SIMILAR PATTERNS OF AMINO ACIDS FOR 5NUM_A_Z80A201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8h DNA POLYMERASE
PROCESSIVITY
COMPONENT

(Escherichia
virus RB69) 		PF02916
(DNA_PPF)
PF09116
(gp45-slide_C) 		5 ILE A 149
LEU A 169
ILE A 140
ILE A 182
SER A 215
 None
 1.25A 5numA-1b8hA:
0.0		 5numA-1b8hA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhe POLYGALACTURONASE

(Pectobacterium
carotovorum) 		PF00295
(Glyco_hydro_28) 		5 ILE A 214
ILE A 204
ILE A 219
ASN A 225
MET A 253
 None
 1.49A 5numA-1bheA:
0.0		 5numA-1bheA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1byr PROTEIN
(ENDONUCLEASE)

(Salmonella
enterica) 		PF13091
(PLDc_2) 		5 ILE A  77
LEU A  46
ILE A  58
ILE A  60
ASN A  65
 None
 1.27A 5numA-1byrA:
0.0		 5numA-1byrA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c9l CLATHRIN

(Rattus
norvegicus) 		PF01394
(Clathrin_propel)
PF09268
(Clathrin-link) 		4 ILE A 335
LEU A 357
ILE A 334
ILE A 293
 None
 0.70A 5numA-1c9lA:
0.0		 5numA-1c9lA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chm CREATINE
AMIDINOHYDROLASE

(Pseudomonas
putida) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		5 ILE A  44
LEU A 136
ILE A 111
ILE A  78
SER A  61
 None
 1.26A 5numA-1chmA:
0.0		 5numA-1chmA:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cjy PROTEIN (CYTOSOLIC
PHOSPHOLIPASE A2)

(Homo sapiens) 		PF00168
(C2)
PF01735
(PLA2_B) 		5 VAL A 208
ILE A 192
LEU A 212
ILE A 572
SER A 577
 None
 1.45A 5numA-1cjyA:
0.0		 5numA-1cjyA:
7.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cvr GINGIPAIN R

(Porphyromonas
gingivalis) 		PF01364
(Peptidase_C25)
PF03785
(Peptidase_C25_C) 		5 VAL A 108
LEU A  70
ILE A  13
ILE A  15
SER A  92
 None
 1.45A 5numA-1cvrA:
0.1		 5numA-1cvrA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dkr PHOSPHORIBOSYL
PYROPHOSPHATE
SYNTHETASE

(Bacillus
subtilis) 		PF13793
(Pribosyltran_N)
PF14572
(Pribosyl_synth) 		5 VAL A 274
ILE A 264
LEU A 272
ILE A 286
SER A  65
 None
 1.31A 5numA-1dkrA:
0.0		 5numA-1dkrA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dys ENDOGLUCANASE

(Humicola
insolens) 		PF01341
(Glyco_hydro_6) 		5 VAL A 134
ILE A  53
LEU A  83
ILE A  62
SER A 168
 None
 1.42A 5numA-1dysA:
0.0		 5numA-1dysA:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dzb SCFV FRAGMENT 1F9

(Mus musculus) 		PF07686
(V-set) 		5 VAL A 219
LEU A 278
ILE A 306
MET A 211
SER A 209
 None
 1.41A 5numA-1dzbA:
undetectable		 5numA-1dzbA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6y METHYL-COENZYME M
REDUCTASE I BETA
SUBUNIT

(Methanosarcina
barkeri) 		PF02241
(MCR_beta)
PF02783
(MCR_beta_N) 		5 VAL B2153
ILE B2050
LEU B2054
ILE B2075
ILE B2082
 None
 0.91A 5numA-1e6yB:
undetectable		 5numA-1e6yB:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1esc ESTERASE

(Streptomyces
scabiei) 		PF13472
(Lipase_GDSL_2) 		5 VAL A   6
ILE A  54
LEU A  56
ILE A 300
ILE A 303
 None
 1.33A 5numA-1escA:
undetectable		 5numA-1escA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1euz GLUTAMATE
DEHYDROGENASE

