SIMILAR PATTERNS OF AMINO ACIDS FOR 5OH1_A_EF2A202
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz5 | ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF00982(Glyco_transf_20) | 4 | PRO A 158PHE A 88TRP A 85TYR A 265 | None | 1.43A | 5oh1A-1gz5A:undetectable | 5oh1A-1gz5A:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | PRO A 229PHE A 228TRP A 155TYR A 157 | None | 1.46A | 5oh1A-1ygpA:0.0 | 5oh1A-1ygpA:6.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eg9 | ADP-RIBOSYL CYCLASE1 (Mus musculus) |
PF02267(Rib_hydrolayse) | 4 | ASN A 187PRO A 188PHE A 97TRP A 53 | None | 1.34A | 5oh1A-2eg9A:undetectable | 5oh1A-2eg9A:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g8g | CAPSID (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PRO A 299PHE A 636TRP A 617TYR A 343 | None | 1.48A | 5oh1A-2g8gA:undetectable | 5oh1A-2g8gA:10.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w61 | GLYCOLIPID-ANCHOREDSURFACE PROTEIN 2 (Saccharomycescerevisiae) |
PF03198(Glyco_hydro_72)PF07983(X8) | 4 | ASN A 141PRO A 145PHE A 189TYR A 155 | None | 1.25A | 5oh1A-2w61A:0.0 | 5oh1A-2w61A:9.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiv | BETA-GLUCOSIDASE (Secale cereale) |
PF00232(Glyco_hydro_1) | 4 | ASN A 190PHE A 187TRP A 144TYR A 168 | None | 1.34A | 5oh1A-3aivA:0.0 | 5oh1A-3aivA:9.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4p | CAPSID PROTEIN VP1 (Adeno-associatedvirus) |
PF00740(Parvo_coat) | 4 | PRO A 310PHE A 639TRP A 620TYR A 354 | None | 1.48A | 5oh1A-3j4pA:0.0 | 5oh1A-3j4pA:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3juu | PORPHYRANASE B (Zobelliagalactanivorans) |
PF00722(Glyco_hydro_16) | 4 | ASN A 261PRO A 262TRP A 260TRP A 172 | None | 1.39A | 5oh1A-3juuA:0.0 | 5oh1A-3juuA:14.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kie | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PRO A 308PHE A 638TRP A 619TYR A 352 | None | 1.42A | 5oh1A-3kieA:0.0 | 5oh1A-3kieA:7.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lpp | SUCRASE-ISOMALTASE (Homo sapiens) |
PF00088(Trefoil)PF01055(Glyco_hydro_31)PF16863(NtCtMGAM_N) | 4 | ASN A 319PRO A 315PHE A 670TYR A 660 | None | 1.48A | 5oh1A-3lppA:undetectable | 5oh1A-3lppA:8.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ng9 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PRO A 309PHE A 638TRP A 619TYR A 353 | None | 1.43A | 5oh1A-3ng9A:undetectable | 5oh1A-3ng9A:8.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nix | FLAVOPROTEIN/DEHYDROGENASE (Cytophagahutchinsonii) |
PF01494(FAD_binding_3) | 4 | PRO A 50PHE A 89TRP A 99TRP A 101 | None | 1.20A | 5oh1A-3nixA:undetectable | 5oh1A-3nixA:10.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ntt | CAPSID PROTEIN (Adeno-associateddependoparvovirusB) |
PF00740(Parvo_coat) | 4 | PRO A 299PHE A 627TRP A 608TYR A 343 | None | 1.50A | 5oh1A-3nttA:undetectable | 5oh1A-3nttA:7.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogr | BETA-GALACTOSIDASE (Trichodermareesei) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | PRO A 69PHE A 70TRP A 350TYR A 948 | None | 1.40A | 5oh1A-3ogrA:undetectable | 5oh1A-3ogrA:6.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ra2 | CAPSID PROTEIN (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PRO A 311PHE A 640TRP A 621TYR A 355 | None | 1.38A | 5oh1A-3ra2A:undetectable | 5oh1A-3ra2A:10.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3shm | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PRO A 309PHE A 638TRP A 619TYR A 353 | None | 1.44A | 5oh1A-3shmA:undetectable | 5oh1A-3shmA:7.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ux1 | CAPSID PROTEIN VP1 (Adeno-associateddependoparvovirusA) |
