SIMILAR PATTERNS OF AMINO ACIDS FOR 5MWU_B_ACTB601_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cid T CELL SURFACE
GLYCOPROTEIN CD4

(Rattus
norvegicus) 		PF05790
(C2-set)
PF09191
(CD4-extracel) 		3 THR A 118
PRO A 112
ASP A 113
 None
 0.80A 5mwuB-1cidA:
undetectable		 5mwuB-1cidA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e4o MALTODEXTRIN
PHOSPHORYLASE

(Escherichia
coli) 		PF00343
(Phosphorylase) 		3 THR A 134
PRO A 216
ASP A 203
 None
 0.83A 5mwuB-1e4oA:
1.0		 5mwuB-1e4oA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		3 THR A 187
PRO A 164
ASP A 162
 None
 0.88A 5mwuB-1f1xA:
undetectable		 5mwuB-1f1xA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fh5 MONOCLONAL ANTIBODY
MAK33

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 THR H  88
PRO H  38
ASP H  39
 None
 0.92A 5mwuB-1fh5H:
undetectable		 5mwuB-1fh5H:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fr9 MOLYBDOPTERIN-GUANIN
E DINUCLEOTIDE
BIOSYNTHESIS PROTEIN

(Escherichia
coli) 		PF12804
(NTP_transf_3) 		3 THR A 134
PRO A  99
ASP A 101
 None
 0.72A 5mwuB-1fr9A:
undetectable		 5mwuB-1fr9A:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcw CERULOPLASMIN

(Homo sapiens) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 THR A1024
PRO A 167
ASP A 165
 None
 0.92A 5mwuB-1kcwA:
0.0		 5mwuB-1kcwA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcz BETA-METHYLASPARTASE

(Clostridium
tetanomorphum) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		3 THR A 360
PRO A 333
ASP A 334
 OCS  A 361 ( 3.3A)
None
None
 0.94A 5mwuB-1kczA:
0.0		 5mwuB-1kczA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lcs FELINE LEUKEMIA
VIRUS
RECEPTOR-BINDING
DOMAIN

(Feline leukemia
virus) 		PF00429
(TLV_coat) 		3 THR A 127
PRO A 162
ASP A  42
 None
 0.91A 5mwuB-1lcsA:
undetectable		 5mwuB-1lcsA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nsa PROCARBOXYPEPTIDASE
B

(Sus scrofa) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		3 THR A 245
PRO A 242
ASP A 216
 None
 0.86A 5mwuB-1nsaA:
undetectable		 5mwuB-1nsaA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q8i DNA POLYMERASE II

(Escherichia
coli) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 THR A 102
PRO A  46
ASP A  48
 None
 0.64A 5mwuB-1q8iA:
0.2		 5mwuB-1q8iA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u0j DNA REPLICATION
PROTEIN

(Adeno-associated
dependoparvovirus
A) 		PF01057
(Parvo_NS1) 		3 THR A 321
PRO A 281
ASP A 282
 None
 0.85A 5mwuB-1u0jA:
0.7		 5mwuB-1u0jA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v9n MALATE DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF02615
(Ldh_2) 		3 THR A 149
PRO A 169
ASP A 184
 NDP  A 401 ( 4.2A)
NDP  A 401 (-4.3A)
NDP  A 401 (-2.5A)
 0.72A 5mwuB-1v9nA:
undetectable		 5mwuB-1v9nA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w2w 5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE
5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF01008
(IF-2B)
PF01008
(IF-2B) 		3 THR B 316
PRO B 313
ASP A 147
 None
 0.92A 5mwuB-1w2wB:
undetectable		 5mwuB-1w2wB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0a MALATE/L-LACTATE
DEHYDROGENASE FAMILY
PROTEIN

(Thermus
thermophilus) 		PF02615
(Ldh_2) 		3 THR A 137
PRO A 157
ASP A 172
 None
None
NA  A 403 (-4.6A)
 0.94A 5mwuB-1x0aA:
undetectable		 5mwuB-1x0aA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0u INITIATION FACTOR 2B

(Leishmania
major) 		PF01008
(IF-2B) 		3 THR A 301
PRO A 298
ASP A 152
 None
 0.92A 5mwuB-2a0uA:
undetectable		 5mwuB-2a0uA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ib5 CHROMO PROTEIN

