SIMILAR PATTERNS OF AMINO ACIDS FOR 5MFX_A_ACTA701
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c8m | HUMAN RHINOVIRUS 16COAT PROTEIN (Rhinovirus A) |
PF00073(Rhv) | 4 | ARG 2 103THR 2 43ALA 2 47ASP 2 46 | None | 1.26A | 5mfxA-1c8m2:0.0 | 5mfxA-1c8m2:19.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d7b | CELLOBIOSEDEHYDROGENASE (Phanerochaetechrysosporium) |
PF16010(CDH-cyt) | 4 | THR A 175HIS A 177ALA A 176ASP A 172 | None | 1.39A | 5mfxA-1d7bA:0.0 | 5mfxA-1d7bA:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e5d | RUBREDOXIN:OXYGENOXIDOREDUCTASE (Desulfovibriogigas) |
PF00258(Flavodoxin_1)PF00753(Lactamase_B) | 4 | ARG A 21THR A 33ALA A 172ASP A 17 | None | 1.34A | 5mfxA-1e5dA:2.4 | 5mfxA-1e5dA:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1f4h | BETA-GALACTOSIDASE (Escherichiacoli) |
PF00703(Glyco_hydro_2)PF02836(Glyco_hydro_2_C)PF02837(Glyco_hydro_2_N)PF02929(Bgal_small_N)PF16353(DUF4981) | 4 | THR A 317HIS A 316ALA A 318ASP A 319 | None | 0.94A | 5mfxA-1f4hA:0.0 | 5mfxA-1f4hA:18.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i51 | X-LINKED INHIBITOROF APOPTOSIS PROTEIN (Homo sapiens) |
no annotation | 4 | THR E 135HIS E 136ALA E 137ASP E 138 | None | 1.39A | 5mfxA-1i51E:undetectable | 5mfxA-1i51E:12.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1i9g | HYPOTHETICAL PROTEINRV2118C (Mycobacteriumtuberculosis) |
PF08704(GCD14)PF14801(GCD14_N) | 4 | THR A 252HIS A 251ALA A 253ASP A 87 | None | 1.32A | 5mfxA-1i9gA:2.9 | 5mfxA-1i9gA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jn0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA (Spinaciaoleracea) |
no annotation | 4 | THR O 138HIS O 139ALA O 140ASP O 141 | None | 1.36A | 5mfxA-1jn0O:undetectable | 5mfxA-1jn0O:24.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kr5 | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Homo sapiens) |
PF01135(PCMT) | 4 | ARG A 36HIS A 64ALA A 60ASP A 47 | NoneSAH A 300 (-4.2A)NoneNone | 1.36A | 5mfxA-1kr5A:2.2 | 5mfxA-1kr5A:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1llu | ALCOHOLDEHYDROGENASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 46HIS A 49ALA A 50ASP A 47 | EDO A1260 ( 2.9A)NAD A1250 (-3.9A)NoneNone | 1.31A | 5mfxA-1lluA:2.2 | 5mfxA-1lluA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n2o | PANTOTHENATESYNTHETASE (Mycobacteriumtuberculosis) |
PF02569(Pantoate_ligase) | 4 | ARG A 132THR A 134HIS A 135ALA A 75 | None | 1.33A | 5mfxA-1n2oA:undetectable | 5mfxA-1n2oA:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrk | YGFZ PROTEIN (Escherichiacoli) |
PF01571(GCV_T) | 4 | ARG A 91THR A 31ALA A 110ASP A 112 | None | 1.08A | 5mfxA-1nrkA:undetectable | 5mfxA-1nrkA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o54 | SAM-DEPENDENTO-METHYLTRANSFERASE (Thermotogamaritima) |
PF08704(GCD14) | 4 | THR A 249HIS A 248ALA A 250ASP A 88 | None | 1.32A | 5mfxA-1o54A:3.1 | 5mfxA-1o54A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ovl | ORPHAN NUCLEARRECEPTOR NURR1 (MSE496, 511) (Homo sapiens) |
PF00104(Hormone_recep) | 4 | ARG B 477THR B 400HIS B 402ASP B 398 | None | 1.39A | 5mfxA-1ovlB:undetectable | 5mfxA-1ovlB:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q0z | ACLACINOMYCINMETHYLESTERASE (Streptomycespurpurascens) |
PF00561(Abhydrolase_1) | 4 | ARG A 267THR A 294HIS A 293ALA A 297 | None | 1.45A | 5mfxA-1q0zA:undetectable | 5mfxA-1q0zA:22.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qpa | LIGNIN PEROXIDASE (Phanerochaetechrysosporium) |
