SIMILAR PATTERNS OF AMINO ACIDS FOR 5ODQ_A_ACTA703

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a0h MEIZOTHROMBIN

(Bos taurus) 		PF00051
(Kringle)
PF09396
(Thrombin_light) 		4 ARG A 179
ARG A 181
ALA A 215
PRO A 213
 None
 1.30A 5odqA-1a0hA:
undetectable		 5odqA-1a0hA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eo9 PROTOCATECHUATE
3,4-DIOXYGENASE BETA
CHAIN


(Acinetobacter
sp. ADP1) 		PF00775
(Dioxygenase_C)
PF12391
(PCDO_beta_N) 		4 ARG B 473
ALA B 348
PRO B 349
PHE B 351
 None
 1.24A 5odqA-1eo9B:
undetectable		 5odqA-1eo9B:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fn9 OUTER-CAPSID PROTEIN
SIGMA 3

(Reovirus sp.) 		PF00979
(Reovirus_cap) 		4 ARG A 208
ALA A 191
PRO A 188
PHE A 285
 None
 1.31A 5odqA-1fn9A:
undetectable		 5odqA-1fn9A:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gw1 MANNAN
ENDO-1,4-BETA-MANNOS
IDASE

(Cellvibrio
japonicus) 		PF02156
(Glyco_hydro_26) 		4 ARG A 307
ALA A 309
PRO A 316
GLU A 353
 None
 1.03A 5odqA-1gw1A:
undetectable		 5odqA-1gw1A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1im8 YECO

(Haemophilus
influenzae) 		PF13649
(Methyltransf_25) 		4 ARG A 142
ARG A 118
ALA A 144
GLU A 140
 None
SAI  A 302 ( 4.5A)
None
None
 1.28A 5odqA-1im8A:
3.3		 5odqA-1im8A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jzu LIPOCALIN Q83

(Coturnix
coturnix) 		PF00061
(Lipocalin) 		4 ARG A 102
ALA A 100
PHE A  66
GLU A  79
 None
 1.17A 5odqA-1jzuA:
undetectable		 5odqA-1jzuA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m5s FORMYLMETHANOFURAN--
TETRAHYDROMETHANOPTE
RIN
FORMYLTRANSFERASE

(Methanosarcina
barkeri) 		PF01913
(FTR)
PF02741
(FTR_C) 		4 ALA A 135
PRO A  66
PHE A 105
GLU A 152
 None
 1.32A 5odqA-1m5sA:
undetectable		 5odqA-1m5sA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 179
ALA A 177
PRO A 471
PHE A 172
 None
 1.24A 5odqA-1m9qA:
undetectable		 5odqA-1m9qA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pqu ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Haemophilus
influenzae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ARG A 364
ARG A  20
ALA A 359
PRO A 361
 None
 1.24A 5odqA-1pquA:
2.0		 5odqA-1pquA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu4 ORNITHINE
DECARBOXYLASE

(Trypanosoma
brucei) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ARG A 242
ALA A 244
PRO A 239
GLU A 249
 None
 1.10A 5odqA-1qu4A:
2.3		 5odqA-1qu4A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		4 ARG A 189
ALA A 187
PRO A 481
PHE A 182
 None
 1.13A 5odqA-1qw5A:
undetectable		 5odqA-1qw5A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5l PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)

(Homo sapiens) 		PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N) 		4 ARG A  54
ARG A  57
ALA A  58
PRO A 188
 None
 1.22A 5odqA-1r5lA:
undetectable		 5odqA-1r5lA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 ARG E 404
ARG E 405
ALA E 403
PHE E 408
 None
 1.40A 5odqA-1skyE:
undetectable		 5odqA-1skyE:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wg5 HETEROGENEOUS
NUCLEAR
RIBONUCLEOPROTEIN H

(Homo sapiens) 		PF00076
(RRM_1) 		4 ARG A  97
ARG A  19
ALA A  60
PRO A  49
 None
 1.33A 5odqA-1wg5A:
undetectable		 5odqA-1wg5A:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wk9 VALYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1) 		4 ARG A 318
ARG A 319
ALA A 321
PRO A 217
 None
 1.26A 5odqA-1wk9A:
undetectable		 5odqA-1wk9A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xcf TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Escherichia
coli) 		PF00290
(Trp_syntA) 		4 ARG A 140
ARG A 171
ALA A 143
PHE A 152
 None
 1.04A 5odqA-1xcfA:
undetectable		 5odqA-1xcfA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y56 HYPOTHETICAL PROTEIN
PH1363

