SIMILAR PATTERNS OF AMINO ACIDS FOR 5ND4_B_TA1B601_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k1b B-CELL LYMPHOMA
3-ENCODED PROTEIN


(Homo sapiens)
PF00023
(Ank)
PF12796
(Ank_2)
5 VAL A 242
GLU A 245
LEU A 272
ALA A 275
LEU A 281
None
1.14A 5nd4B-1k1bA:
undetectable
5nd4B-1k1bA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q5d P450 EPOXIDASE

(Sorangium
cellulosum)
PF00067
(p450)
5 VAL A 191
ASP A 192
GLU A 193
LEU A 183
ALA A 182
None
None
None
EPB  A 450 (-4.3A)
None
1.05A 5nd4B-1q5dA:
undetectable
5nd4B-1q5dA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s2j PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA


(Drosophila
melanogaster)
PF01510
(Amidase_2)
5 ASP A 122
LEU A 132
ALA A 128
PRO A 120
LEU A 163
None
1.22A 5nd4B-1s2jA:
undetectable
5nd4B-1s2jA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sxr PEPTIDOGLYCAN
RECOGNITION PROTEIN
SA CG11709-PA


(Drosophila
melanogaster)
PF01510
(Amidase_2)
5 ASP A 122
LEU A 132
ALA A 128
PRO A 120
LEU A 163
None
1.23A 5nd4B-1sxrA:
undetectable
5nd4B-1sxrA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2l PEROXIDASE/CATALASE
HPI


(Escherichia
coli)
PF00141
(peroxidase)
5 VAL A 512
GLU A 514
ALA A 509
ARG A 498
LEU A 492
None
1.20A 5nd4B-1u2lA:
undetectable
5nd4B-1u2lA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uz5 402AA LONG
HYPOTHETICAL
MOLYBDOPTERIN
BIOSYNTHESIS MOEA
PROTEIN


(Pyrococcus
horikoshii)
PF00994
(MoCF_biosynth)
PF03453
(MoeA_N)
PF03454
(MoeA_C)
5 VAL A 394
GLU A 395
LEU A 358
ALA A 334
LEU A 398
None
1.09A 5nd4B-1uz5A:
undetectable
5nd4B-1uz5A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w9x ALPHA AMYLASE

(Bacillus
halmapalus)
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
5 ASP A 308
LEU A 297
ALA A 300
SER A 303
PHE A 348
None
1.24A 5nd4B-1w9xA:
3.0
5nd4B-1w9xA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdt ELONGATION FACTOR G
HOMOLOG


(Thermus
thermophilus)
PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03764
(EFG_IV)
PF14492
(EFG_II)
5 GLU A 408
HIS A 432
LEU A 433
ALA A 436
LEU A 406
None
1.08A 5nd4B-1wdtA:
undetectable
5nd4B-1wdtA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdw TRYPTOPHAN SYNTHASE
BETA CHAIN 1


(Pyrococcus
furiosus)
PF00291
(PALP)
5 VAL B 304
HIS B 308
LEU B 311
SER B 279
PRO B 193
None
1.32A 5nd4B-1wdwB:
undetectable
5nd4B-1wdwB:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyt GLYCINE
DEHYDROGENASE
(DECARBOXYLATING)
SUBUNIT 1


(Thermus
thermophilus)
PF02347
(GDC-P)
5 ASP A 385
LEU A 380
ALA A 413
PHE A 415
LEU A 393
None
1.24A 5nd4B-1wytA:
2.1
5nd4B-1wytA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x1b CRTF-RELATED PROTEIN

(Chlorobaculum
tepidum)
PF00891
(Methyltransf_2)
5 VAL A 208
GLU A 210
LEU A 201
ALA A 204
ARG A 140
None
None
SAH  A4261 (-4.0A)
None
None
1.27A 5nd4B-1x1bA:
undetectable
5nd4B-1x1bA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yts YERSINIA PROTEIN
TYROSINE PHOSPHATASE


