SIMILAR PATTERNS OF AMINO ACIDS FOR 5ODI_G_ACTG702
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aun | PR-5D (Nicotianatabacum) |
PF00314(Thaumatin) | 3 | GLY A 48THR A 50ASN A 106 | None | 0.54A | 5odiG-1aunA:undetectable | 5odiG-1aunA:16.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e0t | PYRUVATE KINASE (Escherichiacoli) |
PF00224(PK)PF02887(PK_C) | 3 | GLY A 454THR A 461ASN A 463 | None | 0.68A | 5odiG-1e0tA:0.2 | 5odiG-1e0tA:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e5d | RUBREDOXIN:OXYGENOXIDOREDUCTASE (Desulfovibriogigas) |
PF00258(Flavodoxin_1)PF00753(Lactamase_B) | 3 | GLY A 281THR A 283ASN A 253 | None | 0.53A | 5odiG-1e5dA:6.6 | 5odiG-1e5dA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1flc | HAEMAGGLUTININ-ESTERASE-FUSIONGLYCOPROTEIN (Influenza Cvirus) |
PF02710(Hema_HEFG)PF03996(Hema_esterase) | 3 | GLY A 172THR A 170ASN A 176 | None | 0.70A | 5odiG-1flcA:0.5 | 5odiG-1flcA:22.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnz | BARK AGGLUTININ I,POLYPEPTIDE A (Robiniapseudoacacia) |
PF00139(Lectin_legB) | 3 | GLY A 88THR A 214ASN A 224 | None | 0.71A | 5odiG-1fnzA:undetectable | 5odiG-1fnzA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i5g | TRYPAREDOXIN II (Crithidiafasciculata) |
PF13905(Thioredoxin_8) | 3 | GLY A 29THR A 31ASN A 63 | None | 0.68A | 5odiG-1i5gA:1.4 | 5odiG-1i5gA:13.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jfl | ASPARTATE RACEMASE (Pyrococcushorikoshii) |
PF01177(Asp_Glu_race) | 3 | GLY A 193THR A 124ASN A 83 | None | 0.62A | 5odiG-1jflA:5.8 | 5odiG-1jflA:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jmc | PROTEIN (REPLICATIONPROTEIN A (RPA)) (Homo sapiens) |
PF01336(tRNA_anti-codon)PF16900(REPA_OB_2) | 3 | GLY A 260THR A 279ASN A 281 | None | 0.70A | 5odiG-1jmcA:undetectable | 5odiG-1jmcA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mex | FAB 29G12 HEAVYCHAIN (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | GLY H 65THR H 68ASN H 82 | None | 0.63A | 5odiG-1mexH:undetectable | 5odiG-1mexH:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o73 | TRYPAREDOXIN (Trypanosomabrucei) |
PF13905(Thioredoxin_8) | 3 | GLY A 28THR A 30ASN A 62 | None | 0.64A | 5odiG-1o73A:undetectable | 5odiG-1o73A:12.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pcv | OSMOTIN (Nicotianatabacum) |
PF00314(Thaumatin) | 3 | GLY A 47THR A 49ASN A 105 | None | 0.48A | 5odiG-1pcvA:undetectable | 5odiG-1pcvA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qmo | MANNOSE BINDINGLECTIN, FRILMANNOSE BINDINGLECTIN, FRIL (Lablabpurpureus;Lablabpurpureus) |
PF00139(Lectin_legB)PF00139(Lectin_legB) | 3 | GLY A 87THR E 227ASN E 234 | None | 0.48A | 5odiG-1qmoA:undetectable | 5odiG-1qmoA:9.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4p | SHIGA-LIKE TOXINTYPE II A SUBUNIT (Escherichiacoli) |
PF00161(RIP) | 3 | GLY A 102THR A 104ASN A 87 | None | 0.55A | 5odiG-1r4pA:undetectable | 5odiG-1r4pA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sqh | HYPOTHETICAL PROTEINCG14615-PA (Drosophilamelanogaster) |
PF08445(FR47) | 3 | GLY A 143THR A 145ASN A 302 | None | 0.59A | 5odiG-1sqhA:undetectable | 5odiG-1sqhA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgw | 4-DIPHOSPHOCYTIDYL-2C-METHYL-D-ERYTHRITOL SYNTHASE (Neisseriagonorrhoeae) |
