SIMILAR PATTERNS OF AMINO ACIDS FOR 5NOO_C_D16C402_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1am5 | PEPSIN (Gadus morhua) |
PF00026(Asp) | 5 | ASP A 303LEU A 306GLY A 302PHE A 301TYR A 14 | None | 1.22A | 5nooC-1am5A:0.0 | 5nooC-1am5A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bpo | PROTEIN (CLATHRIN) (Rattusnorvegicus) |
PF01394(Clathrin_propel)PF09268(Clathrin-link)PF13838(Clathrin_H_link) | 4 | ASP A 423LEU A 422GLY A 419PHE A 418 | None | 1.05A | 5nooC-1bpoA:undetectable | 5nooC-1bpoA:19.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bs0 | PROTEIN(8-AMINO-7-OXONANOATE SYNTHASE) (Escherichiacoli) |
PF00155(Aminotran_1_2) | 4 | ASP A 48LEU A 52GLY A 239PHE A 238 | None | 1.05A | 5nooC-1bs0A:0.0 | 5nooC-1bs0A:23.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1bsf | THYMIDYLATE SYNTHASEA (Bacillussubtilis) |
PF00303(Thymidylat_synt) | 4 | ASP A 184GLY A 188PHE A 191TYR A 224 | None | 0.39A | 5nooC-1bsfA:30.2 | 5nooC-1bsfA:34.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c0a | ASPARTYL TRNASYNTHETASE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 4 | ASP A 519LEU A 518GLY A 515PHE A 514 | NoneNoneNone A B 676 ( 4.6A) | 1.04A | 5nooC-1c0aA:0.0 | 5nooC-1c0aA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c0a | ASPARTYL TRNASYNTHETASE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 4 | ASP A 536LEU A 535GLY A 534PHE A 533 | NoneNoneAMO A 831 (-3.4A)None | 0.86A | 5nooC-1c0aA:0.0 | 5nooC-1c0aA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c7o | CYSTALYSIN (Treponemadenticola) |
PF00155(Aminotran_1_2) | 4 | TYR A 124ASP A 362GLY A 361PHE A 360 | None | 1.06A | 5nooC-1c7oA:0.0 | 5nooC-1c7oA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ch4 | MODULE-SUBSTITUTEDCHIMERA HEMOGLOBINBETA-ALPHA (Homo sapiens) |
PF00042(Globin) | 4 | ASP A 47LEU A 48GLY A 46PHE A 45 | NoneNoneNoneHEM A 147 (-4.7A) | 0.99A | 5nooC-1ch4A:undetectable | 5nooC-1ch4A:20.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ci7 | PROTEIN (THYMIDYLATESYNTHASE) (Pneumocystiscarinii) |
PF00303(Thymidylat_synt) | 5 | ASP A 202LEU A 205GLY A 206PHE A 209TYR A 242 | CB3 A 768 ( 3.6A)CB3 A 768 ( 4.4A)UMP A 767 (-3.7A)CB3 A 768 (-3.6A)CB3 A 768 ( 4.7A) | 0.75A | 5nooC-1ci7A:12.5 | 5nooC-1ci7A:53.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvy | THYMIDYLATE SYNTHASE (Homo sapiens) |
PF00303(Thymidylat_synt) | 5 | ASP A 218LEU A 221GLY A 222PHE A 225TYR A 258 | D16 A 414 ( 3.6A)D16 A 414 (-4.0A)D16 A 414 (-3.3A)D16 A 414 (-3.6A)UMP A 314 ( 4.4A) | 0.55A | 5nooC-1hvyA:41.3 | 5nooC-1hvyA:62.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ize | ASPARTIC PROTEINASE (Aspergillusoryzae) |
PF00026(Asp) | 5 | ASP A 300LEU A 303GLY A 299PHE A 298TYR A 17 | None | 1.16A | 5nooC-1izeA:undetectable | 5nooC-1izeA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j1w | ISOCITRATEDEHYDROGENASE (Azotobactervinelandii) |
