SIMILAR PATTERNS OF AMINO ACIDS FOR 5NUJ_A_Z80A201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0u HISTIDINE PERMEASE

(Salmonella
enterica) 		PF00005
(ABC_tran) 		4 VAL A 207
LEU A 176
ILE A  63
VAL A  65
 None
 0.65A 5nujA-1b0uA:
0.0		 5nujA-1b0uA:
14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dof ADENYLOSUCCINATE
LYASE

(Pyrobaculum
aerophilum) 		PF00206
(Lyase_1) 		4 ALA A 119
VAL A 122
LEU A 331
ILE A 277
 None
 0.73A 5nujA-1dofA:
undetectable		 5nujA-1dofA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1js8 HEMOCYANIN

(Enteroctopus
dofleini) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		5 ALA A2808
PHE A2799
LEU A2801
ASN A2811
VAL A2867
 None
 1.43A 5nujA-1js8A:
0.0		 5nujA-1js8A:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lbq FERROCHELATASE

(Saccharomyces
cerevisiae) 		PF00762
(Ferrochelatase) 		4 ALA A 112
VAL A 115
ILE A 196
VAL A 158
 None
 0.67A 5nujA-1lbqA:
0.0		 5nujA-1lbqA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lsh LIPOVITELLIN (LV-1N,
LV-1C)

(Ichthyomyzon
unicuspis) 		PF01347
(Vitellogenin_N)
PF09172
(DUF1943) 		4 ALA A 115
VAL A 101
LEU A  64
ASN A 125
 None
 0.80A 5nujA-1lshA:
1.7		 5nujA-1lshA:
6.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m93 SERINE PROTEINASE
INHIBITOR 2

(Cowpox virus) 		PF00079
(Serpin) 		4 PHE B 219
LEU B 214
ILE B 185
VAL B 197
 None
 0.83A 5nujA-1m93B:
0.6		 5nujA-1m93B:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mo2 ERYTHRONOLIDE
SYNTHASE, MODULES 5
AND 6

(Saccharopolyspora
erythraea) 		PF00975
(Thioesterase) 		5 ALA A 100
VAL A  98
LEU A  92
ILE A 168
VAL A 166
 None
 1.19A 5nujA-1mo2A:
0.0		 5nujA-1mo2A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r6b CLPA PROTEIN

(Escherichia
coli) 		PF00004
(AAA)
PF02861
(Clp_N)
PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 VAL X 733
LEU X 742
ILE X 708
VAL X 662
 None
 0.75A 5nujA-1r6bX:
0.0		 5nujA-1r6bX:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1squ CHEX PROTEIN

(Thermotoga
maritima) 		PF13690
(CheX) 		4 ALA A  65
VAL A  68
LEU A  21
ILE A 137
 None
 0.84A 5nujA-1squA:
0.0		 5nujA-1squA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE

(Sulfurisphaera
tokodaii) 		PF01035
(DNA_binding_1) 		4 ALA A  95
VAL A 105
LEU A 109
ILE A  83
 None
 0.82A 5nujA-1wrjA:
undetectable		 5nujA-1wrjA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfb ALDOLASE C

(Homo sapiens) 		PF00274
(Glycolytic) 		4 ALA A 321
VAL A  62
ILE A  47
VAL A  49
 None
 0.83A 5nujA-1xfbA:
undetectable		 5nujA-1xfbA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yc6 COAT PROTEIN

(Brome mosaic
virus) 		no annotation 4 ALA A 144
VAL A  87
ILE A  71
VAL A 108
 None
 0.77A 5nujA-1yc6A:
undetectable		 5nujA-1yc6A:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ynb HYPOTHETICAL PROTEIN
AF1432

(Archaeoglobus
fulgidus) 		PF13023
(HD_3) 		4 ALA A 146
VAL A 149
LEU A 151
ILE A  49
 None
 0.85A 5nujA-1ynbA:
undetectable		 5nujA-1ynbA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqq XANTHOSINE
PHOSPHORYLASE

(Escherichia
coli) 		PF01048
(PNP_UDP_1) 		4 ALA A  29
VAL A  80
LEU A  71
ILE A  14
 None
 0.83A 5nujA-1yqqA:
undetectable		 5nujA-1yqqA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6r MLC PROTEIN

