SIMILAR PATTERNS OF AMINO ACIDS FOR 5NZY_A_CE3A1103_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dgf | CATALASE (Homo sapiens) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 358ASP A 348VAL A 146GLY A 147 | HEM A3000 (-3.9A)NoneHEM A3000 (-4.7A)HEM A3000 (-3.8A) | 0.96A | 5nzyA-1dgfA:undetectable | 5nzyA-1dgfA:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ee8 | MUTM (FPG) PROTEIN (Thermusthermophilus) |
PF01149(Fapy_DNA_glyco)PF06827(zf-FPG_IleRS)PF06831(H2TH) | 4 | THR A 260GLN A 262ASP A 165GLY A 235 | None | 0.98A | 5nzyA-1ee8A:undetectable | 5nzyA-1ee8A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gvh | FLAVOHEMOPROTEIN (Escherichiacoli) |
PF00042(Globin)PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 4 | TYR A 217GLN A 187VAL A 180GLY A 147 | None | 0.82A | 5nzyA-1gvhA:undetectable | 5nzyA-1gvhA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7k | CATALASE (Proteusmirabilis) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 337ASP A 327VAL A 125GLY A 126 | HEM A 600 (-3.8A)NoneHEM A 600 (-4.9A)HEM A 600 (-3.8A) | 0.98A | 5nzyA-1h7kA:undetectable | 5nzyA-1h7kA:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ktn | 2-DEOXYRIBOSE-5-PHOSPHATE ALDOLASE (Escherichiacoli) |
PF01791(DeoC) | 4 | PRO A 179TYR A 215VAL A 206GLY A 205 | None | 0.99A | 5nzyA-1ktnA:2.6 | 5nzyA-1ktnA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p33 | PTERIDINE REDUCTASE1 (Leishmaniatarentolae) |
PF13561(adh_short_C2) | 4 | THR A 5PRO A 7TYR A 31VAL A 105 | None | 1.00A | 5nzyA-1p33A:undetectable | 5nzyA-1p33A:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rc9 | CYSTEINE-RICHSECRETORY PROTEIN (Trimeresurusstejnegeri) |
PF00188(CAP)PF08562(Crisp) | 4 | THR A 157PRO A 160TYR A 161VAL A 29 | None | 0.99A | 5nzyA-1rc9A:undetectable | 5nzyA-1rc9A:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s4e | GALACTOKINASE (Pyrococcusfuriosus) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | TYR A 72ASP A 151VAL A 143GLY A 144 | ADP A 400 (-3.6A)GLA A 500 (-3.0A)NoneNone | 1.00A | 5nzyA-1s4eA:undetectable | 5nzyA-1s4eA:23.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1si8 | CATALASE (Enterococcusfaecalis) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 337ASP A 327VAL A 125GLY A 126 | HEM A 501 (-3.8A)NoneHEM A 501 (-4.8A)HEM A 501 (-3.8A) | 0.96A | 5nzyA-1si8A:undetectable | 5nzyA-1si8A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sy7 | CATALASE 1 (Neurosporacrassa) |
PF00199(Catalase)PF01965(DJ-1_PfpI)PF06628(Catalase-rel) | 4 | TYR A 379ASP A 369VAL A 163GLY A 164 | HDD A1880 ( 4.0A)NoneHDD A1880 ( 4.8A)HDD A1880 ( 3.9A) | 0.88A | 5nzyA-1sy7A:undetectable | 5nzyA-1sy7A:17.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uli | BIPHENYL DIOXYGENASELARGE SUBUNITBIPHENYL DIOXYGENASESMALL SUBUNIT (Rhodococcusjostii) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A)PF00866(Ring_hydroxyl_B) | 4 | GLN B 175ASP B 145GLY A 371ARG B 91 | None | 0.97A | 5nzyA-1uliB:undetectable | 5nzyA-1uliB:18.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uqw | PUTATIVE BINDINGPROTEIN YLIB (Escherichiacoli) |