PF03971(IDH) | 4 | ASP A 655GLY A 658PHE A 661TYR A 598 | None | 0.88A | 5nooC-1j1wA:undetectable | 5nooC-1j1wA:19.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1j3j | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00303(Thymidylat_synt) | 4 | ASP C 513LEU C 516GLY C 517TYR C 553 | UMP C 611 (-4.9A)NoneUMP C 611 (-3.5A)UMP C 611 (-4.9A) | 0.70A | 5nooC-1j3jC:39.3 | 5nooC-1j3jC:49.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j5t | INDOLE-3-GLYCEROLPHOSPHATE SYNTHASE (Thermotogamaritima) |
PF00218(IGPS) | 4 | TYR A 64ASP A 68GLY A 67PHE A 65 | None | 0.91A | 5nooC-1j5tA:undetectable | 5nooC-1j5tA:21.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j8s | PYELONEPHRITICADHESIN (Escherichiacoli) |
PF03627(PapG_N) | 4 | TYR A 7ASP A 11LEU A 9GLY A 10 | None | 0.92A | 5nooC-1j8sA:undetectable | 5nooC-1j8sA:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7y | METHIONINE SYNTHASE (Escherichiacoli) |
PF02310(B12-binding)PF02607(B12-binding_2)PF02965(Met_synt_B12) | 4 | TYR A1102LEU A1095GLY A1065PHE A1099 | None | 1.04A | 5nooC-1k7yA:undetectable | 5nooC-1k7yA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nfd | H57 FAB (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | TYR F 35LEU F 4GLY F 104TYR F 3 | None | 1.03A | 5nooC-1nfdF:undetectable | 5nooC-1nfdF:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q6y | HYPOTHETICAL PROTEINYFDW (Escherichiacoli) |
PF02515(CoA_transf_3) | 4 | TYR A 225ASP A 239GLY A 238PHE A 237 | None | 0.83A | 5nooC-1q6yA:undetectable | 5nooC-1q6yA:19.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qgi | PROTEIN(CHITOSANASE) (Bacilluscirculans) |
PF01374(Glyco_hydro_46) | 4 | TYR A 85ASP A 77GLY A 78PHE A 82 | None | 1.06A | 5nooC-1qgiA:undetectable | 5nooC-1qgiA:23.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s35 | SPECTRIN BETA CHAIN,ERYTHROCYTE (Homo sapiens) |
PF00435(Spectrin) | 4 | TYR A1117ASP A1071LEU A1070PHE A1073 | None | 1.03A | 5nooC-1s35A:undetectable | 5nooC-1s35A:22.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1tis | THYMIDYLATE SYNTHASE (Escherichiavirus T4) |
PF00303(Thymidylat_synt) | 5 | ASP A 179LEU A 182GLY A 183PHE A 186TYR A 219 | None | 0.95A | 5nooC-1tisA:29.8 | 5nooC-1tisA:39.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tl2 | PROTEIN(TACHYLECTIN-2) (Tachypleustridentatus) |
PF14517(Tachylectin) | 4 | TYR A 11ASP A 71LEU A 34GLY A 36 | NoneNoneNoneNDG A 237 (-3.0A) | 1.06A | 5nooC-1tl2A:undetectable | 5nooC-1tl2A:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v02 | DHURRINASE (Sorghum bicolor) |
PF00232(Glyco_hydro_1) | 4 | TYR A 166LEU A 150GLY A 156PHE A 157 | None | 1.00A | 5nooC-1v02A:undetectable | 5nooC-1v02A:19.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgm | 378AA LONGHYPOTHETICAL CITRATESYNTHASE (Sulfurisphaeratokodaii) |
PF00285(Citrate_synt) | 4 | TYR A 310ASP A 314GLY A 256PHE A 257 | NoneGOL A 401 ( 4.5A)NoneNone | 0.81A | 5nooC-1vgmA:undetectable | 5nooC-1vgmA:19.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vgp | 373AA LONGHYPOTHETICAL CITRATESYNTHASE (Sulfurisphaeratokodaii) |
PF00285(Citrate_synt) | 4 | TYR A 306ASP A 310GLY A 251PHE A 252 | None | 0.92A | 5nooC-1vgpA:undetectable | 5nooC-1vgpA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xzq | PROBABLE TRNAMODIFICATION GTPASETRME (Thermotogamaritima) |