(Thermococcus
profundus) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		5 VAL A 317
ILE A 196
ILE A 199
ILE A 215
SER A 243
 None
 1.06A 5numA-1euzA:
undetectable		 5numA-1euzA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnj PROTEIN (CHORISMATE
MUTASE)

(Bacillus
subtilis) 		PF07736
(CM_1) 		5 VAL A  62
LEU A  65
ILE A  31
MET A  45
SER A  48
 None
 1.45A 5numA-1fnjA:
undetectable		 5numA-1fnjA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1inp INOSITOL
POLYPHOSPHATE
1-PHOSPHATASE

(Bos taurus) 		PF00459
(Inositol_P) 		4 ILE A 374
LEU A 335
ILE A 307
ILE A 265
 None
 0.70A 5numA-1inpA:
undetectable		 5numA-1inpA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iuq GLYCEROL-3-PHOSPHATE
ACYLTRANSFERASE

(Cucurbita
moschata) 		PF01553
(Acyltransferase)
PF14829
(GPAT_N) 		5 LEU A 151
ILE A 147
ILE A 281
ASN A 301
SER A 350
 None
 1.47A 5numA-1iuqA:
undetectable		 5numA-1iuqA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iz6 INITIATION FACTOR 5A

(Pyrococcus
horikoshii) 		PF01287
(eIF-5a)
PF08207
(EFP_N) 		5 VAL A   9
ILE A  27
LEU A  12
ILE A  18
ILE A  20
 None
 1.05A 5numA-1iz6A:
undetectable		 5numA-1iz6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iz6 INITIATION FACTOR 5A

(Pyrococcus
horikoshii) 		PF01287
(eIF-5a)
PF08207
(EFP_N) 		5 VAL A   9
ILE A  45
LEU A  12
ILE A  18
ILE A  20
 None
 1.29A 5numA-1iz6A:
undetectable		 5numA-1iz6A:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jl0 S-ADENOSYLMETHIONINE
DECARBOXYLASE
PROENZYME

(Homo sapiens) 		PF01536
(SAM_decarbox) 		5 VAL A 271
ILE A 209
LEU A 212
ILE A 242
ILE A 244
 None
 1.44A 5numA-1jl0A:
2.8		 5numA-1jl0A:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kea POSSIBLE G-T
MISMATCHES REPAIR
ENZYME

(Methanothermobacter
thermautotrophicus) 		PF00730
(HhH-GPD) 		5 ILE A  43
LEU A  44
ILE A  40
ILE A  70
SER A  76
 None
 1.30A 5numA-1keaA:
undetectable		 5numA-1keaA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1khu SMAD1

(Homo sapiens) 		PF03166
(MH2) 		5 VAL A 294
ILE A 274
ILE A 438
ILE A 412
SER A 379
 None
 1.32A 5numA-1khuA:
undetectable		 5numA-1khuA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knx PROBABLE HPR(SER)
KINASE/PHOSPHATASE

(Mycoplasma
pneumoniae) 		PF02603
(Hpr_kinase_N)
PF07475
(Hpr_kinase_C) 		5 VAL A 258
ILE A 226
LEU A 189
ILE A 182
ILE A 138
 None
 1.30A 5numA-1knxA:
undetectable		 5numA-1knxA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kzh PHOSPHOFRUCTOKINASE

(Borreliella
burgdorferi) 		PF00365
(PFK) 		4 VAL A 308
ILE A 402
ILE A 288
SER A 274
 None
 0.72A 5numA-1kzhA:
undetectable		 5numA-1kzhA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l1f GLUTAMATE
DEHYDROGENASE 1

(Homo sapiens) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		5 ILE A 372
LEU A 377
ILE A 227
ILE A 231
ASN A 232
 None
 1.23A 5numA-1l1fA:
undetectable		 5numA-1l1fA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1luj CATENIN BETA-1

