SIMILAR PATTERNS OF AMINO ACIDS FOR 5NWV_A_ACAA18_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6z CHITINASE B

(Serratia
marcescens) 		PF00704
(Glyco_hydro_18) 		4 LEU A  58
ALA A  61
LEU A  52
TRP A  62
 None
 1.08A 5nwvA-1e6zA:
0.0		 5nwvA-1e6zA:
6.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hrd GLUTAMATE
DEHYDROGENASE

([Clostridium]
symbiosum) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 GLN A 404
ASP A 399
ALA A 395
LEU A 203
 None
 1.09A 5nwvA-1hrdA:
0.0		 5nwvA-1hrdA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js4 ENDO/EXOCELLULASE E4

(Thermobifida
fusca) 		PF00759
(Glyco_hydro_9)
PF00942
(CBM_3) 		4 LEU A 251
TRP A 287
ALA A 284
LEU A 288
 None
 1.11A 5nwvA-1js4A:
0.0		 5nwvA-1js4A:
5.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nr0 ACTIN INTERACTING
PROTEIN 1

(Caenorhabditis
elegans) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 LEU A 590
ALA A 552
LEU A 551
TRP A 563
 None
 0.88A 5nwvA-1nr0A:
0.0		 5nwvA-1nr0A:
4.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p7n GAG POLYPROTEIN
CAPSID PROTEIN P27

(Rous sarcoma
virus) 		no annotation 4 LEU A  68
ASP A  71
TRP A  73
LEU A  77
 None
 1.03A 5nwvA-1p7nA:
0.0		 5nwvA-1p7nA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ttx ONCOMODULIN

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 LEU A   7
ASP A  10
ALA A  13
LEU A  16
 None
 1.10A 5nwvA-1ttxA:
0.0		 5nwvA-1ttxA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvg CDP-GLUCOSE
4,6-DEHYDRATASE

(Salmonella
enterica) 		PF16363
(GDP_Man_Dehyd) 		4 ASP A 268
ALA A 271
LEU A 324
TRP A 234
 None
 1.04A 5nwvA-1wvgA:
0.0		 5nwvA-1wvgA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9d ENDOPLASMIC
RETICULUM
MANNOSYL-OLIGOSACCHA
RIDE
1,2-ALPHA-MANNOSIDAS
E

(Homo sapiens) 		PF01532
(Glyco_hydro_47) 		4 GLN A 402
ASP A 486
ALA A 490
LEU A 438
 None
 1.04A 5nwvA-1x9dA:
0.0		 5nwvA-1x9dA:
6.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9n DNA LIGASE I

(Homo sapiens) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 GLN A 457
LEU A 460
ALA A 466
LEU A 469
 None
 1.09A 5nwvA-1x9nA:
0.0		 5nwvA-1x9nA:
4.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xls ORPHAN NUCLEAR
RECEPTOR NR1I3

(Mus musculus) 		PF00104
(Hormone_recep) 		4 GLN E 144
ASP E 173
ALA E 172
LEU E 353
 None
None
TCD  E 805 ( 4.3A)
TCD  E 805 (-4.2A)
 1.05A 5nwvA-1xlsE:
undetectable		 5nwvA-1xlsE:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqq XANTHOSINE
PHOSPHORYLASE

(Escherichia
coli) 		PF01048
(PNP_UDP_1) 		4 GLN A  42
LEU A  39
ALA A 258
LEU A 260
 None
 1.03A 5nwvA-1yqqA:
undetectable		 5nwvA-1yqqA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1w TRICORN PROTEASE
INTERACTING FACTOR
F3

(Thermoplasma
acidophilum) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		4 LEU A 511
ASP A 514
ALA A 517
LEU A 520
 None
 1.10A 5nwvA-1z1wA:
undetectable		 5nwvA-1z1wA:
3.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aie PEPTIDE DEFORMYLASE

