SIMILAR PATTERNS OF AMINO ACIDS FOR 5N5D_A_SAMA306_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1biy | LACTOFERRIN (Bubalus bubalis) |
PF00405(Transferrin) | 4 | LEU A 299PHE A 300GLU A 80ASP A 302 | None | 1.04A | 5n5dA-1biyA:undetectable | 5n5dA-1biyA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1em2 | MLN64 PROTEIN (Homo sapiens) |
PF01852(START) | 4 | LEU A 434PHE A 430ILE A 284ASP A 269 | None | 1.06A | 5n5dA-1em2A:undetectable | 5n5dA-1em2A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i41 | CYSTATHIONINEGAMMA-SYNTHASE (Nicotianatabacum) |
PF01053(Cys_Met_Meta_PP) | 4 | LEU A 133SER A 124ILE A 304ASN A 113 | None | 1.05A | 5n5dA-1i41A:4.4 | 5n5dA-1i41A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ibq | ASPERGILLOPEPSIN (Aspergillusphoenicis) |
PF00026(Asp) | 4 | LEU A 297SER A 293ILE A 289ASP A 223 | None | 1.06A | 5n5dA-1ibqA:undetectable | 5n5dA-1ibqA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jct | GLUCARATEDEHYDRATASE (Escherichiacoli) |
PF13378(MR_MLE_C) | 4 | LEU A 28ILE A 220GLU A 216ASP A 235 | NoneNoneNone MG A 498 ( 2.6A) | 0.87A | 5n5dA-1jctA:undetectable | 5n5dA-1jctA:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lrw | METHANOLDEHYDROGENASESUBUNIT 1 (Paracoccusdenitrificans) |
PF01011(PQQ)PF13360(PQQ_2) | 4 | LEU A 367ILE A 346ASP A 364ASN A 217 | None | 0.95A | 5n5dA-1lrwA:undetectable | 5n5dA-1lrwA:17.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nsa | PROCARBOXYPEPTIDASEB (Sus scrofa) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | SER A 207ILE A 202GLU A 270ASP A 255 | BEN A 1 (-3.5A)None ZN A 501 ( 4.9A)BEN A 1 (-3.1A) | 1.01A | 5n5dA-1nsaA:undetectable | 5n5dA-1nsaA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qr7 | PHENYLALANINE-REGULATED3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE (Escherichiacoli) |
PF00793(DAHP_synth_1) | 4 | LEU A 107PHE A 95ILE A 148ASN A 120 | None | 1.01A | 5n5dA-1qr7A:undetectable | 5n5dA-1qr7A:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rtr | GERANYLTRANSTRANSFERASE (Staphylococcusaureus) |
PF00348(polyprenyl_synt) | 4 | LEU A 63SER A 67ILE A 135ASP A 126 | None | 0.89A | 5n5dA-1rtrA:undetectable | 5n5dA-1rtrA:23.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tx4 | P50-RHOGAP (Homo sapiens) |
PF00620(RhoGAP) | 4 | LEU A 226PHE A 222ILE A 216ASN A 202 | None | 1.02A | 5n5dA-1tx4A:undetectable | 5n5dA-1tx4A:23.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlu | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Saccharomycescerevisiae) |
PF00171(Aldedh) | 4 | SER A 2ILE A 199GLU A 197ASP A 191 | None | 1.06A | 5n5dA-1vluA:undetectable | 5n5dA-1vluA:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xrs | D-LYSINE5,6-AMINOMUTASEALPHA SUBUNIT (Acetoanaerobiumsticklandii) |
PF09043(Lys-AminoMut_A) | 4 | LEU A 7PHE A 9GLU A 13ASN A 462 | None | 0.81A | 5n5dA-1xrsA:undetectable | 5n5dA-1xrsA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y79 | PEPTIDYL-DIPEPTIDASEDCP (Escherichiacoli) |
PF01432(Peptidase_M3) | 4 | LEU 1 90PHE 1 94SER 1 169GLU 1 97 | None | 1.06A | 5n5dA-1y791:undetectable | 5n5dA-1y791:18.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ztc | HYPOTHETICAL PROTEINTM0894 (Thermotogamaritima) |