(Pyrococcus
horikoshii) 		PF07992
(Pyr_redox_2)
PF13510
(Fer2_4) 		4 ARG A 232
ARG A 233
ALA A 236
PHE A 305
 None
 1.34A 5odqA-1y56A:
21.1		 5odqA-1y56A:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cfb GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE

(Synechococcus
elongatus) 		PF00202
(Aminotran_3) 		4 ARG A 110
ARG A 113
ALA A 114
PRO A 277
 None
 1.24A 5odqA-2cfbA:
undetectable		 5odqA-2cfbA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 ARG A 341
PRO A 335
PHE A 367
GLU A 368
 None
 1.42A 5odqA-2cvtA:
undetectable		 5odqA-2cvtA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i2x METHYLTRANSFERASE 1
METHYLTRANSFERASE 1

(Methanosarcina
barkeri;
Methanosarcina
barkeri) 		PF12176
(MtaB)
PF02310
(B12-binding)
PF02607
(B12-binding_2) 		4 ARG B  15
ARG A 363
ALA A 367
PRO A 365
 None
 1.41A 5odqA-2i2xB:
6.2		 5odqA-2i2xB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2icp ANTITOXIN HIGA

(Escherichia
coli) 		PF01381
(HTH_3) 		4 ARG A  25
ARG A  29
ALA A  28
PRO A  35
 None
 1.17A 5odqA-2icpA:
undetectable		 5odqA-2icpA:
9.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuu DNA TRANSLOCASE FTSK

(Pseudomonas
aeruginosa) 		PF01580
(FtsK_SpoIIIE) 		4 ARG A 703
ALA A 707
PRO A 316
PHE A 485
 None
 1.17A 5odqA-2iuuA:
undetectable		 5odqA-2iuuA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paa PHOSPHOGLYCERATE
KINASE, TESTIS
SPECIFIC

(Mus musculus) 		PF00162
(PGK) 		4 ARG A 170
ALA A 171
PRO A 408
GLU A 400
 None
 1.39A 5odqA-2paaA:
2.5		 5odqA-2paaA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pz0 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Caldanaerobacter
subterraneus) 		PF03009
(GDPD) 		4 ARG A  34
ALA A  31
PRO A  25
PHE A  94
 None
 1.17A 5odqA-2pz0A:
undetectable		 5odqA-2pz0A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tbv TOMATO BUSHY STUNT
VIRUS

(Tomato bushy
stunt virus) 		PF00729
(Viral_coat) 		4 ALA A 149
PRO A 136
PHE A 142
GLU A 110
 None
 1.20A 5odqA-2tbvA:
undetectable		 5odqA-2tbvA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vro ALDEHYDE
DEHYDROGENASE

(Paraburkholderia
xenovorans) 		PF00171
(Aldedh) 		4 ARG A  68
ARG A  65
ALA A 208
PRO A 205
 None
 1.38A 5odqA-2vroA:
3.7		 5odqA-2vroA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgh RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE SUBUNIT

(Homo sapiens) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC) 		4 ARG A 341
PRO A 335
PHE A 367
GLU A 368
 None
 1.41A 5odqA-2wghA:
undetectable		 5odqA-2wghA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xmr PROTEIN NDRG2

(Homo sapiens) 		PF03096
(Ndr) 		4 ARG A  48
ARG A  83
ALA A  50
PRO A  49
 None
ACT  A1306 (-3.7A)
None
None
 1.22A 5odqA-2xmrA:
2.4		 5odqA-2xmrA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn1 ALPHA-GALACTOSIDASE

(Lactobacillus
acidophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 ARG A 333
ARG A 633
PHE A 638
GLU A 634
 None
 1.42A 5odqA-2xn1A:
undetectable		 5odqA-2xn1A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y2w ARABINOFURANOSIDASE

