAL A 213
TYR A 231
 None
 1.19A 5ov9B-5es9A:
undetectable		 5ov9B-5es9A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f75 THIOCYANATE
DEHYDROGENASE

(Thioalkalivibrio
paradoxus) 		no annotation 4 ASP A 129
THR A 130
VAL A 153
TYR A 180
 None
 1.19A 5ov9B-5f75A:
undetectable		 5ov9B-5f75A:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmf RNA POLYMERASE II
PRE-INITIATION
COMPLEX, TOA1

(Saccharomyces
cerevisiae) 		PF03153
(TFIIA) 		4 THR M  47
LEU M  46
THR M  52
VAL M   9
 None
 1.15A 5ov9B-5fmfM:
undetectable		 5ov9B-5fmfM:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1q INNEXIN-6

(Caenorhabditis
elegans) 		PF00876
(Innexin) 		4 THR A 268
LEU A 269
VAL A 108
TYR A 104
 None
 1.09A 5ov9B-5h1qA:
undetectable		 5ov9B-5h1qA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hee PUTATIVE
UNCHARACTERIZED
PROTEIN, TK2203
PROTEIN

(Thermococcus
kodakarensis) 		PF02900
(LigB) 		4 THR A 137
LEU A 136
THR A 100
VAL A 153
 None
 1.28A 5ov9B-5heeA:
undetectable		 5ov9B-5heeA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4a ARGONAUTE PROTEIN

(Marinitoga
piezophila) 		no annotation 4 TYR A 216
ASP A 212
TYR A 166
THR A 209
 None
None
A  B   7 ( 4.1A)
A  B   7 ( 3.0A)
 1.03A 5ov9B-5i4aA:
undetectable		 5ov9B-5i4aA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnf LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A

(Brevibacillus
parabrevis) 		no annotation 4 THR C 404
LEU C 407
VAL C 213
TYR C 231
 None
 1.20A 5ov9B-5jnfC:
1.5		 5ov9B-5jnfC:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0y EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT G

(Homo sapiens) 		PF00076
(RRM_1) 		4 TYR O 305
ASP O 254
THR O 250
THR O 253
 None
 1.16A 5ov9B-5k0yO:
undetectable		 5ov9B-5k0yO:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ls2 LYSM TYPE RECEPTOR
KINASE

(Lotus japonicus) 		no annotation 4 THR A 126
LEU A 130
TYR A 113
VAL A 107
 None
 1.25A 5ov9B-5ls2A:
undetectable		 5ov9B-5ls2A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfh METHIONYL-TRNA
SYNTHETASE, PUTATIVE

(Trypanosoma
brucei) 		no annotation 4 TYR A 250
ASP A 287
THR A 332
VAL A 471
 MET  A 807 (-3.2A)
MET  A 807 (-3.6A)
None
None
 1.02A 5ov9B-5nfhA:
undetectable		 5ov9B-5nfhA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nxk SERINE-RICH SECRETED
CELL WALL ANCHORED
(LPXTG-MOTIF )
PROTEIN

(Lactobacillus
reuteri) 		no annotation 4 THR A 372
LEU A 373
VAL A 366
TYR A 363
 None
 1.02A 5ov9B-5nxkA:
undetectable		 5ov9B-5nxkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oed GTGE
RAS-RELATED PROTEIN
RAB-32

(Salmonella
enterica;
Homo sapiens) 		no annotation
no annotation 		4 TYR A  42
ASP A  35
THR A  37
VAL B  66
 None
None
None
MLY  B  65 ( 3.1A)
 1.12A 5ov9B-5oedA:
undetectable		 5ov9B-5oedA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oj2 MAM
DOMAIN-CONTAINING
GLYCOSYLPHOSPHATIDYL
INOSITOL ANCHOR
PROTEIN 1

(Gallus gallus) 		PF13927
(Ig_3) 		4 THR A  92
LEU A  93
VAL A 124
TYR A  48
 None
 1.29A 5ov9B-5oj2A:
undetectable		 5ov9B-5oj2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovt BPH

(Thiobacillus
denitrificans) 		no annotation 4 ASP A  17
THR A  18
LEU A  19
THR A   1
 None
None
None
PO4  A 301 ( 4.5A)
 1.00A 5ov9B-5ovtA:
undetectable		 5ov9B-5ovtA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tge PHAGE TERMINASE
LARGE SUBUNIT

(Thermus virus
P74-26) 		PF17289
(Terminase_6C) 		4 TYR A 271
ASP A 398
THR A 400
VAL A 303
 None
 1.25A 5ov9B-5tgeA:
undetectable		 5ov9B-5tgeA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ub8 LIKELY RAB FAMILY
GTP-BINDING PROTEIN

(Candida
albicans) 		PF00071
(Ras) 		4 ASP A  70
LEU A  20
THR A  71
VAL A  26
 ZN  A 302 ( 3.9A)
None
None
GDP  A 301 (-4.1A)
 1.22A 5ov9B-5ub8A:
undetectable		 5ov9B-5ub8A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v1w GLYCOSIDE HYDROLASE

(Bacillus
halodurans) 		PF03639
(Glyco_hydro_81) 		4 TYR A 624
THR A 603
VAL A 588
TYR A 644
 None
 1.21A 5ov9B-5v1wA:
undetectable		 5ov9B-5v1wA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wg6 HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2,POLYCOMB
PROTEIN SUZ12
(E.C.2.1.1.43)
CHIMERA

(Homo sapiens) 		no annotation 4 ASP A 676
LEU A 666
THR A 678
VAL A 657
 None
None
A9G  A9009 (-3.7A)
A9G  A9009 ( 4.7A)
 1.16A 5ov9B-5wg6A:
undetectable		 5ov9B-5wg6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wql TAIL-SPECIFIC
PROTEASE

(Escherichia
coli) 		no annotation 4 THR C 190
LEU C 191
TYR C 195
VAL C 133
 None
 1.19A 5ov9B-5wqlC:
undetectable		 5ov9B-5wqlC:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6s ACETYLXYLAN ESTERASE
A

(Aspergillus
awamori) 		PF10503
(Esterase_phd) 		4 TYR A  53
ASP A 268
THR A 140
VAL A 261
 None
 1.12A 5ov9B-5x6sA:
14.1		 5ov9B-5x6sA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dd3 CYTOSOLIC PURINE
5'-NUCLEOTIDASE

(Homo sapiens) 		no annotation 4 ASP A 103
THR A 104
LEU A 105
TYR A 137
 None
 0.92A 5ov9B-6dd3A:
undetectable		 5ov9B-6dd3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei3 PROTON-DEPENDENT
OLIGOPEPTIDE
TRANSPORTER FAMILY
PROTEIN

(Xanthomonas
campestris) 		no annotation 4 THR A 377
LEU A 379
THR A 431
VAL A 314
 None
78M  A 609 (-4.3A)
None
None
 1.11A 5ov9B-6ei3A:
undetectable		 5ov9B-6ei3A:
23.26