SIMILAR PATTERNS OF AMINO ACIDS FOR 5NZX_A_9F2A1102
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a40 | PHOSPHATE-BINDINGPERIPLASMIC PROTEINPRECURSOR (Escherichiacoli) |
PF12849(PBP_like_2) | 5 | ASN A 48THR A 5GLN A 44ILE A 45GLY A 6 | None | 1.27A | 5nzxA-1a40A:0.0 | 5nzxA-1a40A:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ggm | GLYCINE--TRNA LIGASE (Thermusthermophilus) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon) | 4 | ASN A 227PHE A 228ARG A 366GLY A 367 | NoneNoneGAP A1550 ( 3.4A)None | 1.00A | 5nzxA-1ggmA:1.6 | 5nzxA-1ggmA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gz5 | ALPHA-TREHALOSE-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF00982(Glyco_transf_20) | 4 | ASN A 188ARG A 190THR A 220GLY A 183 | None | 0.82A | 5nzxA-1gz5A:0.9 | 5nzxA-1gz5A:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h0b | CELLULASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | ASN A 42PHE A 43THR A 89ILE A 62 | None | 0.99A | 5nzxA-1h0bA:undetectable | 5nzxA-1h0bA:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvm | 4-HYDROXY-2-OXOVALERATE ALDOLASE (Pseudomonas sp.CF600) |
PF00682(HMGL-like)PF07836(DmpG_comm) | 4 | THR A 15GLN A 272ILE A 23GLY A 19 | None | 0.95A | 5nzxA-1nvmA:0.0 | 5nzxA-1nvmA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o9b | HYPOTHETICALSHIKIMATE5-DEHYDROGENASE-LIKEPROTEIN YDIB (Escherichiacoli) |
PF08501(Shikimate_dh_N) | 4 | THR A 93GLN A 26ILE A 10GLY A 65 | None | 0.98A | 5nzxA-1o9bA:2.3 | 5nzxA-1o9bA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tp8 | AGGLUTININ ALPHACHAIN (Artocarpushirsutus) |
PF01419(Jacalin) | 4 | ASN A 105PHE A 104THR A 92GLY A 94 | None | 0.97A | 5nzxA-1tp8A:undetectable | 5nzxA-1tp8A:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vcl | HEMOLYTIC LECTINCEL-III (Cucumariaechinata) |
PF00652(Ricin_B_lectin) | 4 | PHE A 144GLN A 142ILE A 122GLY A 124 | NoneNoneNone CA A1002 (-4.3A) | 0.98A | 5nzxA-1vclA:0.0 | 5nzxA-1vclA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vki | HYPOTHETICAL PROTEINATU3699 (Agrobacteriumfabrum) |
PF04073(tRNA_edit) | 4 | PHE A 15THR A 107ILE A 112GLY A 110 | None | 0.93A | 5nzxA-1vkiA:0.5 | 5nzxA-1vkiA:18.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xfc | ALANINE RACEMASE (Mycobacteriumtuberculosis) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | ARG A 316THR A 274ILE A 317GLY A 315 | None | 1.01A | 5nzxA-1xfcA:undetectable | 5nzxA-1xfcA:20.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ypx | PUTATIVE VITAMIN-B12INDEPENDENTMETHIONINE SYNTHASEFAMILY PROTEIN (Listeriamonocytogenes) |
PF01717(Meth_synt_2) | 4 | ASN A 43THR A 18ILE A 41GLY A 20 | None | 0.98A | 5nzxA-1ypxA:2.5 | 5nzxA-1ypxA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ag1 | BENZALDEHYDE LYASE (Pseudomonasfluorescens) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | THR A 135GLN A 169ILE A 4GLY A 6 | None | 0.81A | 5nzxA-2ag1A:3.5 | 5nzxA-2ag1A:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bwa | ENDOGLUCANASE (Rhodothermusmarinus) |
