SIMILAR PATTERNS OF AMINO ACIDS FOR 5NY7_A_NCAA303_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1adr P22 C2 REPRESSOR

(Salmonella
virus P22) 		PF01381
(HTH_3) 		4 ARG A  11
GLY A   7
GLU A  39
SER A  36
 None
 1.04A 5ny7A-1adrA:
undetectable		 5ny7A-1adrA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkp PHYTASE

(Escherichia
coli) 		PF00328
(His_Phos_2) 		4 GLY A 373
PRO A 372
GLU A 374
SER A 351
 None
 1.13A 5ny7A-1dkpA:
undetectable		 5ny7A-1dkpA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 ARG A 424
GLY A 325
GLU A 267
SER A 271
 None
 1.03A 5ny7A-1ezvA:
undetectable		 5ny7A-1ezvA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2u DEFENSIN HELIOMICIN

(Heliothis
virescens) 		no annotation 4 ARG A  25
GLY A   5
THR A  15
GLU A  21
 None
 0.85A 5ny7A-1i2uA:
undetectable		 5ny7A-1i2uA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i36 CONSERVED
HYPOTHETICAL PROTEIN
MTH1747

(Methanothermobacter
thermautotrophicus) 		PF03807
(F420_oxidored)
PF09130
(DUF1932) 		4 ARG A 117
GLY A 120
THR A  14
GLU A  10
 None
None
None
NAP  A1350 (-4.3A)
 0.74A 5ny7A-1i36A:
undetectable		 5ny7A-1i36A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kij DNA GYRASE SUBUNIT B

(Thermus
thermophilus) 		PF00204
(DNA_gyraseB)
PF02518
(HATPase_c) 		4 ARG A  75
PRO A  78
THR A 166
GLU A  49
 NOV  A 400 (-3.4A)
NOV  A 400 (-4.4A)
NOV  A 400 (-3.3A)
NOV  A 400 (-3.6A)
 1.05A 5ny7A-1kijA:
undetectable		 5ny7A-1kijA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		4 ARG A 255
GLY A 253
THR A 271
GLU A 272
 None
 1.02A 5ny7A-1m9qA:
undetectable		 5ny7A-1m9qA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1npe NIDOGEN

(Mus musculus) 		PF00058
(Ldl_recept_b) 		4 GLY A1038
THR A1008
GLU A 994
SER A1010
 None
 0.99A 5ny7A-1npeA:
undetectable		 5ny7A-1npeA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p8r ARGINASE 1

(Rattus
norvegicus) 		PF00491
(Arginase) 		4 GLY A 185
PRO A 184
THR A 134
SER A 136
 None
None
None
S2C  A 551 ( 3.7A)
 1.01A 5ny7A-1p8rA:
1.9		 5ny7A-1p8rA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pto PERTUSSIS TOXIN

(Bordetella
pertussis) 		PF02918
(Pertussis_S2S3)
PF03440
(APT) 		4 ARG C 141
GLY C 140
GLU C 170
SER C 168
 None
 0.97A 5ny7A-1ptoC:
undetectable		 5ny7A-1ptoC:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaa PROTEIN
(ATP-DEPENDENT DNA
HELICASE REP.)

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		4 ARG A 350
GLY A 576
GLU A 592
SER A 583
 None
 0.95A 5ny7A-1uaaA:
undetectable		 5ny7A-1uaaA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v2d GLUTAMINE
AMINOTRANSFERASE

(Thermus
thermophilus) 		PF00155
(Aminotran_1_2) 		4 ARG A 205
PRO A 203
THR A 160
GLU A 192
 None
 1.13A 5ny7A-1v2dA:
undetectable		 5ny7A-1v2dA:
27.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vli SPORE COAT
POLYSACCHARIDE
BIOSYNTHESIS PROTEIN
SPSE

(Bacillus
subtilis) 		PF03102
(NeuB)
PF08666
(SAF) 		4 ARG A 265
GLY A 263
THR A 267
GLU A 268
 None
 0.92A 5ny7A-1vliA:
2.3		 5ny7A-1vliA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zo1 TRANSLATION
INITIATION FACTOR 2