(Yersinia
enterocolitica)
PF00102
(Y_phosphatase)
5 VAL A 372
ASP A 373
LEU A 282
ALA A 283
ARG A 398
None
1.30A 5nd4B-1ytsA:
undetectable
5nd4B-1ytsA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zye THIOREDOXIN-DEPENDEN
T PEROXIDE REDUCTASE


(Bos taurus)
PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C)
5 VAL A  73
ASP A  74
LEU A 115
ALA A 121
SER A 108
None
1.31A 5nd4B-1zyeA:
undetectable
5nd4B-1zyeA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c6r DNA-BINDING STRESS
RESPONSE PROTEIN,
DPS FAMILY


(Deinococcus
radiodurans)
PF00210
(Ferritin)
5 GLU A  58
LEU A  64
ALA A  61
ARG A 113
LEU A  56
None
1.26A 5nd4B-2c6rA:
undetectable
5nd4B-2c6rA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2die AMYLASE

(Bacillus sp.
(in: Bacteria))
PF00128
(Alpha-amylase)
PF09154
(DUF1939)
5 ASP A 308
LEU A 297
ALA A 300
SER A 303
PHE A 348
None
1.19A 5nd4B-2dieA:
3.2
5nd4B-2dieA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eid GALACTOSE OXIDASE

(Fusarium
graminearum)
PF00754
(F5_F8_type_C)
PF01344
(Kelch_1)
PF09118
(DUF1929)
5 LEU A 620
ALA A 632
PHE A 621
ARG A 575
LEU A 501
None
1.03A 5nd4B-2eidA:
undetectable
5nd4B-2eidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ghp U4/U6
SNRNA-ASSOCIATED
SPLICING FACTOR
PRP24


(Saccharomyces
cerevisiae)
PF00076
(RRM_1)
5 VAL A 165
ASP A 164
LEU A 178
ARG A 268
ARG A 134
None
1.20A 5nd4B-2ghpA:
undetectable
5nd4B-2ghpA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gz4 HYPOTHETICAL PROTEIN
ATU1052


(Agrobacterium
fabrum)
no annotation 5 ASP A  77
GLU A  78
HIS A 119
ALA A 128
ARG A 135
None
1.15A 5nd4B-2gz4A:
undetectable
5nd4B-2gz4A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
5 VAL A 480
GLU A 463
HIS A 400
ALA A 461
LEU A 380
None
1.16A 5nd4B-2iujA:
undetectable
5nd4B-2iujA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iuj LIPOXYGENASE L-5

(Glycine max)
PF00305
(Lipoxygenase)
PF01477
(PLAT)
5 VAL A 480
GLU A 463
LEU A 460
ALA A 461
LEU A 380
None
1.23A 5nd4B-2iujA:
undetectable
5nd4B-2iujA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j3t TRAFFICKING PROTEIN
PARTICLE COMPLEX
SUBUNIT 6A


(Homo sapiens)
PF04051
(TRAPP)
5 VAL B  15
LEU B  10
PHE B   7
ARG B  43
LEU B 126
None
1.24A 5nd4B-2j3tB:
undetectable
5nd4B-2j3tB:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjw UNCHARACTERIZED
PROTEIN YHL002W
VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 27


(Saccharomyces
cerevisiae)
no annotation 5 GLU V 366
LEU H 359
ALA H 362
SER H 365
LEU V 364
None
1.19A 5nd4B-2pjwV:
undetectable
5nd4B-2pjwV:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wto ORF131 PROTEIN

(Cupriavidus
metallidurans)
PF16986
(CzcE)
5 VAL A  80
ASP A  81
HIS A  24
ALA A  25
PRO A  87
CL  A1109 (-4.1A)
None
CL  A1109 (-4.5A)
None
CL  A1111 ( 4.4A)
1.27A 5nd4B-2wtoA:
undetectable
5nd4B-2wtoA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3aq1 THERMOSOME SUBUNIT

(Methanococcoides
burtonii)
PF00118
(Cpn60_TCP1)
5 VAL B 435
GLU B 434
LEU B  95
ALA B 432
LEU B 407
None
1.28A 5nd4B-3aq1B:
undetectable
5nd4B-3aq1B:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c0k UPF0064 PROTEIN YCCW