PF01926(MMR_HSR1)PF10396(TrmE_N)PF12631(MnmE_helical) | 4 | ASP A 119LEU A 120GLY A 431PHE A 434 | None | 1.05A | 5nooC-1xzqA:undetectable | 5nooC-1xzqA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aa4 | PUTATIVEN-ACETYLMANNOSAMINEKINASE (Escherichiacoli) |
PF00480(ROK) | 4 | TYR A 273LEU A 245GLY A 241TYR A 249 | None | 0.98A | 5nooC-2aa4A:undetectable | 5nooC-2aa4A:21.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 4 | ASP A 219LEU A 222GLY A 223TYR A 259 | CB3 A2351 ( 3.6A)CB3 A2351 (-4.1A)CB3 A2351 ( 3.2A)CB3 A2351 ( 4.3A) | 0.76A | 5nooC-2aazA:undetectable | 5nooC-2aazA:49.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2aaz | THYMIDYLATE SYNTHASE (Cryptococcusneoformans) |
PF00303(Thymidylat_synt) | 4 | LEU A 222GLY A 223PHE A 226TYR A 259 | CB3 A2351 (-4.1A)CB3 A2351 ( 3.2A)CB3 A2351 (-3.8A)CB3 A2351 ( 4.3A) | 1.03A | 5nooC-2aazA:undetectable | 5nooC-2aazA:49.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cb1 | O-ACETYL HOMOSERINESULFHYDRYLASE (Thermusthermophilus) |
PF01053(Cys_Met_Meta_PP) | 4 | LEU A 185GLY A 180PHE A 179TYR A 3 | None | 0.86A | 5nooC-2cb1A:undetectable | 5nooC-2cb1A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d6y | PUTATIVE TETR FAMILYREGULATORY PROTEIN (Streptomycescoelicolor) |
PF00440(TetR_N) | 4 | LEU A 55GLY A 53PHE A 56TYR A 46 | None | 0.98A | 5nooC-2d6yA:undetectable | 5nooC-2d6yA:21.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dhb | HEMOGLOBIN (DEOXY)(BETA CHAIN) (Equus caballus) |
PF00042(Globin) | 4 | ASP B 47LEU B 48GLY B 46PHE B 45 | None | 1.05A | 5nooC-2dhbB:undetectable | 5nooC-2dhbB:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2h12 | CITRATE SYNTHASE (Acetobacteraceti) |
PF00285(Citrate_synt) | 4 | TYR A 367ASP A 371GLY A 310PHE A 311 | NoneCMX A5001 (-2.8A)CMX A5001 (-3.4A)None | 0.82A | 5nooC-2h12A:undetectable | 5nooC-2h12A:22.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2h2q | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Trypanosomacruzi) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | ASP A 426LEU A 429GLY A 430PHE A 433TYR A 466 | NoneNone DU A 611 (-3.5A)None DU A 611 (-4.6A) | 0.79A | 5nooC-2h2qA:17.3 | 5nooC-2h2qA:36.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iy8 | PROTEIN PM0188 (Pasteurellamultocida) |
PF11477(PM0188) | 4 | TYR A 358ASP A 140LEU A 200GLY A 142 | NoneNoneNoneCSF A1415 (-3.4A) | 1.06A | 5nooC-2iy8A:undetectable | 5nooC-2iy8A:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j04 | YDR362CP (Saccharomycescerevisiae) |
no annotation | 4 | TYR B 607LEU B 665GLY B 664TYR B 286 | None | 0.98A | 5nooC-2j04B:undetectable | 5nooC-2j04B:19.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2oip | CHAIN A, CRYSTALSTRUCTURE OF DHFR (Cryptosporidiumhominis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | ASP A 426LEU A 429GLY A 430TYR A 466 | CB3 A 604 ( 3.9A)CB3 A 604 ( 4.4A)CB3 A 604 ( 3.4A)UMP A 603 ( 4.3A) | 0.77A | 5nooC-2oipA:20.2 | 5nooC-2oipA:32.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r26 | CITRATE SYNTHASE (Thermoplasmaacidophilum) |
