SIMILAR PATTERNS OF AMINO ACIDS FOR 5OTR_A_ACTA402

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bpl ALPHA-1,4-GLUCAN-4-G
LUCANOHYDROLASE

(Bacillus
licheniformis) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL B 283
ASP B 285
PRO B 287
ALA B 320
 None
 0.95A 5otrA-1bplB:
undetectable		 5otrA-1bplB:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gn4 SUPEROXIDE DISMUTASE

(Mycobacterium
tuberculosis) 		PF00081
(Sod_Fe_N)
PF02777
(Sod_Fe_C) 		4 TYR A   4
VAL A  44
ASP A  42
ALA A  43
 None
 0.86A 5otrA-1gn4A:
undetectable		 5otrA-1gn4A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gyc LACCASE 2

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.81A 5otrA-1gycA:
undetectable		 5otrA-1gycA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jio CYTOCHROME P450
107A1

(Saccharopolyspora
erythraea) 		PF00067
(p450) 		4 TYR A  20
ASP A 322
PRO A 323
ALA A 319
 None
 0.99A 5otrA-1jioA:
undetectable		 5otrA-1jioA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kya LACCASE

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.81A 5otrA-1kyaA:
undetectable		 5otrA-1kyaA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lfw PEPV

(Lactobacillus
delbrueckii) 		PF01546
(Peptidase_M20) 		4 VAL A 235
ASP A 231
PRO A 230
ALA A 234
 None
 0.87A 5otrA-1lfwA:
undetectable		 5otrA-1lfwA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1of5 MRNA EXPORT FACTOR
MEX67

(Saccharomyces
cerevisiae) 		no annotation 4 TYR A 389
VAL A 450
PRO A 453
ALA A 461
 None
 1.12A 5otrA-1of5A:
undetectable		 5otrA-1of5A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pto PERTUSSIS TOXIN

(Bordetella
pertussis) 		PF02918
(Pertussis_S2S3)
PF03440
(APT) 		4 TYR B 174
VAL B   6
ASP B 178
ALA B 179
 None
 1.11A 5otrA-1ptoB:
undetectable		 5otrA-1ptoB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pto PERTUSSIS TOXIN

(Bordetella
pertussis) 		PF02918
(Pertussis_S2S3)
PF03440
(APT) 		4 TYR C 174
VAL C   6
ASP C 178
ALA C 179
 None
 1.13A 5otrA-1ptoC:
undetectable		 5otrA-1ptoC:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlt PUTATIVE
OXIDOREDUCTASE
(VIRULENCE FACTOR
MVIM HOMOLOG)

(Escherichia
coli) 		PF01408
(GFO_IDH_MocA) 		4 TYR A 167
VAL A 299
PRO A  97
ALA A 295
 None
 1.07A 5otrA-1tltA:
undetectable		 5otrA-1tltA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulv GLUCODEXTRANASE

(Arthrobacter
globiformis) 		PF00723
(Glyco_hydro_15)
PF09136
(Glucodextran_B)
PF09137
(Glucodextran_N)
PF09985
(Glucodextran_C) 		4 TYR A 253
VAL A 107
ASP A 109
PRO A 110
 None
 1.08A 5otrA-1ulvA:
undetectable		 5otrA-1ulvA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v10 LACCASE

(Rigidoporus
microporus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.86A 5otrA-1v10A:
undetectable		 5otrA-1v10A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjs ALPHA-AMYLASE

(Bacillus
licheniformis) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL A 283
ASP A 285
PRO A 287
ALA A 320
 None
 0.98A 5otrA-1vjsA:
undetectable		 5otrA-1vjsA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk9 VALYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1) 		4 VAL A 228
ASP A 257
PRO A 258
ALA A 227
 None
 1.10A 5otrA-1wk9A:
undetectable		 5otrA-1wk9A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y0y FRV OPERON PROTEIN
FRVX