PF00496(SBP_bac_5) | 4 | THR A 17ASP A 174VAL A 11GLY A 12 | None | 1.02A | 5nzyA-1uqwA:undetectable | 5nzyA-1uqwA:21.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v8b | ADENOSYLHOMOCYSTEINASE (Plasmodiumfalciparum) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 320ASP A 234VAL A 205GLY A 204 | NAD A 501 (-3.8A)ADN A 502 (-2.8A)NoneNone | 0.83A | 5nzyA-1v8bA:2.3 | 5nzyA-1v8bA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wk9 | VALYL-TRNASYNTHETASE (Thermusthermophilus) |
PF00133(tRNA-synt_1) | 4 | THR A 219PRO A 217TYR A 198GLY A 195 | TSB A 999 (-3.8A)NoneNoneNone | 0.77A | 5nzyA-1wk9A:undetectable | 5nzyA-1wk9A:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xcr | HYPOTHETICAL PROTEINPTD012 (Homo sapiens) |
PF08925(DUF1907) | 4 | PRO A 11TYR A 196VAL A 19GLY A 18 | None | 0.95A | 5nzyA-1xcrA:undetectable | 5nzyA-1xcrA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yv9 | HYDROLASE, HALOACIDDEHALOGENASE FAMILY (Enterococcusfaecalis) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | THR A 176PRO A 178TYR A 180GLY A 121 | None | 0.90A | 5nzyA-1yv9A:3.1 | 5nzyA-1yv9A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zbr | CONSERVEDHYPOTHETICAL PROTEIN (Porphyromonasgingivalis) |
PF04371(PAD_porph) | 4 | PRO A 290TYR A 292VAL A 322GLY A 326 | None | 0.73A | 5nzyA-1zbrA:undetectable | 5nzyA-1zbrA:24.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2be1 | SERINE/THREONINE-PROTEINKINASE/ENDORIBONUCLEASE IRE1 (Saccharomycescerevisiae) |
no annotation | 4 | THR A 283GLN A 152VAL A 356GLY A 357 | None | 0.93A | 5nzyA-2be1A:undetectable | 5nzyA-2be1A:20.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c3d | 2-OXOPROPYL-COMREDUCTASE (Xanthobacterautotrophicus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | THR A 446TYR A 260VAL A 470GLY A 471 | None | 0.82A | 5nzyA-2c3dA:undetectable | 5nzyA-2c3dA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dej | PROBABLEGALACTOKINASE (Pyrococcushorikoshii) |
PF00288(GHMP_kinases_N)PF08544(GHMP_kinases_C)PF10509(GalKase_gal_bdg) | 4 | TYR A 70ASP A 149VAL A 141GLY A 142 | APW A 402 (-3.8A)GLA A 401 (-3.1A)NoneNone | 1.03A | 5nzyA-2dejA:undetectable | 5nzyA-2dejA:24.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dg2 | APOLIPOPROTEIN A-IBINDING PROTEIN (Mus musculus) |
PF03853(YjeF_N) | 4 | THR A 222PRO A 205ASP A 188GLY A 192 | None | 0.89A | 5nzyA-2dg2A:2.8 | 5nzyA-2dg2A:18.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iqf | CATALASE (Helicobacterpylori) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 339ASP A 329VAL A 127GLY A 128 | HEM A 550 (-3.8A)NoneHEM A 550 (-4.8A)HEM A 550 (-3.9A) | 0.97A | 5nzyA-2iqfA:undetectable | 5nzyA-2iqfA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j2m | CATALASE (Exiguobacteriumoxidotolerans) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 339ASP A 329VAL A 127GLY A 128 | HEM A 501 (-3.8A)NoneHEM A 501 ( 4.8A)HEM A 501 (-3.7A) | 0.93A | 5nzyA-2j2mA:undetectable | 5nzyA-2j2mA:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jer | AGMATINE DEIMINASE (Enterococcusfaecalis) |