(Escherichia
coli) 		PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
PF11987
(IF-2) 		4 GLY I 457
PRO I 458
GLU I 455
SER I 468
 None
 0.71A 5ny7A-1zo1I:
undetectable		 5ny7A-1zo1I:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cpc KIAA0657 PROTEIN

(Homo sapiens) 		PF13927
(Ig_3) 		4 GLY A  50
THR A  47
GLU A  86
SER A  91
 None
 1.11A 5ny7A-2cpcA:
undetectable		 5ny7A-2cpcA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2egw UPF0088 PROTEIN
AQ_165

(Aquifex
aeolicus) 		PF04452
(Methyltrans_RNA) 		4 GLY A 185
PRO A 186
GLU A 194
SER A 191
 SAH  A 300 ( 3.6A)
None
None
None
 0.78A 5ny7A-2egwA:
undetectable		 5ny7A-2egwA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fsq ATU0111 PROTEIN

(Agrobacterium
fabrum) 		PF08975
(2H-phosphodiest) 		4 ARG A  28
GLY A  26
GLU A  38
SER A  92
 None
 0.82A 5ny7A-2fsqA:
undetectable		 5ny7A-2fsqA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 ARG A 257
GLY A 256
THR A 110
GLU A 111
 None
 0.91A 5ny7A-2gmhA:
undetectable		 5ny7A-2gmhA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hpi DNA POLYMERASE III
ALPHA SUBUNIT

(Thermus
aquaticus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		4 ARG A 909
GLY A 913
PRO A 914
GLU A 910
 None
 1.09A 5ny7A-2hpiA:
undetectable		 5ny7A-2hpiA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j59 RHO-GTPASE
ACTIVATING PROTEIN
10

(Homo sapiens) 		PF15410
(PH_9) 		4 ARG M1009
THR M1002
GLU M1001
SER M1000
 None
SO4  M2064 (-3.5A)
None
None
 1.08A 5ny7A-2j59M:
undetectable		 5ny7A-2j59M:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2q FORMYLTETRAHYDROFOLA
TE DEHYDROGENASE

(Rattus
norvegicus) 		PF00171
(Aldedh) 		4 ARG A 781
GLY A 747
PRO A 748
THR A 744
 SO4  A3024 (-2.9A)
None
None
None
 0.87A 5ny7A-2o2qA:
undetectable		 5ny7A-2o2qA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2owi REGULATOR OF
G-PROTEIN SIGNALING
18

(Homo sapiens) 		PF00615
(RGS) 		4 ARG A 119
THR A  34
GLU A  35
SER A  37
 None
 1.04A 5ny7A-2owiA:
undetectable		 5ny7A-2owiA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p4g HYPOTHETICAL PROTEIN

(Corynebacterium
diphtheriae) 		PF01872
(RibD_C) 		4 GLY A 195
PRO A 196
THR A  81
SER A  53
 EDO  A 272 ( 3.1A)
EDO  A 272 ( 3.8A)
EDO  A 284 ( 3.5A)
EDO  A 280 ( 3.1A)
 1.01A 5ny7A-2p4gA:
undetectable		 5ny7A-2p4gA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paj PUTATIVE
CYTOSINE/GUANINE
DEAMINASE

(unidentified) 		PF01979
(Amidohydro_1) 		4 GLY A  57
PRO A  56
GLU A  58
SER A  11
 None
 1.13A 5ny7A-2pajA:
4.0		 5ny7A-2pajA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r9q 2'-DEOXYCYTIDINE
5'-TRIPHOSPHATE
DEAMINASE