PF00141(peroxidase)PF11895(Peroxidase_ext) | 4 | THR A 309HIS A 310ALA A 311ASP A 312 | None | 1.31A | 5mfxA-1qpaA:undetectable | 5mfxA-1qpaA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r18 | PROTEIN-L-ISOASPARTATE(D-ASPARTATE)-O-METHYLTRANSFERASE (Drosophilamelanogaster) |
PF01135(PCMT) | 4 | ARG A 37HIS A 65ALA A 61ASP A 48 | NoneSAH A 300 (-3.9A)NoneNone | 1.38A | 5mfxA-1r18A:2.1 | 5mfxA-1r18A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rjw | ALCOHOLDEHYDROGENASE (Geobacillusstearothermophilus) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 40HIS A 43ALA A 44ASP A 41 | ETF A 501 ( 3.3A)NoneNoneNone | 1.26A | 5mfxA-1rjwA:3.1 | 5mfxA-1rjwA:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w9x | ALPHA AMYLASE (Bacillushalmapalus) |
PF00128(Alpha-amylase)PF09154(DUF1939) | 4 | ARG A 218THR A 251HIS A 252ASP A 248 | None | 1.37A | 5mfxA-1w9xA:undetectable | 5mfxA-1w9xA:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wx4 | TYROSINASE (Streptomycescastaneoglobisporus) |
PF00264(Tyrosinase) | 4 | ARG A 64THR A 266ALA A 267ASP A 264 | NoneNO3 A 408 ( 4.9A)NoneNone | 1.40A | 5mfxA-1wx4A:undetectable | 5mfxA-1wx4A:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ycg | NITRIC OXIDEREDUCTASE (Moorellathermoacetica) |
PF00258(Flavodoxin_1)PF00753(Lactamase_B) | 4 | ARG A 22THR A 35ALA A 174ASP A 18 | None | 1.30A | 5mfxA-1ycgA:undetectable | 5mfxA-1ycgA:23.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zc6 | PROBABLEN-ACETYLGLUCOSAMINEKINASE (Chromobacteriumviolaceum) |
PF01869(BcrAD_BadFG) | 4 | THR A 33HIS A 28ALA A 29ASP A 31 | None | 1.33A | 5mfxA-1zc6A:undetectable | 5mfxA-1zc6A:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zhv | HYPOTHETICAL PROTEINATU0741 (Agrobacteriumfabrum) |
PF13840(ACT_7) | 4 | ARG A 18THR A 40ALA A 21ASP A 42 | None | 1.10A | 5mfxA-1zhvA:undetectable | 5mfxA-1zhvA:15.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b25 | HYPOTHETICAL PROTEIN (Homo sapiens) |
PF08704(GCD14) | 4 | THR A 320HIS A 319ALA A 321ASP A 91 | None | 1.24A | 5mfxA-2b25A:2.0 | 5mfxA-2b25A:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bws | XAA-PROAMINOPEPTIDASE P (Escherichiacoli) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 4 | ARG A 274THR A 196HIS A 195ALA A 192 | None | 1.33A | 5mfxA-2bwsA:2.3 | 5mfxA-2bwsA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ipq | HYPOTHETICAL PROTEINSTY4665 (Salmonellaenterica) |
PF07515(TraI_2_C) | 4 | THR X 422HIS X 428ALA X 423ASP X 424 | None | 1.38A | 5mfxA-2ipqX:undetectable | 5mfxA-2ipqX:14.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j63 | AP-ENDONUCLEASE (Leishmaniamajor) |
PF03372(Exo_endo_phos) | 4 | THR A 310HIS A 328ALA A 309ASP A 306 | None | 1.35A | 5mfxA-2j63A:undetectable | 5mfxA-2j63A:25.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lli | PROTEIN AIR2 (Saccharomycescerevisiae) |
PF00098(zf-CCHC) | 4 | THR A 31HIS A 34ALA A 30ASP A 19 | None ZN A 204 (-3.7A)NoneNone | 1.36A | 5mfxA-2lliA:undetectable | 5mfxA-2lliA:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o36 | THIMETOLIGOPEPTIDASE (Homo sapiens) |
PF01432(Peptidase_M3) | 4 | THR A 274HIS A 275ALA A 276ASP A 277 | None | 1.44A | 5mfxA-2o36A:undetectable | 5mfxA-2o36A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o3e | NEUROLYSIN (Rattusnorvegicus) |