PF00740(Parvo_coat) | 4 | PRO A 310PHE A 638TRP A 619TYR A 354 | None | 1.43A | 5oh1A-3ux1A:undetectable | 5oh1A-3ux1A:10.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w5n | PUTATIVERHAMNOSIDASE (Streptomycesavermitilis) |
PF05592(Bac_rhamnosid)PF08531(Bac_rhamnosid_N)PF17389(Bac_rhamnosid6H)PF17390(Bac_rhamnosid_C) | 4 | PRO A 628TRP A 347TRP A 380TYR A 350 | None | 1.31A | 5oh1A-3w5nA:undetectable | 5oh1A-3w5nA:6.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aee | ALPHA AMYLASE,CATALYTIC REGION (Staphylothermusmarinus) |
PF00128(Alpha-amylase) | 4 | ASN A 338PRO A 339PHE A 344TYR A 423 | None | 1.16A | 5oh1A-4aeeA:undetectable | 5oh1A-4aeeA:10.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aw7 | GH86ABETA-PORPHYRANASE (Bacteroidesplebeius) |
no annotation | 4 | ASN A 317PRO A 274PHE A 319TYR A 49 | NoneIOD A1704 ( 4.6A)NoneNone | 0.95A | 5oh1A-4aw7A:undetectable | 5oh1A-4aw7A:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci2 | PROTEIN CEREBLON (Gallus gallus) |
PF02190(LON_substr_bdg)PF03226(Yippee-Mis18) | 5 | ASN B 353PRO B 354TRP B 382TRP B 388TRP B 402 | LVY B1429 (-4.1A)LVY B1429 (-4.7A)LVY B1429 (-3.1A)LVY B1429 (-3.5A)LVY B1429 (-3.7A) | 0.46A | 5oh1A-4ci2B:16.0 | 5oh1A-4ci2B:12.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gkl | ALPHA-AMYLASE (Thermotoganeapolitana) |
PF00128(Alpha-amylase) | 4 | PRO A 284PHE A 278TRP A 353TYR A 351 | None | 1.46A | 5oh1A-4gklA:undetectable | 5oh1A-4gklA:12.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iov | CAPSID PROTEIN VP1 (Adeno-associatedvirus) |
PF00740(Parvo_coat) | 4 | PRO A 299PHE A 635TRP A 616TYR A 343 | None | 1.42A | 5oh1A-4iovA:undetectable | 5oh1A-4iovA:8.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iug | BETA-GALACTOSIDASE A (Aspergillusoryzae) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | PRO A 69PHE A 70TRP A 350TYR A 930 | None | 1.36A | 5oh1A-4iugA:undetectable | 5oh1A-4iugA:6.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l7a | UNCHARACTERIZEDPROTEIN (Bacteroidescaccae) |
PF15890(Peptidase_Mx1) | 4 | ASN A 59PRO A 60TRP A 52TYR A 297 | None | 1.29A | 5oh1A-4l7aA:undetectable | 5oh1A-4l7aA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rso | CAPSID PROTEIN VP1 (Non-humanprimateAdeno-associatedvirus) |
PF00740(Parvo_coat) | 4 | PRO A 310PHE A 638TRP A 619TYR A 354 | None | 1.46A | 5oh1A-4rsoA:undetectable | 5oh1A-4rsoA:8.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4v30 | CEREBLON ISOFORM 4 (Magnetospirillumgryphiswaldense) |
no annotation | 7 | ASN A 50PRO A 51PHE A 77TRP A 79TRP A 85TRP A 99TYR A 101 | LVY A 151 (-3.8A)LVY A 151 (-4.4A)LVY A 151 (-4.4A)LVY A 151 (-3.2A)LVY A 151 (-3.4A)LVY A 151 (-3.7A)LVY A 151 (-4.7A) | 0.16A | 5oh1A-4v30A:24.1 | 5oh1A-4v30A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ynu | GLUCOSE OXIDASE,PUTATIVE (Aspergillusflavus) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 4 | ASN A 318PHE A 414TRP A 415TYR A 337 | LGC A 602 ( 4.4A)NoneNoneNone | 1.41A | 5oh1A-4ynuA:undetectable | 5oh1A-4ynuA:7.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ckm | MANNAN-BINDINGLECTIN SERINEPEPTIDASE 2 (Rattusnorvegicus) |
