SIMILAR PATTERNS OF AMINO ACIDS FOR 5N4T_B_BEZB306

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxe 2-DEHYDRO-3-DEOXY-GA
LACTARATE ALDOLASE

(Escherichia
coli) 		PF03328
(HpcH_HpaI) 		3 HIS A 201
ASN A 204
ALA A 208
 None
 0.41A 5n4tB-1dxeA:
1.5		 5n4tB-1dxeA:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fs5 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Escherichia
coli) 		PF01182
(Glucosamine_iso) 		3 HIS A  19
ASN A  22
ALA A  26
 None
 0.30A 5n4tB-1fs5A:
undetectable		 5n4tB-1fs5A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gqj ALPHA-D-GLUCURONIDAS
E

(Cellvibrio
japonicus) 		PF03648
(Glyco_hydro_67N)
PF07477
(Glyco_hydro_67C)
PF07488
(Glyco_hydro_67M) 		3 HIS A 159
ASN A 446
ALA A 172
 None
 0.47A 5n4tB-1gqjA:
0.3		 5n4tB-1gqjA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hxi PEROXISOME TARGETING
SIGNAL 1 RECEPTOR
PEX5

(Trypanosoma
brucei) 		no annotation 3 HIS A 431
ASN A 434
ALA A 438
 None
 0.47A 5n4tB-1hxiA:
undetectable		 5n4tB-1hxiA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j3j BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Plasmodium
falciparum) 		PF00303
(Thymidylat_synt) 		3 HIS C 556
ASN C 555
ALA C 607
 None
 0.82A 5n4tB-1j3jC:
undetectable		 5n4tB-1j3jC:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5w GLYCYL-TRNA
SYNTHETASE ALPHA
CHAIN

(Thermotoga
maritima) 		PF02091
(tRNA-synt_2e) 		3 HIS A 241
ASN A 244
ALA A 248
 None
 0.37A 5n4tB-1j5wA:
undetectable		 5n4tB-1j5wA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jsx GLUCOSE-INHIBITED
DIVISION PROTEIN B

(Escherichia
coli) 		PF02527
(GidB) 		3 HIS A  19
ASN A  22
ALA A  26
 None
 0.17A 5n4tB-1jsxA:
undetectable		 5n4tB-1jsxA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldj CULLIN HOMOLOG 1

(Homo sapiens) 		PF00888
(Cullin)
PF10557
(Cullin_Nedd8) 		3 HIS A 343
ASN A 346
ALA A 350
 None
 0.51A 5n4tB-1ldjA:
undetectable		 5n4tB-1ldjA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldk CULLIN HOMOLOG

(Homo sapiens) 		PF00888
(Cullin) 		3 HIS A 343
ASN A 346
ALA A 350
 None
 0.24A 5n4tB-1ldkA:
undetectable		 5n4tB-1ldkA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lml LEISHMANOLYSIN

(Leishmania
major) 		PF01457
(Peptidase_M8) 		3 HIS A 527
ASN A 481
ALA A 473
 None
 0.80A 5n4tB-1lmlA:
undetectable		 5n4tB-1lmlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m9q ENDOTHELIAL
NITRIC-OXIDE
SYNTHASE

(Homo sapiens) 		PF02898
(NO_synthase) 		3 HIS A 430
ASN A 433
ALA A 437
 None
 0.47A 5n4tB-1m9qA:
undetectable		 5n4tB-1m9qA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nl3 PREPROTEIN
TRANSLOCASE SECA 1
SUBUNIT

(Mycobacterium
tuberculosis) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		3 HIS A 558
ASN A 486
ALA A 488
 None
 0.69A 5n4tB-1nl3A:
undetectable		 5n4tB-1nl3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oyw ATP-DEPENDENT DNA
HELICASE

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF09382
(RQC)
PF16124
(RecQ_Zn_bind) 		3 HIS A 366
ASN A 369
ALA A 373
 None
 0.26A 5n4tB-1oywA:
undetectable		 5n4tB-1oywA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qk1 CREATINE KINASE,
UBIQUITOUS
MITOCHONDRIAL