(Homo sapiens) 		PF00514
(Arm) 		5 VAL A 617
ILE A 631
LEU A 621
ILE A 596
SER A 605
 None
 1.14A 5numA-1lujA:
undetectable		 5numA-1lujA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9i ANNEXIN VI

(Homo sapiens) 		PF00191
(Annexin) 		5 ILE A 421
LEU A 417
ILE A 386
ILE A 387
SER A 630
 None
 1.05A 5numA-1m9iA:
undetectable		 5numA-1m9iA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mc8 FLAP ENDONUCLEASE-1

(Pyrococcus
horikoshii) 		PF00752
(XPG_N)
PF00867
(XPG_I) 		4 ILE A  73
LEU A  19
ILE A  24
ILE A  26
 None
 0.72A 5numA-1mc8A:
undetectable		 5numA-1mc8A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mi8 DNAB INTEIN

(Synechocystis
sp. PCC 6803) 		PF14890
(Intein_splicing) 		5 ILE A 123
LEU A  87
ILE A  93
ILE A 150
SER A   3
 None
 1.50A 5numA-1mi8A:
undetectable		 5numA-1mi8A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mt0 HEMOLYSIN SECRETION
ATP-BINDING PROTEIN

(Escherichia
coli) 		PF00005
(ABC_tran) 		5 ILE A 588
LEU A 591
ILE A 559
ILE A 614
SER A 640
 None
 1.15A 5numA-1mt0A:
undetectable		 5numA-1mt0A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mx3 C-TERMINAL BINDING
PROTEIN 1

(Homo sapiens) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A 115
LEU A  92
ILE A  95
ILE A 105
 None
 0.68A 5numA-1mx3A:
undetectable		 5numA-1mx3A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfg D-HYDANTOINASE

(Ralstonia
pickettii) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		5 VAL A  49
LEU A 392
ILE A  42
ILE A   3
SER A 386
 None
 1.49A 5numA-1nfgA:
undetectable		 5numA-1nfgA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nj8 PROLINE-TRNA
SYNTHETASE

(Methanocaldococcus
jannaschii) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon)
PF09181
(ProRS-C_2) 		5 VAL A 371
ILE A 349
LEU A 367
ILE A 302
ILE A 283
 None
 1.12A 5numA-1nj8A:
undetectable		 5numA-1nj8A:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nnx PROTEIN YGIW

(Escherichia
coli) 		PF04076
(BOF) 		5 ILE A  86
ILE A  99
ILE A  64
ASN A  65
SER A  51
 None
 1.39A 5numA-1nnxA:
undetectable		 5numA-1nnxA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1now BETA-HEXOSAMINIDASE
BETA CHAIN

(Homo sapiens) 		PF00728
(Glyco_hydro_20)
PF14845
(Glycohydro_20b2) 		4 ILE A 349
LEU A 351
ILE A 395
ILE A 398
 None
 0.69A 5numA-1nowA:
undetectable		 5numA-1nowA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofc ISWI PROTEIN

(Drosophila
melanogaster) 		PF09110
(HAND)
PF09111
(SLIDE) 		5 ILE X 852
LEU X 849
ILE X 855
ILE X 859
ASN X 812
 None
 1.23A 5numA-1ofcX:
undetectable		 5numA-1ofcX:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgu ACTIN INTERACTING
PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00400
(WD40) 		5 ILE A 469
LEU A 483
ILE A 503
ILE A 496
SER A 475
 None
 1.17A 5numA-1pguA:
undetectable		 5numA-1pguA:
9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgv TROPOMODULIN TMD-1

(Caenorhabditis
elegans) 		no annotation 5 VAL A 224
ILE A 254
LEU A 257
ASN A 244
MET A 246
 None
 1.40A 5numA-1pgvA:
undetectable		 5numA-1pgvA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q2l PROTEASE III

