SIMILAR PATTERNS OF AMINO ACIDS FOR 5OG9_A_TESA504

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a3x PYRUVATE KINASE

(Saccharomyces
cerevisiae) 		PF00224
(PK)
PF02887
(PK_C) 		4 VAL A 318
ILE A  23
THR A 335
LEU A 301
 None
 0.78A 5og9A-1a3xA:
0.0		 5og9A-1a3xA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dk8 AXIN

(Homo sapiens) 		PF00615
(RGS) 		4 ILE A 214
GLU A 225
THR A 197
THR A 201
 None
 0.72A 5og9A-1dk8A:
undetectable		 5og9A-1dk8A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f59 IMPORTIN BETA-1

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 ILE A 363
ALA A 389
LEU A 326
THR A 327
 None
 0.79A 5og9A-1f59A:
0.0		 5og9A-1f59A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1foh PHENOL HYDROXYLASE

(Cutaneotrichosporon
cutaneum) 		PF01494
(FAD_binding_3)
PF07976
(Phe_hydrox_dim) 		4 VAL A 138
THR A 377
ALA A  18
LEU A  20
 None
None
FAD  A 801 (-3.3A)
None
 0.77A 5og9A-1fohA:
0.9		 5og9A-1fohA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ha5 STREPTOCOCCAL
PYOGENIC EXOTOXIN A1

(Streptococcus
pyogenes) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 ILE A1123
VAL A1216
LEU A1153
THR A1154
 None
 0.73A 5og9A-1ha5A:
undetectable		 5og9A-1ha5A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lgf P450 MONOOXYGENASE

(Amycolatopsis
orientalis) 		PF00067
(p450) 		4 ILE A 309
VAL A  51
LEU A 312
THR A 281
 None
 0.78A 5og9A-1lgfA:
31.9		 5og9A-1lgfA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mec MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP1)

(Cardiovirus A) 		no annotation 4 ILE 1 234
VAL 1  48
ALA 1 176
LEU 1 141
 None
 0.48A 5og9A-1mec1:
undetectable		 5og9A-1mec1:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oru YUAD PROTEIN

(Bacillus
subtilis) 		no annotation 4 ILE A 176
ILE A  66
THR A  22
LEU A  12
 None
 0.68A 5og9A-1oruA:
undetectable		 5og9A-1oruA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvj PYROGENIC EXOTOXIN B

(Streptococcus
pyogenes) 		PF01640
(Peptidase_C10)
PF13734
(Inhibitor_I69) 		4 ILE A 261
THR A 190
LEU A 169
THR A 170
 None
 0.77A 5og9A-1pvjA:
0.0		 5og9A-1pvjA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qup SUPEROXIDE DISMUTASE
1 COPPER CHAPERONE

(Saccharomyces
cerevisiae) 		PF00080
(Sod_Cu)
PF00403
(HMA) 		4 ILE A 133
THR A 114
ALA A 178
LEU A 176
 None
 0.76A 5og9A-1qupA:
0.0		 5og9A-1qupA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1n 4-ALPHA-GLUCANOTRANS
FERASE

(Solanum
tuberosum) 		PF02446
(Glyco_hydro_77) 		5 ILE A 447
VAL A 440
ALA A 460
LEU A 456
THR A 417
 None
 1.48A 5og9A-1x1nA:
1.4		 5og9A-1x1nA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xxg ENTEROTOXIN

(Staphylococcus
aureus) 		PF01123
(Stap_Strp_toxin)
PF02876
(Stap_Strp_tox_C) 		4 ILE A 132
VAL A 228
LEU A 162
THR A 163
 None
 0.60A 5og9A-1xxgA:
undetectable		 5og9A-1xxgA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5a C.BCLI

([Bacillus]
caldolyticus) 		PF01381
(HTH_3) 		4 ILE A  40
VAL A  24
ALA A  60
LEU A  62
 None
 0.79A 5og9A-2b5aA:
undetectable		 5og9A-2b5aA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ddz 190AA LONG
HYPOTHETICAL PROTEIN

