SIMILAR PATTERNS OF AMINO ACIDS FOR 5NM5_B_LOCB502_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dys ENDOGLUCANASE

(Humicola
insolens) 		PF01341
(Glyco_hydro_6) 		5 LEU A 259
ASN A 209
ALA A 207
ILE A 203
ILE A 167
 None
 1.29A 5nm5B-1dysA:
2.2		 5nm5B-1dysA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g61 TRANSLATION
INITIATION FACTOR 6

(Methanocaldococcus
jannaschii) 		PF01912
(eIF-6) 		5 LEU A2020
LEU A2107
LEU A2070
ILE A2053
ILE A2084
 None
 0.98A 5nm5B-1g61A:
undetectable		 5nm5B-1g61A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nfi I-KAPPA-B-ALPHA

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2) 		5 LEU E 205
LEU E 187
ALA E 207
ILE E 198
ALA E 190
 None
 1.29A 5nm5B-1nfiE:
undetectable		 5nm5B-1nfiE:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qu9 YJGF PROTEIN

(Escherichia
coli) 		PF01042
(Ribonuc_L-PSP) 		5 LEU A  66
ALA A 125
ASN A  25
ILE A   5
ALA A  64
 None
 1.07A 5nm5B-1qu9A:
undetectable		 5nm5B-1qu9A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1soj CGMP-INHIBITED
3',5'-CYCLIC
PHOSPHODIESTERASE B

(Homo sapiens) 		PF00233
(PDEase_I) 		5 CYH A 929
LEU A 926
ALA A 889
LEU A 885
ILE A 806
 None
 1.07A 5nm5B-1sojA:
undetectable		 5nm5B-1sojA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6p PHENYLALANINE
AMMONIA-LYASE

(Rhodotorula
toruloides) 		PF00221
(Lyase_aromatic) 		5 LEU A 386
ASN A 420
THR A 489
ALA A 506
ALA A 279
 None
 1.09A 5nm5B-1t6pA:
undetectable		 5nm5B-1t6pA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9c PRECORRIN-8X METHYL
MUTASE

(Thermus
thermophilus) 		PF02570
(CbiC) 		5 LEU A  80
LEU A 200
MET A 159
THR A 183
ALA A 199
 None
 1.31A 5nm5B-1v9cA:
4.1		 5nm5B-1v9cA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w1w STRUCTURAL
MAINTENANCE OF
CHROMOSOME 1

(Saccharomyces
cerevisiae) 		PF02463
(SMC_N) 		5 LEU A1075
THR A1135
ILE A1145
ALA A1144
ILE A 157
 None
 1.21A 5nm5B-1w1wA:
undetectable		 5nm5B-1w1wA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xcr HYPOTHETICAL PROTEIN
PTD012

(Homo sapiens) 		PF08925
(DUF1907) 		5 CYH A 140
LEU A 142
THR A 267
ILE A 218
ALA A 131
 None
 0.94A 5nm5B-1xcrA:
undetectable		 5nm5B-1xcrA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z9d URIDYLATE KINASE

(Streptococcus
pyogenes) 		PF00696
(AA_kinase) 		5 LEU A  51
MET A  89
ILE A 225
ALA A 162
ILE A  39
 None
 1.27A 5nm5B-1z9dA:
undetectable		 5nm5B-1z9dA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b92 INTERFERON-INDUCED
GUANYLATE-BINDING
PROTEIN 1

(Homo sapiens) 		PF02263
(GBP)
PF02841
(GBP_C) 		5 LEU A  13
MET A  38
ILE A  30
ALA A  27
ILE A  34
 LEU  A  13 ( 0.6A)
MET  A  38 ( 0.0A)
ILE  A  30 ( 0.6A)
ALA  A  27 ( 0.0A)
ILE  A  34 ( 0.6A)
 1.33A 5nm5B-2b92A:
undetectable		 5nm5B-2b92A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ffh PROTEIN (FFH)