(Epiactis
japonica) 		PF01353
(GFP) 		3 THR A 137
PRO A 131
ASP A  98
 None
 0.93A 5mwuB-2ib5A:
undetectable		 5mwuB-2ib5A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pan GLYOXYLATE
CARBOLIGASE

(Escherichia
coli) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 THR A 132
PRO A 163
ASP A 165
 None
 0.88A 5mwuB-2panA:
undetectable		 5mwuB-2panA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pzk PUTATIVE NUCLEOTIDE
SUGAR EPIMERASE/
DEHYDRATASE

(Bordetella
bronchiseptica) 		PF01370
(Epimerase) 		3 THR A 125
PRO A 129
ASP A 131
 None
 0.66A 5mwuB-2pzkA:
undetectable		 5mwuB-2pzkA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfl INOSITOL-1-MONOPHOSP
HATASE

(Escherichia
coli) 		PF00459
(Inositol_P) 		3 THR A  66
PRO A  85
ASP A  44
 None
 0.89A 5mwuB-2qflA:
1.9		 5mwuB-2qflA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vfk AKAP18 DELTA

(Homo sapiens) 		PF10469
(AKAP7_NLS) 		3 THR A  99
PRO A  97
ASP A 266
 None
 0.79A 5mwuB-2vfkA:
undetectable		 5mwuB-2vfkA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w8s PHOSPHONATE
MONOESTER HYDROLASE

(Paraburkholderia
caryophylli) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 THR A 277
PRO A 245
ASP A 246
 None
 0.83A 5mwuB-2w8sA:
undetectable		 5mwuB-2w8sA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wjv REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF09416
(UPF1_Zn_bind)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 THR A 864
PRO A 494
ASP A 662
 None
SO4  A 990 (-3.8A)
None
 0.77A 5mwuB-2wjvA:
undetectable		 5mwuB-2wjvA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzl ATP-DEPENDENT
HELICASE NAM7

(Saccharomyces
cerevisiae) 		PF09416
(UPF1_Zn_bind)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 THR A 800
PRO A 432
ASP A 598
 None
ALF  A1855 (-3.7A)
None
 0.93A 5mwuB-2xzlA:
undetectable		 5mwuB-2xzlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xzo REGULATOR OF
NONSENSE TRANSCRIPTS
1

(Homo sapiens) 		PF04851
(ResIII)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 THR A 864
PRO A 494
ASP A 662
 None
ALF  A1005 (-3.6A)
None
 0.90A 5mwuB-2xzoA:
undetectable		 5mwuB-2xzoA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yg6 PUTRESCINE OXIDASE

(Rhodococcus
erythropolis) 		PF01593
(Amino_oxidase) 		3 THR A 391
PRO A 265
ASP A 424
 FAD  A 600 ( 4.9A)
FAD  A 600 ( 4.7A)
None
 0.66A 5mwuB-2yg6A:
undetectable		 5mwuB-2yg6A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yr5 PRO-ENZYME OF
L-PHENYLALANINE
OXIDASE

(Pseudomonas sp.
P-501) 		no annotation 3 THR A 613
PRO A 411
ASP A 652
 None
FAD  A 801 (-4.2A)
FAD  A 801 (-3.3A)
 0.73A 5mwuB-2yr5A:
undetectable		 5mwuB-2yr5A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zu6 EUKARYOTIC
INITIATION FACTOR
4A-I

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 THR A 215
PRO A 217
ASP A 219
 None
 0.79A 5mwuB-2zu6A:
undetectable		 5mwuB-2zu6A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zuf ARGINYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00750
(tRNA-synt_1d)
PF03485
(Arg_tRNA_synt_N)
PF05746
(DALR_1) 		3 THR A 540
PRO A  93
ASP A  91
 None
 0.43A 5mwuB-2zufA:
2.0		 5mwuB-2zufA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3akc CYTIDYLATE KINASE

(Thermus
thermophilus) 		PF02224
(Cytidylate_kin) 		3 THR A 143
PRO A  10
ASP A 172
 None
 0.93A 5mwuB-3akcA:
undetectable		 5mwuB-3akcA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 THR A 193
PRO A 415
ASP A 433
 CL  A   7 (-3.2A)
None
None
 0.82A 5mwuB-3bgaA:
undetectable		 5mwuB-3bgaA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d34 SPONDIN-2

