SIMILAR PATTERNS OF AMINO ACIDS FOR 5NWW_A_ACAA18

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awc PROTEIN (GA BINDING
PROTEIN ALPHA)

(Mus musculus) 		PF00178
(Ets) 		5 GLY A 361
GLN A 324
LEU A 326
GLU A 328
LEU A 329
 None
 0.79A 5nwwA-1awcA:
0.0		 5nwwA-1awcA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1awc PROTEIN (GA BINDING
PROTEIN ALPHA)

(Mus musculus) 		PF00178
(Ets) 		5 GLY A 361
GLN A 324
LEU A 327
GLU A 328
LEU A 329
 None
 0.91A 5nwwA-1awcA:
0.0		 5nwwA-1awcA:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cpt CYTOCHROME P450-TERP

(Pseudomonas sp.) 		PF00067
(p450) 		5 GLY A 277
ASN A 286
GLN A 289
LEU A 290
LEU A 395
 None
 1.23A 5nwwA-1cptA:
0.0		 5nwwA-1cptA:
6.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dux ETS-DOMAIN PROTEIN
ELK-1

(Homo sapiens) 		PF00178
(Ets) 		5 GLY C  47
GLN C   9
LEU C  11
LEU C  12
LEU C  14
 None
 0.79A 5nwwA-1duxC:
0.0		 5nwwA-1duxC:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i0a DELTA CRYSTALLIN I

(Meleagris
gallopavo) 		PF00206
(Lyase_1)
PF14698
(ASL_C2) 		5 LYS A 299
GLN A 138
LEU A 136
LEU A 137
LEU A 180
 None
 1.19A 5nwwA-1i0aA:
0.0		 5nwwA-1i0aA:
4.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i7q TRPG

(Serratia
marcescens) 		PF00117
(GATase) 		5 GLY B  36
GLN B  78
LEU B  53
LEU B  79
LEU B   5
 None
 1.27A 5nwwA-1i7qB:
0.0		 5nwwA-1i7qB:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		5 GLY S  43
SER S  39
GLN S  62
GLU S  45
LEU S  61
 None
 1.27A 5nwwA-1i84S:
0.3		 5nwwA-1i84S:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ic2 TROPOMYOSIN ALPHA
CHAIN, SKELETAL
MUSCLE

(Gallus gallus) 		PF12718
(Tropomyosin_1) 		5 GLN A  68
GLU A  69
LEU A  71
GLU A  72
LEU A  73
 None
 1.25A 5nwwA-1ic2A:
0.0		 5nwwA-1ic2A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mc3 GLUCOSE-1-PHOSPHATE
THYMIDYLYLTRANSFERAS
E

(Escherichia
coli) 		PF00483
(NTP_transferase) 		5 GLN A 280
LEU A 282
LEU A 283
GLU A 284
LEU A 285
 None
 0.75A 5nwwA-1mc3A:
0.0		 5nwwA-1mc3A:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mdm C-ETS-1 PROTEIN

(Mus musculus) 		PF00178
(Ets) 		5 GLY B 376
GLN B 339
LEU B 341
GLU B 343
LEU B 344
 None
 0.88A 5nwwA-1mdmB:
0.0		 5nwwA-1mdmB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mdm C-ETS-1 PROTEIN

(Mus musculus) 		PF00178
(Ets) 		5 GLY B 376
GLN B 339
LEU B 342
GLU B 343
LEU B 344
 None
 1.16A 5nwwA-1mdmB:
0.0		 5nwwA-1mdmB:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nxk MAP KINASE-ACTIVATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		5 GLY A  71
LYS A  77
LEU A 192
GLU A 145
LEU A 193
 STU  A 401 (-3.6A)
None
None
None
STU  A 401 (-4.7A)
 1.07A 5nwwA-1nxkA:
undetectable		 5nwwA-1nxkA:
6.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw4 GLYCEROL-3-PHOSPHATE
TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		5 SER A 313
LYS A 315
LEU A 370
LEU A 373
GLU A 374
 None
 1.20A 5nwwA-1pw4A:
undetectable		 5nwwA-1pw4A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tzs CATHEPSIN E

(Homo sapiens) 		PF00026
(Asp) 		5 GLY A  45
SER A  46
LEU A  17
LEU A  21
GLU A  24
 None
 1.04A 5nwwA-1tzsA:
undetectable		 5nwwA-1tzsA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u5u ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		no annotation 5 GLY A  39
LYS A  41
ASN A 343
LEU A 333
GLU A 335
 None
 1.15A 5nwwA-1u5uA:
undetectable		 5nwwA-1u5uA:
7.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9l GLUTAMATE
DEHYDROGENASE

(Pyrobaculum
islandicum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		5 GLY A  48
GLN A 117
GLU A 119
LEU A 115
LEU A 120
 None
 1.17A 5nwwA-1v9lA:
undetectable		 5nwwA-1v9lA:
6.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmi HYPOTHETICAL PROTEIN
PHS014

(Pyrococcus
horikoshii) 		no annotation 5 GLU B  43
LEU B  44
LEU B  45
GLU B  46
LEU B  47
 None
 0.69A 5nwwA-1wmiB:
undetectable		 5nwwA-1wmiB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yo5 SAM POINTED DOMAIN
CONTAINING ETS
TRANSCRIPTION FACTOR

(Homo sapiens) 		PF00178
(Ets) 		5 GLY C 292
GLN C 253
LEU C 255
GLU C 257
LEU C 258
 None
 0.74A 5nwwA-1yo5C:
undetectable		 5nwwA-1yo5C:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zao RIO2 SERINE KINASE

(Archaeoglobus
fulgidus) 		PF01163
(RIO1)
PF09202
(Rio2_N) 		5 GLY A  11
SER A  14
LYS A  12
ASN A  49
LEU A  57
 None
 1.08A 5nwwA-1zaoA:
undetectable		 5nwwA-1zaoA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy8 DIHYDROLIPOYL
DEHYDROGENASE,
MITOCHONDRIAL

(Homo sapiens) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 GLY A 119
LYS A 285
LEU A 289
GLU A 291
LEU A 292
 FAD  A4750 (-4.3A)
None
None
None
None
 1.24A 5nwwA-1zy8A:
undetectable		 5nwwA-1zy8A:
5.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afh NITROGENASE
MOLYBDENUM-IRON
PROTEIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		5 GLY B 489
LEU B 383
LEU B 384
GLU B 385
LEU B 386
 None
 0.98A 5nwwA-2afhB:
undetectable		 5nwwA-2afhB:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3o TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 6

(Homo sapiens) 		PF00017
(SH2)
PF00102
(Y_phosphatase) 		5 GLY A 497
SER A 496
ASN A 278
GLU A  74
LEU A 259
 None
 1.14A 5nwwA-2b3oA:
undetectable		 5nwwA-2b3oA:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2de2 DIBENZOTHIOPHENE
DESULFURIZATION
ENZYME B

(Rhodococcus sp.
IGTS8) 		no annotation 5 GLY A 153
SER A 154
ASN A 340
LEU A 342
LEU A  79
 None
 1.17A 5nwwA-2de2A:
undetectable		 5nwwA-2de2A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dxq ACETYLTRANSFERASE

(Agrobacterium
fabrum) 		PF00583
(Acetyltransf_1) 		5 GLY A  60
LEU A  19
LEU A  20
GLU A  21
LEU A  22
 None
 0.95A 5nwwA-2dxqA:
undetectable		 5nwwA-2dxqA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eq9 PYRUVATE
DEHYDROGENASE
COMPLEX,
DIHYDROLIPOAMIDE
DEHYDROGENASE E3
COMPONENT