(Thermus
aquaticus) 		PF00448
(SRP54)
PF02881
(SRP54_N)
PF02978
(SRP_SPB) 		5 LEU A   5
LEU A 292
ILE A  34
ALA A  37
ILE A  13
 None
 1.22A 5nm5B-2ffhA:
3.9		 5nm5B-2ffhA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fj0 CARBOXYLIC ESTER
HYDROLASE

(Manduca sexta) 		PF00135
(COesterase) 		5 LEU A 185
LEU A 292
MET A 295
ALA A 282
ILE A 278
 None
 0.96A 5nm5B-2fj0A:
3.0		 5nm5B-2fj0A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jk0 L-ASPARAGINASE

(Pectobacterium
carotovorum) 		PF00710
(Asparaginase) 		5 LEU A  49
LEU A 135
ILE A   7
ALA A  50
ILE A   9
 None
 0.89A 5nm5B-2jk0A:
2.2		 5nm5B-2jk0A:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kan UNCHARACTERIZED
PROTEIN AR3433A

(Arabidopsis
thaliana) 		PF00240
(ubiquitin) 		5 LEU A  71
LEU A  57
MET A  55
THR A  50
ILE A  44
 None
 1.29A 5nm5B-2kanA:
undetectable		 5nm5B-2kanA:
13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ng1 SIGNAL SEQUENCE
RECOGNITION PROTEIN
FFH

(Thermus
aquaticus) 		PF00448
(SRP54)
PF02881
(SRP54_N) 		5 LEU A   5
LEU A 292
ILE A  34
ALA A  37
ILE A  13
 None
 1.28A 5nm5B-2ng1A:
3.8		 5nm5B-2ng1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7p RIBOFLAVIN
BIOSYNTHESIS PROTEIN
RIBD

(Escherichia
coli) 		PF00383
(dCMP_cyt_deam_1)
PF01872
(RibD_C) 		5 LEU A 288
ALA A 189
LEU A 191
THR A 196
ILE A 232
 None
None
None
NAP  A 402 (-3.3A)
NAP  A 402 ( 4.8A)
 1.21A 5nm5B-2o7pA:
undetectable		 5nm5B-2o7pA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oi6 BIFUNCTIONAL PROTEIN
GLMU

(Escherichia
coli) 		PF00132
(Hexapep)
PF12804
(NTP_transf_3) 		5 LEU A 338
LEU A 367
ALA A 361
ALA A 342
ILE A 378
 None
 0.85A 5nm5B-2oi6A:
undetectable		 5nm5B-2oi6A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3v INOSITOL-1-MONOPHOSP
HATASE

(Thermotoga
maritima) 		PF00459
(Inositol_P) 		5 LEU A1179
ALA A1113
ALA A1186
ILE A1208
ILE A1135
 None
 0.91A 5nm5B-2p3vA:
undetectable		 5nm5B-2p3vA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qc3 MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Mycobacterium
tuberculosis) 		PF00698
(Acyl_transf_1) 		5 LEU A 222
THR A 263
ALA A   3
ALA A  88
ILE A 265
 None
 1.25A 5nm5B-2qc3A:
undetectable		 5nm5B-2qc3A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qo3 ERYAII ERYTHROMYCIN
POLYKETIDE SYNTHASE
MODULES 3 AND 4

(Saccharopolyspora
erythraea) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		5 ALA A 208
LEU A 151
THR A 127
ALA A 224
ILE A 185
 None
 0.82A 5nm5B-2qo3A:
undetectable		 5nm5B-2qo3A:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtn NICOTINATE
(NICOTINAMIDE)
NUCLEOTIDE
ADENYLYLTRANSFERASE

(Bacillus
anthracis) 		PF01467
(CTP_transf_like) 		5 LEU A  19
ALA A  63
LEU A  60
ILE A   7
ALA A  22
 None
 1.31A 5nm5B-2qtnA:
undetectable		 5nm5B-2qtnA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v9v SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR

(Moorella
thermoacetica) 		PF09105
(SelB-wing_1)
PF09106
(SelB-wing_2) 		5 LEU A 405
LEU A 414
MET A 417
ALA A 403
ILE A 387
 None
 0.99A 5nm5B-2v9vA:
undetectable		 5nm5B-2v9vA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vmd DISCOIDIN-2

