SIMILAR PATTERNS OF AMINO ACIDS FOR 5OSR_A_ACTA402

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3h GUANOSINE
PENTAPHOSPHATE
SYNTHETASE

(Streptomyces
antibioticus) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03726
(PNPase) 		4 TYR A 133
VAL A  47
VAL A  70
ALA A 122
 SO4  A 903 (-3.8A)
None
None
None
 0.75A 5osrA-1e3hA:
undetectable		 5osrA-1e3hA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k32 TRICORN PROTEASE

(Thermoplasma
acidophilum) 		PF03572
(Peptidase_S41)
PF07676
(PD40)
PF14684
(Tricorn_C1)
PF14685
(Tricorn_PDZ) 		4 VAL A 367
ILE A 364
PRO A 359
ALA A 345
 None
 0.72A 5osrA-1k32A:
0.7		 5osrA-1k32A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kya LACCASE

(Trametes
versicolor) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.79A 5osrA-1kyaA:
undetectable		 5osrA-1kyaA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llu ALCOHOL
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 137
ILE A  91
VAL A  34
ALA A 132
 None
 0.62A 5osrA-1lluA:
0.0		 5osrA-1lluA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mz5 SIALIDASE

(Trypanosoma
rangeli) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 VAL A 603
ILE A 606
VAL A 548
ALA A 487
 None
 0.54A 5osrA-1mz5A:
0.3		 5osrA-1mz5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pix GLUTACONYL-COA
DECARBOXYLASE A
SUBUNIT

(Acidaminococcus
fermentans) 		PF01039
(Carboxyl_trans) 		4 TYR A 323
ILE A 411
VAL A 347
ALA A 362
 None
 0.74A 5osrA-1pixA:
0.1		 5osrA-1pixA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pxz MAJOR POLLEN
ALLERGEN JUN A 1

(Juniperus ashei) 		PF00544
(Pec_lyase_C) 		4 VAL A 158
ILE A 185
VAL A 116
ALA A 161
 None
 0.70A 5osrA-1pxzA:
undetectable		 5osrA-1pxzA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sef CONSERVED
HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF05899
(Cupin_3)
PF07883
(Cupin_2) 		4 VAL A  48
ILE A  50
VAL A 132
ALA A  67
 None
 0.52A 5osrA-1sefA:
undetectable		 5osrA-1sefA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ul1 FLAP ENDONUCLEASE-1

(Homo sapiens) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		4 TYR X  26
VAL X  31
ILE X  33
ALA X 176
 None
 0.68A 5osrA-1ul1X:
undetectable		 5osrA-1ul1X:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vyv CALCIUM CHANNEL
BETA-4SUBUNIT

(Rattus
norvegicus) 		PF00625
(Guanylate_kin)
PF12052
(VGCC_beta4Aa_N) 		4 VAL A 222
ILE A 315
VAL A 258
ALA A 312
 None
 0.73A 5osrA-1vyvA:
undetectable		 5osrA-1vyvA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwv DER F II

(Dermatophagoides
farinae) 		PF02221
(E1_DerP2_DerF2) 		4 VAL A  65
ILE A  63
VAL A 106
ALA A  56
 PE3  A1001 ( 4.0A)
None
PE3  A1001 ( 4.7A)
PE3  A1001 ( 4.1A)
 0.66A 5osrA-1xwvA:
undetectable		 5osrA-1xwvA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y3j COPPER-TRANSPORTING
ATPASE 1

(Homo sapiens) 		PF00403
(HMA) 		4 VAL A   9
ILE A   7
VAL A  36
ALA A  43
 None
 0.69A 5osrA-1y3jA:
undetectable		 5osrA-1y3jA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yvc MRR5

(Methanococcus
maripaludis) 		PF01938
(TRAM) 		4 VAL A  21
ILE A  23
VAL A  41
ALA A  34
 None
 0.72A 5osrA-1yvcA:
undetectable		 5osrA-1yvcA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yzs SULFIREDOXIN

(Homo sapiens) 		PF02195
(ParBc) 		4 VAL A  81
ILE A  79
VAL A  44
ALA A 115
 None
 0.54A 5osrA-1yzsA:
undetectable		 5osrA-1yzsA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2adc POLYPYRIMIDINE
TRACT-BINDING
PROTEIN 1