(Thermus
thermophilus) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		5 GLY A 139
LYS A 125
LEU A 114
GLU A 113
LEU A 115
 None
 1.14A 5nwwA-2eq9A:
undetectable		 5nwwA-2eq9A:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f31 DIAPHANOUS PROTEIN
HOMOLOG 1

(Mus musculus) 		PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		5 GLY A 292
GLN A 336
LEU A 338
GLU A 340
LEU A 341
 None
 1.07A 5nwwA-2f31A:
undetectable		 5nwwA-2f31A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g5d GNA33

(Neisseria
gonorrhoeae) 		PF03562
(MltA)
PF06725
(3D) 		5 GLY A 291
ASN A 317
GLN A 319
LEU A 321
GLU A 323
 None
 0.97A 5nwwA-2g5dA:
undetectable		 5nwwA-2g5dA:
6.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l3j DOUBLE-STRANDED
RNA-SPECIFIC EDITASE
1

(Rattus
norvegicus) 		PF00035
(dsrm) 		5 GLN A  12
LEU A  10
LEU A  13
GLU A  63
LEU A  59
 None
G  B 277 ( 3.5A)
None
None
None
 1.25A 5nwwA-2l3jA:
undetectable		 5nwwA-2l3jA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1t PUTATIVE NUCLEOTIDE
SUGAR EPIMERASE/
DEHYDRATASE

(Bordetella
bronchiseptica) 		PF01370
(Epimerase) 		5 GLY A 249
LEU A  32
LEU A  33
GLU A  34
LEU A  35
 None
 0.95A 5nwwA-2q1tA:
undetectable		 5nwwA-2q1tA:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qcv PUTATIVE
5-DEHYDRO-2-DEOXYGLU
CONOKINASE

(Bacillus
halodurans) 		PF00294
(PfkB) 		5 GLY A  52
SER A  53
LYS A  55
GLU A 174
LEU A 142
 None
None
None
PGE  A 332 (-3.0A)
None
 0.95A 5nwwA-2qcvA:
undetectable		 5nwwA-2qcvA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww9 SEC SIXTY-ONE
PROTEIN HOMOLOG

(Saccharomyces
cerevisiae) 		PF00344
(SecY)
PF10559
(Plug_translocon) 		5 GLY A  52
LEU A  79
LEU A  80
GLU A  81
LEU A 157
 None
 1.26A 5nwwA-2ww9A:
undetectable		 5nwwA-2ww9A:
5.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xio PUTATIVE
DEOXYRIBONUCLEASE
TATDN1

(Homo sapiens) 		PF01026
(TatD_DNase) 		5 GLY A  82
ASN A  88
LEU A  93
GLU A  95
LEU A  96
 None
 1.23A 5nwwA-2xioA:
undetectable		 5nwwA-2xioA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ypr PROTEIN FEV

(Homo sapiens) 		PF00178
(Ets) 		5 GLY A  88
GLN A  51
LEU A  53
LEU A  54
LEU A  56
 None
 1.03A 5nwwA-2yprA:
undetectable		 5nwwA-2yprA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ypr PROTEIN FEV

(Homo sapiens) 		PF00178
(Ets) 		5 GLY A  88
LEU A  53
LEU A  54
GLU A  55
LEU A  56
 None
 0.94A 5nwwA-2yprA:
undetectable		 5nwwA-2yprA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z1a 5'-NUCLEOTIDASE

(Thermus
thermophilus) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		5 GLY A 362
LYS A 366
ASN A 479
LEU A 376
LEU A 435
 None
None
THM  A6510 ( 4.7A)
None
None
 1.12A 5nwwA-2z1aA:
undetectable		 5nwwA-2z1aA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z63 TOLL-LIKE RECEPTOR
4, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF11921
(DUF3439)
PF13516
(LRR_6)
PF13855
(LRR_8) 		5 GLY A  70
SER A  73
LYS A  47
LEU A  61
LEU A  85
 None
 1.22A 5nwwA-2z63A:
undetectable		 5nwwA-2z63A:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zcw TRANSCRIPTIONAL
REGULATOR, FNR/CRP
FAMILY

(Thermus
thermophilus) 		PF00027
(cNMP_binding)
PF13545
(HTH_Crp_2) 		5 GLY A 156
LEU A 126
LEU A 127
GLU A 128
LEU A 129
 None
 1.05A 5nwwA-2zcwA:
undetectable		 5nwwA-2zcwA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bgf F26G19 FAB

(Mus musculus) 		no annotation 5 GLY H 104
GLN L  37
LEU L  36
GLU L  38
LEU H  45
 None
 1.22A 5nwwA-3bgfH:
undetectable		 5nwwA-3bgfH:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bt6 INFLUENZA B
HEMAGGLUTININ (HA)

(Influenza B
virus) 		PF00509
(Hemagglutinin) 		5 GLY B   8
LEU B 115
LEU B 118
GLU B 119
LEU B 116
 None
 1.24A 5nwwA-3bt6B:
undetectable		 5nwwA-3bt6B:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwt PROTEIN PUF4

(Saccharomyces
cerevisiae) 		PF00806
(PUF) 		5 GLY A 722
ASN A 759
GLN A 763
LEU A 752
LEU A 745
 None
 1.22A 5nwwA-3bwtA:
undetectable		 5nwwA-3bwtA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cue TRANSPORT PROTEIN
PARTICLE 22 KDA
SUBUNIT
TRANSPORT PROTEIN
PARTICLE 31 KDA
SUBUNIT

(Saccharomyces
cerevisiae) 		PF04051
(TRAPP) 		5 GLY D  35
LEU B  98
LEU B  99
GLU B 100
LEU B 101
 None
 1.05A 5nwwA-3cueD:
undetectable		 5nwwA-3cueD:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3q TRNA
DELTA(2)-ISOPENTENYL
PYROPHOSPHATE
TRANSFERASE

(Staphylococcus
epidermidis) 		PF01715
(IPPT) 		5 ASN A 228
GLN A 231
GLU A 229
LEU A 226
LEU A 252
 None
 1.24A 5nwwA-3d3qA:
undetectable		 5nwwA-3d3qA:
8.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e3r CALCYPHOSIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		5 GLY A  73
SER A  74
GLU A  81
LEU A  83
LEU A  77
 None
CA  A 192 (-2.5A)
CA  A 192 (-2.3A)
None
None
 1.06A 5nwwA-3e3rA:
undetectable		 5nwwA-3e3rA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdf PROBABLE
NADP-DEPENDENT
MANNITOL
DEHYDROGENASE

(Cladosporium
herbarum) 		PF13561
(adh_short_C2) 		5 GLY A 153
SER A 154
GLN A  15
LEU A  16
LEU A  18
 None
 1.25A 5nwwA-3gdfA:
undetectable		 5nwwA-3gdfA:
9.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j3r ADAPTER PROTEIN MECA
1

(Bacillus
subtilis) 		PF05389
(MecA) 		5 GLY 1 149
SER 1 150
ASN 1 177
LEU 1 179
LEU 1 182
 None
 1.17A 5nwwA-3j3r1:
undetectable		 5nwwA-3j3r1:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mi9 CELL DIVISION
PROTEIN KINASE 9

(Homo sapiens) 		PF00069
(Pkinase) 		5 GLY A 214
LEU A 200
LEU A 201
GLU A 198
LEU A 199
 None
 1.06A 5nwwA-3mi9A:
undetectable		 5nwwA-3mi9A:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prx COBRA VENOM FACTOR

(Naja kaouthia) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2)
PF10569
(Thiol-ester_cl) 		5 GLY B 612
SER B 535
ASN B 617
LEU B 628
GLU B 622
 None
 1.25A 5nwwA-3prxB:
undetectable		 5nwwA-3prxB:
2.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr3 MICROCIN IMMUNITY
PROTEIN MCCF