(Pyrococcus
horikoshii) 		PF05343
(Peptidase_M42) 		4 TYR A 288
ASP A 333
PRO A 318
ALA A 336
 None
 1.12A 5otrA-1y0yA:
undetectable		 5otrA-1y0yA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cwf DELTA1-PIPERIDEINE-2
-CARBOXYLATE
REDUCTASE

(Pseudomonas
syringae group
genomosp. 3) 		PF02615
(Ldh_2) 		4 VAL A 280
ASP A 282
PRO A 283
ALA A 111
 None
 0.72A 5otrA-2cwfA:
undetectable		 5otrA-2cwfA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2die AMYLASE

(Bacillus sp.
(in: Bacteria)) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		4 VAL A 288
ASP A 290
PRO A 292
ALA A 325
 None
 0.87A 5otrA-2dieA:
undetectable		 5otrA-2dieA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dpn GLYCEROL KINASE

(Thermus
thermophilus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 TYR A 351
VAL A 485
PRO A 342
ALA A 488
 None
 1.09A 5otrA-2dpnA:
undetectable		 5otrA-2dpnA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gzb KUNITZ-TYPE
PROTEINASE INHIBITOR
BBCI

(Bauhinia
bauhinioides) 		PF00197
(Kunitz_legume) 		4 VAL A  45
ASP A  47
PRO A  48
ALA A  31
 None
 1.14A 5otrA-2gzbA:
undetectable		 5otrA-2gzbA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hqo PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Helicobacter
pylori) 		PF00072
(Response_reg) 		4 TYR A  94
VAL A  73
ASP A  92
ALA A  91
 None
 1.07A 5otrA-2hqoA:
undetectable		 5otrA-2hqoA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hzh LACCASE

(Trametes
ochracea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.82A 5otrA-2hzhA:
undetectable		 5otrA-2hzhA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oxt NUCLEOSIDE-2'-O-METH
YLTRANSFERASE

(Meaban virus) 		PF01728
(FtsJ) 		4 TYR A  90
VAL A 125
ASP A  80
ALA A 103
 None
None
SAM  A 300 ( 4.6A)
None
 1.13A 5otrA-2oxtA:
undetectable		 5otrA-2oxtA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2phk PHOSPHORYLASE KINASE

(Oryctolagus
cuniculus) 		PF00069
(Pkinase) 		4 TYR A 206
VAL A 210
PRO A 272
ALA A 191
 None
 0.86A 5otrA-2phkA:
26.1		 5otrA-2phkA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qmx PREPHENATE
DEHYDRATASE

(Chlorobaculum
tepidum) 		PF00800
(PDT) 		4 TYR A  15
VAL A  79
PRO A  50
ALA A  19
 ACT  A 301 (-4.5A)
None
None
None
 1.03A 5otrA-2qmxA:
undetectable		 5otrA-2qmxA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qt6 LACCASE

(Lentinus
tigrinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.80A 5otrA-2qt6A:
undetectable		 5otrA-2qt6A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qxl HEAT SHOCK PROTEIN
HOMOLOG SSE1

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 VAL A 172
ASP A 174
PRO A 147
ALA A 144
 None
 1.03A 5otrA-2qxlA:
undetectable		 5otrA-2qxlA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ri8 MANNOSYL-OLIGOSACCHA
RIDE
ALPHA-1,2-MANNOSIDAS
E

(Penicillium
citrinum) 		PF01532
(Glyco_hydro_47) 		4 VAL A1508
ASP A1280
PRO A1281
ALA A1509
 None
 1.05A 5otrA-2ri8A:
undetectable		 5otrA-2ri8A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4o CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE IV

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 218
VAL A 222
PRO A 285
ALA A 209
 None
 0.80A 5otrA-2w4oA:
21.0		 5otrA-2w4oA:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.77A 5otrA-2xybA:
undetectable		 5otrA-2xybA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3t CYTOCHROME P450

(Streptomyces
sp. TP-A0274) 		PF00067
(p450) 		4 TYR A  26
ASP A 335
PRO A 336
ALA A 332
 None
 0.93A 5otrA-2z3tA:
undetectable		 5otrA-2z3tA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2k TRNA(ILE)-LYSIDINE
SYNTHASE

