SIMILAR PATTERNS OF AMINO ACIDS FOR 5O4Y_A_CCSA14

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b5f PROTEIN (CARDOSIN A)

(Cynara
cardunculus) 		PF00026
(Asp) 		4 PHE A 125
LEU A 123
TRP A 190
GLY A  34
 None
 0.96A 5o4yA-1b5fA:
undetectable		 5o4yA-1b5fA:
3.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e3h GUANOSINE
PENTAPHOSPHATE
SYNTHETASE

(Streptomyces
antibioticus) 		PF00013
(KH_1)
PF01138
(RNase_PH)
PF03726
(PNPase) 		4 PHE A 406
ASN A 405
ARG A 423
GLY A 426
 None
 0.90A 5o4yA-1e3hA:
undetectable		 5o4yA-1e3hA:
2.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f8v MATURE CAPSID
PROTEIN BETA

(Pariacoto virus) 		PF01829
(Peptidase_A6) 		4 PHE A 130
LEU A 276
ARG A 118
GLY A 132
 None
 1.11A 5o4yA-1f8vA:
undetectable		 5o4yA-1f8vA:
3.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ibq ASPERGILLOPEPSIN

(Aspergillus
phoenicis) 		PF00026
(Asp) 		4 PHE A 125
LEU A 123
TRP A 190
GLY A  34
 None
None
None
ZN  A1457 (-3.6A)
 0.87A 5o4yA-1ibqA:
undetectable		 5o4yA-1ibqA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ize ASPARTIC PROTEINASE

(Aspergillus
oryzae) 		PF00026
(Asp) 		4 PHE A 126
LEU A 124
TRP A 191
GLY A  35
 None
 0.92A 5o4yA-1izeA:
undetectable		 5o4yA-1izeA:
3.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k5c ENDOPOLYGALACTURONAS
E

(Chondrostereum
purpureum) 		PF00295
(Glyco_hydro_28) 		4 PHE A 280
ASN A 279
TRP A 309
GLY A 331
 None
 1.11A 5o4yA-1k5cA:
undetectable		 5o4yA-1k5cA:
3.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5a AMIDE SYNTHASE

(Vibrio cholerae) 		PF00668
(Condensation) 		4 PHE A 366
ASN A 335
LEU A 337
GLY A 368
 None
 1.11A 5o4yA-1l5aA:
undetectable		 5o4yA-1l5aA:
3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psz PROTEIN (SURFACE
ANTIGEN PSAA)

(Streptococcus
pneumoniae) 		PF01297
(ZnuA) 		4 PHE A 100
ASN A  88
LEU A  92
GLY A  95
 None
 0.90A 5o4yA-1pszA:
undetectable		 5o4yA-1pszA:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qdm PROPHYTEPSIN

(Hordeum vulgare) 		PF00026
(Asp)
PF03489
(SapB_2)
PF05184
(SapB_1) 		4 PHE A 130
LEU A 128
TRP A 197
GLY A  38
 None
 0.79A 5o4yA-1qdmA:
undetectable		 5o4yA-1qdmA:
2.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u4f INWARD RECTIFIER
POTASSIUM CHANNEL 2

(Mus musculus) 		PF01007
(IRK) 		4 ASN A 198
LEU A 321
ARG A 325
GLY A 323
 None
 0.80A 5o4yA-1u4fA:
undetectable		 5o4yA-1u4fA:
3.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uh9 HIZOPUSPEPSIN I

(Rhizopus
microsporus) 		PF00026
(Asp) 		4 PHE A 127
LEU A 125
TRP A 195
GLY A  37
 None
 0.97A 5o4yA-1uh9A:
undetectable		 5o4yA-1uh9A:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v5v AMINOMETHYLTRANSFERA
SE

(Pyrococcus
horikoshii) 		PF01571
(GCV_T)
PF08669
(GCV_T_C) 		4 PHE A  60
LEU A  66
ARG A  61
GLY A  62
 None
 1.01A 5o4yA-1v5vA:
undetectable		 5o4yA-1v5vA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y3t HYPOTHETICAL PROTEIN
YXAG