(Pyrococcus
horikoshii) 		PF04017
(DUF366) 		4 ILE A 136
VAL A  69
ILE A   8
GLU A 163
 None
 0.76A 5og9A-2ddzA:
undetectable		 5og9A-2ddzA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw4 LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 ILE A 780
ILE A 825
ALA A 799
THR A 624
 None
None
None
FAD  A1001 (-4.9A)
 0.72A 5og9A-2dw4A:
3.1		 5og9A-2dw4A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1l 16S RRNA PROCESSING
PROTEIN

(Pseudomonas
aeruginosa) 		PF01782
(RimM)
PF05239
(PRC) 		4 ILE A  11
ILE A  14
ALA A  53
LEU A  55
 None
None
GOL  A 178 ( 3.8A)
None
 0.66A 5og9A-2f1lA:
undetectable		 5og9A-2f1lA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ii1 ACETAMIDASE

(Bacillus
halodurans) 		PF03069
(FmdA_AmdA) 		4 VAL A  29
ILE A  76
ALA A 175
LEU A  63
 None
 0.77A 5og9A-2ii1A:
undetectable		 5og9A-2ii1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ii1 ACETAMIDASE

(Bacillus
halodurans) 		PF03069
(FmdA_AmdA) 		4 VAL A  29
THR A 136
ALA A 175
LEU A  63
 None
 0.76A 5og9A-2ii1A:
undetectable		 5og9A-2ii1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j9i GLUTAMATE-AMMONIA
LIGASE
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		PF00120
(Gln-synt_C) 		4 ILE A 318
GLU A 365
ALA A 266
LEU A 264
 None
 0.77A 5og9A-2j9iA:
undetectable		 5og9A-2j9iA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mul E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		PF14377
(DUF4414) 		4 VAL A2984
THR A2951
ALA A2975
LEU A2973
 None
 0.74A 5og9A-2mulA:
undetectable		 5og9A-2mulA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nv4 UPF0066 PROTEIN
AF_0241

(Archaeoglobus
fulgidus) 		PF01980
(UPF0066) 		4 ILE A   6
ILE A  51
GLU A  46
LEU A  42
 None
 0.78A 5og9A-2nv4A:
undetectable		 5og9A-2nv4A:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4b RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 ILE A 944
VAL A 949
ILE A 910
LEU A 821
 None
 0.71A 5og9A-2r4bA:
undetectable		 5og9A-2r4bA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rg2 CHOLOYLGLYCINE
HYDROLASE

(Clostridium
perfringens) 		PF02275
(CBAH) 		4 ILE A 230
VAL A 172
ILE A 255
ALA A 238
 None
 0.72A 5og9A-2rg2A:
undetectable		 5og9A-2rg2A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbn TERMINASE LARGE
SUBUNIT

(Bacillus phage
SPP1) 		PF17288
(Terminase_3C) 		4 ILE A 373
ILE A 249
ALA A 362
LEU A 243
 None
 0.77A 5og9A-2wbnA:
undetectable		 5og9A-2wbnA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wbp L-ARGININE
BETA-HYDROXYLASE

(Streptomyces
vinaceus) 		PF02668
(TauD) 		4 ILE A 309
VAL A  88
ALA A 193
LEU A 301
 None
 0.65A 5og9A-2wbpA:
undetectable		 5og9A-2wbpA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12) 		4 ILE A 534
VAL A 556
ALA A 521
THR A 616
 None
None
None
U  D   6 ( 2.8A)
 0.77A 5og9A-2xzoA:
undetectable		 5og9A-2xzoA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zoo PROBABLE NITRITE
REDUCTASE

(Pseudoalteromonas
haloplanktis) 		PF00034
(Cytochrom_C)
PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3) 		4 VAL A 214
THR A 200
ALA A 291
LEU A 293
 None
 0.72A 5og9A-2zooA:
undetectable		 5og9A-2zooA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6v KINESIN-LIKE PROTEIN
KIF3C

(Homo sapiens) 		PF00225
(Kinesin) 		4 ILE A 148
VAL A 245
ILE A 221
LEU A 326
 None
 0.62A 5og9A-3b6vA:
undetectable		 5og9A-3b6vA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3daf 5,10-METHENYLTETRAHY
DROMETHANOPTERIN
HYDROGENASE

(Methanocaldococcus
jannaschii) 		PF03201
(HMD) 		5 ILE A  96
THR A  45
ALA A  25
LEU A  39
THR A  40
 None
 1.47A 5og9A-3dafA:
undetectable		 5og9A-3dafA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dj4 BIFUNCTIONAL PROTEIN
GLMU