(Escherichia
coli) 		PF00480
(ROK) 		4 ALA A  18
VAL A  21
LEU A  36
MET A  54
 None
 0.80A 5nujA-1z6rA:
undetectable		 5nujA-1z6rA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b42 XYLANASE INHIBITOR-I

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 VAL A 346
PHE A 330
LEU A 243
VAL A 300
 None
 0.71A 5nujA-2b42A:
undetectable		 5nujA-2b42A:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bf6 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF13088
(BNR_2) 		4 VAL A 583
PHE A 553
LEU A 561
VAL A 605
 None
 0.75A 5nujA-2bf6A:
undetectable		 5nujA-2bf6A:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2daf FLJ35834 PROTEIN

(Homo sapiens) 		PF00240
(ubiquitin) 		4 VAL A  97
PHE A  46
LEU A  50
VAL A  20
 None
 0.74A 5nujA-2dafA:
undetectable		 5nujA-2dafA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dn5 GENERAL
TRANSCRIPTION FACTOR
II-I REPEAT
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF02946
(GTF2I) 		4 VAL A  76
PHE A  55
LEU A  49
VAL A  32
 None
 0.80A 5nujA-2dn5A:
undetectable		 5nujA-2dn5A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g9i F420-0:GAMMA-GLUTAMY
L LIGASE

(Archaeoglobus
fulgidus) 		PF01996
(F420_ligase) 		4 ALA A 129
VAL A 146
LEU A  36
VAL A  42
 None
 0.84A 5nujA-2g9iA:
undetectable		 5nujA-2g9iA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gkp HYPOTHETICAL PROTEIN
NMB0488

(Neisseria
meningitidis) 		PF07262
(CdiI) 		4 ALA A  58
LEU A  51
ILE A 122
VAL A 111
 None
None
None
EDO  A 402 ( 4.7A)
 0.84A 5nujA-2gkpA:
undetectable		 5nujA-2gkpA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hjr MALATE DEHYDROGENASE

(Cryptosporidium
parvum) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 VAL A 299
PHE A 309
LEU A 301
VAL A 282
 None
 0.76A 5nujA-2hjrA:
undetectable		 5nujA-2hjrA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iwn MULTIPLE PDZ DOMAIN
PROTEIN

(Homo sapiens) 		PF00595
(PDZ) 		4 VAL A 378
LEU A 380
ILE A 410
VAL A 407
 None
 0.84A 5nujA-2iwnA:
undetectable		 5nujA-2iwnA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jan TYROSYL-TRNA
SYNTHETASE

(Mycobacterium
tuberculosis) 		PF00579
(tRNA-synt_1b) 		4 ALA A 261
PHE A 272
LEU A 300
VAL A 224
 None
 0.52A 5nujA-2janA:
undetectable		 5nujA-2janA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ju1 ERYTHRONOLIDE
SYNTHASE

(Saccharopolyspora
erythraea) 		PF00550
(PP-binding) 		4 ALA A  83
VAL A  86
LEU A  76
VAL A  32
 None
 0.75A 5nujA-2ju1A:
undetectable		 5nujA-2ju1A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kso EPHRIN TYPE-A
RECEPTOR 2

(Homo sapiens) 		PF00536
(SAM_1) 		4 ALA A  38
VAL A  15
LEU A  19
ILE A  53
 None
 0.84A 5nujA-2ksoA:
undetectable		 5nujA-2ksoA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l4r POTASSIUM
VOLTAGE-GATED
CHANNEL SUBFAMILY H
MEMBER 2

(Homo sapiens) 		PF13426
(PAS_9) 		4 ALA A  32
VAL A  41
ASN A 128
VAL A 110
 None
 0.86A 5nujA-2l4rA:
undetectable		 5nujA-2l4rA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og9 MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Polaromonas sp.
JS666) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 VAL A 212
PHE A 233
LEU A 235
ILE A 229
 None
 0.78A 5nujA-2og9A:
undetectable		 5nujA-2og9A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pxg OUTER MEMBRANE
PROTEIN

(Xanthomonas
citri) 		PF04355
(SmpA_OmlA) 		4 ALA A  37
PHE A  72
ILE A  18
VAL A  23
 None
 0.76A 5nujA-2pxgA:
undetectable		 5nujA-2pxgA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v6c PROLIFERATION-ASSOCI
ATED PROTEIN 2G4

