SIMILAR PATTERNS OF AMINO ACIDS FOR 5MUR_B_PFLB407
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f9a | HYPOTHETICAL PROTEINMJ0541 (Methanocaldococcusjannaschii) |
PF01467(CTP_transf_like) | 4 | TYR A 68ILE A 31ILE A 32ILE A 23 | None | 0.94A | 5murB-1f9aA:undetectable | 5murB-1f9aA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyb | NICOTINAMIDEMONONUCLEOTIDEADENYLYLTRANSFERASE (Methanothermobacterthermautotrophicus) |
PF01467(CTP_transf_like) | 4 | TYR A 74ILE A 34ILE A 35ILE A 26 | None | 0.91A | 5murB-1hybA:undetectable | 5murB-1hybA:20.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1j7x | INTERPHOTORECEPTORRETINOID-BINDINGPROTEIN (Xenopus laevis) |
PF03572(Peptidase_S41)PF11918(Peptidase_S41_N) | 4 | TYR A 207ILE A 145ILE A 146ILE A 138 | None | 0.93A | 5murB-1j7xA:undetectable | 5murB-1j7xA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mgw | GUANYL-SPECIFICRIBONUCLEASE SA3 (Kitasatosporaaureofaciens) |
PF00545(Ribonuclease) | 4 | TYR A 83ILE A 74ILE A 73ILE A 25 | NoneNoneNone LI A 901 ( 4.4A) | 0.93A | 5murB-1mgwA:undetectable | 5murB-1mgwA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mqq | ALPHA-D-GLUCURONIDASE (Geobacillusstearothermophilus) |
PF03648(Glyco_hydro_67N)PF07477(Glyco_hydro_67C)PF07488(Glyco_hydro_67M) | 4 | TYR A 105ILE A 107ILE A 106ILE A 136 | GOL A 756 ( 3.8A)NoneNoneNone | 0.91A | 5murB-1mqqA:4.1 | 5murB-1mqqA:8.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pm2 | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1BETA CHAIN (Escherichiacoli) |
PF00268(Ribonuc_red_sm) | 4 | TYR A 122ILE A 125ILE A 126ILE A 74 | None | 0.63A | 5murB-1pm2A:2.7 | 5murB-1pm2A:13.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qwr | MANNOSE-6-PHOSPHATEISOMERASE (Bacillussubtilis) |
PF01238(PMI_typeI) | 4 | TYR A 131ILE A 157ILE A 129ILE A 120 | None | 0.89A | 5murB-1qwrA:0.0 | 5murB-1qwrA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sa3 | TYPE II RESTRICTIONENZYME MSPI (Moraxella sp.) |
PF09208(Endonuc-MspI) | 4 | TYR A 37ILE A 41ILE A 38ILE A 219 | None | 0.94A | 5murB-1sa3A:undetectable | 5murB-1sa3A:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tdj | BIOSYNTHETICTHREONINE DEAMINASE (Escherichiacoli) |
PF00291(PALP)PF00585(Thr_dehydrat_C) | 4 | TYR A 299ILE A 305ILE A 300ILE A 48 | None | 0.92A | 5murB-1tdjA:0.0 | 5murB-1tdjA:10.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vjx | PUTATIVEFERRITIN-LIKEDIIRON-CARBOXYLATEPROTEIN TM1526 (Thermotogamaritima) |
PF02915(Rubrerythrin) | 4 | PRO A 76ILE A 95THR A 78ILE A 81 | None | 0.90A | 5murB-1vjxA:4.0 | 5murB-1vjxA:25.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y60 | FORMALDEHYDE-ACTIVATING ENZYME FAE (Methylobacteriumextorquens) |
PF08714(Fae) | 4 | PRO A 64ILE A 142ILE A 27THR A 66 | None | 0.81A | 5murB-1y60A:undetectable | 5murB-1y60A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygg | PHOSPHOENOLPYRUVATECARBOXYKINASE (Actinobacillussuccinogenes) |