(Mycobacterium
tuberculosis) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		4 VAL A 412
ILE A 389
ALA A 381
THR A 406
 None
 0.65A 5og9A-3dj4A:
undetectable		 5og9A-3dj4A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fww BIFUNCTIONAL PROTEIN
GLMU

(Yersinia pestis) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		4 VAL A 401
ILE A 378
ALA A 370
THR A 395
 None
 0.72A 5og9A-3fwwA:
undetectable		 5og9A-3fwwA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gaa UNCHARACTERIZED
PROTEIN TA1441

(Thermoplasma
acidophilum) 		PF09754
(PAC2) 		4 ILE A 124
ILE A  98
LEU A 110
THR A 109
 None
 0.68A 5og9A-3gaaA:
undetectable		 5og9A-3gaaA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnl UNCHARACTERIZED
PROTEIN, DUF633,
LMOF2365_1472

(Listeria
monocytogenes) 		PF04816
(TrmK) 		4 ILE A  95
ILE A 126
ALA A  43
THR A  48
 None
 0.77A 5og9A-3gnlA:
4.5		 5og9A-3gnlA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hv0 TRYPTOPHANYL-TRNA
SYNTHETASE

(Cryptosporidium
parvum) 		PF00579
(tRNA-synt_1b) 		4 VAL A 290
ILE A 485
GLU A 554
LEU A 558
 None
 0.73A 5og9A-3hv0A:
undetectable		 5og9A-3hv0A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibr BACTERIOPHYTOCHROME

(Pseudomonas
aeruginosa) 		PF00360
(PHY)
PF01590
(GAF)
PF08446
(PAS_2) 		4 VAL A  68
ILE A  90
ALA A  28
LEU A 108
 None
 0.78A 5og9A-3ibrA:
undetectable		 5og9A-3ibrA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1j ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF05362
(Lon_C)
PF13654
(AAA_32) 		4 VAL A 357
ILE A  33
GLU A  26
LEU A  23
 None
 0.75A 5og9A-3k1jA:
undetectable		 5og9A-3k1jA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k50 PUTATIVE S41
PROTEASE

(Bacteroides
fragilis) 		PF03572
(Peptidase_S41) 		4 VAL A 250
ILE A 343
THR A 423
LEU A 416
 None
 0.58A 5og9A-3k50A:
undetectable		 5og9A-3k50A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lpe PUTATIVE
TRANSCRIPTION
ANTITERMINATION
PROTEIN NUSG

(Methanocaldococcus
jannaschii) 		PF03439
(Spt5-NGN) 		4 ILE A  15
VAL A  45
ILE A  66
LEU A  56
 None
 0.75A 5og9A-3lpeA:
undetectable		 5og9A-3lpeA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n5m ADENOSYLMETHIONINE-8
-AMINO-7-OXONONANOAT
E AMINOTRANSFERASE

(Bacillus
anthracis) 		PF00202
(Aminotran_3) 		4 ILE A 213
ILE A 250
GLU A 118
ALA A 156
 None
 0.71A 5og9A-3n5mA:
undetectable		 5og9A-3n5mA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o1l FORMYLTETRAHYDROFOLA
TE DEFORMYLASE

(Pseudomonas
syringae group
genomosp. 3) 		PF00551
(Formyl_trans_N) 		4 VAL A  89
ILE A 188
ALA A 266
LEU A 268
 None
 0.77A 5og9A-3o1lA:
undetectable		 5og9A-3o1lA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oc7 ENOYL-COA HYDRATASE

(Mycobacterium
avium) 		PF00378
(ECH_1) 		4 ILE A 111
GLU A 141
THR A 140
ALA A 138
 None
 0.73A 5og9A-3oc7A:
undetectable		 5og9A-3oc7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oq3 IFN-ALPHA/BETA
BINDING PROTEIN C12R
INTERFERON ALPHA-5

(Ectromelia
virus;
Mus musculus) 		PF00047
(ig)
PF00143
(Interferon)
PF13895
(Ig_2) 		4 ILE B 272
VAL A 156
LEU A  15
THR A  16
 None
 0.75A 5og9A-3oq3B:
undetectable		 5og9A-3oq3B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr2 TRYPTOPHAN SYNTHASE
BETA CHAIN