(Mus musculus) 		PF00557
(Peptidase_M24) 		4 VAL A 323
PHE A 218
LEU A 325
VAL A 166
 None
 0.79A 5nujA-2v6cA:
undetectable		 5nujA-2v6cA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wed PENICILLOPEPSIN

(Penicillium
janthinellum) 		PF00026
(Asp) 		4 ALA A 200
PHE A 298
LEU A 219
VAL A 195
 None
 0.84A 5nujA-2wedA:
undetectable		 5nujA-2wedA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT

(Rhodobacter
capsulatus) 		PF13519
(VWA_2) 		4 VAL A 136
PHE A  13
LEU A 111
MET A 182
 None
 0.79A 5nujA-2x31A:
undetectable		 5nujA-2x31A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yn3 PUTATIVE INNER
MEMBRANE PROTEIN

(Salmonella
enterica) 		PF12245
(Big_3_2) 		4 ALA A5103
VAL A5121
LEU A5107
ASN A5081
 None
None
None
IOD  A6361 ( 4.9A)
 0.82A 5nujA-2yn3A:
undetectable		 5nujA-2yn3A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywv PHOSPHORIBOSYLAMINOI
MIDAZOLE
SUCCINOCARBOXAMIDE
SYNTHETASE

(Geobacillus
kaustophilus) 		PF01259
(SAICAR_synt) 		4 ALA A 156
VAL A 159
PHE A  59
LEU A  62
 None
 0.84A 5nujA-2ywvA:
undetectable		 5nujA-2ywvA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z15 PROTEIN TOB1

(Homo sapiens) 		PF07742
(BTG) 		4 VAL A  76
LEU A  41
ILE A 103
VAL A 101
 None
 0.73A 5nujA-2z15A:
undetectable		 5nujA-2z15A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aq1 THERMOSOME SUBUNIT

(Methanococcoides
burtonii) 		PF00118
(Cpn60_TCP1) 		4 PHE B 281
LEU B 230
ASN B 278
VAL B 339
 None
 0.82A 5nujA-3aq1B:
undetectable		 5nujA-3aq1B:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3av6 DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Mus musculus) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC)
PF12047
(DNMT1-RFD) 		4 ALA A 603
PHE A 485
ILE A 433
VAL A 428
 None
 0.82A 5nujA-3av6A:
undetectable		 5nujA-3av6A:
4.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Plasmodium
vivax) 		PF02542
(YgbB) 		4 ALA A  71
LEU A 105
ILE A 119
VAL A 155
 None
 0.84A 5nujA-3b6nA:
undetectable		 5nujA-3b6nA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b6n 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Plasmodium
vivax) 		PF02542
(YgbB) 		4 ALA A  75
LEU A 105
ILE A 150
VAL A 155
 None
 0.51A 5nujA-3b6nA:
undetectable		 5nujA-3b6nA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483

(Discosoma
striata) 		PF01353
(GFP) 		4 VAL A  44
LEU A  46
ILE A 122
ASN A 109
 CRQ  A  66 ( 4.3A)
None
None
CRQ  A  66 ( 4.1A)
 0.82A 5nujA-3cglA:
undetectable		 5nujA-3cglA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dlo UNIVERSAL STRESS
PROTEIN

(Archaeoglobus
fulgidus) 		PF00582
(Usp) 		4 ALA A  17
VAL A  20
ILE A  88
VAL A  38
 None
 0.80A 5nujA-3dloA:
undetectable		 5nujA-3dloA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e77 PHOSPHOSERINE
AMINOTRANSFERASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		4 ALA A 198
VAL A 202
LEU A 182
ILE A 211
 None
 0.78A 5nujA-3e77A:
undetectable		 5nujA-3e77A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e77 PHOSPHOSERINE
AMINOTRANSFERASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		4 ALA A 198
VAL A 202
LEU A 182
VAL A  72
 None
 0.83A 5nujA-3e77A:
undetectable		 5nujA-3e77A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eto NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1

