SIMILAR PATTERNS OF AMINO ACIDS FOR 5NZY_A_CE3A1102
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cbg | CYANOGENICBETA-GLUCOSIDASE (Trifoliumrepens) |
PF00232(Glyco_hydro_1) | 4 | ASN A 398THR A 252ILE A 395GLY A 322 | None | 0.99A | 5nzyA-1cbgA:1.4 | 5nzyA-1cbgA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1egz | ENDOGLUCANASE Z (Dickeyachrysanthemi) |
PF00150(Cellulase) | 4 | PHE A 113THR A 190ILE A 130GLY A 166 | None | 0.96A | 5nzyA-1egzA:1.4 | 5nzyA-1egzA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0b | CELLULASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | ASN A 42PHE A 43THR A 89ILE A 62 | None | 0.88A | 5nzyA-1h0bA:undetectable | 5nzyA-1h0bA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvm | 4-HYDROXY-2-OXOVALERATE ALDOLASE (Pseudomonas sp.CF600) |
PF00682(HMGL-like)PF07836(DmpG_comm) | 4 | THR A 15GLN A 272ILE A 23GLY A 19 | None | 0.89A | 5nzyA-1nvmA:0.0 | 5nzyA-1nvmA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9b | HYPOTHETICALSHIKIMATE5-DEHYDROGENASE-LIKEPROTEIN YDIB (Escherichiacoli) |
PF08501(Shikimate_dh_N) | 4 | THR A 93GLN A 26ILE A 10GLY A 65 | None | 0.97A | 5nzyA-1o9bA:2.2 | 5nzyA-1o9bA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pby | QUINOHEMOPROTEINAMINE DEHYDROGENASE60 KDA SUBUNIT (Paracoccusdenitrificans) |
PF09098(Dehyd-heme_bind)PF09099(Qn_am_d_aIII)PF09100(Qn_am_d_aIV)PF14930(Qn_am_d_aII) | 4 | ARG A 254GLN A 242ILE A 243GLY A 253 | None | 0.94A | 5nzyA-1pbyA:undetectable | 5nzyA-1pbyA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tvp | CELLULASE (Pseudoalteromonashaloplanktis) |
PF00150(Cellulase) | 4 | PHE A 115THR A 192ILE A 132GLY A 168 | None | 0.98A | 5nzyA-1tvpA:2.7 | 5nzyA-1tvpA:22.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tvt | TRANSACTIVATORPROTEIN (Equineinfectiousanemia virus) |
PF00539(Tat) | 4 | ASN A 58GLN A 66ILE A 65GLY A 68 | None | 0.98A | 5nzyA-1tvtA:undetectable | 5nzyA-1tvtA:11.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcl | HEMOLYTIC LECTINCEL-III (Cucumariaechinata) |
PF00652(Ricin_B_lectin) | 4 | PHE A 144GLN A 142ILE A 122GLY A 124 | NoneNoneNone CA A1002 (-4.3A) | 0.94A | 5nzyA-1vclA:undetectable | 5nzyA-1vclA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vki | HYPOTHETICAL PROTEINATU3699 (Agrobacteriumfabrum) |
PF04073(tRNA_edit) | 4 | PHE A 15THR A 107ILE A 112GLY A 110 | None | 0.98A | 5nzyA-1vkiA:0.9 | 5nzyA-1vkiA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xv5 | DNAALPHA-GLUCOSYLTRANSFERASE (Escherichiavirus T4) |
PF11440(AGT) | 4 | ASN A1095THR A1130ILE A1093GLY A1126 | None | 0.95A | 5nzyA-1xv5A:undetectable | 5nzyA-1xv5A:22.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ypx | PUTATIVE VITAMIN-B12INDEPENDENTMETHIONINE SYNTHASEFAMILY PROTEIN (Listeriamonocytogenes) |
PF01717(Meth_synt_2) | 4 | ASN A 43THR A 18ILE A 41GLY A 20 | None | 0.99A | 5nzyA-1ypxA:2.5 | 5nzyA-1ypxA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z8l | GLUTAMATECARBOXYPEPTIDASE II (Homo sapiens) |