PF01670(Glyco_hydro_12) | 4 | ASN A 42PHE A 43THR A 89ILE A 62 | None | 0.96A | 5nzxA-2bwaA:undetectable | 5nzxA-2bwaA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gjx | BETA-HEXOSAMINIDASEALPHA CHAIN (Homo sapiens) |
PF00728(Glyco_hydro_20)PF14845(Glycohydro_20b2) | 4 | ASN A 379THR A 387GLN A 357ILE A 356 | None | 0.93A | 5nzxA-2gjxA:undetectable | 5nzxA-2gjxA:23.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gk1 | BETA-HEXOSAMINIDASESUBUNIT ALPHA (Homo sapiens) |
no annotation | 4 | ASN I 379THR I 387GLN I 357ILE I 356 | None | 0.90A | 5nzxA-2gk1I:undetectable | 5nzxA-2gk1I:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gvs | CHEMOSENSORY PROTEINCSP-SG4 (Schistocercagregaria) |
PF03392(OS-D) | 4 | ASN A 19THR A 39ILE A 16GLY A 42 | None | 0.92A | 5nzxA-2gvsA:undetectable | 5nzxA-2gvsA:16.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jch | PENICILLIN-BINDINGPROTEIN 1B (Streptococcuspneumoniae) |
PF00905(Transpeptidase)PF00912(Transgly) | 4 | THR A 667GLN A 705ILE A 711GLY A 713 | None | 0.94A | 5nzxA-2jchA:undetectable | 5nzxA-2jchA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jzl | CYANOVIRIN-N HOMOLOG (Neurosporacrassa) |
PF08881(CVNH) | 4 | PHE A 107GLN A 41ILE A 42GLY A 54 | None | 1.00A | 5nzxA-2jzlA:undetectable | 5nzxA-2jzlA:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lfe | E3 UBIQUITIN-PROTEINLIGASE HECW2 (Homo sapiens) |
PF16562(HECW_N) | 4 | ASN A 110THR A 116ILE A 121GLY A 119 | None | 0.91A | 5nzxA-2lfeA:undetectable | 5nzxA-2lfeA:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2op6 | HEAT SHOCK 70 KDAPROTEIN D (Caenorhabditiselegans) |
PF00012(HSP70) | 4 | ASN A 483PHE A 484ILE A 467GLY A 427 | None | 0.99A | 5nzxA-2op6A:undetectable | 5nzxA-2op6A:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2or2 | 1-PHOSPHATIDYLINOSITOL PHOSPHODIESTERASE (Bacillusthuringiensis) |
PF00388(PI-PLC-X) | 4 | PHE A 55ARG A 69ILE A 68GLY A 70 | None | 0.99A | 5nzxA-2or2A:undetectable | 5nzxA-2or2A:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pg6 | CYTOCHROME P450 2A6 (Homo sapiens) |
PF00067(p450) | 4 | PHE A 238THR A 214GLN A 234GLY A 217 | None | 0.96A | 5nzxA-2pg6A:undetectable | 5nzxA-2pg6A:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vut | NITROGEN METABOLITEREPRESSION REGULATORNMRA (Aspergillusnidulans) |
PF05368(NmrA) | 4 | PHE A 181THR A 219ILE A 152GLY A 151 | NoneNoneNAD A1353 (-4.3A)NAD A1353 (-4.7A) | 0.93A | 5nzxA-2vutA:undetectable | 5nzxA-2vutA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w38 | SIALIDASE (Pseudomonasaeruginosa) |
PF13088(BNR_2) | 4 | PHE A 55ARG A 89ILE A 90GLY A 88 | None | 0.97A | 5nzxA-2w38A:undetectable | 5nzxA-2w38A:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x2i | ALPHA-1,4-GLUCANLYASE ISOZYME 1 (Gracilariopsislemaneiformis) |
PF01055(Glyco_hydro_31) | 4 | ARG A 201THR A 229GLN A 207GLY A 209 | None | 0.93A | 5nzxA-2x2iA:undetectable | 5nzxA-2x2iA:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xrc | HUMAN COMPLEMENTFACTOR I (Homo sapiens) |