(Homo sapiens) 		PF00076
(RRM_1)
PF13893
(RRM_5) 		4 VAL A 367
ILE A 369
VAL A 341
ALA A 377
 None
 0.50A 5osrA-2adcA:
undetectable		 5osrA-2adcA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cpi CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT 4

(Mus musculus) 		PF00076
(RRM_1) 		4 VAL A 176
ILE A 173
VAL A 113
ALA A 188
 None
 0.70A 5osrA-2cpiA:
undetectable		 5osrA-2cpiA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e5y ATP SYNTHASE EPSILON
CHAIN

(Bacillus sp.
PS3) 		PF00401
(ATP-synt_DE)
PF02823
(ATP-synt_DE_N) 		4 VAL A  63
ILE A  61
VAL A  25
ALA A  50
 None
 0.71A 5osrA-2e5yA:
undetectable		 5osrA-2e5yA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4b SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		PF00076
(RRM_1) 		4 ILE A 191
VAL A 153
PRO A 157
ALA A 198
 None
 0.58A 5osrA-2g4bA:
undetectable		 5osrA-2g4bA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g4b SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		PF00076
(RRM_1) 		4 VAL A 189
ILE A 191
VAL A 153
ALA A 198
 None
 0.51A 5osrA-2g4bA:
undetectable		 5osrA-2g4bA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ge3 PROBABLE
ACETYLTRANSFERASE

(Agrobacterium
tumefaciens) 		PF00583
(Acetyltransf_1) 		4 TYR A  97
VAL A   8
ILE A  10
ALA A  63
 None
 0.75A 5osrA-2ge3A:
undetectable		 5osrA-2ge3A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4q THIOREDOXIN

(Mycobacterium
tuberculosis) 		PF00085
(Thioredoxin) 		4 VAL A  12
ILE A  10
VAL A  30
ALA A  61
 None
 0.59A 5osrA-2l4qA:
undetectable		 5osrA-2l4qA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ls0 ZOOCIN A
ENDOPEPTIDASE

(Streptococcus
equi) 		PF16775
(ZoocinA_TRD) 		4 TYR 1  24
VAL 1  38
VAL 1  60
ALA 1  57
 None
 0.77A 5osrA-2ls01:
undetectable		 5osrA-2ls01:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mtg LA-RELATED PROTEIN 6

(Homo sapiens) 		no annotation 4 VAL A 230
ILE A 232
VAL A 188
ALA A 259
 None
 0.69A 5osrA-2mtgA:
undetectable		 5osrA-2mtgA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7q BIFUNCTIONAL
3-DEHYDROQUINATE
DEHYDRATASE/SHIKIMAT
E DEHYDROGENASE

(Arabidopsis
thaliana) 		PF01487
(DHquinase_I)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 TYR A 509
VAL A 457
ILE A 459
ALA A 482
 None
 0.65A 5osrA-2o7qA:
undetectable		 5osrA-2o7qA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oas 4-HYDROXYBUTYRATE
COENZYME A
TRANSFERASE

(Shewanella
oneidensis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 VAL A 118
ILE A 116
VAL A 171
ALA A 148
 None
 0.76A 5osrA-2oasA:
undetectable		 5osrA-2oasA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pww UNCHARACTERIZED
PROTEIN

(Bacillus
clausii) 		PF08868
(YugN) 		4 VAL A  71
ILE A  73
VAL A  38
ALA A  57
 None
 0.58A 5osrA-2pwwA:
undetectable		 5osrA-2pwwA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q27 OXALYL-COA
DECARBOXYLASE

(Escherichia
coli) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 VAL A 467
ILE A 469
VAL A 392
ALA A 443
 None
 0.69A 5osrA-2q27A:
undetectable		 5osrA-2q27A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wji FERROUS IRON
TRANSPORT PROTEIN B
HOMOLOG

(Methanocaldococcus
jannaschii) 		PF02421
(FeoB_N) 		4 VAL A  86
ILE A  88
VAL A 142
ALA A 114
 None
 0.70A 5osrA-2wjiA:
undetectable		 5osrA-2wjiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyb LACCASE