(Dictyostelium
discoideum) 		PF00754
(F5_F8_type_C)
PF09458
(H_lectin) 		5 CYH A  10
LEU A  11
THR A  96
ALA A 153
ILE A 134
 None
 1.21A 5nm5B-2vmdA:
undetectable		 5nm5B-2vmdA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w2g NON-STRUCTURAL
PROTEIN 3

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF11633
(SUD-M) 		5 LEU A 504
LEU A 412
THR A 450
ILE A 459
ALA A 474
 None
 1.31A 5nm5B-2w2gA:
undetectable		 5nm5B-2w2gA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wiz ARCHAEAL HJC

(Archaeoglobus
fulgidus) 		PF01870
(Hjc) 		5 ALA A  23
LEU A  48
ALA A 124
ILE A 120
ALA A  19
 None
 1.05A 5nm5B-2wizA:
undetectable		 5nm5B-2wizA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yp2 HEMAGGLUTININ

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		5 LEU A 439
ALA A 373
THR A  40
ALA A 317
ILE A 437
 None
None
NAG  A 802 ( 4.0A)
None
None
 1.07A 5nm5B-2yp2A:
undetectable		 5nm5B-2yp2A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ypq PHOSPHO-2-DEHYDRO-3-
DEOXYHEPTONATE
ALDOLASE AROG

(Mycobacterium
tuberculosis) 		PF01474
(DAHP_synth_2) 		5 LEU A 186
LEU A 107
ALA A 192
ALA A 125
ILE A 127
 None
TRP  A1464 ( 4.4A)
TRP  A1464 (-4.6A)
None
None
 1.30A 5nm5B-2ypqA:
undetectable		 5nm5B-2ypqA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a64 CELLOBIOHYDROLASE

(Coprinopsis
cinerea) 		PF01341
(Glyco_hydro_6) 		5 LEU A  22
LEU A  93
THR A  67
ILE A  75
ILE A  71
 None
 1.27A 5nm5B-3a64A:
2.8		 5nm5B-3a64A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asa LL-DIAMINOPIMELATE
AMINOTRANSFERASE

(Chlamydia
trachomatis) 		PF00155
(Aminotran_1_2) 		5 CYH A 227
LEU A 254
THR A 120
ILE A 199
ALA A 192
 None
 1.33A 5nm5B-3asaA:
undetectable		 5nm5B-3asaA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bz5 INTERNALIN-J

(Listeria
monocytogenes) 		PF12799
(LRR_4) 		5 LEU A 374
ASN A 378
ALA A 358
ALA A 333
ILE A 360
 None
 0.95A 5nm5B-3bz5A:
undetectable		 5nm5B-3bz5A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cuq VACUOLAR-SORTING
PROTEIN SNF8

(Homo sapiens) 		PF04157
(EAP30) 		5 LEU A 236
ALA A 222
LEU A 213
ALA A 187
ILE A 198
 None
 1.07A 5nm5B-3cuqA:
undetectable		 5nm5B-3cuqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1j ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF05362
(Lon_C)
PF13654
(AAA_32) 		5 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.84A 5nm5B-3k1jA:
undetectable		 5nm5B-3k1jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k53 FERROUS IRON
TRANSPORT PROTEIN B

(Pyrococcus
furiosus) 		PF02421
(FeoB_N) 		5 LEU A  63
ASN A  81
THR A   5
ALA A   7
ILE A  85
 None
 1.30A 5nm5B-3k53A:
2.8		 5nm5B-3k53A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3klb PUTATIVE
FLAVOPROTEIN

(Bacteroides
fragilis) 		PF12682
(Flavodoxin_4) 		5 LEU A 128
ASN A 127
ALA A  92
ALA A 114
ILE A  96
 None
 1.15A 5nm5B-3klbA:
4.7		 5nm5B-3klbA:
17.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r3s OXIDOREDUCTASE