(Homo sapiens) 		PF00066
(Notch)
PF06816
(NOD)
PF07684
(NODP) 		4 VAL A1605
LEU A1601
ILE A1719
VAL A1722
 None
 0.81A 5nujA-3etoA:
undetectable		 5nujA-3etoA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flo DNA POLYMERASE ALPHA
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF04042
(DNA_pol_E_B)
PF08418
(Pol_alpha_B_N) 		4 ALA A 641
PHE A 531
ILE A 430
VAL A 395
 None
 0.82A 5nujA-3floA:
undetectable		 5nujA-3floA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h8f CYTOSOL
AMINOPEPTIDASE

(Pseudomonas
putida) 		PF00883
(Peptidase_M17)
PF02789
(Peptidase_M17_N) 		4 ALA A 108
VAL A 157
LEU A   3
VAL A  93
 None
 0.86A 5nujA-3h8fA:
undetectable		 5nujA-3h8fA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hd8 XYLANASE INHIBITOR

(Triticum
aestivum) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		4 VAL A 348
PHE A 332
LEU A 245
VAL A 302
 None
 0.83A 5nujA-3hd8A:
undetectable		 5nujA-3hd8A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwj E3 UBIQUITIN-PROTEIN
LIGASE MYCBP2

(Mus musculus) 		PF08005
(PHR) 		4 VAL A1796
PHE A1758
LEU A1771
VAL A1755
 None
 0.81A 5nujA-3hwjA:
undetectable		 5nujA-3hwjA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3id1 REGULATOR OF SIGMA E
PROTEASE

(Escherichia
coli) 		no annotation 4 VAL A 193
LEU A 195
ILE A 134
VAL A 131
 None
 0.82A 5nujA-3id1A:
undetectable		 5nujA-3id1A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ifq PLAKOGLOBIN

(Homo sapiens) 		PF00514
(Arm) 		4 VAL A 607
LEU A 611
ILE A 524
VAL A 528
 None
 0.86A 5nujA-3ifqA:
undetectable		 5nujA-3ifqA:
9.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j2i PROLIFERATION-ASSOCI
ATED PROTEIN 2G4

(Homo sapiens) 		PF00557
(Peptidase_M24) 		4 VAL A 323
PHE A 218
LEU A 325
VAL A 166
 None
 0.83A 5nujA-3j2iA:
undetectable		 5nujA-3j2iA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd8 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Thermoplasma
acidophilum) 		PF01676
(Metalloenzyme)
PF10143
(PhosphMutase) 		4 PHE A 135
LEU A 147
ASN A 188
VAL A 186
 None
 0.86A 5nujA-3kd8A:
undetectable		 5nujA-3kd8A:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3khk TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLATION SUBUNIT

(Methanosarcina
mazei) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		4 VAL A 423
LEU A 425
ILE A 483
MET A 239
 None
 0.75A 5nujA-3khkA:
undetectable		 5nujA-3khkA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx2 PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43

(Saccharomyces
cerevisiae) 		no annotation 4 ALA B 157
VAL B 160
ILE B 213
VAL B 143
 None
 0.49A 5nujA-3kx2B:
undetectable		 5nujA-3kx2B:
8.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kza BETA-LACTOGLOBULIN

(Bos taurus;
Equus caballus) 		PF00061
(Lipocalin) 		4 VAL A  41
LEU A  58
VAL A  92
MET A 107
 None
 0.66A 5nujA-3kzaA:
24.5		 5nujA-3kzaA:
75.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lvv GLUTAMATE--CYSTEINE
LIGASE

(Saccharomyces
cerevisiae) 		PF03074
(GCS) 		4 ALA A 407
LEU A 367
ILE A 415
ASN A 387
 None
 0.85A 5nujA-3lvvA:
undetectable		 5nujA-3lvvA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n2q SEX PHEROMONE
STAPH-CAM373

(Bacillus cereus) 		PF07537
(CamS) 		4 VAL A 312
LEU A 306
ILE A 252
VAL A 263
 None
 0.82A 5nujA-3n2qA:
undetectable		 5nujA-3n2qA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ogg BOTULINUM NEUROTOXIN
TYPE D

(Clostridium
botulinum) 		PF07951
(Toxin_R_bind_C)
PF07953
(Toxin_R_bind_N) 		4 VAL A 916
LEU A 918
ASN A1061
VAL A 933
 None
 0.81A 5nujA-3oggA:
undetectable		 5nujA-3oggA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pl5 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Streptococcus
mutans) 		PF02645
(DegV) 		4 VAL A 259
LEU A 261
ASN A  21
MET A 133
 None
 0.84A 5nujA-3pl5A:
undetectable		 5nujA-3pl5A:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tev GLYCOSYL HYROLASE,
FAMILY 3