(Streptococcus
pneumoniae) 		PF01327
(Pep_deformylase) 		4 GLN P  76
LEU P  72
ALA P 106
LEU P 104
 SB9  P 501 ( 2.7A)
None
None
None
 1.05A 5nwvA-2aieP:
undetectable		 5nwvA-2aieP:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ev2 HYPOTHETICAL PROTEIN
RV1264/MT1302

(Mycobacterium
tuberculosis) 		PF16701
(Ad_Cy_reg) 		4 GLN A 173
LEU A 170
ALA A 164
LEU A 161
 None
 1.08A 5nwvA-2ev2A:
undetectable		 5nwvA-2ev2A:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fmt METHIONYL-TRNA FMET
FORMYLTRANSFERASE

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 GLN A 140
LEU A 104
ASP A  83
LEU A  80
 None
 0.86A 5nwvA-2fmtA:
undetectable		 5nwvA-2fmtA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0b FEEM

(uncultured
bacterium) 		no annotation 4 GLN A 183
LEU A 175
ALA A  93
LEU A  72
 None
 1.11A 5nwvA-2g0bA:
undetectable		 5nwvA-2g0bA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2juh TELOMERE BINDING
PROTEIN TBP1

(Nicotiana
glutinosa) 		PF00249
(Myb_DNA-binding) 		4 GLN A 644
LEU A 647
ALA A 653
TRP A 657
 None
 1.05A 5nwvA-2juhA:
undetectable		 5nwvA-2juhA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kc7 BFR218_PROTEIN

(Bacteroides
fragilis) 		PF00515
(TPR_1) 		4 GLN A  52
LEU A  55
ALA A  61
LEU A  64
 None
 1.08A 5nwvA-2kc7A:
undetectable		 5nwvA-2kc7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kr0 PROTEASOMAL
UBIQUITIN RECEPTOR
ADRM1

(Homo sapiens) 		PF04683
(Proteasom_Rpn13)
PF16550
(RPN13_C) 		4 GLN A 157
LEU A 156
ALA A 149
LEU A 150
 None
 1.11A 5nwvA-2kr0A:
undetectable		 5nwvA-2kr0A:
5.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mqd UNCHARACTERIZED
PROTEIN

(Lactobacillus
reuteri) 		no annotation 4 GLN A 123
ASP A 129
ALA A 132
LEU A 134
 None
 0.90A 5nwvA-2mqdA:
undetectable		 5nwvA-2mqdA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nq2 HYPOTHETICAL ABC
TRANSPORTER PERMEASE
PROTEIN HI1471

(Haemophilus
influenzae) 		PF01032
(FecCD) 		4 LEU A 295
ASP A 298
ALA A 301
LEU A 304
 None
 1.06A 5nwvA-2nq2A:
undetectable		 5nwvA-2nq2A:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r6i UNCHARACTERIZED
PROTEIN ATU1473

(Agrobacterium
fabrum) 		PF07542
(ATP12) 		4 GLN A 232
ASP A 227
ALA A 220
LEU A 221
 None
 1.07A 5nwvA-2r6iA:
undetectable		 5nwvA-2r6iA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r98 PUTATIVE
ACETYLGLUTAMATE
SYNTHASE

(Neisseria
gonorrhoeae) 		PF00583
(Acetyltransf_1)
PF00696
(AA_kinase) 		4 GLN A  52
LEU A  49
ASP A  46
LEU A  40
 None
 1.09A 5nwvA-2r98A:
undetectable		 5nwvA-2r98A:
7.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vd3 ATP
PHOSPHORIBOSYLTRANSF
ERASE

(Methanothermobacter
thermautotrophicus) 		PF01634
(HisG)
PF08029
(HisG_C) 		4 LEU A 159
ASP A 158
ALA A  97
LEU A 155
 None
MG  A1294 (-2.9A)
None
None
 1.05A 5nwvA-2vd3A:
undetectable		 5nwvA-2vd3A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1z ROP2