(Salmonella
enterica) 		PF13561
(adh_short_C2) 		5 ALA A  68
THR A 184
ALA A 133
ILE A 131
ILE A 182
 None
NAD  A 300 ( 4.4A)
None
None
None
 1.07A 5nm5B-3r3sA:
7.1		 5nm5B-3r3sA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg1 CD180 MOLECULE

(Bos taurus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		5 LEU A 525
LEU A 498
LEU A 503
THR A 459
ILE A 486
 None
 1.05A 5nm5B-3rg1A:
undetectable		 5nm5B-3rg1A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3twd BIFUNCTIONAL PROTEIN
GLMU

(Escherichia
coli) 		PF00132
(Hexapep) 		5 LEU A 338
LEU A 367
ALA A 361
ALA A 342
ILE A 378
 None
 0.78A 5nm5B-3twdA:
undetectable		 5nm5B-3twdA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubr CYTOCHROME C-552

(Shewanella
oneidensis) 		PF02335
(Cytochrom_C552) 		6 LEU A  75
LEU A 437
ALA A  77
ILE A 427
ALA A 433
ILE A 424
 None
 1.48A 5nm5B-3ubrA:
undetectable		 5nm5B-3ubrA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3unv ADMH

(Pantoea
agglomerans) 		PF00221
(Lyase_aromatic) 		5 CYH A 486
LEU A 412
ALA A 490
LEU A 254
ILE A 396
 None
 1.06A 5nm5B-3unvA:
undetectable		 5nm5B-3unvA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wtc PUTATIVE
OXIDOREDUCTASE

(Gluconobacter
oxydans) 		PF00106
(adh_short) 		5 LEU A  73
THR A  11
ALA A   9
ILE A   7
ILE A  33
 None
 0.99A 5nm5B-3wtcA:
7.1		 5nm5B-3wtcA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zh4 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Streptococcus
pneumoniae) 		PF00275
(EPSP_synthase) 		5 LEU A 361
ALA A 380
LEU A 377
ILE A 346
ALA A 344
 None
 1.29A 5nm5B-3zh4A:
undetectable		 5nm5B-3zh4A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyo LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 4B

(Mus musculus) 		PF00560
(LRR_1)
PF07679
(I-set)
PF13855
(LRR_8) 		5 LEU A 284
LEU A 236
LEU A 262
ASN A 241
ILE A 246
 None
 1.18A 5nm5B-3zyoA:
undetectable		 5nm5B-3zyoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4an7 TRYPSIN INHIBITOR

(Tamarindus
indica) 		PF00197
(Kunitz_legume) 		5 LEU B  76
ASN B  77
ILE B  67
ALA B  65
ILE B  70
 None
 1.32A 5nm5B-4an7B:
undetectable		 5nm5B-4an7B:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bb9 GLUCOKINASE
REGULATORY PROTEIN

(Homo sapiens) 		no annotation 5 LEU A  94
ALA A 277
LEU A 274
ILE A 174
ILE A 176
 None
 1.32A 5nm5B-4bb9A:
4.7		 5nm5B-4bb9A:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cns DIHYDROPYRIMIDINASE-
LIKE 3

(Homo sapiens) 		PF01979
(Amidohydro_1) 		5 LEU A  17
MET A  37
ILE A 411
ALA A  60
ILE A 447
 None
 1.32A 5nm5B-4cnsA:
2.4		 5nm5B-4cnsA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7p SUPEROXIDE REDUCTASE

(Giardia
intestinalis) 		PF01880
(Desulfoferrodox) 		5 CYH A  34
ASN A 100
ILE A  51
ALA A  97
ILE A  71
 None
 1.10A 5nm5B-4d7pA:
undetectable		 5nm5B-4d7pA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e51 HISTIDINE--TRNA
LIGASE

(Burkholderia
thailandensis) 		PF03129
(HGTP_anticodon)
PF13393
(tRNA-synt_His) 		5 LEU A 140
ALA A 308
LEU A 297
ILE A 100
ALA A  99
 None
 0.88A 5nm5B-4e51A:
undetectable		 5nm5B-4e51A:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ew6 D-GALACTOSE-1-DEHYDR
OGENASE PROTEIN