(Escherichia
coli) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF16187
(Peptidase_M16_M) 		5 ILE A 372
LEU A 376
ILE A 353
ILE A 336
SER A 319
 None
 1.29A 5numA-1q2lA:
undetectable		 5numA-1q2lA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5a EP-CADHERIN

(Mus musculus) 		PF00028
(Cadherin) 		4 VAL A 473
LEU A 513
ILE A 459
SER A 497
 None
 0.00A 5numA-1q5aA:
undetectable		 5numA-1q5aA:
7.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu2 ISOLEUCYL-TRNA
SYNTHETASE

(Staphylococcus
aureus) 		PF00133
(tRNA-synt_1)
PF06827
(zf-FPG_IleRS)
PF08264
(Anticodon_1) 		4 LEU A 760
ILE A 648
ILE A 712
SER A 691
 None
 0.72A 5numA-1qu2A:
undetectable		 5numA-1qu2A:
6.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sdd COAGULATION FACTOR V

(Bos taurus) 		PF00754
(F5_F8_type_C)
PF07732
(Cu-oxidase_3) 		5 VAL B2109
ILE B2162
LEU B2173
ILE B2095
ASN B2149
 None
 1.30A 5numA-1sddB:
undetectable		 5numA-1sddB:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tk9 PHOSPHOHEPTOSE
ISOMERASE 1

(Campylobacter
jejuni) 		PF13580
(SIS_2) 		5 VAL A  31
LEU A  35
ILE A  45
ILE A  47
SER A 144
 None
 0.96A 5numA-1tk9A:
undetectable		 5numA-1tk9A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tkc TRANSKETOLASE

(Saccharomyces
cerevisiae) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		5 ILE A 231
LEU A  44
ILE A 181
ASN A 179
SER A 147
 None
 1.44A 5numA-1tkcA:
undetectable		 5numA-1tkcA:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 1

(Streptomyces
coelicolor) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 VAL A 180
ILE A   7
LEU A 246
MET A 412
SER A 410
 None
 1.42A 5numA-1tqyA:
undetectable		 5numA-1tqyA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1txk GLUCANS BIOSYNTHESIS
PROTEIN G

(Escherichia
coli) 		PF04349
(MdoG) 		4 ILE A 205
LEU A 203
ILE A 193
ILE A  95
 None
 0.73A 5numA-1txkA:
undetectable		 5numA-1txkA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u3b AMYLOID BETA A4
PRECURSOR
PROTEIN-BINDING,
FAMILY A, MEMBER 1

(Homo sapiens) 		PF00595
(PDZ) 		5 VAL A  21
LEU A  64
ILE A  49
ILE A  35
SER A  77
 None
 1.40A 5numA-1u3bA:
undetectable		 5numA-1u3bA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1usv HEAT SHOCK PROTEIN
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90) 		5 ILE A 396
LEU A 400
ILE A 358
ASN A 340
SER A 297
 None
 1.41A 5numA-1usvA:
undetectable		 5numA-1usvA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbl PECTATE LYASE 47

(Bacillus sp.
TS-47) 		PF00544
(Pec_lyase_C) 		5 VAL A 128
ILE A  67
LEU A  69
ILE A 145
ILE A 163
 None
 0.96A 5numA-1vblA:
undetectable		 5numA-1vblA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vma CELL DIVISION
PROTEIN FTSY

(Thermotoga
maritima) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		4 VAL A  48
ILE A  78
LEU A 257
ILE A  75
 None
 0.71A 5numA-1vmaA:
undetectable		 5numA-1vmaA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vyn ARGONAUTE2

(Drosophila
melanogaster) 		PF02170
(PAZ) 		5 ILE A   8
LEU A  11
ILE A  20
ASN A  22
SER A  68
 None
 1.42A 5numA-1vynA:
undetectable		 5numA-1vynA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		5 ILE A 419
LEU A 508
ILE A 416
ILE A 367
ASN A 277
 None
 1.39A 5numA-1w27A:
undetectable		 5numA-1w27A:
7.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w5e FTSZ

