SIMILAR PATTERNS OF AMINO ACIDS FOR 5OM2_B_DXTB501

	Hit	Macromolecule/ Organism	Pfam	Res.	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1as4	ANTICHYMOTRYPSIN (Homo sapiens)	PF00079 (Serpin)	5	VAL A  31 LEU A 272 ASP A 277 VAL B 375 ILE B 382	None	0.40A	5om2A-1as4A: 50.4 5om2B-1as4A: undetectable	5om2A-1as4A: 98.08 5om2B-1as4A: 9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1avb	ARCELIN-1 (Phaseolus vulgaris)	PF00139 (Lectin_legB)	5	VAL A 120 LEU A 167 ALA A 184 HIS A 181 ILE A 158	None	1.09A	5om2A-1avbA: 0.0 5om2B-1avbA: undetectable	5om2A-1avbA: 17.59 5om2B-1avbA: 11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1c8b	SPORE PROTEASE (Bacillus megaterium)	PF03418 (Peptidase_A25)	5	VAL A 649 LEU A 753 ALA A 750 VAL A 517 ILE A 591	None	1.19A	5om2A-1c8bA: 0.0 5om2B-1c8bA: undetectable	5om2A-1c8bA: 12.28 5om2B-1c8bA: 8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1cqq	TYPE 2 RHINOVIRUS 3C PROTEASE (Rhinovirus A)	PF00548 (Peptidase_C3)	5	VAL A 150 LEU A 174 PHE A 179 VAL A  36 ILE A 160	None	1.19A	5om2A-1cqqA: 0.0 5om2B-1cqqA: undetectable	5om2A-1cqqA: 17.84 5om2B-1cqqA: 12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dbw	TRANSCRIPTIONAL REGULATORY PROTEIN FIXJ (Sinorhizobium meliloti)	PF00072 (Response_reg)	5	LEU A  19 ALA A  20 VAL A  52 HIS A   7 ILE A  81	None	1.19A	5om2A-1dbwA: 0.0 5om2B-1dbwA: undetectable	5om2A-1dbwA: 20.61 5om2B-1dbwA: 15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dms	DMSO REDUCTASE (Rhodobacter capsulatus)	PF00384 (Molybdopterin) PF01568 (Molydop_binding)	5	LEU A 307 ALA A 308 PHE A 311 VAL A 182 ILE A 220	None None None None PGD  A 783 (-4.7A)	1.20A	5om2A-1dmsA: undetectable 5om2B-1dmsA: undetectable	5om2A-1dmsA: 7.22 5om2B-1dmsA: 4.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1dts	DETHIOBIOTIN SYNTHETASE (Escherichia coli)	PF13500 (AAA_26)	5	VAL A 173 LEU A  22 ALA A  21 VAL A   6 ILE A 142	None	1.17A	5om2A-1dtsA: 0.0 5om2B-1dtsA: undetectable	5om2A-1dtsA: 14.22 5om2B-1dtsA: 10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1e3d	[NIFE] HYDROGENASE SMALL SUBUNIT (Desulfovibrio desulfuricans)	PF01058 (Oxidored_q6) PF14720 (NiFe_hyd_SSU_C)	5	VAL A 109 LEU A 161 VAL A   9 HIS A  45 ILE A  71	None	1.03A	5om2A-1e3dA: 0.0 5om2B-1e3dA: undetectable	5om2A-1e3dA: 13.31 5om2B-1e3dA: 12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1e3e	ALCOHOL DEHYDROGENASE, CLASS II (Mus musculus)	PF00107 (ADH_zinc_N) PF08240 (ADH_N)	5	LEU A  21 ALA A  12 PHE A 150 VAL A  45 ILE A 361	None	1.21A	5om2A-1e3eA: 0.0 5om2B-1e3eA: undetectable	5om2A-1e3eA: 12.63 5om2B-1e3eA: 10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1eg7	FORMYLTETRAHYDROFOLA TE SYNTHETASE (Moorella thermoacetica)	PF01268 (FTHFS)	5	VAL A1426 LEU A1085 ALA A1084 VAL A1299 ILE A1060	None	1.20A	5om2A-1eg7A: undetectable 5om2B-1eg7A: undetectable	5om2A-1eg7A: 9.21 5om2B-1eg7A: 6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1gul	GLUTATHIONE TRANSFERASE A4-4 (Homo sapiens)	PF02798 (GST_N) PF14497 (GST_C_3)	5	VAL A  96 LEU A  72 ASP A  77 VAL A 158 ILE A 159	None	1.09A	5om2A-1gulA: undetectable 5om2B-1gulA: undetectable	5om2A-1gulA: 16.28 5om2B-1gulA: 12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1gxk	CHROMOSOME SEGREGATION SMC PROTEIN (Thermotoga maritima)	PF06470 (SMC_hinge)	5	VAL A 520 LEU A 538 PHE A 614 VAL A 600 ILE A 524	None	1.11A	5om2A-1gxkA: undetectable 5om2B-1gxkA: undetectable	5om2A-1gxkA: 18.33 5om2B-1gxkA: 16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1jeo	HYPOTHETICAL PROTEIN MJ1247 (Methanocaldococcus jannaschii)	PF01380 (SIS)	5	LEU A  62 ALA A  59 PHE A  58 VAL A 157 ILE A 161	None	1.21A	5om2A-1jeoA: undetectable 5om2B-1jeoA: undetectable	5om2A-1jeoA: 19.55 5om2B-1jeoA: 10.