PF00753(Lactamase_B) | 4 | LEU A 80SER A 114ILE A 107ASN A 41 | None | 0.82A | 5n5dA-1ztcA:undetectable | 5n5dA-1ztcA:22.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2avd | CATECHOL-O-METHYLTRANSFERASE (Homo sapiens) |
PF01596(Methyltransf_3) | 4 | PHE A 112SER A 116GLU A 134ASP A 185 | SAM A 501 (-4.7A)SAM A 501 (-3.0A)SAM A 501 (-2.9A)SAM A 501 (-3.4A) | 0.28A | 5n5dA-2avdA:28.4 | 5n5dA-2avdA:34.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c1h | DELTA-AMINOLEVULINICACID DEHYDRATASE (Prosthecochlorisvibrioformis) |
PF00490(ALAD) | 4 | SER A 158ILE A 103GLU A 96ASP A 100 | None | 1.05A | 5n5dA-2c1hA:2.2 | 5n5dA-2c1hA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gj4 | GLYCOGENPHOSPHORYLASE,MUSCLE FORM (Oryctolaguscuniculus) |
PF00343(Phosphorylase) | 4 | LEU A 652ILE A 125GLU A 124ASP A 128 | None | 0.96A | 5n5dA-2gj4A:3.1 | 5n5dA-2gj4A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gmy | HYPOTHETICAL PROTEINATU0492 (Agrobacteriumfabrum) |
PF02627(CMD) | 4 | ILE A 98GLU A 100ASP A 93ASN A 46 | None | 0.92A | 5n5dA-2gmyA:undetectable | 5n5dA-2gmyA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ngr | PROTEIN (GTPASEACTIVATING PROTEIN(RHG)) (Homo sapiens) |
PF00620(RhoGAP) | 4 | LEU B 446PHE B 442ILE B 436ASN B 422 | None | 1.01A | 5n5dA-2ngrB:undetectable | 5n5dA-2ngrB:21.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pvp | D-ALANINE-D-ALANINELIGASE (Helicobacterpylori) |
PF01820(Dala_Dala_lig_N)PF07478(Dala_Dala_lig_C) | 4 | LEU A 279PHE A 280ILE A 117ASP A 281 | None | 0.96A | 5n5dA-2pvpA:undetectable | 5n5dA-2pvpA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qhp | FRUCTOKINASE (Bacteroidesthetaiotaomicron) |
PF00294(PfkB) | 4 | LEU A 164PHE A 168ILE A 149ASN A 153 | NoneEDO A 298 ( 4.9A)NoneNone | 1.02A | 5n5dA-2qhpA:3.9 | 5n5dA-2qhpA:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsi | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATECYTIDYLYLTRANSFERASE (Streptococcuspneumoniae) |
PF01128(IspD) | 4 | ILE A 107GLU A 105ASP A 134ASN A 132 | None | 0.94A | 5n5dA-2vsiA:3.4 | 5n5dA-2vsiA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wbv | FIBER PROTEIN (CaninemastadenovirusA) |
no annotation | 4 | LEU A 512PHE A 514SER A 419ILE A 477 | NoneNoneSIA A1545 (-4.4A)None | 1.06A | 5n5dA-2wbvA:undetectable | 5n5dA-2wbvA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b4w | ALDEHYDEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF00171(Aldedh) | 4 | LEU A 415SER A 411ILE A 388GLU A 387 | NAD A 500 ( 4.6A)NoneNoneNAD A 500 (-2.8A) | 0.99A | 5n5dA-3b4wA:5.3 | 5n5dA-3b4wA:18.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3bwm | CATECHOLO-METHYLTRANSFERASE (Homo sapiens) |
PF01596(Methyltransf_3) | 4 | SER A 72ILE A 89GLU A 90ASP A 141 | SAM A 301 (-2.9A)SAM A 301 ( 4.9A)SAM A 301 (-2.8A) MG A 300 (-2.4A) | 0.29A | 5n5dA-3bwmA:22.8 | 5n5dA-3bwmA:30.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c3y | O-METHYLTRANSFERASE (Mesembryanthemumcrystallinum) |