PF01293(PEPCK_ATP) | 4 | ILE A 459ILE A 458THR A 441ILE A 450 | None | 0.91A | 5murB-1yggA:undetectable | 5murB-1yggA:10.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ygp | YEAST GLYCOGENPHOSPHORYLASE (Saccharomycescerevisiae) |
PF00343(Phosphorylase) | 4 | TYR A 587ILE A 584ILE A 583ILE A 623 | None | 0.88A | 5murB-1ygpA:undetectable | 5murB-1ygpA:6.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aeu | HYPOTHETICAL PROTEINMJ0158 (Methanocaldococcusjannaschii) |
PF03841(SelA) | 4 | TYR A 31ILE A 328ILE A 329ILE A 17 | None | 0.94A | 5murB-2aeuA:undetectable | 5murB-2aeuA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2an2 | P332G A333S DOUBLEMUTANT OF NITRICOXIDE SYNTHASE FROMBACILLUS SUBTILIS (Bacillussubtilis) |
PF02898(NO_synthase) | 4 | ILE A 127ILE A 213THR A 97ILE A 102 | None | 0.88A | 5murB-2an2A:undetectable | 5murB-2an2A:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bih | NITRATE REDUCTASE[NADPH] (Ogataea angusta) |
PF00174(Oxidored_molyb)PF03404(Mo-co_dimer) | 4 | PRO A 449TYR A 433MET A 420ILE A 469 | None | 0.89A | 5murB-2bihA:undetectable | 5murB-2bihA:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmb | FOLIC ACID SYNTHESISPROTEIN FOL1 (Saccharomycescerevisiae) |
PF00809(Pterin_bind)PF01288(HPPK) | 4 | PRO A 756ILE A 771ILE A 774ILE A 728 | None | 0.89A | 5murB-2bmbA:undetectable | 5murB-2bmbA:10.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c11 | MEMBRANE COPPERAMINE OXIDASE (Homo sapiens) |
PF01179(Cu_amine_oxid)PF02727(Cu_amine_oxidN2)PF02728(Cu_amine_oxidN3) | 4 | ILE A 179ILE A 183MET A 182ILE A 261 | None | 0.82A | 5murB-2c11A:undetectable | 5murB-2c11A:7.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c5a | GDP-MANNOSE-3',5'-EPIMERASE (Arabidopsisthaliana) |
PF01370(Epimerase) | 4 | PRO A 321ILE A 269THR A 246ILE A 204 | NoneNoneNoneNAD A1378 (-4.3A) | 0.93A | 5murB-2c5aA:undetectable | 5murB-2c5aA:11.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cry | KIN OF IRRE-LIKEPROTEIN 3 (Homo sapiens) |
PF13927(Ig_3) | 4 | ILE A 106ILE A 107THR A 104ILE A 17 | None | 0.91A | 5murB-2cryA:undetectable | 5murB-2cryA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gzl | 2-C-METHYL-D-ERYTHRITOL2,4-CYCLODIPHOSPHATESYNTHASE (Escherichiacoli) |
PF02542(YgbB) | 4 | TYR A 27ILE A 18ILE A 25ILE A 98 | None | 0.91A | 5murB-2gzlA:undetectable | 5murB-2gzlA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hpg | ABC TRANSPORTER,PERIPLASMICSUBSTRATE-BINDINGPROTEIN (Thermotogamaritima) |
PF03480(DctP) | 4 | TYR A 260ILE A 263ILE A 264ILE A 59 | None | 0.73A | 5murB-2hpgA:undetectable | 5murB-2hpgA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2i4c | BICARBONATETRANSPORTER (Synechocystissp. PCC 6803) |
PF13379(NMT1_2) | 4 | PRO A 224ILE A 68ILE A 66THR A 192 | NoneBCT A 460 (-4.5A)NoneBCT A 460 (-2.7A) | 0.91A | 5murB-2i4cA:undetectable | 5murB-2i4cA:13.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ocd | L-ASPARAGINASE I (Vibrio cholerae) |