(Salmonella
enterica) 		PF00291
(PALP) 		4 ILE B 345
GLU B  78
ALA B  58
THR B  57
 None
 0.69A 5og9A-3pr2B:
undetectable		 5og9A-3pr2B:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q2b COFILIN/ACTIN-DEPOLY
MERIZING FACTOR
HOMOLOG 1

(Plasmodium
falciparum) 		PF00241
(Cofilin_ADF) 		4 ILE A  60
VAL A  65
ILE A 112
LEU A  50
 None
 0.74A 5og9A-3q2bA:
undetectable		 5og9A-3q2bA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q8n 4-AMINOBUTYRATE
TRANSAMINASE

(Mycolicibacterium
smegmatis) 		PF00202
(Aminotran_3) 		4 ILE A  67
VAL A 411
ALA A 443
LEU A 441
 None
 0.63A 5og9A-3q8nA:
undetectable		 5og9A-3q8nA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q9t CHOLINE
DEHYDROGENASE AND
RELATED
FLAVOPROTEINS

(Aspergillus
oryzae) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ILE A  12
VAL A 216
LEU A  91
THR A  90
 None
 0.77A 5og9A-3q9tA:
undetectable		 5og9A-3q9tA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sb4 HYPOTHETICAL LEUCINE
RICH REPEAT PROTEIN

(Bacteroides
thetaiotaomicron) 		PF13306
(LRR_5) 		4 ILE A  81
THR A  90
ALA A 108
LEU A  64
 None
 0.78A 5og9A-3sb4A:
undetectable		 5og9A-3sb4A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3twd BIFUNCTIONAL PROTEIN
GLMU

(Escherichia
coli) 		PF00132
(Hexapep) 		4 VAL A 401
ILE A 378
ALA A 370
THR A 395
 None
 0.76A 5og9A-3twdA:
undetectable		 5og9A-3twdA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uaq LBPB B-LOBE

(Moraxella bovis) 		PF01298
(TbpB_B_D)
PF17484
(TbpB_A) 		4 ILE A 277
THR A 163
ALA A 318
LEU A 321
 None
 0.74A 5og9A-3uaqA:
undetectable		 5og9A-3uaqA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wz0 RIBONUCLEASE P
PROTEIN COMPONENT 2

(Thermococcus
kodakarensis) 		no annotation 4 ILE C  34
VAL C  70
LEU C  84
THR C  85
 None
 0.75A 5og9A-3wz0C:
undetectable		 5og9A-3wz0C:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP

(Salmonella
enterica) 		PF00814
(Peptidase_M22) 		4 ILE B 305
VAL B   3
ALA B 319
THR B 318
 None
 0.78A 5og9A-3zeuB:
undetectable		 5og9A-3zeuB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cpd ALCOHOL
DEHYDROGENASE

(Thermus sp.
ATN1) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ILE A 290
VAL A 263
ILE A 175
LEU A 254
 None
 0.74A 5og9A-4cpdA:
undetectable		 5og9A-4cpdA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4u MANDALATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(unidentified) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 253
GLU A 233
THR A 208
LEU A 205
 None
 0.73A 5og9A-4e4uA:
undetectable		 5og9A-4e4uA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5t MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Labrenzia
alexandrii) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ILE A 259
GLU A 239
THR A 214
LEU A 211
 None
MG  A 501 (-3.0A)
None
None
 0.66A 5og9A-4e5tA:
undetectable		 5og9A-4e5tA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1h SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		4 ILE A 112
THR A 217
ALA A 155
LEU A 153
 None
 0.69A 5og9A-4g1hA:
undetectable		 5og9A-4g1hA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1j SORTASE FAMILY
PROTEIN

(Streptococcus
agalactiae) 		PF04203
(Sortase) 		4 ILE A 119
THR A 224
ALA A 162
LEU A 160
 None
 0.66A 5og9A-4g1jA:
undetectable		 5og9A-4g1jA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdl AUTOPHAGY PROTEIN 5

(Homo sapiens) 		PF04106
(APG5) 		4 ILE B 189
ILE B 227
LEU B 215
THR B 214
 None
 0.67A 5og9A-4gdlB:
undetectable		 5og9A-4gdlB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gdl AUTOPHAGY PROTEIN 5