(Trametes
cinnabarina) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.76A 5osrA-2xybA:
undetectable		 5osrA-2xybA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn1 LGPCA THIOREDOXIN

(synthetic
construct) 		PF00085
(Thioredoxin) 		4 VAL A   6
ILE A   4
VAL A  24
ALA A  55
 None
 0.68A 5osrA-2yn1A:
undetectable		 5osrA-2yn1A:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z06 PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0625

(Thermus
thermophilus) 		PF13277
(YmdB) 		4 VAL A   9
ILE A   6
VAL A  61
ALA A  34
 None
 0.72A 5osrA-2z06A:
undetectable		 5osrA-2z06A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a2k TRNA(ILE)-LYSIDINE
SYNTHASE

(Geobacillus
kaustophilus) 		PF01171
(ATP_bind_3)
PF09179
(TilS)
PF11734
(TilS_C) 		4 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
 0.69A 5osrA-3a2kA:
undetectable		 5osrA-3a2kA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b9n ALKANE MONOOXYGENASE

(Geobacillus
thermodenitrificans) 		PF00296
(Bac_luciferase) 		4 TYR A 365
ILE A 372
VAL A 251
ALA A 370
 None
 0.78A 5osrA-3b9nA:
undetectable		 5osrA-3b9nA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bfj 1,3-PROPANEDIOL
OXIDOREDUCTASE

(Klebsiella
pneumoniae) 		PF00465
(Fe-ADH) 		4 VAL A  97
ILE A  95
VAL A  66
ALA A  36
 None
 0.62A 5osrA-3bfjA:
undetectable		 5osrA-3bfjA:
21.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e3b CASEIN KINASE II
SUBUNIT ALPHA'

(Homo sapiens) 		PF00069
(Pkinase) 		5 TYR X  40
VAL X  68
ILE X  70
VAL X 102
ALA X 111
 None
 0.46A 5osrA-3e3bX:
46.1		 5osrA-3e3bX:
83.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fpl NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Clostridium
beijerinckii;
Thermoanaerobacter
brockii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 348
ILE A 350
VAL A  62
ALA A  33
 None
 0.65A 5osrA-3fplA:
undetectable		 5osrA-3fplA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h4x PHOSPHATIDYLINOSITOL
-SPECIFIC
PHOSPHOLIPASE C1

(Streptomyces
antibioticus) 		PF16670
(PI-PLC-C1) 		4 ILE A 194
VAL A 258
ASP A 260
ALA A 234
 None
None
EOH  A 358 (-4.1A)
None
 0.45A 5osrA-3h4xA:
undetectable		 5osrA-3h4xA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE

(Geobacillus
kaustophilus) 		PF11734
(TilS_C) 		4 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.74A 5osrA-3hj7A:
undetectable		 5osrA-3hj7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3il4 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 3

(Enterococcus
faecalis) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 TYR A 278
ILE A  50
VAL A  18
ASP A 164
 None
 0.68A 5osrA-3il4A:
undetectable		 5osrA-3il4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcm U4/U6 SMALL NUCLEAR
RIBONUCLEOPROTEIN
PRP4

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		4 TYR B 248
ILE B 224
VAL B 201
ALA B 191
 None
 0.75A 5osrA-3jcmB:
undetectable		 5osrA-3jcmB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l93 PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE

(Yersinia pestis) 		PF01467
(CTP_transf_like) 		4 VAL A  87
ILE A  85
VAL A  32
ALA A   5
 None
 0.47A 5osrA-3l93A:
undetectable		 5osrA-3l93A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lwb D-ALANINE--D-ALANINE
LIGASE

(Mycobacterium
tuberculosis) 		PF01820
(Dala_Dala_lig_N)
PF07478
(Dala_Dala_lig_C) 		4 VAL A  48
ILE A  46
VAL A 113
ALA A  14
 None
 0.66A 5osrA-3lwbA:
2.1		 5osrA-3lwbA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lxu TRIPEPTIDYL-PEPTIDAS
E 2

(Drosophila
melanogaster) 		PF00082
(Peptidase_S8)
PF12580
(TPPII)
PF12583
(TPPII_N) 		4 VAL X 864
ILE X 866
VAL X 822
ALA X 938
 None
 0.75A 5osrA-3lxuX:
undetectable		 5osrA-3lxuX:
13.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mc2 INHIBITOR OF
CARBONIC ANHYDRASE