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1lwh	4-ALPHA-GLUCANOTRANS FERASE (Thermotoga maritima)	PF00128 (Alpha-amylase) PF09178 (DUF1945)	5	VAL A   8 LEU A  25 PHE A  79 VAL A  40 ILE A   6	None	1.17A	5om2A-1lwhA: undetectable 5om2B-1lwhA: undetectable	5om2A-1lwhA: 11.87 5om2B-1lwhA: 7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1nkq	HYPOTHETICAL 28.8 KDA PROTEIN IN PSD1-SKO1 INTERGENIC REGION (Saccharomyces cerevisiae)	PF01557 (FAA_hydrolase)	5	VAL A 109 LEU A 166 PHE A 170 VAL A 116 ILE A 113	None	1.10A	5om2A-1nkqA: undetectable 5om2B-1nkqA: undetectable	5om2A-1nkqA: 16.22 5om2B-1nkqA: 14.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1qmn	ALPHA-1-ANTICHYMOTRY PSIN (Homo sapiens)	PF00079 (Serpin)	5	VAL A  31 LEU A 272 ASP A 277 VAL A 379 ILE A 386	None	0.52A	5om2A-1qmnA: 37.4 5om2B-1qmnA: undetectable	5om2A-1qmnA: 85.00 5om2B-1qmnA: 9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1qu9	YJGF PROTEIN (Escherichia coli)	PF01042 (Ribonuc_L-PSP)	5	VAL A  46 ALA A  85 PHE A  84 VAL A  78 ILE A 119	None None CSP  A 107 ( 3.5A) None None	1.13A	5om2A-1qu9A: undetectable 5om2B-1qu9A: undetectable	5om2A-1qu9A: 17.83 5om2B-1qu9A: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1sfe	ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE (Escherichia coli)	PF01035 (DNA_binding_1) PF02870 (Methyltransf_1N)	5	VAL A 143 LEU A  78 VAL A  28 HIS A  70 ILE A  38	None	1.21A	5om2A-1sfeA: undetectable 5om2B-1sfeA: undetectable	5om2A-1sfeA: 18.54 5om2B-1sfeA: 14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1suv	TRANSFERRIN RECEPTOR PROTEIN 1 (Homo sapiens)	PF02225 (PA) PF04253 (TFR_dimer) PF04389 (Peptidase_M28)	5	LEU A 429 ALA A 430 PHE A 433 VAL A 598 ILE A 482	None	1.03A	5om2A-1suvA: undetectable 5om2B-1suvA: undetectable	5om2A-1suvA: 8.06 5om2B-1suvA: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1suv	TRANSFERRIN RECEPTOR PROTEIN 1 (Homo sapiens)	PF02225 (PA) PF04253 (TFR_dimer) PF04389 (Peptidase_M28)	5	VAL A 405 LEU A 429 ALA A 430 PHE A 433 ILE A 482	None	1.10A	5om2A-1suvA: undetectable 5om2B-1suvA: undetectable	5om2A-1suvA: 8.06 5om2B-1suvA: 5.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1tis	THYMIDYLATE SYNTHASE (Escherichia virus T4)	PF00303 (Thymidylat_synt)	5	VAL A 261 LEU A  63 ASP A 120 VAL A 198 ILE A 197	None	0.89A	5om2A-1tisA: undetectable 5om2B-1tisA: undetectable	5om2A-1tisA: 13.19 5om2B-1tisA: 9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1vr0	PROBABLE 2-PHOSPHOSULFOLACTAT E PHOSPHATASE (Clostridium acetobutylicum)	PF04029 (2-ph_phosp)	5	VAL A 123 PHE A 214 VAL A 196 HIS A 201 ILE A 192	None None None 3SL  A 300 (-4.6A) None	1.19A	5om2A-1vr0A: undetectable 5om2B-1vr0A: undetectable	5om2A-1vr0A: 17.77 5om2B-1vr0A: 11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1w93	ACETYL-COENZYME A CARBOXYLASE (Saccharomyces cerevisiae)	PF00289 (Biotin_carb_N) PF02785 (Biotin_carb_C) PF02786 (CPSase_L_D2)	5	VAL A  92 LEU A 404 ALA A 401 HIS A  53 ILE A  59	None	1.21A	5om2A-1w93A: undetectable 5om2B-1w93A: undetectable	5om2A-1w93A: 8.64 5om2B-1w93A: 5.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1yq2	BETA-GALACTOSIDASE (Arthrobacter sp. C2-2)	PF02836 (Glyco_hydro_2_C) PF02837 (Glyco_hydro_2_N) PF02929 (Bgal_small_N) PF16353 (DUF4981)	5	LEU A 141 PHE A 143 ASP A 144 VAL A 152 ILE A 159	None	1.11A	5om2A-1yq2A: undetectable 5om2B-1yq2A: undetectable	5om2A-1yq2A: 6.65 5om2B-1yq2A: 3.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2be3	GTP PYROPHOSPHOKINASE (Streptococcus pneumoniae)	PF04607 (RelA_SpoT)	5	VAL A 121 LEU A  93 ASP A  98 VAL A  78 ILE A 142	None	1.20A	5om2A-2be3A: undetectable 5om2B-2be3A: undetectable	5om2A-2be3A: 16.97 5om2B-2be3A: 10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2bsz	ARYLAMINE N-ACETYLTRANSFERASE 1 (Mesorhizobium loti)	PF00797 (Acetyltransf_2)	5	VAL A 268 LEU A 246 ALA A 247 VAL A 208 ILE A 273	None	1.08A	5om2A-2bszA: undetectable 5om2B-2bszA: undetectable	5om2A-2bszA: 13.21 5om2B-2bszA: 9.