SIMILAR PATTERNS OF AMINO ACIDS FOR 5OAJ_E_TKTE601
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b97 | RESTRICTIONENDONUCLEASE ECORV (Escherichiacoli) |
PF09233(Endonuc-EcoRV) | 4 | TRP A 216TYR A 230TYR A 110ARG A 115 | None | 1.48A | 5oajD-1b97A:0.05oajE-1b97A:0.0 | 5oajD-1b97A:20.775oajE-1b97A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nez | H-2 CLASS IHISTOCOMPATIBILITYANTIGEN, TLA(C)ALPHA CHAIN (Mus musculus) |
PF00129(MHC_I)PF07654(C1-set) | 4 | TRP A 133TYR A 123PHE A 73TYR A 152 | None | 1.36A | 5oajD-1nezA:0.05oajE-1nezA:0.0 | 5oajD-1nezA:21.755oajE-1nezA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p75 | THYMIDINE KINASE (Equidalphaherpesvirus4) |
PF00693(Herpes_TK) | 4 | CYH A 117PHE A 137TYR A 29ARG A 27 | None | 0.94A | 5oajD-1p75A:0.05oajE-1p75A:0.0 | 5oajD-1p75A:20.775oajE-1p75A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tr1 | BETA-GLUCOSIDASE A (Paenibacilluspolymyxa) |
PF00232(Glyco_hydro_1) | 4 | GLU A 405TRP A 326CYH A 169TYR A 296 | GOL A2000 (-2.6A)NoneNoneGOL A2000 (-4.0A) | 1.46A | 5oajD-1tr1A:0.05oajE-1tr1A:0.0 | 5oajD-1tr1A:22.315oajE-1tr1A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a30 | DEOXYCYTIDINE KINASE (Homo sapiens) |
PF01712(dNK) | 4 | GLU A 27TRP A 215CYH A 101PHE A 225 | None | 1.45A | 5oajD-2a30A:0.05oajE-2a30A:0.0 | 5oajD-2a30A:18.755oajE-2a30A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gf0 | GTP-BINDING PROTEINDI-RAS1 (Homo sapiens) |
PF00071(Ras) | 4 | GLU A 159CYH A 123TYR A 155PHE A 146 | None | 1.30A | 5oajD-2gf0A:0.05oajE-2gf0A:0.0 | 5oajD-2gf0A:21.225oajE-2gf0A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zai | OLIGOSACCHARYLTRANSFERASE STT3SUBUNIT RELATEDPROTEIN (Pyrococcusfuriosus) |
no annotation | 4 | GLU A 952PHE A 727TYR A 955ARG A 762 | NoneNoneNone CL A 5 (-3.6A) | 1.39A | 5oajD-2zaiA:0.05oajE-2zaiA:0.0 | 5oajD-2zaiA:18.315oajE-2zaiA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dla | GLUTAMINE-DEPENDENTNAD(+) SYNTHETASE (Mycobacteriumtuberculosis) |
PF00795(CN_hydrolase)PF02540(NAD_synthase) | 4 | GLU A 237CYH A 176TYR A 58ARG A 209 | NoneONL A 800 (-1.6A)GOL A 805 (-4.5A)ONL A 800 ( 4.8A) | 1.13A | 5oajD-3dlaA:0.05oajE-3dlaA:0.0 | 5oajD-3dlaA:17.385oajE-3dlaA:17.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thc | BETA-GALACTOSIDASE (Homo sapiens) |
PF01301(Glyco_hydro_35)PF13364(BetaGal_dom4_5) | 4 | GLU A 129TRP A 273TYR A 485TYR A 270 | GAL A 900 (-2.8A)GAL A 900 ( 4.9A)NoneNone | 1.20A | 5oajD-3thcA:0.05oajE-3thcA:0.0 | 5oajD-3thcA:16.805oajE-3thcA:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tmp | OTUDOMAIN-CONTAININGPROTEIN 5 (Homo sapiens) |
PF02338(OTU) | 4 | GLU A 264CYH A 278TYR A 269TYR A 181 | NoneSEP A 177 ( 4.8A)SEP A 177 ( 4.9A)SEP A 177 ( 4.1A) | 1.27A | 5oajD-3tmpA:undetectable5oajE-3tmpA:undetectable | 5oajD-3tmpA:19.545oajE-3tmpA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wn6 | ALPHA-AMYLASE (Oryza sativa) |
PF00128(Alpha-amylase)PF07821(Alpha-amyl_C2) | 4 | GLU A 39TRP A 43PHE A 351TYR A 347 | None | 0.93A | 5oajD-3wn6A:undetectable5oajE-3wn6A:undetectable | 5oajD-3wn6A:18.025oajE-3wn6A:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wov | OLIGOSACCHARYLTRANSFERASE (Pyrococcusabyssi) |
no annotation | 4 | GLU A 958PHE A 735TYR A 961ARG A 770 | None | 1.46A | 5oajD-3wovA:undetectable5oajE-3wovA:undetectable | 5oajD-3wovA:17.905oajE-3wovA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zth | STU0660 (Streptococcusthermophilus) |
PF16813(Cas_St_Csn2) | 4 | GLU A 294CYH A 223PHE A 218TYR A 215 | None | 1.39A | 5oajD-3zthA:undetectable5oajE-3zthA:undetectable | 5oajD-3zthA:20.665oajE-3zthA:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gl2 | INTERFERON-INDUCEDHELICASE CDOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF00271(Helicase_C)PF04851(ResIII)PF11648(RIG-I_C-RD) | 4 | GLU A 602CYH A 962CYH A 964PHE A 987 | None ZN A1102 (-2.3A) ZN A1102 (-2.1A)None | 1.41A | 5oajD-4gl2A:undetectable5oajE-4gl2A:undetectable | 5oajD-4gl2A:15.685oajE-4gl2A:15.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jrn | RHOPTRY KINASEFAMILY PROTEIN (Toxoplasmagondii) |