(Bacillus
subtilis) 		PF07883
(Cupin_2) 		4 PHE A 266
LEU A  50
ARG A  19
GLY A  21
 None
 1.01A 5o4yA-1y3tA:
undetectable		 5o4yA-1y3tA:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gix INWARD RECTIFIER
POTASSIUM CHANNEL 2

(Mus musculus) 		PF01007
(IRK) 		4 ASN A 198
LEU A 321
ARG A 325
GLY A 323
 None
 0.84A 5o4yA-2gixA:
undetectable		 5o4yA-2gixA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lyd DECAPPING PROTEIN 1
PACMAN PROTEIN

(Drosophila
melanogaster;
Drosophila
melanogaster) 		PF06058
(DCP1)
no annotation 		4 PHE A  36
LEU B1338
ARG A 103
GLY A 104
 None
 1.14A 5o4yA-2lydA:
undetectable		 5o4yA-2lydA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbf FORK HEAD DOMAIN
CONTAINING PROTEIN

(Brugia malayi) 		PF00250
(Forkhead) 		4 PHE A 374
ASN A 377
ARG A 384
GLY A 382
 None
 1.13A 5o4yA-2mbfA:
undetectable		 5o4yA-2mbfA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nba PREPILIN-TYPE
CLEAVAGE/METHYLATION
N-TERMINAL DOMAIN
PROTEIN

(Neisseria
subflava) 		PF16732
(ComP_DUS) 		4 PHE A 112
LEU A  65
ARG A 113
GLY A  63
 None
 1.01A 5o4yA-2nbaA:
undetectable		 5o4yA-2nbaA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nef NEGATIVE FACTOR
(F-PROTEIN)

(Human
immunodeficiency
virus 1) 		PF00469
(F-protein) 		4 PHE A 185
LEU A  97
ARG A 184
GLY A  99
 None
 0.87A 5o4yA-2nefA:
undetectable		 5o4yA-2nefA:
5.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ny0 ENVELOPE
GLYCOPROTEIN GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE A 468
LEU A 452
ARG A 469
GLY A 471
 None
 1.10A 5o4yA-2ny0A:
undetectable		 5o4yA-2ny0A:
5.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wed PENICILLOPEPSIN

(Penicillium
janthinellum) 		PF00026
(Asp) 		4 PHE A 126
LEU A 124
TRP A 191
GLY A  35
 None
None
None
PP6  A 327 (-4.0A)
 0.89A 5o4yA-2wedA:
undetectable		 5o4yA-2wedA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xro HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGV

(Pseudomonas
putida) 		PF01614
(IclR)
PF09339
(HTH_IclR) 		4 PHE A  72
LEU A  57
ARG A  73
GLY A  75
 None
 0.95A 5o4yA-2xroA:
undetectable		 5o4yA-2xroA:
3.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zhl GALECTIN-9

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  45
LEU A  38
ARG A  44
GLY A  42
 None
None
NAG  A1491 (-4.6A)
None
 0.75A 5o4yA-2zhlA:
undetectable		 5o4yA-2zhlA:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdl STAPHYLOCOCCAL
NUCLEASE
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00565
(SNase)
PF00567
(TUDOR) 		4 PHE A 582
ASN A 581
LEU A 529
GLY A 584
 None
 1.01A 5o4yA-3bdlA:
undetectable		 5o4yA-3bdlA:
2.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cc1 PUTATIVE
ALPHA-N-ACETYLGALACT
OSAMINIDASE

(Bacillus
halodurans) 		PF16499
(Melibiase_2) 		4 PHE A 169
ASN A 166
ARG A 210
GLY A 209
 None
 0.98A 5o4yA-3cc1A:
undetectable		 5o4yA-3cc1A:
6.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgg SAM-DEPENDENT
METHYLTRANSFERASE