PF00057(Ldl_recept_a)PF00089(Trypsin)PF00530(SRCR) | 4 | ASN A 159THR A 185GLN A 189GLY A 187 | NAG A 659 (-1.9A)NoneNoneNone | 0.94A | 5nzxA-2xrcA:undetectable | 5nzxA-2xrcA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z22 | PERIPLASMICPHOSPHATE-BINDINGPROTEIN (Yersinia pestis) |
no annotation | 5 | ASN X 48THR X 5GLN X 44ILE X 45GLY X 6 | None | 1.26A | 5nzxA-2z22X:undetectable | 5nzxA-2z22X:24.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z4d | 26S PROTEASOMEREGULATORY SUBUNITRPN13 (Saccharomycescerevisiae) |
PF04683(Proteasom_Rpn13) | 4 | ARG A 51THR A 53ILE A 33GLY A 31 | None | 0.83A | 5nzxA-2z4dA:undetectable | 5nzxA-2z4dA:15.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zym | SOLUTE-BINDINGPROTEIN (Thermoactinomycesvulgaris) |
PF13416(SBP_bac_8) | 4 | PHE A 189THR A 90ILE A 353GLY A 86 | None | 0.88A | 5nzxA-2zymA:undetectable | 5nzxA-2zymA:22.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5a | HEMOGLOBIN V (Tokunagayusurikaakamusi) |
PF00042(Globin) | 4 | PHE A 46ARG A 69ILE A 66GLY A 68 | HEM A 153 (-3.9A)HEM A 153 (-3.6A)NoneNone | 0.97A | 5nzxA-3a5aA:undetectable | 5nzxA-3a5aA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abb | CYTOCHROME P450HYDROXYLASE (Streptomycesavermitilis) |
PF00067(p450) | 4 | ASN A 357PHE A 113THR A 248GLY A 244 | NoneNoneHEM A1430 (-3.8A)HEM A1430 (-3.2A) | 0.99A | 5nzxA-3abbA:undetectable | 5nzxA-3abbA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abi | PUTATIVEUNCHARACTERIZEDPROTEIN PH1688 (Pyrococcushorikoshii) |
PF03435(Sacchrp_dh_NADP)PF16653(Sacchrp_dh_C) | 4 | ARG A 328THR A 331ILE A 324GLY A 326 | None | 0.99A | 5nzxA-3abiA:undetectable | 5nzxA-3abiA:23.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayr | ENDOGLUCANASE (Piromycesrhizinflatus) |
PF00150(Cellulase) | 4 | PHE A 62ARG A 346GLN A 343GLY A 345 | None | 0.95A | 5nzxA-3ayrA:1.5 | 5nzxA-3ayrA:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0k | UPF0064 PROTEIN YCCW (Escherichiacoli) |
PF10672(Methyltrans_SAM) | 4 | ASN A 322GLN A 327ILE A 326GLY A 361 | None | 0.89A | 5nzxA-3c0kA:undetectable | 5nzxA-3c0kA:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cer | POSSIBLEEXOPOLYPHOSPHATASE-LIKE PROTEIN (Bifidobacteriumlongum) |
PF02541(Ppx-GppA) | 4 | PHE A 78THR A 95ILE A 28GLY A 24 | NoneSO4 A 344 ( 3.5A)NoneSO4 A 344 (-3.3A) | 0.97A | 5nzxA-3cerA:2.1 | 5nzxA-3cerA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cm1 | SSGA-LIKESPORULATION-SPECIFICCELL DIVISIONPROTEIN (Thermobifidafusca) |