(Agrobacterium
fabrum) 		PF06559
(DCD) 		4 ARG A  47
GLY A  49
GLU A  99
SER A  30
 None
 0.98A 5ny7A-2r9qA:
undetectable		 5ny7A-2r9qA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wrz L-ARABINOSE-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00532
(Peripla_BP_1) 		4 ARG A 214
GLY A 212
THR A 216
GLU A 217
 None
 0.86A 5ny7A-2wrzA:
undetectable		 5ny7A-2wrzA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y2w ARABINOFURANOSIDASE

(Bifidobacterium
longum) 		PF06964
(Alpha-L-AF_C) 		4 ARG A  62
PRO A  61
THR A 106
GLU A 162
 None
 1.08A 5ny7A-2y2wA:
undetectable		 5ny7A-2y2wA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn0 TRANSCRIPTION FACTOR
TAU 55 KDA SUBUNIT

(Saccharomyces
cerevisiae) 		PF00300
(His_Phos_1) 		4 ARG A 198
GLY A 242
THR A 244
GLU A 251
 None
 1.11A 5ny7A-2yn0A:
undetectable		 5ny7A-2yn0A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ynk WZI

(Escherichia
coli) 		PF14052
(Caps_assemb_Wzi) 		4 ARG A  43
GLY A  44
GLU A  74
SER A  70
 None
 1.10A 5ny7A-2ynkA:
undetectable		 5ny7A-2ynkA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z4r CHROMOSOMAL
REPLICATION
INITIATOR PROTEIN
DNAA

(Thermotoga
maritima) 		PF00308
(Bac_DnaA) 		4 GLY A 110
PRO A 111
THR A 267
GLU A 266
 None
 0.94A 5ny7A-2z4rA:
undetectable		 5ny7A-2z4rA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al9 PLEXIN-A2

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI) 		4 ARG A 205
GLY A 180
GLU A 123
SER A 122
 None
 0.87A 5ny7A-3al9A:
undetectable		 5ny7A-3al9A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aqg ZYMOGEN GRANULE
PROTEIN 16 HOMOLOG B

(Homo sapiens) 		PF01419
(Jacalin) 		4 ARG A  78
GLY A  76
THR A 112
GLU A 110
 PO4  A   2 (-3.3A)
None
None
PO4  A   2 (-3.3A)
 1.11A 5ny7A-3aqgA:
undetectable		 5ny7A-3aqgA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3atg GLUCANASE

(Cellulosimicrobium
cellulans) 		PF00722
(Glyco_hydro_16) 		4 ARG A  85
GLY A 182
THR A 166
GLU A  87
 None
 1.10A 5ny7A-3atgA:
undetectable		 5ny7A-3atgA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c8u FRUCTOKINASE

(Ruegeria sp.
TM1040) 		no annotation 4 ARG A  75
GLY A  77
THR A  81
GLU A  80
 None
 1.11A 5ny7A-3c8uA:
undetectable		 5ny7A-3c8uA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eeh PUTATIVE LIGHT AND
REDOX SENSING
HISTIDINE KINASE

(Haloarcula
marismortui) 		PF08447
(PAS_3) 		4 ARG A  98
GLY A  46
THR A  93
GLU A  94
 None
 0.90A 5ny7A-3eehA:
undetectable		 5ny7A-3eehA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3en8 UNCHARACTERIZED
NTF-2 LIKE PROTEIN

(Paraburkholderia
xenovorans) 		PF12680
(SnoaL_2) 		4 ARG A  54
GLY A  59
GLU A  25
SER A  17
 None
 1.01A 5ny7A-3en8A:
undetectable		 5ny7A-3en8A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fv5 DNA TOPOISOMERASE 4
SUBUNIT B

(Escherichia
coli) 		PF02518
(HATPase_c) 		4 ARG A  72
PRO A  75
THR A 163
GLU A  46
 1EU  A   2 (-3.3A)
1EU  A   2 (-4.2A)
1EU  A   2 (-3.7A)
1EU  A   2 (-3.4A)
 1.07A 5ny7A-3fv5A:
2.0		 5ny7A-3fv5A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kw2 PROBABLE R-RNA
METHYLTRANSFERASE