(Corynebacterium
glutamicum) 		PF13649
(Methyltransf_25) 		4 PHE A 119
LEU A 120
ARG A 150
GLY A 151
 None
EDO  A 197 (-4.0A)
None
None
 1.10A 5o4yA-3cggA:
undetectable		 5o4yA-3cggA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cq5 HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Corynebacterium
glutamicum) 		PF00155
(Aminotran_1_2) 		4 ASN A  33
LEU A 331
ARG A 328
GLY A 329
 None
 1.09A 5o4yA-3cq5A:
undetectable		 5o4yA-3cq5A:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emy TRICHODERMA REESEI
ASPARTIC PROTEASE

(Trichoderma
reesei) 		PF00026
(Asp) 		4 PHE A 125
LEU A 123
TRP A 190
GLY A  34
 None
 0.88A 5o4yA-3emyA:
undetectable		 5o4yA-3emyA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fr8 PUTATIVE KETOL-ACID
REDUCTOISOMERASE
(OS05G0573700
PROTEIN)

(Oryza sativa) 		PF01450
(IlvC)
PF07991
(IlvN) 		4 PHE A 504
ASN A 502
ARG A 508
GLY A 509
 None
 0.87A 5o4yA-3fr8A:
undetectable		 5o4yA-3fr8A:
2.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fw0 PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE

(Rattus
norvegicus) 		PF01436
(NHL) 		4 PHE A 581
ASN A 579
ARG A 533
GLY A 534
 None
None
HH3  A   1 (-2.7A)
None
 0.82A 5o4yA-3fw0A:
undetectable		 5o4yA-3fw0A:
9.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hig AMILORIDE-SENSITIVE
AMINE OXIDASE

(Homo sapiens) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 PHE A 310
LEU A 318
ARG A 309
GLY A 320
 None
 1.10A 5o4yA-3higA:
undetectable		 5o4yA-3higA:
2.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ip1 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 PHE A  89
ASN A 154
LEU A  27
GLY A  25
 None
 1.08A 5o4yA-3ip1A:
undetectable		 5o4yA-3ip1A:
5.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j70 ENVELOPE
GLYCOPROTEIN GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE D 468
LEU D 452
ARG D 469
GLY D 471
 None
 1.04A 5o4yA-3j70D:
undetectable		 5o4yA-3j70D:
4.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jwo HIV-1 GP120 ENVELOPE
GLYCOPROTEIN

(Homo sapiens) 		PF00516
(GP120) 		4 PHE A 468
LEU A 452
ARG A 469
GLY A 471
 None
 1.10A 5o4yA-3jwoA:
undetectable		 5o4yA-3jwoA:
4.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kc2 UNCHARACTERIZED
PROTEIN YKR070W

(Saccharomyces
cerevisiae) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 ASN A 186
LEU A 185
ARG A 189
GLY A 183
 None
 1.08A 5o4yA-3kc2A:
undetectable		 5o4yA-3kc2A:
3.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kls EXOTOXIN 1

(Staphylococcus
aureus) 		PF02876
(Stap_Strp_tox_C)
PF09199
(SSL_OB) 		4 PHE X  85
ASN X  71
LEU X  86
GLY X 120
 None
 1.05A 5o4yA-3klsX:
undetectable		 5o4yA-3klsX:
4.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3km5 LYSINE SPECIFIC
CYSTEINE PROTEASE

(Porphyromonas
gingivalis) 		PF07675
(Cleaved_Adhesin) 		4 PHE A1281
LEU A1283
ARG A1280
GLY A1214
 None
 0.99A 5o4yA-3km5A:
undetectable		 5o4yA-3km5A:
6.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pa8 TOXIN B

(Clostridioides
difficile) 		PF11713
(Peptidase_C80) 		4 PHE A 107
ASN A 151
LEU A 153
GLY A 109
 None
IHP  A 257 ( 4.0A)
621  A 300 ( 4.8A)
621  A 300 (-4.8A)
 1.15A 5o4yA-3pa8A:
undetectable		 5o4yA-3pa8A:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pnz PHOSPHOTRIESTERASE
FAMILY PROTEIN