(Bacillus
anthracis) 		PF02016
(Peptidase_S66) 		5 SER A  82
ASN A 210
LEU A 118
LEU A 119
LEU A 117
 None
 1.26A 5nwwA-3sr3A:
undetectable		 5nwwA-3sr3A:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3txx PUTRESCINE
CARBAMOYLTRANSFERASE

(Enterococcus
faecalis) 		PF00185
(OTCace)
PF02729
(OTCace_N) 		5 GLY A 285
SER A 288
LYS A 286
ASN A 253
GLN A 251
 None
 1.24A 5nwwA-3txxA:
undetectable		 5nwwA-3txxA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w0f ENDONUCLEASE 8-LIKE
3

(Mus musculus) 		PF06831
(H2TH) 		5 GLY A 204
SER A 203
ASN A 197
LEU A 182
LEU A 178
 None
 1.23A 5nwwA-3w0fA:
undetectable		 5nwwA-3w0fA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w5f BETA-GALACTOSIDASE

(Solanum
lycopersicum) 		PF01301
(Glyco_hydro_35) 		5 ASN A 376
GLN A 358
LEU A 374
LEU A 354
GLU A 359
 None
 1.21A 5nwwA-3w5fA:
undetectable		 5nwwA-3w5fA:
4.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wu1 PROTEIN C-ETS-1

(Homo sapiens) 		PF00178
(Ets) 		5 GLY B 376
GLN B 339
LEU B 341
GLU B 343
LEU B 344
 None
 0.95A 5nwwA-3wu1B:
undetectable		 5nwwA-3wu1B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wu1 PROTEIN C-ETS-1

(Homo sapiens) 		PF00178
(Ets) 		5 GLY B 376
GLN B 339
LEU B 342
GLU B 343
LEU B 344
 None
 1.11A 5nwwA-3wu1B:
undetectable		 5nwwA-3wu1B:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxb UNCHARACTERIZED
PROTEIN

(Gallus gallus) 		PF00106
(adh_short) 		5 GLY A 233
GLN A  24
LEU A  26
LEU A  27
LEU A  29
 None
 1.15A 5nwwA-3wxbA:
undetectable		 5nwwA-3wxbA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zgq INTERFERON-INDUCED
PROTEIN WITH
TETRATRICOPEPTIDE
REPEATS 5

(Homo sapiens) 		PF07719
(TPR_2)
PF13181
(TPR_8)
PF13374
(TPR_10)
PF13424
(TPR_12) 		5 GLY A 118
LEU A  13
LEU A  14
GLU A  15
LEU A  16
 None
 1.20A 5nwwA-3zgqA:
undetectable		 5nwwA-3zgqA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh2 L-LACTATE
DEHYDROGENASE

(Plasmodium
falciparum) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		6 GLY A  87
LYS A  88
ASN A  94
LEU A  98
LEU A  99
LEU A 101
 None
 1.42A 5nwwA-3zh2A:
undetectable		 5nwwA-3zh2A:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zil AAR187CP

(Eremothecium
gossypii) 		PF16997
(Wap1) 		5 GLY A 399
LYS A 404
ASN A 407
LEU A 463
LEU A 467
 None
 1.28A 5nwwA-3zilA:
undetectable		 5nwwA-3zilA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4emo SHARPIN

(Homo sapiens) 		PF16764
(Sharpin_PH) 		5 GLY A  34
GLN A  90
LEU A  99
LEU A  89
GLU A  88
 None
 1.03A 5nwwA-4emoA:
undetectable		 5nwwA-4emoA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3h ARGINASE (ROCF)

(Helicobacter
pylori) 		PF00491
(Arginase) 		5 GLY A  20
LYS A  19
GLN A 297
LEU A 299
LEU A 302
 None
 1.07A 5nwwA-4g3hA:
undetectable		 5nwwA-4g3hA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ht1 CHIMERIC ANTIBODY
FAB
TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER
12

(Homo sapiens;
Oryctolagus
cuniculus) 		PF00229
(TNF)
PF07654
(C1-set)
PF07686
(V-set) 		5 SER L  52
LYS L  63
GLN T  28
GLU T  76
LEU T 134
 None
 1.24A 5nwwA-4ht1L:
undetectable		 5nwwA-4ht1L:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iri TRANSCRIPTIONAL
REGULATOR ERG

(Homo sapiens) 		PF00178
(Ets) 		6 GLY A 335
GLN A 298
LEU A 300
LEU A 301
GLU A 302
LEU A 303
 None
 0.78A 5nwwA-4iriA:
undetectable		 5nwwA-4iriA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kf7 NUP188

(Thermothelomyces
thermophila) 		PF10487
(Nup188) 		5 GLY A 150
LYS A1056
ASN A 144
LEU A 137
LEU A 162
 None
 1.22A 5nwwA-4kf7A:
undetectable		 5nwwA-4kf7A:
2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfv BETA-CATENIN-LIKE
PROTEIN 1

(Homo sapiens) 		PF08216
(CTNNBL) 		5 ASN A 141
GLN A 144
LEU A 146
LEU A 147
LEU A 149
 None
 1.03A 5nwwA-4mfvA:
undetectable		 5nwwA-4mfvA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nss MYCOBACTERIAL
PROTEIN

(Mycolicibacterium
smegmatis) 		no annotation 5 GLY A 104
SER A 106
LEU A  92
LEU A  97
LEU A  93
 None
 1.26A 5nwwA-4nssA:
undetectable		 5nwwA-4nssA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pju COHESIN SUBUNIT SA-2

(Homo sapiens) 		PF08514
(STAG) 		5 GLN A 269
LEU A 267
LEU A 266
GLU A 265
LEU A 264
 None
 1.24A 5nwwA-4pjuA:
undetectable		 5nwwA-4pjuA:
3.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pk1 CHIMERA PROTEIN OF
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTORS BAMA AND
BAMB

(Escherichia
coli) 		PF07244
(POTRA)
PF13360
(PQQ_2) 		5 GLY A1057
ASN A1062
LEU A1111
GLU A1127
LEU A1110
 None
 1.21A 5nwwA-4pk1A:
undetectable		 5nwwA-4pk1A:
4.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q69 PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		5 GLY A 239
GLU A 352
LEU A 349
LEU A 350
LEU A 372
 None
 0.98A 5nwwA-4q69A:
undetectable		 5nwwA-4q69A:
5.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qyj ALDEHYDE
DEHYDROGENASE

(Pseudomonas
putida) 		PF00171
(Aldedh) 		5 GLY A 331
SER A 332
ASN A 104
LEU A 102
LEU A  43
 None
 1.20A 5nwwA-4qyjA:
undetectable		 5nwwA-4qyjA:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tzh LIC12234

(Leptospira
interrogans) 		PF13855
(LRR_8) 		5 GLY A 131
LYS A 151
LEU A 176
LEU A 203
LEU A 179
 None
 1.22A 5nwwA-4tzhA:
undetectable		 5nwwA-4tzhA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1r ATP-DEPENDENT
6-PHOSPHOFRUCTOKINAS
E, PLATELET TYPE

(Homo sapiens) 		PF00365
(PFK) 		5 GLY A 449
LEU A 515
LEU A 516
GLU A 517
LEU A 518
 None
 0.92A 5nwwA-4u1rA:
undetectable		 5nwwA-4u1rA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uxv SEPTATION RING
FORMATION REGULATOR
EZRA

(Bacillus
subtilis) 		PF06160
(EzrA) 		5 GLY A 344
ASN A 469
LEU A 408
GLU A 333
LEU A 405
 None
 1.14A 5nwwA-4uxvA:
undetectable		 5nwwA-4uxvA:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xwj PHOSPHOCARRIER
PROTEIN HPR