PF04371(PAD_porph) | 4 | PRO A 317TYR A 319VAL A 349GLY A 353 | NoneNoneNoneAGT A 357 ( 3.8A) | 0.86A | 5nzyA-2jerA:undetectable | 5nzyA-2jerA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdr | UNCHARACTERIZEDPROTEIN (Nostocpunctiforme) |
PF14499(DUF4437) | 4 | TYR A 133ASP A 111VAL A 218GLY A 217 | None | 0.90A | 5nzyA-2qdrA:undetectable | 5nzyA-2qdrA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qhx | PTERIDINE REDUCTASE1 (Leishmaniamajor) |
PF00106(adh_short)PF13561(adh_short_C2) | 4 | THR A 5PRO A 7TYR A 31VAL A 105 | None | 0.96A | 5nzyA-2qhxA:undetectable | 5nzyA-2qhxA:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wk2 | CHITINASE A (Serratiamarcescens) |
PF00704(Glyco_hydro_18)PF08329(ChitinaseA_N) | 4 | THR A 494PRO A 502ASP A 547GLY A 445 | None | 0.97A | 5nzyA-2wk2A:1.4 | 5nzyA-2wk2A:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x1f | MRNA3'-END-PROCESSINGPROTEIN RNA15 (Saccharomycescerevisiae) |
PF00076(RRM_1) | 4 | PRO A 16TYR A 93ASP A 68VAL A 76 | None | 1.04A | 5nzyA-2x1fA:undetectable | 5nzyA-2x1fA:14.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afl | OLIGO ALGINATE LYASE (Agrobacteriumfabrum) |
PF07940(Hepar_II_III)PF16332(DUF4962) | 4 | PRO A 185GLN A 200VAL A 259GLY A 256 | None | 1.00A | 5nzyA-3aflA:undetectable | 5nzyA-3aflA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ahy | BETA-GLUCOSIDASE (Trichodermareesei) |
PF00232(Glyco_hydro_1) | 4 | ASP A 60VAL A 435GLY A 434ARG A 389 | None | 1.04A | 5nzyA-3ahyA:1.2 | 5nzyA-3ahyA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 338ASP A 252VAL A 223GLY A 222 | NAD A 550 (-4.1A)ADN A 500 (-2.7A)NoneNone | 0.91A | 5nzyA-3ce6A:2.8 | 5nzyA-3ce6A:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3x | BIPA (Vibrioparahaemolyticus) |
PF00679(EFG_C) | 4 | THR A 282PRO A 284VAL A 240GLY A 239 | None | 0.97A | 5nzyA-3e3xA:undetectable | 5nzyA-3e3xA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e4w | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycobacteriumavium) |
PF00199(Catalase) | 4 | TYR A 34ASP A 208GLY A 31ARG A 63 | NoneNoneNoneHEM A 501 (-3.6A) | 0.95A | 5nzyA-3e4wA:undetectable | 5nzyA-3e4wA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eje | ACYL CARRIER PROTEIN (Escherichiacoli) |
PF00550(PP-binding) | 4 | THR A 84ASP A 55VAL A 37GLY A 32 | None | 0.96A | 5nzyA-3ejeA:undetectable | 5nzyA-3ejeA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gzy | BIPHENYL DIOXYGENASESUBUNIT ALPHABIPHENYL DIOXYGENASESUBUNIT BETA (Comamonastestosteroni) |
PF00355(Rieske)PF00848(Ring_hydroxyl_A)PF00866(Ring_hydroxyl_B) | 4 | GLN B 174ASP B 144GLY A 379ARG B 90 | None | 1.04A | 5nzyA-3gzyB:undetectable | 5nzyA-3gzyB:17.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h8f | CYTOSOLAMINOPEPTIDASE (Pseudomonasputida) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | THR A 158TYR A 127ASP A 114GLY A 165 | None | 0.90A | 5nzyA-3h8fA:2.6 | 5nzyA-3h8fA:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ho8 | PYRUVATE CARBOXYLASE (Staphylococcusaureus) |