(Mus musculus) 		PF00405
(Transferrin) 		4 VAL A 305
VAL A 250
PRO A 247
ALA A  82
 None
 0.65A 5osrA-3mc2A:
undetectable		 5osrA-3mc2A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mzh PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
CRP/FNR-FAMILY)

(Mycobacterium
tuberculosis) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		4 VAL A  55
ILE A  57
VAL A  37
ALA A  93
 None
CMP  A 623 ( 4.1A)
None
None
 0.69A 5osrA-3mzhA:
undetectable		 5osrA-3mzhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nfb BETA-PEPTIDYL
AMINOPEPTIDASE

(Sphingosinicella
xenopeptidilytica) 		PF03576
(Peptidase_S58) 		4 VAL A  52
ILE A  54
VAL A 131
ALA A  96
 None
 0.73A 5osrA-3nfbA:
undetectable		 5osrA-3nfbA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nut PRECORRIN-3
METHYLASE

(Rhodobacter
capsulatus) 		PF00590
(TP_methylase) 		4 VAL A 197
ILE A 204
VAL A 222
ALA A 194
 SAH  A1501 (-3.9A)
None
SAH  A1501 ( 4.2A)
None
 0.68A 5osrA-3nutA:
undetectable		 5osrA-3nutA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op1 MACROLIDE-EFFLUX
PROTEIN

(Streptococcus
pneumoniae) 		PF01687
(Flavokinase)
PF06574
(FAD_syn) 		4 VAL A 256
ILE A 258
VAL A 226
ALA A 237
 None
 0.67A 5osrA-3op1A:
undetectable		 5osrA-3op1A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owu STEROID
DELTA-ISOMERASE

(Pseudomonas
putida) 		PF12680
(SnoaL_2) 		4 VAL A  20
ILE A  17
VAL A  88
ALA A  68
 EQU  A 200 ( 4.9A)
None
None
None
 0.66A 5osrA-3owuA:
undetectable		 5osrA-3owuA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pea ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00378
(ECH_1) 		4 VAL A  50
ILE A  52
VAL A   7
ALA A  16
 None
 0.62A 5osrA-3peaA:
undetectable		 5osrA-3peaA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pk0 SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Mycolicibacterium
smegmatis) 		PF13561
(adh_short_C2) 		4 VAL A  61
ILE A  59
VAL A  10
ALA A  34
 None
 0.60A 5osrA-3pk0A:
undetectable		 5osrA-3pk0A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxl LACCASE

(Trametes
hirsuta) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.76A 5osrA-3pxlA:
undetectable		 5osrA-3pxlA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdk RIBULOKINASE

(Bacillus
halodurans) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 TYR A 528
VAL A 463
ILE A 459
ALA A 423
 None
 0.76A 5osrA-3qdkA:
undetectable		 5osrA-3qdkA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r75 ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I

(Burkholderia
lata) 		PF00117
(GATase)
PF00425
(Chorismate_bind) 		4 VAL A 362
ILE A 364
VAL A 196
ALA A 354
 None
 0.58A 5osrA-3r75A:
undetectable		 5osrA-3r75A:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rr2 CYSTEINE SYNTHASE

(Mycobacterium
marinum) 		PF00291
(PALP) 		4 VAL A 177
ILE A 183
VAL A 240
ALA A 201
 None
 0.76A 5osrA-3rr2A:
undetectable		 5osrA-3rr2A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syq G PROTEIN-ACTIVATED
INWARD RECTIFIER
POTASSIUM CHANNEL 2

(Mus musculus) 		PF01007
(IRK) 		4 VAL A 264
ILE A 262
VAL A 308
ALA A 241
 None
 0.77A 5osrA-3syqA:
undetectable		 5osrA-3syqA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6s CERJ

(Streptomyces
tendae) 		PF08541
(ACP_syn_III_C)
PF08545
(ACP_syn_III) 		4 VAL A 336
ILE A 338
VAL A   8
ALA A 180
 None
 0.65A 5osrA-3t6sA:
undetectable		 5osrA-3t6sA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 127
ASP A 129
PRO A 130
ALA A 104
 None
 0.77A 5osrA-3t6wA:
undetectable		 5osrA-3t6wA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ti8 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		4 VAL A 192
ILE A 194
VAL A 215
ALA A 203
 None
 0.75A 5osrA-3ti8A:
undetectable		 5osrA-3ti8A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uf6 LMO1369 PROTEIN