PF01596(Methyltransf_3) | 4 | PHE A 80SER A 84ILE A 101ASP A 154 | SAH A 464 (-4.9A)SAH A 464 (-2.8A)None CA A 238 ( 2.2A) | 0.40A | 5n5dA-3c3yA:27.3 | 5n5dA-3c3yA:27.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cem | GLYCOGENPHOSPHORYLASE, LIVERFORM (Homo sapiens) |
PF00343(Phosphorylase) | 4 | LEU A 652ILE A 125GLU A 124ASP A 128 | None | 0.91A | 5n5dA-3cemA:3.2 | 5n5dA-3cemA:15.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e3b | CASEIN KINASE IISUBUNIT ALPHA' (Homo sapiens) |
PF00069(Pkinase) | 4 | ILE X 85GLU X 181ASP X 26ASN X 17 | None | 1.05A | 5n5dA-3e3bX:undetectable | 5n5dA-3e3bX:20.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eqz | RESPONSE REGULATOR (Colwelliapsychrerythraea) |
PF00072(Response_reg) | 4 | LEU A 41SER A 72ILE A 77ASP A 47 | LEU A 41 ( 0.6A)SER A 72 ( 0.0A)ILE A 77 ( 0.7A)ASP A 47 ( 0.6A) | 0.94A | 5n5dA-3eqzA:3.2 | 5n5dA-3eqzA:22.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f7w | PUTATIVEFRUCTOSAMINE-3-KINASE (Thermobifidafusca) |
PF03881(Fructosamin_kin) | 4 | LEU A 86SER A 25ILE A 127ASP A 210 | None | 0.99A | 5n5dA-3f7wA:undetectable | 5n5dA-3f7wA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gg9 | D-3-PHOSPHOGLYCERATEDEHYDROGENASEOXIDOREDUCTASEPROTEIN (Ralstoniasolanacearum) |
PF00389(2-Hacid_dh)PF02826(2-Hacid_dh_C) | 4 | LEU A 234ILE A 98GLU A 66ASP A 93 | None | 1.03A | 5n5dA-3gg9A:5.1 | 5n5dA-3gg9A:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gtu | GLUTATHIONES-TRANSFERASE (Homo sapiens) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU B 23PHE B 161ILE B 166ASN B 77 | None | 0.91A | 5n5dA-3gtuB:undetectable | 5n5dA-3gtuB:17.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7l | ENDOGLUCANASE (Vibrioparahaemolyticus) |
PF00759(Glyco_hydro_9)PF02927(CelD_N) | 4 | PHE A 409ILE A 480ASP A 475ASN A 6 | None | 1.00A | 5n5dA-3h7lA:undetectable | 5n5dA-3h7lA:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ju1 | ENOYL-COAHYDRATASE/ISOMERASEFAMILY PROTEIN (Shewanellaoneidensis) |
PF16113(ECH_2) | 4 | LEU A 315PHE A 319GLU A 322ASN A 173 | None | 0.95A | 5n5dA-3ju1A:undetectable | 5n5dA-3ju1A:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ku0 | RIBOSOME-INACTIVATING PROTEIN GELONIN (Suregadamultiflora) |
PF00161(RIP) | 4 | LEU A 63ILE A 135ASP A 141ASN A 60 | None | 1.06A | 5n5dA-3ku0A:undetectable | 5n5dA-3ku0A:22.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kxi | GTP-BINDING PROTEIN(HFLX) (Sulfolobussolfataricus) |
PF01926(MMR_HSR1)PF13167(GTP-bdg_N)PF16360(GTP-bdg_M) | 4 | LEU A 274SER A 320ILE A 331ASN A 300 | NoneNoneNoneGDP A 500 (-3.0A) | 0.98A | 5n5dA-3kxiA:2.6 | 5n5dA-3kxiA:18.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm7 | PUTATIVE4-HYDROXY-2-OXOGLUTARATE ALDOLASE /2-DEHYDRO-3-DEOXYPHOSPHOGLUCONATEALDOLASE (Yersiniaenterocolitica) |
PF07071(KDGP_aldolase) | 4 | ILE A 221GLU A 232ASP A 223ASN A 23 | None | 1.07A | 5n5dA-3lm7A:2.3 | 5n5dA-3lm7A:22.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lms | CARBOXYPEPTIDASE B2 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | SER A 207ILE A 202GLU A 270ASP A 255 | NoneNoneGLY A 501 ( 4.6A)None | 0.91A | 5n5dA-3lmsA:undetectable | 5n5dA-3lmsA:19.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pih | UVRABC SYSTEMPROTEIN A (Thermotogamaritima) |