PF00289(Biotin_carb_N)PF00682(HMGL-like)PF02436(PYC_OADA)PF02785(Biotin_carb_C)PF02786(CPSase_L_D2) | 4 | TYR A 118GLN A 375GLY A 46ARG A 45 | None | 1.04A | 5nzyA-3ho8A:undetectable | 5nzyA-3ho8A:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i6d | PROTOPORPHYRINOGENOXIDASE (Bacillussubtilis) |
PF01593(Amino_oxidase) | 4 | TYR A 177GLN A 192VAL A 448GLY A 449 | NoneNoneFAD A 600 (-4.4A)FAD A 600 ( 3.7A) | 0.85A | 5nzyA-3i6dA:undetectable | 5nzyA-3i6dA:22.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb5 | MAJOR CAPSID PROTEIN (Propionibacteriumvirus PA6) |
no annotation | 4 | THR A 146ASP A 121VAL A 178GLY A 177 | None | 1.04A | 5nzyA-3jb5A:undetectable | 5nzyA-3jb5A:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kzv | UNCHARACTERIZEDOXIDOREDUCTASEYIR035C (Saccharomycescerevisiae) |
PF00106(adh_short) | 4 | THR A 128GLN A 170VAL A 118GLY A 119 | NoneGOL A 256 (-3.8A)NoneNone | 1.04A | 5nzyA-3kzvA:2.2 | 5nzyA-3kzvA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lp8 | PHOSPHORIBOSYLAMINE-GLYCINE LIGASE (Ehrlichiachaffeensis) |
PF01071(GARS_A)PF02843(GARS_C)PF02844(GARS_N) | 4 | THR A 225TYR A 342GLN A 149GLY A 366 | NoneNoneUNX A 426 ( 4.3A)None | 1.01A | 5nzyA-3lp8A:undetectable | 5nzyA-3lp8A:22.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3max | HISTONE DEACETYLASE2 (Homo sapiens) |
PF00850(Hist_deacetyl) | 4 | TYR A 157ASP A 109VAL A 101GLY A 102 | None | 0.73A | 5nzyA-3maxA:1.6 | 5nzyA-3maxA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 312ASP A 226VAL A 197GLY A 196 | NAD A 550 (-4.0A)ADN A 500 ( 2.6A)NoneNone | 0.90A | 5nzyA-3n58A:2.5 | 5nzyA-3n58A:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nr8 | PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE5-PHOSPHATASE 2 (Homo sapiens) |
no annotation | 4 | THR B 430ASP B 478VAL B 546GLY B 545 | None | 0.80A | 5nzyA-3nr8B:undetectable | 5nzyA-3nr8B:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0h | GLUTATHIONEREDUCTASE (Bartonellahenselae) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 4 | THR A 333PRO A 335TYR A 337VAL A 315 | None | 0.77A | 5nzyA-3o0hA:undetectable | 5nzyA-3o0hA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ozv | FLAVOHEMOGLOBIN (Cupriavidusnecator) |
no annotation | 4 | TYR B 219GLN B 189VAL B 182GLY B 149 | None | 0.82A | 5nzyA-3ozvB:undetectable | 5nzyA-3ozvB:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pih | UVRABC SYSTEMPROTEIN A (Thermotogamaritima) |
PF00005(ABC_tran) | 4 | THR A 836GLN A 812GLY A 468ARG A 472 | None | 0.86A | 5nzyA-3pihA:undetectable | 5nzyA-3pihA:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sz3 | TRYPTOPHANYL-TRNASYNTHETASE (Vibrio cholerae) |
PF00579(tRNA-synt_1b) | 4 | TYR A 39ASP A 34VAL A 72GLY A 71 | None | 0.73A | 5nzyA-3sz3A:undetectable | 5nzyA-3sz3A:19.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tt2 | GCN5-RELATEDN-ACETYLTRANSFERASE (Sphaerobacterthermophilus) |