(Homo sapiens) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 HIS A 214
ASN A 215
ALA A 165
 None
 0.80A 5n4tB-1qk1A:
0.7		 5n4tB-1qk1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		3 HIS A 440
ASN A 443
ALA A 447
 None
 0.52A 5n4tB-1qw5A:
undetectable		 5n4tB-1qw5A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s12 HYPOTHETICAL PROTEIN
TM1457

(Thermotoga
maritima) 		PF04327
(Peptidase_Prp) 		3 HIS A  32
ASN A  35
ALA A  39
 ACT  A 500 (-4.1A)
None
None
 0.30A 5n4tB-1s12A:
undetectable		 5n4tB-1s12A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s35 SPECTRIN BETA CHAIN,
ERYTHROCYTE

(Homo sapiens) 		PF00435
(Spectrin) 		3 HIS A1256
ASN A1259
ALA A1263
 SO4  A 300 (-4.2A)
None
None
 0.37A 5n4tB-1s35A:
undetectable		 5n4tB-1s35A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sf9 YFHH HYPOTHETICAL
PROTEIN

(Bacillus
subtilis) 		PF08838
(DUF1811) 		3 HIS A  35
ASN A  38
ALA A  42
 None
 0.23A 5n4tB-1sf9A:
undetectable		 5n4tB-1sf9A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t1j HYPOTHETICAL PROTEIN

(Pseudomonas
aeruginosa) 		PF09152
(DUF1937) 		3 HIS A  47
ASN A  50
ALA A  54
 None
 0.79A 5n4tB-1t1jA:
undetectable		 5n4tB-1t1jA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmo TRIMETHYLAMINE
N-OXIDE REDUCTASE

(Shewanella
massilia) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 HIS A 447
ASN A 446
ALA A 473
 2MD  A 799 (-4.2A)
2MD  A 799 (-3.8A)
None
 0.74A 5n4tB-1tmoA:
undetectable		 5n4tB-1tmoA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wmr ISOPULLULANASE

(Aspergillus
niger) 		PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N) 		3 HIS A 449
ASN A 448
ALA A 441
 None
NAG  A1004 (-2.1A)
None
 0.82A 5n4tB-1wmrA:
undetectable		 5n4tB-1wmrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a81 CARB

(Pectobacterium
carotovorum) 		PF00378
(ECH_1) 		3 HIS A  17
ASN A  22
ALA A  60
 None
None
ACO  A 500 (-3.7A)
 0.65A 5n4tB-2a81A:
undetectable		 5n4tB-2a81A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2asu HEPATOCYTE GROWTH
FACTOR-LIKE PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		3 HIS B 488
ASN B 620
ALA B 605
 None
 0.80A 5n4tB-2asuB:
undetectable		 5n4tB-2asuB:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c5z SET DOMAIN PROTEIN 2

(Saccharomyces
cerevisiae) 		PF08236
(SRI) 		3 HIS A 630
ASN A 633
ALA A 637
 None
 0.47A 5n4tB-2c5zA:
undetectable		 5n4tB-2c5zA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dk3 E3 UBIQUITIN-PROTEIN
LIGASE HECTD1

(Homo sapiens) 		PF06701
(MIB_HERC2) 		3 HIS A  48
ASN A  49
ALA A  68
 None
 0.49A 5n4tB-2dk3A:
undetectable		 5n4tB-2dk3A:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k3v TETRAHEME CYTOCHROME
C-TYPE

(Shewanella
frigidimarina) 		PF14537
(Cytochrom_c3_2) 		3 HIS A  49
ASN A  48
ALA A  85
 HEM  A 261 (-3.2A)
None
HEM  A 261 ( 2.8A)
 0.81A 5n4tB-2k3vA:
undetectable		 5n4tB-2k3vA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mh3 TRANSCRIPTION FACTOR
HES-1

(Homo sapiens) 		PF00010
(HLH) 		3 HIS A  87
ASN A  90
ALA A  94
 None
 0.71A 5n4tB-2mh3A:
undetectable		 5n4tB-2mh3A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2z HYPOTHETICAL PROTEIN

(Bacillus
halodurans) 		PF01933
(UPF0052) 		3 HIS A  88
ASN A  92
ALA A  96
 None
SO4  A 323 (-3.5A)
None
 0.81A 5n4tB-2o2zA:
undetectable		 5n4tB-2o2zA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p7h HYPOTHETICAL PROTEIN

