SIMILAR PATTERNS OF AMINO ACIDS FOR 5ND4_B_TA1B601_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k1b | B-CELL LYMPHOMA3-ENCODED PROTEIN (Homo sapiens) |
PF00023(Ank)PF12796(Ank_2) | 5 | VAL A 242GLU A 245LEU A 272ALA A 275LEU A 281 | None | 1.14A | 5nd4B-1k1bA:undetectable | 5nd4B-1k1bA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5d | P450 EPOXIDASE (Sorangiumcellulosum) |
PF00067(p450) | 5 | VAL A 191ASP A 192GLU A 193LEU A 183ALA A 182 | NoneNoneNoneEPB A 450 (-4.3A)None | 1.05A | 5nd4B-1q5dA:undetectable | 5nd4B-1q5dA:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s2j | PEPTIDOGLYCANRECOGNITION PROTEINSA CG11709-PA (Drosophilamelanogaster) |
PF01510(Amidase_2) | 5 | ASP A 122LEU A 132ALA A 128PRO A 120LEU A 163 | None | 1.22A | 5nd4B-1s2jA:undetectable | 5nd4B-1s2jA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sxr | PEPTIDOGLYCANRECOGNITION PROTEINSA CG11709-PA (Drosophilamelanogaster) |
PF01510(Amidase_2) | 5 | ASP A 122LEU A 132ALA A 128PRO A 120LEU A 163 | None | 1.23A | 5nd4B-1sxrA:undetectable | 5nd4B-1sxrA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u2l | PEROXIDASE/CATALASEHPI (Escherichiacoli) |
PF00141(peroxidase) | 5 | VAL A 512GLU A 514ALA A 509ARG A 498LEU A 492 | None | 1.20A | 5nd4B-1u2lA:undetectable | 5nd4B-1u2lA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uz5 | 402AA LONGHYPOTHETICALMOLYBDOPTERINBIOSYNTHESIS MOEAPROTEIN (Pyrococcushorikoshii) |
PF00994(MoCF_biosynth)PF03453(MoeA_N)PF03454(MoeA_C) | 5 | VAL A 394GLU A 395LEU A 358ALA A 334LEU A 398 | None | 1.09A | 5nd4B-1uz5A:undetectable | 5nd4B-1uz5A:24.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w9x | ALPHA AMYLASE (Bacillushalmapalus) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 5 | ASP A 308LEU A 297ALA A 300SER A 303PHE A 348 | None | 1.24A | 5nd4B-1w9xA:3.0 | 5nd4B-1w9xA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdt | ELONGATION FACTOR GHOMOLOG (Thermusthermophilus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03764(EFG_IV)PF14492(EFG_II) | 5 | GLU A 408HIS A 432LEU A 433ALA A 436LEU A 406 | None | 1.08A | 5nd4B-1wdtA:undetectable | 5nd4B-1wdtA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdw | TRYPTOPHAN SYNTHASEBETA CHAIN 1 (Pyrococcusfuriosus) |
PF00291(PALP) | 5 | VAL B 304HIS B 308LEU B 311SER B 279PRO B 193 | None | 1.32A | 5nd4B-1wdwB:undetectable | 5nd4B-1wdwB:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wyt | GLYCINEDEHYDROGENASE(DECARBOXYLATING)SUBUNIT 1 (Thermusthermophilus) |
PF02347(GDC-P) | 5 | ASP A 385LEU A 380ALA A 413PHE A 415LEU A 393 | None | 1.24A | 5nd4B-1wytA:2.1 | 5nd4B-1wytA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x1b | CRTF-RELATED PROTEIN (Chlorobaculumtepidum) |
PF00891(Methyltransf_2) | 5 | VAL A 208GLU A 210LEU A 201ALA A 204ARG A 140 | NoneNoneSAH A4261 (-4.0A)NoneNone | 1.27A | 5nd4B-1x1bA:undetectable | 5nd4B-1x1bA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yts | YERSINIA PROTEINTYROSINE PHOSPHATASE (Yersiniaenterocolitica) |