PF00005(ABC_tran) | 4 | LEU A 152SER A 221ILE A 209ASN A 237 | None | 1.02A | 5n5dA-3pihA:undetectable | 5n5dA-3pihA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s2j | DIPEPTIDASE (Streptomycescoelicolor) |
PF01244(Peptidase_M19) | 4 | LEU A 186SER A 190ILE A 317ASN A 361 | None | 0.97A | 5n5dA-3s2jA:undetectable | 5n5dA-3s2jA:24.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3two | MANNITOLDEHYDROGENASE (Helicobacterpylori) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | PHE A 337ILE A 41ASP A 316ASN A 329 | None | 0.94A | 5n5dA-3twoA:7.7 | 5n5dA-3twoA:18.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vz0 | PUTATIVENAD-DEPENDENTALDEHYDEDEHYDROGENASE (Gluconobacteroxydans) |
PF00171(Aldedh) | 4 | LEU A 389SER A 385ILE A 362GLU A 361 | None | 0.93A | 5n5dA-3vz0A:6.0 | 5n5dA-3vz0A:20.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a0l | CULLIN-4B (Homo sapiens) |
PF00888(Cullin)PF10557(Cullin_Nedd8) | 4 | SER E 282ILE E 354GLU E 355ASP E 348 | None | 0.73A | 5n5dA-4a0lE:undetectable | 5n5dA-4a0lE:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d5r | A49 (Vaccinia virus) |
PF06489(Orthopox_A49R) | 4 | LEU A 65PHE A 61ILE A 42ASN A 49 | None | 0.93A | 5n5dA-4d5rA:undetectable | 5n5dA-4d5rA:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e1t | INVASIN (Yersiniapseudotuberculosis) |
PF11924(IAT_beta) | 4 | LEU A 301PHE A 302GLU A 341ASN A 384 | None | 1.05A | 5n5dA-4e1tA:undetectable | 5n5dA-4e1tA:24.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6e | SUPEROXIDE DISMUTASE[MN], MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00081(Sod_Fe_N)PF02777(Sod_Fe_C) | 4 | LEU A 103PHE A 202ILE A 207ASN A 87 | NoneMLY A 138 ( 3.9A)MLY A 206 ( 4.0A)None | 1.01A | 5n5dA-4f6eA:undetectable | 5n5dA-4f6eA:21.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hn8 | D-GLUCARATEDEHYDRATASE (Pseudomonasmendocina) |
PF13378(MR_MLE_C) | 4 | LEU A 30ILE A 237GLU A 233ASP A 252 | None | 0.98A | 5n5dA-4hn8A:undetectable | 5n5dA-4hn8A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jyl | ENOYL-COA HYDRATASE (Thermoplasmavolcanium) |
PF00378(ECH_1) | 4 | ILE A 5GLU A 4ASP A 32ASN A -5 | None | 0.86A | 5n5dA-4jylA:undetectable | 5n5dA-4jylA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nrh | COPNCHAPERONE SYCD (Chlamydiapneumoniae;Chlamydiapneumoniae) |
PF07201(HrpJ)PF07720(TPR_3) | 4 | SER B 51ILE A 136GLU A 111ASN A 104 | None | 1.04A | 5n5dA-4nrhB:undetectable | 5n5dA-4nrhB:23.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o89 | RNA 3'-TERMINALPHOSPHATE CYCLASE (Pyrococcushorikoshii) |
PF01137(RTC)PF05189(RTC_insert) | 4 | LEU A 140PHE A 291SER A 295ILE A 335 | None | 0.92A | 5n5dA-4o89A:4.0 | 5n5dA-4o89A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oht | SUCCINATE-SEMIALDEHYDE DEHYDROGENASE (Streptococcuspyogenes) |
PF00171(Aldedh) | 4 | LEU A 388SER A 384ILE A 361GLU A 360 | None | 1.07A | 5n5dA-4ohtA:5.5 | 5n5dA-4ohtA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pav | GLYOXALASE FAMILYPROTEIN (Staphylococcusaureus) |