(Listeria
monocytogenes) 		PF01515
(PTA_PTB) 		4 TYR A 241
ILE A 122
VAL A 245
ALA A 250
 COD  A 289 (-4.1A)
None
None
None
 0.78A 5osrA-3uf6A:
undetectable		 5osrA-3uf6A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP

(Salmonella
enterica) 		PF00814
(Peptidase_M22) 		4 VAL B 145
ILE B 143
VAL B 264
ALA B 132
 None
 0.67A 5osrA-3zeuB:
undetectable		 5osrA-3zeuB:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a14 KINESIN-LIKE PROTEIN
KIF7

(Homo sapiens) 		PF00225
(Kinesin) 		4 VAL A 318
ILE A 320
VAL A  56
ALA A  16
 None
 0.66A 5osrA-4a14A:
undetectable		 5osrA-4a14A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3q ALANINE RACEMASE 1

(Staphylococcus
aureus) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 VAL A 251
VAL A 317
PRO A 320
ALA A 278
 None
 0.73A 5osrA-4a3qA:
undetectable		 5osrA-4a3qA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a9a RIBOSOME-INTERACTING
GTPASE 1

(Saccharomyces
cerevisiae) 		PF01926
(MMR_HSR1)
PF02824
(TGS)
PF16897
(MMR_HSR1_Xtn) 		4 VAL A 364
ILE A 366
VAL A 352
ALA A 338
 None
 0.52A 5osrA-4a9aA:
undetectable		 5osrA-4a9aA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bbm CYCLIN-DEPENDENT
KINASE-LIKE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 TYR A 179
VAL A 183
PRO A 272
ALA A 169
 None
 0.75A 5osrA-4bbmA:
25.2		 5osrA-4bbmA:
29.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bs2 TAR DNA-BINDING
PROTEIN 43

(Homo sapiens) 		PF00076
(RRM_1) 		4 VAL A 220
ILE A 222
VAL A 195
ALA A 230
 None
 0.72A 5osrA-4bs2A:
undetectable		 5osrA-4bs2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eex ALCOHOL
DEHYDROGENASE 1

(Lactococcus
lactis) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A  66
ILE A  69
VAL A 125
ALA A  29
 None
 0.75A 5osrA-4eexA:
undetectable		 5osrA-4eexA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fet SPORE CORTEX-LYTIC
ENZYME PREPEPTIDE

(Bacillus
anthracis) 		no annotation 4 TYR B 226
VAL B 166
PRO B 219
ALA B 223
 None
 0.79A 5osrA-4fetB:
undetectable		 5osrA-4fetB:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN

(Pseudomonas) 		PF01804
(Penicil_amidase) 		4 VAL B 197
VAL B 193
ASP B 177
ALA B 195
 None
 0.60A 5osrA-4hstB:
undetectable		 5osrA-4hstB:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lih GAMMA-GLUTAMYL-GAMMA
-AMINOBUTYRALDEHYDE
DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00171
(Aldedh) 		4 VAL A 236
ILE A 239
VAL A 189
ALA A 162
 None
 0.75A 5osrA-4lihA:
undetectable		 5osrA-4lihA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lmb CYSTEINE SYNTHASE

(Microcystis
aeruginosa) 		PF00291
(PALP) 		4 VAL A 180
ILE A 186
VAL A 243
ALA A 204
 PLP  A 403 (-3.9A)
None
None
None
 0.71A 5osrA-4lmbA:
undetectable		 5osrA-4lmbA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lza ADENINE
PHOSPHORIBOSYLTRANSF
ERASE

(Thermoanaerobacter
pseudethanolicus) 		PF00156
(Pribosyltran) 		4 VAL A 115
ILE A 117
VAL A  76
ALA A  54
 None
 0.56A 5osrA-4lzaA:
undetectable		 5osrA-4lzaA:
20.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4md8 CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		5 TYR E  39
VAL E  67
ILE E  69
VAL E 101
ALA E 110
 None
 0.16A 5osrA-4md8E:
49.7		 5osrA-4md8E:
94.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mh0 RAS-RELATED PROTEIN
RAP-1B