(Listeria
monocytogenes) 		PF02126
(PTE) 		4 ASN A  96
LEU A 100
TRP A 101
GLY A 103
 PO4  A 335 ( 2.8A)
None
None
None
 0.95A 5o4yA-3pnzA:
undetectable		 5o4yA-3pnzA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r67 PUTATIVE GLYCOSIDASE

(Bacteroides
thetaiotaomicron) 		PF04041
(Glyco_hydro_130) 		4 PHE A 185
ASN A 240
ARG A 192
GLY A 191
 None
 1.08A 5o4yA-3r67A:
undetectable		 5o4yA-3r67A:
4.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgq HIV-1 YU2 GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE A 468
LEU A 452
ARG A 469
GLY A 471
 None
 1.15A 5o4yA-3tgqA:
undetectable		 5o4yA-3tgqA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wv6 GALECTIN-9

(Homo sapiens) 		PF00337
(Gal-bind_lectin) 		4 PHE A  45
LEU A  38
ARG A  44
GLY A  42
 None
None
GAL  A 402 ( 4.9A)
None
 0.75A 5o4yA-3wv6A:
undetectable		 5o4yA-3wv6A:
4.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4azw WBDD

(Escherichia
coli) 		PF00069
(Pkinase)
PF13847
(Methyltransf_31) 		4 PHE A 105
ASN A  87
ARG A 106
GLY A 108
 None
SAM  A1451 (-4.0A)
None
None
 1.10A 5o4yA-4azwA:
undetectable		 5o4yA-4azwA:
2.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvu BETA-MANNOSIDASE

(Trichoderma
harzianum) 		PF00703
(Glyco_hydro_2) 		4 PHE A 898
TRP A 726
ARG A 406
GLY A 724
 None
 1.07A 5o4yA-4cvuA:
undetectable		 5o4yA-4cvuA:
1.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cxk ARYLSULFATASE

(Pseudomonas
aeruginosa) 		PF00884
(Sulfatase) 		4 PHE A 202
ASN A   6
ARG A 102
GLY A 105
 None
 1.15A 5o4yA-4cxkA:
undetectable		 5o4yA-4cxkA:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdu PUTATIVE MULTIPLE
INOSITOL
POLYPHOSPHATE
HISTIDINE
PHOSPHATASE 1

(Bacteroides
thetaiotaomicron) 		PF00328
(His_Phos_2) 		4 PHE A  63
LEU A 114
ARG A 149
GLY A  60
 None
None
IHS  A 501 (-3.5A)
None
 1.11A 5o4yA-4fduA:
undetectable		 5o4yA-4fduA:
2.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0m SERINE/THREONINE-PRO
TEIN KINASE
BRI1-LIKE 1

(Arabidopsis
thaliana) 		PF08263
(LRRNT_2)
PF13516
(LRR_6)
PF13855
(LRR_8) 		4 ASN A 744
LEU A 747
ARG A 753
GLY A 749
 None
 1.15A 5o4yA-4j0mA:
undetectable		 5o4yA-4j0mA:
1.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jm2 GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE E 468
LEU E 452
ARG E 469
GLY E 471
 None
None
NAG  E 523 (-3.0A)
None
 1.09A 5o4yA-4jm2E:
undetectable		 5o4yA-4jm2E:
5.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0i GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A,
MITOCHONDRIAL
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT B,
MITOCHONDRIAL

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF01425
(Amidase)
PF02934
(GatB_N) 		4 PHE A 347
ASN A 350
ARG B 299
GLY A 338
 None
 0.75A 5o4yA-4n0iA:
undetectable		 5o4yA-4n0iA:
3.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0l PREDICTED COMPONENT
OF A
THERMOPHILE-SPECIFIC
DNA REPAIR SYSTEM,
CONTAINS A RAMP
DOMAIN