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2de2	DIBENZOTHIOPHENE DESULFURIZATION ENZYME B (Rhodococcus sp. IGTS8)	no annotation	5	VAL A 124 LEU A 160 ALA A 157 VAL A 174 ILE A 122	None	1.11A	5om2A-2de2A: undetectable 5om2B-2de2A: undetectable	5om2A-2de2A: 10.68 5om2B-2de2A: 5.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2e5v	L-ASPARTATE OXIDASE (Sulfurisphaera tokodaii)	PF00890 (FAD_binding_2) PF02910 (Succ_DH_flav_C)	5	VAL A  25 LEU A  18 ASP A 369 VAL A 169 ILE A   4	None	1.06A	5om2A-2e5vA: undetectable 5om2B-2e5vA: undetectable	5om2A-2e5vA: 9.52 5om2B-2e5vA: 6.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ebd	3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE 3 (Aquifex aeolicus)	PF08541 (ACP_syn_III_C) PF08545 (ACP_syn_III)	5	VAL A 165 LEU A 118 ALA A 117 PHE A 114 ILE A   5	None	1.20A	5om2A-2ebdA: undetectable 5om2B-2ebdA: undetectable	5om2A-2ebdA: 14.62 5om2B-2ebdA: 10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2fcj	SMALL TOPRIM DOMAIN PROTEIN (Geobacillus stearothermophilus)	PF01751 (Toprim)	5	VAL A  30 LEU A  44 PHE A  74 VAL A  53 HIS A  79	None	1.06A	5om2A-2fcjA: undetectable 5om2B-2fcjA: undetectable	5om2A-2fcjA: 20.16 5om2B-2fcjA: 10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2gzl	2-C-METHYL-D-ERYTHRI TOL 2,4-CYCLODIPHOSPHATE SYNTHASE (Escherichia coli)	PF02542 (YgbB)	5	VAL A  39 LEU A  31 ALA A  11 PHE A  12 ILE A  20	None	1.02A	5om2A-2gzlA: undetectable 5om2B-2gzlA: undetectable	5om2A-2gzlA: 23.48 5om2B-2gzlA: 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2h6t	CANDIDAPEPSIN-3 (Candida albicans)	PF00026 (Asp)	5	LEU A 327 ALA A 270 PHE A 266 HIS A 197 ILE A 325	None None None ZN  A 602 (-3.1A) None	1.12A	5om2A-2h6tA: undetectable 5om2B-2h6tA: undetectable	5om2A-2h6tA: 12.94 5om2B-2h6tA: 7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2nvo	RO SIXTY-RELATED PROTEIN, RSR (Deinococcus radiodurans)	PF05731 (TROVE)	5	LEU A 313 ALA A 517 PHE A 515 ASP A 516 ILE A 395	None	1.13A	5om2A-2nvoA: undetectable 5om2B-2nvoA: undetectable	5om2A-2nvoA: 10.15 5om2B-2nvoA: 5.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2qul	D-TAGATOSE 3-EPIMERASE (Pseudomonas cichorii)	PF01261 (AP_endonuc_2)	5	VAL A 175 ALA A 131 PHE A  75 VAL A 138 ILE A 139	None	1.07A	5om2A-2qulA: undetectable 5om2B-2qulA: undetectable	5om2A-2qulA: 14.83 5om2B-2qulA: 9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2vn7	GLUCOAMYLASE (Trichoderma reesei)	PF00686 (CBM_20) PF00723 (Glyco_hydro_15)	5	VAL A 159 LEU A 202 ALA A 203 VAL A 151 ILE A 155	None	1.09A	5om2A-2vn7A: undetectable 5om2B-2vn7A: undetectable	5om2A-2vn7A: 8.42 5om2B-2vn7A: 5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xry	DEOXYRIBODIPYRIMIDIN E PHOTOLYASE (Methanosarcina mazei)	PF00875 (DNA_photolyase)	5	VAL A 105 LEU A 113 PHE A 138 VAL A 130 ILE A 101	None	1.20A	5om2A-2xryA: undetectable 5om2B-2xryA: undetectable	5om2A-2xryA: 13.97 5om2B-2xryA: 6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2xsj	SULFITE REDUCTASE ALPHA SUBUNIT (Desulfomicrobium norvegicum)	PF01077 (NIR_SIR) PF03460 (NIR_SIR_ferr)	5	VAL A 351 LEU A 193 ALA A 190 PHE A 218 ILE A 358	None	1.08A	5om2A-2xsjA: undetectable 5om2B-2xsjA: undetectable	5om2A-2xsjA: 11.21 5om2B-2xsjA: 6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3a28	L-2.3-BUTANEDIOL DEHYDROGENASE (Corynebacterium glutamicum)	no annotation	5	VAL C   7 LEU C  22 ALA C  23 PHE C  27 VAL C  84	None	1.12A	5om2A-3a28C: undetectable 5om2B-3a28C: undetectable	5om2A-3a28C: 16.33 5om2B-3a28C: 9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3b05	ISOPENTENYL-DIPHOSPH ATE DELTA-ISOMERASE (Sulfolobus shibatae)	PF01070 (FMN_dh)	5	LEU A 176 ALA A 175 VAL A 192 HIS A 155 ILE A 212	None None None IPE  A 701 ( 3.4A) None	1.22A	5om2A-3b05A: undetectable 5om2B-3b05A: undetectable	5om2A-3b05A: 11.17 5om2B-3b05A: 8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3cbt	PHOSPHATASE SC4828 (Streptomyces coelicolor)	PF04167 (DUF402)	5	VAL A 145 LEU A  59 ALA A 109 VAL A  49 ILE A  31	VAL  A 145 ( 0.6A) LEU  A  59 ( 0.6A) ALA  A 109 (-0.0A) VAL  A  49 ( 0.6A) ILE  A  31 ( 0.6A)	1.08A	5om2A-3cbtA: undetectable 5om2B-3cbtA: undetectable	5om2A-3cbtA: 15.32 5om2B-3cbtA: 11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3cmg	PUTATIVE BETA-GALACTOSIDASE (Bacteroides fragilis)	PF00703 (Glyco_hydro_2) PF02836 (Glyco_hydro_2_C) PF02837 (Glyco_hydro_2_N) PF16355 (DUF4982)	5	LEU A 104 PHE A 106 VAL A 115 HIS A 125 ILE A 122	None	1.06A	5om2A-3cmgA: undetectable 5om2B-3cmgA: undetectable	5om2A-3cmgA: 9.65 5om2B-3cmgA: 5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ec1	YQEH GTPASE (Geobacillus stearothermophilus)	PF01926 (MMR_HSR1)	5	VAL A 362 ALA A 265 PHE A 261 VAL A 343 ILE A 335	None	1.03A	5om2A-3ec1A: undetectable 5om2B-3ec1A: undetectable	5om2A-3ec1A: 12.47 5om2B-3ec1A: 7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3fz0	NUCLEOSIDE HYDROLASE, PUTATIVE (Trypanosoma brucei)	PF01156 (IU_nuc_hydro)	5	LEU A 349 ALA A 348 PHE A 345 VAL A 278 ILE A  18	None	1.15A	5om2A-3fz0A: undetectable 5om2B-3fz0A: undetectable	5om2A-3fz0A: 12.32 5om2B-3fz0A: 7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3igz	COFACTOR-INDEPENDENT PHOSPHOGLYCERATE MUTASE (Leishmania mexicana)	PF01676 (Metalloenzyme) PF06415 (iPGM_N)	5	VAL B  20 LEU B 450 ASP B 455 VAL B 417 ILE B 419	None	1.17A	5om2A-3igzB: undetectable 5om2B-3igzB: undetectable	5om2A-3igzB: 7.49 5om2B-3igzB: 7.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ihm	STYRENE MONOOXYGENASE A (Pseudomonas putida)	no annotation	5	VAL A 140 LEU A  17 ALA A  13 VAL A  28 ILE A   5	None	1.15A	5om2A-3ihmA: undetectable 5om2B-3ihmA: undetectable	5om2A-3ihmA: 13.90 5om2B-3ihmA: 6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3il4	3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE 3 (Enterococcus faecalis)	PF08541 (ACP_syn_III_C) PF08545 (ACP_syn_III)	5	LEU A 124 ALA A 123 PHE A 120 VAL A 169 ILE A 171	None None None CSO  A  13 ( 3.6A) None	1.18A	5om2A-3il4A: undetectable 5om2B-3il4A: undetectable	5om2A-3il4A: 12.10 5om2B-3il4A: 11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ilr	HEPARIN LYASE I (Bacteroides thetaiotaomicron)	PF14099 (Polysacc_lyase)	5	LEU A 229 ALA A 230 PHE A 231 VAL A 297 ILE A 299	None SGN  A 377 ( 3.9A) None None None	1.08A	5om2A-3ilrA: undetectable 5om2B-3ilrA: undetectable	5om2A-3ilrA: 12.22 5om2B-3ilrA: 6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3izq	ELONGATION FACTOR 1 ALPHA-LIKE PROTEIN (Saccharomyces cerevisiae)	PF00009 (GTP_EFTU) PF03143 (GTP_EFTU_D3) PF08938 (HBS1_N)	5	ALA 1 178 ASP 1 177 VAL 1 172 HIS 1 296 ILE 1 273	None	1.21A	5om2A-3izq1: undetectable 5om2B-3izq1: undetectable	5om2A-3izq1: 10.17 5om2B-3izq1: 7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3juy	3B3 SINGLE CHAIN VARIANT HIV-1 ANTIBODY (Homo sapiens)	no annotation	5	LEU B 247 ALA B 227 PHE B 226 VAL B 221 ILE B 218	None	1.21A	5om2A-3juyB: undetectable 5om2B-3juyB: undetectable	5om2A-3juyB: 16.13 5om2B-3juyB: 8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3k28	GLUTAMATE-1-SEMIALDE HYDE 2,1-AMINOMUTASE 2 (Bacillus anthracis)	PF00202 (Aminotran_3)	5	VAL A 112 LEU A 266 PHE A 246 VAL A 106 ILE A 109	None None None None CA  A 430 (-4.9A)	1.19A	5om2A-3k28A: undetectable 5om2B-3k28A: undetectable	5om2A-3k28A: 9.77 5om2B-3k28A: 7.