(Homo sapiens) 		PF06468
(Spond_N) 		3 THR A 170
PRO A 133
ASP A 166
 None
 0.81A 5mwuB-3d34A:
undetectable		 5mwuB-3d34A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 THR A 169
PRO A 391
ASP A 409
 None
 0.82A 5mwuB-3decA:
undetectable		 5mwuB-3decA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e7f 6-PHOSPHOGLUCONOLACT
ONASE

(Trypanosoma
brucei) 		PF01182
(Glucosamine_iso) 		3 THR A 113
PRO A  80
ASP A  82
 None
 0.78A 5mwuB-3e7fA:
undetectable		 5mwuB-3e7fA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzj POLYNEURIDINE-ALDEHY
DE ESTERASE

(Rauvolfia
serpentina) 		PF00561
(Abhydrolase_1) 		3 THR A 200
PRO A 117
ASP A 116
 None
 0.90A 5mwuB-3gzjA:
undetectable		 5mwuB-3gzjA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhr HUMAN GROWTH HORMONE
RECEPTOR (HGHBP)

(Homo sapiens) 		PF00041
(fn3)
PF09067
(EpoR_lig-bind) 		3 THR B  45
PRO B  41
ASP B 132
 None
 0.86A 5mwuB-3hhrB:
undetectable		 5mwuB-3hhrB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0p MALATE DEHYDROGENASE

(Entamoeba
histolytica) 		PF02615
(Ldh_2) 		3 THR A 145
PRO A 165
ASP A 181
 NAD  A 401 (-4.2A)
NAD  A 401 (-4.1A)
NAD  A 401 (-2.7A)
 0.92A 5mwuB-3i0pA:
undetectable		 5mwuB-3i0pA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ihv SUSD HOMOLOG

(Bacteroides
thetaiotaomicron) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 THR A 203
PRO A 278
ASP A 277
 None
 0.94A 5mwuB-3ihvA:
undetectable		 5mwuB-3ihvA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4r A-KINASE ANCHOR
PROTEIN 18

(Homo sapiens) 		PF10469
(AKAP7_NLS)
PF10470
(AKAP7_RIRII_bdg) 		3 THR A  99
PRO A  97
ASP A 266
 None
 0.76A 5mwuB-3j4rA:
undetectable		 5mwuB-3j4rA:
23.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m9v FAD-DEPENDENT
OXIDOREDUCTASE

(Actinomadura
kijaniata) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 THR A  96
PRO A  50
ASP A  52
 None
 0.92A 5mwuB-3m9vA:
undetectable		 5mwuB-3m9vA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mcz O-METHYLTRANSFERASE

(Burkholderia
thailandensis) 		PF00891
(Methyltransf_2)
PF16864
(Dimerisation2) 		3 THR A 286
PRO A 294
ASP A  15
 None
 0.93A 5mwuB-3mczA:
undetectable		 5mwuB-3mczA:
21.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN

(Escherichia
coli) 		PF00496
(SBP_bac_5) 		3 THR A 203
PRO A 225
ASP A 227
 None
 0.46A 5mwuB-3mzbA:
59.7		 5mwuB-3mzbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2c PUTATIVE GLYCOSYL
HYDROLASE

(Bacteroides
ovatus) 		PF06824
(Glyco_hydro_125) 		3 THR A  79
PRO A  83
ASP A  87
 None
 0.76A 5mwuB-3p2cA:
undetectable		 5mwuB-3p2cA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Mycobacteroides
abscessus) 		PF01259
(SAICAR_synt) 		3 THR A 181
PRO A 138
ASP A 136
 THR  A 181 ( 0.8A)
PRO  A 138 ( 1.1A)
ASP  A 136 ( 0.6A)
 0.91A 5mwuB-3r9rA:
undetectable		 5mwuB-3r9rA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rc2 SUGAR
3-KETOREDUCTASE

(Actinomadura
kijaniata) 		PF01408
(GFO_IDH_MocA) 		3 THR A 106
PRO A 103
ASP A 182
 None
NAP  A 336 ( 4.8A)
NAP  A 336 (-3.5A)
 0.87A 5mwuB-3rc2A:
undetectable		 5mwuB-3rc2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rha PUTRESCINE OXIDASE