(Escherichia
coli)
PF10672
(Methyltrans_SAM)
5 GLU A 165
LEU A 140
ALA A 133
ARG A 156
ARG A  64
None
1.26A 5nd4B-3c0kA:
undetectable
5nd4B-3c0kA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dci ARYLESTERASE

(Agrobacterium
fabrum)
PF13472
(Lipase_GDSL_2)
5 VAL A  72
GLU A  71
LEU A  48
ALA A  69
LEU A 110
None
1.28A 5nd4B-3dciA:
4.9
5nd4B-3dciA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eag UDP-N-ACETYLMURAMATE
:L-ALANYL-GAMMA-D-GL
UTAMYL-MESO-DIAMINOP
IMELATE LIGASE


(Neisseria
meningitidis)
PF01225
(Mur_ligase)
PF08245
(Mur_ligase_M)
5 VAL A 229
GLU A 250
LEU A 108
ALA A 300
ARG A 302
None
1.11A 5nd4B-3eagA:
3.0
5nd4B-3eagA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eiq PROGRAMMED CELL
DEATH PROTEIN 4


(Mus musculus)
PF02847
(MA3)
5 GLU C 217
LEU C 209
PHE C 264
ARG C 267
LEU C 223
None
1.31A 5nd4B-3eiqC:
undetectable
5nd4B-3eiqC:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fw6 CELLULASE

(uncultured
bacterium)
PF12891
(Glyco_hydro_44)
5 GLU A 399
LEU A 513
ALA A 405
ARG A 425
PRO A 429
None
1.27A 5nd4B-3fw6A:
undetectable
5nd4B-3fw6A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gf7 GLUTACONYL-COA
DECARBOXYLASE
SUBUNIT A


([Clostridium]
symbiosum)
PF01039
(Carboxyl_trans)
5 VAL A 278
ASP A 275
LEU A 207
ALA A 209
PHE A 268
None
1.26A 5nd4B-3gf7A:
2.4
5nd4B-3gf7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gyb TRANSCRIPTIONAL
REGULATORS
(LACI-FAMILY
TRANSCRIPTIONAL
REGULATORY PROTEIN)


(Corynebacterium
glutamicum)
PF13377
(Peripla_BP_3)
5 VAL A  88
ASP A  87
LEU A 300
ALA A 297
LEU A  81
None
1.16A 5nd4B-3gybA:
undetectable
5nd4B-3gybA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4j TRANSLATION
INITIATION FACTOR
IF-2


(Thermus
thermophilus)
PF00009
(GTP_EFTU)
PF04760
(IF2_N)
PF11987
(IF-2)
5 VAL A 326
GLU A 324
LEU A 329
ALA A 332
ARG A 339
None
1.24A 5nd4B-3j4jA:
3.2
5nd4B-3j4jA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k70 EXODEOXYRIBONUCLEASE
V BETA CHAIN


(Escherichia
coli)
PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C)
5 GLU B 696
SER B 723
PHE B 588
ARG B 709
LEU B 694
None
1.19A 5nd4B-3k70B:
undetectable
5nd4B-3k70B:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kb3 PROTEIN PHOSPHATASE
2C 16


(Arabidopsis
thaliana)
PF00481
(PP2C)
5 VAL B 330
LEU B 427
ALA B 349
SER B 361
LEU B 434
None
1.31A 5nd4B-3kb3B:
undetectable
5nd4B-3kb3B:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mkw PROTEIN SOPB

(Escherichia
coli)
no annotation 5 HIS B 243
LEU B 242
ALA B 239
PRO B 203
LEU B 202
None
None
None
SO4  B 835 ( 4.5A)
None
1.17A 5nd4B-3mkwB:
undetectable
5nd4B-3mkwB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mky PROTEIN SOPB