PF00903(Glyoxalase) | 4 | SER A 17ILE A 51GLU A 52ASP A 116 | None | 0.92A | 5n5dA-4pavA:undetectable | 5n5dA-4pavA:18.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4pcl | O-METHYLTRANSFERASEFAMILY PROTEIN (Anaplasmaphagocytophilum) |
PF01596(Methyltransf_3) | 4 | LEU A 35ILE A 87GLU A 88ASN A 138 | NoneNoneSAM A 301 (-2.6A)SAM A 301 (-3.4A) | 1.01A | 5n5dA-4pclA:29.6 | 5n5dA-4pclA:31.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4pcl | O-METHYLTRANSFERASEFAMILY PROTEIN (Anaplasmaphagocytophilum) |
PF01596(Methyltransf_3) | 5 | SER A 70ILE A 87GLU A 88ASP A 136ASN A 138 | SAM A 301 (-2.9A)NoneSAM A 301 (-2.6A) MN A 303 ( 2.7A)SAM A 301 (-3.4A) | 0.22A | 5n5dA-4pclA:29.6 | 5n5dA-4pclA:31.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ptf | DNA POLYMERASEEPSILON CATALYTICSUBUNIT A (Saccharomycescerevisiae) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | LEU A 439PHE A 377ILE A 374ASP A 290 | NoneNoneNone CA A1204 (-2.8A) | 0.95A | 5n5dA-4ptfA:undetectable | 5n5dA-4ptfA:11.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4puc | SUSD HOMOLOG (Bacteroidesuniformis) |
PF12741(SusD-like) | 4 | PHE A 67SER A 107ILE A 58ASP A 61 | None | 0.86A | 5n5dA-4pucA:undetectable | 5n5dA-4pucA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxq | D-GLUCURONYL C5EPIMERASE B (Danio rerio) |
PF06662(C5-epim_C) | 4 | LEU A 484SER A 420ILE A 181ASN A 478 | NoneNoneSGN A 802 (-4.4A)UAP A 801 ( 4.6A) | 1.04A | 5n5dA-4pxqA:undetectable | 5n5dA-4pxqA:16.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qti | UROKINASEPLASMINOGENACTIVATOR SURFACERECEPTOR (Homo sapiens) |
PF00021(UPAR_LY6) | 4 | LEU U 184PHE U 165ILE U 130ASN U 162 | None | 0.89A | 5n5dA-4qtiU:undetectable | 5n5dA-4qtiU:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r2h | STIV B204 ATPASE (Sulfolobusturretedicosahedralvirus 1) |
no annotation | 4 | PHE A 53ILE A 37ASP A 40ASN A 56 | None | 1.06A | 5n5dA-4r2hA:3.0 | 5n5dA-4r2hA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rl1 | TYPE I POLYKETIDESYNTHASE AVES 1 (Streptomycesavermitilis) |
PF00698(Acyl_transf_1) | 4 | LEU A 263SER A 130ILE A 124GLU A 123 | None | 0.97A | 5n5dA-4rl1A:undetectable | 5n5dA-4rl1A:26.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wat | PFRH5 (Plasmodiumfalciparum) |
no annotation | 4 | LEU A 479SER A 485ILE A 235GLU A 416 | NoneIMD A1102 (-3.0A)NoneNone | 1.05A | 5n5dA-4watA:undetectable | 5n5dA-4watA:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wd1 | ACETOACETATE-COALIGASE (Streptomyceslividans) |
PF00501(AMP-binding)PF13193(AMP-binding_C)PF16177(ACAS_N) | 4 | LEU A 437SER A 419ILE A 441GLU A 443 | EDO A 705 (-4.1A)EDO A 706 (-3.4A)NoneNone | 1.06A | 5n5dA-4wd1A:4.4 | 5n5dA-4wd1A:17.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xfe | TRAP DICARBOXYLATETRANSPORTER SUBUNITDCTP (Pseudomonasputida) |
PF03480(DctP) | 4 | LEU A 175PHE A 176ILE A 188ASN A 181 | None | 1.06A | 5n5dA-4xfeA:undetectable | 5n5dA-4xfeA:20.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ymg | PUTATIVESAM-DEPENDENTO-METHYLTRANFERASE (Podosporaanserina) |