(Porphyromonas
gingivalis) 		PF04452
(Methyltrans_RNA) 		4 GLY A 196
PRO A 197
GLU A 205
SER A 202
 ADN  A 300 (-3.2A)
ADN  A 300 (-4.9A)
None
None
 0.97A 5ny7A-3kw2A:
2.0		 5ny7A-3kw2A:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l51 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
4

(Mus musculus) 		PF06470
(SMC_hinge) 		4 GLY B 612
PRO B 611
THR B 648
GLU B 651
 None
 1.04A 5ny7A-3l51B:
undetectable		 5ny7A-3l51B:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lws AROMATIC AMINO ACID
BETA-ELIMINATING
LYASE/THREONINE
ALDOLASE

(Exiguobacterium
sibiricum) 		PF01212
(Beta_elim_lyase) 		4 ARG A 145
GLY A 148
GLU A 329
SER A 331
 LLP  A 205 ( 4.4A)
None
None
None
 1.05A 5ny7A-3lwsA:
undetectable		 5ny7A-3lwsA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lws AROMATIC AMINO ACID
BETA-ELIMINATING
LYASE/THREONINE
ALDOLASE

(Exiguobacterium
sibiricum) 		PF01212
(Beta_elim_lyase) 		4 ARG A 145
GLY A 149
GLU A 329
SER A 331
 LLP  A 205 ( 4.4A)
None
None
None
 0.82A 5ny7A-3lwsA:
undetectable		 5ny7A-3lwsA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3njp EPIDERMAL GROWTH
FACTOR RECEPTOR

(Homo sapiens) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 ARG A 403
GLY A 379
GLU A 376
SER A 340
 None
 1.14A 5ny7A-3njpA:
undetectable		 5ny7A-3njpA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nsw EXCRETORY-SECRETORY
PROTEIN 2

(Ancylostoma
ceylanicum) 		no annotation 4 PRO A  49
THR A  20
GLU A  19
SER A  79
 None
 1.13A 5ny7A-3nswA:
undetectable		 5ny7A-3nswA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3org CMCLC

(Cyanidioschyzon
merolae) 		PF00654
(Voltage_CLC) 		4 ARG A 701
GLY A 707
PRO A 525
GLU A 702
 None
 0.93A 5ny7A-3orgA:
undetectable		 5ny7A-3orgA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3otl PUTATIVE
UNCHARACTERIZED
PROTEIN

(Rhizobium
leguminosarum) 		PF08327
(AHSA1) 		4 ARG A 135
THR A 104
GLU A 121
SER A 102
 MES  A 159 (-3.8A)
None
None
None
 1.01A 5ny7A-3otlA:
undetectable		 5ny7A-3otlA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pih UVRABC SYSTEM
PROTEIN A

(Thermotoga
maritima) 		PF00005
(ABC_tran) 		4 GLY A 647
THR A 630
GLU A 629
SER A 625
 None
None
None
PPV  A1001 ( 4.2A)
 1.13A 5ny7A-3pihA:
undetectable		 5ny7A-3pihA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poc ALPHA-GLUCOSIDASE

(Blautia obeum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ARG A 149
GLY A 152
THR A  17
GLU A  18
 None
 1.11A 5ny7A-3pocA:
undetectable		 5ny7A-3pocA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qwn HYPOTHETICAL
NIGD-LIKE PROTEIN

(Bacteroides
caccae) 		PF12667
(NigD_N)
PF17415
(NigD_C) 		4 GLY A 227
PRO A 226
THR A 203
GLU A 229
 None
 1.13A 5ny7A-3qwnA:
undetectable		 5ny7A-3qwnA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r64 NAD DEPENDENT
BENZALDEHYDE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF00171
(Aldedh) 		4 GLY A 334
PRO A 335
THR A 103
SER A 327
 GLY  A 334 ( 0.0A)
PRO  A 335 ( 1.1A)
THR  A 103 ( 0.8A)
SER  A 327 ( 0.0A)
 1.13A 5ny7A-3r64A:
undetectable		 5ny7A-3r64A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v75 OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Streptomyces
avermitilis) 		PF00215
(OMPdecase) 		4 ARG A 274
GLY A  18
PRO A  19
GLU A 271
 None
 1.11A 5ny7A-3v75A:
1.8		 5ny7A-3v75A:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vuu ERYTHROCYTE MEMBRANE
PROTEIN, PUTATIVE