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3kzw	CYTOSOL AMINOPEPTIDASE (Staphylococcus aureus)	PF00883 (Peptidase_M17) PF02789 (Peptidase_M17_N)	5	VAL A 210 ALA A 196 PHE A 195 VAL A 290 ILE A 242	None	1.12A	5om2A-3kzwA: undetectable 5om2B-3kzwA: undetectable	5om2A-3kzwA: 10.98 5om2B-3kzwA: 6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ojl	CAP5O (Staphylococcus aureus)	PF00984 (UDPG_MGDP_dh) PF03720 (UDPG_MGDP_dh_C) PF03721 (UDPG_MGDP_dh_N)	5	LEU A 379 PHE A 384 ASP A 381 VAL A 367 ILE A 369	None	1.10A	5om2A-3ojlA: undetectable 5om2B-3ojlA: undetectable	5om2A-3ojlA: 13.05 5om2B-3ojlA: 8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ozx	RNASE L INHIBITOR (Sulfolobus solfataricus)	PF00005 (ABC_tran)	5	LEU A 388 ALA A 385 ASP A 484 VAL A 360 ILE A 349	None None MG  A 613 ( 3.9A) None None	1.17A	5om2A-3ozxA: undetectable 5om2B-3ozxA: undetectable	5om2A-3ozxA: 9.11 5om2B-3ozxA: 6.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pdw	UNCHARACTERIZED HYDROLASE YUTF (Bacillus subtilis)	PF13242 (Hydrolase_like) PF13344 (Hydrolase_6)	5	LEU A 251 VAL A 206 HIS A 246 TRP A 254 ILE A  11	None None None ACY  A 269 ( 4.5A) None	1.20A	5om2A-3pdwA: undetectable 5om2B-3pdwA: undetectable	5om2A-3pdwA: 14.39 5om2B-3pdwA: 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pfr	MANDELATE RACEMASE/MUCONATE LACTONIZING PROTEIN (Actinobacillus succinogenes)	PF02746 (MR_MLE_N) PF13378 (MR_MLE_C)	5	LEU A 349 ALA A 350 PHE A 352 VAL A 148 ILE A 386	None	1.12A	5om2A-3pfrA: undetectable 5om2B-3pfrA: undetectable	5om2A-3pfrA: 10.33 5om2B-3pfrA: 6.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3pl1	PYRAZINAMIDASE/NICOT INAMIDASE PNCA (PZASE) (Mycobacterium tuberculosis)	PF00857 (Isochorismatase)	5	VAL A  44 LEU A  35 ALA A  39 VAL A 131 ILE A   6	None	1.21A	5om2A-3pl1A: undetectable 5om2B-3pl1A: undetectable	5om2A-3pl1A: 17.44 5om2B-3pl1A: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3qxi	ENOYL-COA HYDRATASE ECHA1 (Mycobacterium marinum)	PF00378 (ECH_1)	5	VAL A  12 LEU A  42 ALA A  43 VAL A  34 ILE A  25	None	1.20A	5om2A-3qxiA: undetectable 5om2B-3qxiA: undetectable	5om2A-3qxiA: 13.43 5om2B-3qxiA: 10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3r20	CYTIDYLATE KINASE (Mycolicibacterium smegmatis)	PF02224 (Cytidylate_kin)	5	VAL A  10 LEU A  25 ALA A  26 VAL A 144 ILE A 146	None	1.00A	5om2A-3r20A: undetectable 5om2B-3r20A: undetectable	5om2A-3r20A: 15.35 5om2B-3r20A: 9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3r8c	CYTIDYLATE KINASE (Mycobacteroides abscessus)	PF02224 (Cytidylate_kin)	5	VAL A   4 LEU A  19 ALA A  20 VAL A 138 ILE A 140	None	1.09A	5om2A-3r8cA: undetectable 5om2B-3r8cA: undetectable	5om2A-3r8cA: 15.62 5om2B-3r8cA: 9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3u4c	BACILYSIN BIOSYNTHESIS OXIDOREDUCTASE YWFH (Bacillus subtilis)	PF13561 (adh_short_C2)	6	VAL A   8 LEU A  23 ALA A  24 PHE A  28 VAL A  85 ILE A  87	None	1.28A	5om2A-3u4cA: undetectable 5om2B-3u4cA: undetectable	5om2A-3u4cA: 18.49 5om2B-3u4cA: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3u7j	RIBOSE-5-PHOSPHATE ISOMERASE A (Burkholderia thailandensis)	PF06026 (Rib_5-P_isom_A)	5	VAL A  22 LEU A  47 ALA A  46 VAL A  34 ILE A  32	None	1.11A	5om2A-3u7jA: undetectable 5om2B-3u7jA: undetectable	5om2A-3u7jA: 13.50 5om2B-3u7jA: 12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3vzq	ACETOACETYL-COA REDUCTASE (Cupriavidus necator)	PF00106 (adh_short)	5	LEU A  23 ALA A  24 PHE A  28 VAL A  84 ILE A  86	None	1.08A	5om2A-3vzqA: undetectable 5om2B-3vzqA: undetectable	5om2A-3vzqA: 17.12 5om2B-3vzqA: 15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3w1e	