PF00285(Citrate_synt) | 4 | TYR A 313ASP A 317GLY A 259PHE A 260 | NoneCMC A 701 (-2.7A)CMC A 701 (-3.3A)None | 0.86A | 5nooC-2r26A:undetectable | 5nooC-2r26A:20.43 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2tdd | THYMIDYLATE SYNTHASE (Lactobacilluscasei) |
PF00303(Thymidylat_synt) | 4 | ASP A 221LEU A 224GLY A 225TYR A 261 | UFP A 529 (-4.7A)THF A 568 (-3.6A)UFP A 529 ( 4.0A)UFP A 529 (-4.7A) | 0.97A | 5nooC-2tddA:32.2 | 5nooC-2tddA:41.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2tdd | THYMIDYLATE SYNTHASE (Lactobacilluscasei) |
PF00303(Thymidylat_synt) | 4 | LEU A 224GLY A 225PHE A 228TYR A 261 | THF A 568 (-3.6A)UFP A 529 ( 4.0A)THF A 568 (-4.8A)UFP A 529 (-4.7A) | 0.90A | 5nooC-2tddA:32.2 | 5nooC-2tddA:41.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wed | PENICILLOPEPSIN (Penicilliumjanthinellum) |
PF00026(Asp) | 5 | ASP A 300LEU A 303GLY A 299PHE A 298TYR A 17 | None | 1.21A | 5nooC-2wedA:undetectable | 5nooC-2wedA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvl | HYPOTHETICAL PROTEIN (Aquifexaeolicus) |
PF08704(GCD14) | 4 | TYR A 206LEU A 210GLY A 243PHE A 207 | None | 1.03A | 5nooC-2yvlA:undetectable | 5nooC-2yvlA:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z1q | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 4 | TYR A 123LEU A 246GLY A 247PHE A 124 | None | 1.02A | 5nooC-2z1qA:undetectable | 5nooC-2z1qA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z4t | BETA-GALACTOSIDEALPHA-2,6-SIALYLTRANSFERASE (Photobacteriumsp. JT-ISH-224) |
PF11477(PM0188) | 4 | TYR A 452ASP A 231LEU A 293GLY A 233 | NoneNoneNoneGOL A3004 (-3.3A) | 1.04A | 5nooC-2z4tA:undetectable | 5nooC-2z4tA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a0g | HEMOGLOBIN SUBUNITBETA (Cavia porcellus) |
PF00042(Globin) | 4 | ASP B 47LEU B 48GLY B 46PHE B 45 | None | 1.06A | 5nooC-3a0gB:undetectable | 5nooC-3a0gB:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiv | BETA-GLUCOSIDASE (Secale cereale) |
PF00232(Glyco_hydro_1) | 4 | TYR A 168LEU A 152GLY A 158PHE A 159 | None | 1.06A | 5nooC-3aivA:undetectable | 5nooC-3aivA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ayf | NITRIC OXIDEREDUCTASE (Geobacillusstearothermophilus) |
PF00115(COX1) | 4 | TYR A 354LEU A 326GLY A 323PHE A 322 | NoneHEM A 801 (-4.2A)HEM A 801 (-3.5A)None | 0.97A | 5nooC-3ayfA:undetectable | 5nooC-3ayfA:16.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3emy | TRICHODERMA REESEIASPARTIC PROTEASE (Trichodermareesei) |
PF00026(Asp) | 5 | ASP A 304LEU A 307GLY A 303PHE A 302TYR A 14 | None | 1.14A | 5nooC-3emyA:undetectable | 5nooC-3emyA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f0h | AMINOTRANSFERASE ([Eubacterium]rectale) |
PF00266(Aminotran_5) | 4 | TYR A 121LEU A 129GLY A 128PHE A 126 | GOL A 361 (-4.1A)NoneNoneNone | 0.84A | 5nooC-3f0hA:undetectable | 5nooC-3f0hA:20.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ix6 | THYMIDYLATE SYNTHASE (Brucellamelitensis) |
PF00303(Thymidylat_synt) | 4 | ASP A 169LEU A 172GLY A 173TYR A 209 | None | 0.86A | 5nooC-3ix6A:32.9 | 5nooC-3ix6A:38.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4w | UNCHARACTERIZEDPROTEIN BB4693 (Bordetellabronchiseptica) |