PF00102(Y_phosphatase) | 5 | VAL A 372ASP A 373LEU A 282ALA A 283ARG A 398 | None | 1.30A | 5nd4B-1ytsA:undetectable | 5nd4B-1ytsA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zye | THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE (Bos taurus) |
PF00578(AhpC-TSA)PF10417(1-cysPrx_C) | 5 | VAL A 73ASP A 74LEU A 115ALA A 121SER A 108 | None | 1.31A | 5nd4B-1zyeA:undetectable | 5nd4B-1zyeA:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c6r | DNA-BINDING STRESSRESPONSE PROTEIN,DPS FAMILY (Deinococcusradiodurans) |
PF00210(Ferritin) | 5 | GLU A 58LEU A 64ALA A 61ARG A 113LEU A 56 | None | 1.26A | 5nd4B-2c6rA:undetectable | 5nd4B-2c6rA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2die | AMYLASE (Bacillus sp.(in: Bacteria)) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 5 | ASP A 308LEU A 297ALA A 300SER A 303PHE A 348 | None | 1.19A | 5nd4B-2dieA:3.2 | 5nd4B-2dieA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eid | GALACTOSE OXIDASE (Fusariumgraminearum) |
PF00754(F5_F8_type_C)PF01344(Kelch_1)PF09118(DUF1929) | 5 | LEU A 620ALA A 632PHE A 621ARG A 575LEU A 501 | None | 1.03A | 5nd4B-2eidA:undetectable | 5nd4B-2eidA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ghp | U4/U6SNRNA-ASSOCIATEDSPLICING FACTORPRP24 (Saccharomycescerevisiae) |
PF00076(RRM_1) | 5 | VAL A 165ASP A 164LEU A 178ARG A 268ARG A 134 | None | 1.20A | 5nd4B-2ghpA:undetectable | 5nd4B-2ghpA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gz4 | HYPOTHETICAL PROTEINATU1052 (Agrobacteriumfabrum) |
no annotation | 5 | ASP A 77GLU A 78HIS A 119ALA A 128ARG A 135 | None | 1.15A | 5nd4B-2gz4A:undetectable | 5nd4B-2gz4A:19.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | VAL A 480GLU A 463HIS A 400ALA A 461LEU A 380 | None | 1.16A | 5nd4B-2iujA:undetectable | 5nd4B-2iujA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iuj | LIPOXYGENASE L-5 (Glycine max) |
PF00305(Lipoxygenase)PF01477(PLAT) | 5 | VAL A 480GLU A 463LEU A 460ALA A 461LEU A 380 | None | 1.23A | 5nd4B-2iujA:undetectable | 5nd4B-2iujA:19.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3t | TRAFFICKING PROTEINPARTICLE COMPLEXSUBUNIT 6A (Homo sapiens) |
PF04051(TRAPP) | 5 | VAL B 15LEU B 10PHE B 7ARG B 43LEU B 126 | None | 1.24A | 5nd4B-2j3tB:undetectable | 5nd4B-2j3tB:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pjw | UNCHARACTERIZEDPROTEIN YHL002WVACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 27 (Saccharomycescerevisiae) |
no annotation | 5 | GLU V 366LEU H 359ALA H 362SER H 365LEU V 364 | None | 1.19A | 5nd4B-2pjwV:undetectable | 5nd4B-2pjwV:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wto | ORF131 PROTEIN (Cupriavidusmetallidurans) |
PF16986(CzcE) | 5 | VAL A 80ASP A 81HIS A 24ALA A 25PRO A 87 | CL A1109 (-4.1A)None CL A1109 (-4.5A)None CL A1111 ( 4.4A) | 1.27A | 5nd4B-2wtoA:undetectable | 5nd4B-2wtoA:12.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aq1 | THERMOSOME SUBUNIT (Methanococcoidesburtonii) |