PF01128(IspD) | 3 | GLY A 89THR A 85ASN A 77 | None | 0.66A | 5odiG-1vgwA:3.3 | 5odiG-1vgwA:16.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wno | CHITINASE (Aspergillusfumigatus) |
PF00704(Glyco_hydro_18) | 3 | GLY A 272THR A 233ASN A 229 | None | 0.69A | 5odiG-1wnoA:1.8 | 5odiG-1wnoA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wod | MODA (Escherichiacoli) |
PF13531(SBP_bac_11) | 3 | GLY A 229THR A 231ASN A 83 | None | 0.65A | 5odiG-1wodA:undetectable | 5odiG-1wodA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wzo | HPCE (Thermusthermophilus) |
PF01557(FAA_hydrolase) | 3 | GLY A 44THR A 42ASN A 75 | None | 0.68A | 5odiG-1wzoA:undetectable | 5odiG-1wzoA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygu | LEUKOCYTE COMMONANTIGEN (Homo sapiens) |
PF00102(Y_phosphatase) | 3 | GLY A 822THR A 721ASN A 818 | None | 0.67A | 5odiG-1yguA:undetectable | 5odiG-1yguA:21.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ytk | NICOTINATEPHOSPHORIBOSYLTRANSFERASE FROMTHERMOPLASMAACIDOPHILUM (Thermoplasmaacidophilum) |
PF01729(QRPTase_C) | 3 | GLY A 77THR A 55ASN A 53 | None | 0.63A | 5odiG-1ytkA:2.1 | 5odiG-1ytkA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z3q | THAUMATIN-LIKEPROTEIN (Musa acuminata) |
PF00314(Thaumatin) | 3 | GLY A 46THR A 48ASN A 104 | None | 0.56A | 5odiG-1z3qA:undetectable | 5odiG-1z3qA:15.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bpa | PROTEIN (SUBUNIT OFBACTERIOPHAGEPHIX174) (Escherichiavirus phiX174) |
PF02306(Phage_G) | 3 | GLY 2 52THR 2 151ASN 2 149 | None | 0.69A | 5odiG-2bpa2:undetectable | 5odiG-2bpa2:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ctx | ALPHA-COBRATOXIN (Naja naja) |
PF00087(Toxin_TOLIP) | 3 | GLY A 40THR A 22ASN A 63 | None | 0.67A | 5odiG-2ctxA:undetectable | 5odiG-2ctxA:7.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d3r | LECTIN ALPHA CHAIN (Cratyliaargentea) |
PF00139(Lectin_legB) | 3 | GLY A 208THR A 97ASN A 104 | None | 0.60A | 5odiG-2d3rA:undetectable | 5odiG-2d3rA:16.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dpg | GLUCOSE 6-PHOSPHATEDEHYDROGENASE (Leuconostocmesenteroides) |
PF00479(G6PD_N)PF02781(G6PD_C) | 3 | GLY A 231THR A 314ASN A 312 | None | 0.64A | 5odiG-2dpgA:2.8 | 5odiG-2dpgA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gdf | LECTIN (Diocleaviolacea) |
PF00139(Lectin_legB) | 3 | GLY A 209THR A 97ASN A 104 | None | 0.68A | 5odiG-2gdfA:undetectable | 5odiG-2gdfA:16.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h7z | IRDITOXIN SUBUNIT B (Boigairregularis) |
PF00087(Toxin_TOLIP) | 3 | GLY B 52THR B 36ASN B 75 | None | 0.60A | 5odiG-2h7zB:undetectable | 5odiG-2h7zB:7.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuc | ALKALINE PHOSPHATASE (Antarcticbacterium TAB5) |
PF00245(Alk_phosphatase) | 3 | GLY B 198THR B 200ASN B 195 | None | 0.71A | 5odiG-2iucB:undetectable | 5odiG-2iucB:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jfw | GLUTAMATE RACEMASE (Enterococcusfaecium) |
PF01177(Asp_Glu_race) | 3 | GLY A 187THR A 121ASN A 78 | NoneTLA A1272 (-3.9A)TLA A1272 (-4.3A) | 0.68A | 5odiG-2jfwA:4.3 | 5odiG-2jfwA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jfw | GLUTAMATE RACEMASE (Enterococcusfaecium) |