(Escherichia
coli) 		PF00381
(PTS-HPr) 		5 GLY B  67
SER B  31
GLN B   4
LEU B  77
GLU B  75
 None
 1.19A 5nwwA-4xwjB:
undetectable		 5nwwA-4xwjB:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z0c TOLL-LIKE RECEPTOR
13

(Mus musculus) 		PF00560
(LRR_1)
PF13516
(LRR_6)
PF13855
(LRR_8) 		5 GLY A 363
LYS A 365
GLN A 355
LEU A 403
LEU A 384
 None
 1.25A 5nwwA-4z0cA:
undetectable		 5nwwA-4z0cA:
4.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zuz SIDC

(Legionella
pneumophila) 		no annotation 5 LYS A 556
GLN A 572
LEU A 589
LEU A 575
LEU A 540
 None
 1.06A 5nwwA-4zuzA:
undetectable		 5nwwA-4zuzA:
3.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zy7 UNCHARACTERIZED
PROTEIN MSMEG_5817

(Mycolicibacterium
smegmatis) 		no annotation 5 GLY A 104
SER A 106
LEU A  92
LEU A  97
LEU A  93
 None
None
EDO  A 202 (-4.8A)
None
None
 1.23A 5nwwA-4zy7A:
undetectable		 5nwwA-4zy7A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9e SEPL

(Escherichia
coli) 		PF07201
(HrpJ) 		5 SER A 231
ASN A  86
GLN A  89
GLU A  90
LEU A  94
 None
 1.22A 5nwwA-5c9eA:
undetectable		 5nwwA-5c9eA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c9e SEPL

(Escherichia
coli) 		PF07201
(HrpJ) 		5 SER A 231
ASN A  86
GLN A  89
LEU A  91
LEU A  94
 None
 1.20A 5nwwA-5c9eA:
undetectable		 5nwwA-5c9eA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ci6 MITOGEN-ACTIVATED
PROTEIN KINASE 6

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		5 LYS A 191
LEU A 235
LEU A 236
GLU A 233
LEU A 234
 None
 1.11A 5nwwA-5ci6A:
undetectable		 5nwwA-5ci6A:
6.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzt CYLM

(Enterococcus
faecalis) 		PF05147
(LANC_like)
PF13575
(DUF4135) 		5 GLY A 257
GLN A 146
GLU A 147
LEU A 148
LEU A 151
 None
 0.94A 5nwwA-5dztA:
undetectable		 5nwwA-5dztA:
3.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e8g FRIEND LEUKEMIA
INTEGRATION 1
TRANSCRIPTION FACTOR

(Homo sapiens) 		PF00178
(Ets) 		6 GLY A 322
GLN A 285
LEU A 287
LEU A 288
GLU A 289
LEU A 290
 None
 0.90A 5nwwA-5e8gA:
undetectable		 5nwwA-5e8gA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e8g FRIEND LEUKEMIA
INTEGRATION 1
TRANSCRIPTION FACTOR

(Homo sapiens) 		PF00178
(Ets) 		6 GLY A 322
LYS A 327
LEU A 287
LEU A 288
GLU A 289
LEU A 290
 None
 1.39A 5nwwA-5e8gA:
undetectable		 5nwwA-5e8gA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f38 ACETYL-COA
ACETYLTRANSFERASE

(Escherichia
coli) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		5 GLY B 348
ASN B 246
GLN B 176
LEU B 179
LEU B 325
 None
 1.11A 5nwwA-5f38B:
undetectable		 5nwwA-5f38B:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5go2 PROTEIN AROA(G)

(Bacillus
subtilis) 		PF01817
(CM_2) 		5 GLN A  11
LEU A   9
LEU A   8
GLU A   7
LEU A   6
 None
 0.97A 5nwwA-5go2A:
undetectable		 5nwwA-5go2A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hb0 NUCLEOPORIN NUP170

(Chaetomium
thermophilum) 		no annotation 5 GLY B 938
LYS B 939
GLN B1033
LEU B1035
GLU B1037
 None
 1.05A 5nwwA-5hb0B:
undetectable		 5nwwA-5hb0B:
6.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hfi UNCHARACTERIZED
PROTEIN, CYTOSOLIC
DISULFIDE REDUCTASE
DSBM

(Pseudomonas
aeruginosa) 		PF01323
(DSBA) 		5 GLY A 124
LEU A 133
LEU A 134
GLU A 135
LEU A 136
 GLY  A 124 ( 0.0A)
LEU  A 133 ( 0.6A)
LEU  A 134 ( 0.6A)
GLU  A 135 ( 0.6A)
LEU  A 136 ( 0.6A)
 0.72A 5nwwA-5hfiA:
undetectable		 5nwwA-5hfiA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hxg UNCHARACTERIZED
PROTEIN STM1697

(Salmonella
enterica) 		PF00563
(EAL) 		5 GLY A  80
ASN A  76
GLN A 104
LEU A 103
LEU A 124
 None
 1.00A 5nwwA-5hxgA:
undetectable		 5nwwA-5hxgA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idn CYCLIN-DEPENDENT
KINASE 8

(Homo sapiens) 		PF00069
(Pkinase) 		5 LYS A 153
LEU A 205
LEU A 206
GLU A 203
LEU A 204
 FMT  A 403 ( 4.1A)
None
None
None
None
 1.16A 5nwwA-5idnA:
undetectable		 5nwwA-5idnA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvt FRIEND LEUKEMIA
INTEGRATION 1
TRANSCRIPTION FACTOR

(Homo sapiens) 		PF00178
(Ets) 		6 GLY A 322
GLN A 285
LEU A 287
LEU A 288
GLU A 289
LEU A 290
 None
 0.82A 5nwwA-5jvtA:
undetectable		 5nwwA-5jvtA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jvt FRIEND LEUKEMIA
INTEGRATION 1
TRANSCRIPTION FACTOR

(Homo sapiens) 		PF00178
(Ets) 		6 GLY A 322
LYS A 327
LEU A 287
LEU A 288
GLU A 289
LEU A 290
 None
 1.39A 5nwwA-5jvtA:
undetectable		 5nwwA-5jvtA:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbr SERINE/THREONINE-PRO
TEIN KINASE PAK 1

(Homo sapiens) 		PF00069
(Pkinase) 		5 ASN A 326
GLN A 375
LEU A 377
LEU A 374
GLU A 378
 None
 1.03A 5nwwA-5kbrA:
undetectable		 5nwwA-5kbrA:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kp0 FLAGELLAR PROTEIN
FLIT,FLAGELLUM-SPECI
FIC ATP SYNTHASE

(Salmonella
enterica) 		PF05400
(FliT) 		5 GLY A  28
GLN A  84
LEU A  86
GLU A  88
LEU A  89
 None
 0.93A 5nwwA-5kp0A:
undetectable		 5nwwA-5kp0A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpy PROTEIN
BRASSINOSTEROID
INSENSITIVE 1

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		5 SER A 990
LEU A1076
LEU A1077
GLU A1078
LEU A1079
 None
 0.92A 5nwwA-5lpyA:
undetectable		 5nwwA-5lpyA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lpz PROTEIN
BRASSINOSTEROID
INSENSITIVE 1

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		5 SER A 990
LEU A1076
LEU A1077
GLU A1078
LEU A1079
 None
 0.89A 5nwwA-5lpzA:
undetectable		 5nwwA-5lpzA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npu ANC27

(synthetic
construct) 		no annotation 5 GLY A 390
SER A 392
ASN A 467
LEU A 531
LEU A 437
 TPP  A 602 ( 3.7A)
TPP  A 602 ( 4.5A)
None
None
None
 1.24A 5nwwA-5npuA:
undetectable		 5nwwA-5npuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ui5 RNA POLYMERASE SIGMA
FACTOR RPON