PF00118(Cpn60_TCP1) | 5 | VAL B 435GLU B 434LEU B 95ALA B 432LEU B 407 | None | 1.28A | 5nd4B-3aq1B:undetectable | 5nd4B-3aq1B:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c0k | UPF0064 PROTEIN YCCW (Escherichiacoli) |
PF10672(Methyltrans_SAM) | 5 | GLU A 165LEU A 140ALA A 133ARG A 156ARG A 64 | None | 1.26A | 5nd4B-3c0kA:undetectable | 5nd4B-3c0kA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dci | ARYLESTERASE (Agrobacteriumfabrum) |
PF13472(Lipase_GDSL_2) | 5 | VAL A 72GLU A 71LEU A 48ALA A 69LEU A 110 | None | 1.28A | 5nd4B-3dciA:4.9 | 5nd4B-3dciA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eag | UDP-N-ACETYLMURAMATE:L-ALANYL-GAMMA-D-GLUTAMYL-MESO-DIAMINOPIMELATE LIGASE (Neisseriameningitidis) |
PF01225(Mur_ligase)PF08245(Mur_ligase_M) | 5 | VAL A 229GLU A 250LEU A 108ALA A 300ARG A 302 | None | 1.11A | 5nd4B-3eagA:3.0 | 5nd4B-3eagA:22.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eiq | PROGRAMMED CELLDEATH PROTEIN 4 (Mus musculus) |
PF02847(MA3) | 5 | GLU C 217LEU C 209PHE C 264ARG C 267LEU C 223 | None | 1.31A | 5nd4B-3eiqC:undetectable | 5nd4B-3eiqC:21.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw6 | CELLULASE (unculturedbacterium) |
PF12891(Glyco_hydro_44) | 5 | GLU A 399LEU A 513ALA A 405ARG A 425PRO A 429 | None | 1.27A | 5nd4B-3fw6A:undetectable | 5nd4B-3fw6A:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gf7 | GLUTACONYL-COADECARBOXYLASESUBUNIT A ([Clostridium]symbiosum) |
PF01039(Carboxyl_trans) | 5 | VAL A 278ASP A 275LEU A 207ALA A 209PHE A 268 | None | 1.26A | 5nd4B-3gf7A:2.4 | 5nd4B-3gf7A:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gyb | TRANSCRIPTIONALREGULATORS(LACI-FAMILYTRANSCRIPTIONALREGULATORY PROTEIN) (Corynebacteriumglutamicum) |
PF13377(Peripla_BP_3) | 5 | VAL A 88ASP A 87LEU A 300ALA A 297LEU A 81 | None | 1.16A | 5nd4B-3gybA:undetectable | 5nd4B-3gybA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j4j | TRANSLATIONINITIATION FACTORIF-2 (Thermusthermophilus) |
PF00009(GTP_EFTU)PF04760(IF2_N)PF11987(IF-2) | 5 | VAL A 326GLU A 324LEU A 329ALA A 332ARG A 339 | None | 1.24A | 5nd4B-3j4jA:3.2 | 5nd4B-3j4jA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k70 | EXODEOXYRIBONUCLEASEV BETA CHAIN (Escherichiacoli) |
PF00580(UvrD-helicase)PF12705(PDDEXK_1)PF13361(UvrD_C) | 5 | GLU B 696SER B 723PHE B 588ARG B 709LEU B 694 | None | 1.19A | 5nd4B-3k70B:undetectable | 5nd4B-3k70B:15.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kb3 | PROTEIN PHOSPHATASE2C 16 (Arabidopsisthaliana) |
PF00481(PP2C) | 5 | VAL B 330LEU B 427ALA B 349SER B 361LEU B 434 | None | 1.31A | 5nd4B-3kb3B:undetectable | 5nd4B-3kb3B:20.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkw | PROTEIN SOPB (Escherichiacoli) |
no annotation | 5 | HIS B 243LEU B 242ALA B 239PRO B 203LEU B 202 | NoneNoneNoneSO4 B 835 ( 4.5A)None | 1.17A | 5nd4B-3mkwB:undetectable | 5nd4B-3mkwB:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mky | PROTEIN SOPB (Escherichiacoli) |
no annotation | 5 | HIS B 243LEU B 242ALA B 239PRO B 203LEU B 202 | NoneNoneNoneSO4 B 324 (-3.8A)SO4 B 835 (-4.5A) | 1.20A | 5nd4B-3mkyB:undetectable | 5nd4B-3mkyB:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n9o | PUTATIVEUNCHARACTERIZEDPROTEIN (Caenorhabditiselegans) |