PF00710(Asparaginase) | 4 | TYR A 7ILE A 8ILE A 6ILE A 113 | None | 0.93A | 5murB-2ocdA:undetectable | 5murB-2ocdA:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vk9 | ALPHA-TOXIN (Clostridiumnovyi) |
PF12918(TcdB_N)PF12919(TcdA_TcdB) | 4 | TYR A 459ILE A 416ILE A 456ILE A 411 | None | 0.92A | 5murB-2vk9A:4.5 | 5murB-2vk9A:9.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsb | HYALURONOGLUCOSAMINIDASE (Oceanicolagranulosus) |
PF07555(NAGidase) | 5 | ILE A 266ILE A 26MET A 31THR A 253ILE A 252 | None | 1.43A | 5murB-2xsbA:3.4 | 5murB-2xsbA:11.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsb | HYALURONOGLUCOSAMINIDASE (Oceanicolagranulosus) |
PF07555(NAGidase) | 5 | PRO A 255ILE A 266MET A 31THR A 253ILE A 252 | None | 1.14A | 5murB-2xsbA:3.4 | 5murB-2xsbA:11.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xtl | CELL WALL SURFACEANCHOR FAMILYPROTEIN (Streptococcusagalactiae) |
PF16569(GramPos_pilinBB)PF16570(GramPos_pilinD3) | 4 | PRO A 195TYR A 331THR A 232ILE A 305 | None | 0.80A | 5murB-2xtlA:3.5 | 5murB-2xtlA:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yqe | JUMONJI/ARIDDOMAIN-CONTAININGPROTEIN 1D (Homo sapiens) |
PF01388(ARID) | 4 | TYR A 164ILE A 161ILE A 160ILE A 102 | None | 0.87A | 5murB-2yqeA:undetectable | 5murB-2yqeA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a21 | PUTATIVE SECRETEDALPHA-GALACTOSIDASE (Streptomycesavermitilis) |
PF00652(Ricin_B_lectin)PF16499(Melibiase_2) | 4 | ILE A 139ILE A 97THR A 127ILE A 130 | None | 0.71A | 5murB-3a21A:undetectable | 5murB-3a21A:8.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b7f | GLYCOSYL HYDROLASE,BNR REPEAT (Cupriaviduspinatubonensis) |
no annotation | 4 | TYR A 247ILE A 267ILE A 254THR A 317 | None | 0.87A | 5murB-3b7fA:undetectable | 5murB-3b7fA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cg3 | UPF0100 PROTEINPH0151 (Pyrococcushorikoshii) |
PF13531(SBP_bac_11) | 4 | TYR A 195MET A 163THR A 273ILE A 274 | None | 0.94A | 5murB-3cg3A:undetectable | 5murB-3cg3A:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cia | COLD-ACTIVEAMINOPEPTIDASE (Colwelliapsychrerythraea) |
PF01433(Peptidase_M1)PF09127(Leuk-A4-hydro_C) | 4 | PRO A 179TYR A 140ILE A 95ILE A 127 | None | 0.87A | 5murB-3ciaA:3.9 | 5murB-3ciaA:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkx | REPLICATION PROTEINREPB (Streptococcusagalactiae) |
PF01719(Rep_2) | 4 | TYR A 56ILE A 35MET A 33ILE A 75 | None | 0.84A | 5murB-3dkxA:undetectable | 5murB-3dkxA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f9t | L-TYROSINEDECARBOXYLASE MFNA (Methanocaldococcusjannaschii) |
PF00282(Pyridoxal_deC) | 4 | TYR A 202ILE A 203ILE A 201ILE A 126 | None | 0.93A | 5murB-3f9tA:undetectable | 5murB-3f9tA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h9m | P-AMINOBENZOATESYNTHETASE,COMPONENT I (Cytophagahutchinsonii) |
PF00425(Chorismate_bind) | 4 | TYR A 186ILE A 401ILE A 184ILE A 175 | None | 0.92A | 5murB-3h9mA:undetectable | 5murB-3h9mA:10.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iv3 | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcusmutans) |