(Methanopyrus
kandleri) 		PF03787
(RAMPs) 		4 PHE A 270
LEU A  10
ARG A 271
GLY A  12
 None
 0.97A 5o4yA-4n0lA:
undetectable		 5o4yA-4n0lA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnp LIPOPROTEIN

(Staphylococcus
aureus) 		PF01297
(ZnuA) 		4 PHE A  99
ASN A  88
LEU A  92
GLY A  95
 None
 1.06A 5o4yA-4nnpA:
undetectable		 5o4yA-4nnpA:
5.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oxr MANGANESE ABC
TRANSPORTER,
PERIPLASMIC-BINDING
PROTEIN SITA

(Staphylococcus
pseudintermedius) 		PF01297
(ZnuA) 		4 PHE A  96
ASN A  85
LEU A  89
GLY A  92
 None
 1.01A 5o4yA-4oxrA:
undetectable		 5o4yA-4oxrA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pir 5-HYDROXYTRYPTAMINE
RECEPTOR 3A

(Mus musculus) 		PF02931
(Neur_chan_LBD)
PF02932
(Neur_chan_memb) 		4 PHE A 142
ASN A 141
LEU A 282
GLY A 284
 None
 1.04A 5o4yA-4pirA:
undetectable		 5o4yA-4pirA:
2.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0j UNCHARACTERIZED
PROTEIN

(Streptococcus
mutans) 		PF09704
(Cas_Cas5d) 		4 PHE A 145
LEU A 147
ARG A  17
GLY A  15
 None
 1.14A 5o4yA-4r0jA:
undetectable		 5o4yA-4r0jA:
3.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r2g SURFACE PROTEIN
GP160

(Human
immunodeficiency
virus 1) 		no annotation 4 PHE E 468
LEU E 452
ARG E 469
GLY E 471
 None
 1.02A 5o4yA-4r2gE:
undetectable		 5o4yA-4r2gE:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r4h HIV-1 ENV GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE A 468
LEU A 451
ARG A 469
GLY A 471
 None
None
NAG  A 606 ( 4.7A)
None
 1.06A 5o4yA-4r4hA:
undetectable		 5o4yA-4r4hA:
2.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rkk LAFORIN

(Homo sapiens) 		PF00686
(CBM_20)
PF00782
(DSPc) 		4 PHE A   3
ASN A 116
ARG A   2
GLY A 120
 None
 1.14A 5o4yA-4rkkA:
undetectable		 5o4yA-4rkkA:
3.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rx4 HIV-1 CLADE A
Q842.D12 GP120

(Human
immunodeficiency
virus 1) 		no annotation 4 PHE G 468
LEU G 452
ARG G 469
GLY G 471
 None
None
EDO  G 513 ( 4.8A)
None
 1.12A 5o4yA-4rx4G:
undetectable		 5o4yA-4rx4G:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s28 PHOSPHOMETHYLPYRIMID
INE SYNTHASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF01964
(ThiC_Rad_SAM) 		4 PHE A 448
LEU A 481
ARG A 219
GLY A 218
 None
 0.94A 5o4yA-4s28A:
undetectable		 5o4yA-4s28A:
2.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uw2 CSM1

(Thermococcus
onnurineus) 		PF01966
(HD) 		4 PHE A 352
LEU A 103
ARG A 345
GLY A 106
 None
 1.11A 5o4yA-4uw2A:
undetectable		 5o4yA-4uw2A:
2.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w9u ACYL-COA
DEHYDROGENASE

(Brucella
abortus) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 PHE A 269
LEU A 295
TRP A 268
ARG A 270
 EDO  A 402 ( 3.9A)
None
None
None
 1.10A 5o4yA-4w9uA:
undetectable		 5o4yA-4w9uA:
3.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wmy INTELECTIN-1

(Homo sapiens) 		no annotation 4 ASN A 116
TRP A 117
ARG A 239
GLY A 269
 None
 1.12A 5o4yA-4wmyA:
undetectable		 5o4yA-4wmyA:
4.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ye4 HT593.1 GP120