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 ARG A 351
GLY A 354
THR A 355
GLU A 443
 None
 1.09A 5ny7A-3vuuA:
undetectable		 5ny7A-3vuuA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vz0 PUTATIVE
NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF00171
(Aldedh) 		4 ARG A 338
GLY A 304
PRO A 305
THR A 301
 None
 1.04A 5ny7A-3vz0A:
undetectable		 5ny7A-3vz0A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wvo CRISPR-ASSOCIATED
PROTEIN, CSE1 FAMILY

(Thermobifida
fusca) 		PF09481
(CRISPR_Cse1) 		4 ARG A  56
GLY A 201
THR A 300
GLU A 297
 None
 1.08A 5ny7A-3wvoA:
undetectable		 5ny7A-3wvoA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyt ESTERASE A

(Paenarthrobacter
nitroguajacolicus) 		PF00144
(Beta-lactamase) 		4 ARG A  36
GLY A  37
THR A 263
GLU A 337
 None
 0.94A 5ny7A-3zytA:
undetectable		 5ny7A-3zytA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b6c DNA GYRASE SUBUNIT B

(Mycolicibacterium
smegmatis) 		PF02518
(HATPase_c) 		4 ARG A  82
PRO A  85
THR A 169
GLU A  56
 B5U  A1256 (-3.4A)
B5U  A1256 (-4.2A)
B5U  A1256 (-3.6A)
B5U  A1256 (-3.6A)
 0.99A 5ny7A-4b6cA:
undetectable		 5ny7A-4b6cA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cd8 ENDO-BETA-1,4-MANNAN
ASE

(Alicyclobacillus
acidocaldarius) 		no annotation 4 ARG A 104
GLY A 149
GLU A 151
SER A 201
 MVL  A 400 (-2.9A)
None
MVL  A 400 (-2.6A)
MVL  A 400 ( 4.5A)
 1.00A 5ny7A-4cd8A:
4.0		 5ny7A-4cd8A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e8b RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E

(Escherichia
coli) 		PF04452
(Methyltrans_RNA) 		4 GLY A 194
PRO A 195
GLU A 203
SER A 200
 None
 0.96A 5ny7A-4e8bA:
2.2		 5ny7A-4e8bA:
25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ed9 CAIB/BAIF FAMILY
PROTEIN

(Brucella suis) 		PF02515
(CoA_transf_3) 		4 ARG A  46
THR A  75
GLU A  38
SER A  73
 None
 1.04A 5ny7A-4ed9A:
undetectable		 5ny7A-4ed9A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ia5 MYOSIN-CROSSREACTIVE
ANTIGEN

(Lactobacillus
acidophilus) 		PF06100
(MCRA) 		4 ARG A 125
GLY A 377
THR A 391
SER A 389
 None
None
None
MPD  A 605 ( 4.1A)
 1.12A 5ny7A-4ia5A:
undetectable		 5ny7A-4ia5A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j3c RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E

(Sinorhizobium
meliloti) 		PF04452
(Methyltrans_RNA) 		4 GLY A 195
PRO A 196
GLU A 204
SER A 201
 None
 0.98A 5ny7A-4j3cA:
undetectable		 5ny7A-4j3cA:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7h EVAA 2,3-DEHYDRATASE

(Amycolatopsis
orientalis) 		PF03559
(Hexose_dehydrat) 		4 ARG A 279
PRO A 114
THR A  85
GLU A  87
 None
 1.03A 5ny7A-4j7hA:
undetectable		 5ny7A-4j7hA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jf7 HEMAGGLUTININ-NEURAM
INIDASE