(Deinococcus
radiodurans) 		PF00933
(Glyco_hydro_3) 		4 ALA A  43
LEU A  23
VAL A  67
MET A  68
 None
 0.78A 5nujA-3tevA:
undetectable		 5nujA-3tevA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4blu RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J

(Escherichia
coli) 		PF04378
(RsmJ) 		4 ALA A  80
LEU A  74
ILE A  65
VAL A  16
 None
 0.85A 5nujA-4bluA:
undetectable		 5nujA-4bluA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g6u EC869 CDII

(Escherichia
coli) 		PF07262
(CdiI) 		4 ALA B  58
LEU B  51
ILE B 121
VAL B 110
 None
 0.83A 5nujA-4g6uB:
undetectable		 5nujA-4g6uB:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q5t LIPOPROTEIN

(Streptococcus
mutans) 		PF03180
(Lipoprotein_9) 		4 VAL A  34
LEU A  32
ILE A 256
VAL A 106
 None
 0.81A 5nujA-4q5tA:
undetectable		 5nujA-4q5tA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qk3 CARBONIC ANHYDRASE 2

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		4 ALA A 153
PHE A  95
LEU A 148
VAL A 160
 None
 0.78A 5nujA-4qk3A:
undetectable		 5nujA-4qk3A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9x COPPER HOMEOSTASIS
PROTEIN CUTC

(Bacillus
anthracis) 		PF03932
(CutC) 		4 ALA A  44
VAL A  48
ILE A 212
VAL A   4
 None
 0.86A 5nujA-4r9xA:
undetectable		 5nujA-4r9xA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rcw SLIT AND NTRK-LIKE
PROTEIN 1

(Homo sapiens) 		PF13855
(LRR_8) 		4 PHE A 419
LEU A 446
ASN A 416
VAL A 414
 None
 0.82A 5nujA-4rcwA:
undetectable		 5nujA-4rcwA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rev DISEASE RESISTANCE
RESPONSE PROTEIN 206

(Pisum sativum) 		PF03018
(Dirigent) 		4 PHE A 117
LEU A 119
ILE A 178
VAL A 176
 None
 0.81A 5nujA-4revA:
2.3		 5nujA-4revA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry9 PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Verminephrobacter
eiseniae) 		PF13407
(Peripla_BP_4) 		4 ALA A  51
ILE A 122
ASN A  98
VAL A  40
 None
None
TLZ  A 401 ( 4.4A)
None
 0.81A 5nujA-4ry9A:
undetectable		 5nujA-4ry9A:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twl DIOSCORIN 5

(Dioscorea
japonica) 		PF00194
(Carb_anhydrase) 		4 ALA A 136
PHE A  96
LEU A 111
ILE A 147
 None
 0.69A 5nujA-4twlA:
1.1		 5nujA-4twlA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4twl DIOSCORIN 5

(Dioscorea
japonica) 		PF00194
(Carb_anhydrase) 		4 VAL A 202
PHE A  96
LEU A 111
ILE A 147
 None
 0.86A 5nujA-4twlA:
1.1		 5nujA-4twlA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zmu DIGUANYLATE CYCLASE

(Pseudomonas
aeruginosa) 		PF00990
(GGDEF)
PF01590
(GAF) 		4 ALA A 248
PHE A 264
LEU A 256
ILE A 303
 None
 0.72A 5nujA-4zmuA:
undetectable		 5nujA-4zmuA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c1b TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE

(Homo sapiens) 		PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2)
PF09336
(Vps4_C) 		4 VAL A 367
LEU A 243
VAL A 220
MET A 219
 None
 0.78A 5nujA-5c1bA:
undetectable		 5nujA-5c1bA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ci9 PROTEIN TOB1

(Homo sapiens) 		PF07742
(BTG) 		4 VAL A  67
LEU A  32
ILE A  94
VAL A  92
 None
 0.79A 5nujA-5ci9A:
undetectable		 5nujA-5ci9A:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5do7 ATP-BINDING CASSETTE
SUB-FAMILY G MEMBER
5