(Aquifex
aeolicus) 		PF04552
(Sigma54_DBD)
PF04963
(Sigma54_CBD) 		5 GLY I 287
GLN I 340
GLU I 342
LEU I 338
LEU I 343
 None
 1.28A 5nwwA-5ui5I:
undetectable		 5nwwA-5ui5I:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vhj 26S PROTEASOME
REGULATORY SUBUNIT 4

(Homo sapiens) 		PF00004
(AAA) 		5 GLN B 315
LEU B 313
LEU B 312
GLU B 311
LEU B 310
 None
 1.25A 5nwwA-5vhjB:
undetectable		 5nwwA-5vhjB:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xjy ATP-BINDING CASSETTE
SUB-FAMILY A MEMBER
1

(Homo sapiens) 		PF00005
(ABC_tran)
PF12698
(ABC2_membrane_3) 		5 LYS A1410
LEU A1405
LEU A1404
GLU A1403
LEU A1402
 None
 1.25A 5nwwA-5xjyA:
undetectable		 5nwwA-5xjyA:
1.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d7t TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 6

(Homo sapiens) 		no annotation 5 GLY A 240
LEU A 292
LEU A 293
GLU A 294
LEU A 295
 None
 0.97A 5nwwA-6d7tA:
undetectable		 5nwwA-6d7tA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 HUNTINGTIN

(Homo sapiens) 		no annotation 5 GLN A2669
LEU A2671
LEU A2672
GLU A2673
LEU A2674
 None
 0.91A 5nwwA-6ez8A:
undetectable		 5nwwA-6ez8A:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f5d ATP SYNTHASE ALPHA
CHAIN, MITOCHONDRIAL

(Trypanosoma
brucei) 		no annotation 5 GLY A 162
SER A 444
ASN A 439
LEU A 437
LEU A 453
 None
 1.22A 5nwwA-6f5dA:
undetectable		 5nwwA-6f5dA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eu8 TREHALOSE/MALTOSE
BINDING PROTEIN

(Thermococcus
litoralis) 		PF01547
(SBP_bac_1) 		3 LYS A 347
TRP A 261
SER A 346
 CL  A 414 (-3.0A)
None
None
 1.18A 5nwwA-1eu8A:
0.0		 5nwwA-1eu8A:
8.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fc9 PHOTOSYSTEM II D1
PROTEASE

(Tetradesmus
obliquus) 		PF03572
(Peptidase_S41)
PF13180
(PDZ_2) 		3 LYS A 108
TRP A  89
SER A 105
 None
 1.28A 5nwwA-1fc9A:
0.0		 5nwwA-1fc9A:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khw RNA-DIRECTED RNA
POLYMERASE

(Rabbit
hemorrhagic
disease virus) 		PF00680
(RdRP_1) 		3 LYS A 253
TRP A 254
SER A 256
 None
 1.39A 5nwwA-1khwA:
undetectable		 5nwwA-1khwA:
5.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksi COPPER AMINE OXIDASE

(Pisum sativum) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		3 LYS A 396
TRP A 243
SER A 398
 None
 1.12A 5nwwA-1ksiA:
0.0		 5nwwA-1ksiA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0q SURFACE LAYER
PROTEIN

(Methanosarcina
mazei) 		PF00801
(PKD)
PF10282
(Lactonase) 		3 LYS A 348
TRP A 336
SER A 346
 None
 1.28A 5nwwA-1l0qA:
0.0		 5nwwA-1l0qA:
6.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lnl HEMOCYANIN

(Rapana venosa) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		3 LYS A 248
TRP A  69
SER A 251
 None
 1.20A 5nwwA-1lnlA:
0.0		 5nwwA-1lnlA:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mhm S-ADENOSYLMETHIONINE
DECARBOXYLASE

(Solanum
tuberosum) 		PF01536
(SAM_decarbox) 		3 LYS A 164
TRP A 165
SER A 119
 None
 1.38A 5nwwA-1mhmA:
0.0		 5nwwA-1mhmA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mpz OBTUSTATIN

(Macrovipera
lebetina) 		no annotation 3 LYS A  21
TRP A  20
SER A  26
 None
 1.04A 5nwwA-1mpzA:
undetectable		 5nwwA-1mpzA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nex CDC4 PROTEIN

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12937
(F-box-like) 		3 LYS B 724
TRP B 365
SER B 744
 None
 1.39A 5nwwA-1nexB:
0.0		 5nwwA-1nexB:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ssf TRANSFORMATION
RELATED PROTEIN 53
BINDING PROTEIN 1

(Mus musculus) 		PF09038
(53-BP1_Tudor) 		3 LYS A  17
TRP A  18
SER A  20
 None
 1.37A 5nwwA-1ssfA:
undetectable		 5nwwA-1ssfA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vl5 UNKNOWN CONSERVED
PROTEIN BH2331

(Bacillus
halodurans) 		PF08241
(Methyltransf_11) 		3 LYS A 174
TRP A 173
SER A 176
 None
 1.33A 5nwwA-1vl5A:
undetectable		 5nwwA-1vl5A:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcg THIOGLUCOSIDASE

(Brevicoryne
brassicae) 		PF00232
(Glyco_hydro_1) 		3 LYS A 285
TRP A 283
SER A 276
 None
 1.09A 5nwwA-1wcgA:
undetectable		 5nwwA-1wcgA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wt9 ANTICOAGULANT
PROTEIN-B

(Deinagkistrodon
acutus) 		PF00059
(Lectin_C) 		3 LYS B  70
TRP B  72
SER B  69
 None
 1.15A 5nwwA-1wt9B:
undetectable		 5nwwA-1wt9B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zzh CYTOCHROME C
PEROXIDASE

(Rhodobacter
capsulatus) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 LYS A 267
TRP A 269
SER A 265
 None
 0.85A 5nwwA-1zzhA:
undetectable		 5nwwA-1zzhA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aam HYPOTHETICAL PROTEIN
TM1410

(Thermotoga
maritima) 		PF03537
(Glyco_hydro_114) 		3 LYS A 103
TRP A 102
SER A 105
 None
 1.03A 5nwwA-2aamA:
undetectable		 5nwwA-2aamA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cof PROTEIN KIAA1914

(Homo sapiens) 		PF00169
(PH) 		3 LYS A  23
TRP A  22
SER A  24
 None
 1.34A 5nwwA-2cofA:
undetectable		 5nwwA-2cofA:
15.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cu9 HISTONE CHAPERONE
CIA1

(Schizosaccharomyces
pombe) 		PF04729
(ASF1_hist_chap) 		3 LYS A 140
TRP A 142
SER A 139
 None
 1.20A 5nwwA-2cu9A:
undetectable		 5nwwA-2cu9A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dnp RNA-BINDING PROTEIN
14

(Homo sapiens) 		PF00076
(RRM_1) 		3 LYS A  80
TRP A  79
SER A 147
 None
 1.30A 5nwwA-2dnpA:
undetectable		 5nwwA-2dnpA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erv HYPOTHETICAL PROTEIN
PAER03002360

(Pseudomonas
aeruginosa) 		PF09411
(PagL) 		3 LYS A  57
TRP A  48
SER A  89
 None
 1.04A 5nwwA-2ervA:
undetectable		 5nwwA-2ervA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f9q CYTOCHROME P450 2D6

(Homo sapiens) 		PF00067
(p450) 		3 LYS A 404
TRP A 409
SER A 400
 None
 1.25A 5nwwA-2f9qA:
undetectable		 5nwwA-2f9qA:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuk SEED LIPOXYGENASE