(Bifidobacterium
longum) 		PF06964
(Alpha-L-AF_C) 		4 ARG A  62
ARG A 403
ALA A 405
PHE A 280
 None
 1.23A 5odqA-2y2wA:
undetectable		 5odqA-2y2wA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yyt OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Geobacillus
kaustophilus) 		PF00215
(OMPdecase) 		4 ARG A 205
ALA A 204
PRO A 201
PHE A   7
 None
 1.24A 5odqA-2yytA:
undetectable		 5odqA-2yytA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zpb NITRILE HYDRATASE
SUBUNIT BETA

(Rhodococcus
erythropolis) 		PF02211
(NHase_beta) 		4 ALA B 166
PRO B 164
PHE B 204
GLU B 177
 None
 1.37A 5odqA-2zpbB:
undetectable		 5odqA-2zpbB:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zy2 L-ASPARTATE
4-CARBOXYLYASE

(Pseudomonas sp.
ATCC 19121) 		PF00155
(Aminotran_1_2) 		4 ARG A  48
ALA A  50
PRO A  47
PHE A 396
 None
 1.07A 5odqA-2zy2A:
undetectable		 5odqA-2zy2A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahy BETA-GLUCOSIDASE

(Trichoderma
reesei) 		PF00232
(Glyco_hydro_1) 		4 ARG A 183
ALA A 180
PRO A 181
GLU A 124
 None
 1.40A 5odqA-3ahyA:
1.7		 5odqA-3ahyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermotoga
maritima) 		PF01926
(MMR_HSR1) 		4 ARG A  29
ALA A  31
PRO A  34
PHE A  71
 None
 1.22A 5odqA-3cnnA:
undetectable		 5odqA-3cnnA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cyv UROPORPHYRINOGEN
DECARBOXYLASE

(Shigella
flexneri) 		PF01208
(URO-D) 		4 ARG A   8
ARG A  11
ALA A  12
PRO A  22
 None
 1.43A 5odqA-3cyvA:
2.1		 5odqA-3cyvA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e53 FATTY-ACID-COA
LIGASE FADD28

(Mycobacterium
tuberculosis) 		PF00501
(AMP-binding) 		4 ARG A   4
ALA A   8
PRO A   7
GLU A 161
 None
 1.21A 5odqA-3e53A:
2.2		 5odqA-3e53A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 195
ALA A 193
PRO A 487
PHE A 188
 None
 1.04A 5odqA-3e7gA:
undetectable		 5odqA-3e7gA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdb PUTATIVE
PLP-DEPENDENT
BETA-CYSTATHIONASE

(Corynebacterium
diphtheriae) 		PF00155
(Aminotran_1_2) 		4 ARG A  73
ALA A 192
PRO A 193
PHE A  69
 None
 1.35A 5odqA-3fdbA:
undetectable		 5odqA-3fdbA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fdd L-ASPARTATE-BETA-DEC
ARBOXYLASE

(Comamonas
testosteroni) 		PF00155
(Aminotran_1_2) 		4 ARG A  48
ALA A  50
PRO A  47
PHE A 396
 None
 1.07A 5odqA-3fddA:
2.5		 5odqA-3fddA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g2p PCZA361.24

(Amycolatopsis
orientalis) 		PF13649
(Methyltransf_25) 		4 ARG A  76
PRO A  80
PHE A  81
GLU A  69
 SAH  A 500 (-3.4A)
None
None
SAH  A 500 (-4.2A)
 1.40A 5odqA-3g2pA:
4.0		 5odqA-3g2pA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Schizosaccharomyces
pombe) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 ARG A 737
ALA A 735
PHE A 761
GLU A 740
 None
 1.24A 5odqA-3h0gA:
undetectable		 5odqA-3h0gA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h7l ENDOGLUCANASE

(Vibrio
parahaemolyticus) 		PF00759
(Glyco_hydro_9)
PF02927
(CelD_N) 		4 ARG A 544
ALA A 529
PHE A 522
GLU A 523
 None
 1.23A 5odqA-3h7lA:
undetectable		 5odqA-3h7lA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		4 ARG A 236
ALA A 240
PRO A 205
PHE A 206
 None
 1.39A 5odqA-3i04A:
4.4		 5odqA-3i04A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jtx AMINOTRANSFERASE