PF00431(CUB)PF07645(EGF_CA) | 4 | PRO A 245PHE A 239TRP A 270TYR A 186 | None | 1.39A | 5oh1A-5ckmA:undetectable | 5oh1A-5ckmA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5huu | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE[UDP-FORMING] (Candidaalbicans) |
PF00982(Glyco_transf_20) | 4 | PRO A 175PHE A 101TRP A 98TYR A 283 | None | 1.39A | 5oh1A-5huuA:undetectable | 5oh1A-5huuA:9.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hvm | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Aspergillusfumigatus) |
PF00982(Glyco_transf_20) | 4 | PRO A 183PHE A 109TRP A 106TYR A 290 | None | 1.46A | 5oh1A-5hvmA:undetectable | 5oh1A-5hvmA:10.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxb | PROTEIN CEREBLON (Homo sapiens) |
no annotation | 5 | ASN Z 351PRO Z 352TRP Z 380TRP Z 386TRP Z 400 | 85C Z 502 (-3.6A)85C Z 502 (-4.4A)85C Z 502 (-3.2A)85C Z 502 (-3.4A)85C Z 502 (-3.7A) | 0.56A | 5oh1A-5hxbZ:11.4 | 5oh1A-5hxbZ:13.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ihr | PROBABLEBETA-GALACTOSIDASE A (Aspergillusniger) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | PRO A 69PHE A 70TRP A 350TYR A 932 | None | 1.40A | 5oh1A-5ihrA:undetectable | 5oh1A-5ihrA:6.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k50 | L-THREONINE3-DEHYDROGENASE (Trypanosomabrucei) |
no annotation | 4 | PRO A1281PHE A1123TRP A1280TYR A1144 | NoneNoneNoneGOL A1402 ( 4.3A) | 1.41A | 5oh1A-5k50A:undetectable | 5oh1A-5k50A:13.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5koh | NITROGENASE FEMOBETA SUBUNIT PROTEINNIFK (Gluconacetobacterdiazotrophicus) |
PF00148(Oxidored_nitro)PF11844(DUF3364) | 4 | ASN B 440PRO B 460PHE B 459TYR B 313 | None | 1.36A | 5oh1A-5kohB:undetectable | 5oh1A-5kohB:9.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mrt | LYTIC ENDOPEPTIDASEPREPROENZYME (Lysobacter sp.XL1) |
no annotation | 4 | ASN A 65PRO A 64PHE A 63TYR A 198 | NA A 305 (-3.4A)NoneNoneNone | 1.48A | 5oh1A-5mrtA:undetectable | 5oh1A-5mrtA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5swi | SUGAR HYDROLASE (Streptococcuspneumoniae) |
no annotation | 4 | ASN B 304PRO B 273PHE B 301TYR B 74 | None | 1.43A | 5oh1A-5swiB:undetectable | 5oh1A-5swiB:8.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tvg | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Burkholderiavietnamiensis) |
PF00982(Glyco_transf_20) | 4 | PRO A 160PHE A 90TRP A 87TYR A 268 | None | 1.43A | 5oh1A-5tvgA:undetectable | 5oh1A-5tvgA:10.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v0t | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Paraburkholderiaxenovorans) |
PF00982(Glyco_transf_20) | 4 | PRO A 168PHE A 98TRP A 95TYR A 280 | None | 1.43A | 5oh1A-5v0tA:undetectable | 5oh1A-5v0tA:10.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5znp | SHORT LIFE FAMILYPROTEIN (Populustrichocarpa) |
no annotation | 4 | ASN A 134PRO A 135PHE A 124TYR A 64 | None | 1.49A | 5oh1A-5znpA:undetectable | 5oh1A-5znpA:undetectable |