(Homo sapiens) 		PF00071
(Ras) 		4 VAL R 114
ILE R 112
VAL R   8
ALA R  79
 None
 0.65A 5osrA-4mh0R:
undetectable		 5osrA-4mh0R:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mou ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Paenarthrobacter
aurescens) 		PF00378
(ECH_1) 		4 VAL A  17
ILE A  19
VAL A  61
ALA A  24
 None
 0.64A 5osrA-4mouA:
undetectable		 5osrA-4mouA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n01 PERIPLASMIC BINDING
PROTEIN

(Veillonella
parvula) 		PF01497
(Peripla_BP_2) 		4 VAL A 147
ILE A 149
VAL A  64
ALA A 125
 None
 0.78A 5osrA-4n01A:
undetectable		 5osrA-4n01A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4noh LIPOPROTEIN,
PUTATIVE

(Bacillus
anthracis) 		PF17294
(Lipoprotein_22) 		4 VAL A  71
ILE A  73
VAL A 112
ALA A 147
 None
 0.62A 5osrA-4nohA:
undetectable		 5osrA-4nohA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4og1 ENOYL-COA
HYDRATASE/ISOMERASE

(Novosphingobium
aromaticivorans) 		PF00378
(ECH_1) 		4 VAL A  12
ILE A  14
VAL A  56
ALA A  19
 None
 0.58A 5osrA-4og1A:
undetectable		 5osrA-4og1A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p4g SHIKIMATE
5-DEHYDROGENASE AROE
(5-DEHYDROSHIKIMATE
REDUCTASE)

(Mycobacterium
tuberculosis) 		PF08501
(Shikimate_dh_N) 		4 VAL A 141
ILE A 144
VAL A 187
ALA A 120
 None
 0.49A 5osrA-4p4gA:
undetectable		 5osrA-4p4gA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qaw XYN30D

(Paenibacillus
barcinonensis) 		PF03422
(CBM_6)
PF17189
(Glyco_hydro_30C) 		4 VAL A 324
ILE A 326
VAL A 303
ALA A 317
 None
 0.78A 5osrA-4qawA:
undetectable		 5osrA-4qawA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsl PYRUVATE CARBOXYLASE

(Listeria
monocytogenes) 		no annotation 4 VAL H 106
ILE H 104
VAL H   7
ALA H  80
 None
 0.52A 5osrA-4qslH:
0.1		 5osrA-4qslH:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r81 NADH DEHYDROGENASE

(Methanothermobacter
marburgensis) 		PF02525
(Flavodoxin_2) 		4 VAL A   3
ILE A   5
VAL A 128
ALA A  83
 None
 0.52A 5osrA-4r81A:
undetectable		 5osrA-4r81A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4trr PUTATIVE
D-BETA-HYDROXYBUTYRA
TE DEHYDROGENASE

(Burkholderia
cenocepacia) 		PF00106
(adh_short) 		4 VAL A  60
ILE A  58
VAL A  10
ALA A  34
 None
 0.49A 5osrA-4trrA:
undetectable		 5osrA-4trrA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxt THIOREDOXIN

(Mycobacterium
avium) 		PF00085
(Thioredoxin) 		4 VAL A  13
ILE A  11
VAL A  31
ALA A  62
 None
 0.69A 5osrA-4wxtA:
undetectable		 5osrA-4wxtA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzz PUTATIVE SUGAR ABC
TRANSPORTER,
SUBSTRATE-BINDING
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF13407
(Peripla_BP_4) 		4 VAL A 108
ILE A 111
VAL A  84
ALA A  54
 None
 0.75A 5osrA-4wzzA:
undetectable		 5osrA-4wzzA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zw0 3-HYDROXYACYL-[ACYL-
CARRIER-PROTEIN]
DEHYDRATASE FABZ