PF02225(PA)PF04253(TFR_dimer)PF04389(Peptidase_M28) | 4 | ASN A 451ARG A 580ILE A 450GLY A 581 | None | 0.99A | 5nzyA-1z8lA:undetectable | 5nzyA-1z8lA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zsq | MYOTUBULARIN-RELATEDPROTEIN 2 (Homo sapiens) |
PF02893(GRAM)PF06602(Myotub-related) | 4 | ASN A 523ARG A 528GLN A 526GLY A 529 | None | 0.98A | 5nzyA-1zsqA:undetectable | 5nzyA-1zsqA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ag1 | BENZALDEHYDE LYASE (Pseudomonasfluorescens) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | THR A 135GLN A 169ILE A 4GLY A 6 | None | 0.70A | 5nzyA-2ag1A:3.3 | 5nzyA-2ag1A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bjo | ORGANICHYDROPEROXIDERESISTANCE PROTEINOHRB (Bacillussubtilis) |
PF02566(OsmC) | 4 | ASN A 43ARG A 14ILE A 29GLY A 13 | None | 0.90A | 5nzyA-2bjoA:undetectable | 5nzyA-2bjoA:18.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwa | ENDOGLUCANASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | ASN A 42PHE A 43THR A 89ILE A 62 | None | 0.84A | 5nzyA-2bwaA:undetectable | 5nzyA-2bwaA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2czy | PAIRED AMPHIPATHICHELIX PROTEIN SIN3B (Mus musculus) |
PF02671(PAH) | 4 | PHE A 58ARG A 78ILE A 61GLY A 74 | None | 0.83A | 5nzyA-2czyA:undetectable | 5nzyA-2czyA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fff | PENICILLIN-BINDINGPROTEIN 1B (Streptococcuspneumoniae) |
PF00905(Transpeptidase) | 4 | THR B 667GLN B 705ILE B 711GLY B 713 | None | 0.91A | 5nzyA-2fffB:undetectable | 5nzyA-2fffB:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gjx | BETA-HEXOSAMINIDASEALPHA CHAIN (Homo sapiens) |
PF00728(Glyco_hydro_20)PF14845(Glycohydro_20b2) | 4 | ASN A 379THR A 387GLN A 357ILE A 356 | None | 0.97A | 5nzyA-2gjxA:undetectable | 5nzyA-2gjxA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gk1 | BETA-HEXOSAMINIDASESUBUNIT ALPHA (Homo sapiens) |
no annotation | 4 | ASN I 379THR I 387GLN I 357ILE I 356 | None | 0.94A | 5nzyA-2gk1I:undetectable | 5nzyA-2gk1I:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jch | PENICILLIN-BINDINGPROTEIN 1B (Streptococcuspneumoniae) |
PF00905(Transpeptidase)PF00912(Transgly) | 4 | THR A 667GLN A 705ILE A 711GLY A 713 | None | 0.92A | 5nzyA-2jchA:undetectable | 5nzyA-2jchA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l7e | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 14 (Saccharomycescerevisiae) |
PF03366(YEATS) | 4 | ASN A 123GLN A 119ILE A 120GLY A 97 | None | 0.98A | 5nzyA-2l7eA:undetectable | 5nzyA-2l7eA:16.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lfe | E3 UBIQUITIN-PROTEINLIGASE HECW2 (Homo sapiens) |
PF16562(HECW_N) | 4 | ASN A 110THR A 116ILE A 121GLY A 119 | None | 0.93A | 5nzyA-2lfeA:undetectable | 5nzyA-2lfeA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2op6 | HEAT SHOCK 70 KDAPROTEIN D (Caenorhabditiselegans) |