(Methanocaldococcus
jannaschii) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		5 VAL A 307
ILE A 337
LEU A 311
ILE A 279
ASN A 271
 None
 1.42A 5numA-1w5eA:
undetectable		 5numA-1w5eA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w9c CRM1 PROTEIN

(Homo sapiens) 		PF08767
(CRM1_C) 		4 VAL A 777
LEU A 781
ILE A 822
ILE A 819
 None
 0.72A 5numA-1w9cA:
undetectable		 5numA-1w9cA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wba WINGED BEAN ALBUMIN
1

(Psophocarpus
tetragonolobus) 		PF00197
(Kunitz_legume) 		5 VAL A   5
ILE A  59
LEU A  13
ILE A  21
SER A 124
 None
 1.37A 5numA-1wbaA:
undetectable		 5numA-1wbaA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmb IAA-AMINO ACID
HYDROLASE HOMOLOG 2

(Arabidopsis
thaliana) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		5 VAL A 270
ILE A 309
LEU A 252
ILE A 248
ILE A 225
 None
 1.31A 5numA-1xmbA:
undetectable		 5numA-1xmbA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1e STILBENE SYNTHASE

(Arachis
hypogaea) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		4 ILE A 128
ILE A 188
ILE A 224
SER A 241
 None
 0.69A 5numA-1z1eA:
undetectable		 5numA-1z1eA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6r MLC PROTEIN

(Escherichia
coli) 		PF00480
(ROK) 		4 ILE A  97
LEU A 116
ILE A  92
ILE A 151
 None
 0.70A 5numA-1z6rA:
undetectable		 5numA-1z6rA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbh 3'-5' EXONUCLEASE
ERI1

(Homo sapiens) 		PF00929
(RNase_T)
PF02037
(SAP) 		5 ILE A 132
ILE A 302
ILE A 260
ASN A 259
SER A 236
 None
 1.28A 5numA-1zbhA:
undetectable		 5numA-1zbhA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbm HYPOTHETICAL PROTEIN
AF1704

(Archaeoglobus
fulgidus) 		PF02621
(VitK2_biosynth) 		4 ILE A  31
LEU A  29
ILE A   3
SER A  71
 None
 0.71A 5numA-1zbmA:
undetectable		 5numA-1zbmA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zbu 3'-5' EXONUCLEASE
ERI1

(Homo sapiens) 		PF00929
(RNase_T) 		5 ILE A 132
ILE A 302
ILE A 260
ASN A 259
SER A 236
 None
 1.32A 5numA-1zbuA:
undetectable		 5numA-1zbuA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0s 6-PYRUVOYL
TETRAHYDROPTERIN
SYNTHASE

(Plasmodium
vivax) 		PF01242
(PTPS) 		4 ILE A  90
LEU A  85
ILE A 127
ILE A 129
 None
 0.69A 5numA-2a0sA:
undetectable		 5numA-2a0sA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a9f PUTATIVE MALIC
ENZYME
((S)-MALATE:NAD+
OXIDOREDUCTASE
(DECARBOXYLATING))

(Streptococcus
pyogenes) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ILE A 110
LEU A 112
ILE A  71
ILE A 134
 None
 0.65A 5numA-2a9fA:
undetectable		 5numA-2a9fA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2an1 PUTATIVE KINASE

(Salmonella
enterica) 		PF01513
(NAD_kinase) 		5 VAL A 164
ILE A 260
LEU A 231
ILE A 181
ILE A 206
 VAL  A 164 ( 0.6A)
ILE  A 260 ( 0.5A)
LEU  A 231 ( 0.5A)
ILE  A 181 ( 0.6A)
ILE  A 206 ( 0.7A)
 1.23A 5numA-2an1A:
undetectable		 5numA-2an1A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4w HYPOTHETICAL
PROTEIN, CONSERVED