(Toxoplasma
gondii) 		PF14531
(Kinase-like) 		4 GLN A 388
LEU A 391
ALA A 397
LEU A 400
 None
 1.10A 5nwvA-2w1zA:
undetectable		 5nwvA-2w1zA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2whn PILUS ASSEMBLY
PROTEIN PILC

(Thermus
thermophilus) 		PF00482
(T2SSF) 		4 LEU A 146
ASP A 149
ALA A 152
LEU A 155
 None
 0.90A 5nwvA-2whnA:
undetectable		 5nwvA-2whnA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xhs NUCLEAR HORMONE
RECEPTOR FTZ-F1

(Drosophila
melanogaster) 		PF00104
(Hormone_recep) 		4 GLN A 844
LEU A 841
ASP A 838
LEU A 832
 None
 1.09A 5nwvA-2xhsA:
undetectable		 5nwvA-2xhsA:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yqy HYPOTHETICAL PROTEIN
TTHA0303

(Thermus
thermophilus) 		PF12867
(DinB_2) 		4 LEU A  56
ASP A  59
ALA A  62
LEU A  65
 None
 0.94A 5nwvA-2yqyA:
undetectable		 5nwvA-2yqyA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yzr PYRIDOXAL
BIOSYNTHESIS LYASE
PDXS

(Methanocaldococcus
jannaschii) 		PF01680
(SOR_SNZ)
PF05690
(ThiG) 		4 GLN A 262
LEU A 259
ASP A 256
LEU A 307
 None
 0.95A 5nwvA-2yzrA:
undetectable		 5nwvA-2yzrA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z0f PUTATIVE
PHOSPHOGLUCOMUTASE

(Thermus
thermophilus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A  74
TRP A  79
ALA A  80
LEU A  83
 None
 1.01A 5nwvA-2z0fA:
undetectable		 5nwvA-2z0fA:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zc8 N-ACYLAMINO ACID
RACEMASE

(Thermus
thermophilus) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASP A 109
TRP A 111
ALA A 112
LEU A 115
 None
 1.06A 5nwvA-2zc8A:
undetectable		 5nwvA-2zc8A:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zvf ALANYL-TRNA
SYNTHETASE

(Archaeoglobus
fulgidus) 		PF02272
(DHHA1) 		4 ASP A 792
TRP A 794
ALA A 791
LEU A 825
 None
 0.99A 5nwvA-2zvfA:
undetectable		 5nwvA-2zvfA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ay0 UNCHARACTERIZED
PROTEIN MJ0883

(Methanocaldococcus
jannaschii) 		PF02475
(Met_10) 		4 LEU A 312
ASP A 330
ALA A 328
LEU A 327
 None
 1.11A 5nwvA-3ay0A:
undetectable		 5nwvA-3ay0A:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bdz P450CIN

(Citrobacter
braakii) 		PF00067
(p450) 		4 LEU A 237
ASP A 241
ALA A 244
LEU A 247
 MLI  A 500 ( 4.5A)
None
None
None
 1.07A 5nwvA-3bdzA:
undetectable		 5nwvA-3bdzA:
8.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dla GLUTAMINE-DEPENDENT
NAD(+) SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00795
(CN_hydrolase)
PF02540
(NAD_synthase) 		4 LEU A 571
ASP A 568
TRP A 592
ALA A 565
 None
 1.12A 5nwvA-3dlaA:
undetectable		 5nwvA-3dlaA:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epj TRNA
ISOPENTENYLTRANSFERA
SE

(Saccharomyces
cerevisiae) 		PF01715
(IPPT) 		4 ASP A 316
TRP A 323
ALA A 317
LEU A 320
 None
MG  A   5 ( 4.2A)
None
None
 1.05A 5nwvA-3epjA:
undetectable		 5nwvA-3epjA:
6.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g1w SUGAR ABC
TRANSPORTER