PF01177(Asp_Glu_race) | 3 | GLY A 187THR A 189ASN A 78 | NoneNoneTLA A1272 (-4.3A) | 0.53A | 5odiG-2jfwA:4.3 | 5odiG-2jfwA:19.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jgv | TAGATOSE-6-PHOSPHATEKINASE (Staphylococcusaureus) |
PF00294(PfkB) | 3 | GLY A 106THR A 87ASN A 8 | None | 0.69A | 5odiG-2jgvA:5.4 | 5odiG-2jgvA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jod | PITUITARY ADENYLATECYCLASE-ACTIVATINGPOLYPEPTIDE TYPE IRECEPTOR (Homo sapiens) |
PF02793(HRM) | 3 | GLY A 70THR A 98ASN A 96 | None | 0.69A | 5odiG-2jodA:undetectable | 5odiG-2jodA:10.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ow4 | CANAVALIA MARITIMALECTIN (Canavalia rosea) |
PF00139(Lectin_legB) | 3 | GLY A 209THR A 97ASN A 104 | None | 0.65A | 5odiG-2ow4A:undetectable | 5odiG-2ow4A:16.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rg2 | CHOLOYLGLYCINEHYDROLASE (Clostridiumperfringens) |
PF02275(CBAH) | 3 | GLY A 96THR A 98ASN A 125 | None | 0.65A | 5odiG-2rg2A:undetectable | 5odiG-2rg2A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uzh | 2C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Mycolicibacteriumsmegmatis) |
PF02542(YgbB) | 3 | GLY A 141THR A 133ASN A 104 | NoneCDP A1158 (-2.7A)None | 0.67A | 5odiG-2uzhA:undetectable | 5odiG-2uzhA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vl7 | XPD (Sulfurisphaeratokodaii) |
PF06733(DEAD_2)PF13307(Helicase_C_2) | 3 | GLY A 26THR A 28ASN A 337 | None | 0.58A | 5odiG-2vl7A:2.2 | 5odiG-2vl7A:22.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vz9 | FATTY ACID SYNTHASE (Sus scrofa) |
PF00107(ADH_zinc_N)PF00109(ketoacyl-synt)PF00698(Acyl_transf_1)PF02801(Ketoacyl-synt_C)PF08242(Methyltransf_12)PF08659(KR)PF14765(PS-DH)PF16197(KAsynt_C_assoc) | 3 | GLY A1700THR A1698ASN A1722 | NAP A3001 (-4.0A)NoneNone | 0.60A | 5odiG-2vz9A:undetectable | 5odiG-2vz9A:12.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w3p | BENZOYL-COA-DIHYDRODIOL LYASE (Paraburkholderiaxenovorans) |
PF00378(ECH_1) | 3 | GLY A 177THR A 521ASN A 115 | BME A 601 (-3.7A)NoneNone | 0.68A | 5odiG-2w3pA:2.1 | 5odiG-2w3pA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsk | GLYCOGEN DEBRANCHINGENZYME (Escherichiacoli) |
PF00128(Alpha-amylase)PF02922(CBM_48) | 3 | GLY A 59THR A 24ASN A 22 | None | 0.68A | 5odiG-2wskA:2.5 | 5odiG-2wskA:22.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wzm | ALDO-KETO REDUCTASE (Mycolicibacteriumsmegmatis) |
PF00248(Aldo_ket_red) | 3 | GLY A 30THR A 54ASN A 60 | NA7 A1284 ( 3.8A)NoneNone | 0.69A | 5odiG-2wzmA:undetectable | 5odiG-2wzmA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zau | SELENIDE, WATERDIKINASE (Aquifexaeolicus) |
PF00586(AIRS)PF02769(AIRS_C) | 3 | GLY A 296THR A 169ASN A 202 | None | 0.71A | 5odiG-2zauA:undetectable | 5odiG-2zauA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zux | YESW PROTEIN (Bacillussubtilis) |
no annotation | 3 | GLY A 186THR A 141ASN A 175 | RAM A 641 ( 4.4A)NoneNone | 0.68A | 5odiG-2zuxA:undetectable | 5odiG-2zuxA:24.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a8u | OMEGA-AMINOACID--PYRUVATEAMINOTRANSFERASE (Pseudomonasputida) |