PF00012(HSP70) | 4 | ASN A 483PHE A 484ILE A 467GLY A 427 | None | 1.00A | 5nzyA-2op6A:undetectable | 5nzyA-2op6A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p38 | PROTEIN INVOLVED INRIBOSOMAL BIOGENESIS (Pyrococcusabyssi) |
PF03657(UPF0113) | 4 | ASN A 146PHE A 153ILE A 145GLY A 126 | None | 0.89A | 5nzyA-2p38A:undetectable | 5nzyA-2p38A:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 4 | PHE A 238THR A 214GLN A 234GLY A 217 | None | 0.95A | 5nzyA-2pg6A:undetectable | 5nzyA-2pg6A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvz | PRPF METHYLACONITATEISOMERASE (Shewanellaoneidensis) |
PF04303(PrpF) | 4 | THR A 323GLN A 141ILE A 148GLY A 108 | EDO A1005 (-3.1A)NoneNoneEDO A1005 (-3.8A) | 0.98A | 5nzyA-2pvzA:undetectable | 5nzyA-2pvzA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdx | FERREDOXIN REDUCTASE (Pseudomonasaeruginosa) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 4 | ARG A 190THR A 181GLN A 191GLY A 189 | SO4 A 401 (-4.0A)SO4 A 401 (-3.1A)NoneNone | 0.85A | 5nzyA-2qdxA:undetectable | 5nzyA-2qdxA:24.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r47 | UNCHARACTERIZEDPROTEIN MTH_862 (Methanothermobacterthermautotrophicus) |
PF09897(DUF2124) | 4 | ASN A 52THR A 69GLN A 41GLY A 72 | None | 0.95A | 5nzyA-2r47A:3.1 | 5nzyA-2r47A:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vut | NITROGEN METABOLITEREPRESSION REGULATORNMRA (Aspergillusnidulans) |
PF05368(NmrA) | 4 | PHE A 181THR A 219ILE A 152GLY A 151 | NoneNoneNAD A1353 (-4.3A)NAD A1353 (-4.7A) | 0.93A | 5nzyA-2vutA:undetectable | 5nzyA-2vutA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wqd | PHOSPHOENOLPYRUVATE-PROTEINPHOSPHOTRANSFERASE (Staphylococcusaureus) |
PF00391(PEP-utilizers)PF02896(PEP-utilizers_C)PF05524(PEP-utilisers_N) | 4 | ARG A 188THR A 189ILE A 8GLY A 187 | None | 0.89A | 5nzyA-2wqdA:1.6 | 5nzyA-2wqdA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xrc | HUMAN COMPLEMENTFACTOR I (Homo sapiens) |
PF00057(Ldl_recept_a)PF00089(Trypsin)PF00530(SRCR) | 4 | ASN A 159THR A 185GLN A 189GLY A 187 | NAG A 659 (-1.9A)NoneNoneNone | 0.92A | 5nzyA-2xrcA:undetectable | 5nzyA-2xrcA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yfn | ALPHA-GALACTOSIDASE-SUCROSE KINASE AGASK ([Ruminococcus]gnavus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | ARG A 203GLN A 551ILE A 550GLY A 553 | None | 1.01A | 5nzyA-2yfnA:undetectable | 5nzyA-2yfnA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yu6 | YTHDOMAIN-CONTAININGPROTEIN 2 (Homo sapiens) |
PF04146(YTH) | 4 | ASN A 20GLN A 26ILE A 23GLY A 28 | None | 0.97A | 5nzyA-2yu6A:undetectable | 5nzyA-2yu6A:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z22 | PERIPLASMICPHOSPHATE-BINDINGPROTEIN (Yersinia pestis) |
no annotation | 5 | ASN X 48THR X 5GLN X 44ILE X 45GLY X 6 | None | 1.26A | 5nzyA-2z22X:undetectable | 5nzyA-2z22X:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zym | SOLUTE-BINDINGPROTEIN (Thermoactinomycesvulgaris) |