PF01596(Methyltransf_3) | 4 | SER A 79GLU A 98ASP A 144ASN A 146 | SAM A1001 (-2.7A)SAM A1001 (-2.7A)SAM A1001 (-3.6A)SAM A1001 ( 3.5A) | 0.15A | 5n5dA-4ymgA:25.4 | 5n5dA-4ymgA:30.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yzf | BAND 3 ANIONTRANSPORT PROTEIN (Homo sapiens) |
PF00955(HCO3_cotransp) | 4 | LEU A 530PHE A 526SER A 799ILE A 684 | None | 0.93A | 5n5dA-4yzfA:undetectable | 5n5dA-4yzfA:13.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z64 | PHYTOSULFOKINERECEPTOR 1 (Arabidopsisthaliana) |
PF00560(LRR_1)PF08263(LRRNT_2)PF13855(LRR_8) | 4 | LEU A 336ILE A 316ASP A 338ASN A 311 | NoneNoneNoneNAG A 705 (-1.8A) | 1.05A | 5n5dA-4z64A:undetectable | 5n5dA-4z64A:17.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zht | BIFUNCTIONALUDP-N-ACETYLGLUCOSAMINE2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE (Homo sapiens) |
PF02350(Epimerase_2) | 4 | SER A 229ILE A 142GLU A 81ASP A 225 | None | 0.92A | 5n5dA-4zhtA:2.8 | 5n5dA-4zhtA:19.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zi6 | CYTOSOLAMINOPEPTIDASE (Helicobacterpylori) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | LEU A 260SER A 286ILE A 187ASN A 235 | ZN A 501 ( 4.8A)NoneNoneNone | 0.97A | 5n5dA-4zi6A:2.2 | 5n5dA-4zi6A:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amq | RNA POLYMERASE L (Californiaencephalitisorthobunyavirus) |
PF04196(Bunya_RdRp)PF15518(L_protein_N) | 4 | LEU A1001ILE A1193GLU A1056ASN A1189 | None | 0.99A | 5n5dA-5amqA:undetectable | 5n5dA-5amqA:7.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5axh | DEXTRANASE (Thermoanaerobacterpseudethanolicus) |
PF13199(Glyco_hydro_66) | 4 | LEU A 458PHE A 420SER A 461ASN A 541 | NoneNonePO4 A 705 ( 2.6A)None | 1.05A | 5n5dA-5axhA:undetectable | 5n5dA-5axhA:15.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5clw | 1,4-ALPHA-GLUCAN-BRANCHING ENZYME (Homo sapiens) |
PF00128(Alpha-amylase)PF02806(Alpha-amylase_C)PF02922(CBM_48) | 4 | SER A 255ILE A 176ASP A 298ASN A 170 | None | 0.93A | 5n5dA-5clwA:undetectable | 5n5dA-5clwA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dgo | CELL DIVISIONCONTROL PROTEIN 45HOMOLOG (Homo sapiens) |
PF02724(CDC45) | 5 | LEU A 311PHE A 300SER A 304ILE A 430ASN A 292 | None | 1.48A | 5n5dA-5dgoA:undetectable | 5n5dA-5dgoA:18.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5do7 | ATP-BINDING CASSETTESUB-FAMILY G MEMBER5 (Homo sapiens) |
PF00005(ABC_tran)PF01061(ABC2_membrane) | 4 | LEU A 422PHE A 426SER A 572ILE A 539 | None | 1.05A | 5n5dA-5do7A:undetectable | 5n5dA-5do7A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ejy | MYOSIN-I HEAVY CHAIN (Dictyosteliumdiscoideum) |
PF00784(MyTH4) | 4 | SER A 305ILE A 253ASP A 302ASN A 216 | None | 1.01A | 5n5dA-5ejyA:undetectable | 5n5dA-5ejyA:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5g | PUTATIVE XANTHINEDEHYDROGENASE YAGTIRON-SULFUR-BINDINGSUBUNITPUTATIVE XANTHINEDEHYDROGENASE YAGRMOLYBDENUM-BINDINGSU SUBUNIT (Escherichiacoli;Escherichiacoli) |
PF00111(Fer2)PF01799(Fer2_2)PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 4 | LEU B 96SER B 236ILE A 199GLU A 198 | None | 0.72A | 5n5dA-5g5gB:undetectable | 5n5dA-5g5gB:24.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h1z | PUTATIVE CYP ALKANEHYDROXYLASECYP153D17 (Sphingomonassp. PAMC 26605) |