(Glycine max) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 LYS A 648
TRP A 650
SER A 706
 None
 1.32A 5nwwA-2iukA:
undetectable		 5nwwA-2iukA:
3.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j2m CATALASE

(Exiguobacterium
oxidotolerans) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 LYS A 192
TRP A 258
SER A 189
 None
 1.30A 5nwwA-2j2mA:
undetectable		 5nwwA-2j2mA:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qpz NAPHTHALENE
1,2-DIOXYGENASE
SYSTEM FERREDOXIN
SUBUNIT

(Pseudomonas
putida) 		PF00355
(Rieske) 		3 LYS A   1
TRP A   4
SER A 103
 None
 0.92A 5nwwA-2qpzA:
undetectable		 5nwwA-2qpzA:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2tdd THYMIDYLATE SYNTHASE

(Lactobacillus
casei) 		PF00303
(Thymidylat_synt) 		3 LYS A  92
TRP A  90
SER A  93
 None
 1.37A 5nwwA-2tddA:
undetectable		 5nwwA-2tddA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v72 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF00754
(F5_F8_type_C) 		3 LYS A  39
TRP A  40
SER A  17
 None
GAL  A1140 (-3.5A)
None
 1.40A 5nwwA-2v72A:
undetectable		 5nwwA-2v72A:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmc EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E

(Pisum sativum) 		PF01652
(IF4E) 		3 LYS A 131
TRP A 132
SER A 178
 None
 1.28A 5nwwA-2wmcA:
undetectable		 5nwwA-2wmcA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y3a PHOSPHATIDYLINOSITOL
-4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT BETA ISOFORM

(Mus musculus) 		PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B) 		3 LYS A 922
TRP A 878
SER A 851
 None
None
GD9  A2058 ( 4.5A)
 1.23A 5nwwA-2y3aA:
undetectable		 5nwwA-2y3aA:
3.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yev CYTOCHROME C OXIDASE
POLYPEPTIDE I+III

(Thermus
thermophilus) 		PF00115
(COX1)
PF00510
(COX3) 		3 LYS A 190
TRP A 196
SER A 187
 None
 1.34A 5nwwA-2yevA:
undetectable		 5nwwA-2yevA:
3.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ayx MEMBRANE-BOUND
HYDROGENASE LARGE
SUBUNIT

(Hydrogenovibrio
marinus) 		PF00374
(NiFeSe_Hases) 		3 LYS A 503
TRP A 504
SER A 508
 None
 1.31A 5nwwA-3ayxA:
undetectable		 5nwwA-3ayxA:
4.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2

(Homo sapiens) 		PF06920
(DHR-2) 		3 LYS A1252
TRP A1253
SER A1254
 None
 1.40A 5nwwA-3b13A:
undetectable		 5nwwA-3b13A:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cuc PROTEIN OF UNKNOWN
FUNCTION WITH A FIC
DOMAIN

(Bacteroides
thetaiotaomicron) 		PF02661
(Fic) 		3 LYS A  12
TRP A  13
SER A  15
 None
 0.99A 5nwwA-3cucA:
undetectable		 5nwwA-3cucA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0g LEUKEMIA INHIBITORY
FACTOR RECEPTOR

(Homo sapiens) 		PF00041
(fn3) 		3 LYS A 470
TRP A 471
SER A 469
 None
 1.17A 5nwwA-3e0gA:
undetectable		 5nwwA-3e0gA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbz KINASE, CMGC CDK

(Giardia
intestinalis) 		PF00069
(Pkinase) 		3 LYS A 251
TRP A 250
SER A 253
 None
 1.21A 5nwwA-3gbzA:
undetectable		 5nwwA-3gbzA:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3goh ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Shewanella
oneidensis) 		PF08240
(ADH_N) 		3 LYS A  92
TRP A  55
SER A  90
 None
 1.14A 5nwwA-3gohA:
undetectable		 5nwwA-3gohA:
7.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hei EPHRIN-A1

(Homo sapiens) 		PF00812
(Ephrin) 		3 LYS B 103
TRP B  90
SER B 105
 None
 1.16A 5nwwA-3heiB:
undetectable		 5nwwA-3heiB:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hty HYPOTHETICAL PROTEIN
BT_0869

(Bacteroides
thetaiotaomicron) 		PF12702
(Lipocalin_3) 		3 LYS A  44
TRP A  64
SER A  28
 None
 1.22A 5nwwA-3htyA:
undetectable		 5nwwA-3htyA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3if8 PROTEIN ZWILCH
HOMOLOG

(Homo sapiens) 		PF09817
(Zwilch) 		3 LYS B 530
TRP B 531
SER B 549
 None
 1.33A 5nwwA-3if8B:
undetectable		 5nwwA-3if8B:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3js8 CHOLESTEROL OXIDASE

(Chromobacterium
sp. DS-1) 		PF01565
(FAD_binding_4)
PF09129
(Chol_subst-bind) 		3 LYS A 480
TRP A 490
SER A 479
 None
None
FAD  A 541 ( 4.0A)
 1.05A 5nwwA-3js8A:
undetectable		 5nwwA-3js8A:
6.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1u BETA-XYLOSIDASE,
FAMILY 43 GLYCOSYL
HYDROLASE

(Clostridium
acetobutylicum) 		PF04616
(Glyco_hydro_43) 		3 LYS A 190
TRP A 193
SER A 214
 EDO  A 405 (-2.7A)
EDO  A 403 ( 4.3A)
None
 1.27A 5nwwA-3k1uA:
undetectable		 5nwwA-3k1uA:
7.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k77 DNA REPAIR PROTEIN
XRCC1

(Homo sapiens) 		PF01834
(XRCC1_N) 		3 LYS A  32
TRP A  33
SER A 145
 None
 1.36A 5nwwA-3k77A:
undetectable		 5nwwA-3k77A:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3la4 UREASE

(Canavalia
ensiformis) 		PF00449
(Urease_alpha)
PF00547
(Urease_gamma)
PF00699
(Urease_beta)
PF01979
(Amidohydro_1) 		3 LYS A 709
TRP A 708
SER A 711
 None
 1.05A 5nwwA-3la4A:
undetectable		 5nwwA-3la4A:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqj MLL1 PHD3-BROMO

(Homo sapiens) 		PF00628
(PHD) 		3 LYS A1773
TRP A1777
SER A1770
 None
 1.39A 5nwwA-3lqjA:
undetectable		 5nwwA-3lqjA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mx3 SUSD HOMOLOG

(Bacteroides
fragilis) 		PF12771
(SusD-like_2) 		3 LYS A 189
TRP A 190
SER A 188
 CL  A 603 ( 4.0A)
None
CL  A 603 (-3.2A)
 1.36A 5nwwA-3mx3A:
undetectable		 5nwwA-3mx3A:
5.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r0z D-SERINE DEHYDRATASE

(Salmonella
enterica) 		PF00291
(PALP) 		3 LYS A 105
TRP A 420
SER A 107
 EDO  A 452 (-3.3A)
None
None
 1.31A 5nwwA-3r0zA:
undetectable		 5nwwA-3r0zA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s48 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H

(Staphylococcus
aureus) 		PF05031
(NEAT) 		3 LYS A 157
TRP A 156
SER A  89
 None
 1.07A 5nwwA-3s48A:
undetectable		 5nwwA-3s48A:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ss7 D-SERINE DEHYDRATASE

(Escherichia
coli) 		PF00291
(PALP) 		3 LYS X 107
TRP X 422
SER X 109
 None
 1.34A 5nwwA-3ss7X:
undetectable		 5nwwA-3ss7X:
6.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3syj ADHESION AND
PENETRATION PROTEIN
AUTOTRANSPORTER