(Homo sapiens) 		PF04106
(APG5) 		4 VAL B 238
ILE B 227
LEU B 215
THR B 214
 None
 0.49A 5og9A-4gdlB:
undetectable		 5og9A-4gdlB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gky PROTEIN ERGIC-53

(Homo sapiens) 		PF03388
(Lectin_leg-like) 		4 ILE A 125
VAL A 147
ALA A 231
LEU A 212
 None
 0.74A 5og9A-4gkyA:
undetectable		 5og9A-4gkyA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW) 		4 ILE A 786
ILE A 819
ALA A 793
THR A 626
 None
 0.68A 5og9A-4hsuA:
undetectable		 5og9A-4hsuA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4inf METAL-DEPENDENT
HYDROLASE

(Novosphingobium
aromaticivorans) 		PF04909
(Amidohydro_2) 		4 ILE A 276
VAL A 284
LEU A 220
THR A 216
 None
 0.74A 5og9A-4infA:
undetectable		 5og9A-4infA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0q ELONGATION FACTOR
TU-A

(Pseudomonas
putida) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		4 ILE A 218
THR A 285
LEU A 246
THR A 257
 None
 0.72A 5og9A-4j0qA:
undetectable		 5og9A-4j0qA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j5u SERINE
HYDROXYMETHYLTRANSFE
RASE

(Rickettsia
rickettsii) 		PF00464
(SHMT) 		5 ILE A  30
VAL A 385
THR A 313
ALA A 294
LEU A 363
 None
 1.36A 5og9A-4j5uA:
undetectable		 5og9A-4j5uA:
25.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ldq METHYLTHIORIBOSE-1-P
HOSPHATE ISOMERASE

(Homo sapiens) 		PF01008
(IF-2B) 		4 VAL A 250
THR A 170
ALA A 181
THR A 180
 None
 0.77A 5og9A-4ldqA:
1.5		 5og9A-4ldqA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ll8 MYOSIN-4

(Saccharomyces
cerevisiae) 		PF01843
(DIL) 		5 ILE A1163
VAL A1151
GLU A1208
ALA A1201
LEU A1223
 None
 1.09A 5og9A-4ll8A:
1.8		 5og9A-4ll8A:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1q L-LACTATE
DEHYDROGENASE

([Bacillus]
selenitireducens) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 VAL A   8
ILE A 118
ALA A 246
LEU A 248
 None
 0.73A 5og9A-4m1qA:
undetectable		 5og9A-4m1qA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nwz FAD-DEPENDENT
PYRIDINE
NUCLEOTIDE-DISULFIDE
OXIDOREDUCTASE

(Caldalkalibacillus
thermarum) 		PF07992
(Pyr_redox_2) 		4 ILE A  65
ILE A  33
ALA A  18
LEU A  20
 None
 0.78A 5og9A-4nwzA:
undetectable		 5og9A-4nwzA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p0f SERINE PROTEASE
INHIBITOR 4, ISOFORM
B

(Drosophila
melanogaster) 		PF00079
(Serpin) 		4 ILE A 316
VAL A 165
ALA A 131
THR A 134
 None
 0.77A 5og9A-4p0fA:
undetectable		 5og9A-4p0fA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfv ANK-N5C-281

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4) 		4 ILE A  97
VAL A  87
GLU A 118
LEU A 122
 None
 0.77A 5og9A-4qfvA:
undetectable		 5og9A-4qfvA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfv ANK-N5C-281

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4) 		4 ILE A 130
VAL A 120
GLU A 151
LEU A 155
 None
 0.75A 5og9A-4qfvA:
undetectable		 5og9A-4qfvA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y2w ALANINE RACEMASE 1

(Caldanaerobacter
subterraneus) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 ILE A 227
GLU A 361
ALA A 352
THR A 357
 PO4  A 401 (-4.4A)
None
None
None
 0.78A 5og9A-4y2wA:
undetectable		 5og9A-4y2wA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zn1 TRANSCRIPTION
ELONGATION FACTOR
SPT5