PF13416(SBP_bac_8) | 4 | PHE A 189THR A 90ILE A 353GLY A 86 | None | 0.92A | 5nzyA-2zymA:undetectable | 5nzyA-2zymA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7m | CELLULASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | ASN A 42PHE A 43THR A 80ILE A 62 | None | 0.89A | 5nzyA-3b7mA:undetectable | 5nzyA-3b7mA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bwt | PROTEIN PUF4 (Saccharomycescerevisiae) |
PF00806(PUF) | 4 | THR A 650GLN A 691ILE A 690GLY A 686 | None | 0.87A | 5nzyA-3bwtA:undetectable | 5nzyA-3bwtA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0k | UPF0064 PROTEIN YCCW (Escherichiacoli) |
PF10672(Methyltrans_SAM) | 4 | ASN A 322GLN A 327ILE A 326GLY A 361 | None | 0.92A | 5nzyA-3c0kA:2.0 | 5nzyA-3c0kA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cer | POSSIBLEEXOPOLYPHOSPHATASE-LIKE PROTEIN (Bifidobacteriumlongum) |
PF02541(Ppx-GppA) | 4 | PHE A 78THR A 95ILE A 28GLY A 24 | NoneSO4 A 344 ( 3.5A)NoneSO4 A 344 (-3.3A) | 0.84A | 5nzyA-3cerA:undetectable | 5nzyA-3cerA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A1249PHE A1255THR A 74GLY A 71 | NoneNoneADP A 502 (-4.0A)ADP A 502 (-3.3A) | 0.90A | 5nzyA-3cmtA:2.5 | 5nzyA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A2249PHE A2255THR A1074GLY A1071 | NoneNoneADP A1502 (-3.9A)ADP A1502 (-3.4A) | 0.90A | 5nzyA-3cmtA:2.5 | 5nzyA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A3249PHE A3255THR A2074GLY A2071 | NoneNoneADP A2502 (-3.8A)ADP A2502 (-3.4A) | 0.90A | 5nzyA-3cmtA:2.5 | 5nzyA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A4249PHE A4255THR A3074GLY A3071 | NoneNoneADP A3502 (-3.7A)ADP A3502 (-3.4A) | 0.90A | 5nzyA-3cmtA:2.5 | 5nzyA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A1249PHE A1255THR A 74GLY A 71 | NoneNoneADP A 502 (-3.9A)ADP A 502 (-3.0A) | 0.92A | 5nzyA-3cmuA:undetectable | 5nzyA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A2249PHE A2255THR A1074GLY A1071 | NoneNoneADP A1502 (-3.5A)ADP A1502 (-2.8A) | 0.95A | 5nzyA-3cmuA:undetectable | 5nzyA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A3249PHE A3255THR A2074GLY A2071 | NoneNoneADP A2502 (-3.9A)ADP A2502 (-2.8A) | 1.01A | 5nzyA-3cmuA:undetectable | 5nzyA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A4249PHE A4255THR A3074GLY A3071 | NoneNoneADP A3502 (-3.7A)ADP A3502 (-2.7A) | 0.95A | 5nzyA-3cmuA:undetectable | 5nzyA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A5249PHE A5255THR A4074GLY A4071 | NoneNoneADP A4502 (-3.8A)ADP A4502 (-2.8A) | 0.95A | 5nzyA-3cmuA:undetectable | 5nzyA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e4b | ALGK (Pseudomonasfluorescens) |
no annotation | 4 | ARG A 208THR A 210GLN A 201GLY A 205 | None | 0.98A | 5nzyA-3e4bA:undetectable | 5nzyA-3e4bA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3erv | PUTATIVE C39-LIKEPEPTIDASE (Bacillusanthracis) |