(Escherichia
coli)
no annotation 5 HIS B 243
LEU B 242
ALA B 239
PRO B 203
LEU B 202
None
None
None
SO4  B 324 (-3.8A)
SO4  B 835 (-4.5A)
1.20A 5nd4B-3mkyB:
undetectable
5nd4B-3mkyB:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9o PUTATIVE
UNCHARACTERIZED
PROTEIN


(Caenorhabditis
elegans)
PF02373
(JmjC)
5 ASP A 374
LEU A 484
ALA A 485
PHE A 422
LEU A 403
None
1.23A 5nd4B-3n9oA:
undetectable
5nd4B-3n9oA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ


(Chlamydia
pneumoniae)
PF00497
(SBP_bac_3)
5 GLU A 189
HIS A 131
LEU A 134
PRO A 187
LEU A 186
None
1.27A 5nd4B-3qaxA:
undetectable
5nd4B-3qaxA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qvf FOMA PROTEIN

(Streptomyces
wedmorensis)
PF00696
(AA_kinase)
5 VAL A  95
ASP A  96
LEU A  39
PRO A 130
LEU A 124
None
1.30A 5nd4B-3qvfA:
undetectable
5nd4B-3qvfA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3shw TIGHT JUNCTION
PROTEIN ZO-1


(Homo sapiens)
PF00595
(PDZ)
PF00625
(Guanylate_kin)
PF07653
(SH3_2)
5 VAL A 450
ALA A 456
SER A 454
PHE A 427
LEU A 487
None
1.24A 5nd4B-3shwA:
2.7
5nd4B-3shwA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uan HEPARAN SULFATE
GLUCOSAMINE
3-O-SULFOTRANSFERASE
1


(Mus musculus)
PF00685
(Sulfotransfer_1)
5 VAL A 235
GLU A 236
PHE A 250
ARG A  72
LEU A  80
None
None
None
BDP  A   2 (-3.6A)
None
1.06A 5nd4B-3uanA:
undetectable
5nd4B-3uanA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujk PROTEIN PHOSPHATASE
2C 77


(Arabidopsis
thaliana)
PF00481
(PP2C)
5 VAL A 235
LEU A 332
ALA A 254
SER A 266
LEU A 339
None
1.30A 5nd4B-3ujkA:
undetectable
5nd4B-3ujkA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v78 PROBABLE
TRANSCRIPTIONAL
REGULATORY PROTEIN
(PROBABLY
DEOR-FAMILY)


(Mycobacterium
tuberculosis)
PF00440
(TetR_N)
5 ASP A 172
GLU A 173
LEU A 181
ALA A 177
PHE A 154
None
1.25A 5nd4B-3v78A:
undetectable
5nd4B-3v78A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zzu ELONGATION FACTOR G

(Staphylococcus
aureus)
PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF03144
(GTP_EFTU_D2)
PF03764
(EFG_IV)
PF14492
(EFG_II)
5 VAL A 148
HIS A 152
ALA A 159
PHE A 253
LEU A 214
None
1.32A 5nd4B-3zzuA:
3.8
5nd4B-3zzuA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ay7 METHYLCOBALAMIN:
COENZYME M
METHYLTRANSFERASE


(Methanosarcina
mazei)
PF01208
(URO-D)
5 ASP A 173
GLU A 176
LEU A 158
ALA A 178
ARG A 225
None
1.31A 5nd4B-4ay7A:
3.7
5nd4B-4ay7A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b43 TRANSLATION
INITIATION FACTOR
IF-2


(Thermus
thermophilus)
PF00009
(GTP_EFTU)
PF04760
(IF2_N)
5 VAL A 326
GLU A 324
LEU A 329
ALA A 332
ARG A 339
None
MG  A1361 (-4.1A)
None
None
MG  A1361 (-3.1A)
1.27A 5nd4B-4b43A:
2.9
5nd4B-4b43A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bv6 APOPTOSIS-INDUCING
FACTOR 1,
MITOCHONDRIAL


(Homo sapiens)
PF07992
(Pyr_redox_2)
PF14721
(AIF_C)
5 VAL A 356
LEU A 319
ALA A 316
SER A 313
LEU A 333
None
1.26A 5nd4B-4bv6A:
undetectable
5nd4B-4bv6A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c30 DNA HELICASE II