(Methanocaldococcus
jannaschii) 		PF00467
(KOW)
PF03439
(Spt5-NGN) 		4 ILE A  15
VAL A  45
ILE A  66
LEU A  56
 None
 0.78A 5og9A-4zn1A:
undetectable		 5og9A-4zn1A:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpx ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF13654
(AAA_32) 		4 VAL A 357
ILE A  33
GLU A  26
LEU A  23
 None
 0.62A 5og9A-4zpxA:
undetectable		 5og9A-4zpxA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7t TRNA
(ADENINE(9)-N1)-METH
YLTRANSFERASE

(Sulfolobus
acidocaldarius) 		no annotation 4 VAL A  91
ILE A 157
ALA A 197
LEU A 147
 None
None
None
PEG  A1248 (-4.9A)
 0.76A 5og9A-5a7tA:
undetectable		 5og9A-5a7tA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbo TRANSLATION
INITIATION FACTOR
EIF-2B-LIKE PROTEIN

(Chaetomium
thermophilum) 		PF01008
(IF-2B) 		5 ILE A 286
VAL A 295
THR A 429
ALA A 378
THR A 374
 None
 1.17A 5og9A-5dboA:
2.2		 5og9A-5dboA:
22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e78 BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE

(Bacillus
megaterium) 		PF00067
(p450) 		5 GLU A 267
THR A 268
ALA A 328
LEU A 437
THR A 438
 None
HEM  A 501 (-3.4A)
HEM  A 501 ( 3.8A)
None
None
 0.71A 5og9A-5e78A:
57.6		 5og9A-5e78A:
98.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5e78 BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE

(Bacillus
megaterium) 		PF00067
(p450) 		5 VAL A  78
THR A 268
ALA A 328
LEU A 437
THR A 438
 None
HEM  A 501 (-3.4A)
HEM  A 501 ( 3.8A)
None
None
 0.44A 5og9A-5e78A:
57.6		 5og9A-5e78A:
98.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f42 ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE

(Francisella
tularensis) 		PF00132
(Hexapep)
PF13720
(Acetyltransf_11) 		4 VAL A  42
ILE A  26
ALA A  18
THR A  36
 None
 0.75A 5og9A-5f42A:
undetectable		 5og9A-5f42A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gk2 KETOSYNTHASE STLD

(Photorhabdus
laumondii) 		PF08541
(ACP_syn_III_C) 		4 ILE A 220
ILE A 215
ALA A 136
LEU A 138
 None
 0.74A 5og9A-5gk2A:
undetectable		 5og9A-5gk2A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihs ENDOGLUCANASE,
GLYCOSIDE HYDROLASE
FAMILY 5 PROTEIN

(Cytophaga
hutchinsonii) 		PF00150
(Cellulase) 		4 ILE A 117
ILE A 152
GLU A 155
ALA A  85
 None
 0.76A 5og9A-5ihsA:
undetectable		 5og9A-5ihsA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jb3 30S RIBOSOMAL
PROTEIN S27E

(Pyrococcus
abyssi) 		PF01667
(Ribosomal_S27e) 		4 VAL W  27
ILE W  58
GLU W  46
ALA W  42
 None
 0.79A 5og9A-5jb3W:
undetectable		 5og9A-5jb3W:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kdm MAJOR TEGUMENT
PROTEIN

(Human
gammaherpesvirus
4) 		PF12818
(Tegument_dsDNA) 		5 ILE D 510
VAL D 541
ALA D 527
LEU D 525
THR D 523
 None
 1.18A 5og9A-5kdmD:
undetectable		 5og9A-5kdmD:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ket ALDO-KETO REDUCTASE
1

(Coptotermes
gestroi) 		PF00248
(Aldo_ket_red) 		4 ILE A 217
VAL A 193
GLU A 298
ALA A 251
 NAP  A 400 (-3.9A)
None
None
None
 0.64A 5og9A-5ketA:
undetectable		 5og9A-5ketA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kzm TRYPTOPHAN SYNTHASE
BETA CHAIN

(Francisella
tularensis) 		PF00291
(PALP) 		4 ILE B 344
GLU B  77
ALA B  57
THR B  56
 None
 0.69A 5og9A-5kzmB:
undetectable		 5og9A-5kzmB:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3d LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1A

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 ILE A 780
ILE A 825
ALA A 799
THR A 624
 None
 0.71A 5og9A-5l3dA:
2.8		 5og9A-5l3dA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l7v GLYCOSIDE HYDROLASE