PF00583(Acetyltransf_1) | 4 | PRO A 293TYR A 296VAL A 249GLY A 250 | None | 0.84A | 5nzyA-3tt2A:undetectable | 5nzyA-3tt2A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3upn | PENICILLIN-BINDINGPROTEIN A (Mycobacteriumtuberculosis) |
PF00905(Transpeptidase) | 4 | THR A 314PRO A 365GLY A 306ARG A 388 | None | 0.98A | 5nzyA-3upnA:undetectable | 5nzyA-3upnA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uug | MULTIPLESUGAR-BINDINGPERIPLASMIC RECEPTORCHVE (Agrobacteriumfabrum) |
PF13407(Peripla_BP_4) | 4 | THR A 310GLN A 256VAL A 111GLY A 112 | None | 1.02A | 5nzyA-3uugA:undetectable | 5nzyA-3uugA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uve | CARVEOLDEHYDROGENASE((+)-TRANS-CARVEOLDEHYDROGENASE) (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | THR A 171ASP A 130VAL A 181GLY A 180 | None | 0.84A | 5nzyA-3uveA:undetectable | 5nzyA-3uveA:21.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcr | PUTATIVE KDPG(2-KETO-3-DEOXY-6-PHOSPHOGLUCONATE)ALDOLASE (Oleispiraantarctica) |
PF01081(Aldolase) | 4 | THR A 47ASP A 82VAL A 66GLY A 67 | None | 1.04A | 5nzyA-3vcrA:undetectable | 5nzyA-3vcrA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vi3 | INTEGRIN ALPHA-5 (Homo sapiens) |
PF01839(FG-GAP)PF08441(Integrin_alpha2) | 4 | TYR A 325GLN A 280ASP A 311GLY A 352 | None | 0.88A | 5nzyA-3vi3A:undetectable | 5nzyA-3vi3A:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvo | CRISPR-ASSOCIATEDPROTEIN, CSE1 FAMILY (Thermobifidafusca) |
PF09481(CRISPR_Cse1) | 4 | PRO A 290GLN A 308VAL A 193GLY A 192 | None | 0.81A | 5nzyA-3wvoA:undetectable | 5nzyA-3wvoA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxf | UNCHARACTERIZEDPROTEIN (Danio rerio) |
PF00443(UCH) | 4 | THR A 724PRO A 766VAL A 842GLY A 843 | None | 1.02A | 5nzyA-3wxfA:undetectable | 5nzyA-3wxfA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zth | STU0660 (Streptococcusthermophilus) |
PF16813(Cas_St_Csn2) | 4 | THR A 285PRO A 284TYR A 278VAL A 316 | None | 1.02A | 5nzyA-3zthA:undetectable | 5nzyA-3zthA:24.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zzu | ELONGATION FACTOR G (Staphylococcusaureus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF03764(EFG_IV)PF14492(EFG_II) | 4 | TYR A 33ASP A 189VAL A 267GLY A 266 | None | 0.94A | 5nzyA-3zzuA:undetectable | 5nzyA-3zzuA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4aj9 | CATALASE-3 (Neurosporacrassa) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 389ASP A 379VAL A 173GLY A 174 | HEM A1715 (-3.7A)NoneHEM A1715 (-4.8A)HEM A1715 (-3.8A) | 0.91A | 5nzyA-4aj9A:undetectable | 5nzyA-4aj9A:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cab | CATALASE (Deinococcusradiodurans) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 369ASP A 359VAL A 157GLY A 158 | HEM A 537 (-4.2A)NoneHEM A 537 (-4.9A)HEM A 537 (-4.0A) | 0.91A | 5nzyA-4cabA:undetectable | 5nzyA-4cabA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4chl | PERSULFIDEDIOXYGENASE ETHE1,MITOCHONDRIAL (Homo sapiens) |