FLAGELLA BASAL-BODY PROTEIN (Vibrio alginolyticus)	PF16538 (FlgT_C) PF16539 (FlgT_M) PF16548 (FlgT_N)	5	VAL A 175 LEU A 199 ALA A 198 PHE A 197 ILE A 106	None	1.17A	5om2A-3w1eA: undetectable 5om2B-3w1eA: undetectable	5om2A-3w1eA: 10.83 5om2B-3w1eA: 9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4cr4	26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG (Saccharomyces cerevisiae)	PF00004 (AAA)	5	VAL K 274 LEU K 299 ASP K 304 VAL K 314 ILE K 271	None	0.85A	5om2A-4cr4K: undetectable 5om2B-4cr4K: undetectable	5om2A-4cr4K: 11.90 5om2B-4cr4K: 6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4eco	UNCHARACTERIZED PROTEIN (Bacteroides eggerthii)	no annotation	5	LEU A 380 ALA A 379 PHE A 479 VAL A 470 ILE A 369	None	0.99A	5om2A-4ecoA: undetectable 5om2B-4ecoA: undetectable	5om2A-4ecoA: 11.09 5om2B-4ecoA: 4.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4fid	G PROTEIN ALPHA SUBUNIT (Entamoeba histolytica)	PF00503 (G-alpha)	5	LEU A  43 PHE A 174 VAL A  26 HIS A 182 ILE A 207	None	1.19A	5om2A-4fidA: undetectable 5om2B-4fidA: undetectable	5om2A-4fidA: 13.31 5om2B-4fidA: 9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4gi2	CROTONYL-COA CARBOXYLASE/REDUCTAS E (Methylobacterium extorquens)	PF00107 (ADH_zinc_N) PF08240 (ADH_N)	5	VAL A 329 LEU A 200 ALA A 196 VAL A 214 ILE A 305	None	1.21A	5om2A-4gi2A: undetectable 5om2B-4gi2A: undetectable	5om2A-4gi2A: 9.93 5om2B-4gi2A: 8.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4h1s	5'-NUCLEOTIDASE (Homo sapiens)	PF00149 (Metallophos) PF02872 (5_nucleotid_C)	5	LEU A 127 PHE A 120 ASP A 121 HIS A 220 ILE A 139	None None None ZN  A 602 (-3.3A) None	1.21A	5om2A-4h1sA: undetectable 5om2B-4h1sA: undetectable	5om2A-4h1sA: 9.25 5om2B-4h1sA: 8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4hci	CUPREDOXIN 1 (Bacillus anthracis)	PF13473 (Cupredoxin_1)	5	VAL A 102 LEU A  69 PHE A  81 VAL A 126 ILE A  61	None	1.15A	5om2A-4hciA: undetectable 5om2B-4hciA: undetectable	5om2A-4hciA: 18.75 5om2B-4hciA: 15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4iig	BETA-GLUCOSIDASE 1 (Aspergillus aculeatus)	PF00933 (Glyco_hydro_3) PF01915 (Glyco_hydro_3_C) PF14310 (Fn3-like)	5	LEU A 856 ALA A 855 VAL A 765 HIS A 663 ILE A 763	None	1.16A	5om2A-4iigA: undetectable 5om2B-4iigA: undetectable	5om2A-4iigA: 6.49 5om2B-4iigA: 4.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4jpd	PROTEIN CYAY (Burkholderia cenocepacia)	PF01491 (Frataxin_Cyay)	5	LEU A  92 ALA A  91 PHE A  88 VAL A  52 ILE A  50	None	1.12A	5om2A-4jpdA: undetectable 5om2B-4jpdA: undetectable	5om2A-4jpdA: 19.67 5om2B-4jpdA: 15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4lan	URACIL-5-CARBOXYLATE DECARBOXYLASE (Cordyceps militaris)	PF04909 (Amidohydro_2)	5	VAL A 153 LEU A 137 ALA A 136 VAL A 185 ILE A 150	None	1.17A	5om2A-4lanA: undetectable 5om2B-4lanA: undetectable	5om2A-4lanA: 12.26 5om2B-4lanA: 8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4nhd	3-OXOACYL-[ACYL-CARR IER-PROTEIN] SYNTHASE 3 PROTEIN 1 (Vibrio cholerae)	PF08541 (ACP_syn_III_C) PF08545 (ACP_syn_III)	5	VAL A 166 LEU A 119 ALA A 118 PHE A 115 ILE A   5	None	1.15A	5om2A-4nhdA: undetectable 5om2B-4nhdA: undetectable	5om2A-4nhdA: 13.64 5om2B-4nhdA: 12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4r7f	UNCHARACTERIZED PROTEIN (Parabacteroides merdae)	PF17116 (DUF5103)	5	LEU A 124 PHE A 131 VAL A  78 HIS A  80 ILE A 139	None	1.17A	5om2A-4r7fA: undetectable 5om2B-4r7fA: undetectable	5om2A-4r7fA: 12.75 5om2B-4r7fA: 6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4r7v	ARRESTIN DOMAIN-CONTAINING PROTEIN 3 (Homo sapiens)	PF00339 (Arrestin_N)	5	VAL A   6 LEU A  36 VAL A  44 HIS A 143 ILE A  42	None	0.86A	5om2A-4r7vA: undetectable 5om2B-4r7vA: undetectable	5om2A-4r7vA: 17.61 5om2B-4r7vA: 8.