PF01791(DeoC) | 4 | PRO A 105TYR A 145ILE A 149ILE A 146 | NoneEDO A 336 (-4.1A)NoneNone | 0.91A | 5murB-3iv3A:undetectable | 5murB-3iv3A:12.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jrk | TAGATOSE1,6-DIPHOSPHATEALDOLASE 2 (Streptococcuspyogenes) |
PF01791(DeoC) | 4 | PRO A 101TYR A 141ILE A 145ILE A 142 | None | 0.89A | 5murB-3jrkA:undetectable | 5murB-3jrkA:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jv3 | INTERSECTIN-1 (Mus musculus) |
PF00621(RhoGEF)PF14604(SH3_9) | 4 | TYR A1378ILE A1381ILE A1382ILE A1308 | None | 0.94A | 5murB-3jv3A:4.1 | 5murB-3jv3A:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kao | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Staphylococcusaureus) |
PF01791(DeoC) | 4 | PRO A 105TYR A 145ILE A 149ILE A 146 | GOL A 332 (-4.6A)NoneNoneNone | 0.90A | 5murB-3kaoA:undetectable | 5murB-3kaoA:11.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3keh | GLUCOCEREBROSIDASE (Homo sapiens) |
PF02055(Glyco_hydro_30)PF17189(Glyco_hydro_30C) | 4 | TYR A 412ILE A 403ILE A 402ILE A 93 | None | 0.91A | 5murB-3kehA:undetectable | 5murB-3kehA:10.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lcm | PUTATIVEOXIDOREDUCTASE (Streptococcusmutans) |
PF02525(Flavodoxin_2) | 4 | ILE A 78ILE A 125THR A 185ILE A 184 | None | 0.86A | 5murB-3lcmA:undetectable | 5murB-3lcmA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3myo | TAGATOSE1,6-DIPHOSPHATEALDOLASE 1 (Streptococcuspyogenes) |
PF01791(DeoC) | 4 | PRO A 104TYR A 144ILE A 148ILE A 145 | None | 0.88A | 5murB-3myoA:undetectable | 5murB-3myoA:15.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q87 | N6 ADENINE SPECIFICDNA METHYLASE (Encephalitozooncuniculi) |
PF05175(MTS) | 4 | PRO B 129TYR B 157ILE B 145ILE B 159 | None | 0.87A | 5murB-3q87B:undetectable | 5murB-3q87B:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qth | UNCHARACTERIZEDPROTEIN (Colwelliapsychrerythraea) |
PF09351(DUF1993) | 4 | PRO A 104TYR A 8ILE A 9ILE A 5 | None | 0.91A | 5murB-3qthA:2.3 | 5murB-3qthA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4u | PHND, SUBUNIT OFALKYLPHOSPHONATE ABCTRANSPORTER (Escherichiacoli) |
PF12974(Phosphonate-bd) | 4 | TYR A 47ILE A 50ILE A 51MET A 54 | None | 0.94A | 5murB-3s4uA:2.5 | 5murB-3s4uA:11.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3upu | ATP-DEPENDENT DNAHELICASE DDA (Escherichiavirus T4) |
PF13604(AAA_30) | 4 | PRO A 104ILE A 84THR A 131ILE A 132 | None | 0.82A | 5murB-3upuA:undetectable | 5murB-3upuA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2g | 3-OXOACYL-[ACYL-CARRIER-PROTEIN]REDUCTASE (Sinorhizobiummeliloti) |
PF13561(adh_short_C2) | 4 | ILE A 96ILE A 100THR A 61ILE A 86 | None | 0.76A | 5murB-3v2gA:undetectable | 5murB-3v2gA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vbj | GALACTOSIDEO-ACETYLTRANSFERASE (Bacillus cereus) |