PF04686(SsgA) | 4 | ASN A 88ARG A 75ILE A 76GLY A 70 | None | 0.99A | 5nzxA-3cm1A:undetectable | 5nzxA-3cm1A:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A1249PHE A1255THR A 74GLY A 71 | NoneNoneADP A 502 (-4.0A)ADP A 502 (-3.3A) | 0.94A | 5nzxA-3cmtA:2.6 | 5nzxA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A2249PHE A2255THR A1074GLY A1071 | NoneNoneADP A1502 (-3.9A)ADP A1502 (-3.4A) | 0.95A | 5nzxA-3cmtA:2.6 | 5nzxA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A3249PHE A3255THR A2074GLY A2071 | NoneNoneADP A2502 (-3.8A)ADP A2502 (-3.4A) | 0.94A | 5nzxA-3cmtA:2.6 | 5nzxA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmt | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A4249PHE A4255THR A3074GLY A3071 | NoneNoneADP A3502 (-3.7A)ADP A3502 (-3.4A) | 0.95A | 5nzxA-3cmtA:2.6 | 5nzxA-3cmtA:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A1249PHE A1255THR A 74GLY A 71 | NoneNoneADP A 502 (-3.9A)ADP A 502 (-3.0A) | 0.95A | 5nzxA-3cmuA:undetectable | 5nzxA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A2249PHE A2255THR A1074GLY A1071 | NoneNoneADP A1502 (-3.5A)ADP A1502 (-2.8A) | 0.97A | 5nzxA-3cmuA:undetectable | 5nzxA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A4249PHE A4255THR A3074GLY A3071 | NoneNoneADP A3502 (-3.7A)ADP A3502 (-2.7A) | 0.96A | 5nzxA-3cmuA:undetectable | 5nzxA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cmu | PROTEIN RECA (Escherichiacoli) |
PF00154(RecA) | 4 | ASN A5249PHE A5255THR A4074GLY A4071 | NoneNoneADP A4502 (-3.8A)ADP A4502 (-2.8A) | 0.97A | 5nzxA-3cmuA:undetectable | 5nzxA-3cmuA:9.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3x | BIPA (Vibrioparahaemolyticus) |
PF00679(EFG_C) | 4 | PHE A 295ARG A 233ILE A 250GLY A 232 | None | 0.88A | 5nzxA-3e3xA:undetectable | 5nzxA-3e3xA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fez | UNCHARACTERIZEDFERREDOXIN FOLDPROTEIN RELATED TOANTIBIOTICBIOSYNTHESISMONOOXYGENASES (Listeriamonocytogenes) |
no annotation | 4 | ASN A 20THR A 7GLN A 48GLY A 50 | None | 0.96A | 5nzxA-3fezA:undetectable | 5nzxA-3fezA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ico | 6-PHOSPHOGLUCONOLACTONASE (Mycobacteriumtuberculosis) |
PF01182(Glucosamine_iso) | 4 | THR A 233GLN A 192ILE A 191GLY A 229 | None | 0.90A | 5nzxA-3icoA:undetectable | 5nzxA-3icoA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3im8 | MALONYL ACYL CARRIERPROTEIN TRANSACYLASE (Streptococcuspneumoniae) |
PF00698(Acyl_transf_1) | 4 | ASN A 268PHE A 269GLN A 262ILE A 266 | None | 0.91A | 5nzxA-3im8A:undetectable | 5nzxA-3im8A:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju8 | SUCCINYLGLUTAMICSEMIALDEHYDEDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00171(Aldedh) | 4 | ASN A 197THR A 205GLN A 200GLY A 35 | None | 0.93A | 5nzxA-3ju8A:undetectable | 5nzxA-3ju8A:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lnb | N-ACETYLTRANSFERASEFAMILY PROTEIN (Bacillusanthracis) |
PF00797(Acetyltransf_2) | 4 | PHE A 191ARG A 150ILE A 151GLY A 139 | None | 0.92A | 5nzxA-3lnbA:undetectable | 5nzxA-3lnbA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m9u | FARNESYL-DIPHOSPHATESYNTHASE (Lactobacillusbrevis) |
PF00348(polyprenyl_synt) | 4 | THR A 55GLN A 193ILE A 197GLY A 195 | None | 0.87A | 5nzxA-3m9uA:undetectable | 5nzxA-3m9uA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mep | UNCHARACTERIZEDPROTEIN ECA2234 (Pectobacteriumatrosepticum) |