PF02373(JmjC) | 5 | ASP A 374LEU A 484ALA A 485PHE A 422LEU A 403 | None | 1.23A | 5nd4B-3n9oA:undetectable | 5nd4B-3n9oA:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qax | PROBABLE ABCTRANSPORTERARGININE-BINDINGPROTEIN ARTJ (Chlamydiapneumoniae) |
PF00497(SBP_bac_3) | 5 | GLU A 189HIS A 131LEU A 134PRO A 187LEU A 186 | None | 1.27A | 5nd4B-3qaxA:undetectable | 5nd4B-3qaxA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qvf | FOMA PROTEIN (Streptomyceswedmorensis) |
PF00696(AA_kinase) | 5 | VAL A 95ASP A 96LEU A 39PRO A 130LEU A 124 | None | 1.30A | 5nd4B-3qvfA:undetectable | 5nd4B-3qvfA:22.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3shw | TIGHT JUNCTIONPROTEIN ZO-1 (Homo sapiens) |
PF00595(PDZ)PF00625(Guanylate_kin)PF07653(SH3_2) | 5 | VAL A 450ALA A 456SER A 454PHE A 427LEU A 487 | None | 1.24A | 5nd4B-3shwA:2.7 | 5nd4B-3shwA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uan | HEPARAN SULFATEGLUCOSAMINE3-O-SULFOTRANSFERASE1 (Mus musculus) |
PF00685(Sulfotransfer_1) | 5 | VAL A 235GLU A 236PHE A 250ARG A 72LEU A 80 | NoneNoneNoneBDP A 2 (-3.6A)None | 1.06A | 5nd4B-3uanA:undetectable | 5nd4B-3uanA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ujk | PROTEIN PHOSPHATASE2C 77 (Arabidopsisthaliana) |
PF00481(PP2C) | 5 | VAL A 235LEU A 332ALA A 254SER A 266LEU A 339 | None | 1.30A | 5nd4B-3ujkA:undetectable | 5nd4B-3ujkA:21.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v78 | PROBABLETRANSCRIPTIONALREGULATORY PROTEIN(PROBABLYDEOR-FAMILY) (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | ASP A 172GLU A 173LEU A 181ALA A 177PHE A 154 | None | 1.25A | 5nd4B-3v78A:undetectable | 5nd4B-3v78A:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zzu | ELONGATION FACTOR G (Staphylococcusaureus) |
PF00009(GTP_EFTU)PF00679(EFG_C)PF03144(GTP_EFTU_D2)PF03764(EFG_IV)PF14492(EFG_II) | 5 | VAL A 148HIS A 152ALA A 159PHE A 253LEU A 214 | None | 1.32A | 5nd4B-3zzuA:3.8 | 5nd4B-3zzuA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ay7 | METHYLCOBALAMIN:COENZYME MMETHYLTRANSFERASE (Methanosarcinamazei) |
PF01208(URO-D) | 5 | ASP A 173GLU A 176LEU A 158ALA A 178ARG A 225 | None | 1.31A | 5nd4B-4ay7A:3.7 | 5nd4B-4ay7A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b43 | TRANSLATIONINITIATION FACTORIF-2 (Thermusthermophilus) |
PF00009(GTP_EFTU)PF04760(IF2_N) | 5 | VAL A 326GLU A 324LEU A 329ALA A 332ARG A 339 | None MG A1361 (-4.1A)NoneNone MG A1361 (-3.1A) | 1.27A | 5nd4B-4b43A:2.9 | 5nd4B-4b43A:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bv6 | APOPTOSIS-INDUCINGFACTOR 1,MITOCHONDRIAL (Homo sapiens) |
PF07992(Pyr_redox_2)PF14721(AIF_C) | 5 | VAL A 356LEU A 319ALA A 316SER A 313LEU A 333 | None | 1.26A | 5nd4B-4bv6A:undetectable | 5nd4B-4bv6A:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c30 | DNA HELICASE II (Deinococcusradiodurans) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 5 | GLU A 523LEU A 487ALA A 521PHE A 538ARG A 392 | None | 1.10A | 5nd4B-4c30A:2.1 | 5nd4B-4c30A:21.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d4z | DEOXYHYPUSINEHYDROXYLASE (Homo sapiens) |