PF00753(Lactamase_B) | 4 | ASP A 146VAL A 205GLY A 187ARG A 209 | None | 1.02A | 5nzyA-4chlA:6.4 | 5nzyA-4chlA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4csi | CELLULASE (Humicola grisea) |
PF00840(Glyco_hydro_7) | 4 | PRO A 408ASP A 180VAL A 105GLY A 106 | None | 0.96A | 5nzyA-4csiA:undetectable | 5nzyA-4csiA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dvj | PUTATIVEZINC-DEPENDENTALCOHOLDEHYDROGENASEPROTEIN (Rhizobium etli) |
PF08240(ADH_N)PF13602(ADH_zinc_N_2) | 4 | THR A 294PRO A 296ASP A 88GLY A 307 | None | 0.96A | 5nzyA-4dvjA:3.4 | 5nzyA-4dvjA:18.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e1j | GLYCEROL KINASE (Sinorhizobiummeliloti) |
PF00370(FGGY_N)PF02782(FGGY_C) | 4 | TYR A 27GLN A 21VAL A 42GLY A 51 | None NA A 602 ( 4.5A)NoneNone | 0.98A | 5nzyA-4e1jA:undetectable | 5nzyA-4e1jA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e37 | CATALASE (Pseudomonasaeruginosa) |
PF00199(Catalase)PF06628(Catalase-rel) | 4 | TYR A 338ASP A 328VAL A 126GLY A 127 | HEM A 500 (-4.0A)NoneHEM A 500 (-4.9A)HEM A 500 (-3.8A) | 0.97A | 5nzyA-4e37A:undetectable | 5nzyA-4e37A:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6w | CLBP PEPTIDASE (Escherichiacoli) |
PF00144(Beta-lactamase) | 4 | THR A 147ASP A 192VAL A 105GLY A 102 | None | 0.94A | 5nzyA-4e6wA:undetectable | 5nzyA-4e6wA:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hcy | THIAMINASE-I (Naegleriagruberi) |
no annotation | 4 | PRO A 126TYR A 246VAL A 217GLY A 220 | None | 0.93A | 5nzyA-4hcyA:undetectable | 5nzyA-4hcyA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k70 | UL37 (Suidalphaherpesvirus1) |
PF03970(Herpes_UL37_1) | 4 | ASP A 315VAL A 290GLY A 289ARG A 285 | None | 1.03A | 5nzyA-4k70A:undetectable | 5nzyA-4k70A:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m9x | CELL DEATH PROTEIN 4 (Caenorhabditiselegans) |
PF00619(CARD)PF00931(NB-ARC) | 4 | THR A 332PRO A 330VAL A 290GLY A 159 | NoneATP A 602 (-4.6A)NoneNone | 1.03A | 5nzyA-4m9xA:3.2 | 5nzyA-4m9xA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mh0 | RAP GUANINENUCLEOTIDE EXCHANGEFACTOR 4RAS-RELATED PROTEINRAP-1B (Homo sapiens;Mus musculus) |
PF00027(cNMP_binding)PF00071(Ras)PF00617(RasGEF)PF00618(RasGEF_N) | 4 | THR R 65GLN R 63ASP E 796GLY E 720 | None | 0.97A | 5nzyA-4mh0R:undetectable | 5nzyA-4mh0R:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mzw | GLUTATHIONES-TRANSFERASE (Streptococcussanguinis) |
PF02798(GST_N)PF13410(GST_C_2) | 4 | TYR A 45GLN A 259VAL A -12GLY A -13 | None | 0.82A | 5nzyA-4mzwA:undetectable | 5nzyA-4mzwA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ol0 | TRANSPORTIN-3 (Homo sapiens) |
PF08389(Xpo1) | 4 | GLN B 682ASP B 723VAL B 708GLY B 712 | None | 1.05A | 5nzyA-4ol0B:undetectable | 5nzyA-4ol0B:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q8h | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN2 (Saccharomycescerevisiae) |
PF00929(RNase_T)PF13423(UCH_1) | 4 | THR A 516GLN A 521VAL A 533GLY A 551 | None | 0.84A | 5nzyA-4q8hA:undetectable | 5nzyA-4q8hA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfw | ACYL-COATHIOESTERASE II (Yersinia pestis) |