(Bacillus
halodurans) 		PF13407
(Peripla_BP_4) 		4 GLN A 180
LEU A 177
ALA A 107
LEU A 113
 None
 1.06A 5nwvA-3g1wA:
undetectable		 5nwvA-3g1wA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g5w MULTICOPPER OXIDASE
TYPE 1

(Nitrosomonas
europaea) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 LEU A 184
TRP A 189
ALA A 214
LEU A  59
 None
 0.72A 5nwvA-3g5wA:
undetectable		 5nwvA-3g5wA:
7.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3h00 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00517
(GP41) 		4 GLN A  23
LEU A  26
ASP A  29
ALA A  32
 None
 0.91A 5nwvA-3h00A:
undetectable		 5nwvA-3h00A:
54.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3icv LIPASE B

(Moesziomyces
antarcticus) 		no annotation 4 GLN A 191
LEU A 143
ALA A 164
LEU A 136
 None
 0.99A 5nwvA-3icvA:
undetectable		 5nwvA-3icvA:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k9a HIV GLYCOPROTEIN
GP41

(Human
immunodeficiency
virus 1) 		PF00517
(GP41) 		4 LEU A  80
ASP A  83
TRP A  85
ALA A  86
 None
 0.42A 5nwvA-3k9aA:
undetectable		 5nwvA-3k9aA:
28.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khk TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLATION SUBUNIT

(Methanosarcina
mazei) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 GLN A 503
ASP A 463
ALA A 424
LEU A 425
 None
 1.01A 5nwvA-3khkA:
undetectable		 5nwvA-3khkA:
6.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2p DNA LIGASE 3

(Homo sapiens) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		4 GLN A 197
ASP A 344
ALA A 350
LEU A 384
 None
 0.82A 5nwvA-3l2pA:
undetectable		 5nwvA-3l2pA:
5.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4k DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF16898
(TOPRIM_C) 		4 GLN A1167
LEU A1170
ASP A1173
ALA A1176
 None
 0.84A 5nwvA-3l4kA:
undetectable		 5nwvA-3l4kA:
4.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lfu DNA HELICASE II

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		4 LEU A 114
ASP A 188
ALA A 190
LEU A 193
 None
 0.89A 5nwvA-3lfuA:
undetectable		 5nwvA-3lfuA:
4.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3llc PUTATIVE HYDROLASE

(Agrobacterium
vitis) 		PF12697
(Abhydrolase_6) 		4 LEU A  55
ASP A  58
ALA A  61
LEU A  64
 EDO  A 275 ( 4.2A)
None
None
None
 0.93A 5nwvA-3llcA:
undetectable		 5nwvA-3llcA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lom GERANYLTRANSTRANSFER
ASE

(Legionella
pneumophila) 		PF00348
(polyprenyl_synt) 		4 GLN A  73
LEU A  76
ALA A  82
LEU A  85
 None
 1.06A 5nwvA-3lomA:
undetectable		 5nwvA-3lomA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poy NEUREXIN-1-ALPHA

(Bos taurus) 		PF00008
(EGF)
PF02210
(Laminin_G_2) 		4 GLN A 955
ASP A1080
ALA A 774
LEU A 794
 None
 1.09A 5nwvA-3poyA:
undetectable		 5nwvA-3poyA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rim TRANSKETOLASE

(Mycobacterium
tuberculosis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 333
ASP A 336
TRP A 338
ALA A 339
 None
 0.88A 5nwvA-3rimA:
undetectable		 5nwvA-3rimA:
3.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rkg MAGNESIUM
TRANSPORTER MRS2,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		no annotation 4 GLN A 228
LEU A 225
ASP A 222
LEU A 216
 None
 1.03A 5nwvA-3rkgA:
undetectable		 5nwvA-3rkgA:
9.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ro2 G-PROTEIN-SIGNALING
MODULATOR 2