(Pectobacterium
atrosepticum) 		PF13489
(Methyltransf_23) 		3 HIS A 159
ASN A 160
ALA A 177
 None
 0.73A 5n4tB-2p7hA:
undetectable		 5n4tB-2p7hA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v4j SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT ALPHA
SULFITE REDUCTASE,
DISSIMILATORY-TYPE
SUBUNIT BETA

(Desulfovibrio
vulgaris;
Desulfovibrio
vulgaris) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 HIS A 133
ASN B  99
ALA B  69
 None
 0.54A 5n4tB-2v4jA:
undetectable		 5n4tB-2v4jA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3h K5 LYASE

(Escherichia
virus K1-5) 		no annotation 3 HIS A  86
ASN A 112
ALA A 114
 None
 0.79A 5n4tB-2x3hA:
undetectable		 5n4tB-2x3hA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfb E2 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF00943
(Alpha_E2_glycop) 		3 HIS B 195
ASN B 103
ALA B 105
 None
 0.62A 5n4tB-2xfbB:
undetectable		 5n4tB-2xfbB:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfc E2 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF00943
(Alpha_E2_glycop) 		3 HIS B 195
ASN B 103
ALA B 105
 None
 0.63A 5n4tB-2xfcB:
undetectable		 5n4tB-2xfcB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y35 LD22664P

(Drosophila
melanogaster) 		PF03159
(XRN_N) 		3 HIS A 292
ASN A 287
ALA A 207
 None
 0.66A 5n4tB-2y35A:
undetectable		 5n4tB-2y35A:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbo CYTOCHROME C6

(Sargassum
fusiforme) 		PF13442
(Cytochrome_CBB3) 		3 HIS A  29
ASN A  32
ALA A  36
 None
 0.41A 5n4tB-2zboA:
undetectable		 5n4tB-2zboA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3axs PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1

(Aquifex
aeolicus) 		PF02005
(TRM) 		3 HIS A 110
ASN A  83
ALA A  57
 SO4  A 506 (-3.8A)
SFG  A 501 ( 4.7A)
None
 0.78A 5n4tB-3axsA:
2.0		 5n4tB-3axsA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c37 PEPTIDASE, M48
FAMILY

(Geobacter
sulfurreducens) 		PF01435
(Peptidase_M48) 		3 HIS A 106
ASN A 109
ALA A 113
 ZN  A 301 (-3.2A)
None
None
 0.67A 5n4tB-3c37A:
undetectable		 5n4tB-3c37A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dkm E3 UBIQUITIN-PROTEIN
LIGASE HECTD1

(Homo sapiens) 		PF06701
(MIB_HERC2) 		3 HIS A1308
ASN A1309
ALA A1328
 None
 0.67A 5n4tB-3dkmA:
undetectable		 5n4tB-3dkmA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e5b ISOCITRATE LYASE

(Brucella
abortus) 		PF00463
(ICL) 		3 HIS A 199
ASN A 202
ALA A 206
 None
 0.52A 5n4tB-3e5bA:
undetectable		 5n4tB-3e5bA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e9d ZGC:56074

(Danio rerio) 		PF00300
(His_Phos_1) 		3 HIS A 102
ASN A 105
ALA A 109
 None
 0.40A 5n4tB-3e9dA:
undetectable		 5n4tB-3e9dA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3edt KINESIN LIGHT CHAIN
2

(Homo sapiens) 		PF13374
(TPR_10)
PF13424
(TPR_12) 		3 HIS B 261
ASN B 264
ALA B 268
 None
 0.49A 5n4tB-3edtB:
undetectable		 5n4tB-3edtB:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3emy TRICHODERMA REESEI
ASPARTIC PROTEASE

(Trichoderma
reesei) 		PF00026
(Asp) 		3 HIS A   5
ASN A   4
ALA A   2
 None
 0.70A 5n4tB-3emyA:
undetectable		 5n4tB-3emyA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fc7 HTR-LIKE PROTEIN