(Haemophilus
influenzae) 		PF02395
(Peptidase_S6)
PF03212
(Pertactin) 		3 LYS A 420
TRP A 419
SER A 397
 None
 1.34A 5nwwA-3syjA:
undetectable		 5nwwA-3syjA:
2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t5t PUTATIVE
GLYCOSYLTRANSFERASE

(Streptomyces
hygroscopicus) 		PF00982
(Glyco_transf_20) 		3 LYS A  11
TRP A  50
SER A  53
 MG  A 500 (-3.1A)
None
None
 0.84A 5nwwA-3t5tA:
undetectable		 5nwwA-3t5tA:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t9p MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Roseovarius sp.
TM1035) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LYS A 167
TRP A 168
SER A 139
 None
 1.32A 5nwwA-3t9pA:
undetectable		 5nwwA-3t9pA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tc2 KUNITZ-TYPE
PROTEINASE INHIBITOR
P1H5

(Solanum
tuberosum) 		PF00197
(Kunitz_legume) 		3 LYS A 104
TRP A 103
SER A 129
 None
 1.35A 5nwwA-3tc2A:
undetectable		 5nwwA-3tc2A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v96 METALLOPROTEINASE
INHIBITOR 1

(Homo sapiens) 		PF00965
(TIMP) 		3 LYS A 157
TRP A 147
SER A 155
 PO4  A 202 (-4.0A)
None
None
 1.19A 5nwwA-3v96A:
undetectable		 5nwwA-3v96A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vkg DYNEIN HEAVY CHAIN,
CYTOPLASMIC

(Dictyostelium
discoideum) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		3 LYS A4635
TRP A4671
SER A4636
 None
 1.21A 5nwwA-3vkgA:
undetectable		 5nwwA-3vkgA:
1.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w4u HEMOGLOBIN SUBUNIT
ZETA

(Homo sapiens) 		PF00042
(Globin) 		3 LYS A  71
TRP A  14
SER A  72
 None
 1.31A 5nwwA-3w4uA:
undetectable		 5nwwA-3w4uA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cz2 RAS-RELATED PROTEIN
RAB-32

(Homo sapiens) 		PF00071
(Ras) 		3 LYS A 119
TRP A 120
SER A 122
 None
 1.21A 5nwwA-4cz2A:
undetectable		 5nwwA-4cz2A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exk MALTOSE-BINDING
PERIPLASMIC PROTEIN,
UNCHARACTERIZED
PROTEIN CHIMERA

(Escherichia
coli;
Salmonella
enterica) 		PF13416
(SBP_bac_8)
PF16583
(ZirS_C) 		3 LYS A 422
TRP A 425
SER A 449
 None
 1.32A 5nwwA-4exkA:
undetectable		 5nwwA-4exkA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fc3 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H

(Staphylococcus
aureus) 		PF05031
(NEAT) 		3 LYS E  77
TRP E  76
SER E   9
 None
 1.29A 5nwwA-4fc3E:
undetectable		 5nwwA-4fc3E:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fqj HEMAGGLUTININ

(Influenza B
virus) 		PF00509
(Hemagglutinin) 		3 LYS A 269
TRP A 271
SER A 120
 None
 0.97A 5nwwA-4fqjA:
undetectable		 5nwwA-4fqjA:
7.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g7e UREASE

(Cajanus cajan) 		PF00449
(Urease_alpha)
PF00547
(Urease_gamma)
PF00699
(Urease_beta)
PF01979
(Amidohydro_1) 		3 LYS B 709
TRP B 708
SER B 711
 None
 1.06A 5nwwA-4g7eB:
undetectable		 5nwwA-4g7eB:
4.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ged ASCORBATE PEROXIDASE

(Leishmania
major) 		PF00141
(peroxidase) 		3 LYS A 297
TRP A 144
SER A  34
 None
 0.98A 5nwwA-4gedA:
undetectable		 5nwwA-4gedA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hsu LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1B

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM)
PF07496
(zf-CW) 		3 LYS A 115
TRP A 117
SER A 119
 None
 1.38A 5nwwA-4hsuA:
undetectable		 5nwwA-4hsuA:
3.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hxe PUTATIVE
UNCHARACTERIZED
PROTEIN PH0594

(Pyrococcus
horikoshii) 		PF00326
(Peptidase_S9)
PF07676
(PD40) 		3 LYS B 206
TRP B 205
SER B 182
 None
 1.10A 5nwwA-4hxeB:
undetectable		 5nwwA-4hxeB:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H

(Staphylococcus
aureus) 		PF05031
(NEAT) 		3 LYS E 397
TRP E 396
SER E 329
 None
 1.29A 5nwwA-4ij2E:
undetectable		 5nwwA-4ij2E:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0v TEK TYROSINE KINASE
VARIANT

(Homo sapiens) 		PF00041
(fn3)
PF10430
(Ig_Tie2_1) 		3 LYS A  95
TRP A  88
SER A  94
 None
 1.35A 5nwwA-4k0vA:
undetectable		 5nwwA-4k0vA:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcc BETA-2-MICROGLOBULIN
, MHC CLASS
I-RELATED PROTEIN

(Bos taurus) 		PF00129
(MHC_I)
PF07654
(C1-set) 		3 LYS C  57
TRP C  59
SER C  56
 None
 1.37A 5nwwA-4lccC:
undetectable		 5nwwA-4lccC:
8.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lr4 HYPOTHETICAL PROTEIN

([Eubacterium]
rectale) 		no annotation 3 LYS A 267
TRP A 268
SER A 374
 None
 1.29A 5nwwA-4lr4A:
undetectable		 5nwwA-4lr4A:
5.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4npr XYLOGLUCAN-SPECIFIC
ENDO-BETA-1,4-GLUCAN
ASE GH12

(Aspergillus
niveus) 		PF01670
(Glyco_hydro_12) 		3 LYS A 104
TRP A 103
SER A 187
 None
 1.01A 5nwwA-4nprA:
undetectable		 5nwwA-4nprA:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pib INCLUSION BODY
PROTEIN

(Burkholderia
thailandensis) 		PF12306
(PixA) 		3 LYS A 182
TRP A 183
SER A  50
 None
 1.38A 5nwwA-4pibA:
undetectable		 5nwwA-4pibA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ps6 INHIBITOR OF
VERTEBRATE LYSOZYME

(Pseudomonas
aeruginosa) 		PF08816
(Ivy) 		3 LYS A  55
TRP A  56
SER A  58
 None
 1.24A 5nwwA-4ps6A:
undetectable		 5nwwA-4ps6A:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rt6 HEMOPEXIN

(Oryctolagus
cuniculus) 		PF00045
(Hemopexin) 		3 LYS B  54
TRP B  53
SER B  55
 None
 1.21A 5nwwA-4rt6B:
undetectable		 5nwwA-4rt6B:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w4t MXAA

(Stigmatella
aurantiaca) 		PF07993
(NAD_binding_4) 		3 LYS A1315
TRP A1316
SER A1314
 None
 1.29A 5nwwA-4w4tA:
undetectable		 5nwwA-4w4tA:
8.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e02 FRQ-INTERACTING RNA
HELICASE

(Neurospora
crassa) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF08148
(DSHCT)
PF13234
(rRNA_proc-arch) 		3 LYS A1093
TRP A1037
SER A1092
 None
 1.34A 5nwwA-5e02A:
undetectable		 5nwwA-5e02A:
4.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e4q CONTACTIN-3

(Mus musculus) 		PF00041
(fn3) 		3 LYS A 829
TRP A 828
SER A 831
 None
 1.15A 5nwwA-5e4qA:
undetectable		 5nwwA-5e4qA:
7.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ful PROTEIN ARGININE
N-METHYLTRANSFERASE
2