(Deinococcus
radiodurans)
PF00580
(UvrD-helicase)
PF13361
(UvrD_C)
5 GLU A 523
LEU A 487
ALA A 521
PHE A 538
ARG A 392
None
1.10A 5nd4B-4c30A:
2.1
5nd4B-4c30A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d4z DEOXYHYPUSINE
HYDROXYLASE


(Homo sapiens)
PF13646
(HEAT_2)
5 ASP A 167
GLU A 168
LEU A 194
ARG A 177
LEU A 172
None
1.33A 5nd4B-4d4zA:
undetectable
5nd4B-4d4zA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d53 BB0689

(Borreliella
burgdorferi)
PF00188
(CAP)
5 GLU A  81
LEU A 119
ALA A  47
ARG A  68
LEU A  60
None
1.30A 5nd4B-4d53A:
undetectable
5nd4B-4d53A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lix ENT-COPALYL
DIPHOSPHATE
SYNTHASE,
CHLOROPLASTIC


(Arabidopsis
thaliana)
PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C)
5 VAL A 228
LEU A 217
PHE A 214
ARG A 163
LEU A 198
None
1.21A 5nd4B-4lixA:
undetectable
5nd4B-4lixA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ntl LIPOPROTEIN, YAEC
FAMILY


(Enterococcus
faecalis)
PF03180
(Lipoprotein_9)
5 ASP A 221
GLU A 220
LEU A 157
ALA A 147
ARG A 144
None
1.25A 5nd4B-4ntlA:
undetectable
5nd4B-4ntlA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3s DNA POLYMERASE ETA

(Homo sapiens)
PF00817
(IMS)
PF11799
(IMS_C)
5 VAL A 197
GLU A 199
LEU A 237
ALA A 194
ARG A 128
None
1.30A 5nd4B-4o3sA:
undetectable
5nd4B-4o3sA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oic PROBABLE PROTEIN
PHOSPHATASE 2C 6


(Oryza sativa)
PF00481
(PP2C)
5 VAL B 284
LEU B 381
ALA B 303
SER B 315
LEU B 388
None
1.29A 5nd4B-4oicB:
undetectable
5nd4B-4oicB:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfs COBYRINIC ACID
A,C-DIAMIDE SYNTHASE


(Mycolicibacterium
smegmatis)
PF13614
(AAA_31)
6 VAL A  76
ASP A  75
GLU A  70
LEU A  82
ALA A  81
LEU A  98
None
1.38A 5nd4B-4pfsA:
3.7
5nd4B-4pfsA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2e PHOSPHATIDATE
CYTIDYLYLTRANSFERASE


(Thermotoga
maritima)
PF01148
(CTP_transf_1)
5 VAL A 156
LEU A 272
ALA A 275
PRO A 143
LEU A 142
None
1.22A 5nd4B-4q2eA:
undetectable
5nd4B-4q2eA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2e PHOSPHATIDATE
CYTIDYLYLTRANSFERASE


(Thermotoga
maritima)
PF01148
(CTP_transf_1)
5 VAL A 156
LEU A 272
ALA A 275
SER A 278
LEU A 142
None
1.24A 5nd4B-4q2eA:
undetectable
5nd4B-4q2eA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q2q TIGHT JUNCTION
PROTEIN ZO-1


(Homo sapiens)
PF00595
(PDZ)
5 VAL A 449
ALA A 455
SER A 453
PHE A 426
LEU A 486
None
1.27A 5nd4B-4q2qA:
undetectable
5nd4B-4q2qA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qt8 MACROPHAGE-STIMULATI
NG PROTEIN RECEPTOR


(Homo sapiens)
no annotation 5 GLU B 475
LEU B 451
ALA B 462
ARG B 470
LEU B 483
None
None
None
NAG  B 701 (-3.7A)
None
1.26A 5nd4B-4qt8B:
undetectable
5nd4B-4qt8B:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u65 PUTATIVE CYSTINE
PROTEASE