(Haloarcula
marismortui) 		PF08448
(PAS_4) 		3 HIS A 218
ASN A 219
ALA A 195
 None
 0.79A 5n4tB-3fc7A:
undetectable		 5n4tB-3fc7A:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fwv HSC70/HSP90-ORGANIZI
NG PROTEIN

(Homo sapiens) 		PF00515
(TPR_1)
PF13424
(TPR_12) 		3 HIS A 321
ASN A 324
ALA A 328
 NI  A   5 (-3.3A)
None
None
 0.28A 5n4tB-3fwvA:
2.2		 5n4tB-3fwvA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g79 NDP-N-ACETYL-D-GALAC
TOSAMINURONIC ACID
DEHYDROGENASE

(Methanosarcina
mazei) 		PF00984
(UDPG_MGDP_dh)
PF03720
(UDPG_MGDP_dh_C)
PF03721
(UDPG_MGDP_dh_N) 		3 HIS A 335
ASN A 338
ALA A 342
 None
 0.40A 5n4tB-3g79A:
undetectable		 5n4tB-3g79A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h6z POLYCOMB PROTEIN
SFMBT

(Drosophila
melanogaster) 		PF02820
(MBT) 		3 HIS A 748
ASN A 749
ALA A 751
 None
 0.79A 5n4tB-3h6zA:
undetectable		 5n4tB-3h6zA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihu TRANSCRIPTIONAL
REGULATOR, GNTR
FAMILY

(Cupriavidus
pinatubonensis) 		PF00392
(GntR)
PF07729
(FCD) 		3 HIS A 207
ASN A 210
ALA A 214
 None
 0.13A 5n4tB-3ihuA:
undetectable		 5n4tB-3ihuA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		3 HIS A1170
ASN A1173
ALA A1177
 None
 0.67A 5n4tB-3jb9A:
undetectable		 5n4tB-3jb9A:
7.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7b PROTEIN A33

(Vaccinia virus) 		PF05966
(Chordopox_A33R) 		3 HIS A 113
ASN A 125
ALA A 128
 None
 0.77A 5n4tB-3k7bA:
undetectable		 5n4tB-3k7bA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kjr DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE

(Babesia bovis) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		3 HIS A 448
ASN A 449
ALA A 451
 None
 0.81A 5n4tB-3kjrA:
undetectable		 5n4tB-3kjrA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m5u PHOSPHOSERINE
AMINOTRANSFERASE

(Campylobacter
jejuni) 		PF00266
(Aminotran_5) 		3 HIS A 260
ASN A 263
ALA A 267
 None
 0.37A 5n4tB-3m5uA:
undetectable		 5n4tB-3m5uA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n40 P62 ENVELOPE
GLYCOPROTEIN

(Chikungunya
virus) 		PF00943
(Alpha_E2_glycop)
PF01563
(Alpha_E3_glycop) 		3 HIS P 195
ASN P 103
ALA P 105
 None
 0.61A 5n4tB-3n40P:
undetectable		 5n4tB-3n40P:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nnk UREIDOGLYCINE-GLYOXY
LATE
AMINOTRANSFERASE

(Klebsiella
pneumoniae) 		PF00266
(Aminotran_5) 		3 HIS A  46
ASN A  49
ALA A  53
 None
 0.14A 5n4tB-3nnkA:
2.0		 5n4tB-3nnkA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o6c PYRIDOXINE
5'-PHOSPHATE
SYNTHASE

(Campylobacter
jejuni) 		PF03740
(PdxJ) 		3 HIS A 152
ASN A 155
ALA A 159
 None
 0.27A 5n4tB-3o6cA:
undetectable		 5n4tB-3o6cA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT ALPHA
SULFITE REDCUTASE
SUBUNIT BETA

(Desulfovibrio
gigas;
Desulfovibrio
gigas) 		PF01077
(NIR_SIR)
PF00037
(Fer4)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 HIS A 133
ASN B  99
ALA B  69
 None
 0.61A 5n4tB-3or2A:
undetectable		 5n4tB-3or2A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pea ENOYL-COA
HYDRATASE/ISOMERASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF00378
(ECH_1) 		3 HIS A  20
ASN A  24
ALA A  61
 None
 0.59A 5n4tB-3peaA:
1.9		 5n4tB-3peaA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pr2 TRYPTOPHAN SYNTHASE
BETA CHAIN