PF00067(p450) | 4 | LEU A 157SER A 219GLU A 114ASN A 121 | None | 1.05A | 5n5dA-5h1zA:undetectable | 5n5dA-5h1zA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5has | SEC7 (Thielaviaterrestris) |
PF12783(Sec7_N)PF16213(DCB) | 4 | LEU A 346PHE A 316SER A 320ILE A 380 | None | 0.96A | 5n5dA-5hasA:undetectable | 5n5dA-5hasA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ikp | GLYCOGENPHOSPHORYLASE, BRAINFORM (Homo sapiens) |
PF00343(Phosphorylase) | 4 | LEU A 652ILE A 125GLU A 124ASP A 128 | None | 0.95A | 5n5dA-5ikpA:undetectable | 5n5dA-5ikpA:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5izd | D-GLYCERALDEHYDEDEHYDROGENASE(NADP(+)) (Thermoplasmaacidophilum) |
PF00171(Aldedh) | 4 | LEU A 409SER A 405ILE A 382GLU A 381 | None | 0.87A | 5n5dA-5izdA:5.6 | 5n5dA-5izdA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j55 | CAROTENOID OXYGENASE (Novosphingobiumaromaticivorans) |
PF03055(RPE65) | 4 | PHE A 309SER A 9ASP A 56ASN A 103 | None | 0.99A | 5n5dA-5j55A:undetectable | 5n5dA-5j55A:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j84 | DIHYDROXY-ACIDDEHYDRATASE (Rhizobiumleguminosarum) |
PF00920(ILVD_EDD) | 4 | LEU A 40PHE A 80SER A 13ILE A 244 | None | 1.00A | 5n5dA-5j84A:2.4 | 5n5dA-5j84A:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8b | ALPHA-L-ARABINOFURANOSIDASE II (Lactobacillusbrevis) |
PF04616(Glyco_hydro_43) | 4 | LEU A 140PHE A 138ILE A 162ASN A 201 | TRS A 402 (-4.3A)NoneNoneNone | 1.04A | 5n5dA-5m8bA:undetectable | 5n5dA-5m8bA:21.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8e | ALPHA-N-ARABINOFURANOSIDASE (Weissellacibaria) |
PF04616(Glyco_hydro_43) | 4 | LEU A 138PHE A 136ILE A 160ASN A 199 | GOL A 404 (-4.3A)GOL A 404 (-4.0A)NoneNone | 1.03A | 5n5dA-5m8eA:undetectable | 5n5dA-5m8eA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mc9 | LAMININ SUBUNITALPHA-1 (Mus musculus) |
PF00054(Laminin_G_1)PF06009(Laminin_II) | 4 | PHE A2217SER A2517ILE A2214ASN A2286 | None | 1.03A | 5n5dA-5mc9A:undetectable | 5n5dA-5mc9A:18.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqc | VP1VP2VP3 (Black queencell virus;Black queencell virus;Black queencell virus) |
PF08762(CRPV_capsid)PF00073(Rhv)no annotation | 4 | LEU C 257ILE A 74GLU A 111ASN B 139 | None | 0.90A | 5n5dA-5mqcC:undetectable | 5n5dA-5mqcC:20.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5d | METHYLTRANSFERASE (Streptomycesregensis) |
PF01596(Methyltransf_3) | 4 | LEU A 39PHE A 67SER A 71ILE A 64 | SAM A 306 (-3.5A)SAM A 306 (-4.2A)SAM A 306 (-2.2A)None | 0.82A | 5n5dA-5n5dA:43.4 | 5n5dA-5n5dA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5d | METHYLTRANSFERASE (Streptomycesregensis) |
PF01596(Methyltransf_3) | 7 | LEU A 39PHE A 67SER A 71ILE A 88GLU A 89ASP A 139ASN A 141 | SAM A 306 (-3.5A)SAM A 306 (-4.2A)SAM A 306 (-2.2A)SAM A 306 ( 4.2A)SAM A 306 (-2.4A)SAM A 306 (-2.3A)SAM A 306 ( 2.9A) | 0.00A | 5n5dA-5n5dA:43.4 | 5n5dA-5n5dA:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5n5d | METHYLTRANSFERASE (Streptomycesregensis) |