PF13529(Peptidase_C39_2) | 4 | ASN A 95THR A 75ILE A 119GLY A 71 | NoneNoneEDO A 1 (-3.9A)None | 0.95A | 5nzyA-3ervA:undetectable | 5nzyA-3ervA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3es5 | PUTATIVE CAPSIDPROTEIN (Penicilliumstoloniferumvirus F) |
no annotation | 4 | ARG A 97GLN A 99ILE A 98GLY A 95 | None | 0.92A | 5nzyA-3es5A:undetectable | 5nzyA-3es5A:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gjy | SPERMIDINE SYNTHASE (Corynebacteriumglutamicum) |
no annotation | 4 | ASN A 236THR A 73ILE A 238GLY A 74 | None | 0.96A | 5nzyA-3gjyA:undetectable | 5nzyA-3gjyA:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gse | MENAQUINONE-SPECIFICISOCHORISMATESYNTHASE (Yersinia pestis) |
PF00425(Chorismate_bind) | 4 | ARG A 134THR A 139GLN A 39GLY A 34 | None | 0.69A | 5nzyA-3gseA:undetectable | 5nzyA-3gseA:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h0g | DNA-DIRECTED RNAPOLYMERASE IISUBUNIT RPB1 (Schizosaccharomycespombe) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04990(RNA_pol_Rpb1_7)PF04992(RNA_pol_Rpb1_6)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4) | 4 | THR A1144GLN A1140ILE A1141GLY A1281 | None | 0.94A | 5nzyA-3h0gA:undetectable | 5nzyA-3h0gA:11.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ico | 6-PHOSPHOGLUCONOLACTONASE (Mycobacteriumtuberculosis) |
PF01182(Glucosamine_iso) | 4 | THR A 233GLN A 192ILE A 191GLY A 229 | None | 0.93A | 5nzyA-3icoA:2.2 | 5nzyA-3icoA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3im8 | MALONYL ACYL CARRIERPROTEIN TRANSACYLASE (Streptococcuspneumoniae) |
PF00698(Acyl_transf_1) | 4 | ASN A 268PHE A 269GLN A 262ILE A 266 | None | 0.94A | 5nzyA-3im8A:undetectable | 5nzyA-3im8A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j7a | 40S RIBOSOMALPROTEIN ES6 (Plasmodiumfalciparum) |
PF01092(Ribosomal_S6e) | 4 | PHE H 77THR H 69ILE H 64GLY H 99 | None | 0.94A | 5nzyA-3j7aH:undetectable | 5nzyA-3j7aH:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | ASN A 197THR A 205GLN A 200GLY A 35 | None | 0.96A | 5nzyA-3ju8A:undetectable | 5nzyA-3ju8A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3juu | PORPHYRANASE B (Zobelliagalactanivorans) |
PF00722(Glyco_hydro_16) | 4 | ASN A 168GLN A 165ILE A 166GLY A 164 | None | 0.99A | 5nzyA-3juuA:undetectable | 5nzyA-3juuA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m9u | FARNESYL-DIPHOSPHATESYNTHASE (Lactobacillusbrevis) |
PF00348(polyprenyl_synt) | 4 | THR A 55GLN A 193ILE A 197GLY A 195 | None | 0.94A | 5nzyA-3m9uA:undetectable | 5nzyA-3m9uA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mep | UNCHARACTERIZEDPROTEIN ECA2234 (Pectobacteriumatrosepticum) |
PF07081(DUF1349) | 4 | PHE A 73THR A 118ILE A 96GLY A 106 | None | 0.90A | 5nzyA-3mepA:undetectable | 5nzyA-3mepA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mi6 | ALPHA-GALACTOSIDASE (Lactobacillusbrevis) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | ARG A 204GLN A 560ILE A 559GLY A 562 | None | 0.93A | 5nzyA-3mi6A:undetectable | 5nzyA-3mi6A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8a | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF13468(Glyoxalase_3) | 4 | PHE A 40ARG A 264ILE A 263GLY A 265 | None | 0.80A | 5nzyA-3p8aA:undetectable | 5nzyA-3p8aA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pqs | TRANSFERRIN-BINDINGPROTEIN (Actinobacilluspleuropneumoniae) |