(Salmonella
enterica) 		PF00291
(PALP) 		3 HIS B 342
ASN B  64
ALA B  67
 None
 0.70A 5n4tB-3pr2B:
2.5		 5n4tB-3pr2B:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT

(Coxiella
burnetii) 		PF00574
(CLP_protease) 		3 HIS A  40
ASN A  43
ALA A  47
 None
 0.53A 5n4tB-3q7hA:
undetectable		 5n4tB-3q7hA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qm2 PHOSPHOSERINE
AMINOTRANSFERASE

(Salmonella
enterica) 		PF00266
(Aminotran_5) 		3 HIS A 266
ASN A 269
ALA A 273
 None
 0.34A 5n4tB-3qm2A:
undetectable		 5n4tB-3qm2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rq0 GLYCOSYL HYDROLASES
FAMILY PROTEIN 16

(Mycolicibacterium
smegmatis) 		PF00722
(Glyco_hydro_16) 		3 HIS A 180
ASN A 181
ALA A 183
 None
 0.78A 5n4tB-3rq0A:
undetectable		 5n4tB-3rq0A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufg GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT

(Campylobacter
jejuni) 		PF02091
(tRNA-synt_2e) 		3 HIS A 245
ASN A 248
ALA A 252
 None
 0.32A 5n4tB-3ufgA:
undetectable		 5n4tB-3ufgA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vid VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 HIS A1159
ASN A1162
ALA A1166
 None
 0.22A 5n4tB-3vidA:
undetectable		 5n4tB-3vidA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwz D-LACTATE
DEHYDROGENASE
(FERMENTATIVE)

(Pseudomonas
aeruginosa) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 HIS A  23
ASN A  20
ALA A  18
 None
 0.81A 5n4tB-3wwzA:
undetectable		 5n4tB-3wwzA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzd VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 HIS A1159
ASN A1162
ALA A1166
 None
 0.26A 5n4tB-3wzdA:
undetectable		 5n4tB-3wzdA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4agd VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 HIS A1159
ASN A1162
ALA A1166
 None
 0.41A 5n4tB-4agdA:
undetectable		 5n4tB-4agdA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bax GLUTAMINE SYNTHETASE

(Streptomyces
coelicolor) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		3 HIS A 163
ASN A 166
ALA A 170
 None
 0.38A 5n4tB-4baxA:
undetectable		 5n4tB-4baxA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chl PERSULFIDE
DIOXYGENASE ETHE1,
MITOCHONDRIAL

(Homo sapiens) 		PF00753
(Lactamase_B) 		3 HIS A  81
ASN A 244
ALA A 108
 None
 0.70A 5n4tB-4chlA:
7.0		 5n4tB-4chlA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cqi TUBULIN-BINDING
COFACTOR A

(Leishmania
major) 		PF02970
(TBCA) 		3 HIS A  81
ASN A  84
ALA A  88
 None
 0.17A 5n4tB-4cqiA:
undetectable		 5n4tB-4cqiA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eo4 THREONINE--TRNA
LIGASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00587
(tRNA-synt_2b)
PF03129
(HGTP_anticodon) 		3 HIS A 234
ASN A 108
ALA A 110
 None
 0.73A 5n4tB-4eo4A:
undetectable		 5n4tB-4eo4A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ew7 CONJUGATIVE
TRANSFER: REGULATION

(Salmonella
enterica) 		PF00989
(PAS) 		3 HIS A  87
ASN A 108
ALA A  90
 None
None
PYR  A 203 ( 3.9A)
 0.69A 5n4tB-4ew7A:
undetectable		 5n4tB-4ew7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		3 HIS A 327
ASN A 329
ALA A 331
 None
 0.77A 5n4tB-4lglA:
2.1		 5n4tB-4lglA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nk7 SERINE/THREONINE-PRO
TEIN KINASE PLK4

(Drosophila
melanogaster) 		no annotation 3 HIS A 569
ASN A 572
ALA A 576
 None
 0.74A 5n4tB-4nk7A:
undetectable		 5n4tB-4nk7A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okh CALPAIN-3