(Mammalian
rubulavirus 5) 		no annotation 4 ARG D 138
GLY D 137
THR D 483
GLU D 481
 None
None
None
NAG  D 606 ( 4.0A)
 0.89A 5ny7A-4jf7D:
undetectable		 5ny7A-4jf7D:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN

(Viscum album) 		PF00161
(RIP) 		4 ARG A   5
THR A  67
GLU A  57
SER A  65
 None
None
None
EDO  A 306 (-4.3A)
 1.10A 5ny7A-4jkxA:
undetectable		 5ny7A-4jkxA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnh GAG POLYPROTEIN

(Simian foamy
virus) 		PF03276
(Gag_spuma) 		4 GLY A 110
PRO A 111
GLU A  49
SER A 126
 None
 1.09A 5ny7A-4jnhA:
undetectable		 5ny7A-4jnhA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l5h VVTL1

(Vitis vinifera) 		PF00314
(Thaumatin) 		4 GLY A 158
THR A  86
GLU A  85
SER A  73
 None
 0.93A 5ny7A-4l5hA:
undetectable		 5ny7A-4l5hA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcm TRANSESTERASE

(Aspergillus
terreus) 		PF00144
(Beta-lactamase) 		4 ARG A  73
GLY A 271
THR A  78
SER A  76
 None
 0.98A 5ny7A-4lcmA:
undetectable		 5ny7A-4lcmA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mlz PERIPLASMIC BINDING
PROTEIN

(Jonesia
denitrificans) 		PF01497
(Peripla_BP_2) 		4 ARG A 336
GLY A 334
GLU A  89
SER A  85
 None
 1.00A 5ny7A-4mlzA:
undetectable		 5ny7A-4mlzA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nmi ECTD

(Virgibacillus
salexigens) 		PF05721
(PhyH) 		4 ARG A  18
GLY A  47
THR A 246
SER A 244
 None
 1.10A 5ny7A-4nmiA:
undetectable		 5ny7A-4nmiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nx1 C4-DICARBOXYLATE
TRANSPORT SYSTEM
SUBSTRATE-BINDING
PROTEIN

(Sulfitobacter
sp. NAS-14.1) 		PF03480
(DctP) 		4 ARG A 153
GLY A 149
GLU A 214
SER A 217
 X1X  A 401 (-3.1A)
None
X1X  A 401 (-2.7A)
X1X  A 401 (-3.7A)
 1.06A 5ny7A-4nx1A:
undetectable		 5ny7A-4nx1A:
25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oqr CYP105AS1

(Amycolatopsis
orientalis) 		PF00067
(p450) 		4 ARG A 364
GLY A 361
THR A 129
GLU A 130
 None
 0.94A 5ny7A-4oqrA:
undetectable		 5ny7A-4oqrA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9c NOVEL ANTIGEN
RECEPTOR

(Ginglymostoma
cirratum) 		PF07654
(C1-set) 		4 ARG A 375
GLY A 376
THR A 409
GLU A 405
 CL  A 903 (-4.1A)
PG4  A 902 ( 4.1A)
PG4  A 902 ( 4.7A)
PG4  A 902 (-4.5A)
 1.11A 5ny7A-4q9cA:
undetectable		 5ny7A-4q9cA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qaw XYN30D

(Paenibacillus
barcinonensis) 		PF03422
(CBM_6)
PF17189
(Glyco_hydro_30C) 		4 ARG A 511
GLY A 476
THR A 509
GLU A 443
 None
 1.09A 5ny7A-4qawA:
undetectable		 5ny7A-4qawA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qhx UNCHARACTERIZED
PROTEIN

(Bacteroides
caccae) 		PF11958
(DUF3472)
PF16871
(DUF5077) 		4 ARG A 157
GLY A 155
THR A 362
SER A 160
 PEG  A 520 ( 4.4A)
None
PEG  A 519 (-4.2A)
SO4  A 508 (-3.8A)
 1.06A 5ny7A-4qhxA:
undetectable		 5ny7A-4qhxA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r10 PROTEIN HUMPBACK-2