PF01298(TbpB_B_D)PF17483(TbpB_C)PF17484(TbpB_A) | 4 | ASN A 144PHE A 200ILE A 146GLY A 286 | None | 1.00A | 5nzyA-3pqsA:undetectable | 5nzyA-3pqsA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tx2 | PROBABLE6-PHOSPHOGLUCONOLACTONASE (Mycobacteroidesabscessus) |
PF01182(Glucosamine_iso) | 4 | THR A 234GLN A 193ILE A 192GLY A 230 | None | 0.98A | 5nzyA-3tx2A:undetectable | 5nzyA-3tx2A:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a4z | ANTIVIRAL HELICASESKI2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 4 | ASN A 450THR A 798GLN A 759GLY A 755 | None | 1.01A | 5nzyA-4a4zA:3.0 | 5nzyA-4a4zA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0a | IQ MOTIF AND SEC7DOMAIN-CONTAININGPROTEIN 1 (Homo sapiens) |
PF01369(Sec7)PF16453(IQ_SEC7_PH) | 4 | PHE A 413ARG A 449THR A 592ILE A 452 | None | 0.98A | 5nzyA-4c0aA:undetectable | 5nzyA-4c0aA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e1e | FARNESYLPYROPHOSPHATESYNTHASE (Trypanosomacruzi) |
PF00348(polyprenyl_synt) | 4 | PHE A 321THR A 208GLN A 249GLY A 243 | NoneIPE A 405 ( 4.6A)NoneNone | 0.92A | 5nzyA-4e1eA:undetectable | 5nzyA-4e1eA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fnq | ALPHA-GALACTOSIDASEAGAB (Geobacillusstearothermophilus) |
PF02065(Melibiase)PF16874(Glyco_hydro_36C)PF16875(Glyco_hydro_36N) | 4 | ARG A 203GLN A 559ILE A 558GLY A 561 | None | 1.01A | 5nzyA-4fnqA:undetectable | 5nzyA-4fnqA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j05 | PHOSPHATETRANSPORTER (Serendipitaindica) |
PF00083(Sugar_tr) | 4 | ASN A 431PHE A 426THR A 496GLY A 492 | PO4 A 600 (-3.1A)NoneNoneNone | 0.86A | 5nzyA-4j05A:undetectable | 5nzyA-4j05A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4je3 | CENTRAL KINETOCHORESUBUNIT CHL4CENTRAL KINETOCHORESUBUNIT IML3 (Saccharomycescerevisiae) |
PF05238(CENP-N)no annotation | 4 | ASN B 405THR A 153ILE B 409GLY B 412 | None | 1.01A | 5nzyA-4je3B:undetectable | 5nzyA-4je3B:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jpw | HEAVY CHAIN OFANTIBODY 12A21 (Homo sapiens) |
PF07654(C1-set)PF07686(V-set) | 4 | ARG H 66GLN H 68ILE H 67GLY H 65 | None | 1.00A | 5nzyA-4jpwH:undetectable | 5nzyA-4jpwH:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jzx | FARNESYLPYROPHOSPHATESYNTHASE (Leishmaniamajor) |
PF00348(polyprenyl_synt) | 4 | PHE A 321THR A 208GLN A 249GLY A 243 | NoneIPE A 401 ( 3.4A)NoneNone | 0.95A | 5nzyA-4jzxA:undetectable | 5nzyA-4jzxA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k1c | VACUOLAR CALCIUM IONTRANSPORTER (Saccharomycescerevisiae) |
PF01699(Na_Ca_ex) | 4 | ASN A 80THR A 261ILE A 256GLY A 259 | None | 0.91A | 5nzyA-4k1cA:undetectable | 5nzyA-4k1cA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ktp | GLYCOSIDE HYDROLASEFAMILY 65 CENTRALCATALYTIC ([Bacillus]selenitireducens) |