PF00202(Aminotran_3) | 3 | GLY X 63THR X 61ASN X 292 | None | 0.63A | 5odiG-3a8uX:undetectable | 5odiG-3a8uX:22.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3db2 | PUTATIVENADPH-DEPENDENTOXIDOREDUCTASE (Desulfitobacteriumhafniense) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 3 | GLY A 175THR A 214ASN A 212 | None | 0.66A | 5odiG-3db2A:undetectable | 5odiG-3db2A:19.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd5 | SELENIDE, WATERDIKINASE 1 (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 3 | GLY A 322THR A 200ASN A 248 | None | 0.69A | 5odiG-3fd5A:undetectable | 5odiG-3fd5A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g7m | XYLANASE INHIBITORTL-XI (Triticumaestivum) |
PF00314(Thaumatin) | 3 | GLY A 50THR A 52ASN A 108 | None | 0.45A | 5odiG-3g7mA:undetectable | 5odiG-3g7mA:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ide | CAPSID PROTEIN VP2 (Infectiouspancreaticnecrosis virus) |
PF01766(Birna_VP2) | 3 | GLY A 339THR A 236ASN A 234 | None | 0.70A | 5odiG-3ideA:undetectable | 5odiG-3ideA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j8f | POLIOVIRUS RECEPTOR (Homo sapiens) |
PF07686(V-set)PF08205(C2-set_2) | 3 | GLY 7 216THR 7 239ASN 7 237 | NAG 7 513 (-3.8A)NoneNAG 7 513 (-1.9A) | 0.59A | 5odiG-3j8f7:undetectable | 5odiG-3j8f7:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9f | POLIOVIRUS RECEPTOR (Homo sapiens) |
PF08205(C2-set_2) | 3 | GLY 8 216THR 8 239ASN 8 237 | NAG 8 305 (-4.0A)NoneNAG 8 305 (-1.7A) | 0.67A | 5odiG-3j9f8:undetectable | 5odiG-3j9f8:9.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jca | INTEGRASE (Mouse mammarytumor virus) |
PF00552(IN_DBD_C)PF00665(rve)PF02022(Integrase_Zn) | 3 | GLY A 146THR A 121ASN A 123 | None | 0.65A | 5odiG-3jcaA:undetectable | 5odiG-3jcaA:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kls | EXOTOXIN 1 (Staphylococcusaureus) |
PF02876(Stap_Strp_tox_C)PF09199(SSL_OB) | 3 | GLY X 187THR X 227ASN X 229 | None | 0.61A | 5odiG-3klsX:undetectable | 5odiG-3klsX:16.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3o | ALPHA-SUBUNIT2-HYDROXYISOCAPROYL-COA DEHYDRATASE (Clostridioidesdifficile) |
PF06050(HGD-D) | 3 | GLY A 211THR A 286ASN A 284 | None | 0.65A | 5odiG-3o3oA:5.2 | 5odiG-3o3oA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oq3 | IFN-ALPHA/BETABINDING PROTEIN C12R (Ectromeliavirus) |
PF00047(ig)PF13895(Ig_2) | 3 | GLY B 242THR B 300ASN B 298 | None | 0.65A | 5odiG-3oq3B:undetectable | 5odiG-3oq3B:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psf | TRANSCRIPTIONELONGATION FACTORSPT6 (Saccharomycescerevisiae) |
PF14635(HHH_7)PF14639(YqgF)PF14641(HTH_44)PF14878(DLD) | 3 | GLY A 758THR A 820ASN A 817 | None | 0.68A | 5odiG-3psfA:3.8 | 5odiG-3psfA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3psi | TRANSCRIPTIONELONGATION FACTORSPT6 (Saccharomycescerevisiae) |
PF14635(HHH_7)PF14639(YqgF)PF14641(HTH_44)PF14878(DLD) | 3 | GLY A 758THR A 820ASN A 817 | None | 0.62A | 5odiG-3psiA:4.0 | 5odiG-3psiA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s9f | TRYPAREDOXIN (Leishmaniamajor) |
PF13905(Thioredoxin_8) | 3 | GLY A 28THR A 30ASN A 62 | None | 0.60A | 5odiG-3s9fA:undetectable | 5odiG-3s9fA:13.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t3a | KILLER CELLLECTIN-LIKE RECEPTORSUBFAMILY B MEMBER1A (Mus musculus) |
PF00059(Lectin_C) | 3 | GLY A 182THR A 184ASN A 203 | None | 0.69A | 5odiG-3t3aA:undetectable | 5odiG-3t3aA:12.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u0o | SELENIDE, WATERDIKINASE (Escherichiacoli) |