PF13646(HEAT_2) | 5 | ASP A 167GLU A 168LEU A 194ARG A 177LEU A 172 | None | 1.33A | 5nd4B-4d4zA:undetectable | 5nd4B-4d4zA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d53 | BB0689 (Borreliellaburgdorferi) |
PF00188(CAP) | 5 | GLU A 81LEU A 119ALA A 47ARG A 68LEU A 60 | None | 1.30A | 5nd4B-4d53A:undetectable | 5nd4B-4d53A:15.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lix | ENT-COPALYLDIPHOSPHATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | VAL A 228LEU A 217PHE A 214ARG A 163LEU A 198 | None | 1.21A | 5nd4B-4lixA:undetectable | 5nd4B-4lixA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ntl | LIPOPROTEIN, YAECFAMILY (Enterococcusfaecalis) |
PF03180(Lipoprotein_9) | 5 | ASP A 221GLU A 220LEU A 157ALA A 147ARG A 144 | None | 1.25A | 5nd4B-4ntlA:undetectable | 5nd4B-4ntlA:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o3s | DNA POLYMERASE ETA (Homo sapiens) |
PF00817(IMS)PF11799(IMS_C) | 5 | VAL A 197GLU A 199LEU A 237ALA A 194ARG A 128 | None | 1.30A | 5nd4B-4o3sA:undetectable | 5nd4B-4o3sA:21.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oic | PROBABLE PROTEINPHOSPHATASE 2C 6 (Oryza sativa) |
PF00481(PP2C) | 5 | VAL B 284LEU B 381ALA B 303SER B 315LEU B 388 | None | 1.29A | 5nd4B-4oicB:undetectable | 5nd4B-4oicB:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pfs | COBYRINIC ACIDA,C-DIAMIDE SYNTHASE (Mycolicibacteriumsmegmatis) |
PF13614(AAA_31) | 6 | VAL A 76ASP A 75GLU A 70LEU A 82ALA A 81LEU A 98 | None | 1.38A | 5nd4B-4pfsA:3.7 | 5nd4B-4pfsA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2e | PHOSPHATIDATECYTIDYLYLTRANSFERASE (Thermotogamaritima) |
PF01148(CTP_transf_1) | 5 | VAL A 156LEU A 272ALA A 275PRO A 143LEU A 142 | None | 1.22A | 5nd4B-4q2eA:undetectable | 5nd4B-4q2eA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2e | PHOSPHATIDATECYTIDYLYLTRANSFERASE (Thermotogamaritima) |
PF01148(CTP_transf_1) | 5 | VAL A 156LEU A 272ALA A 275SER A 278LEU A 142 | None | 1.24A | 5nd4B-4q2eA:undetectable | 5nd4B-4q2eA:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q2q | TIGHT JUNCTIONPROTEIN ZO-1 (Homo sapiens) |
PF00595(PDZ) | 5 | VAL A 449ALA A 455SER A 453PHE A 426LEU A 486 | None | 1.27A | 5nd4B-4q2qA:undetectable | 5nd4B-4q2qA:14.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qt8 | MACROPHAGE-STIMULATING PROTEIN RECEPTOR (Homo sapiens) |
no annotation | 5 | GLU B 475LEU B 451ALA B 462ARG B 470LEU B 483 | NoneNoneNoneNAG B 701 (-3.7A)None | 1.26A | 5nd4B-4qt8B:undetectable | 5nd4B-4qt8B:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u65 | PUTATIVE CYSTINEPROTEASE (Pseudomonasfluorescens) |
PF06035(Peptidase_C93) | 5 | GLU E 211SER E 153PHE E 144ARG E 232LEU E 237 | None | 1.33A | 5nd4B-4u65E:undetectable | 5nd4B-4u65E:18.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wer | DIACYLGLYCEROLKINASE CATALYTICDOMAIN PROTEIN (Enterococcusfaecalis) |