(Homo sapiens) 		PF00036
(EF-hand_1)
PF13202
(EF-hand_5)
PF13833
(EF-hand_8) 		3 HIS A 719
ASN A 722
ALA A 726
 None
 0.19A 5n4tB-4okhA:
undetectable		 5n4tB-4okhA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pa1 INTEGRASE

(Feline
immunodeficiency
virus) 		PF00665
(rve) 		3 HIS A 183
ASN A 186
ALA A 197
 None
 0.61A 5n4tB-4pa1A:
1.6		 5n4tB-4pa1A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qtb MITOGEN-ACTIVATED
PROTEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		3 HIS A 197
ASN A 218
ALA A 277
 CL  A 416 (-4.3A)
CL  A 416 (-4.1A)
None
 0.80A 5n4tB-4qtbA:
undetectable		 5n4tB-4qtbA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w65 GLYCOSYL HYDROLASE
FAMILY PROTEIN

(Mycolicibacterium
fortuitum) 		PF00722
(Glyco_hydro_16) 		3 HIS A 193
ASN A 194
ALA A 196
 HIS  A 193 ( 1.0A)
ASN  A 194 ( 0.6A)
ALA  A 196 ( 0.0A)
 0.78A 5n4tB-4w65A:
undetectable		 5n4tB-4w65A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgj UNCHARACTERIZED
PROTEIN

(Pectobacterium
atrosepticum) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		3 HIS A 210
ASN A 213
ALA A 217
 None
 0.19A 5n4tB-4xgjA:
undetectable		 5n4tB-4xgjA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xxp PUTATIVE
UNCHARACTERIZED
PROTEIN (RV0315
ORTHOLOG)

(Mycobacterium
avium) 		PF00722
(Glyco_hydro_16) 		3 HIS A 189
ASN A 190
ALA A 192
 None
 0.78A 5n4tB-4xxpA:
undetectable		 5n4tB-4xxpA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysb METALLO-BETA-LACTAMA
SE FAMILY PROTEIN

(Myxococcus
xanthus) 		PF00753
(Lactamase_B) 		3 HIS A  59
ASN A 220
ALA A  84
 None
 0.64A 5n4tB-4ysbA:
16.0		 5n4tB-4ysbA:
26.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z26 PUTATIVE GMC-TYPE
OXIDOREDUCTASE R135

(Acanthamoeba
polyphaga
mimivirus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		3 HIS A 340
ASN A 616
ALA A 619
 None
FAD  A 901 (-3.9A)
None
 0.79A 5n4tB-4z26A:
undetectable		 5n4tB-4z26A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zfm PUTATIVE
6-PHOSPHO-BETA-GALAC
TOBIOSIDASE

(Geobacillus
stearothermophilus) 		PF00232
(Glyco_hydro_1) 		3 HIS A 199
ASN A 202
ALA A 206
 None
 0.26A 5n4tB-4zfmA:
1.3		 5n4tB-4zfmA:
20.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a87 METALLO-BETA-LACTAMA
SE VIM-5

(Klebsiella
pneumoniae) 		PF00753
(Lactamase_B) 		3 HIS A 251
ASN A 254
ALA A 258
 None
 0.18A 5n4tB-5a87A:
42.9		 5n4tB-5a87A:
93.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5avm PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
CYCLO-LIGASE

(Thermus
thermophilus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		3 HIS A  86
ASN A  89
ALA A  93
 None
 0.44A 5n4tB-5avmA:
undetectable		 5n4tB-5avmA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awp ISOMALTODEXTRANASE

(Arthrobacter
globiformis) 		no annotation 3 HIS A 217
ASN A 221
ALA A 225
 None
 0.81A 5n4tB-5awpA:
undetectable		 5n4tB-5awpA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c6g AGR133CP

(Eremothecium
gossypii) 		PF10345
(Cohesin_load) 		3 HIS A 623
ASN A 626
ALA A 630
 None
 0.43A 5n4tB-5c6gA:
undetectable		 5n4tB-5c6gA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czj DIHYDRODIPICOLINATE
SYNTHASE