PF07081(DUF1349) | 4 | PHE A 73THR A 118ILE A 96GLY A 106 | None | 0.88A | 5nzxA-3mepA:undetectable | 5nzxA-3mepA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8a | UNCHARACTERIZEDPROTEIN (Staphylococcusaureus) |
PF13468(Glyoxalase_3) | 4 | PHE A 40ARG A 264ILE A 263GLY A 265 | None | 1.00A | 5nzxA-3p8aA:undetectable | 5nzxA-3p8aA:20.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p8s | JACALIN (Artocarpusheterophyllus) |
PF01419(Jacalin) | 4 | ASN A 129PHE A 128THR A 116GLY A 118 | None | 0.99A | 5nzxA-3p8sA:undetectable | 5nzxA-3p8sA:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rc3 | ATP-DEPENDENT RNAHELICASE SUPV3L1,MITOCHONDRIAL (Homo sapiens) |
PF00271(Helicase_C)PF12513(SUV3_C) | 4 | PHE A 411ARG A 473ILE A 435GLY A 472 | NoneANP A 801 (-3.0A)NoneNone | 0.97A | 5nzxA-3rc3A:3.6 | 5nzxA-3rc3A:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rh9 | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE(NAD(P)(+)) (Marinobacterhydrocarbonoclasticus) |
PF00171(Aldedh) | 4 | ARG A 238THR A 234ILE A 241GLY A 237 | None | 0.95A | 5nzxA-3rh9A:undetectable | 5nzxA-3rh9A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tx2 | PROBABLE6-PHOSPHOGLUCONOLACTONASE (Mycobacteroidesabscessus) |
PF01182(Glucosamine_iso) | 4 | THR A 234GLN A 193ILE A 192GLY A 230 | None | 0.93A | 5nzxA-3tx2A:undetectable | 5nzxA-3tx2A:22.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgj | TYROSYL-TRNASYNTHETASE, PUTATIVE (Plasmodiumfalciparum) |
PF00579(tRNA-synt_1b) | 4 | ASN A 364ARG A 68ILE A 366GLY A 67 | None | 1.00A | 5nzxA-3vgjA:undetectable | 5nzxA-3vgjA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vs8 | TYPE III POLYKETIDESYNTHASE (Azotobactervinelandii) |
PF02797(Chal_sti_synt_C) | 4 | ASN A 365PHE A 362THR A 29ILE A 74 | None | 0.99A | 5nzxA-3vs8A:undetectable | 5nzxA-3vs8A:20.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a4z | ANTIVIRAL HELICASESKI2 (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C)PF08148(DSHCT)PF13234(rRNA_proc-arch) | 4 | ASN A 450THR A 798GLN A 759GLY A 755 | None | 0.93A | 5nzxA-4a4zA:undetectable | 5nzxA-4a4zA:16.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8s | ADP-DEPENDENTGLUCOKINASE (Thermococcuslitoralis) |
PF04587(ADP_PFK_GK) | 4 | ASN A 70ARG A 87ILE A 67GLY A 84 | None | 0.98A | 5nzxA-4b8sA:1.2 | 5nzxA-4b8sA:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e1e | FARNESYLPYROPHOSPHATESYNTHASE (Trypanosomacruzi) |
PF00348(polyprenyl_synt) | 4 | PHE A 321THR A 208GLN A 249GLY A 243 | NoneIPE A 405 ( 4.6A)NoneNone | 0.93A | 5nzxA-4e1eA:undetectable | 5nzxA-4e1eA:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4epa | PESTICIN RECEPTOR (Yersinia pestis) |