PF00586(AIRS)PF02769(AIRS_C) | 3 | GLY A 303THR A 177ASN A 210 | None | 0.70A | 5odiG-3u0oA:undetectable | 5odiG-3u0oA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wcs | ERYTHROAGGLUTININ (Phaseolusvulgaris) |
PF00139(Lectin_legB) | 3 | GLY A 108THR A 234ASN A 244 | None | 0.69A | 5odiG-3wcsA:undetectable | 5odiG-3wcsA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zs3 | THAUMATIN-LIKEPROTEIN (Malus domestica) |
PF00314(Thaumatin) | 3 | GLY A 53THR A 55ASN A 113 | NoneACT A1227 (-3.1A)None | 0.49A | 5odiG-3zs3A:undetectable | 5odiG-3zs3A:16.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b98 | BETA-ALANINE--PYRUVATE TRANSAMINASE (Pseudomonasaeruginosa) |
PF00202(Aminotran_3) | 3 | GLY A 64THR A 62ASN A 292 | None | 0.62A | 5odiG-4b98A:undetectable | 5odiG-4b98A:22.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bi9 | 3-KETOACYL-COATHIOLASE, PUTATIVE (Trypanosomabrucei) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 3 | GLY A 123THR A 390ASN A 422 | None | 0.70A | 5odiG-4bi9A:undetectable | 5odiG-4bi9A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bs9 | TRUD (unculturedProchloron sp.06037A) |
PF02624(YcaO) | 3 | GLY A 371THR A 374ASN A 220 | None | 0.54A | 5odiG-4bs9A:3.6 | 5odiG-4bs9A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cab | CATALASE (Deinococcusradiodurans) |
PF00199(Catalase)PF06628(Catalase-rel) | 3 | GLY A 89THR A 328ASN A 330 | None | 0.71A | 5odiG-4cabA:undetectable | 5odiG-4cabA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dqv | PROBABLE PEPTIDESYNTHETASE NRP(PEPTIDE SYNTHASE) (Mycobacteriumtuberculosis) |
PF07993(NAD_binding_4) | 3 | GLY A 256THR A 193ASN A 158 | None | 0.63A | 5odiG-4dqvA:5.3 | 5odiG-4dqvA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h20 | HEAVY CHAIN OF FABFRAGMENT FROM THE ANTI-RICINMONOCLONAL ANTIBODYRAC18 (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | GLY H 66THR H 69ASN H 84 | None | 0.68A | 5odiG-4h20H:undetectable | 5odiG-4h20H:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hwt | THREONINE--TRNALIGASE, CYTOPLASMIC (Homo sapiens) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 3 | GLY A 471THR A 407ASN A 445 | None | 0.62A | 5odiG-4hwtA:2.2 | 5odiG-4hwtA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iss | ALLOPHANATEHYDROLASE (Kluyveromyceslactis) |
PF01425(Amidase) | 3 | GLY A 138THR A 140ASN A 122 | None | 0.57A | 5odiG-4issA:undetectable | 5odiG-4issA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j8r | HEAVY CHAIN OF POM2FAB (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 3 | GLY B 65THR B 68ASN B 82 | None | 0.70A | 5odiG-4j8rB:undetectable | 5odiG-4j8rB:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5h | VVTL1 (Vitis vinifera) |
PF00314(Thaumatin) | 3 | GLY A 70THR A 72ASN A 128 | None | 0.56A | 5odiG-4l5hA:undetectable | 5odiG-4l5hA:15.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mkm | PUTATIVE SURFACEANCHORED PROTEIN (Clostridiumperfringens) |
no annotation | 3 | GLY A 231THR A 229ASN A 200 | None | 0.62A | 5odiG-4mkmA:undetectable | 5odiG-4mkmA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n01 | PERIPLASMIC BINDINGPROTEIN (Veillonellaparvula) |