PF00132(Hexapep) | 4 | TYR A 90ILE A 131ILE A 132ILE A 83 | None | 0.87A | 5murB-3vbjA:undetectable | 5murB-3vbjA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wky | PROPHENOLOXIDASE B (Marsupenaeusjaponicus) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | ILE A 423ILE A 538MET A 501ILE A 545 | None | 0.93A | 5murB-3wkyA:undetectable | 5murB-3wkyA:10.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zm8 | GH26ENDO-BETA-1,4-MANNANASE (Podosporaanserina) |
PF02156(Glyco_hydro_26)PF16990(CBM_35) | 4 | TYR A 65ILE A 63ILE A 122THR A 74 | None | 0.92A | 5murB-3zm8A:undetectable | 5murB-3zm8A:12.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bc7 | ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE,PEROXISOMAL (Cavia porcellus) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 4 | ILE A 83ILE A 82THR A 283ILE A 282 | None | 0.91A | 5murB-4bc7A:undetectable | 5murB-4bc7A:9.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cgu | PROTEIN INTERACTINGWITH HSP90 1 (Saccharomycescerevisiae) |
no annotation | 4 | PRO B 299ILE B 329ILE B 342ILE B 316 | PRO B 299 ( 1.1A)ILE B 329 ( 0.7A)ILE B 342 ( 0.6A)ILE B 316 ( 0.7A) | 0.94A | 5murB-4cguB:undetectable | 5murB-4cguB:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d70 | SORTASE FAMILYPROTEIN (Clostridiumperfringens) |
PF04203(Sortase) | 4 | ILE A 168ILE A 106MET A 166ILE A 132 | None | 0.88A | 5murB-4d70A:undetectable | 5murB-4d70A:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dyk | AMIDOHYDROLASE (Pseudomonasaeruginosa) |
PF01979(Amidohydro_1) | 4 | TYR A 133ILE A 110ILE A 139ILE A 118 | None | 0.89A | 5murB-4dykA:undetectable | 5murB-4dykA:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ihq | FLAI ATPASE (Sulfolobusacidocaldarius) |
PF00437(T2SSE) | 4 | TYR A 494ILE A 495THR A 232ILE A 231 | None | 0.93A | 5murB-4ihqA:undetectable | 5murB-4ihqA:9.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpu | ELECTRON TRANSFERFLAVOPROTEIN ALPHASUBUNIT (Acidaminococcusfermentans) |
PF00766(ETF_alpha)PF01012(ETF) | 4 | TYR A 18ILE A 106MET A 166ILE A 96 | None | 0.82A | 5murB-4kpuA:undetectable | 5murB-4kpuA:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lr4 | HYPOTHETICAL PROTEIN ([Eubacterium]rectale) |
no annotation | 4 | TYR A 185ILE A 176ILE A 184ILE A 220 | None | 0.94A | 5murB-4lr4A:undetectable | 5murB-4lr4A:9.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m8j | L-CARNITINE/GAMMA-BUTYROBETAINEANTIPORTER (Proteusmirabilis) |
PF02028(BCCT) | 4 | ILE A 235ILE A 236THR A 419ILE A 423 | None | 0.61A | 5murB-4m8jA:2.4 | 5murB-4m8jA:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mqb | THYMIDYLATE KINASE (Staphylococcusaureus) |
PF02223(Thymidylate_kin) | 4 | TYR A 167ILE A 170ILE A 171THR A 128 | None | 0.93A | 5murB-4mqbA:undetectable | 5murB-4mqbA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n6k | TRAP DICARBOXYLATETRANSPORTER-DCTPSUBUNIT (Desulfovibriosalexigens) |
PF03480(DctP) | 4 | TYR A 258ILE A 261ILE A 262ILE A 66 | None | 0.71A | 5murB-4n6kA:undetectable | 5murB-4n6kA:15.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o87 | N-TAGGED NUCLEASE (Millerozymaacaciae) |