PF00593(TonB_dep_Rec)PF07715(Plug) | 4 | PHE A 581ARG A 549GLN A 589GLY A 577 | None | 0.93A | 5nzxA-4epaA:undetectable | 5nzxA-4epaA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ewt | PEPTIDASE,M20/M25/M40 FAMILY (Staphylococcusaureus) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ASN A 367PHE A 366THR A 171ILE A 368GLY A 350 | None | 1.48A | 5nzxA-4ewtA:undetectable | 5nzxA-4ewtA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hva | CASPASE-6 (Homo sapiens) |
PF00656(Peptidase_C14) | 4 | PHE A 55ARG A 65THR A 222GLY A 66 | None | 0.89A | 5nzxA-4hvaA:undetectable | 5nzxA-4hvaA:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j05 | PHOSPHATETRANSPORTER (Serendipitaindica) |
PF00083(Sugar_tr) | 4 | ASN A 431PHE A 426THR A 496GLY A 492 | PO4 A 600 (-3.1A)NoneNoneNone | 0.89A | 5nzxA-4j05A:undetectable | 5nzxA-4j05A:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4je3 | CENTRAL KINETOCHORESUBUNIT CHL4CENTRAL KINETOCHORESUBUNIT IML3 (Saccharomycescerevisiae) |
PF05238(CENP-N)no annotation | 4 | ASN B 405THR A 153ILE B 409GLY B 412 | None | 0.99A | 5nzxA-4je3B:undetectable | 5nzxA-4je3B:15.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4juu | EPIMERASE (Xanthomonascampestris) |
PF05544(Pro_racemase) | 4 | PHE A 271ARG A 97ILE A 93GLY A 94 | None | 0.91A | 5nzxA-4juuA:undetectable | 5nzxA-4juuA:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jzx | FARNESYLPYROPHOSPHATESYNTHASE (Leishmaniamajor) |
PF00348(polyprenyl_synt) | 4 | PHE A 321THR A 208GLN A 249GLY A 243 | NoneIPE A 401 ( 3.4A)NoneNone | 0.95A | 5nzxA-4jzxA:undetectable | 5nzxA-4jzxA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k1c | VACUOLAR CALCIUM IONTRANSPORTER (Saccharomycescerevisiae) |
PF01699(Na_Ca_ex) | 4 | ASN A 80THR A 261ILE A 256GLY A 259 | None | 0.99A | 5nzxA-4k1cA:undetectable | 5nzxA-4k1cA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ktp | GLYCOSIDE HYDROLASEFAMILY 65 CENTRALCATALYTIC ([Bacillus]selenitireducens) |
PF03632(Glyco_hydro_65m)PF03633(Glyco_hydro_65C)PF03636(Glyco_hydro_65N) | 4 | PHE A 666THR A 45ILE A 27GLY A 30 | None | 0.93A | 5nzxA-4ktpA:undetectable | 5nzxA-4ktpA:17.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l8j | PUTATIVE EFFLUXTRANSPORTER (Bacteroideseggerthii) |
PF16576(HlyD_D23) | 4 | ASN A 69GLN A 66ILE A 67GLY A 65 | None | 0.90A | 5nzxA-4l8jA:undetectable | 5nzxA-4l8jA:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o4f | INOSITOLHEXAKISPHOSPHATEKINASE (Entamoebahistolytica) |
PF03770(IPK) | 4 | PHE A 232THR A 61ILE A 64GLY A 62 | None | 0.91A | 5nzxA-4o4fA:undetectable | 5nzxA-4o4fA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4okm | TERPENE SYNTHASEMETAL-BINDINGDOMAIN-CONTAININGPROTEIN (Streptomycespristinaespiralis) |
no annotation | 4 | PHE A 272ARG A 299ILE A 298GLY A 300 | None | 0.84A | 5nzxA-4okmA:undetectable | 5nzxA-4okmA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj3 | INTRON-BINDINGPROTEIN AQUARIUS (Homo sapiens) |
PF13086(AAA_11)PF13087(AAA_12)PF16399(Aquarius_N) | 4 | PHE A 802THR A 819ILE A 810GLY A 813 | None | 1.00A | 5nzxA-4pj3A:3.7 | 5nzxA-4pj3A:12.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 5 | ASN A 938PHE A 939THR A 962ILE A 986GLY A 988 | None | 0.58A | 5nzxA-5ahrA:48.0 | 5nzxA-5ahrA:99.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ahr | DNA CROSS-LINKREPAIR 1A PROTEIN (Homo sapiens) |