(Rhizobium etli) 		PF01408
(GFO_IDH_MocA) 		5 LEU A  65
ALA A  75
MET A  53
ALA A   7
ILE A  60
 None
 1.13A 5nm5B-4ew6A:
4.5		 5nm5B-4ew6A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fq0 FLAGELLAR MOTOR
SWITCH PROTEIN

(Helicobacter
pylori) 		PF14841
(FliG_M) 		5 LEU C 195
LEU C 122
ASN C 153
ILE C 134
ALA C 131
 None
 1.34A 5nm5B-4fq0C:
undetectable		 5nm5B-4fq0C:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g1g MATRIX PROTEIN

(Avian
avulavirus 1) 		PF00661
(Matrix) 		5 LEU A 206
LEU A 204
MET A 242
ALA A 282
ILE A 261
 None
 1.19A 5nm5B-4g1gA:
undetectable		 5nm5B-4g1gA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6q PROLINE
DEHYDROGENASE

(Deinococcus
radiodurans) 		PF01619
(Pro_dh) 		5 LEU A  82
LEU A 279
ASN A  58
ILE A  44
ALA A  86
 None
 1.15A 5nm5B-4h6qA:
2.9		 5nm5B-4h6qA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hb9 SIMILARITIES WITH
PROBABLE
MONOOXYGENASE

(Photorhabdus
laumondii) 		PF01494
(FAD_binding_3) 		5 LEU A 334
LEU A 315
ALA A 337
THR A 124
ALA A 160
 None
 1.08A 5nm5B-4hb9A:
undetectable		 5nm5B-4hb9A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhu OR280

(synthetic
construct) 		no annotation 5 LEU A  20
LEU A  65
ILE A   6
ALA A  62
ILE A  47
 AE4  A 201 (-4.8A)
None
None
None
None
 1.06A 5nm5B-4hhuA:
undetectable		 5nm5B-4hhuA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhu OR280

(synthetic
construct) 		no annotation 5 LEU A 101
LEU A 146
ILE A  87
ALA A 143
ILE A 128
 None
 1.19A 5nm5B-4hhuA:
undetectable		 5nm5B-4hhuA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hrl DESIGNED ANKYRIN
REPEAT PROTEIN 9_29

(synthetic
construct) 		PF12796
(Ank_2) 		5 LEU A  83
ALA A 103
ASN A 134
ILE A  94
ALA A  86
 None
 1.24A 5nm5B-4hrlA:
undetectable		 5nm5B-4hrlA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i2w PROTEIN UNC-45

(Caenorhabditis
elegans) 		PF11701
(UNC45-central) 		5 LEU A 753
LEU A 799
THR A 812
ILE A 770
ILE A 776
 None
 1.17A 5nm5B-4i2wA:
undetectable		 5nm5B-4i2wA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iau BETA-GAMMA-CRYSTALLI
N

(Geodia cydonium) 		PF00030
(Crystall) 		5 LEU A 101
LEU A 156
ALA A 116
ILE A 118
ALA A  86
 None
 0.97A 5nm5B-4iauA:
undetectable		 5nm5B-4iauA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iqz DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA'

(Escherichia
coli) 		no annotation 5 LEU A 198
LEU A 190
ALA A 211
ALA A 166
ILE A 169
 None
 1.09A 5nm5B-4iqzA:
undetectable		 5nm5B-4iqzA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpg MEMBRANE-ANCHORED
MYCOSIN MYCP1

(Mycolicibacterium
smegmatis) 		PF00082
(Peptidase_S8) 		5 LEU A 184
LEU A 153
ALA A 192
ILE A 199
ALA A  89
 None
 1.27A 5nm5B-4kpgA:
2.6		 5nm5B-4kpgA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m1z MEMBRANE-ANCHORED
MYCOSIN MYCP1

(Mycolicibacterium
smegmatis) 		PF00082
(Peptidase_S8) 		5 LEU A 184
LEU A 153
ALA A 192
ILE A 199
ALA A  89
 None
 1.30A 5nm5B-4m1zA:
2.6		 5nm5B-4m1zA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0g PROTEIN PHOSPHATASE
2C 37