PF00781(DAGK_cat) | 5 | ASP A 33LEU A 6ALA A 4PHE A 62LEU A 116 | None | 1.09A | 5nd4B-4werA:undetectable | 5nd4B-4werA:22.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y9t | ABC TRANSPORTER,SOLUTE BINDINGPROTEIN (Agrobacteriumvitis) |
PF13407(Peripla_BP_4) | 5 | LEU A 49ALA A 48PHE A 52PRO A 338LEU A 299 | None | 1.26A | 5nd4B-4y9tA:4.1 | 5nd4B-4y9tA:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a05 | ALDOSE-ALDOSEOXIDOREDUCTASE (Caulobactervibrioides) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 5 | VAL A 74ASP A 75LEU A 37ALA A 10LEU A 297 | None | 1.29A | 5nd4B-5a05A:3.0 | 5nd4B-5a05A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aga | DNA POLYMERASE THETA (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 5 | ASP A 216HIS A 219LEU A 512ALA A 266SER A 114 | MG A1895 (-3.2A)NoneNoneNoneNone | 1.28A | 5nd4B-5agaA:undetectable | 5nd4B-5agaA:19.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c92 | KELCHDOMAIN-CONTAININGPROTEIN (Colletotrichumgraminicola) |
PF01344(Kelch_1)PF09118(DUF1929) | 5 | LEU A 463ALA A 475PHE A 464ARG A 417LEU A 340 | None | 1.08A | 5nd4B-5c92A:undetectable | 5nd4B-5c92A:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cbk | SHHTL5 (Strigahermonthica) |
PF12697(Abhydrolase_6) | 5 | VAL A 205ALA A 102SER A 105ARG A 123LEU A 70 | None | 1.26A | 5nd4B-5cbkA:3.8 | 5nd4B-5cbkA:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cml | OSMC FAMILY PROTEIN (Rhodothermusmarinus) |
PF12146(Hydrolase_4) | 5 | VAL A 179GLU A 175LEU A 116ALA A 117ARG A 89 | None | 1.24A | 5nd4B-5cmlA:4.5 | 5nd4B-5cmlA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e84 | 78 KDAGLUCOSE-REGULATEDPROTEIN (Homo sapiens) |
PF00012(HSP70) | 5 | VAL A 345ASP A 348SER A 233PRO A 421LEU A 422 | None | 1.25A | 5nd4B-5e84A:undetectable | 5nd4B-5e84A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ed7 | TEGUMENT PROTEINUL21 (Humanalphaherpesvirus1) |
PF03252(Herpes_UL21) | 5 | VAL A 495ASP A 494ALA A 403PHE A 462LEU A 488 | None | 1.19A | 5nd4B-5ed7A:undetectable | 5nd4B-5ed7A:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h2t | TREHALOSE SYNTHASE (Thermomonosporacurvata) |
no annotation | 5 | ASP A 103GLU A 100LEU A 57ARG A 48LEU A 47 | None | 1.02A | 5nd4B-5h2tA:undetectable | 5nd4B-5h2tA:19.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jqe | SUGAR ABCTRANSPORTERSUBSTRATE-BINDINGPROTEIN,CASPASE-8CHIMERA (Escherichiacoli) |
PF01335(DED)PF13416(SBP_bac_8) | 5 | ASP A1015LEU A1042ALA A1041PHE A1045LEU A1066 | None | 0.95A | 5nd4B-5jqeA:undetectable | 5nd4B-5jqeA:20.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m73 | SIGNAL RECOGNITIONPARTICLE 19 KDAPROTEIN (Homo sapiens) |