(Mus musculus) 		PF13176
(TPR_7)
PF13424
(TPR_12) 		4 LEU A  68
ASP A  70
ALA A  72
LEU A  75
 None
 0.93A 5nwvA-3ro2A:
undetectable		 5nwvA-3ro2A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3scy HYPOTHETICAL
BACTERIAL
6-PHOSPHOGLUCONOLACT
ONASE

(Bacteroides
fragilis) 		PF10282
(Lactonase) 		4 GLN A 175
LEU A 197
ALA A 194
LEU A 193
 None
 0.94A 5nwvA-3scyA:
undetectable		 5nwvA-3scyA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tul CELL INVASION
PROTEIN SIPB

(Salmonella
enterica) 		PF16535
(T3SSipB) 		4 GLN A 130
LEU A 133
ALA A 139
LEU A 142
 None
 1.07A 5nwvA-3tulA:
undetectable		 5nwvA-3tulA:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u80 3-DEHYDROQUINATE
DEHYDRATASE, TYPE II

(Bifidobacterium
longum) 		PF01220
(DHquinase_II) 		4 LEU A 137
ASP A 140
ALA A 143
LEU A 146
 None
 1.05A 5nwvA-3u80A:
undetectable		 5nwvA-3u80A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vi1 ALKALINE
METALLOPROTEINASE

(Pseudomonas
aeruginosa) 		PF08548
(Peptidase_M10_C)
PF13583
(Reprolysin_4) 		4 LEU A 235
ASP A 237
ALA A  36
LEU A  40
 None
 1.01A 5nwvA-3vi1A:
undetectable		 5nwvA-3vi1A:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4awn DEOXYRIBONUCLEASE-1

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		4 GLN A 155
LEU A 152
ASP A 149
ALA A 146
 None
 1.05A 5nwvA-4awnA:
undetectable		 5nwvA-4awnA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czd PUTATIVE
TRANSCRIPTIONAL
REGULATOR, ASNC
FAMILY

(Desulfovibrio
desulfuricans) 		PF13404
(HTH_AsnC-type)
no annotation 		4 GLN A  97
ASP A 122
TRP A 126
LEU B 144
 None
 1.11A 5nwvA-4czdA:
undetectable		 5nwvA-4czdA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d2o PER-2 BETA-LACTAMASE

(Citrobacter
freundii) 		PF13354
(Beta-lactamase2) 		4 LEU A  60
TRP A  49
ALA A 187
LEU A 260
 None
 1.05A 5nwvA-4d2oA:
undetectable		 5nwvA-4d2oA:
8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ewf BETA-LACTAMASE

(Sphaerobacter
thermophilus) 		PF13354
(Beta-lactamase2) 		4 GLN A 169
LEU A 166
ASP A 163
ALA A 159
 None
 1.08A 5nwvA-4ewfA:
undetectable		 5nwvA-4ewfA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfh DNA TOPOISOMERASE 2

(Saccharomyces
cerevisiae) 		PF00204
(DNA_gyraseB)
PF00521
(DNA_topoisoIV)
PF01751
(Toprim)
PF02518
(HATPase_c)
PF16898
(TOPRIM_C) 		4 GLN A1167
LEU A1170
ASP A1173
ALA A1176
 None
 0.88A 5nwvA-4gfhA:
undetectable		 5nwvA-4gfhA:
3.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 12

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M)
PF00662
(Proton_antipo_N) 		4 GLN L 582
LEU L 592
ALA L 597
LEU L 600
 None
 1.12A 5nwvA-4heaL:
undetectable		 5nwvA-4heaL:
4.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7m PROTEIN DOM3Z

(Mus musculus) 		PF08652
(RAI1) 		4 GLN A  32
LEU A  35
ALA A 332
LEU A 335
 UBD  A 401 (-3.0A)
None
None
None
 0.97A 5nwvA-4j7mA:
undetectable		 5nwvA-4j7mA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgh CULLIN-5