(Neisseria
meningitidis) 		PF00155
(Aminotran_1_2) 		4 ARG A 342
ALA A 341
PRO A 354
PHE A 357
 None
 1.39A 5odqA-3jtxA:
undetectable		 5odqA-3jtxA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2w BETAINE-ALDEHYDE
DEHYDROGENASE

(Pseudoalteromonas
atlantica) 		PF00171
(Aldedh) 		4 ARG A 165
ALA A 155
PHE A 158
GLU A 108
 None
 1.40A 5odqA-3k2wA:
2.3		 5odqA-3k2wA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln6 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB

(Streptococcus
agalactiae) 		PF01071
(GARS_A)
PF04262
(Glu_cys_ligase) 		4 ARG A  79
ALA A  71
PRO A  69
PHE A 444
 None
 1.36A 5odqA-3ln6A:
undetectable		 5odqA-3ln6A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lop SUBSTRATE BINDING
PERIPLASMIC PROTEIN

(Ralstonia
solanacearum) 		PF13458
(Peripla_BP_6) 		4 ARG A 343
ALA A 106
PRO A 131
PHE A 149
 None
 1.36A 5odqA-3lopA:
5.2		 5odqA-3lopA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1a PUTATIVE
DEHYDROGENASE

(Streptomyces
avermitilis) 		PF00106
(adh_short) 		4 ARG A 116
ALA A 115
PRO A 114
GLU A 108
 None
 1.33A 5odqA-3m1aA:
2.6		 5odqA-3m1aA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n4h PUTATIVE TAUTOMERASE

(Corynebacterium
glutamicum) 		PF14552
(Tautomerase_2) 		4 ARG A  70
ALA A  34
PRO A  35
GLU A 114
 None
PR7  A   1 ( 3.5A)
None
PR7  A   1 ( 3.3A)
 1.20A 5odqA-3n4hA:
undetectable		 5odqA-3n4hA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr2 TRYPTOPHAN SYNTHASE
ALPHA CHAIN

(Salmonella
enterica) 		PF00290
(Trp_syntA) 		4 ARG A 140
ARG A 171
ALA A 143
PHE A 152
 None
 1.17A 5odqA-3pr2A:
2.5		 5odqA-3pr2A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pzr ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Vibrio cholerae) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ARG A 361
ARG A  19
ALA A 356
PRO A 358
 None
 1.24A 5odqA-3pzrA:
undetectable		 5odqA-3pzrA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qp6 CVIR TRANSCRIPTIONAL
REGULATOR

(Chromobacterium
violaceum) 		PF00196
(GerE)
PF03472
(Autoind_bind) 		4 ARG A 117
ALA A 118
PRO A  98
GLU A 112
 None
 1.41A 5odqA-3qp6A:
undetectable		 5odqA-3qp6A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rv6 ISOCHORISMATE
SYNTHASE/ISOCHORISMA
TE-PYRUVATE LYASE
MBTI

(Mycobacterium
tuberculosis) 		PF00425
(Chorismate_bind) 		4 ARG A 188
ARG A 189
ALA A 192
PRO A 428
 None
 1.12A 5odqA-3rv6A:
undetectable		 5odqA-3rv6A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sgh SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF12741
(SusD-like) 		4 ARG A 289
ARG A 288
ALA A 291
PRO A 290
 None
 0.87A 5odqA-3sghA:
undetectable		 5odqA-3sghA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txv PROBABLE TAGATOSE
6-PHOSPHATE KINASE

(Sinorhizobium
meliloti) 		PF08013
(Tagatose_6_P_K) 		4 ARG A 151
ARG A 154
ALA A 113
PRO A  98
 None
 1.28A 5odqA-3txvA:
undetectable		 5odqA-3txvA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3umv DEOXYRIBODIPYRIMIDIN
E PHOTO-LYASE

(Oryza sativa) 		PF00875
(DNA_photolyase) 		4 ARG A 155
ARG A 156
ALA A 158
PRO A 159
 None
 1.19A 5odqA-3umvA:
undetectable		 5odqA-3umvA:
23.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uw3 ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Burkholderia
thailandensis) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ARG A 365
ARG A  19
ALA A 360
PRO A 362
 EDO  A 374 (-3.9A)
EDO  A 374 ( 4.9A)
None
None
 1.22A 5odqA-3uw3A:
2.6		 5odqA-3uw3A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uxf FIMBRIAL SUBUNIT
TYPE 1