(Arabidopsis
thaliana) 		PF00481
(PP2C) 		5 CYH A 321
LEU A 389
LEU A 346
ASN A 360
ALA A 342
 None
 1.29A 5nm5B-4n0gA:
undetectable		 5nm5B-4n0gA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nez ENGINEERED PROTEIN
OR276

(synthetic
construct) 		no annotation 5 LEU A 103
LEU A 148
ILE A  89
ALA A 145
ILE A 130
 None
 1.14A 5nm5B-4nezA:
undetectable		 5nm5B-4nezA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pbv NT-3 GROWTH FACTOR
RECEPTOR

(Gallus gallus) 		PF00047
(ig)
PF13855
(LRR_8)
PF16920
(TPKR_C2) 		5 LEU A 146
LEU A  94
ASN A 117
ILE A 132
ILE A 110
 None
 1.04A 5nm5B-4pbvA:
undetectable		 5nm5B-4pbvA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qsl PYRUVATE CARBOXYLASE

(Listeria
monocytogenes) 		no annotation 5 LEU H  88
LEU H   8
ALA H  10
ILE H  70
ALA H  73
 None
 1.17A 5nm5B-4qslH:
undetectable		 5nm5B-4qslH:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r7z CELL DIVISION
CONTROL PROTEIN 21

(Pyrococcus
furiosus) 		PF00493
(MCM) 		5 LEU A 325
LEU A 338
LEU A 761
MET A 764
ILE A 772
 None
 1.14A 5nm5B-4r7zA:
undetectable		 5nm5B-4r7zA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tpg PROTON:OLIGOPEPTIDE
SYMPORTER POT FAMILY

(Shewanella
oneidensis) 		PF00854
(PTR2) 		5 LEU A 160
LEU A  34
ALA A 181
ASN A 169
ALA A 323
 None
 0.92A 5nm5B-4tpgA:
undetectable		 5nm5B-4tpgA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ug4 CHOLINE SULFATASE

(Sinorhizobium
meliloti) 		PF00884
(Sulfatase)
PF12411
(Choline_sulf_C) 		5 ALA A  36
LEU A  34
ILE A 291
ALA A 324
ILE A  11
 None
 1.22A 5nm5B-4ug4A:
undetectable		 5nm5B-4ug4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wyi MONOGALACTOSYLDIACYL
GLYCEROL SYNTHASE 1,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF04101
(Glyco_tran_28_C)
PF06925
(MGDG_synth) 		5 LEU A 493
MET A 421
ALA A 439
ALA A 500
ILE A 427
 None
 1.19A 5nm5B-4wyiA:
5.1		 5nm5B-4wyiA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yeb FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 3

(Mus musculus) 		PF13855
(LRR_8) 		5 LEU B 180
LEU B 133
LEU B 161
ASN B 138
ILE B 145
 None
 1.23A 5nm5B-4yebB:
undetectable		 5nm5B-4yebB:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yhg GH5

(Bacteroidetes
bacterium AC2a) 		PF00150
(Cellulase) 		5 ALA A  99
LEU A  58
ASN A  56
ALA A  50
ILE A 354
 None
 1.13A 5nm5B-4yhgA:
2.8		 5nm5B-4yhgA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zpx ATP-DEPENDENT
PROTEASE LON

(Thermococcus
onnurineus) 		PF01078
(Mg_chelatase)
PF13654
(AAA_32) 		5 LEU A 208
ALA A 261
LEU A 258
ALA A 237
ILE A 244
 None
 0.87A 5nm5B-4zpxA:
undetectable		 5nm5B-4zpxA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a29 EXOPOLYGALACTURONATE
LYASE

(Vibrio
vulnificus) 		PF06917
(Pectate_lyase_2) 		5 LEU A 360
LEU A 431
ASN A 434
MET A 435
ALA A 366
 None
EDO  A1579 ( 4.3A)
None
None
None
 1.16A 5nm5B-5a29A:
undetectable		 5nm5B-5a29A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cw9 DE NOVO DESIGNED
FERREDOXIN-FERREDOXI
N DOMAIN INSERTION
PROTEIN