(Bacteroides
vulgatus) 		PF13320
(DUF4091) 		4 ILE A 529
ILE A 560
GLU A 511
ALA A 454
 None
 0.72A 5og9A-5l7vA:
undetectable		 5og9A-5l7vA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o46 IRISTATIN

(Ixodes ricinus) 		no annotation 4 ILE B  41
ALA B  60
LEU B  37
THR B  36
 None
 0.70A 5og9A-5o46B:
undetectable		 5og9A-5o46B:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tj2 SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,GASDERMIN-B
FUSION PROTEIN

(Escherichia
coli;
Homo sapiens) 		PF04598
(Gasdermin)
PF13416
(SBP_bac_8) 		4 VAL A1396
GLU A1348
ALA A 363
THR A 366
 None
 0.66A 5og9A-5tj2A:
undetectable		 5og9A-5tj2A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vmk BIFUNCTIONAL PROTEIN
GLMU

(Acinetobacter
baumannii) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3)
PF14602
(Hexapep_2) 		4 VAL A 398
ILE A 375
ALA A 367
THR A 392
 None
 0.77A 5og9A-5vmkA:
undetectable		 5og9A-5vmkA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqd BETA-GLUCOSIDE
PHOSPHORYLASE BGLX

(unidentified) 		no annotation 5 ILE A 149
THR A 190
ALA A 235
LEU A 238
THR A 237
 None
 0.89A 5og9A-5vqdA:
undetectable		 5og9A-5vqdA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vzt F-BOX ONLY PROTEIN
31

(Homo sapiens) 		no annotation 4 ILE B 194
VAL B 164
GLU B 114
LEU B 139
 None
 0.78A 5og9A-5vztB:
undetectable		 5og9A-5vztB:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfs PE FAMILY PROTEIN
PE8
PPE FAMILY PROTEIN
PPE15

(Mycobacterium
tuberculosis) 		PF00823
(PPE)
no annotation 		4 ILE A  21
ILE B  49
LEU B  76
THR B  77
 None
 0.74A 5og9A-5xfsA:
undetectable		 5og9A-5xfsA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zov -

(-) 		no annotation 5 ILE A  84
VAL A 398
THR A  96
ALA A  92
THR A  93
 None
 1.32A 5og9A-5zovA:
2.5		 5og9A-5zovA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aon DIHYDROLIPOYL
DEHYDROGENASE

(Bordetella
pertussis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ILE A  10
VAL A 317
ALA A 293
LEU A 296
 FAD  A 501 (-4.7A)
None
None
None
 0.69A 5og9A-6aonA:
undetectable		 5og9A-6aonA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bm7 INACTIVE
S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROZYME

(Trypanosoma
brucei) 		no annotation 4 VAL E 124
ILE E  96
ALA E 109
LEU E 114
 PGE  E 402 (-4.9A)
None
None
None
 0.78A 5og9A-6bm7E:
undetectable		 5og9A-6bm7E:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eot DIPEPTIDYL PEPTIDASE
8

(Homo sapiens) 		no annotation 4 ILE A 301
VAL A 359
ILE A 350
THR A 243
 None
 0.75A 5og9A-6eotA:
undetectable		 5og9A-6eotA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k POLYSULPHIDE
REDUCTASE NRFD

(Rhodothermus
marinus) 		no annotation 4 ILE C 117
VAL C 299
ILE C 448
THR C  37
 None
 0.79A 5og9A-6f0kC:
1.8		 5og9A-6f0kC:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 266
GLU A  31
ALA A  68
THR A  69
 None
None
None
ZN  A1501 (-3.2A)
 0.76A 5og9A-6f42A:
undetectable		 5og9A-6f42A:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fml INO80

(Chaetomium
thermophilum) 		no annotation 4 ILE G1153
ALA G1109
LEU G1134
THR G1135
 None
 0.77A 5og9A-6fmlG:
undetectable		 5og9A-6fmlG:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ftl RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Skeletonema
marinoi) 		no annotation 4 ILE A 124
VAL A 128
ILE A  46
ALA A  88
 None
 0.79A 5og9A-6ftlA:
undetectable		 5og9A-6ftlA:
10.81