PF03632(Glyco_hydro_65m)PF03633(Glyco_hydro_65C)PF03636(Glyco_hydro_65N) | 4 | PHE A 666THR A 45ILE A 27GLY A 30 | None | 0.96A | 5nzyA-4ktpA:undetectable | 5nzyA-4ktpA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l8j | PUTATIVE EFFLUXTRANSPORTER (Bacteroideseggerthii) |
PF16576(HlyD_D23) | 4 | ASN A 69GLN A 66ILE A 67GLY A 65 | None | 0.90A | 5nzyA-4l8jA:undetectable | 5nzyA-4l8jA:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m1r | CELLULASE 5 (soil metagenome) |
PF00150(Cellulase) | 4 | PHE A 112THR A 190ILE A 129GLY A 165 | None | 0.96A | 5nzyA-4m1rA:undetectable | 5nzyA-4m1rA:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ml9 | UNCHARACTERIZEDPROTEIN (Sebaldellatermitidis) |
PF00977(His_biosynth) | 4 | PHE A 247THR A 32ILE A 239GLY A 258 | NoneGOL A 307 (-3.6A)NoneGOL A 307 (-3.6A) | 1.00A | 5nzyA-4ml9A:undetectable | 5nzyA-4ml9A:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o4f | INOSITOLHEXAKISPHOSPHATEKINASE (Entamoebahistolytica) |
PF03770(IPK) | 4 | PHE A 232THR A 61ILE A 64GLY A 62 | None | 0.97A | 5nzyA-4o4fA:undetectable | 5nzyA-4o4fA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj3 | INTRON-BINDINGPROTEIN AQUARIUS (Homo sapiens) |
PF13086(AAA_11)PF13087(AAA_12)PF16399(Aquarius_N) | 4 | PHE A 802THR A 819ILE A 810GLY A 813 | None | 1.01A | 5nzyA-4pj3A:2.1 | 5nzyA-4pj3A:12.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s2t | PROTEIN APP-1 (Caenorhabditiselegans) |
PF00557(Peptidase_M24)PF01321(Creatinase_N)PF16188(Peptidase_M24_C)PF16189(Creatinase_N_2) | 4 | ASN P 212ARG P 214ILE P 213GLY P 215 | None | 0.84A | 5nzyA-4s2tP:undetectable | 5nzyA-4s2tP:19.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 6 | ASN A 938PHE A 939ARG A 960THR A 962ILE A 986GLY A 988 | None | 0.60A | 5nzyA-5ahrA:47.6 | 5nzyA-5ahrA:99.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eny | POLYKETIDE SYNTHASEPKSL (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | ASN A 376PHE A 379THR A 369GLY A 336 | None | 0.79A | 5nzyA-5enyA:2.1 | 5nzyA-5enyA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gmh | TOLL-LIKE RECEPTOR 7 (Macaca mulatta) |
PF00560(LRR_1)PF13306(LRR_5)PF13855(LRR_8) | 4 | ARG A 378THR A 406GLN A 323GLY A 379 | None | 0.93A | 5nzyA-5gmhA:undetectable | 5nzyA-5gmhA:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hxa | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Paraburkholderiaxenovorans) |
PF00982(Glyco_transf_20) | 4 | PHE A 286ARG A 333ILE A 330GLY A 332 | NoneEDO A 506 ( 3.1A)NoneNone | 0.96A | 5nzyA-5hxaA:undetectable | 5nzyA-5hxaA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2u | CELLULASE (soil metagenome) |
PF00150(Cellulase) | 4 | PHE A 123THR A 200ILE A 140GLY A 175 | None | 0.93A | 5nzyA-5i2uA:2.2 | 5nzyA-5i2uA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ik8 | LAMININ SUBUNITALPHA-2 (Mus musculus) |