no annotation | 5 | PRO A 3TYR A 83ILE A 84ILE A 80THR A 5 | None | 1.15A | 5murB-4o87A:undetectable | 5murB-4o87A:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4omj | SEC14-LIKE PROTEIN 2 (Homo sapiens) |
PF00650(CRAL_TRIO) | 4 | TYR A 153ILE A 151ILE A 152ILE A 258 | 2TX A 310 (-4.3A)2TX A 310 ( 4.4A)NoneNone | 0.87A | 5murB-4omjA:undetectable | 5murB-4omjA:14.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pj6 | LEUCYL-CYSTINYLAMINOPEPTIDASE (Homo sapiens) |
PF01433(Peptidase_M1)PF11838(ERAP1_C) | 4 | PRO A 304TYR A 263ILE A 216ILE A 245 | None | 0.89A | 5murB-4pj6A:undetectable | 5murB-4pj6A:7.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qbl | VRR-NUC (Psychrobactersp. PRwf-1) |
PF08774(VRR_NUC) | 4 | TYR A 34ILE A 78ILE A 76ILE A 129 | None | 0.91A | 5murB-4qblA:undetectable | 5murB-4qblA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qwo | PROFILIN (Monkeypox virus) |
PF00235(Profilin) | 4 | PRO A 60ILE A 94ILE A 96ILE A 43 | None | 0.85A | 5murB-4qwoA:undetectable | 5murB-4qwoA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqv | ALGM1 (Sphingomonassp.) |
PF00528(BPD_transp_1) | 4 | TYR A 204ILE A 238ILE A 208ILE A 230 | None | 0.88A | 5murB-4tqvA:2.4 | 5murB-4tqvA:15.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xfs | INTERLEUKIN-18 (Homo sapiens) |
PF00340(IL1) | 4 | PRO A 88ILE A 48THR A 63ILE A 64 | None | 0.94A | 5murB-4xfsA:undetectable | 5murB-4xfsA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 6 | PRO A 120ILE A 208ILE A 209MET A 212THR A 262ILE A 265 | None | 0.78A | 5murB-4yeuA:20.1 | 5murB-4yeuA:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yeu | CYS-LOOPLIGAND-GATED IONCHANNEL,PROTON-GATEDION CHANNEL (Dickeyachrysanthemi;Gloeobacterviolaceus) |
PF02931(Neur_chan_LBD) | 6 | TYR A 204ILE A 208ILE A 209MET A 212THR A 262ILE A 265 | None | 0.78A | 5murB-4yeuA:20.1 | 5murB-4yeuA:13.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yyq | FICIN ISOFORM A (Ficus carica) |
PF00112(Peptidase_C1) | 4 | TYR A 111ILE A 78ILE A 108ILE A 83 | None | 0.93A | 5murB-4yyqA:undetectable | 5murB-4yyqA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zlg | PUTATIVE B-GLYCANPHOSPHORYLASE (Saccharophagusdegradans) |
PF06165(Glyco_transf_36)PF17167(Glyco_hydro_36) | 4 | TYR A 360ILE A 361THR A 366ILE A 365 | None | 0.91A | 5murB-4zlgA:2.7 | 5murB-4zlgA:6.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a4m | HYDROGENASE-1 SMALLCHAIN (Escherichiacoli) |
PF01058(Oxidored_q6)PF14720(NiFe_hyd_SSU_C) | 4 | ILE S 159ILE S 160MET S 163ILE S 72 | None | 0.84A | 5murB-5a4mS:undetectable | 5murB-5a4mS:11.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aff | SYMPORTIN 1 (Chaetomiumthermophilum) |
no annotation | 4 | ILE A 456ILE A 452THR A 476ILE A 480 | None | 0.86A | 5murB-5affA:2.9 | 5murB-5affA:8.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b1r | B-CELLDIFFERENTIATIONANTIGEN CD72 (Mus musculus) |