PF01497(Peripla_BP_2) | 3 | GLY A 314THR A 317ASN A 165 | None | 0.61A | 5odiG-4n01A:3.9 | 5odiG-4n01A:18.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q6r | SPHINGOSINE-1-PHOSPHATE LYASE 1 (Homo sapiens) |
PF00282(Pyridoxal_deC) | 3 | GLY A 521THR A 519ASN A 465 | NoneGOL A 902 (-4.5A)GOL A 902 (-4.3A) | 0.65A | 5odiG-4q6rA:undetectable | 5odiG-4q6rA:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2f | EXTRACELLULARSOLUTE-BINDINGPROTEIN FAMILY 1 (Pseudarthrobacterchlorophenolicus) |
PF01547(SBP_bac_1) | 3 | GLY A 117THR A 115ASN A 328 | LB2 A 501 (-3.1A)NoneLB2 A 501 (-3.0A) | 0.71A | 5odiG-4r2fA:undetectable | 5odiG-4r2fA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rvp | SUPEROXIDE DISMUTASE (Sedum alfredii) |
PF00080(Sod_Cu) | 3 | GLY A 39THR A 41ASN A 114 | None | 0.70A | 5odiG-4rvpA:undetectable | 5odiG-4rvpA:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uhm | OMEGA AMINOACID-PYRUVATEAMINOTRANSFERASE (Pseudomonas sp.) |
PF00202(Aminotran_3) | 3 | GLY A 64THR A 62ASN A 292 | None | 0.59A | 5odiG-4uhmA:undetectable | 5odiG-4uhmA:21.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1u | LYND (Lyngbyaaestuarii) |
PF02624(YcaO) | 3 | GLY A 364THR A 367ASN A 214 | None | 0.67A | 5odiG-4v1uA:3.7 | 5odiG-4v1uA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xxn | ESX-1SECRETION-ASSOCIATEDPROTEIN ESPB (Mycobacteriumtuberculosis) |
no annotation | 3 | GLY A 126THR A 124ASN A 265 | None | 0.67A | 5odiG-4xxnA:undetectable | 5odiG-4xxnA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y05 | KINESIN-LIKE PROTEINKIF2C (Homo sapiens) |
PF00225(Kinesin) | 3 | GLY A 339THR A 335ASN A 556 | None | 0.62A | 5odiG-4y05A:undetectable | 5odiG-4y05A:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aa6 | VANADIUM-DEPENDENTBROMOPEROXIDASE 2 (Ascophyllumnodosum) |
no annotation | 3 | GLY A 74THR A 76ASN A 158 | None | 0.65A | 5odiG-5aa6A:undetectable | 5odiG-5aa6A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b6t | GLYCOSYL HYDROLASEFAMILY 62 PROTEIN (Coprinopsiscinerea) |
PF03664(Glyco_hydro_62) | 3 | GLY A 198THR A 200ASN A 190 | None | 0.68A | 5odiG-5b6tA:undetectable | 5odiG-5b6tA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bxp | LACTO-N-BIOSIDASE (Bifidobacteriumbifidum) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b)PF14200(RicinB_lectin_2) | 3 | GLY A 345THR A 347ASN A 382 | None | 0.62A | 5odiG-5bxpA:4.1 | 5odiG-5bxpA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej3 | ENDO-1,4-BETA-XYLANASE B (Streptomyceslividans) |
PF00457(Glyco_hydro_11) | 3 | GLY A 32THR A 2ASN A 12 | None | 0.65A | 5odiG-5ej3A:undetectable | 5odiG-5ej3A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gje | LOW-DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 6 (Homo sapiens) |
PF00058(Ldl_recept_b)PF14670(FXa_inhibition) | 3 | GLY B1049THR B1041ASN B1039 | NoneNAG B1307 (-2.9A)NAG B1307 (-1.7A) | 0.65A | 5odiG-5gjeB:undetectable | 5odiG-5gjeB:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5glg | FUMARATE REDUCTASE 2 (Saccharomycescerevisiae) |
PF00890(FAD_binding_2) | 3 | GLY A 254THR A 252ASN A 73 | NoneFAD A 602 (-4.1A)FAD A 602 (-4.2A) | 0.70A | 5odiG-5glgA:13.2 | 5odiG-5glgA:24.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i8i | UREA AMIDOLYASE (Kluyveromyceslactis) |