PF07522(DRMBL)PF12706(Lactamase_B_2) | 5 | PHE A 939THR A 962GLN A 979ILE A 986GLY A 988 | None | 1.03A | 5nzxA-5ahrA:48.0 | 5nzxA-5ahrA:99.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5chc | DMSO REDUCTASEFAMILY TYPE IIENZYME,MOLYBDOPTERINSUBUNIT (Azospira oryzae) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | PHE A 214ARG A 208THR A 37GLY A 38 | NoneMGD A1003 ( 3.6A)MGD A1003 ( 4.8A)SF4 A1001 ( 3.8A) | 1.00A | 5nzxA-5chcA:undetectable | 5nzxA-5chcA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cnx | AMINOPEPTIDASE YPDF (Escherichiacoli) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 4 | PHE A 304ARG A 261ILE A 260GLY A 344 | None | 0.98A | 5nzxA-5cnxA:undetectable | 5nzxA-5cnxA:20.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eny | POLYKETIDE SYNTHASEPKSL (Bacillussubtilis) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | ASN A 376PHE A 379THR A 369GLY A 336 | None | 0.76A | 5nzxA-5enyA:undetectable | 5nzxA-5enyA:18.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fma | NEUROGENIC LOCUSNOTCH HOMOLOGPROTEIN 1 (Homo sapiens) |
PF00008(EGF)PF07645(EGF_CA) | 4 | ASN A 264THR A 293GLN A 290GLY A 289 | None | 1.00A | 5nzxA-5fmaA:undetectable | 5nzxA-5fmaA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i2u | CELLULASE (soil metagenome) |
PF00150(Cellulase) | 4 | PHE A 123THR A 200ILE A 140GLY A 175 | None | 0.98A | 5nzxA-5i2uA:undetectable | 5nzxA-5i2uA:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kq1 | MRNA DECAPPINGCOMPLEX SUBUNIT 2 (Schizosaccharomycespombe) |
PF00293(NUDIX)PF05026(DCP2) | 4 | PHE B 225ARG B 167ILE B 166GLY B 168 | None | 0.73A | 5nzxA-5kq1B:undetectable | 5nzxA-5kq1B:21.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l9s | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (MANNOPINE) (Agrobacteriumfabrum) |
PF13416(SBP_bac_8) | 4 | ASN A 178PHE A 179GLN A 242GLY A 241 | None | 0.97A | 5nzxA-5l9sA:undetectable | 5nzxA-5l9sA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5map | DTPA (Streptomyceslividans) |
PF04261(Dyp_perox) | 4 | ASN A 231ARG A 232THR A 237GLY A 235 | None | 0.98A | 5nzxA-5mapA:undetectable | 5nzxA-5mapA:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mnw | GUANYLATE CYCLASESOLUBLE SUBUNITBETA-1 (Homo sapiens) |
no annotation | 5 | PHE A 75THR A 160GLN A 156ILE A 157GLY A 159 | None | 1.40A | 5nzxA-5mnwA:undetectable | 5nzxA-5mnwA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n8o | DNA HELICASE I (Escherichiacoli) |
PF07057(TraI)PF08751(TrwC)PF13604(AAA_30) | 4 | ASN A1268ARG A1270ILE A1269GLY A1272 | None | 0.95A | 5nzxA-5n8oA:undetectable | 5nzxA-5n8oA:10.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nfr | MALATE DEHYDROGENASE (Plasmodiumfalciparum) |