PF13622(4HBT_3) | 4 | THR A 120PRO A 122TYR A 179GLN A 264 | None | 1.04A | 5nzyA-4qfwA:undetectable | 5nzyA-4qfwA:21.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s28 | PHOSPHOMETHYLPYRIMIDINE SYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01964(ThiC_Rad_SAM) | 4 | THR A 261GLN A 287VAL A 280GLY A 281 | None | 0.99A | 5nzyA-4s28A:undetectable | 5nzyA-4s28A:19.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tsh | SURFACE PROTEINADHESIN (Streptococcusmutans) |
PF16364(Antigen_C)no annotation | 4 | THR B1160PRO B1159GLN B1312GLY A 57 | None | 0.97A | 5nzyA-4tshB:undetectable | 5nzyA-4tshB:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yme | SENSORY BOX/GGDEFFAMILY PROTEIN (Caulobactervibrioides) |
PF00990(GGDEF) | 4 | PRO A 503TYR A 502VAL A 397GLY A 401 | None | 0.95A | 5nzyA-4ymeA:undetectable | 5nzyA-4ymeA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zhj | MG-CHELATASE SUBUNITCHLH (Synechocystissp. PCC 6803) |
PF02514(CobN-Mg_chel)PF11965(DUF3479) | 4 | TYR A 699ASP A 739VAL A 747GLY A 748 | None | 0.84A | 5nzyA-4zhjA:undetectable | 5nzyA-4zhjA:15.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 6 | THR A 700PRO A 702TYR A 704GLN A 718ASP A 736VAL A1018 | None | 0.59A | 5nzyA-5ahrA:47.6 | 5nzyA-5ahrA:99.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 6 | THR A 700PRO A 702TYR A 704GLN A 718VAL A1018GLY A1019 | None | 0.57A | 5nzyA-5ahrA:47.6 | 5nzyA-5ahrA:99.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 5 | THR A 700PRO A 702VAL A1018GLY A1019ARG A1024 | None | 0.61A | 5nzyA-5ahrA:47.6 | 5nzyA-5ahrA:99.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5awm | STRESS-ACTIVATEDPROTEIN KINASE JNK (Drosophilamelanogaster) |
PF00069(Pkinase) | 4 | PRO A 152TYR A 189VAL A 221GLY A 220 | None | 1.03A | 5nzyA-5awmA:undetectable | 5nzyA-5awmA:21.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c5y | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Colwelliapsychrerythraea) |
PF01791(DeoC) | 4 | PRO A 178TYR A 212VAL A 203GLY A 202 | None | 1.02A | 5nzyA-5c5yA:2.1 | 5nzyA-5c5yA:18.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d3q | DYNAMIN-1,DYNAMIN-1 (Homo sapiens) |
PF00350(Dynamin_N)PF01031(Dynamin_M) | 4 | THR A 200GLN A 284VAL A 234GLY A 233 | None | 0.98A | 5nzyA-5d3qA:undetectable | 5nzyA-5d3qA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ej2 | CARVEOLDEHYDROGENASE (Mycobacteriumavium) |
PF13561(adh_short_C2) | 4 | THR A 175ASP A 134VAL A 185GLY A 184 | MPD A 302 ( 4.2A)NoneNoneNone | 0.82A | 5nzyA-5ej2A:undetectable | 5nzyA-5ej2A:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h9u | S-ADENOSYLMETHIONINESYNTHASE (Thermusthermophilus) |
no annotation | 4 | THR C 59ASP C 130VAL C 126ARG C 125 | None | 0.93A | 5nzyA-5h9uC:undetectable | 5nzyA-5h9uC:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdf | HYDROLASE (Streptomycesflocculus) |
no annotation | 4 | THR B 197VAL B 99GLY B 187ARG B 136 | None | 0.98A | 5nzyA-5hdfB:undetectable | 5nzyA-5hdfB:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hh3 | OXYA PROTEIN (Actinoplanesteichomyceticus) |
