SIMILAR PATTERNS OF AMINO ACIDS FOR 5ODQ_A_ACTA702

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR CWF11

(Schizosaccharomyces
pombe) 		PF13087
(AAA_12)
PF16399
(Aquarius_N) 		4 LYS X 218
VAL X 219
LYS X 214
LYS X 205
 None
 1.49A 5odqA-3jb9X:
undetectable		 5odqA-3jb9X:
19.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5odr HETERODISULFIDE
REDUCTASE, SUBUNIT A

(Methanothermococcus
thermolithotrophicus) 		PF07992
(Pyr_redox_2)
PF13187
(Fer4_9) 		4 LYS A 368
VAL A 369
LYS A 377
SER A 418
 None
 0.98A 5odqA-5odrA:
66.2		 5odqA-5odrA:
100.00