PF01922(SRP19) | 5 | VAL B 52GLU B 48ALA B 108ARG B 81PRO B 44 | NoneNoneNone G A 198 ( 3.2A)None | 1.23A | 5nd4B-5m73B:undetectable | 5nd4B-5m73B:14.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | ASP A 26GLU A 27HIS A 227ARG A 317PRO A 357 | None | 0.95A | 5nd4B-5mjsA:55.6 | 5nd4B-5mjsA:58.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | ASP A 26GLU A 27HIS A 227LEU A 228PRO A 357 | None | 0.83A | 5nd4B-5mjsA:55.6 | 5nd4B-5mjsA:58.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | ASP A 26GLU A 27LEU A 228ALA A 231PRO A 357 | None | 0.99A | 5nd4B-5mjsA:55.6 | 5nd4B-5mjsA:58.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | ASP A 26HIS A 227ARG A 317PRO A 357LEU A 360 | None | 0.94A | 5nd4B-5mjsA:55.6 | 5nd4B-5mjsA:58.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | ASP A 26HIS A 227LEU A 228PRO A 357LEU A 360 | None | 0.78A | 5nd4B-5mjsA:55.6 | 5nd4B-5mjsA:58.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5mjs | TUBULIN BETA CHAIN (Schizosaccharomycespombe) |
no annotation | 5 | ASP A 26LEU A 228ALA A 231PRO A 357LEU A 360 | None | 0.93A | 5nd4B-5mjsA:55.6 | 5nd4B-5mjsA:58.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 6 | VAL B 23ALA B 233SER B 236PHE B 272PRO B 360LEU B 371 | None | 0.91A | 5nd4B-5n5nB:56.3 | 5nd4B-5n5nB:97.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 7 | VAL B 23GLU B 27ALA B 233PHE B 272ARG B 320PRO B 360LEU B 371 | None | 1.04A | 5nd4B-5n5nB:56.3 | 5nd4B-5n5nB:97.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 7 | VAL B 23GLU B 27HIS B 229ALA B 233PHE B 272ARG B 320PRO B 360 | None | 0.96A | 5nd4B-5n5nB:56.3 | 5nd4B-5n5nB:97.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 6 | VAL B 23HIS B 229ALA B 233SER B 236PHE B 272PRO B 360 | None | 0.80A | 5nd4B-5n5nB:56.3 | 5nd4B-5n5nB:97.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 7 | VAL B 23HIS B 229LEU B 230ALA B 233PHE B 272ARG B 320PRO B 360 | None | 0.85A | 5nd4B-5n5nB:56.3 | 5nd4B-5n5nB:97.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 7 | VAL B 23LEU B 230ALA B 233PHE B 272ARG B 320PRO B 360LEU B 371 | None | 0.98A | 5nd4B-5n5nB:56.3 | 5nd4B-5n5nB:97.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ncc | FATTY ACIDPHOTODECARBOXYLASE (Chlorellavariabilis) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | GLU A 114LEU A 98ALA A 95ARG A 109LEU A 113 | FAD A 701 (-2.6A)NoneNoneNoneNone | 1.18A | 5nd4B-5nccA:undetectable | 5nd4B-5nccA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5sv2 | RIBONUCLEASE VAPC21 (Mycobacteriumtuberculosis) |
PF01850(PIN) | 5 | ASP A 40GLU A 42LEU A 24ALA A 12ARG A 4 | None | 1.30A | 5nd4B-5sv2A:undetectable | 5nd4B-5sv2A:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6s | UDP-GLYCOSYLTRANSFERASE 74F2 (Arabidopsisthaliana) |
PF00201(UDPGT) | 5 | VAL A 8LEU A 38ALA A 10PHE A 22ARG A 28 | None | 1.30A | 5nd4B-5u6sA:4.8 | 5nd4B-5u6sA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v57 | SMOOTHENEDHOMOLOG,FLAVODOXIN,SMOOTHENED HOMOLOG (Desulfovibriovulgaris;Homo sapiens) |
PF00258(Flavodoxin_1)PF01392(Fz)PF01534(Frizzled) | 5 | VAL A 210ASP A 209GLU A 211ALA A 115PRO A 153 | None | 1.30A | 5nd4B-5v57A:4.4 | 5nd4B-5v57A:20.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vfa | RESPONSE REGULATOR (Streptococcuspneumoniae) |