(Homo sapiens) 		PF00888
(Cullin) 		4 LEU D  43
ASP D  46
ALA D  49
TRP D  53
 None
 1.04A 5nwvA-4jghD:
undetectable		 5nwvA-4jghD:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jw1 EFFECTOR PROTEIN B

(Legionella
pneumophila) 		no annotation 4 GLN A 373
LEU A 376
ASP A 379
ALA A 382
 None
 1.02A 5nwvA-4jw1A:
undetectable		 5nwvA-4jw1A:
5.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mf9 HEMIN DEGRADING
FACTOR

(Pseudomonas
aeruginosa) 		PF05171
(HemS) 		4 ASP A  32
TRP A  18
ALA A  30
LEU A  44
 None
 1.05A 5nwvA-4mf9A:
undetectable		 5nwvA-4mf9A:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9f CULLIN-5

(Homo sapiens) 		no annotation 4 LEU U  43
ALA U  49
LEU U  52
TRP U  53
 None
 0.98A 5nwvA-4n9fU:
undetectable		 5nwvA-4n9fU:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n9f CULLIN-5

(Homo sapiens) 		no annotation 4 LEU U  43
ASP U  46
ALA U  49
TRP U  53
 None
 1.02A 5nwvA-4n9fU:
undetectable		 5nwvA-4n9fU:
8.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xrt STFQ
AROMATASE/CYCLASE

(Streptomyces
steffisburgensis) 		PF03364
(Polyketide_cyc) 		4 LEU A  21
ASP A  24
ALA A  27
LEU A  29
 None
 1.04A 5nwvA-4xrtA:
undetectable		 5nwvA-4xrtA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xxn ESX-1
SECRETION-ASSOCIATED
PROTEIN ESPB

(Mycobacterium
tuberculosis) 		no annotation 4 GLN A  48
LEU A  51
ASP A  54
LEU A  60
 None
 1.11A 5nwvA-4xxnA:
undetectable		 5nwvA-4xxnA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xyi KINETOCHORE PROTEIN
MIS16

(Schizosaccharomyces
japonicus) 		PF00400
(WD40)
PF12265
(CAF1C_H4-bd) 		4 LEU A 247
ALA A 196
LEU A 195
TRP A 207
 None
 1.11A 5nwvA-4xyiA:
undetectable		 5nwvA-4xyiA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a6c G-PROTEIN-SIGNALING
MODULATOR 2, AFADIN

(Homo sapiens) 		PF13176
(TPR_7)
PF13181
(TPR_8)
PF13424
(TPR_12) 		4 LEU A  68
ASP A  70
ALA A  72
LEU A  75
 None
 0.91A 5nwvA-5a6cA:
undetectable		 5nwvA-5a6cA:
7.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eo6 COPROPORPHYRINOGEN
OXIDASE

(Acinetobacter
baumannii) 		PF01218
(Coprogen_oxidas) 		4 GLN A 148
LEU A 151
ALA A 157
LEU A 160
 None
 1.12A 5nwvA-5eo6A:
undetectable		 5nwvA-5eo6A:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikp GLYCOGEN
PHOSPHORYLASE, BRAIN
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		4 ASP A 128
TRP A 182
ALA A 129
LEU A 131
 None
 1.09A 5nwvA-5ikpA:
undetectable		 5nwvA-5ikpA:
3.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00180
(Iso_dh) 		4 GLN A 134
LEU A  95
TRP A 119
ALA A  86
 None
 0.90A 5nwvA-5j32A:
undetectable		 5nwvA-5j32A:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjh 4-ALPHA-GLUCANOTRANS
FERASE

(Corynebacterium
glutamicum) 		PF02446
(Glyco_hydro_77) 		4 GLN A 662
LEU A 576
ALA A 566
LEU A 569
 None
 1.03A 5nwvA-5jjhA:
undetectable		 5nwvA-5jjhA:
4.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k2z PYRIDOXAL
5'-PHOSPHATE
SYNTHASE SUBUNIT
PDX1.3