PF04909(Amidohydro_2) | 4 | TYR A 87ASP A 5LEU A 8GLY A 62 | None | 1.02A | 5nooC-3k4wA:undetectable | 5nooC-3k4wA:21.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kgb | THYMIDYLATE SYNTHASE1/2 (Encephalitozooncuniculi) |
PF00303(Thymidylat_synt) | 4 | LEU A 200GLY A 201PHE A 204TYR A 237 | None | 0.74A | 5nooC-3kgbA:36.7 | 5nooC-3kgbA:50.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3kjr | DIHYDROFOLATEREDUCTASE/THYMIDYLATE SYNTHASE (Babesia bovis) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | ASP A 416LEU A 419GLY A 420TYR A 456 | None | 0.71A | 5nooC-3kjrA:39.2 | 5nooC-3kjrA:35.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lv4 | GLYCOSIDE HYDROLASEYXIA (Bacilluslicheniformis) |
PF04616(Glyco_hydro_43)PF16369(GH43_C) | 4 | TYR A 331LEU A 233PHE A 322TYR A 241 | None | 0.95A | 5nooC-3lv4A:undetectable | 5nooC-3lv4A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pve | AGRIN, AGRIN PROTEIN (Mus musculus) |
PF00054(Laminin_G_1) | 4 | TYR A1525LEU A1580GLY A1502PHE A1511 | None | 0.97A | 5nooC-3pveA:undetectable | 5nooC-3pveA:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u4t | TPRREPEAT-CONTAININGPROTEIN (Cytophagahutchinsonii) |
PF07719(TPR_2) | 5 | TYR A 378LEU A 405GLY A 403PHE A 390TYR A 441 | None | 1.41A | 5nooC-3u4tA:undetectable | 5nooC-3u4tA:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3um6 | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Plasmodiumfalciparum) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 4 | ASP A 513LEU A 516GLY A 517TYR A 553 | UMP A 611 (-4.9A)NoneUMP A 611 (-3.3A)UMP A 611 (-4.5A) | 0.72A | 5nooC-3um6A:21.3 | 5nooC-3um6A:28.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3v8h | THYMIDYLATE SYNTHASE (Burkholderiathailandensis) |
PF00303(Thymidylat_synt) | 5 | ASP A 217LEU A 220GLY A 221PHE A 224TYR A 257 | NoneNoneNoneNoneCIT A 400 (-4.5A) | 0.84A | 5nooC-3v8hA:33.4 | 5nooC-3v8hA:31.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vre | HEMOGLOBIN SUBUNITBETA/DELTA HYBRID (Mammuthusprimigenius) |
PF00042(Globin) | 4 | ASP B 47LEU B 48GLY B 46PHE B 45 | None | 0.95A | 5nooC-3vreB:undetectable | 5nooC-3vreB:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wq4 | BETA-PRIMEVEROSIDASE (Camelliasinensis) |
PF00232(Glyco_hydro_1) | 4 | ASP A 108LEU A 107GLY A 109PHE A 110 | None | 1.06A | 5nooC-3wq4A:undetectable | 5nooC-3wq4A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zif | HEXON PROTEIN (BovinemastadenovirusB) |
PF01065(Adeno_hexon)PF03678(Adeno_hexon_C) | 4 | ASP A 162LEU A 163PHE A 253TYR A 175 | None | 1.05A | 5nooC-3zifA:undetectable | 5nooC-3zifA:15.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dq1 | THYMIDYLATE SYNTHASE (Staphylococcusaureus) |
PF00303(Thymidylat_synt) | 4 | ASP A 224GLY A 228PHE A 231TYR A 264 | NoneUMP A 501 ( 4.0A)NoneUMP A 501 (-4.2A) | 0.39A | 5nooC-4dq1A:33.1 | 5nooC-4dq1A:44.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dq1 | THYMIDYLATE SYNTHASE (Staphylococcusaureus) |