(Geobacillus
kaustophilus) 		PF01171
(ATP_bind_3)
PF09179
(TilS)
PF11734
(TilS_C) 		4 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
 0.66A 5otrA-3a2kA:
undetectable		 5otrA-3a2kA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bc8 O-PHOSPHOSERYL-TRNA(
SEC) SELENIUM
TRANSFERASE

(Mus musculus) 		PF05889
(SepSecS) 		4 VAL A 250
ASP A 276
PRO A 248
ALA A 277
 None
 1.10A 5otrA-3bc8A:
undetectable		 5otrA-3bc8A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3buj CALO2

(Micromonospora
echinospora) 		PF00067
(p450) 		4 TYR A  19
ASP A 314
PRO A 315
ALA A 311
 None
 0.99A 5otrA-3bujA:
undetectable		 5otrA-3bujA:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bw2 2-NITROPROPANE
DIOXYGENASE

(Streptomyces
ansochromogenes) 		PF03060
(NMO) 		4 VAL A 212
ASP A 232
PRO A 210
ALA A 233
 None
 0.96A 5otrA-3bw2A:
undetectable		 5otrA-3bw2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4a PROBABLE TRYPTOPHAN
HYDROXYLASE VIOD

(Chromobacterium
violaceum) 		no annotation 4 TYR A  60
VAL A 286
PRO A  10
ALA A 289
 None
None
FAD  A 401 (-3.4A)
None
 1.14A 5otrA-3c4aA:
undetectable		 5otrA-3c4aA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cux MALATE SYNTHASE

(Bacillus
anthracis) 		PF01274
(Malate_synthase) 		4 TYR A 191
VAL A 137
ASP A 135
ALA A 136
 None
 1.05A 5otrA-3cuxA:
undetectable		 5otrA-3cuxA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cv2 MALATE SYNTHASE A

(Escherichia
coli) 		PF01274
(Malate_synthase) 		4 TYR A 194
VAL A 140
ASP A 138
ALA A 139
 None
 1.05A 5otrA-3cv2A:
undetectable		 5otrA-3cv2A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbk ELASTASE

(Pseudomonas
aeruginosa) 		PF01447
(Peptidase_M4)
PF02868
(Peptidase_M4_C) 		4 TYR A 265
VAL A 295
PRO A 298
ALA A 269
 None
 1.14A 5otrA-3dbkA:
undetectable		 5otrA-3dbkA:
20.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e3b CASEIN KINASE II
SUBUNIT ALPHA'

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR X  40
VAL X 102
PRO X 105
ALA X 111
 None
 0.86A 5otrA-3e3bX:
45.7		 5otrA-3e3bX:
83.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ejb BIOTIN BIOSYNTHESIS
CYTOCHROME P450-LIKE
ENZYME

(Bacillus
subtilis) 		PF00067
(p450) 		4 TYR B  19
ASP B 315
PRO B 316
ALA B 312
 None
 1.03A 5otrA-3ejbB:
undetectable		 5otrA-3ejbB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fou QUINOL-CYTOCHROME C
REDUCTASE, RIESKE
IRON-SULFUR SUBUNIT

(Thermus
thermophilus) 		PF00355
(Rieske) 		4 VAL A 188
ASP A  56
PRO A  89
ALA A 189
 None
 1.10A 5otrA-3fouA:
undetectable		 5otrA-3fouA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE

(Geobacillus
kaustophilus) 		PF11734
(TilS_C) 		4 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.71A 5otrA-3hj7A:
undetectable		 5otrA-3hj7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hpd HYDROXYETHYLTHIAZOLE
KINASE

(Pyrococcus
horikoshii) 		PF02110
(HK) 		4 VAL A  90
ASP A  92
PRO A  93
ALA A 198
 None
 1.07A 5otrA-3hpdA:
undetectable		 5otrA-3hpdA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jux PROTEIN TRANSLOCASE
SUBUNIT SECA