(Homo sapiens) 		PF00005
(ABC_tran)
PF01061
(ABC2_membrane) 		4 VAL A 246
PHE A 129
LEU A 215
VAL A 113
 None
 0.77A 5nujA-5do7A:
undetectable		 5nujA-5do7A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dzs SHIKIMATE
DEHYDROGENASE
(NADP(+))

(Clostridioides
difficile) 		PF08501
(Shikimate_dh_N) 		4 ALA A  84
LEU A  72
ILE A  43
VAL A   7
 None
 0.72A 5nujA-5dzsA:
undetectable		 5nujA-5dzsA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fof LEUCYL-TRNA
SYNTHETASE

(Plasmodium
knowlesi) 		no annotation 4 PHE A 283
LEU A 419
ILE A 411
VAL A 342
 None
 0.84A 5nujA-5fofA:
undetectable		 5nujA-5fofA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h5c MITOCHONDRIAL
DISTRIBUTION AND
MORPHOLOGY PROTEIN
12

(Kluyveromyces
lactis) 		no annotation 4 VAL A  92
LEU A  90
ILE A   5
VAL A   3
 None
 0.83A 5nujA-5h5cA:
2.0		 5nujA-5h5cA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ha5 BRUCELLA OVIS
OXIDOREDUCTASE

(Brucella ovis) 		PF13561
(adh_short_C2) 		4 ALA A  80
LEU A 134
ILE A  42
VAL A  44
 None
 0.84A 5nujA-5ha5A:
undetectable		 5nujA-5ha5A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hcc COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01821
(ANATO)
PF07677
(A2M_recep)
PF07678
(A2M_comp) 		4 PHE A1600
LEU A1639
ILE A1565
VAL A1563
 None
 0.48A 5nujA-5hccA:
undetectable		 5nujA-5hccA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i1t STAGE II SPORULATION
PROTEIN D

(Clostridioides
difficile) 		PF08486
(SpoIID) 		4 VAL A 292
PHE A 241
ILE A 254
VAL A 263
 None
 0.84A 5nujA-5i1tA:
undetectable		 5nujA-5i1tA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5irr SEPTIN-LIKE PROTEIN

(Chlamydomonas
reinhardtii) 		PF00735
(Septin) 		4 VAL A 310
PHE A 300
LEU A 305
VAL A 258
 None
 0.80A 5nujA-5irrA:
0.8		 5nujA-5irrA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jou ALPHA-XYLOSIDASE
BOGH31A

(Bacteroides
ovatus) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF17137
(DUF5110) 		4 PHE A 812
LEU A 835
ILE A 843
MET A 741
 None
 0.76A 5nujA-5jouA:
0.4		 5nujA-5jouA:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5llq METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE

(Sulfolobus
solfataricus) 		PF01035
(DNA_binding_1) 		4 ALA A  94
VAL A 104
LEU A 108
ILE A  82
 None
 0.82A 5nujA-5llqA:
undetectable		 5nujA-5llqA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg3 PROTEIN TRANSLOCASE
SUBUNIT SECD

(Escherichia
coli) 		PF02355
(SecD_SecF)
PF07549
(Sec_GG)
PF13721
(SecD-TM1) 		4 PHE D 406
LEU D 345
ILE D 398
ASN D 360
 None
 0.85A 5nujA-5mg3D:
undetectable		 5nujA-5mg3D:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mxp -

(-) 		no annotation 4 ALA A 250
VAL A 253
ILE A 275
VAL A 268
 None
 0.86A 5nujA-5mxpA:
undetectable		 5nujA-5mxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8o DNA HELICASE I

(Escherichia
coli) 		PF07057
(TraI)
PF08751
(TrwC)
PF13604
(AAA_30) 		4 VAL A 208
LEU A 102
VAL A 229
MET A 226
 None
 0.75A 5nujA-5n8oA:
undetectable		 5nujA-5n8oA:
4.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o0s GLUCOSYLCERAMIDASE

(Thermoanaerobacterium
xylanolyticum) 		PF04685
(DUF608)
PF12215
(Glyco_hydr_116N)
PF17168
(DUF5127) 		4 ALA A 610
LEU A 568
ILE A 618
VAL A 542
 None
 0.84A 5nujA-5o0sA:
2.2		 5nujA-5o0sA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2j PROBABLE PHOSPHITE
TRANSPORT
SYSTEM-BINDING
PROTEIN PTXB