(Pseudomonas
fluorescens)
PF06035
(Peptidase_C93)
5 GLU E 211
SER E 153
PHE E 144
ARG E 232
LEU E 237
None
1.33A 5nd4B-4u65E:
undetectable
5nd4B-4u65E:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wer DIACYLGLYCEROL
KINASE CATALYTIC
DOMAIN PROTEIN


(Enterococcus
faecalis)
PF00781
(DAGK_cat)
5 ASP A  33
LEU A   6
ALA A   4
PHE A  62
LEU A 116
None
1.09A 5nd4B-4werA:
undetectable
5nd4B-4werA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y9t ABC TRANSPORTER,
SOLUTE BINDING
PROTEIN


(Agrobacterium
vitis)
PF13407
(Peripla_BP_4)
5 LEU A  49
ALA A  48
PHE A  52
PRO A 338
LEU A 299
None
1.26A 5nd4B-4y9tA:
4.1
5nd4B-4y9tA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a05 ALDOSE-ALDOSE
OXIDOREDUCTASE


(Caulobacter
vibrioides)
PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C)
5 VAL A  74
ASP A  75
LEU A  37
ALA A  10
LEU A 297
None
1.29A 5nd4B-5a05A:
3.0
5nd4B-5a05A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aga DNA POLYMERASE THETA

(Homo sapiens)
PF00270
(DEAD)
PF00271
(Helicase_C)
5 ASP A 216
HIS A 219
LEU A 512
ALA A 266
SER A 114
MG  A1895 (-3.2A)
None
None
None
None
1.28A 5nd4B-5agaA:
undetectable
5nd4B-5agaA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c92 KELCH
DOMAIN-CONTAINING
PROTEIN


(Colletotrichum
graminicola)
PF01344
(Kelch_1)
PF09118
(DUF1929)
5 LEU A 463
ALA A 475
PHE A 464
ARG A 417
LEU A 340
None
1.08A 5nd4B-5c92A:
undetectable
5nd4B-5c92A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cbk SHHTL5

(Striga
hermonthica)
PF12697
(Abhydrolase_6)
5 VAL A 205
ALA A 102
SER A 105
ARG A 123
LEU A  70
None
1.26A 5nd4B-5cbkA:
3.8
5nd4B-5cbkA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cml OSMC FAMILY PROTEIN

(Rhodothermus
marinus)
PF12146
(Hydrolase_4)
5 VAL A 179
GLU A 175
LEU A 116
ALA A 117
ARG A  89
None
1.24A 5nd4B-5cmlA:
4.5
5nd4B-5cmlA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e84 78 KDA
GLUCOSE-REGULATED
PROTEIN


(Homo sapiens)
PF00012
(HSP70)
5 VAL A 345
ASP A 348
SER A 233
PRO A 421
LEU A 422
None
1.25A 5nd4B-5e84A:
undetectable
5nd4B-5e84A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ed7 TEGUMENT PROTEIN
UL21


(Human
alphaherpesvirus
1)
PF03252
(Herpes_UL21)
5 VAL A 495
ASP A 494
ALA A 403
PHE A 462
LEU A 488
None
1.19A 5nd4B-5ed7A:
undetectable
5nd4B-5ed7A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h2t TREHALOSE SYNTHASE

(Thermomonospora
curvata)
no annotation 5 ASP A 103
GLU A 100
LEU A  57
ARG A  48
LEU A  47
None
1.02A 5nd4B-5h2tA:
undetectable
5nd4B-5h2tA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jqe SUGAR ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN,CASPASE-8
CHIMERA


(Escherichia
coli)
PF01335
(DED)
PF13416
(SBP_bac_8)
5 ASP A1015
LEU A1042
ALA A1041
PHE A1045
LEU A1066
None
0.95A 5nd4B-5jqeA:
undetectable
5nd4B-5jqeA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m73 SIGNAL RECOGNITION
PARTICLE 19 KDA
PROTEIN