(Thermotoga
maritima) 		PF00271
(Helicase_C)
PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		4 TYR A  14
VAL A 435
PRO A 438
ALA A  93
 None
 1.13A 5otrA-3juxA:
undetectable		 5otrA-3juxA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kw7 LACCASE B

(Trametes sp.
AH28-2) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.87A 5otrA-3kw7A:
undetectable		 5otrA-3kw7A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3md0 ARGININE/ORNITHINE
TRANSPORT SYSTEM
ATPASE

(Mycobacterium
tuberculosis) 		PF03308
(ArgK) 		4 VAL A 144
ASP A  54
PRO A  53
ALA A 148
 None
 1.03A 5otrA-3md0A:
undetectable		 5otrA-3md0A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3noq THIJ/PFPI FAMILY
PROTEIN

(Pseudomonas
fluorescens) 		PF01965
(DJ-1_PfpI) 		4 VAL A   3
ASP A  30
PRO A  29
ALA A   2
 None
 1.11A 5otrA-3noqA:
undetectable		 5otrA-3noqA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o7o ENDOGLUCANASE

(Thermotoga
maritima) 		PF01670
(Glyco_hydro_12) 		4 TYR A  32
VAL A  36
ASP A  50
ALA A  49
 None
 1.06A 5otrA-3o7oA:
undetectable		 5otrA-3o7oA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p3l CYTOCHROME P450

(Streptomyces
thioluteus) 		PF00067
(p450) 		4 VAL A 321
ASP A 325
PRO A 326
ALA A 322
 None
 1.08A 5otrA-3p3lA:
undetectable		 5otrA-3p3lA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.75A 5otrA-3pxlA:
undetectable		 5otrA-3pxlA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qha PUTATIVE
OXIDOREDUCTASE

(Mycobacterium
avium) 		PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11) 		4 TYR A 150
VAL A 143
PRO A 170
ALA A 167
 None
 1.12A 5otrA-3qhaA:
undetectable		 5otrA-3qhaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rm5 HYDROXYMETHYLPYRIMID
INE/PHOSPHOMETHYLPYR
IMIDINE KINASE THI20

(Saccharomyces
cerevisiae) 		PF03070
(TENA_THI-4)
PF08543
(Phos_pyr_kin) 		4 VAL A 124
ASP A 126
PRO A 127
ALA A 246
 None
SO4  A   1 (-2.8A)
SO4  A   1 (-4.4A)
None
 1.08A 5otrA-3rm5A:
undetectable		 5otrA-3rm5A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 TYR A 133
VAL A 338
ASP A 251
ALA A  51
 None
 1.11A 5otrA-3sghA:
undetectable		 5otrA-3sghA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 127
ASP A 129
PRO A 130
ALA A 104
 None
 0.79A 5otrA-3t6wA:
undetectable		 5otrA-3t6wA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usz EXO-1,3/1,4-BETA-GLU
CANASE

(Pseudoalteromonas
sp. BB1) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 VAL A 525
ASP A 544
PRO A 523
ALA A 545
 None
 1.14A 5otrA-3uszA:
undetectable		 5otrA-3uszA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1b LACCASE

(Lentinus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 147
ASP A 149
PRO A 150
ALA A 124
 None
 0.82A 5otrA-3x1bA:
undetectable		 5otrA-3x1bA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbm CYCLIN-DEPENDENT
KINASE-LIKE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 179
VAL A 183
PRO A 272
ALA A 169
 None
 0.78A 5otrA-4bbmA:
24.9		 5otrA-4bbmA:
29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cfh 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-1

(Rattus
norvegicus) 		PF00069
(Pkinase)
PF16579
(AdenylateSensor) 		4 TYR A 190
VAL A 195
PRO A 253
ALA A 181
 None
 0.96A 5otrA-4cfhA:
8.3		 5otrA-4cfhA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ep6 CYTOCHROME P450-LIKE
PROTEIN XPLA