PF00067(p450) | 4 | THR A 149GLN A 115VAL A 208GLY A 207 | HEM A 401 ( 4.7A)NoneNoneNone | 0.76A | 5nzyA-5hh3A:undetectable | 5nzyA-5hh3A:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i84 | PHOSPHATE-BINDINGPROTEIN PSTS (Xanthomonascitri) |
PF12849(PBP_like_2) | 4 | THR A 188TYR A 217VAL A 204GLY A 198 | PO4 A 403 ( 4.6A)NoneNoneNone | 1.00A | 5nzyA-5i84A:undetectable | 5nzyA-5i84A:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ip9 | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB2 (Saccharomycescerevisiae) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF04566(RNA_pol_Rpb2_4)PF04567(RNA_pol_Rpb2_5) | 4 | THR B 549PRO B 551VAL B 585GLY B 584 | None | 0.76A | 5nzyA-5ip9B:undetectable | 5nzyA-5ip9B:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nnl | INACTIVEDIHYDROOROTASE-LIKEDOMAIN (Chaetomiumthermophilum) |
no annotation | 4 | THR A1549ASP A1759VAL A1828GLY A1842 | None | 0.96A | 5nzyA-5nnlA:undetectable | 5nzyA-5nnlA:21.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nz7 | CELLODEXTRINPHOSPHORYLASE (Ruminiclostridiumthermocellum) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | ASP A 621VAL A 609GLY A 610ARG A 656 | None | 0.99A | 5nzyA-5nz7A:undetectable | 5nzyA-5nz7A:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oko | PHOSPHATIDYLINOSITOL3,4,5-TRISPHOSPHATE5-PHOSPHATASE 2 (Homo sapiens) |
PF03372(Exo_endo_phos) | 4 | THR A 430ASP A 478VAL A 546GLY A 545 | None | 0.79A | 5nzyA-5okoA:undetectable | 5nzyA-5okoA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wnn | PHOSPHATE-BINDINGPROTEIN PSTS (Burkholderiapseudomallei) |
PF12849(PBP_like_2) | 4 | THR A 184TYR A 213VAL A 200GLY A 194 | None | 0.93A | 5nzyA-5wnnA:undetectable | 5nzyA-5wnnA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | THR A 281ASP A 195VAL A 166GLY A 165 | NAD A 500 (-4.0A)ADN A 501 (-2.7A)NoneNone | 0.85A | 5nzyA-6aphA:2.3 | 5nzyA-6aphA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cgm | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (Bacillussubtilis) |
no annotation | 4 | THR A 305PRO A 303VAL A 223GLY A 222 | None | 0.90A | 5nzyA-6cgmA:undetectable | 5nzyA-6cgmA:11.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d43 | TRIOSEPHOSPHATEISOMERASE (Homo sapiens) |
no annotation | 4 | THR B 204ASP B 36VAL B 40GLY B 9 | None | 0.91A | 5nzyA-6d43B:2.7 | 5nzyA-6d43B:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eub | ANGIOPOIETIN-RELATEDPROTEIN 4 (Homo sapiens) |
no annotation | 4 | TYR A 244ASP A 332GLY A 361ARG A 230 | None | 0.95A | 5nzyA-6eubA:undetectable | 5nzyA-6eubA:12.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f3m | - (-) |
no annotation | 4 | THR B 298ASP B 198VAL B 169GLY B 168 | NAD B 501 (-4.1A)ADN B 502 (-2.7A)NoneNone | 0.90A | 5nzyA-6f3mB:2.1 | 5nzyA-6f3mB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gbn | - (-) |
no annotation | 4 | THR A 279ASP A 193VAL A 164GLY A 163 | NAD A 502 (-4.1A)ADN A 501 (-2.7A)NoneNone | 0.82A | 5nzyA-6gbnA:2.3 | 5nzyA-6gbnA:undetectable |