(Sinorhizobium
meliloti) 		PF00701
(DHDPS) 		3 HIS A 242
ASN A 245
ALA A 249
 None
 0.34A 5n4tB-5czjA:
3.9		 5n4tB-5czjA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5w GLYCINE--TRNA LIGASE
ALPHA SUBUNIT

(Aquifex
aeolicus) 		PF02091
(tRNA-synt_2e) 		3 HIS A 241
ASN A 244
ALA A 248
 None
 0.19A 5n4tB-5f5wA:
undetectable		 5n4tB-5f5wA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)

(Naja atra) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		3 HIS A 237
ASN A 259
ALA A 227
 None
NAG  A 905 (-1.8A)
None
 0.55A 5n4tB-5gz4A:
undetectable		 5n4tB-5gz4A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tc4 BIFUNCTIONAL
METHYLENETETRAHYDROF
OLATE
DEHYDROGENASE/CYCLOH
YDROLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00763
(THF_DHG_CYH)
PF02882
(THF_DHG_CYH_C) 		3 HIS A  69
ASN A  98
ALA A  92
 None
 0.82A 5n4tB-5tc4A:
undetectable		 5n4tB-5tc4A:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans) 		no annotation 3 HIS B  60
ASN B 225
ALA B  86
 None
 0.71A 5n4tB-5ve3B:
6.0		 5n4tB-5ve3B:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vyq UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		PF00551
(Formyl_trans_N) 		3 HIS A 195
ASN A 198
ALA A 202
 None
EDO  A 303 (-3.1A)
None
 0.33A 5n4tB-5vyqA:
undetectable		 5n4tB-5vyqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w94 MAU2 CHROMATID
COHESION FACTOR
HOMOLOG

(Saccharomyces
cerevisiae) 		PF10345
(Cohesin_load) 		3 HIS A 592
ASN A 595
ALA A 599
 None
 0.31A 5n4tB-5w94A:
undetectable		 5n4tB-5w94A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wyb PROBABLE ENOYL-COA
HYDRATASE/ISOMERASE

(Pseudomonas
aeruginosa) 		no annotation 3 HIS B  34
ASN B  38
ALA B  76
 None
 0.76A 5n4tB-5wybB:
2.3		 5n4tB-5wybB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wz4 23S RRNA-SPECIFIC
ENDONUCLEASE VAPC20

(Mycobacterium
tuberculosis) 		no annotation 3 HIS A  20
ASN A  14
ALA A  56
 None
CSO  A  52 ( 3.2A)
CSO  A  52 ( 3.6A)
 0.79A 5n4tB-5wz4A:
undetectable		 5n4tB-5wz4A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S23,
PUTATIVE

(Trichomonas
vaginalis) 		PF00164
(Ribosom_S12_S23) 		3 HIS X  19
ASN X  22
ALA X  25
 G  2 532 ( 3.9A)
G  2 917 ( 3.6A)
G  2 917 ( 3.1A)
 0.80A 5n4tB-5xyiX:
undetectable		 5n4tB-5xyiX:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axg RAS GUANYL-RELEASING
PROTEIN 4

(Homo sapiens) 		no annotation 3 HIS A  80
ASN A  83
ALA A  87
 None
 0.00A 5n4tB-6axgA:
undetectable		 5n4tB-6axgA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6da0 GLUCOKINASE

(Naegleria
fowleri) 		no annotation 3 HIS A  88
ASN A  91
ALA A  95
 None
 0.30A 5n4tB-6da0A:
undetectable		 5n4tB-6da0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC8

(Saccharomyces
cerevisiae) 		no annotation 3 HIS G  28
ASN G  31
ALA G  35
 None
 0.71A 5n4tB-6f42G:
undetectable		 5n4tB-6f42G:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fks -

(-) 		no annotation 3 HIS A 103
ASN A 106
ALA A 110
 None
 0.52A 5n4tB-6fksA:
undetectable		 5n4tB-6fksA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g9o VOLUME-REGULATED
ANION CHANNEL
SUBUNIT LRRC8A

(Mus musculus) 		no annotation 3 HIS A 104
ASN A 107
ALA A 111
 None
 0.40A 5n4tB-6g9oA:
undetectable		 5n4tB-6g9oA:
undetectable