(Human
immunodeficiency
virus) 		PF00516
(GP120) 		4 PHE G 470
LEU G 452
ARG G 471
GLY G 473
 None
 1.02A 5o4yA-4ye4G:
undetectable		 5o4yA-4ye4G:
7.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7x HIV-1 YU2 GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE A 468
LEU A 452
ARG A 469
GLY A 471
 None
 1.12A 5o4yA-5a7xA:
undetectable		 5o4yA-5a7xA:
6.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5axk TRNA(HIS)-5'-GUANYLY
LTRANSFERASE (THG1)
LIKE PROTEIN

(Methanosarcina
acetivorans) 		PF04446
(Thg1)
PF14413
(Thg1C) 		4 PHE A 138
ASN A 137
ARG A 189
GLY A 190
 None
 1.00A 5o4yA-5axkA:
undetectable		 5o4yA-5axkA:
5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5azb PROLIPOPROTEIN
DIACYLGLYCERYL
TRANSFERASE

(Escherichia
coli) 		PF01790
(LGT) 		4 PHE A 147
ASN A 146
LEU A 152
GLY A 154
 None
 1.12A 5o4yA-5azbA:
undetectable		 5o4yA-5azbA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b26 PROTEIN SEL-1
HOMOLOG 1

(Mus musculus) 		PF08238
(Sel1) 		4 ASN A 462
LEU A 465
ARG A 457
GLY A 450
 None
 1.04A 5o4yA-5b26A:
undetectable		 5o4yA-5b26A:
4.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3p NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 5

(Thermus
thermophilus) 		PF00329
(Complex1_30kDa) 		4 PHE A  48
ASN A  47
ARG A  87
GLY A  85
 None
None
CA  A 202 ( 4.5A)
None
 0.73A 5o4yA-5b3pA:
undetectable		 5o4yA-5b3pA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cad SM80.1 VICILIN

(Solanum
melongena) 		PF00190
(Cupin_1) 		4 LEU A 349
TRP A 356
ARG A 357
GLY A 351
 None
 1.10A 5o4yA-5cadA:
undetectable		 5o4yA-5cadA:
3.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5che GLUTAMYL-TRNA
REDUCTASE-BINDING
PROTEIN,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF10615
(DUF2470) 		4 PHE C  93
LEU C  77
ARG C  92
GLY C  90
 None
 1.13A 5o4yA-5cheC:
undetectable		 5o4yA-5cheC:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm6 50S RIBOSOMAL
PROTEIN L6

(Deinococcus
radiodurans) 		PF00347
(Ribosomal_L6) 		4 ASN E  38
LEU E  64
ARG E  69
GLY E  66
 None
None
None
A  X2748 ( 3.4A)
 0.93A 5o4yA-5dm6E:
undetectable		 5o4yA-5dm6E:
3.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do7 ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
8

(Homo sapiens) 		PF00005
(ABC_tran)
PF01061
(ABC2_membrane) 		4 PHE B 453
LEU B 452
ARG B 597
GLY B 602
 None
 1.13A 5o4yA-5do7B:
undetectable		 5o4yA-5do7B:
2.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fur TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 2

(Homo sapiens) 		no annotation 4 PHE I 647
TRP I 627
ARG I 654
GLY I 573
 None
 1.04A 5o4yA-5furI:
undetectable		 5o4yA-5furI:
1.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fur TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 6

(Homo sapiens) 		PF07571
(TAF6_C) 		4 ASN J 275
LEU J 278
ARG J 268
GLY J 266
 None
 1.06A 5o4yA-5furJ:
undetectable		 5o4yA-5furJ:
2.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fuu HIV-1 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE A 468
LEU A 452
ARG A 469
GLY A 471
 None
None
NAG  A1362 ( 4.4A)
None
 1.09A 5o4yA-5fuuA:
undetectable		 5o4yA-5fuuA:
3.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hct ENDOTHIAPEPSIN