(Rhodococcus
rhodochrous) 		PF00067
(p450) 		4 TYR A 184
ASP A 472
PRO A 473
ALA A 469
 None
 1.02A 5otrA-4ep6A:
undetectable		 5otrA-4ep6A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f55 SPORE CORTEX-LYTIC
ENZYME

(Bacillus cereus) 		PF07486
(Hydrolase_2) 		4 TYR A 232
VAL A 172
PRO A 225
ALA A 229
 PO4  A 302 (-4.5A)
None
None
None
 0.84A 5otrA-4f55A:
undetectable		 5otrA-4f55A:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fet SPORE CORTEX-LYTIC
ENZYME PREPEPTIDE

(Bacillus
anthracis) 		no annotation 4 TYR B 226
VAL B 166
PRO B 219
ALA B 223
 None
 0.80A 5otrA-4fetB:
undetectable		 5otrA-4fetB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fg8 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 195
VAL A 199
PRO A 261
ALA A 186
 None
 1.12A 5otrA-4fg8A:
21.8		 5otrA-4fg8A:
26.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fie SERINE/THREONINE-PRO
TEIN KINASE PAK 4

(Homo sapiens) 		PF00069
(Pkinase)
PF00786
(PBD) 		4 TYR A 492
VAL A 496
PRO A 557
ALA A 483
 SEP  A 474 ( 4.4A)
None
None
None
 0.76A 5otrA-4fieA:
24.9		 5otrA-4fieA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fxb PUTATIVE CYTOCHROME
P450

(Streptomyces
coelicolor) 		PF00067
(p450) 		4 TYR A  35
ASP A 331
PRO A 332
ALA A 328
 None
 1.01A 5otrA-4fxbA:
undetectable		 5otrA-4fxbA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9i HYDROGENASE
MATURATION PROTEIN
HYPF

(Thermococcus
kodakarensis) 		PF00708
(Acylphosphatase)
PF00814
(Peptidase_M22)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 TYR A 626
VAL A 620
ASP A 616
ALA A 619
 None
 1.04A 5otrA-4g9iA:
undetectable		 5otrA-4g9iA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hgz CCBJ

(Streptomyces
caelestis) 		PF13649
(Methyltransf_25) 		4 VAL A  56
ASP A  29
PRO A  27
ALA A  33
 None
 1.07A 5otrA-4hgzA:
undetectable		 5otrA-4hgzA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhv LACCASE

(Coriolopsis
caperata) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.84A 5otrA-4jhvA:
undetectable		 5otrA-4jhvA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oen SECOND SUBSTRATE
BINDING DOMAIN OF
PUTATIVE AMINO ACID
ABC TRANSPORTER

(Streptococcus
pneumoniae) 		PF00497
(SBP_bac_3) 		4 TYR A 397
VAL A 376
ASP A 418
ALA A 419
 None
 1.10A 5otrA-4oenA:
undetectable		 5otrA-4oenA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1l TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Chromohalobacter
salexigens) 		PF03480
(DctP) 		4 TYR A 200
ASP A  79
PRO A  81
ALA A  75
 BDP  A 401 (-3.8A)
None
None
None
 1.01A 5otrA-4p1lA:
undetectable		 5otrA-4p1lA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rew 5'-AMP-ACTIVATED
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA-1

(Homo sapiens) 		PF00069
(Pkinase)
PF16579
(AdenylateSensor) 		4 TYR A 192
VAL A 197
PRO A 255
ALA A 183
 None
 0.89A 5otrA-4rewA:
24.2		 5otrA-4rewA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xbr PROTEIN
FAM212A,SERINE/THREO
NINE-PROTEIN KINASE
PAK 4

(Homo sapiens) 		PF00069
(Pkinase)
PF15342
(FAM212) 		4 TYR A 492
VAL A 496
PRO A 557
ALA A 483
 SEP  A 474 ( 4.2A)
None
None
None
 0.77A 5otrA-4xbrA:
24.7		 5otrA-4xbrA:
25.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywr PUTATIVE
HYDROXYMETHYLPYRIMID
INE
KINASE/PHOSPHOMETHYL
PYRIMIDINE KINASE