(Homo sapiens)
PF01922
(SRP19)
5 VAL B  52
GLU B  48
ALA B 108
ARG B  81
PRO B  44
None
None
None
G  A 198 ( 3.2A)
None
1.23A 5nd4B-5m73B:
undetectable
5nd4B-5m73B:
14.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 ASP A  26
GLU A  27
HIS A 227
ARG A 317
PRO A 357
None
0.95A 5nd4B-5mjsA:
55.6
5nd4B-5mjsA:
58.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 ASP A  26
GLU A  27
HIS A 227
LEU A 228
PRO A 357
None
0.83A 5nd4B-5mjsA:
55.6
5nd4B-5mjsA:
58.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 ASP A  26
GLU A  27
LEU A 228
ALA A 231
PRO A 357
None
0.99A 5nd4B-5mjsA:
55.6
5nd4B-5mjsA:
58.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 ASP A  26
HIS A 227
ARG A 317
PRO A 357
LEU A 360
None
0.94A 5nd4B-5mjsA:
55.6
5nd4B-5mjsA:
58.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 ASP A  26
HIS A 227
LEU A 228
PRO A 357
LEU A 360
None
0.78A 5nd4B-5mjsA:
55.6
5nd4B-5mjsA:
58.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe)
no annotation 5 ASP A  26
LEU A 228
ALA A 231
PRO A 357
LEU A 360
None
0.93A 5nd4B-5mjsA:
55.6
5nd4B-5mjsA:
58.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 6 VAL B  23
ALA B 233
SER B 236
PHE B 272
PRO B 360
LEU B 371
None
0.91A 5nd4B-5n5nB:
56.3
5nd4B-5n5nB:
97.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 7 VAL B  23
GLU B  27
ALA B 233
PHE B 272
ARG B 320
PRO B 360
LEU B 371
None
1.04A 5nd4B-5n5nB:
56.3
5nd4B-5n5nB:
97.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 7 VAL B  23
GLU B  27
HIS B 229
ALA B 233
PHE B 272
ARG B 320
PRO B 360
None
0.96A 5nd4B-5n5nB:
56.3
5nd4B-5n5nB:
97.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 6 VAL B  23
HIS B 229
ALA B 233
SER B 236
PHE B 272
PRO B 360
None
0.80A 5nd4B-5n5nB:
56.3
5nd4B-5n5nB:
97.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 7 VAL B  23
HIS B 229
LEU B 230
ALA B 233
PHE B 272
ARG B 320
PRO B 360
None
0.85A 5nd4B-5n5nB:
56.3
5nd4B-5n5nB:
97.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5n5n TUBULIN BETA CHAIN

(Homo sapiens)
no annotation 7 VAL B  23
LEU B 230
ALA B 233
PHE B 272
ARG B 320
PRO B 360
LEU B 371
None
0.98A 5nd4B-5n5nB:
56.3
5nd4B-5n5nB:
97.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ncc FATTY ACID
PHOTODECARBOXYLASE


(Chlorella
variabilis)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
5 GLU A 114
LEU A  98
ALA A  95
ARG A 109
LEU A 113
FAD  A 701 (-2.6A)
None
None
None
None
1.18A 5nd4B-5nccA:
undetectable
5nd4B-5nccA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sv2 RIBONUCLEASE VAPC21

(Mycobacterium
tuberculosis)
PF01850
(PIN)
5 ASP A  40
GLU A  42
LEU A  24
ALA A  12
ARG A   4
None
1.30A 5nd4B-5sv2A:
undetectable
5nd4B-5sv2A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u6s UDP-GLYCOSYLTRANSFER
ASE 74F2


(Arabidopsis
thaliana)
PF00201
(UDPGT)
5 VAL A   8
LEU A  38
ALA A  10
PHE A  22
ARG A  28
None
1.30A 5nd4B-5u6sA:
4.8
5nd4B-5u6sA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v57 SMOOTHENED
HOMOLOG,FLAVODOXIN,S
MOOTHENED HOMOLOG