(Actinomyces
oris) 		no annotation 4 ARG A 222
ARG A 283
ALA A 286
GLU A 281
 None
 1.33A 5odqA-3uxfA:
undetectable		 5odqA-3uxfA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr1 PEPTIDE CHAIN
RELEASE FACTOR 3

(Desulfovibrio
vulgaris) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF16658
(RF3_C) 		4 ARG A 526
ALA A 393
PRO A 394
PHE A 427
 None
 1.42A 5odqA-3vr1A:
undetectable		 5odqA-3vr1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vse PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF10672
(Methyltrans_SAM) 		4 ALA A 171
PRO A 172
PHE A 174
GLU A 190
 None
 1.32A 5odqA-3vseA:
3.3		 5odqA-3vseA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wx5 CELLULASE

(uncultured
bacterium) 		PF01670
(Glyco_hydro_12) 		4 ARG A 201
ALA A 199
PRO A 171
GLU A 241
 None
 1.42A 5odqA-3wx5A:
undetectable		 5odqA-3wx5A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4am9 CHAPERONE SYCD

(Yersinia
enterocolitica) 		PF07720
(TPR_3) 		4 ARG A 105
ALA A 130
PRO A 104
PHE A 140
 None
 1.18A 5odqA-4am9A:
undetectable		 5odqA-4am9A:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hzu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA 1

(Lactobacillus
brevis) 		PF00005
(ABC_tran) 		4 ARG B 152
ARG B 153
ALA B 155
PRO B  94
 None
 1.34A 5odqA-4hzuB:
undetectable		 5odqA-4hzuB:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jhz BETA-GLUCURONIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 ARG A  87
ALA A  90
PRO A 113
GLU A 336
 None
 1.25A 5odqA-4jhzA:
undetectable		 5odqA-4jhzA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k9z PUTATIVE
THIOL-DISULFIDE
OXIDOREDUCTASE

(Bacteroides
vulgatus) 		PF08534
(Redoxin) 		4 ARG A 144
ALA A  68
PRO A 145
PHE A 128
 None
 1.40A 5odqA-4k9zA:
undetectable		 5odqA-4k9zA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgn CELLULOSE-BINDING,
FAMILY II

(Acidothermus
cellulolyticus) 		no annotation 4 ARG A 504
ALA A 507
PRO A 471
PHE A 495
 None
 1.34A 5odqA-4lgnA:
undetectable		 5odqA-4lgnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mc0 PUTATIVE
SESQUITERPENE
CYCLASE

(Kitasatospora
setae) 		no annotation 4 ARG A 134
PRO A 135
PHE A 195
GLU A 189
 None
 1.30A 5odqA-4mc0A:
4.2		 5odqA-4mc0A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qjy GH127
BETA-L-ARABINOFURANO
SIDASE

(Geobacillus
stearothermophilus) 		PF07944
(Glyco_hydro_127) 		4 ARG A 130
ARG A 262
ALA A 246
PHE A 235
 None
 1.30A 5odqA-4qjyA:
undetectable		 5odqA-4qjyA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ras OXIDOREDUCTASE,
NAD-BINDING/IRON-SUL
FUR CLUSTER-BINDING
PROTEIN

(Nitratireductor
pacificus) 		PF12838
(Fer4_7)
PF13486
(Dehalogenase) 		4 ARG A  79
ARG A  78
ALA A  77
PRO A  76
 None
 1.23A 5odqA-4rasA:
undetectable		 5odqA-4rasA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru3 PUNCTURING PROTEIN
GP41

(Pseudomonas
virus SN) 		no annotation 4 ARG A  68
ALA A  38
PRO A  54
PHE A 125
 None
 1.37A 5odqA-4ru3A:
undetectable		 5odqA-4ru3A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvr E3 UBIQUITIN-PROTEIN
LIGASE UHRF2

(Homo sapiens) 		PF00628
(PHD)
PF12148
(TTD) 		4 ARG A 230
ARG A 310
ALA A 313
PRO A 231
 None
 1.40A 5odqA-4tvrA:
undetectable		 5odqA-4tvrA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xri PUTATIVE
UNCHARACTERIZED
PROTEIN