PF01596(Methyltransf_3) | 5 | PHE A 67SER A 72ILE A 88GLU A 89ASN A 141 | SAM A 306 (-4.2A)NoneSAM A 306 ( 4.2A)SAM A 306 (-2.4A)SAM A 306 ( 2.9A) | 1.16A | 5n5dA-5n5dA:43.4 | 5n5dA-5n5dA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o1p | ALPHA-AMINOADIPICSEMIALDEHYDESYNTHASE,MITOCHONDRIAL (Homo sapiens) |
PF03435(Sacchrp_dh_NADP)PF16653(Sacchrp_dh_C) | 4 | ILE A 507GLU A 506ASP A 548ASN A 504 | None | 1.00A | 5n5dA-5o1pA:7.0 | 5n5dA-5o1pA:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5v57 | SMOOTHENEDHOMOLOG,FLAVODOXIN,SMOOTHENED HOMOLOG (Desulfovibriovulgaris;Homo sapiens) |
PF00258(Flavodoxin_1)PF01392(Fz)PF01534(Frizzled) | 4 | LEU A 221PHE A 222SER A 385GLU A 226 | 836 A1201 (-4.8A)NoneNoneNone | 1.06A | 5n5dA-5v57A:undetectable | 5n5dA-5v57A:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vf3 | MAJOR CAPSID PROTEIN (Escherichiavirus T4) |
PF07068(Gp23) | 4 | PHE A 434ILE A 425ASP A 432ASN A 384 | None | 1.00A | 5n5dA-5vf3A:undetectable | 5n5dA-5vf3A:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vgz | 26S PROTEASOMEREGULATORY SUBUNIT 726S PROTEASOMEREGULATORY SUBUNIT 4 (Homo sapiens;Homo sapiens) |
no annotationno annotation | 4 | LEU A 153ILE B 115GLU B 114ASP B 118 | None | 1.05A | 5n5dA-5vgzA:undetectable | 5n5dA-5vgzA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wab | PUTATIVEBETA-GLUCOSIDASE (Bifidobacteriumadolescentis) |
no annotation | 4 | LEU A 471SER A 78ILE A 498GLU A 468 | None | 0.97A | 5n5dA-5wabA:undetectable | 5n5dA-5wabA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x00 | NUCLEOSIDEDIPHOSPHATE KINASE (Vibrio cholerae) |
no annotation | 4 | LEU A 63SER A 69ILE A 10ASN A 114 | None | 0.90A | 5n5dA-5x00A:undetectable | 5n5dA-5x00A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zji | CHLOROPHYLL A-BBINDING PROTEIN,CHLOROPLASTIC (Zea mays) |
no annotation | 4 | LEU 4 178SER 4 166ILE 4 155ASP 4 160 | CHL 4 618 ( 3.8A)NoneCHL 1 601 (-4.1A)CHL 4 608 (-3.8A) | 1.04A | 5n5dA-5zji4:undetectable | 5n5dA-5zji4:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zw4 | PUTATIVEO-METHYLTRANSFERASEYRRM (Bacillussubtilis) |
no annotation | 4 | SER A 68ILE A 84GLU A 85ASP A 133 | SAM A 302 (-2.7A)SAM A 302 ( 4.7A)SAM A 302 (-2.7A)SAM A 302 (-3.6A) | 0.15A | 5n5dA-5zw4A:25.0 | 5n5dA-5zw4A:28.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6a91 | - (-) |
no annotation | 4 | LEU A 662PHE A 663SER A 690ILE A 668 | None | 0.89A | 5n5dA-6a91A:undetectable | 5n5dA-6a91A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c6l | V-TYPE PROTON ATPASESUBUNIT A, VACUOLARISOFORM (Saccharomycescerevisiae) |
no annotation | 4 | PHE A 19SER A 29ILE A 334ASN A 327 | None | 0.94A | 5n5dA-6c6lA:undetectable | 5n5dA-6c6lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d35 | SMOOTHENED,SOLUBLECYTOCHROMEB562,SMOOTHENED (Escherichiacoli;Xenopus laevis) |
no annotation | 4 | LEU A 194PHE A 195SER A 358GLU A 199 | None | 1.00A | 5n5dA-6d35A:undetectable | 5n5dA-6d35A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gsw | MU CLASS GLUTATHIONES-TRANSFERASE OFISOENZYME 3-3 (Rattus rattus) |
PF00043(GST_C)PF02798(GST_N) | 4 | LEU A 19PHE A 157ILE A 162ASN A 73 | None | 0.90A | 5n5dA-6gswA:undetectable | 5n5dA-6gswA:23.46 |