(Desulfovibrio
vulgaris;
Homo sapiens)
PF00258
(Flavodoxin_1)
PF01392
(Fz)
PF01534
(Frizzled)
5 VAL A 210
ASP A 209
GLU A 211
ALA A 115
PRO A 153
None
1.30A 5nd4B-5v57A:
4.4
5nd4B-5v57A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vfa RESPONSE REGULATOR

(Streptococcus
pneumoniae)
no annotation 5 VAL A  32
ASP A  30
LEU A  56
ALA A  38
PHE A  64
None
1.31A 5nd4B-5vfaA:
4.3
5nd4B-5vfaA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5voc ENVELOPE
GLYCOPROTEIN H


(Human
betaherpesvirus
5)
PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C)
5 VAL A 490
GLU A 486
ALA A 447
ARG A 441
LEU A 440
None
1.11A 5nd4B-5vocA:
undetectable
5nd4B-5vocA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
6 VAL B  23
ASP B  26
GLU B  27
LEU B 228
ARG B 318
LEU B 361
TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 (-3.6A)
None
None
TA1  B 502 (-3.7A)
1.11A 5nd4B-5w3jB:
56.0
5nd4B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
6 VAL B  23
ASP B  26
LEU B 228
ARG B 318
PRO B 358
LEU B 361
TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
None
None
None
TA1  B 502 (-3.7A)
1.10A 5nd4B-5w3jB:
56.0
5nd4B-5w3jB:
77.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5w3j TUBULIN BETA CHAIN

(Saccharomyces
cerevisiae)
PF00091
(Tubulin)
PF03953
(Tubulin_C)
6 VAL B  23
ASP B  26
SER B 234
ARG B 318
PRO B 358
LEU B 361
TA1  B 502 (-3.9A)
TA1  B 502 (-4.1A)
TA1  B 502 ( 4.9A)
None
None
TA1  B 502 (-3.7A)
0.95A 5nd4B-5w3jB:
56.0
5nd4B-5w3jB:
77.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wbl REGULATORY-ASSOCIATE
D PROTEIN OF TOR 1


(Arabidopsis
thaliana)
no annotation 5 VAL A1133
ASP A1134
ALA A1092
SER A1076
LEU A1034
None
1.29A 5nd4B-5wblA:
undetectable
5nd4B-5wblA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wql TAIL-SPECIFIC
PROTEASE


(Escherichia
coli)
no annotation 5 VAL C 469
LEU C 392
ALA C 458
ARG C 448
ARG C 513
None
1.12A 5nd4B-5wqlC:
undetectable
5nd4B-5wqlC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wyb PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE


(Pseudomonas
aeruginosa)
no annotation 5 VAL B 195
ASP B 196
GLU B 137
LEU B 206
ALA B 203
None
None
None
None
ACT  B 302 ( 4.4A)
1.31A 5nd4B-5wybB:
undetectable
5nd4B-5wybB:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xdr PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE DHX15


(Homo sapiens)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind)
5 VAL A 701
LEU A 693
ARG A 748
PRO A 731
LEU A 727
None
1.09A 5nd4B-5xdrA:
undetectable
5nd4B-5xdrA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1


(Saccharomyces
cerevisiae)
no annotation 5 ASP A  62
LEU A 117
ALA A  83
PHE A 109
ARG D  74
None
1.10A 5nd4B-6eojA:
undetectable
5nd4B-6eojA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eq8 PERIPLASMIC
ALPHA-GALACTOSIDE-BI
NDING PROTEIN


(Agrobacterium
tumefaciens)
no annotation 5 ASP D 380
GLU D 381
LEU D 389
ALA D 385
ARG D 507
None
1.03A 5nd4B-6eq8D:
undetectable
5nd4B-6eq8D:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6req PROTEIN
(METHYLMALONYL-COA
MUTASE)


(Propionibacterium
freudenreichii)
PF01642
(MM_CoA_mutase)
5 VAL B 463
GLU B 498
ARG B 472
ARG B 492
LEU B 367
None
1.32A 5nd4B-6reqB:
4.7
5nd4B-6reqB:
22.68