PF14531(Kinase-like) | 4 | CYH A 198TYR A 388PHE A 424ARG A 321 | None | 1.29A | 5oajD-4jrnA:undetectable5oajE-4jrnA:undetectable | 5oajD-4jrnA:20.165oajE-4jrnA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ka8 | OLIGOPEPTIDASE A (Arabidopsisthaliana) |
PF01432(Peptidase_M3) | 4 | TYR A 612PHE A 644TYR A 443ARG A 439 | None | 1.39A | 5oajD-4ka8A:undetectable5oajE-4ka8A:undetectable | 5oajD-4ka8A:16.575oajE-4ka8A:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m0v | EXONUCLEASE SUBUNITSBCD (Escherichiacoli) |
PF00149(Metallophos)PF12320(SbcD_C) | 4 | GLU A 310CYH A 249PHE A 15TYR A 16 | None | 1.43A | 5oajD-4m0vA:undetectable5oajE-4m0vA:undetectable | 5oajD-4m0vA:21.115oajE-4m0vA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qdf | 3-KETOSTEROID9ALPHA-HYDROXYLASEOXYGENASE (Rhodococcusrhodochrous) |
PF00355(Rieske) | 4 | GLU B 335CYH B 169TYR B 334PHE B 23 | NoneNoneNonePO4 B 404 (-4.8A) | 1.48A | 5oajD-4qdfB:undetectable5oajE-4qdfB:undetectable | 5oajD-4qdfB:18.815oajE-4qdfB:18.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qlx | NITROREDUCTASEFAMILY PROTEIN (Lactobacillusplantarum) |
PF00881(Nitroreductase) | 4 | GLU A 131CYH A 51TYR A 101PHE A 137 | NoneKTC A 302 (-3.4A)NoneKTC A 302 (-4.8A) | 1.33A | 5oajD-4qlxA:undetectable5oajE-4qlxA:undetectable | 5oajD-4qlxA:18.495oajE-4qlxA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xqe | HOMOSPERMIDINESYNTHASE (Blastochlorisviridis) |
PF03435(Sacchrp_dh_NADP)PF16653(Sacchrp_dh_C) | 4 | GLU A 243CYH A 264TYR A 136ARG A 318 | NoneNoneNoneSO4 A 502 (-2.9A) | 1.25A | 5oajD-4xqeA:undetectable5oajE-4xqeA:undetectable | 5oajD-4xqeA:19.835oajE-4xqeA:19.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aa5 | NIFE-HYDROGENASELARGE SUBUNIT, HOFG (Cupriavidusnecator) |
PF00374(NiFeSe_Hases) | 4 | GLU C 116CYH C 576CYH C 81ARG C 501 | NoneNFU C 701 (-2.2A)NFU C 701 (-2.2A)NFU C 701 (-4.6A) | 1.05A | 5oajD-5aa5C:undetectable5oajE-5aa5C:undetectable | 5oajD-5aa5C:17.185oajE-5aa5C:17.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aza | MALTOSE-BINDINGPERIPLASMICPROTEIN,OLIGOSACCHARYL TRANSFERASE STT3SUBUNIT RELATEDPROTEIN (Escherichiacoli;Pyrococcusfuriosus) |
PF13416(SBP_bac_8) | 4 | GLU A 850PHE A 625TYR A 853ARG A 660 | None | 1.38A | 5oajD-5azaA:undetectable5oajE-5azaA:undetectable | 5oajD-5azaA:14.685oajE-5azaA:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c16 | MYOTUBULARIN-RELATEDPROTEIN 1 (Homo sapiens) |
PF02893(GRAM)PF06602(Myotub-related) | 4 | GLU A 471TRP A 227PHE A 550TYR A 555 | None | 1.34A | 5oajD-5c16A:undetectable5oajE-5c16A:undetectable | 5oajD-5c16A:18.505oajE-5c16A:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ja9 | NANOBODY 6 (Lama glama) |
PF07686(V-set) | 4 | TRP A 108PHE A 48TYR A 38ARG A 36 | NoneEDO A 202 ( 4.3A)NoneEDO A 202 ( 3.9A) | 1.04A | 5oajD-5ja9A:undetectable5oajE-5ja9A:undetectable | 5oajD-5ja9A:19.225oajE-5ja9A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9w | ACETOPHENONECARBOXYLASE ALPHASUBUNITACETOPHENONECARBOXYLASE GAMMASUBUNIT (Aromatoleumaromaticum) |
PF01968(Hydantoinase_A)PF05378(Hydant_A_N) | 4 | GLU B 200TYR B 201PHE b 513ARG b 237 | None | 1.41A | 5oajD-5l9wB:undetectable5oajE-5l9wB:undetectable | 5oajD-5l9wB:16.275oajE-5l9wB:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojr | - (-) |
no annotation | 4 | CYH A 294TYR A 44PHE A 320ARG A 278 | None | 1.50A | 5oajD-5ojrA:undetectable5oajE-5ojrA:undetectable | 5oajD-5ojrA:undetectable5oajE-5ojrA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w21 | KLOTHO (Homo sapiens) |
no annotation | 4 | GLU A 832TYR A 824PHE A 755ARG A 751 | None | 1.21A | 5oajD-5w21A:undetectable5oajE-5w21A:undetectable | 5oajD-5w21A:15.985oajE-5w21A:15.98 |