PF00289(Biotin_carb_N)PF01425(Amidase)PF02626(CT_A_B)PF02682(CT_C_D)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 3 | GLY A 138THR A 140ASN A 122 | None | 0.58A | 5odiG-5i8iA:4.0 | 5odiG-5i8iA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lnq | 3-KETOACYL-COATHIOLASE-LIKEPROTEIN (Leishmaniamexicana) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 3 | GLY A 126THR A 393ASN A 425 | None | 0.63A | 5odiG-5lnqA:undetectable | 5odiG-5lnqA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8p | S-LAYER PROTEIN (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 3 | GLY A 424THR A 422ASN A 451 | None | 0.69A | 5odiG-5n8pA:undetectable | 5odiG-5n8pA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8p | S-LAYER PROTEIN (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 3 | GLY A 473THR A 439ASN A 435 | None | 0.70A | 5odiG-5n8pA:undetectable | 5odiG-5n8pA:19.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n97 | S-LAYER PROTEIN RSAA (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 3 | GLY A 424THR A 422ASN A 451 | None | 0.69A | 5odiG-5n97A:undetectable | 5odiG-5n97A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n97 | S-LAYER PROTEIN RSAA (Caulobactervibrioides) |
PF00353(HemolysinCabind) | 3 | GLY A 473THR A 439ASN A 435 | None | 0.71A | 5odiG-5n97A:undetectable | 5odiG-5n97A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nd1 | CAPSID PROTEIN (Rosellinianecatrixquadrivirus 1) |
no annotation | 3 | GLY B 148THR B 125ASN B 123 | None | 0.70A | 5odiG-5nd1B:undetectable | 5odiG-5nd1B:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odo | ISOMERASE (Rhodococcuserythropolis) |
no annotation | 3 | GLY A 221THR A 223ASN A 79 | MG A 610 ( 4.7A) MG A 610 ( 4.7A)None | 0.71A | 5odiG-5odoA:8.0 | 5odiG-5odoA:21.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5odr | HETERODISULFIDEREDUCTASE, SUBUNIT A (Methanothermococcusthermolithotrophicus) |
PF07992(Pyr_redox_2)PF13187(Fer4_9) | 3 | GLY A 141THR A 143ASN A 229 | None | 0.10A | 5odiG-5odrA:63.0 | 5odiG-5odrA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v5s | OUTER MEMBRANEPROTEIN TOLC (Escherichiacoli) |
PF02321(OEP) | 3 | GLY A 59THR A 266ASN A 61 | None | 0.60A | 5odiG-5v5sA:undetectable | 5odiG-5v5sA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vkq | NO MECHANORECEPTORPOTENTIAL C ISOFORML (Drosophilamelanogaster) |
PF00023(Ank)PF00520(Ion_trans)PF12796(Ank_2)PF13637(Ank_4) | 3 | GLY A 827THR A 829ASN A 859 | None | 0.59A | 5odiG-5vkqA:undetectable | 5odiG-5vkqA:17.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vvm | CADHERIN-23 (Homo sapiens) |
no annotation | 3 | GLY A2215THR A2174ASN A2172 | None | 0.66A | 5odiG-5vvmA:undetectable | 5odiG-5vvmA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6x | MRNA CAPPING ENZYMEP5 (Rice dwarfvirus) |
no annotation | 3 | GLY C 672THR C 675ASN C 700 | None | 0.69A | 5odiG-5x6xC:undetectable | 5odiG-5x6xC:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bwt | THIOREDOXINREDUCTASE (Francisellatularensis) |
no annotation | 3 | GLY A 97THR A 82ASN A 84 | None | 0.56A | 5odiG-6bwtA:18.8 | 5odiG-6bwtA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6et9 | ACETYL-COAACETYLTRANSFERASETHIOLASE (Methanothermococcusthermolithotrophicus) |
no annotation | 3 | GLY A 88THR A 341ASN A 375 | None | 0.71A | 5odiG-6et9A:undetectable | 5odiG-6et9A:undetectable |