no annotation | 4 | PRO A 283TYR A 239ILE A 237ILE A 339 | None | 0.92A | 5murB-5b1rA:undetectable | 5murB-5b1rA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b48 | 2-OXOACID--FERREDOXIN OXIDOREDUCTASEALPHA SUBUNIT (Sulfurisphaeratokodaii) |
PF01558(POR)PF01855(POR_N) | 4 | ILE A 187ILE A 190THR A 173ILE A 172 | None | 0.86A | 5murB-5b48A:undetectable | 5murB-5b48A:9.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5djw | ALPHA-GLUCOSIDASE II (Bacteroidesthetaiotaomicron) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2)PF17137(DUF5110) | 4 | PRO A 204TYR A 488ILE A 584ILE A 583 | None | 0.68A | 5murB-5djwA:undetectable | 5murB-5djwA:8.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fku | DNA POLYMERASE IIISUBUNIT ALPHA (Escherichiacoli) |
PF01336(tRNA_anti-codon)PF02811(PHP)PF07733(DNA_pol3_alpha)PF14579(HHH_6) | 5 | PRO A 814TYR A 833ILE A 838ILE A 835ILE A 816 | None | 1.47A | 5murB-5fkuA:2.2 | 5murB-5fkuA:5.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5flz | SPINDLE POLE BODYCOMPONENT SPC98 (Saccharomycescerevisiae) |
PF04130(Spc97_Spc98) | 4 | TYR B 652ILE B 656ILE B 657ILE B 586 | None | 0.88A | 5murB-5flzB:4.0 | 5murB-5flzB:6.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fv0 | ESSC (Geobacillusthermodenitrificans) |
PF01580(FtsK_SpoIIIE) | 4 | TYR A 987ILE A 973ILE A1197ILE A 999 | None | 0.93A | 5murB-5fv0A:undetectable | 5murB-5fv0A:9.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gy0 | GLUCANASE (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9)PF00942(CBM_3) | 4 | TYR A 511ILE A 556ILE A 558ILE A 532 | None | 0.82A | 5murB-5gy0A:undetectable | 5murB-5gy0A:9.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hh9 | PVDN (Pseudomonasaeruginosa) |
PF00266(Aminotran_5) | 4 | TYR A 235ILE A 233ILE A 234ILE A 141 | None | 0.87A | 5murB-5hh9A:undetectable | 5murB-5hh9A:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hjl | TAGATOSE1,6-DIPHOSPHATEALDOLASE (Streptococcusporcinus) |
PF01791(DeoC) | 4 | PRO A 104TYR A 144ILE A 148ILE A 145 | None | 0.84A | 5murB-5hjlA:undetectable | 5murB-5hjlA:13.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ix1 | MORC FAMILY CW-TYPEZINC FINGER PROTEIN3 (Mus musculus) |
PF07496(zf-CW)PF13589(HATPase_c_3) | 5 | ILE A 347ILE A 315MET A 317THR A 370ILE A 371 | None | 1.46A | 5murB-5ix1A:undetectable | 5murB-5ix1A:11.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j8q | CYSTEINE DESULFURASESUFS (Bacillussubtilis) |
PF00266(Aminotran_5) | 4 | ILE A 3ILE A 6MET A 1ILE A 299 | None | 0.91A | 5murB-5j8qA:undetectable | 5murB-5j8qA:12.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbo | BETA-GLUCOSIDASE (Trichodermaharzianum) |
PF00232(Glyco_hydro_1) | 4 | PRO A 173TYR A 270ILE A 214ILE A 274 | None | 0.90A | 5murB-5jboA:undetectable | 5murB-5jboA:8.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5li4 | TAIL SHEATH PROTEIN (Staphylococcusphage 812) |
no annotation | 4 | ILE A 525ILE A 524THR A 517ILE A 518 | None | 0.87A | 5murB-5li4A:undetectable | 5murB-5li4A:11.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mkc | CELL WALL SURFACEANCHOR FAMILYPROTEIN (JO),CELLWALL SURFACE ANCHORFAMILY PROTEIN (IN) (Streptococcuspneumoniae) |