(Caenorhabditis
elegans) 		PF00514
(Arm) 		4 ARG A 557
GLY A 561
GLU A 558
SER A 504
 None
 1.08A 5ny7A-4r10A:
undetectable		 5ny7A-4r10A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xlw DELTA-LIKE PROTEIN

(Rattus
norvegicus) 		PF01414
(DSL)
PF07657
(MNNL) 		4 ARG B  55
GLY B  53
PRO B  52
THR B  86
 None
 1.01A 5ny7A-4xlwB:
undetectable		 5ny7A-4xlwB:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y23 GAMMA GLUTAMYL
TRANSPEPTIDASE,GAMMA
-GLUTAMYLTRANSPEPTID
ASE

(Bacillus
licheniformis) 		PF01019
(G_glu_transpept) 		4 ARG A 136
GLY A 425
THR A 197
SER A 195
 None
 0.70A 5ny7A-4y23A:
undetectable		 5ny7A-4y23A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awp ISOMALTODEXTRANASE

(Arthrobacter
globiformis) 		no annotation 4 GLY A 554
PRO A 555
THR A 551
GLU A 545
 None
 1.13A 5ny7A-5awpA:
1.6		 5ny7A-5awpA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bwi GLYCOSIDE HYDROLASE
FAMILY 79

(Burkholderia
pseudomallei) 		PF12891
(Glyco_hydro_44) 		4 GLY A  80
PRO A  81
THR A  89
SER A  41
 None
 1.10A 5ny7A-5bwiA:
2.9		 5ny7A-5bwiA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chc DMSO REDUCTASE
FAMILY TYPE II
ENZYME,
MOLYBDOPTERIN
SUBUNIT

(Azospira oryzae) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 ARG A 208
GLY A  38
GLU A 595
SER A 594
 MGD  A1003 ( 3.6A)
SF4  A1001 ( 3.8A)
None
None
 1.06A 5ny7A-5chcA:
undetectable		 5ny7A-5chcA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dt9 ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE

(Vibrio cholerae) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
PF11890
(DUF3410) 		4 ARG A  34
GLY A  33
THR A  53
SER A  51
 None
None
None
SO4  A 404 (-2.3A)
 1.09A 5ny7A-5dt9A:
undetectable		 5ny7A-5dt9A:
24.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gmt ALGINATE LYASE

(Aplysia kurodai) 		no annotation 4 ARG A 132
GLY A 170
GLU A 138
SER A 166
 None
 1.14A 5ny7A-5gmtA:
undetectable		 5ny7A-5gmtA:
23.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5jqn ALIPHATIC AMIDASE

(Nesterenkonia
sp. AN1) 		PF00795
(CN_hydrolase) 		6 ARG A  65
GLY A  85
PRO A  86
THR A  95
GLU A  97
SER A 108
 None
 0.14A 5ny7A-5jqnA:
48.4		 5ny7A-5jqnA:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k7m N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14

(Homo sapiens) 		PF05063
(MT-A70) 		4 ARG B 354
GLY B 356
PRO B 355
GLU B 335
 None
 0.82A 5ny7A-5k7mB:
undetectable		 5ny7A-5k7mB:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		4 GLY A 243
PRO A 244
THR A 387
SER A 391
 None
 0.94A 5ny7A-5kqiA:
undetectable		 5ny7A-5kqiA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6e N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14

(Homo sapiens) 		PF05063
(MT-A70) 		4 ARG B 354
GLY B 356
PRO B 355
GLU B 335
 None
 0.83A 5ny7A-5l6eB:
undetectable		 5ny7A-5l6eB:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6f FAD LINKED
OXIDASE-LIKE PROTEIN

(Thermothelomyces
thermophila) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 GLY A 335
PRO A 334
THR A  48
GLU A  45
 None
 1.09A 5ny7A-5l6fA:
undetectable		 5ny7A-5l6fA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m6g BETA-GLUCOSIDASE