(Mus musculus) 		PF05175
(MTS) 		3 LYS A 273
TRP A 277
SER A 272
 None
 0.87A 5nwwA-5fulA:
undetectable		 5nwwA-5fulA:
5.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gva WD REPEAT AND
HMG-BOX DNA-BINDING
PROTEIN 1

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		3 LYS A 200
TRP A 194
SER A 198
 None
 1.33A 5nwwA-5gvaA:
undetectable		 5nwwA-5gvaA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9x BETA-1,3-GLUCANASE

(Paenibacillus
barengoltzii) 		PF16483
(Glyco_hydro_64) 		3 LYS A 181
TRP A 133
SER A 183
 None
 0.99A 5nwwA-5h9xA:
undetectable		 5nwwA-5h9xA:
5.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hot INTEGRASE

(Human
immunodeficiency
virus 1) 		PF00552
(IN_DBD_C)
PF00665
(rve) 		3 LYS A  56
TRP A  61
SER A  57
 None
 1.40A 5nwwA-5hotA:
undetectable		 5nwwA-5hotA:
7.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ihr PROBABLE
BETA-GALACTOSIDASE A

(Aspergillus
niger) 		PF01301
(Glyco_hydro_35)
PF10435
(BetaGal_dom2)
PF13363
(BetaGal_dom3)
PF13364
(BetaGal_dom4_5) 		3 LYS A 673
TRP A 677
SER A 671
 None
 1.19A 5nwwA-5ihrA:
undetectable		 5nwwA-5ihrA:
4.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k8d COAGULATION FACTOR
VIII

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07732
(Cu-oxidase_3) 		3 LYS A  47
TRP A 208
SER A  13
 None
 1.30A 5nwwA-5k8dA:
undetectable		 5nwwA-5k8dA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kpg PAVINE
N-METHYLTRANSFERASE

(Thalictrum
flavum) 		PF02353
(CMAS) 		3 LYS A 293
TRP A 295
SER A 335
 None
 1.26A 5nwwA-5kpgA:
undetectable		 5nwwA-5kpgA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l6q H5AL

(Homo sapiens) 		PF07686
(V-set) 		3 LYS A  49
TRP A  33
SER A  30
 None
 1.06A 5nwwA-5l6qA:
undetectable		 5nwwA-5l6qA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm8 'MULTICOPPER OXIDASE

(Aspergillus
niger) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 LYS A 404
TRP A 553
SER A 402
 None
 1.19A 5nwwA-5lm8A:
undetectable		 5nwwA-5lm8A:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m23 WD REPEAT-CONTAINING
PROTEIN 5

(Homo sapiens) 		PF00400
(WD40) 		3 LYS A 120
TRP A 114
SER A 118
 None
 1.24A 5nwwA-5m23A:
undetectable		 5nwwA-5m23A:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m30 TYPE VI SECRETION
PROTEIN

(Escherichia
coli) 		PF05936
(T6SS_VasE) 		3 LYS A 145
TRP A 125
SER A 127
 None
 1.37A 5nwwA-5m30A:
undetectable		 5nwwA-5m30A:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me5 EUKARYOTIC
TRANSCRIPTION
INITIATION FACTOR 4E

(Cucumis melo) 		PF01652
(IF4E) 		3 LYS A 138
TRP A 139
SER A 185
 None
 1.30A 5nwwA-5me5A:
undetectable		 5nwwA-5me5A:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5me6 EUKARYOTIC
TRANSCRIPTION
INITIATION FACTOR 4E

(Cucumis melo) 		PF01652
(IF4E) 		3 LYS A 138
TRP A 139
SER A 185
 LYS  A 138 ( 0.0A)
TRP  A 139 ( 0.5A)
SER  A 185 ( 0.0A)
 1.13A 5nwwA-5me6A:
undetectable		 5nwwA-5me6A:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC

(Vibrio cholerae) 		PF05943
(VipB) 		3 LYS A 223
TRP A 224
SER A 226
 None
 1.12A 5nwwA-5myuA:
undetectable		 5nwwA-5myuA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nec TONB-DEPENDENT
SIDEROPHORE RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 LYS A 487
TRP A 486
SER A 493
 None
 1.23A 5nwwA-5necA:
undetectable		 5nwwA-5necA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nvm EUKARYOTIC
TRANSLATION
INITIATION FACTOR 4E
TYPE 2

(Homo sapiens) 		PF01652
(IF4E) 		3 LYS A 134
TRP A 135
SER A 181
 None
 1.00A 5nwwA-5nvmA:
undetectable		 5nwwA-5nvmA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o03 NANOBODY (VHH)
NANO-32

(Norwalk virus) 		PF07686
(V-set) 		3 LYS C 120
TRP C 125
SER C 118
 None
 1.36A 5nwwA-5o03C:
undetectable		 5nwwA-5o03C:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		3 LYS T2827
TRP T2828
SER T2830
 None
 1.39A 5nwwA-5ojsT:
undetectable		 5nwwA-5ojsT:
1.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5svb ACETONE CARBOXYLASE
GAMMA SUBUNIT

(Xanthobacter
autotrophicus) 		PF08882
(Acetone_carb_G) 		3 LYS C  69
TRP C  70
SER C  67
 None
 1.30A 5nwwA-5svbC:
undetectable		 5nwwA-5svbC:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1s SEPARIN

(Saccharomyces
cerevisiae) 		PF03568
(Peptidase_C50) 		3 LYS A 975
TRP A 973
SER A 978
 None
 1.24A 5nwwA-5u1sA:
undetectable		 5nwwA-5u1sA:
2.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5urp TOXIN 2A

(Paenibacillus
larvae) 		no annotation 3 LYS A  23
TRP A  22
SER A  20
 None
 1.18A 5nwwA-5urpA:
undetectable		 5nwwA-5urpA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wsg PRE-MRNA-SPLICING
FACTOR
CLF1,PRE-MRNA-SPLICI
NG FACTOR CLF1,CLF1

(Saccharomyces
cerevisiae) 		no annotation 3 LYS d 158
TRP d 159
SER d 161
 None
 0.62A 5nwwA-5wsgd:
undetectable		 5nwwA-5wsgd:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xd0 GLUCANASE

(Paenibacillus
sp. X4) 		PF01270
(Glyco_hydro_8) 		3 LYS A  65
TRP A  66
SER A  68
 None
 1.30A 5nwwA-5xd0A:
undetectable		 5nwwA-5xd0A:
8.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y10 MEMBRANE
GLYCOPROTEIN
POLYPROTEIN

(SFTS
phlebovirus) 		PF07243
(Phlebovirus_G1) 		3 LYS C 113
TRP C 141
SER C 115
 None
 1.15A 5nwwA-5y10C:
undetectable		 5nwwA-5y10C:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z9s GLYCOSYL HYDROLASE
FAMILY 3 PROTEIN

(Bifidobacterium
longum) 		no annotation 3 LYS A 563
TRP A 594
SER A 562
 None
 1.38A 5nwwA-5z9sA:
undetectable		 5nwwA-5z9sA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6az1 RIBOSOMAL PROTEIN
S7E

(Leishmania
donovani) 		no annotation 3 LYS I 154
TRP I 143
SER I 185
 None
 1.28A 5nwwA-6az1I:
undetectable		 5nwwA-6az1I:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9z SULFATE TRANSPORTER
CYSZ

(Pseudomonas
denitrificans
(nomen
rejiciendum)) 		no annotation 3 LYS F 199
TRP F 201
SER F 198
 None
 1.03A 5nwwA-6d9zF:
undetectable		 5nwwA-6d9zF:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gzp NANOBODY

(Lama glama) 		no annotation 3 LYS A 100
TRP A 103
SER A 100
 None
 1.10A 5nwwA-6gzpA:
undetectable		 5nwwA-6gzpA:
undetectable