(Paenarthrobacter
aurescens) 		PF01593
(Amino_oxidase) 		3 THR A 392
PRO A 266
ASP A 425
 FDA  A 483 ( 4.8A)
FDA  A 483 ( 4.5A)
None
 0.59A 5mwuB-3rhaA:
undetectable		 5mwuB-3rhaA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ttk POLYAMINE TRANSPORT
PROTEIN

(Pseudomonas
aeruginosa) 		PF13416
(SBP_bac_8) 		3 THR A 357
PRO A 181
ASP A 179
 None
 0.60A 5mwuB-3ttkA:
3.5		 5mwuB-3ttkA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uoe DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02615
(Ldh_2) 		3 THR A  64
PRO A  22
ASP A  24
 None
 0.75A 5mwuB-3uoeA:
undetectable		 5mwuB-3uoeA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3s 6-PHOSPHOFRUCTOKINAS
E

(Bacillus
subtilis) 		PF00365
(PFK) 		3 THR A 302
PRO A 131
ASP A 103
 None
 0.90A 5mwuB-4a3sA:
undetectable		 5mwuB-4a3sA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aqq L2 PROTEIN III
(PENTON BASE)

(Human
mastadenovirus
B) 		PF01686
(Adeno_Penton_B) 		3 THR A 221
PRO A 481
ASP A 191
 None
 0.88A 5mwuB-4aqqA:
undetectable		 5mwuB-4aqqA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4at0 3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E

(Rhodococcus
jostii) 		PF00890
(FAD_binding_2) 		3 THR A 351
PRO A 139
ASP A 142
 None
 0.83A 5mwuB-4at0A:
undetectable		 5mwuB-4at0A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b29 DIMETHYLSULFONIOPROP
IONATE LYASE

(Roseovarius
nubinhibens) 		PF16867
(DMSP_lyase) 		3 THR A 174
PRO A 120
ASP A  53
 None
PO4  A1200 (-4.4A)
PO4  A1200 (-3.5A)
 0.91A 5mwuB-4b29A:
undetectable		 5mwuB-4b29A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b3g DNA-BINDING PROTEIN
SMUBP-2

(Homo sapiens) 		PF13086
(AAA_11)
PF13087
(AAA_12) 		3 THR A 602
PRO A 216
ASP A 400
 None
 0.84A 5mwuB-4b3gA:
undetectable		 5mwuB-4b3gA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b46 CELL DIVISION
PROTEIN FTSZ

(Haloferax
volcanii) 		PF00091
(Tubulin) 		3 THR A 147
PRO A 138
ASP A 168
 None
GDP  A1368 (-4.2A)
None
 0.59A 5mwuB-4b46A:
undetectable		 5mwuB-4b46A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3h DNA-DIRECTED RNA
POLYMERASE I SUBUNIT
RPA190

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 THR A 318
PRO A  84
ASP A 358
 None
 0.88A 5mwuB-4c3hA:
undetectable		 5mwuB-4c3hA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ef1 PHEROMONE
COB1/LIPOPROTEIN,
YAEC FAMILY

(Enterococcus
faecalis) 		PF03180
(Lipoprotein_9) 		3 THR A  65
PRO A  38
ASP A 208
 None
 0.92A 5mwuB-4ef1A:
3.8		 5mwuB-4ef1A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0q RESTRICTION
ENDONUCLEASE

(Mycobacterium
sp. JLS) 		PF04471
(Mrr_cat) 		3 THR A  98
PRO A 195
ASP A 194
 None
 0.93A 5mwuB-4f0qA:
undetectable		 5mwuB-4f0qA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hdt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE

(Mycolicibacterium
thermoresistibile) 		PF16113
(ECH_2) 		3 THR A 323
PRO A 263
ASP A 301
 None
 0.93A 5mwuB-4hdtA:
undetectable		 5mwuB-4hdtA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jgt 3-MERCAPTOPYRUVATE
SULFURTRANSFERASE

(Homo sapiens) 		PF00581
(Rhodanese) 		3 THR A 186
PRO A 212
ASP A 215
 None
 0.86A 5mwuB-4jgtA:
undetectable		 5mwuB-4jgtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkl BETA-GLUCURONIDASE