(Leishmania
major) 		PF08950
(DUF1861) 		5 ILE A 183
LEU A 184
ILE A 159
ASN A 193
SER A 281
 None
 1.44A 5numA-2b4wA:
undetectable		 5numA-2b4wA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2be9 ASPARTATE
CARBAMOYLTRANSFERASE
REGULATORY CHAIN

(Sulfolobus
acidocaldarius) 		PF01948
(PyrI)
PF02748
(PyrI_C) 		5 VAL B 107
ILE B 154
LEU B 111
ILE B 158
ILE B  81
 None
 1.06A 5numA-2be9B:
undetectable		 5numA-2be9B:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bre ATP-DEPENDENT
MOLECULAR CHAPERONE
HSP82

(Saccharomyces
cerevisiae) 		PF00183
(HSP90)
PF02518
(HATPase_c) 		4 VAL A 201
ILE A 194
ILE A  66
SER A  80
 None
 0.66A 5numA-2breA:
undetectable		 5numA-2breA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c81 GLUTAMINE-2-DEOXY-SC
YLLO-INOSOSE
AMINOTRANSFERASE

(Bacillus
circulans) 		PF01041
(DegT_DnrJ_EryC1) 		5 ILE A 161
LEU A  77
ILE A 183
ILE A 202
SER A 246
 None
 1.36A 5numA-2c81A:
undetectable		 5numA-2c81A:
9.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c9k PESTICIDAL CRYSTAL
PROTEIN CRY4AA

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		5 ILE A 275
LEU A 274
ILE A 125
ILE A 124
SER A 209
 None
 1.50A 5numA-2c9kA:
undetectable		 5numA-2c9kA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvh DNA REPAIR AND
RECOMBINATION
PROTEIN RADB

(Thermococcus
kodakarensis) 		PF08423
(Rad51) 		5 VAL A  48
LEU A 108
ILE A 150
ILE A 152
SER A  58
 None
 1.30A 5numA-2cvhA:
undetectable		 5numA-2cvhA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cya TYROSYL-TRNA
SYNTHETASE

(Aeropyrum
pernix) 		PF00579
(tRNA-synt_1b) 		5 VAL A  67
ILE A  13
LEU A  62
ILE A 209
ILE A  20
 None
 1.50A 5numA-2cyaA:
undetectable		 5numA-2cyaA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d0i DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A  88
LEU A  65
ILE A  68
ILE A  78
 None
 0.66A 5numA-2d0iA:
undetectable		 5numA-2d0iA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d62 MULTIPLE
SUGAR-BINDING
TRANSPORT
ATP-BINDING PROTEIN

(Pyrococcus
horikoshii) 		PF00005
(ABC_tran)
PF08402
(TOBE_2) 		5 VAL A  86
ILE A  52
LEU A 165
ILE A 197
ILE A  29
 None
 1.38A 5numA-2d62A:
undetectable		 5numA-2d62A:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ew1 RAS-RELATED PROTEIN
RAB-30

(Homo sapiens) 		PF00071
(Ras) 		4 ILE A  61
LEU A  59
ILE A  11
ILE A  85
 None
 0.70A 5numA-2ew1A:
undetectable		 5numA-2ew1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2b AQUAPORIN AQPM

(Methanothermobacter
marburgensis) 		PF00230
(MIP) 		4 ILE A 161
LEU A 157
ILE A 179
ILE A  70
 None
GOL  A 501 (-4.8A)
GOL  A 501 ( 4.9A)
None
 0.72A 5numA-2f2bA:
undetectable		 5numA-2f2bA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ft3 BIGLYCAN

(Bos taurus) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		5 ILE A 187
LEU A 213
ILE A 208
ILE A 229
ASN A 251
 None
 1.26A 5numA-2ft3A:
undetectable		 5numA-2ft3A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ft3 BIGLYCAN