(Acinetobacter
baumannii) 		PF08543
(Phos_pyr_kin) 		4 VAL A 110
ASP A 112
PRO A 113
ALA A 218
 None
PLP  A 300 (-3.1A)
None
None
 1.09A 5otrA-4ywrA:
undetectable		 5otrA-4ywrA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yxt POLYKETIDE
BIOSYNTHESIS
3-HYDROXY-3-METHYLGL
UTARYL-ACP SYNTHASE
PKSG

(Bacillus
subtilis) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 TYR A 367
VAL A  44
PRO A  47
ALA A  16
 None
 0.97A 5otrA-4yxtA:
undetectable		 5otrA-4yxtA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zef AMINO ACID ABC
TRANSPORTER AMINO
ACID-BINDING/PERMEAS
E

(Enterococcus
faecalis) 		PF00497
(SBP_bac_3) 		4 TYR A 391
VAL A 370
ASP A 412
ALA A 413
 None
 1.05A 5otrA-4zefA:
undetectable		 5otrA-4zefA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cq2 E3 UBIQUITIN-PROTEIN
LIGASE ITCHY HOMOLOG

(Homo sapiens) 		PF00397
(WW) 		4 TYR A 495
ASP A 508
PRO A 509
ALA A 515
 None
 1.11A 5otrA-5cq2A:
undetectable		 5otrA-5cq2A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwe CYTOCHROME P450
HYDROXYLASE

(Streptomyces
avermitilis) 		PF00067
(p450) 		4 TYR A  22
ASP A 315
PRO A 316
ALA A 312
 None
 0.93A 5otrA-5cweA:
undetectable		 5otrA-5cweA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.77A 5otrA-5ehfA:
undetectable		 5otrA-5ehfA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32

(Mycobacterium
marinum) 		PF00501
(AMP-binding) 		4 TYR A 610
VAL A 551
PRO A 594
ALA A 516
 None
 0.88A 5otrA-5ey9A:
undetectable		 5otrA-5ey9A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzp TRIOSEPHOSPHATE
ISOMERASE

(Plasmodium
falciparum) 		PF00121
(TIM) 		4 TYR A  90
VAL A  40
PRO A  43
ALA A   8
 None
 1.10A 5otrA-5gzpA:
undetectable		 5otrA-5gzpA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdi CYTOCHROME P450 144

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 TYR A  54
ASP A 356
PRO A 357
ALA A 353
 None
 0.97A 5otrA-5hdiA:
undetectable		 5otrA-5hdiA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kp7 CURD

(Moorea
producens) 		PF01154
(HMG_CoA_synt_N)
PF08540
(HMG_CoA_synt_C) 		4 TYR A 367
VAL A  44
PRO A  47
ALA A  16
 None
 1.02A 5otrA-5kp7A:
undetectable		 5otrA-5kp7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		4 VAL A 251
ASP A 395
PRO A 396
ALA A 254
 None
 1.08A 5otrA-5kqiA:
undetectable		 5otrA-5kqiA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2e GLUTAMATE RECEPTOR
IONOTROPIC,
DELTA-2,GLUTAMATE
RECEPTOR IONOTROPIC,
DELTA-2

(Rattus
norvegicus) 		PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 VAL A 749
ASP A 753
PRO A 754
ALA A 750
 None
 1.10A 5otrA-5l2eA:
undetectable		 5otrA-5l2eA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 127
ASP A 129
PRO A 130
ALA A 104
 None
 0.84A 5otrA-5mewA:
undetectable		 5otrA-5mewA:
20.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mov CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		5 TYR A  39
VAL A 101
ASP A 103
PRO A 104
ALA A 110
 None
 0.00A 5otrA-5movA:
50.8		 5otrA-5movA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4c PROLYL
OLIGOPEPTIDASE

(Galerina
marginata) 		no annotation 4 TYR A 623
VAL A 604
ASP A 606
ALA A 605
 None
 1.10A 5otrA-5n4cA:
undetectable		 5otrA-5n4cA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nth PUTATIVE
AMINOPEPTIDASE