(Candidatus
Liberibacter
asiaticus) 		PF07977
(FabA) 		4 VAL A  31
ILE A  34
VAL A 116
ALA A  40
 None
 0.64A 5osrA-4zw0A:
undetectable		 5osrA-4zw0A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a4j FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		4 VAL A 487
ILE A 489
VAL A 516
ALA A 527
 None
 0.70A 5osrA-5a4jA:
undetectable		 5osrA-5a4jA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a5g FORMATE--TETRAHYDROF
OLATE LIGASE

(Tepidanaerobacter
acetatoxydans) 		PF01268
(FTHFS) 		4 VAL A 489
ILE A 491
VAL A 518
ALA A 529
 None
 0.64A 5osrA-5a5gA:
undetectable		 5osrA-5a5gA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cxp POSSIBLE XYLAN
DEGRADATION ENZYME
(GLYCOSYL HYDROLASE
FAMILY 30-LIKE
DOMAIN AND RICIN
B-LIKE DOMAIN)

(Clostridium
acetobutylicum) 		PF02055
(Glyco_hydro_30) 		4 VAL A 322
ILE A 324
VAL A 301
ALA A 315
 None
 0.74A 5osrA-5cxpA:
undetectable		 5osrA-5cxpA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 126
ASP A 128
PRO A 129
ALA A 103
 None
 0.76A 5osrA-5ehfA:
undetectable		 5osrA-5ehfA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey5 LBCATS-A

(synthetic
construct) 		PF00290
(Trp_syntA) 		4 VAL A 210
ILE A 208
VAL A 226
ALA A 227
 None
 0.74A 5osrA-5ey5A:
undetectable		 5osrA-5ey5A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h7k ELONGATION FACTOR 2

(Pyrococcus
horikoshii) 		no annotation 4 VAL A 299
ILE A 302
VAL A 363
ALA A 312
 None
 0.72A 5osrA-5h7kA:
undetectable		 5osrA-5h7kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lp5 ROD
SHAPE-DETERMINING
PROTEIN (MREC)

(Helicobacter
pylori) 		PF04085
(MreC) 		4 VAL C 213
ILE C 216
VAL C 180
ALA C 225
 None
 0.70A 5osrA-5lp5C:
undetectable		 5osrA-5lp5C:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxr RNA-BINDING PROTEIN
7

(Homo sapiens) 		PF00076
(RRM_1) 		4 VAL A  39
ILE A  41
VAL A  14
ALA A  53
 None
 0.52A 5osrA-5lxrA:
undetectable		 5osrA-5lxrA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m22 HYDROQUINONE
DIOXYGENASE SMALL
SUBUNIT
HYDROQUINONE
DIOXYGENASE LARGE
SUBUNIT

(Sphingomonas
sp. TTNP3;
Sphingomonas
sp. TTNP3) 		no annotation
no annotation 		4 VAL A  19
ILE A  21
VAL B 277
ALA B 287
 None
 0.65A 5osrA-5m22A:
undetectable		 5osrA-5m22A:
17.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mov CASEIN KINASE II
SUBUNIT ALPHA

(Homo sapiens) 		PF00069
(Pkinase) 		7 TYR A  39
VAL A  67
ILE A  69
VAL A 101
ASP A 103
PRO A 104
ALA A 110
 None
 0.18A 5osrA-5movA:
51.6		 5osrA-5movA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0g SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		no annotation 4 VAL A 189
ILE A 191
PRO A 157
ALA A 198
 None
 0.51A 5osrA-5w0gA:
undetectable		 5osrA-5w0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w0g SPLICING FACTOR U2AF
65 KDA SUBUNIT

(Homo sapiens) 		no annotation 4 VAL A 189
ILE A 191
VAL A 153
ALA A 198
 None
 0.33A 5osrA-5w0gA:
undetectable		 5osrA-5w0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9w DNA MISMATCH REPAIR
PROTEIN MUTS

(Neisseria
gonorrhoeae) 		no annotation 4 VAL A 106
ILE A 109
VAL A  25
ALA A  87
 None
 0.59A 5osrA-5x9wA:
undetectable		 5osrA-5x9wA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME COMPLEX
EXONUCLEASE RRP44

(Homo sapiens) 		no annotation 4 VAL K 862
ILE K 864
VAL K 907
ALA K 850
 None
 0.75A 5osrA-6d6qK:
undetectable		 5osrA-6d6qK:
undetectable