(Arabidopsis
thaliana) 		PF01680
(SOR_SNZ) 		4 GLN A 242
LEU A 239
ASP A 236
LEU A 287
 None
 0.96A 5nwvA-5k2zA:
undetectable		 5nwvA-5k2zA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kij ENDOPLASMIC
RETICULUM
MANNOSYL-OLIGOSACCHA
RIDE
1,2-ALPHA-MANNOSIDAS
E

(Homo sapiens) 		PF01532
(Glyco_hydro_47) 		4 GLN A 402
ASP A 486
ALA A 490
LEU A 438
 None
 1.05A 5nwvA-5kijA:
undetectable		 5nwvA-5kijA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ks1 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Vibrio
vulnificus) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 LEU A 383
ASP A 386
ALA A 389
LEU A 392
 None
 1.02A 5nwvA-5ks1A:
undetectable		 5nwvA-5ks1A:
6.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l94 CYTOCHROME P450

(Bacillus
megaterium) 		PF00067
(p450) 		4 GLN A 375
ASP A 371
ALA A 367
LEU A 275
 None
 1.02A 5nwvA-5l94A:
undetectable		 5nwvA-5l94A:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnt PYRIDOXAL
5'-PHOSPHATE
SYNTHASE SUBUNIT
PDX1.1

(Arabidopsis
thaliana) 		PF01680
(SOR_SNZ) 		4 GLN A 243
LEU A 240
ASP A 237
LEU A 288
 None
 0.92A 5nwvA-5lntA:
undetectable		 5nwvA-5lntA:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m42 PROLINE
DEHYDROGENASE

(Thermus
thermophilus) 		PF01619
(Pro_dh) 		4 GLN A  77
LEU A  80
TRP A  85
ALA A  86
 None
 0.83A 5nwvA-5m42A:
undetectable		 5nwvA-5m42A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mio KINESIN-LIKE PROTEIN
KIF2C,KIF2C FUSED TO
A DARPIN,KIF2C FUSED
TO A DARPIN

(Homo sapiens) 		PF00023
(Ank)
PF00225
(Kinesin)
PF12796
(Ank_2) 		5 GLN C 387
LEU C 383
ASP C 380
ALA C 330
LEU C 332
 None
 1.38A 5nwvA-5mioC:
undetectable		 5nwvA-5mioC:
5.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mua RICIN B-RELATED
LECTIN

(Polyporus
squamosus) 		PF14200
(RicinB_lectin_2) 		4 GLN A 186
TRP A  49
ALA A  22
LEU A  21
 None
 1.06A 5nwvA-5muaA:
undetectable		 5nwvA-5muaA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5muw PACKAGING ENZYME P4

(Pseudomonas
virus phi6) 		PF11602
(NTPase_P4) 		4 LEU A 158
ASP A 159
ALA A  60
LEU A  59
 None
 1.12A 5nwvA-5muwA:
undetectable		 5nwvA-5muwA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nj6 PROTEINASE-ACTIVATED
RECEPTOR 2,SOLUBLE
CYTOCHROME
B562,PROTEINASE-ACTI
VATED RECEPTOR 2

(Escherichia
coli;
Homo sapiens) 		PF00001
(7tm_1)
PF07361
(Cytochrom_B562) 		4 LEU A 166
TRP A 199
ALA A 120
LEU A 119
 None
 1.04A 5nwvA-5nj6A:
undetectable		 5nwvA-5nj6A:
5.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5nwu WTFP-TAG,GP41

(Human
immunodeficiency
virus 1;
unidentified) 		no annotation 4 GLN A  22
LEU A  25
ASP A  28
ALA A  31
 ACA  A  18 ( 4.1A)
None
None
None
 1.02A 5nwvA-5nwuA:
undetectable		 5nwvA-5nwuA:
88.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o9h C5A ANAPHYLATOXIN
CHEMOTACTIC RECEPTOR
1