(Leishmania
major) 		PF00883
(Peptidase_M17) 		4 VAL A 510
ASP A 439
PRO A 508
ALA A 437
 None
 1.12A 5otrA-5nthA:
undetectable		 5otrA-5nthA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t65 METHYL-ACCEPTING
CHEMOTAXIS PROTEIN
PCTA

(Pseudomonas
aeruginosa) 		PF02743
(dCache_1) 		4 TYR A 129
VAL A 133
ASP A 131
ALA A 132
 None
 1.08A 5otrA-5t65A:
undetectable		 5otrA-5t65A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tqw INHIBITOR OF NUCLEAR
FACTOR KAPPA-B
KINASE SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 198
VAL A 202
PRO A 284
ALA A 189
 None
 1.06A 5otrA-5tqwA:
10.7		 5otrA-5tqwA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uz7 CALCITONIN RECEPTOR

(Homo sapiens) 		PF00002
(7tm_2) 		4 TYR R 234
VAL R 305
PRO R 270
ALA R 308
 None
 1.07A 5otrA-5uz7R:
undetectable		 5otrA-5uz7R:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v2d DIOXYGENASE

(Pseudomonas
brassicacearum) 		no annotation 4 TYR A  16
ASP A  48
PRO A  49
ALA A  46
 None
 1.10A 5otrA-5v2dA:
undetectable		 5otrA-5v2dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v91 FOSFOMYCIN
RESISTANCE PROTEIN

(Klebsiella
pneumoniae) 		PF00903
(Glyoxalase) 		4 VAL A  12
ASP A  52
PRO A  53
ALA A  11
 None
 1.10A 5otrA-5v91A:
undetectable		 5otrA-5v91A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1e PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Streptomyces
coelicolor) 		no annotation 4 VAL A 223
ASP A 225
PRO A 226
ALA A 232
 None
 0.66A 5otrA-5w1eA:
undetectable		 5otrA-5w1eA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5whs CATALASE-PEROXIDASE

(Neurospora
crassa) 		no annotation 4 VAL A 251
ASP A 395
PRO A 396
ALA A 254
 None
 1.06A 5otrA-5whsA:
undetectable		 5otrA-5whsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wii CONJUGAL TRANSFER
PROTEIN

(Escherichia
coli) 		no annotation 4 TYR A 106
VAL A 125
ASP A 121
ALA A 124
 None
 1.12A 5otrA-5wiiA:
undetectable		 5otrA-5wiiA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wy0 SMALL RNA
2'-O-METHYLTRANSFERA
SE

(Homo sapiens) 		no annotation 4 TYR A  81
VAL A  45
ASP A  23
ALA A  22
 None
None
SAM  A 800 ( 4.5A)
None
 1.13A 5otrA-5wy0A:
undetectable		 5otrA-5wy0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5k NETRIN RECEPTOR DCC

(Rattus
norvegicus) 		no annotation 4 TYR A 115
VAL A 134
ASP A  48
ALA A  49
 None
 1.10A 5otrA-5z5kA:
undetectable		 5otrA-5z5kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cer PYRUVATE
DEHYDROGENASE E1
COMPONENT SUBUNIT
ALPHA, SOMATIC FORM,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 4 TYR A 258
VAL A 281
ASP A 286
PRO A 287
 None
 1.08A 5otrA-6cerA:
undetectable		 5otrA-6cerA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f2d FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIP
FLAGELLAR
BIOSYNTHETIC PROTEIN
FLIQ

(Salmonella
enterica;
Salmonella
enterica) 		no annotation
no annotation 		4 TYR G  76
VAL G  16
PRO A 192
ALA G  13
 None
 1.03A 5otrA-6f2dG:
undetectable		 5otrA-6f2dG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gk6 -

(-) 		no annotation 4 TYR A  23
ASP A 325
PRO A 326
ALA A 322
 None
 1.08A 5otrA-6gk6A:
undetectable		 5otrA-6gk6A:
undetectable