PF00303(Thymidylat_synt) | 4 | ASP A 224LEU A 227GLY A 228TYR A 264 | NoneNoneUMP A 501 ( 4.0A)UMP A 501 (-4.2A) | 0.81A | 5nooC-4dq1A:33.1 | 5nooC-4dq1A:44.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e5t | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME, C-TERMINALDOMAIN PROTEIN (Labrenziaalexandrii) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 393GLY A 394PHE A 395TYR A 22 | None | 1.06A | 5nooC-4e5tA:undetectable | 5nooC-4e5tA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g4f | TUMOR NECROSISFACTOR LIGANDSUPERFAMILY MEMBER18 (Otolemurgarnettii) |
no annotation | 4 | TYR A 88LEU A 42GLY A 41PHE A 90 | None | 1.05A | 5nooC-4g4fA:undetectable | 5nooC-4g4fA:17.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4h0u | THYMIDYLATE SYNTHASE (Corynebacteriumglutamicum) |
PF00303(Thymidylat_synt) | 4 | ASP A 172LEU A 175GLY A 176TYR A 212 | NoneNoneUMP A 301 (-3.6A)UMP A 301 (-4.5A) | 0.79A | 5nooC-4h0uA:35.5 | 5nooC-4h0uA:42.22 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4iqq | THYMIDYLATE SYNTHASE (Caenorhabditiselegans) |
PF00303(Thymidylat_synt) | 6 | TYR A 82ASP A 220LEU A 223GLY A 224PHE A 227TYR A 260 | D16 A 402 (-3.6A)D16 A 402 ( 4.0A)D16 A 402 (-3.7A)D16 A 402 ( 3.1A)D16 A 402 (-3.2A)D16 A 402 ( 4.2A) | 0.16A | 5nooC-4iqqA:13.5 | 5nooC-4iqqA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jo0 | CMLA (Streptomycesvenezuelae) |
PF12706(Lactamase_B_2) | 4 | TYR A 140ASP A 134GLY A 132PHE A 130 | None | 0.99A | 5nooC-4jo0A:undetectable | 5nooC-4jo0A:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k6j | WINGS APART-LIKEPROTEIN HOMOLOG (Homo sapiens) |
PF07814(WAPL) | 4 | ASP A 822LEU A 821GLY A 820TYR A 875 | None | 1.02A | 5nooC-4k6jA:undetectable | 5nooC-4k6jA:20.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kxb | GLUTAMYLAMINOPEPTIDASE (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | TYR A 915ASP A 468LEU A 884GLY A 919 | None | 1.06A | 5nooC-4kxbA:undetectable | 5nooC-4kxbA:16.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4np4 | TOXIN B (Clostridioidesdifficile) |
PF01473(CW_binding_1) | 4 | TYR A1977LEU A1969GLY A1968PHE A1979 | None | 1.03A | 5nooC-4np4A:undetectable | 5nooC-4np4A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uad | IMPORTIN SUBUNITALPHA-7 (Homo sapiens) |
PF00514(Arm)PF16186(Arm_3) | 4 | TYR A 501ASP A 477LEU A 476GLY A 475 | None | 0.98A | 5nooC-4uadA:undetectable | 5nooC-4uadA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wj3 | ASPARTATE--TRNA(ASP/ASN) LIGASE (Pseudomonasaeruginosa) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon)PF02938(GAD) | 4 | ASP M 537LEU M 536GLY M 535PHE M 534 | None | 0.90A | 5nooC-4wj3M:undetectable | 5nooC-4wj3M:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjm | RIBOKINASE:CARBOHYDRATE KINASE, PFKB (Brucellaabortus) |
PF00294(PfkB) | 4 | LEU A 61GLY A 58PHE A 57TYR A 72 | None | 0.88A | 5nooC-4wjmA:undetectable | 5nooC-4wjmA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4woe | TAUROCYAMINE KINASE (Schistosomamansoni) |
PF00217(ATP-gua_Ptrans)PF02807(ATP-gua_PtransN) | 4 | ASP A 66LEU A 42GLY A 132PHE A 131 | None | 0.91A | 5nooC-4woeA:undetectable | 5nooC-4woeA:18.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4xsc | THYMIDYLATE SYNTHASE (Humanalphaherpesvirus3) |