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4r7x	ARRESTIN DOMAIN-CONTAINING PROTEIN 3 (Homo sapiens)	PF00339 (Arrestin_N)	5	VAL A   6 LEU A  36 VAL A  44 HIS A 143 ILE A  42	None None None PO4  A 204 ( 3.9A) None	0.74A	5om2A-4r7xA: undetectable 5om2B-4r7xA: undetectable	5om2A-4r7xA: 17.93 5om2B-4r7xA: 9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4rf7	ARGININE KINASE (Anthopleura japonica)	PF00217 (ATP-gua_Ptrans) PF02807 (ATP-gua_PtransN)	5	VAL A 641 LEU A 707 ALA A 646 PHE A 652 ILE A 683	None	1.21A	5om2A-4rf7A: undetectable 5om2B-4rf7A: undetectable	5om2A-4rf7A: 7.67 5om2B-4rf7A: 4.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ug4	CHOLINE SULFATASE (Sinorhizobium meliloti)	PF00884 (Sulfatase) PF12411 (Choline_sulf_C)	5	VAL A 273 LEU A  34 VAL A  13 HIS A 199 ILE A  11	None	1.18A	5om2A-4ug4A: undetectable 5om2B-4ug4A: undetectable	5om2A-4ug4A: 11.02 5om2B-4ug4A: 5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ui9	CELL DIVISION CYCLE PROTEIN 23 HOMOLOG (Homo sapiens)	PF04049 (ANAPC8) PF13181 (TPR_8) PF13414 (TPR_11)	5	LEU C 405 ALA C 401 ASP C 398 HIS C 390 ILE C 385	None	1.16A	5om2A-4ui9C: undetectable 5om2B-4ui9C: undetectable	5om2A-4ui9C: 9.20 5om2B-4ui9C: 6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4uqf	GTP CYCLOHYDROLASE 1 (Listeria monocytogenes)	PF01227 (GTP_cyclohydroI)	5	VAL A  69 LEU A 106 ALA A 107 ASP A 111 VAL A 142	None	0.86A	5om2A-4uqfA: undetectable 5om2B-4uqfA: undetectable	5om2A-4uqfA: 21.36 5om2B-4uqfA: 9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4xgn	3-HYDROXYACYL-COA DEHYDROGENASE (Burkholderia thailandensis)	PF00106 (adh_short)	5	VAL A  32 LEU A  25 PHE A 231 VAL A  81 ILE A  10	None	1.17A	5om2A-4xgnA: undetectable 5om2B-4xgnA: undetectable	5om2A-4xgnA: 18.18 5om2B-4xgnA: 10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4xny	LIGHT CHAIN OF ANTIBODY VRC08C (Homo sapiens)	PF07654 (C1-set) PF07686 (V-set)	5	LEU L 104 ALA L  84 PHE L  83 VAL L  78 ILE L  75	None	1.21A	5om2A-4xnyL: undetectable 5om2B-4xnyL: undetectable	5om2A-4xnyL: 15.76 5om2B-4xnyL: 12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4y7v	NUCLEOTIDYL TRANSFERASE (Pseudomonas putida)	PF00483 (NTP_transferase)	5	VAL A  49 LEU A  41 PHE A 114 VAL A 104 ILE A   5	None	1.15A	5om2A-4y7vA: undetectable 5om2B-4y7vA: undetectable	5om2A-4y7vA: 16.88 5om2B-4y7vA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4yuf	CORB (Corallococcus coralloides)	PF08541 (ACP_syn_III_C) PF08545 (ACP_syn_III)	5	VAL A 175 LEU A 128 ALA A 127 PHE A 124 ILE A  13	None	0.94A	5om2A-4yufA: undetectable 5om2B-4yufA: undetectable	5om2A-4yufA: 13.77 5om2B-4yufA: 9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5c7i	GLYCERALDEHYDE-3-PHO SPHATE DEHYDROGENASE, TESTIS-SPECIFIC (Mus musculus)	PF00044 (Gp_dh_N) PF02800 (Gp_dh_C)	5	VAL O 136 LEU O 123 PHE O 150 VAL O 172 ILE O 177	None	1.21A	5om2A-5c7iO: undetectable 5om2B-5c7iO: undetectable	5om2A-5c7iO: 12.62 5om2B-5c7iO: 9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5cbm	M17 FAMILY AMINOPEPTIDASE (Plasmodium falciparum)	PF00883 (Peptidase_M17)	5	VAL A 190 LEU A 210 PHE A 238 VAL A 224 ILE A 129	None	1.13A	5om2A-5cbmA: undetectable 5om2B-5cbmA: undetectable	5om2A-5cbmA: 8.48 5om2B-5cbmA: 6.