(Streptococcus
agalactiae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 THR A 105
PRO A 331
ASP A 349
 None
 0.94A 5mwuB-4jklA:
undetectable		 5mwuB-4jklA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jkm BETA-GLUCURONIDASE

(Clostridium
perfringens) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 THR A 111
PRO A 334
ASP A 352
 None
 0.93A 5mwuB-4jkmA:
undetectable		 5mwuB-4jkmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k1x NADPH:FERREDOXIN
REDUCTASE

(Rhodobacter
capsulatus) 		PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		3 THR A  41
PRO A 106
ASP A  17
 None
 0.81A 5mwuB-4k1xA:
undetectable		 5mwuB-4k1xA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kpu ELECTRON TRANSFER
FLAVOPROTEIN ALPHA
SUBUNIT
ELECTRON TRANSFER
FLAVOPROTEIN
ALPHA/BETA-SUBUNIT

(Acidaminococcus
fermentans;
Acidaminococcus
fermentans) 		PF00766
(ETF_alpha)
PF01012
(ETF)
PF01012
(ETF) 		3 THR A 125
PRO B 220
ASP B  93
 None
None
FAD  B 301 (-4.0A)
 0.93A 5mwuB-4kpuA:
undetectable		 5mwuB-4kpuA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kt1 LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4

(Homo sapiens) 		PF01462
(LRRNT)
PF13516
(LRR_6)
PF13855
(LRR_8) 		3 THR A 119
PRO A 145
ASP A 147
 None
 0.87A 5mwuB-4kt1A:
undetectable		 5mwuB-4kt1A:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mph D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
FAMILY PROTEIN

(Bacillus
anthracis) 		PF02557
(VanY) 		3 THR A 162
PRO A  77
ASP A  79
 None
 0.76A 5mwuB-4mphA:
undetectable		 5mwuB-4mphA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oet PUTATIVE PEPTIDE
ABC-TRANSPORT SYSTEM
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN

(Campylobacter
jejuni) 		PF00496
(SBP_bac_5) 		3 THR A 431
PRO A 127
ASP A 389
 None
None
GOL  A 506 (-4.6A)
 0.80A 5mwuB-4oetA:
35.9		 5mwuB-4oetA:
28.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ox3 PUTATIVE
CARBOXYPEPTIDASE
YODJ

(Bacillus
subtilis) 		PF02557
(VanY) 		3 THR A 187
PRO A 102
ASP A 104
 None
 0.84A 5mwuB-4ox3A:
undetectable		 5mwuB-4ox3A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p08 COCAINE ESTERASE

(Rhodococcus sp.
MB1) 		PF02129
(Peptidase_S15)
PF08530
(PepX_C) 		3 THR A 349
PRO A 354
ASP A 355
 None
 0.90A 5mwuB-4p08A:
undetectable		 5mwuB-4p08A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qt8 MACROPHAGE-STIMULATI
NG PROTEIN RECEPTOR

(Homo sapiens) 		no annotation 3 THR B 153
PRO B  83
ASP B  84
 None
 0.73A 5mwuB-4qt8B:
undetectable		 5mwuB-4qt8B:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxf LEUCINE-RICH
REPEAT-CONTAINING
G-PROTEIN COUPLED
RECEPTOR 4, VARIABLE
LYMPHOCYTE RECEPTOR
B

(Eptatretus
burgeri;
Homo sapiens) 		PF01462
(LRRNT)
PF11921
(DUF3439)
PF13855
(LRR_8) 		3 THR A 119
PRO A 145
ASP A 147
 None
 0.91A 5mwuB-4qxfA:
undetectable		 5mwuB-4qxfA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rft COAT PROTEIN

(Redspotted
grouper nervous
necrosis virus) 		no annotation 3 THR A 169
PRO A  86
ASP A  87
 None
 0.94A 5mwuB-4rftA:
undetectable		 5mwuB-4rftA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s1p UNCHARACTERIZED
PROTEIN

(Slackia
heliotrinireducens) 		PF13472
(Lipase_GDSL_2) 		3 THR A  12
PRO A  17
ASP A  18
 None
 0.91A 5mwuB-4s1pA:
undetectable		 5mwuB-4s1pA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y18 BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN

(Homo sapiens) 		PF00533
(BRCT) 		3 THR A1834
PRO A1812
ASP A1813
 None
 0.91A 5mwuB-4y18A:
undetectable		 5mwuB-4y18A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8r METHYL-COENZYME M
REDUCTASE II SUBUNIT
ALPHA

(Methanothermobacter
marburgensis) 		PF02249
(MCR_alpha)
PF02745
(MCR_alpha_N) 		3 THR A  43
PRO A  61
ASP A  62
 None
 0.94A 5mwuB-5a8rA:
undetectable		 5mwuB-5a8rA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnn CAPSID PROTEIN VP2

(Enterovirus D) 		PF00073
(Rhv) 		3 THR B  76
PRO B 158
ASP B 162
 None
 0.85A 5mwuB-5bnnB:
undetectable		 5mwuB-5bnnB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5chc DMSO REDUCTASE
FAMILY TYPE II
ENZYME,
MOLYBDOPTERIN
SUBUNIT

(Azospira oryzae) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 THR A 249
PRO A 750
ASP A 752
 None
 0.92A 5mwuB-5chcA:
undetectable		 5mwuB-5chcA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d1r RV1816
TRANSCRIPTIONAL
REGULATOR

(Mycobacterium
tuberculosis) 		PF00440
(TetR_N) 		3 THR A  65
PRO A 127
ASP A 129
 None
 0.90A 5mwuB-5d1rA:
undetectable		 5mwuB-5d1rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbj FADH2-DEPENDENT
HALOGENASE PLTA

(Pseudomonas
protegens) 		no annotation 3 THR E 244
PRO E  71
ASP E 224
 None
 0.93A 5mwuB-5dbjE:
undetectable		 5mwuB-5dbjE:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dmy BETA-GALACTOSIDASE

(Bifidobacterium
bifidum) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		3 THR A 429
PRO A 136
ASP A 112
 None
 0.66A 5mwuB-5dmyA:
undetectable		 5mwuB-5dmyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eaw DNA REPLICATION
ATP-DEPENDENT
HELICASE/NUCLEASE
DNA2

(Mus musculus) 		PF08696
(Dna2)
PF13086
(AAA_11)
PF13087
(AAA_12) 		3 THR A1007
PRO A 651
ASP A 788
 None
 0.85A 5mwuB-5eawA:
0.3		 5mwuB-5eawA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exe OXALATE
OXIDOREDUCTASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF02775
(TPP_enzyme_C) 		3 THR C 194
PRO C 179
ASP C 177
 None
 0.94A 5mwuB-5exeC:
undetectable		 5mwuB-5exeC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fur TRANSCRIPTION
INITIATION FACTOR
TFIID SUBUNIT 2

(Homo sapiens) 		no annotation 3 THR I 567
PRO I 632
ASP I 633
 None
 0.93A 5mwuB-5furI:
undetectable		 5mwuB-5furI:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j44 SERINE PROTEASE SEPA
AUTOTRANSPORTER

(Shigella
flexneri) 		PF02395
(Peptidase_S6) 		3 THR A 620
PRO A 612
ASP A 589
 None
 0.93A 5mwuB-5j44A:
undetectable		 5mwuB-5j44A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3q EUKARYOTIC
TRANSLATION
INITIATION FACTOR 6

(Chaetomium
thermophilum) 		PF01912
(eIF-6) 		3 THR A 141
PRO A 119
ASP A 120
 None
 0.77A 5mwuB-5m3qA:
undetectable		 5mwuB-5m3qA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzn HELICASE
SEN1,HELICASE SEN1

(Saccharomyces
cerevisiae) 		PF13086
(AAA_11)
PF13087
(AAA_12) 		3 THR A1819
PRO A1359
ASP A1616
 None
PEG  A2057 ( 3.5A)
None
 0.85A 5mwuB-5mznA:
undetectable		 5mwuB-5mznA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ol8 TRANSCRIPTION
ELONGATION FACTOR,
MITOCHONDRIAL

(Homo sapiens) 		no annotation 3 THR A 190
PRO A 318
ASP A 320
 None
 0.86A 5mwuB-5ol8A:
undetectable		 5mwuB-5ol8A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t98 GLYCOSIDE HYDROLASE