(Pseudomonas
stutzeri) 		no annotation 4 PHE A 177
LEU A 172
ILE A 186
VAL A 191
 None
 0.83A 5nujA-5o2jA:
undetectable		 5nujA-5o2jA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oei UNCHARACTERIZED
PROTEIN FAMILY
UPF0065:TAT PATHWAY
SIGNAL

(Rhodopseudomonas
palustris) 		no annotation 4 ALA A 267
LEU A  44
ILE A 132
VAL A 283
 None
 0.81A 5nujA-5oeiA:
undetectable		 5nujA-5oeiA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ux5 BIFUNCTIONAL PROTEIN
PROLINE UTILIZATION
A (PUTA)

(Corynebacterium
freiburgense) 		PF00171
(Aldedh)
PF01619
(Pro_dh) 		4 ALA A 188
VAL A 191
LEU A 169
ILE A 227
 None
 0.69A 5nujA-5ux5A:
undetectable		 5nujA-5ux5A:
5.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyd PHOSPHODIESTERASE

(Salpingoeca
rosetta) 		no annotation 4 ALA A 235
PHE A 307
LEU A 310
VAL A 227
 None
 0.73A 5nujA-5vydA:
undetectable		 5nujA-5vydA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wel CHIMERA OF GLUTAMATE
RECEPTOR 2, GERM
CELL-SPECIFIC GENE
1-LIKE PROTEIN

(Mus musculus;
Rattus
norvegicus) 		PF00060
(Lig_chan)
PF01094
(ANF_receptor)
PF07803
(GSG-1)
PF10613
(Lig_chan-Glu_bd) 		4 ALA A 288
PHE A 258
LEU A 341
VAL A  31
 None
 0.72A 5nujA-5welA:
undetectable		 5nujA-5welA:
5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5weo GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT
CHIMERA

(Mus musculus;
Rattus
norvegicus) 		PF00060
(Lig_chan)
PF00822
(PMP22_Claudin)
PF01094
(ANF_receptor)
PF10613
(Lig_chan-Glu_bd) 		4 ALA A 288
PHE A 258
LEU A 341
VAL A  31
 None
 0.70A 5nujA-5weoA:
undetectable		 5nujA-5weoA:
6.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wfc HISTONE-LYSINE-N-MET
HYLTRANSFERASE EZH2,
POLYCOMB PROTEIN
SUZ12 CHIMERA

(Chaetomium
thermophilum) 		no annotation 4 ALA B 210
VAL B 213
ILE B 462
VAL B 457
 None
 0.72A 5nujA-5wfcB:
undetectable		 5nujA-5wfcB:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wl3 ENGINEERED CHALCONE
ISOMERASE ANCR2

(unidentified) 		no annotation 5 ALA A 129
VAL A 176
PHE A 150
LEU A 158
VAL A 108
 None
 1.26A 5nujA-5wl3A:
1.1		 5nujA-5wl3A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xdr PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE DHX15

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind) 		4 ALA A 202
VAL A 205
ILE A 258
VAL A 188
 None
 0.60A 5nujA-5xdrA:
undetectable		 5nujA-5xdrA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwu LEUCINE-RICH REPEAT
AND FIBRONECTIN TYPE
III
DOMAIN-CONTAINING
PROTEIN 1

(Mus musculus) 		no annotation 4 ALA B 156
PHE B 109
LEU B 136
VAL B 104
 None
 0.62A 5nujA-5xwuB:
undetectable		 5nujA-5xwuB:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aoo MALATE DEHYDROGENASE

(Haemophilus
influenzae) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ALA A 106
LEU A 143
ILE A  75
VAL A  98
 None
 0.85A 5nujA-6aooA:
undetectable		 5nujA-6aooA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bt4 S-LAYER PROTEIN SAP

(Bacillus
anthracis) 		no annotation 4 ALA A 169
LEU A 138
ILE A 129
VAL A 191
 None
 0.83A 5nujA-6bt4A:
undetectable		 5nujA-6bt4A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e2q -

(-) 		no annotation 4 ALA A 286
VAL A 272
LEU A 356
ILE A 290
 None
 0.77A 5nujA-6e2qA:
undetectable		 5nujA-6e2qA:
undetectable