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5dmy	BETA-GALACTOSIDASE (Bifidobacterium bifidum)	PF00703 (Glyco_hydro_2) PF02836 (Glyco_hydro_2_C) PF02837 (Glyco_hydro_2_N) PF16355 (DUF4982)	5	LEU A 368 ALA A 365 ASP A 112 VAL A 379 ILE A 357	None	1.16A	5om2A-5dmyA: undetectable 5om2B-5dmyA: undetectable	5om2A-5dmyA: 6.80 5om2B-5dmyA: 3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5h7w	VENOM 5'-NUCLEOTIDASE (Naja atra)	no annotation	5	LEU A 127 PHE A 120 ASP A 121 HIS A 220 ILE A 139	None None None ZN  A 606 (-3.1A) None	1.17A	5om2A-5h7wA: undetectable 5om2B-5h7wA: undetectable	5om2A-5h7wA: 8.70 5om2B-5h7wA: 4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5hdm	GLUTAMATE-1-SEMIALDE HYDE 2,1-AMINOMUTASE 1, CHLOROPLASTIC (Arabidopsis thaliana)	PF00202 (Aminotran_3)	5	VAL A 118 LEU A 272 PHE A 252 VAL A 112 ILE A 115	None	1.21A	5om2A-5hdmA: undetectable 5om2B-5hdmA: undetectable	5om2A-5hdmA: 11.08 5om2B-5hdmA: 10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ic7	PUTATIVE UNCHARACTERIZED PROTEIN (Chaetomium thermophilum)	no annotation	5	VAL A 545 LEU A 566 ALA A 565 VAL A 604 ILE A 593	None	0.94A	5om2A-5ic7A: undetectable 5om2B-5ic7A: undetectable	5om2A-5ic7A: 10.46 5om2B-5ic7A: 8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5iy9	DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 (Homo sapiens)	PF00575 (S1) PF03876 (SHS2_Rpb7-N)	5	VAL G  26 LEU G  22 PHE G  18 VAL G  66 HIS G  14	None	1.17A	5om2A-5iy9G: undetectable 5om2B-5iy9G: undetectable	5om2A-5iy9G: 18.75 5om2B-5iy9G: 17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ket	ALDO-KETO REDUCTASE 1 (Coptotermes gestroi)	PF00248 (Aldo_ket_red)	5	LEU A  62 PHE A  66 ASP A  67 VAL A  76 ILE A  78	None	1.18A	5om2A-5ketA: undetectable 5om2B-5ketA: undetectable	5om2A-5ketA: 14.41 5om2B-5ketA: 7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5l9w	ACETOPHENONE CARBOXYLASE ALPHA SUBUNIT (Aromatoleum aromaticum)	PF01968 (Hydantoinase_A) PF05378 (Hydant_A_N)	5	LEU b  59 ALA b  60 PHE b  58 VAL b   4 ILE b  65	None	0.97A	5om2A-5l9wb: undetectable 5om2B-5l9wb: undetectable	5om2A-5l9wb: 8.28 5om2B-5l9wb: 8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ngk	GLUCOSYLCERAMIDASE (Bacteroides thetaiotaomicron)	PF02055 (Glyco_hydro_30) PF17189 (Glyco_hydro_30C)	5	LEU A 263 ALA A 213 PHE A 216 VAL A 233 ILE A 276	None	1.20A	5om2A-5ngkA: undetectable 5om2B-5ngkA: undetectable	5om2A-5ngkA: 10.42 5om2B-5ngkA: 5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5uxx	RNA POLYMERASE SIGMA FACTOR (Bartonella quintana)	no annotation	5	LEU A 110 ALA A 109 PHE A 106 ASP A 105 ILE A 121	None	0.94A	5om2A-5uxxA: undetectable 5om2B-5uxxA: undetectable	5om2A-5uxxA: 22.89 5om2B-5uxxA: 15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5w7z	DNA POLYMERASE III SUBUNIT BETA (Rickettsia conorii)	PF00712 (DNA_pol3_beta) PF02767 (DNA_pol3_beta_2) PF02768 (DNA_pol3_beta_3)	5	VAL A 340 LEU A 337 PHE A 332 VAL A 360 ILE A 362	None	1.07A	5om2A-5w7zA: undetectable 5om2B-5w7zA: undetectable	5om2A-5w7zA: 13.68 5om2B-5w7zA: 8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5x2g	CRISPR-ASSOCIATED ENDONUCLEASE CAS9 (Campylobacter jejuni)	no annotation	5	LEU A 938 PHE A 939 VAL A 907 HIS A 924 ILE A 896	None	1.17A	5om2A-5x2gA: undetectable 5om2B-5x2gA: undetectable	5om2A-5x2gA: 6.85 5om2B-5x2gA: 4.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5xex	POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERA SE (Staphylococcus aureus)	no annotation	5	VAL A 246 ALA A 299 ASP A  55 VAL A 279 ILE A 278	None	1.11A	5om2A-5xexA: 0.1 5om2B-5xexA: undetectable	5om2A-5xexA: 9.12 5om2B-5xexA: 6.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6d46	BETA SLIDING CLAMP (Rickettsia typhi)	no annotation	5	VAL A 340 LEU A 337 PHE A 332 VAL A 362 ILE A 364	None	1.13A	5om2A-6d46A: undetectable 5om2B-6d46A: undetectable	5om2A-6d46A: 31.82 5om2B-6d46A: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6eon	BETA-GALACTOSIDASE (Bacteroides thetaiotaomicron)	no annotation	5	LEU A 163 ALA A  99 ASP A  97 VAL A 112 ILE A 174	None	1.11A	5om2A-6eonA: undetectable 5om2B-6eonA: undetectable	5om2A-6eonA: 6.60 5om2B-6eonA: 4.99