PF00303(Thymidylat_synt) | 5 | ASP A 206LEU A 209GLY A 210PHE A 213TYR A 246 | NoneNoneBVP A1001 (-3.4A)1PE A1002 (-3.8A)BVP A1001 (-4.5A) | 0.69A | 5nooC-4xscA:38.9 | 5nooC-4xscA:56.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yu4 | HEMOGLOBIN (Helogaleparvula) |
PF00042(Globin) | 4 | ASP B 47LEU B 48GLY B 46PHE B 45 | None | 0.98A | 5nooC-4yu4B:undetectable | 5nooC-4yu4B:19.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5by6 | THYMIDYLATE SYNTHASE (Trichinellaspiralis) |
PF00303(Thymidylat_synt) | 4 | ASP A 212GLY A 216PHE A 219TYR A 252 | NoneUMP A 401 (-3.5A)DTT A 402 ( 4.1A)UMP A 401 (-4.6A) | 0.33A | 5nooC-5by6A:42.5 | 5nooC-5by6A:58.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5by6 | THYMIDYLATE SYNTHASE (Trichinellaspiralis) |
PF00303(Thymidylat_synt) | 4 | ASP A 212LEU A 215GLY A 216TYR A 252 | NoneNoneUMP A 401 (-3.5A)UMP A 401 (-4.6A) | 0.78A | 5nooC-5by6A:42.5 | 5nooC-5by6A:58.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eui | HBB PROTEIN (Ochotonaprinceps) |
PF00042(Globin) | 4 | ASP B 47LEU B 48GLY B 46PHE B 45 | None | 1.04A | 5nooC-5euiB:undetectable | 5nooC-5euiB:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eyg | INOSITOLMONOPHOSPHATASE (Staphylococcusaureus) |
PF00459(Inositol_P) | 4 | TYR A 121ASP A 188LEU A 187GLY A 186 | None | 0.97A | 5nooC-5eygA:undetectable | 5nooC-5eygA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gmt | ALGINATE LYASE (Aplysia kurodai) |
no annotation | 4 | TYR A 140ASP A 156LEU A 167GLY A 168 | None | 1.02A | 5nooC-5gmtA:undetectable | 5nooC-5gmtA:21.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5h3a | ORF70 (Humangammaherpesvirus8) |
PF00303(Thymidylat_synt) | 4 | ASP A 242GLY A 246PHE A 249TYR A 282 | D16 A 401 ( 4.0A)D16 A 401 ( 3.2A)D16 A 401 (-3.4A)UMP A 402 (-4.5A) | 0.15A | 5nooC-5h3aA:41.9 | 5nooC-5h3aA:58.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hct | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | ASP A 307LEU A 310GLY A 306PHE A 305TYR A 17 | None | 1.13A | 5nooC-5hctA:undetectable | 5nooC-5hctA:21.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j7w | THYMIDYLATE SYNTHASE (Enterococcusfaecalis) |
PF00303(Thymidylat_synt) | 5 | ASP A 220LEU A 223GLY A 224PHE A 227TYR A 260 | None | 0.87A | 5nooC-5j7wA:33.1 | 5nooC-5j7wA:43.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kh6 | HISTONE-LYSINEN-METHYLTRANSFERASESETDB1 (Homo sapiens) |
no annotation | 4 | TYR A 389ASP A 299GLY A 300TYR A 277 | 6SU A 513 (-4.9A)None6SU A 513 ( 3.7A)None | 1.03A | 5nooC-5kh6A:undetectable | 5nooC-5kh6A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m4a | NEUTRAL TREHALASE (Saccharomycescerevisiae) |
no annotation | 4 | TYR A 437ASP A 446LEU A 445PHE A 448 | None | 1.02A | 5nooC-5m4aA:undetectable | 5nooC-5m4aA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5x | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA135 (Saccharomycescerevisiae) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF06883(RNA_pol_Rpa2_4) | 5 | ASP B 841LEU B 845GLY B 844PHE B 825TYR B 847 | None | 1.32A | 5nooC-5m5xB:undetectable | 5nooC-5m5xB:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m5x | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA135 (Saccharomycescerevisiae) |