no annotation | 5 | PHE A 230THR A 76GLN A 11ILE A 15GLY A 13 | None | 1.32A | 5nzxA-5nfrA:undetectable | 5nzxA-5nfrA:15.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nx7 | PENTALENENE SYNTHASE (Streptomycesclavuligerus) |
no annotation | 4 | PHE A 267ARG A 303ILE A 302GLY A 304 | None | 0.89A | 5nzxA-5nx7A:undetectable | 5nzxA-5nx7A:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o0x | PUTATIVE FERRICREDUCTASE (Cylindrospermumstagnale) |
PF08022(FAD_binding_8)PF08030(NAD_binding_6) | 4 | ASN A 439PHE A 438THR A 523GLY A 443 | PEG A 821 (-4.9A)NoneNoneNone | 0.63A | 5nzxA-5o0xA:undetectable | 5nzxA-5o0xA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5odr | HETERODISULFIDEREDUCTASE, SUBUNIT A (Methanothermococcusthermolithotrophicus) |
PF07992(Pyr_redox_2)PF13187(Fer4_9) | 4 | THR A 653GLN A 645ILE A 646GLY A 648 | None | 0.79A | 5nzxA-5odrA:undetectable | 5nzxA-5odrA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tnx | ALCOHOLDEHYDROGENASEZINC-BINDING DOMAINPROTEIN (Burkholderiaambifaria) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | ASN A 118PHE A 142THR A 180GLY A 177 | NoneNoneNoneCIT A 401 ( 4.8A) | 0.97A | 5nzxA-5tnxA:2.5 | 5nzxA-5tnxA:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u8s | CELL DIVISIONCONTROL PROTEIN 45 (Saccharomycescerevisiae) |
PF02724(CDC45) | 4 | ASN E 342ARG E 547THR E 429ILE E 282 | None | 0.92A | 5nzxA-5u8sE:2.3 | 5nzxA-5u8sE:19.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w7c | ACYLOXYACYLHYDROLASE (Homo sapiens) |
no annotation | 4 | PHE C 499GLN C 553ILE C 554GLY C 556 | None | 0.97A | 5nzxA-5w7cC:undetectable | 5nzxA-5w7cC:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wvm | MALTOSE-BINDINGPERIPLASMICPROTEIN,TWO-COMPONENT SYSTEM SENSORKINASE (Escherichiacoli;Serratiamarcescens) |
no annotation | 4 | PHE A 494ARG A 375ILE A 378GLY A 376 | None | 0.89A | 5nzxA-5wvmA:undetectable | 5nzxA-5wvmA:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | UNCHARACTERIZEDPROTEIN (Trichomonasvaginalis) |
PF00163(Ribosomal_S4)PF01479(S4) | 4 | ASN J 63ARG J 67ILE J 68GLY J 71 | None | 0.92A | 5nzxA-5xyiJ:undetectable | 5nzxA-5xyiJ:14.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yz0 | SERINE/THREONINE-PROTEIN KINASE ATR (Homo sapiens) |
no annotation | 4 | ASN A1668THR A2528ILE A1662GLY A2524 | None | 1.00A | 5nzxA-5yz0A:undetectable | 5nzxA-5yz0A:12.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a31 | PEPTIDYL-TRNAHYDROLASE (Acinetobacterbaumannii) |
no annotation | 4 | ASN A 54ARG A 52ILE A 38GLY A 51 | None | 0.96A | 5nzxA-6a31A:3.3 | 5nzxA-6a31A:11.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2j | RNAP2 (Escherichiavirus N4) |
no annotation | 4 | PHE B 335ARG B 355GLN B 357ILE B 354 | None | 0.96A | 5nzxA-6c2jB:undetectable | 5nzxA-6c2jB:11.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ces | RAS-RELATEDGTP-BINDING PROTEINC (Homo sapiens) |
no annotation | 5 | ASN C 111PHE C 112ARG C 63THR C 137GLY C 138 | None | 1.00A | 5nzxA-6cesC:undetectable | 5nzxA-6cesC:11.29 |