(Bos taurus) 		PF01462
(LRRNT)
PF13855
(LRR_8) 		5 LEU A 213
ILE A 208
ILE A 229
ASN A 227
SER A 180
 None
 1.20A 5numA-2ft3A:
undetectable		 5numA-2ft3A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fy2 CHOLINE
O-ACETYLTRANSFERASE

(Homo sapiens) 		PF00755
(Carn_acyltransf) 		5 VAL A 593
ILE A 571
LEU A 597
ILE A 417
SER A 576
 None
 1.33A 5numA-2fy2A:
undetectable		 5numA-2fy2A:
8.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gk1 BETA-HEXOSAMINIDASE
SUBUNIT BETA CHAIN A

(Homo sapiens) 		no annotation 4 ILE N 349
LEU N 351
ILE N 395
ILE N 398
 None
 0.71A 5numA-2gk1N:
undetectable		 5numA-2gk1N:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv8 MONOOXYGENASE

(Schizosaccharomyces
pombe) 		PF00743
(FMO-like)
PF13450
(NAD_binding_8) 		5 VAL A 257
ILE A 260
LEU A 272
ILE A 270
ILE A 281
 None
 1.38A 5numA-2gv8A:
undetectable		 5numA-2gv8A:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hh9 THIAMIN
PYROPHOSPHOKINASE

(Candida
albicans) 		PF04263
(TPK_catalytic)
PF04265
(TPK_B1_binding) 		5 VAL A 312
ILE A  34
LEU A 238
ILE A 322
SER A 305
 None
 1.38A 5numA-2hh9A:
undetectable		 5numA-2hh9A:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hiv THERMOSTABLE DNA
LIGASE

(Sulfolobus
solfataricus) 		PF01068
(DNA_ligase_A_M)
PF04675
(DNA_ligase_A_N)
PF04679
(DNA_ligase_A_C) 		5 VAL A 382
ILE A 307
LEU A 349
ILE A 268
ILE A 275
 None
 1.18A 5numA-2hivA:
undetectable		 5numA-2hivA:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ia7 TAIL LYSOZYME,
PUTATIVE

(Geobacter
sulfurreducens) 		PF04965
(GPW_gp25) 		5 VAL A  78
ILE A  40
LEU A  41
ILE A  37
ILE A  89
 None
 1.09A 5numA-2ia7A:
undetectable		 5numA-2ia7A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ib5 CHROMO PROTEIN

(Epiactis
japonica) 		PF01353
(GFP) 		4 LEU A  13
ILE A 119
ILE A 121
SER A  54
 None
 0.66A 5numA-2ib5A:
undetectable		 5numA-2ib5A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inv INSULIN
FRUCTOTRANSFERASE

(Bacillus sp.
snu-7) 		no annotation 4 VAL A 113
ILE A 122
ILE A 100
SER A  72
 None
 0.67A 5numA-2invA:
undetectable		 5numA-2invA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inv INSULIN
FRUCTOTRANSFERASE

(Bacillus sp.
snu-7) 		no annotation 4 VAL A 113
ILE A 122
ILE A 102
SER A  72
 None
 0.64A 5numA-2invA:
undetectable		 5numA-2invA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j66 BTRK

(Bacillus
circulans) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 ILE A 245
LEU A 240
ILE A 198
SER A  47
 None
None
EDO  A1418 (-3.9A)
PLP  A1419 (-3.2A)
 0.70A 5numA-2j66A:
undetectable		 5numA-2j66A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jaq DEOXYGUANOSINE
KINASE

(Mycoplasma
mycoides) 		PF01712
(dNK) 		6 VAL A 181
ILE A   5
LEU A 131
ILE A  16
ILE A  20
SER A 200
 None
 1.39A 5numA-2jaqA:
undetectable		 5numA-2jaqA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jem ENDO-BETA-1,4-GLUCAN
ASE

(Bacillus
licheniformis) 		PF01670
(Glyco_hydro_12) 		5 VAL A 258
ILE A 138
ILE A 215
ILE A 158
SER A 123
 None
 1.38A 5numA-2jemA:
undetectable		 5numA-2jemA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jua DE NOVO PROTEIN S836