(Homo sapiens) 		no annotation 4 LEU A 166
TRP A 161
ALA A 122
LEU A 126
 None
 1.05A 5nwvA-5o9hA:
undetectable		 5nwvA-5o9hA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7w APYRASE

(Trifolium
repens) 		PF01150
(GDA1_CD39) 		4 GLN A 377
TRP A 136
ALA A 169
LEU A 201
 None
 1.03A 5nwvA-5u7wA:
undetectable		 5nwvA-5u7wA:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7x NOD FACTOR BINDING
LECTIN-NUCLEOTIDE
PHOSPHOHYDROLASE

(Vigna
unguiculata) 		PF01150
(GDA1_CD39) 		4 GLN F 374
TRP F 136
ALA F 169
LEU F 201
 None
 0.95A 5nwvA-5u7xF:
undetectable		 5nwvA-5u7xF:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uni NAD(P)
TRANSHYDROGENASE
SUBUNIT BETA

(Thermus
thermophilus) 		PF02233
(PNTB) 		4 GLN B 153
LEU B 196
ALA B 135
LEU B 139
 BEN  B 312 (-4.3A)
None
None
None
 1.11A 5nwvA-5uniB:
undetectable		 5nwvA-5uniB:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vey E3 UBIQUITIN-PROTEIN
LIGASE RNF169

(Homo sapiens) 		no annotation 4 GLN C 675
LEU C 672
ASP C 669
LEU C 663
 None
 1.03A 5nwvA-5veyC:
undetectable		 5nwvA-5veyC:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x87 BESTROPHIN

(Klebsiella
pneumoniae) 		no annotation 4 LEU A 250
ASP A 253
ALA A 256
LEU A 259
 None
 1.05A 5nwvA-5x87A:
undetectable		 5nwvA-5x87A:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zbb -

(-) 		no annotation 4 GLN A 307
ALA A 139
LEU A 164
TRP A 168
 None
None
None
IOD  A 601 (-4.6A)
 1.08A 5nwvA-5zbbA:
undetectable		 5nwvA-5zbbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b85 TMHC4_R

(synthetic
construct) 		no annotation 4 ASP J 181
ALA J 174
LEU J 177
TRP J 151
 None
 1.07A 5nwvA-6b85J:
undetectable		 5nwvA-6b85J:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ek7 YAXA

(Yersinia
enterocolitica) 		no annotation 4 GLN A 112
LEU A 115
ASP A 118
ALA A 121
 None
 0.91A 5nwvA-6ek7A:
undetectable		 5nwvA-6ek7A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6el1 YAXB

(Yersinia
enterocolitica) 		no annotation 4 GLN O 160
LEU O 163
ASP O 166
LEU O 172
 None
 0.86A 5nwvA-6el1O:
undetectable		 5nwvA-6el1O:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6et8 -

(-) 		no annotation 4 GLN A  25
LEU A  28
ALA A  34
LEU A  37
 None
 1.04A 5nwvA-6et8A:
undetectable		 5nwvA-6et8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k ACTF

(Rhodothermus
marinus) 		no annotation 4 GLN F  61
LEU F 367
TRP F 361
TRP F 304
 None
 1.10A 5nwvA-6f0kF:
undetectable		 5nwvA-6f0kF:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2

(Saccharomyces
cerevisiae) 		no annotation 4 GLN B  60
LEU B 514
ALA B 685
LEU B 687
 None
 1.06A 5nwvA-6f42B:
undetectable		 5nwvA-6f42B:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g2j NADH-UBIQUINONE
OXIDOREDUCTASE CHAIN
5

(Mus musculus) 		no annotation 4 GLN L 321
LEU L 394
ASP L 393
ALA L 490
 None
 1.03A 5nwvA-6g2jL:
undetectable		 5nwvA-6g2jL:
17.95