(Cryphonectria
parasitica) 		PF00026
(Asp) 		4 PHE A 130
LEU A 128
TRP A 195
GLY A  37
 None
None
None
61P  A 406 ( 4.0A)
 0.93A 5o4yA-5hctA:
undetectable		 5o4yA-5hctA:
2.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hdi CYTOCHROME P450 144

(Mycobacterium
tuberculosis) 		PF00067
(p450) 		4 ASN A 304
LEU A 307
ARG A 397
GLY A 309
 None
 1.14A 5o4yA-5hdiA:
undetectable		 5o4yA-5hdiA:
2.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hy7 PUTATIVE PRE-MRNA
SPLICING PROTEIN

(Chaetomium
thermophilum) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 PHE A  66
LEU A1151
ARG A1154
GLY A1153
 None
 1.00A 5o4yA-5hy7A:
undetectable		 5o4yA-5hy7A:
1.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4k MANGANESE-BINDING
LIPOPROTEIN MNTA

(Listeria
monocytogenes) 		PF01297
(ZnuA) 		4 PHE A  99
ASN A  88
LEU A  92
GLY A  95
 None
 0.99A 5o4yA-5i4kA:
undetectable		 5o4yA-5i4kA:
4.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j11 THYMIC STROMAL
LYMPHOPOIETIN

(Homo sapiens) 		PF15216
(TSLP) 		4 LEU A 144
TRP A 148
ARG A 150
GLY A 146
 None
 1.02A 5o4yA-5j11A:
undetectable		 5o4yA-5j11A:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j12 THYMIC STROMAL
LYMPHOPOIETIN

(Homo sapiens) 		PF15216
(TSLP) 		4 LEU A 144
TRP A 148
ARG A 150
GLY A 146
 None
 1.01A 5o4yA-5j12A:
undetectable		 5o4yA-5j12A:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kum ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 12

(Gallus gallus) 		PF01007
(IRK) 		4 ASN A 199
LEU A 322
ARG A 326
GLY A 324
 None
 0.85A 5o4yA-5kumA:
undetectable		 5o4yA-5kumA:
2.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nfg PROCARDOSIN-B,PROCAR
DOSIN-B

(Cynara
cardunculus) 		no annotation 4 PHE A 174
LEU A 172
TRP A 241
GLY A  82
 None
 0.91A 5o4yA-5nfgA:
undetectable		 5o4yA-5nfgA:
3.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nvm EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E
TYPE 2
GRB10-INTERACTING
GYF PROTEIN 2

(Homo sapiens;
Homo sapiens) 		PF01652
(IF4E)
no annotation 		4 PHE A  94
LEU B  51
TRP A  95
ARG A  96
 None
None
None
PO4  B 101 (-2.9A)
 1.05A 5o4yA-5nvmA:
undetectable		 5o4yA-5nvmA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5p60 ENDOTHIAPEPSIN

(Cryphonectria
parasitica) 		PF00026
(Asp) 		4 PHE A 130
LEU A 128
TRP A 195
GLY A  37
 None
 0.94A 5o4yA-5p60A:
undetectable		 5o4yA-5p60A:
3.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tkz MEC-8 PROTEIN

(Caenorhabditis
elegans) 		PF00076
(RRM_1) 		4 PHE A  98
LEU A  93
ARG A  97
GLY A  95
 None
 1.12A 5o4yA-5tkzA:
undetectable		 5o4yA-5tkzA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um8 GLYCOPROTEIN GP120

(Human
immunodeficiency
virus 1) 		PF00516
(GP120) 		4 PHE G 468
LEU G 452
ARG G 469
GLY G 471
 None
 0.80A 5o4yA-5um8G:
undetectable		 5o4yA-5um8G:
1.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf5 SM80.1 VICILIN

(Solanum
melongena) 		no annotation 4 LEU A 354
TRP A 361
ARG A 362
GLY A 356
 None
 1.00A 5o4yA-5vf5A:
undetectable		 5o4yA-5vf5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ww1 PULULLANASE