no annotation | 5 | VAL A 32ASP A 30LEU A 56ALA A 38PHE A 64 | None | 1.31A | 5nd4B-5vfaA:4.3 | 5nd4B-5vfaA:11.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5voc | ENVELOPEGLYCOPROTEIN H (Humanbetaherpesvirus5) |
PF02489(Herpes_glycop_H)PF17488(Herpes_glycoH_C) | 5 | VAL A 490GLU A 486ALA A 447ARG A 441LEU A 440 | None | 1.11A | 5nd4B-5vocA:undetectable | 5nd4B-5vocA:19.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w3j | TUBULIN BETA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 6 | VAL B 23ASP B 26GLU B 27LEU B 228ARG B 318LEU B 361 | TA1 B 502 (-3.9A)TA1 B 502 (-4.1A)TA1 B 502 (-3.6A)NoneNoneTA1 B 502 (-3.7A) | 1.11A | 5nd4B-5w3jB:56.0 | 5nd4B-5w3jB:77.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w3j | TUBULIN BETA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 6 | VAL B 23ASP B 26LEU B 228ARG B 318PRO B 358LEU B 361 | TA1 B 502 (-3.9A)TA1 B 502 (-4.1A)NoneNoneNoneTA1 B 502 (-3.7A) | 1.10A | 5nd4B-5w3jB:56.0 | 5nd4B-5w3jB:77.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5w3j | TUBULIN BETA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 6 | VAL B 23ASP B 26SER B 234ARG B 318PRO B 358LEU B 361 | TA1 B 502 (-3.9A)TA1 B 502 (-4.1A)TA1 B 502 ( 4.9A)NoneNoneTA1 B 502 (-3.7A) | 0.95A | 5nd4B-5w3jB:56.0 | 5nd4B-5w3jB:77.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wbl | REGULATORY-ASSOCIATED PROTEIN OF TOR 1 (Arabidopsisthaliana) |
no annotation | 5 | VAL A1133ASP A1134ALA A1092SER A1076LEU A1034 | None | 1.29A | 5nd4B-5wblA:undetectable | 5nd4B-5wblA:11.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wql | TAIL-SPECIFICPROTEASE (Escherichiacoli) |
no annotation | 5 | VAL C 469LEU C 392ALA C 458ARG C 448ARG C 513 | None | 1.12A | 5nd4B-5wqlC:undetectable | 5nd4B-5wqlC:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wyb | PROBABLE ENOYL-COAHYDRATASE/ISOMERASE (Pseudomonasaeruginosa) |
no annotation | 5 | VAL B 195ASP B 196GLU B 137LEU B 206ALA B 203 | NoneNoneNoneNoneACT B 302 ( 4.4A) | 1.31A | 5nd4B-5wybB:undetectable | 5nd4B-5wybB:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xdr | PRE-MRNA-SPLICINGFACTOR ATP-DEPENDENTRNA HELICASE DHX15 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF04408(HA2)PF07717(OB_NTP_bind) | 5 | VAL A 701LEU A 693ARG A 748PRO A 731LEU A 727 | None | 1.09A | 5nd4B-5xdrA:undetectable | 5nd4B-5xdrA:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eoj | POLYADENYLATIONFACTOR SUBUNIT2,POLYADENYLATIONFACTOR SUBUNIT 2PROTEIN CFT1 (Saccharomycescerevisiae) |
no annotation | 5 | ASP A 62LEU A 117ALA A 83PHE A 109ARG D 74 | None | 1.10A | 5nd4B-6eojA:undetectable | 5nd4B-6eojA:16.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eq8 | PERIPLASMICALPHA-GALACTOSIDE-BINDING PROTEIN (Agrobacteriumtumefaciens) |
no annotation | 5 | ASP D 380GLU D 381LEU D 389ALA D 385ARG D 507 | None | 1.03A | 5nd4B-6eq8D:undetectable | 5nd4B-6eq8D:12.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6req | PROTEIN(METHYLMALONYL-COAMUTASE) (Propionibacteriumfreudenreichii) |
PF01642(MM_CoA_mutase) | 5 | VAL B 463GLU B 498ARG B 472ARG B 492LEU B 367 | None | 1.32A | 5nd4B-6reqB:4.7 | 5nd4B-6reqB:22.68 |