(Saccharopolyspora
erythraea) 		no annotation 4 ARG A 482
GLY A 435
THR A 523
GLU A 519
 None
 1.11A 5ny7A-5m6gA:
1.8		 5ny7A-5m6gA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oar BETA-HEXOSAMINIDASE
BETA-HEXOSAMINIDASE

(Aspergillus
oryzae;
Aspergillus
oryzae) 		no annotation
no annotation 		4 ARG B 560
PRO A  23
GLU B 539
SER B 543
 None
 1.07A 5ny7A-5oarB:
2.2		 5ny7A-5oarB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oie -

(-) 		no annotation 4 ARG A 348
GLY A 346
PRO A 347
SER A 364
 None
 1.13A 5ny7A-5oieA:
undetectable		 5ny7A-5oieA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyp STRUCTURAL PROTEIN
VP3

(Sacbrood virus) 		no annotation 4 GLY C  87
PRO C  86
THR C 182
SER C 210
 None
 1.06A 5ny7A-5oypC:
undetectable		 5ny7A-5oypC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tey N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14

(Homo sapiens) 		PF05063
(MT-A70) 		4 ARG B 354
GLY B 356
PRO B 355
GLU B 335
 UNX  B 404 ( 4.0A)
None
None
None
 0.78A 5ny7A-5teyB:
undetectable		 5ny7A-5teyB:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM2
DNA REPLICATION
LICENSING FACTOR
MCM6

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB)
PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ARG 2 656
GLY 2 546
PRO 2 545
THR 6 796
 None
AGS  22001 ( 4.4A)
AGS  22001 ( 4.4A)
None
 1.07A 5ny7A-5udb2:
undetectable		 5ny7A-5udb2:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA
MDCC

(Pseudomonas
aeruginosa;
Pseudomonas
protegens) 		PF16957
(Mal_decarbox_Al)
PF06857
(ACP) 		4 ARG C  86
GLY C  83
THR A 423
GLU A 466
 None
 1.01A 5ny7A-5vj1C:
undetectable		 5ny7A-5vj1C:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wmm NRPS

(Micromonospora
sp. ML1) 		no annotation 4 ARG A 839
THR A 812
GLU A 822
SER A 814
 None
 1.10A 5ny7A-5wmmA:
undetectable		 5ny7A-5wmmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xh9 EXTRACELLULAR
INVERTASE

(Aspergillus
kawachii) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 GLY A 182
PRO A 183
GLU A 157
SER A 156
 None
 0.92A 5ny7A-5xh9A:
undetectable		 5ny7A-5xh9A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y50 PROTEIN
DETOXIFICATION 14

(Arabidopsis
thaliana) 		no annotation 4 GLY A 395
THR A  90
GLU A  89
SER A  86
 None
 1.07A 5ny7A-5y50A:
undetectable		 5ny7A-5y50A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MEMBRANE-BOUND
HYDROGENASE SUBUNIT
ALPHA

(Pyrococcus
furiosus) 		no annotation 4 ARG L 231
GLY L 103
GLU L 104
SER L 275
 None
 1.11A 5ny7A-6cfwL:
undetectable		 5ny7A-6cfwL:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eh1 STRUCTURAL PROTEIN
VP3

(Sacbrood virus) 		no annotation 4 GLY C  87
PRO C  86
THR C 182
SER C 210
 None
 1.00A 5ny7A-6eh1C:
undetectable		 5ny7A-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eq8 PERIPLASMIC
ALPHA-GALACTOSIDE-BI
NDING PROTEIN

(Agrobacterium
tumefaciens) 		no annotation 4 GLY D 423
PRO D 422
GLU D 614
SER D 427
 None
 0.98A 5ny7A-6eq8D:
undetectable		 5ny7A-6eq8D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f9c GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		no annotation 4 ARG A 161
GLY A 163
PRO A 162
GLU A 214
 None
 0.85A 5ny7A-6f9cA:
undetectable		 5ny7A-6f9cA:
undetectable