PF00562(RNA_pol_Rpb2_6)PF04560(RNA_pol_Rpb2_7)PF04561(RNA_pol_Rpb2_2)PF04563(RNA_pol_Rpb2_1)PF04565(RNA_pol_Rpb2_3)PF06883(RNA_pol_Rpa2_4) | 5 | TYR B 861ASP B 841LEU B 840GLY B 844TYR B 847 | None | 1.45A | 5nooC-5m5xB:undetectable | 5nooC-5m5xB:14.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mwp | MINERALOCORTICOIDRECEPTOR (Homo sapiens) |
no annotation | 4 | TYR A 869ASP A 929LEU A 928TYR A 980 | None | 1.05A | 5nooC-5mwpA:undetectable | 5nooC-5mwpA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n22 | XECO2 (Xenopus laevis) |
PF13880(Acetyltransf_13) | 4 | TYR A 689ASP A 681GLY A 682PHE A 675 | None | 1.05A | 5nooC-5n22A:undetectable | 5nooC-5n22A:23.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5p60 | ENDOTHIAPEPSIN (Cryphonectriaparasitica) |
PF00026(Asp) | 5 | ASP A 307LEU A 310GLY A 306PHE A 305TYR A 17 | None | 1.12A | 5nooC-5p60A:undetectable | 5nooC-5p60A:21.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t0l | BIFUNCTIONALDIHYDROFOLATEREDUCTASE-THYMIDYLATE SYNTHASE (Toxoplasmagondii) |
PF00186(DHFR_1)PF00303(Thymidylat_synt) | 5 | ASP A 513LEU A 516GLY A 517PHE A 520TYR A 553 | CB3 A 703 ( 3.8A)CB3 A 703 (-3.7A)CB3 A 703 ( 3.0A)CB3 A 703 (-3.8A)UMP A 701 (-4.4A) | 0.48A | 5nooC-5t0lA:40.2 | 5nooC-5t0lA:33.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x4t | PHOTOACTIVATEDADENYLYL CYCLASE (Cyanobacteria) |
PF00211(Guanylate_cyc)PF04940(BLUF) | 4 | TYR A 323LEU A 278GLY A 246PHE A 291 | None | 1.02A | 5nooC-5x4tA:undetectable | 5nooC-5x4tA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ydl | PKS (Streptomycessp. CNQ431) |
no annotation | 4 | TYR A 153LEU A 89GLY A 175PHE A 149 | None | 0.92A | 5nooC-5ydlA:undetectable | 5nooC-5ydlA:13.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6auj | THYMIDYLATE SYNTHASE (Elizabethkingiaanophelis) |
PF00303(Thymidylat_synt) | 4 | ASP A 177GLY A 181PHE A 184TYR A 217 | NonePGE A 301 ( 4.0A)PGE A 301 (-3.7A)None | 0.45A | 5nooC-6aujA:33.3 | 5nooC-6aujA:43.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6auj | THYMIDYLATE SYNTHASE (Elizabethkingiaanophelis) |
PF00303(Thymidylat_synt) | 4 | ASP A 177LEU A 180GLY A 181TYR A 217 | NoneNonePGE A 301 ( 4.0A)None | 0.98A | 5nooC-6aujA:33.3 | 5nooC-6aujA:43.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6cdz | THYMIDYLATE SYNTHASE (Escherichiacoli) |
no annotation | 5 | ASP A 169LEU A 172GLY A 173PHE A 176TYR A 209 | CB3 A 701 ( 3.6A)CB3 A 701 (-3.5A)CB3 A 701 (-3.3A)CB3 A 701 (-3.8A)UMP A 702 ( 4.2A) | 0.53A | 5nooC-6cdzA:35.3 | 5nooC-6cdzA:39.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fkx | ACETYL XYLANESTERASE (metagenome) |
no annotation | 4 | TYR C 93LEU C 190GLY C 189PHE C 210 | None | 0.76A | 5nooC-6fkxC:undetectable | 5nooC-6fkxC:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g3u | - (-) |
no annotation | 4 | ASP A 655GLY A 658PHE A 661TYR A 598 | None | 0.77A | 5nooC-6g3uA:undetectable | 5nooC-6g3uA:undetectable |