(unidentified) 		no annotation 5 ILE A  44
LEU A  12
ILE A  41
ASN A  39
MET A  60
 None
 1.41A 5numA-2juaA:
undetectable		 5numA-2juaA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kyb MANNOSYL-GLYCOPROTEI
N
ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE DOMAIN
PROTEIN, POSSIBLE
ENTEROTOXIN

(Clostridium
perfringens) 		PF08239
(SH3_3) 		5 VAL A  14
ILE A  46
ILE A  60
ASN A   7
SER A  10
 None
 0.97A 5numA-2kybA:
undetectable		 5numA-2kybA:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ltm NFU1 IRON-SULFUR
CLUSTER SCAFFOLD
HOMOLOG,
MITOCHONDRIAL

(Homo sapiens) 		PF08712
(Nfu_N) 		5 VAL A  64
ILE A  89
LEU A  55
ILE A  93
ILE A  13
 None
 1.21A 5numA-2ltmA:
undetectable		 5numA-2ltmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mx2 DEUBIQUITINATING
PROTEIN VCIP135

(Rattus
norvegicus) 		no annotation 4 VAL A  71
ILE A  79
ILE A  50
ILE A  37
 None
 0.70A 5numA-2mx2A:
undetectable		 5numA-2mx2A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nml ENHANCER OF
RUDIMENTARY HOMOLOG

(Homo sapiens) 		PF01133
(ER) 		5 VAL A   8
ILE A  61
LEU A  67
ILE A  87
ILE A  91
 None
 1.38A 5numA-2nmlA:
undetectable		 5numA-2nmlA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nml ENHANCER OF
RUDIMENTARY HOMOLOG

(Homo sapiens) 		PF01133
(ER) 		5 VAL A   8
ILE A  61
LEU A  67
ILE A  87
MET A  35
 None
 1.24A 5numA-2nmlA:
undetectable		 5numA-2nmlA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nra PI PROTEIN

(Escherichia
coli) 		PF01051
(Rep_3) 		5 ILE C 121
LEU C  84
ILE C 120
ILE C 141
SER C  45
 None
 1.12A 5numA-2nraC:
undetectable		 5numA-2nraC:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7q BIFUNCTIONAL
3-DEHYDROQUINATE
DEHYDRATASE/SHIKIMAT
E DEHYDROGENASE

(Arabidopsis
thaliana) 		PF01487
(DHquinase_I)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 VAL A 457
LEU A 517
ILE A 534
ASN A 508
 None
 0.71A 5numA-2o7qA:
undetectable		 5numA-2o7qA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o9a ACETATE OPERON
REPRESSOR

(Escherichia
coli) 		PF01614
(IclR) 		5 VAL A  26
ILE A  14
LEU A  15
ILE A 133
SER A 116
 None
 1.14A 5numA-2o9aA:
undetectable		 5numA-2o9aA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okj GLUTAMATE
DECARBOXYLASE 1

(Homo sapiens) 		PF00282
(Pyridoxal_deC) 		5 VAL A 513
ILE A 494
LEU A 490
ILE A 584
ILE A 587
 None
 1.45A 5numA-2okjA:
undetectable		 5numA-2okjA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pd2 HYPOTHETICAL PROTEIN
ST0148

(Sulfurisphaera
tokodaii) 		PF02635
(DrsE) 		5 VAL A  13
LEU A  17
ILE A  54
ILE A  85
SER A  70
 None
 1.45A 5numA-2pd2A:
undetectable		 5numA-2pd2A:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pef SERINE PROTEASE
INHIBITOR

(Caldanaerobacter
subterraneus) 		PF00079
(Serpin) 		5 ILE A  68
LEU A 292
ILE A 298
ASN A 411
SER A 273
 None
 1.17A 5numA-2pefA:
undetectable		 5numA-2pefA:
12.02