(Chaetomium
thermophilum) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		4 ARG A 321
ALA A 320
PHE A 316
GLU A 301
 None
 1.41A 5odqA-4xriA:
undetectable		 5odqA-4xriA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yvs CAPSID PROTEIN VP0

(Enterovirus A) 		PF00073
(Rhv) 		4 ARG C  55
ARG C 103
ALA C 246
PRO C  53
 None
 1.34A 5odqA-4yvsC:
undetectable		 5odqA-4yvsC:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0z AURONE SYNTHASE

(Coreopsis
grandiflora) 		PF00264
(Tyrosinase)
PF12142
(PPO1_DWL) 		4 ARG A  69
ARG A  70
ALA A  73
PRO A 171
 None
 1.21A 5odqA-4z0zA:
undetectable		 5odqA-4z0zA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zbz URACIL-DNA
GLYCOSYLASE

(Sulfurisphaera
tokodaii) 		PF03167
(UDG) 		4 ALA A 166
PRO A 165
PHE A  55
GLU A  48
 None
 0.90A 5odqA-4zbzA:
3.1		 5odqA-4zbzA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfl AMIDOHYDROLASE EGTC

(Mycolicibacterium
smegmatis) 		PF13522
(GATase_6) 		4 ARG A  60
ARG A  88
ALA A  86
PHE A 104
 None
4NK  A 301 (-3.5A)
None
None
 1.24A 5odqA-4zflA:
undetectable		 5odqA-4zflA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgj NITRILE HYDRATASE
BETA SUBUNIT

(Comamonas
testosteroni) 		PF02211
(NHase_beta) 		4 ALA B 161
PRO B 159
PHE B 198
GLU B 171
 None
 1.42A 5odqA-4zgjB:
undetectable		 5odqA-4zgjB:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ck3 PUTATIVE SIGNAL
RECOGNITION PARTICLE
PROTEIN

(Chaetomium
thermophilum) 		PF09439
(SRPRB) 		4 ARG B 234
ARG B 238
ALA B 239
PRO B 240
 None
 1.19A 5odqA-5ck3B:
3.3		 5odqA-5ck3B:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dgq PUTATIVE
ENDOGLUCANASE-RELATE
D PROTEIN

(Photobacterium
profundum) 		PF00759
(Glyco_hydro_9) 		4 ARG A 552
ALA A 537
PHE A 530
GLU A 531
 None
 1.30A 5odqA-5dgqA:
undetectable		 5odqA-5dgqA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5m ALPHA-CATENIN-LIKE
PROTEIN HMP-1

(Caenorhabditis
elegans) 		PF01044
(Vinculin) 		4 ARG A 554
ARG A 551
ALA A 552
PHE A 505
 None
 1.22A 5odqA-5h5mA:
undetectable		 5odqA-5h5mA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hmq 4-HYDROXYPHENYLPYRUV
ATE DIOXYGENASE

(Pseudomonas
putida) 		PF00903
(Glyoxalase)
PF01261
(AP_endonuc_2)
PF14696
(Glyoxalase_5) 		4 ARG A 494
ALA A 445
PRO A 496
GLU A 599
 None
None
None
MG  A 702 (-2.5A)
 1.35A 5odqA-5hmqA:
undetectable		 5odqA-5hmqA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ig2 SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Paraburkholderia
phymatum) 		PF00106
(adh_short) 		4 ARG A 214
ALA A 218
PHE A  98
GLU A 101
 None
 0.97A 5odqA-5ig2A:
3.8		 5odqA-5ig2A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 ARG A 272
ALA A 230
PRO A 271
GLU A 284
 None
 1.29A 5odqA-5kf7A:
2.9		 5odqA-5kf7A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mue ALPHA-TOCOPHEROL
TRANSFER PROTEIN

(Homo sapiens) 		PF00650
(CRAL_TRIO)
PF03765
(CRAL_TRIO_N) 		4 ARG A  54
ARG A  57
ALA A  58
PRO A 188
 None
 1.35A 5odqA-5mueA:
undetectable		 5odqA-5mueA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN

(Chaetomium
thermophilum) 		PF06427
(UDP-g_GGTase) 		4 ARG A 110
ALA A 112
PRO A 114
PHE A1129
 EDO  A1615 (-2.9A)
None
None
None
 1.34A 5odqA-5mzoA:
undetectable		 5odqA-5mzoA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfh METHIONYL-TRNA
SYNTHETASE, PUTATIVE

(Trypanosoma
brucei) 		no annotation 4 ALA A 544
PRO A 429
PHE A 431
GLU A 435
 None
 1.16A 5odqA-5nfhA:
2.8		 5odqA-5nfhA:
22.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT A

(Methanothermococcus
thermolithotrophicus) 		PF07992
(Pyr_redox_2)
PF13187
(Fer4_9) 		6 ARG A  81
ARG A  82
ALA A  85
PRO A  91
PHE A 137
GLU A 571
 None
 0.17A 5odqA-5odrA:
66.2		 5odqA-5odrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txe ATXE2

(Asticcacaulis
excentricus) 		PF00326
(Peptidase_S9) 		4 ARG A 133
ALA A  71
PRO A 132
GLU A 355
 None
 1.35A 5odqA-5txeA:
2.5		 5odqA-5txeA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u81 ACID CERAMIDASE
ISOFORM B

(Heterocephalus
glaber) 		no annotation 4 ARG A 298
ALA A 279
PRO A 278
GLU A 138
 None
 1.38A 5odqA-5u81A:
undetectable		 5odqA-5u81A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ugz PUTATIVE
THIOESTERASE

(Escherichia
coli) 		PF00975
(Thioesterase) 		4 ALA A 113
PRO A 110
PHE A  85
GLU A  86
 None
 1.43A 5odqA-5ugzA:
4.9		 5odqA-5ugzA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uif PS01740

(Pseudomonas sp.
UW4) 		no annotation 4 ARG A  68
ALA A  34
PRO A  35
GLU A 112
 None
 1.21A 5odqA-5uifA:
undetectable		 5odqA-5uifA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uyt ICE-BINDING PROTEIN

(Flavobacteriaceae
bacterium
3519-10) 		no annotation 4 ARG A 422
ALA A 303
PRO A 237
PHE A 385
 None
 1.17A 5odqA-5uytA:
undetectable		 5odqA-5uytA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xfl CATENIN ALPHA-2

(Mus musculus) 		no annotation 4 ARG A 549
ARG A 546
ALA A 547
PHE A 509
 None
 1.13A 5odqA-5xflA:
undetectable		 5odqA-5xflA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xra CANNABINOID RECEPTOR
1,FLAVODOXIN,CANNABI
NOID RECEPTOR 1

(Desulfovibrio
vulgaris;
Homo sapiens) 		PF00001
(7tm_1)
PF00258
(Flavodoxin_1) 		4 ARG A1131
ARG A1134
ALA A1133
PRO A1130
 None
 1.32A 5odqA-5xraA:
3.0		 5odqA-5xraA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu6 INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Cryptococcus
neoformans) 		PF06090
(Ins_P5_2-kin) 		4 ARG A 189
ALA A 190
PRO A 193
PHE A 180
 None
 1.25A 5odqA-5xu6A:
undetectable		 5odqA-5xu6A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhu MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Bos taurus) 		no annotation 4 ARG A 415
ALA A 414
PHE A 619
GLU A 422
 None
 1.26A 5odqA-6bhuA:
undetectable		 5odqA-6bhuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bwe PUTATIVE FIMBRIAL
ASSOCIATED
SORTASE-LIKE PROTEIN

(Corynebacterium
diphtheriae) 		no annotation 4 ARG A  60
ALA A  58
PRO A  57
GLU A  53
 None
 1.29A 5odqA-6bweA:
undetectable		 5odqA-6bweA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g21 PROBABLE FERULOYL
ESTERASE B-2

(Aspergillus
oryzae) 		no annotation 4 ARG A  83
ALA A 110
PRO A  77
GLU A 158
 None
 1.40A 5odqA-6g21A:
2.8		 5odqA-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g79 5-HYDROXYTRYPTAMINE
RECEPTOR 1B

(Homo sapiens) 		no annotation 4 ARG S 161
ARG S 165
ALA S 166
PRO S  83
 None
 1.33A 5odqA-6g79S:
undetectable		 5odqA-6g79S:
undetectable