PF00054(Laminin_G_1)PF02210(Laminin_G_2) | 4 | PHE A2799THR A2866ILE A2848GLY A2855 | None | 0.99A | 5nzyA-5ik8A:undetectable | 5nzyA-5ik8A:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iku | COLLAGENASE (Hathewayahistolytica) |
PF04151(PPC) | 4 | PHE A 815THR A 836ILE A 825GLY A 852 | None | 1.00A | 5nzyA-5ikuA:undetectable | 5nzyA-5ikuA:21.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9s | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (MANNOPINE) (Agrobacteriumfabrum) |
PF13416(SBP_bac_8) | 4 | ASN A 178PHE A 179GLN A 242GLY A 241 | None | 0.99A | 5nzyA-5l9sA:undetectable | 5nzyA-5l9sA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m2m | LLAMA NANOBODY VHH3 (Lama glama) |
no annotation | 4 | ASN D 62ARG D 55ILE D 56GLY D 40 | ASN D 62 ( 0.6A)ARG D 55 ( 0.6A)ILE D 56 ( 0.6A)GLY D 40 ( 0.0A) | 0.92A | 5nzyA-5m2mD:undetectable | 5nzyA-5m2mD:16.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nck | N-ACETYLMANNOSAMINEKINASE (Fusobacteriumnucleatum) |
PF00480(ROK) | 4 | THR A 173GLN A 240ILE A 238GLY A 236 | None | 1.01A | 5nzyA-5nckA:undetectable | 5nzyA-5nckA:21.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0x | PUTATIVE FERRICREDUCTASE (Cylindrospermumstagnale) |
PF08022(FAD_binding_8)PF08030(NAD_binding_6) | 4 | ASN A 439PHE A 438THR A 523GLY A 443 | PEG A 821 (-4.9A)NoneNoneNone | 0.69A | 5nzyA-5o0xA:2.9 | 5nzyA-5o0xA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tnx | ALCOHOLDEHYDROGENASEZINC-BINDING DOMAINPROTEIN (Burkholderiaambifaria) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ASN A 118PHE A 142THR A 180GLY A 177 | NoneNoneNoneCIT A 401 ( 4.8A) | 0.98A | 5nzyA-5tnxA:2.2 | 5nzyA-5tnxA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v0t | ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE(UDP-FORMING) (Paraburkholderiaxenovorans) |
PF00982(Glyco_transf_20) | 4 | PHE A 291ARG A 338ILE A 335GLY A 337 | None | 0.96A | 5nzyA-5v0tA:undetectable | 5nzyA-5v0tA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w6l | RTXREPEAT-CONTAININGCYTOTOXIN (Vibriovulnificus) |
no annotation | 4 | PHE A3696ARG A3629ILE A3632GLY A3628 | PHE A3696 ( 1.3A)ARG A3629 ( 0.6A)ILE A3632 ( 0.7A)GLY A3628 ( 0.0A) | 0.99A | 5nzyA-5w6lA:undetectable | 5nzyA-5w6lA:14.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ces | RAS-RELATEDGTP-BINDING PROTEINC (Homo sapiens) |
no annotation | 4 | ASN C 111PHE C 112THR C 137GLY C 138 | None | 0.99A | 5nzyA-6cesC:undetectable | 5nzyA-6cesC:11.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cv0 | SPIKE GLYCOPROTEIN (Aviancoronavirus) |
no annotation | 4 | PHE A 625ARG A 873ILE A 870GLY A 872 | None | 0.94A | 5nzyA-6cv0A:undetectable | 5nzyA-6cv0A:12.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f42 | DNA-DIRECTED RNAPOLYMERASE IIISUBUNIT RPC1 (Saccharomycescerevisiae) |
no annotation | 4 | ARG A1125THR A1120ILE A1126GLY A1122 | None | 0.90A | 5nzyA-6f42A:undetectable | 5nzyA-6f42A:11.92 |