SIMILAR PATTERNS OF AMINO ACIDS FOR 5NVP_A_ACAA18_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9c SULFITE OXIDASE

(Gallus gallus) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 LEU A 449
LYS A 200
LEU A 202
TRP A 204
 None
None
SO4  A7503 (-3.8A)
SO4  A7503 (-4.5A)
 1.40A 5nvpA-2a9cA:
0.0		 5nvpA-2a9cA:
7.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g0b HYDROXYCINNAMOYL-COA
SHIKIMATE/QUINATE
HYDROXYCINNAMOYLTRAN
SFERASE

(Coffea
canephora) 		PF02458
(Transferase) 		4 LEU A 426
LYS A 268
LEU A 315
TRP A 263
 None
 1.42A 5nvpA-4g0bA:
0.0		 5nvpA-4g0bA:
5.73