(synthetic
construct) 		no annotation 5 LEU A  53
LEU A  98
ILE A  39
ALA A  95
ILE A  80
 None
 1.11A 5nm5B-5cw9A:
undetectable		 5nm5B-5cw9A:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cwi DESIGNED HELICAL
REPEAT PROTEIN

(synthetic
construct) 		no annotation 5 CYH A 127
LEU A 114
ASN A 180
ALA A 184
ILE A 188
 None
 1.16A 5nm5B-5cwiA:
undetectable		 5nm5B-5cwiA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dyq YD REPEAT-CONTAINING
PROTEIN

(Verrucosispora
maris) 		no annotation 5 LEU A  45
ALA A 135
MET A 139
ALA A 108
ILE A  87
 None
 1.25A 5nm5B-5dyqA:
undetectable		 5nm5B-5dyqA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e1v POLYKETIDE SYNTHASE
PKSL

(Bacillus
subtilis) 		no annotation 5 LEU B  62
ALA B  94
ILE B  92
ALA B 114
ILE B  80
 None
 0.94A 5nm5B-5e1vB:
undetectable		 5nm5B-5e1vB:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exe OXALATE
OXIDOREDUCTASE
SUBUNIT DELTA

(Moorella
thermoacetica) 		PF00037
(Fer4)
PF01558
(POR) 		5 LEU B 186
ALA B  38
ILE B  31
ALA B 171
ILE B  15
 None
 1.27A 5nm5B-5exeB:
undetectable		 5nm5B-5exeB:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		5 LEU A 494
MET A 436
ILE A 215
ALA A 212
ILE A 219
 None
 0.88A 5nm5B-5fkuA:
undetectable		 5nm5B-5fkuA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4v GLUTAMATE--TRNA
LIGASE

(Xanthomonas
oryzae) 		no annotation 5 LEU A 395
ALA A 391
LEU A 388
ILE A 432
ALA A 453
 None
 1.28A 5nm5B-5h4vA:
undetectable		 5nm5B-5h4vA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hqn SPHINGOMYELIN
PHOSPHODIESTERASE

(Mus musculus) 		PF00149
(Metallophos) 		5 LEU A 373
LEU A 367
THR A 274
ILE A 376
ALA A 366
 None
 1.30A 5nm5B-5hqnA:
undetectable		 5nm5B-5hqnA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i4e MYOSIN-14,ALPHA-ACTI
NIN A

(Dictyostelium
discoideum;
Homo sapiens) 		PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N) 		5 LEU A 463
ALA A 241
ILE A 268
ALA A 279
ILE A 476
 None
 0.98A 5nm5B-5i4eA:
undetectable		 5nm5B-5i4eA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ieb SENSORY TRANSDUCTION
REGULATORY PROTEIN

(Sphingomonas
melonis) 		PF00072
(Response_reg) 		5 ALA A 115
LEU A 113
ALA A  52
ILE A  54
ILE A   7
 None
 1.27A 5nm5B-5iebA:
3.2		 5nm5B-5iebA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5le9 DD_OFF7_09_3G124

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2) 		5 LEU A  51
ALA A  71
ASN A 102
ILE A  62
ALA A  54
 None
 1.23A 5nm5B-5le9A:
undetectable		 5nm5B-5le9A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5le9 DD_OFF7_09_3G124

(synthetic
construct) 		PF00023
(Ank)
PF12796
(Ank_2) 		5 LEU A 206
ALA A 226
ASN A 257
ILE A 217
ALA A 209
 None
 1.24A 5nm5B-5le9A:
undetectable		 5nm5B-5le9A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5leb DDD_D12_06_D12_06_D1
2

(synthetic
construct) 		PF12796
(Ank_2)
PF13857
(Ank_5) 		5 LEU A  84
ALA A 104
ASN A 135
ILE A  95
ALA A  87
 None
 1.25A 5nm5B-5lebA:
undetectable		 5nm5B-5lebA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lm7 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA

(Escherichia
coli) 		PF00575
(S1)
PF08529
(NusA_N)
PF13184
(KH_5) 		5 LEU A 266
ALA A 234
ILE A 236
ALA A 226
ILE A 271
 None
 1.05A 5nm5B-5lm7A:
undetectable		 5nm5B-5lm7A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mad 3G61

(synthetic
construct) 		no annotation 5 LEU A  83
ALA A 103
ASN A 134
ILE A  94
ALA A  86
 None
 1.30A 5nm5B-5madA:
undetectable		 5nm5B-5madA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mak R7

(synthetic
construct) 		no annotation 5 LEU A  51
ALA A  71
ASN A 102
ILE A  62
ALA A  54
 None
 1.24A 5nm5B-5makA:
undetectable		 5nm5B-5makA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mdh MALATE DEHYDROGENASE

(Sus scrofa) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		5 LEU A  64
LEU A  53
LEU A  20
ALA A  11
ALA A  69
 None
 1.26A 5nm5B-5mdhA:
undetectable		 5nm5B-5mdhA:
22.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe) 		no annotation 5 MET A 257
THR A 311
ALA A 313
ALA A 351
ILE A 367
 None
 0.57A 5nm5B-5mjsA:
53.8		 5nm5B-5mjsA:
58.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5my0 FATTY ACID SYNTHASE

(Mus musculus) 		no annotation 5 LEU B 165
LEU B 341
ALA B 244
ILE B 246
ILE B   6
 None
 1.15A 5nm5B-5my0B:
undetectable		 5nm5B-5my0B:
10.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens) 		no annotation 5 LEU B 255
ASN B 258
MET B 259
THR B 314
ILE B 378
 None
 0.93A 5nm5B-5n5nB:
54.6		 5nm5B-5n5nB:
97.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens) 		no annotation 5 LEU B 255
MET B 259
THR B 314
ALA B 316
ILE B 378
 None
 1.05A 5nm5B-5n5nB:
54.6		 5nm5B-5n5nB:
97.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens) 		no annotation 5 MET B 259
THR B 314
ALA B 316
ALA B 354
ILE B 378
 None
 0.76A 5nm5B-5n5nB:
54.6		 5nm5B-5n5nB:
97.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o2s DARPIN K27

(Homo sapiens) 		PF00023
(Ank)
PF12796
(Ank_2) 		5 LEU B  94
ALA B 114
ASN B 145
ILE B 105
ALA B  97
 None
 1.25A 5nm5B-5o2sB:
undetectable		 5nm5B-5o2sB:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojs TRANSCRIPTION-ASSOCI
ATED PROTEIN 1

(Saccharomyces
cerevisiae) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT) 		5 LEU T2027
ALA T2032
ILE T2029
ALA T2028
ILE T2123
 None
 1.33A 5nm5B-5ojsT:
undetectable		 5nm5B-5ojsT:
7.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tvg ALPHA,ALPHA-TREHALOS
E-PHOSPHATE SYNTHASE
(UDP-FORMING)

(Burkholderia
vietnamiensis) 		PF00982
(Glyco_transf_20) 		5 LEU A 442
LEU A 437
LEU A 368
ILE A 234
ALA A 375
 None
None
UDP  A 501 (-3.9A)
GOL  A 503 (-4.4A)
None
 1.15A 5nm5B-5tvgA:
undetectable		 5nm5B-5tvgA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9j PRHC

(Penicillium
brasilianum) 		no annotation 5 LEU A 109
ASN A 108
ILE A  89
ALA A  14
ILE A 111
 None
 0.97A 5nm5B-5x9jA:
undetectable		 5nm5B-5x9jA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xex POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Staphylococcus
aureus) 		no annotation 5 LEU A 202
LEU A 177
ALA A 204
ILE A 509
ALA A 191
 None
 1.34A 5nm5B-5xexA:
undetectable		 5nm5B-5xexA:
21.49