(Bacteroides
uniformis) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF16355
(DUF4982) 		3 THR A 156
PRO A 376
ASP A 394
 None
 0.85A 5mwuB-5t98A:
undetectable		 5mwuB-5t98A:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5urb METHIONINE--TRNA
LIGASE

(Acinetobacter
baumannii) 		PF08264
(Anticodon_1)
PF09334
(tRNA-synt_1g) 		3 THR A 104
PRO A 241
ASP A 242
 None
 0.84A 5mwuB-5urbA:
undetectable		 5mwuB-5urbA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wwp ORF1AB

(Middle East
respiratory
syndrome-related
coronavirus) 		no annotation 3 THR B 566
PRO B 284
ASP B 401
 None
SO4  B 604 (-4.5A)
None
 0.84A 5mwuB-5wwpB:
undetectable		 5mwuB-5wwpB:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x3e KINESIN-LIKE PROTEIN

(Caenorhabditis
elegans) 		PF00225
(Kinesin) 		3 THR A  41
PRO A 407
ASP A 408
 None
 0.89A 5mwuB-5x3eA:
undetectable		 5mwuB-5x3eA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmi VACUOLAR PROTEIN
SORTING-ASSOCIATED
PROTEIN 4

(Saccharomyces
cerevisiae) 		PF00004
(AAA)
PF04212
(MIT) 		3 THR A 374
PRO A 399
ASP A 405
 None
 0.89A 5mwuB-5xmiA:
undetectable		 5mwuB-5xmiA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y51 -

(-) 		no annotation 3 THR A  39
PRO A  60
ASP A  63
 None
 0.91A 5mwuB-5y51A:
undetectable		 5mwuB-5y51A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yal ESTERASE

(Streptomyces
cinnamoneus) 		no annotation 3 THR A 270
PRO A 275
ASP A 279
 None
 0.70A 5mwuB-5yalA:
undetectable		 5mwuB-5yalA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yhp COLD ACTIVE PROLINE
IMINOPEPTIDASE

(Glaciozyma
antarctica) 		no annotation 3 THR A  13
PRO A  10
ASP A  50
 None
 0.55A 5mwuB-5yhpA:
undetectable		 5mwuB-5yhpA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yt0 PROBABLE TRANSLATION
INITIATION FACTOR
IF-2

(Aeropyrum
pernix) 		no annotation 3 THR A  50
PRO A  59
ASP A  61
 None
 0.75A 5mwuB-5yt0A:
undetectable		 5mwuB-5yt0A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zu5 ALGINATE LYASE

(Vibrio
splendidus) 		no annotation 3 THR A 281
PRO A 244
ASP A 246
 None
 0.84A 5mwuB-5zu5A:
undetectable		 5mwuB-5zu5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3b APRA
METHYLTRANSFERASE 1

(Moorea
bouillonii) 		no annotation 3 THR A 436
PRO A 603
ASP A 467
 None
 0.91A 5mwuB-6b3bA:
undetectable		 5mwuB-6b3bA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b6l GLYCOSYL HYDROLASE
FAMILY 2, SUGAR
BINDING DOMAIN
PROTEIN

(Bacteroides
cellulosilyticus) 		no annotation 3 THR A 139
PRO A 360
ASP A 378
 None
 0.84A 5mwuB-6b6lA:
undetectable		 5mwuB-6b6lA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6enz ACIDIC AMINO ACID
DECARBOXYLASE GADL1

(Mus musculus) 		no annotation 3 THR A  46
PRO A  96
ASP A 487
 None
 0.64A 5mwuB-6enzA:
undetectable		 5mwuB-6enzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f72 MTVAO615

(Thermothelomyces
thermophila) 		no annotation 3 THR A 424
PRO A 331
ASP A 332
 None
 0.91A 5mwuB-6f72A:
undetectable		 5mwuB-6f72A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ffl MALTOSE/MALTODEXTRIN
TRANSPORT PERMEASE
HOMOLOGUE

(Bdellovibrio
bacteriovorus) 		no annotation 3 THR A  42
PRO A  65
ASP A  67
 GLC  A 409 (-4.2A)
GLC  A 407 (-4.0A)
GLC  A 407 (-2.9A)
 0.88A 5mwuB-6fflA:
undetectable		 5mwuB-6fflA:
undetectable