no annotation | 4 | TYR A 204ILE A 193ILE A 206ILE A 715 | None | 0.94A | 5murB-5mkcA:2.7 | 5murB-5mkcA:13.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ol8 | TRANSCRIPTIONELONGATION FACTOR,MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | TYR A 229ILE A 171ILE A 173ILE A 219 | None | 0.87A | 5murB-5ol8A:undetectable | 5murB-5ol8A:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ola | TRANSCRIPTIONELONGATION FACTOR,MITOCHONDRIAL (Homo sapiens) |
no annotation | 4 | TYR A 229ILE A 171ILE A 173ILE A 219 | None | 0.86A | 5murB-5olaA:undetectable | 5murB-5olaA:17.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opg | ENVELOPEGLYCOPROTEIN GN (Hantaanorthohantavirus) |
PF01567(Hanta_G1) | 4 | TYR A 143ILE A 41ILE A 145ILE A 246 | None | 0.91A | 5murB-5opgA:undetectable | 5murB-5opgA:12.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5v6n | PROTON-GATED IONCHANNEL (Gloeobacterviolaceus) |
no annotation | 7 | PRO C 120TYR C 197ILE C 201ILE C 202MET C 205THR C 255ILE C 258 | None | 0.44A | 5murB-5v6nC:36.0 | 5murB-5v6nC:97.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x1x | MUTATOR MUTT PROTEIN (Staphylococcusaureus) |
PF00293(NUDIX) | 4 | PRO A 36ILE A 11ILE A 12ILE A 54 | None | 0.78A | 5murB-5x1xA:undetectable | 5murB-5x1xA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xz3 | PEPTIDOGLYCAN-RECOGNITION PROTEIN (Apis mellifera) |
no annotation | 4 | TYR A 33ILE A 144ILE A 35ILE A 150 | None | 0.65A | 5murB-5xz3A:undetectable | 5murB-5xz3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b7k | ENDO-ALPHA-(1->5)-L-ARABINANASE (Bacilluslicheniformis) |
no annotation | 4 | PRO A 14ILE A 278THR A 25ILE A 37 | None | 0.83A | 5murB-6b7kA:undetectable | 5murB-6b7kA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c8z | ADP-DEPENDENTPHOSPHOFRUCTOKINASE (Methanosarcinales) |
no annotation | 4 | TYR A 256ILE A 291ILE A 246ILE A 299 | None | 0.91A | 5murB-6c8zA:undetectable | 5murB-6c8zA:17.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cud | SHORT TRANSIENTRECEPTOR POTENTIALCHANNEL 3 (Homo sapiens) |
no annotation | 4 | TYR A 774ILE A 771MET A 767ILE A 274 | None | 0.91A | 5murB-6cudA:4.5 | 5murB-6cudA:18.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6evj | RNA-DIRECTED RNAPOLYMERASE CATALYTICSUBUNIT (Influenza Avirus) |
no annotation | 4 | TYR B 555ILE B 552THR B 527ILE B 530 | None | 0.87A | 5murB-6evjB:undetectable | 5murB-6evjB:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g1i | - (-) |
no annotation | 4 | PRO A 222ILE A 168ILE A 169ILE A 267 | NoneNoneNoneOHI A 264 ( 4.0A) | 0.84A | 5murB-6g1iA:undetectable | 5murB-6g1iA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g72 | NADH DEHYDROGENASE[UBIQUINONE]FLAVOPROTEIN 2,MITOCHONDRIAL (Mus musculus) |
no annotation | 4 | TYR E 98ILE E 156ILE E 100ILE E 169 | None | 0.90A | 5murB-6g72E:undetectable | 5murB-6g72E:20.99 |