(Paenibacillus
barengoltzii) 		no annotation 4 ASN A 341
LEU A 325
ARG A 331
GLY A 322
 None
 1.13A 5o4yA-5ww1A:
undetectable		 5o4yA-5ww1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjn CYTOCHROME P450

(Corynebacterium
glutamicum) 		PF00067
(p450) 		4 PHE A 416
LEU A 414
ARG A 411
GLY A 200
 88L  A 501 ( 4.7A)
None
None
None
 1.12A 5o4yA-5xjnA:
undetectable		 5o4yA-5xjnA:
4.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9d ACYL-COENZYME A
OXIDASE 1

(Yarrowia
lipolytica) 		no annotation 4 ASN A 113
LEU A 114
ARG A 107
GLY A 188
 None
None
None
FAD  A 701 (-3.9A)
 1.07A 5o4yA-5y9dA:
undetectable		 5o4yA-5y9dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yll BETA-1,4-MANNANASE

(Amphibacillus
xylanus) 		no annotation 4 PHE B   7
LEU B  27
TRP B 275
GLY B  10
 None
 1.08A 5o4yA-5yllB:
undetectable		 5o4yA-5yllB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zc2 -

(-) 		no annotation 4 LEU B  61
TRP B  62
ARG B 130
GLY B 144
 None
 0.93A 5o4yA-5zc2B:
undetectable		 5o4yA-5zc2B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zji CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC

(Zea mays) 		no annotation 4 PHE 4 190
ASN 4 191
ARG 4 157
GLY 4 184
 CHL  4 608 (-4.1A)
LUT  4 619 (-3.1A)
CLA  4 609 ( 2.3A)
CHL  4 608 (-3.8A)
 1.06A 5o4yA-5zji4:
undetectable		 5o4yA-5zji4:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus 1) 		no annotation 4 PHE G 468
LEU G 452
ARG G 469
GLY G 471
 None
 1.15A 5o4yA-6b0nG:
undetectable		 5o4yA-6b0nG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cc2 CELL DIVISION
CONTROL PROTEIN 45
CDC45 PUTATIVE

(Entamoeba
histolytica) 		no annotation 4 PHE A  46
LEU A  52
ARG A  16
GLY A  19
 None
 1.11A 5o4yA-6cc2A:
undetectable		 5o4yA-6cc2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccu GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG

(Homo sapiens) 		no annotation 4 PHE A 128
LEU A 284
ARG A 129
GLY A 130
 None
 1.05A 5o4yA-6ccuA:
undetectable		 5o4yA-6ccuA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cd8 GLUCOSE-INDUCED
DEGRADATION PROTEIN
4 HOMOLOG

(Homo sapiens) 		no annotation 4 PHE A 128
LEU A 284
ARG A 129
GLY A 130
 None
 1.03A 5o4yA-6cd8A:
undetectable		 5o4yA-6cd8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6en4 SPLICING FACTOR 3B
SUBUNIT 3

(Homo sapiens) 		no annotation 4 PHE A  59
LEU A1137
ARG A1140
GLY A1139
 None
 0.98A 5o4yA-6en4A:
undetectable		 5o4yA-6en4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exs PEPTIDE ABC
TRANSPORTER PERMEASE

(Staphylococcus
hominis) 		no annotation 4 PHE A 207
TRP A 203
ARG A  24
GLY A  27
 OLC  A 508 ( 4.8A)
None
None
None
 0.91A 5o4yA-6exsA:
undetectable		 5o4yA-6exsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fc0 EUKARYOTIC
TRANSLATION
INITIATION FACTOR
4E-LIKE PROTEIN
EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4G

(Chaetomium
thermophilum;
Chaetomium
thermophilum) 		no annotation
no annotation 		4 PHE B1004
ASN B 984
LEU B 987
GLY A 150
 None
 1.05A 5o4yA-6fc0B:
undetectable		 5o4yA-6fc0B:
undetectable