PF01432(Peptidase_M3) | 4 | THR A 275HIS A 276ALA A 277ASP A 278 | None | 1.42A | 5mfxA-2o3eA:undetectable | 5mfxA-2o3eA:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ovi | HYPOTHETICAL PROTEINCHUX (Escherichiacoli) |
PF06228(ChuX_HutX) | 4 | THR A 66HIS A 65ALA A 67ASP A 68 | None | 1.30A | 5mfxA-2oviA:undetectable | 5mfxA-2oviA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pbf | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASEBETA-ASPARTATEMETHYLTRANSFERASE (Plasmodiumfalciparum) |
PF01135(PCMT) | 4 | ARG A 39HIS A 67ALA A 63ASP A 50 | NoneSAH A 301 (-3.9A)NoneNone | 1.42A | 5mfxA-2pbfA:undetectable | 5mfxA-2pbfA:21.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ph0 | UNCHARACTERIZEDPROTEIN (Pectobacteriumcarotovorum) |
PF06228(ChuX_HutX) | 4 | THR A 67HIS A 66ALA A 68ASP A 69 | None | 1.26A | 5mfxA-2ph0A:undetectable | 5mfxA-2ph0A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2plj | LYSINE/ORNITHINEDECARBOXYLASE (Vibriovulnificus) |
PF00278(Orn_DAP_Arg_deC)PF02784(Orn_Arg_deC_N) | 4 | THR A 108HIS A 107ALA A 87ASP A 85 | NoneNoneNoneP3T A 501 ( 4.6A) | 1.16A | 5mfxA-2pljA:undetectable | 5mfxA-2pljA:24.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po3 | 4-DEHYDRASE (Streptomycesvenezuelae) |
PF01041(DegT_DnrJ_EryC1) | 4 | ARG A1222THR A1073HIS A1225ALA A1072 | None | 1.27A | 5mfxA-2po3A:undetectable | 5mfxA-2po3A:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q8h | [PYRUVATEDEHYDROGENASE[LIPOAMIDE]] KINASEISOZYME 1 (Homo sapiens) |
PF02518(HATPase_c)PF10436(BCDHK_Adom3) | 4 | THR A 288HIS A 291ALA A 287ASP A 318 | None | 1.44A | 5mfxA-2q8hA:undetectable | 5mfxA-2q8hA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qez | ETHANOLAMINEAMMONIA-LYASE HEAVYCHAIN (Listeriamonocytogenes) |
PF06751(EutB) | 4 | THR A 230HIS A 227ALA A 226ASP A 197 | None | 1.43A | 5mfxA-2qezA:undetectable | 5mfxA-2qezA:24.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r5v | PCZA361.1 (Amycolatopsisorientalis) |
PF00903(Glyoxalase)PF14696(Glyoxalase_5) | 4 | THR A 125HIS A 124ALA A 79ASP A 77 | None | 1.44A | 5mfxA-2r5vA:undetectable | 5mfxA-2r5vA:22.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vro | ALDEHYDEDEHYDROGENASE (Paraburkholderiaxenovorans) |
PF00171(Aldedh) | 4 | ARG A 431THR A 394HIS A 397ALA A 393 | None | 1.43A | 5mfxA-2vroA:undetectable | 5mfxA-2vroA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vvf | MAJOR CAPSID PROTEINP2 (Pseudoalteromonasvirus PM2) |
no annotation | 4 | ARG A 195THR A 220ALA A 174ASP A 222 | None | 1.25A | 5mfxA-2vvfA:undetectable | 5mfxA-2vvfA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vwb | PUTATIVEO-SIALOGLYCOPROTEINENDOPEPTIDASE (Methanocaldococcusjannaschii) |
PF00814(Peptidase_M22)PF01163(RIO1) | 4 | THR A 9HIS A 48ALA A 10ASP A 284 | NoneNoneANP A1531 ( 4.0A)ANP A1531 (-2.7A) | 1.14A | 5mfxA-2vwbA:undetectable | 5mfxA-2vwbA:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vyc | BIODEGRADATIVEARGININEDECARBOXYLASE (Escherichiacoli) |
PF01276(OKR_DC_1)PF03709(OKR_DC_1_N)PF03711(OKR_DC_1_C) | 4 | THR A 381HIS A 382ALA A 349ASP A 347 | NoneNonePLP A1386 (-3.4A)PLP A1386 (-2.8A) | 1.33A | 5mfxA-2vycA:3.3 | 5mfxA-2vycA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w9m | POLYMERASE X (Deinococcusradiodurans) |
PF14520(HHH_5)PF14716(HHH_8) | 4 | ARG A 189THR A 201ALA A 183ASP A 247 | None | 1.27A | 5mfxA-2w9mA:undetectable | 5mfxA-2w9mA:23.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2waw | MOBA RELATE PROTEIN (Mycobacteriumsp. DSM 3803) |
PF12804(NTP_transf_3) | 4 | ARG A 3THR A 7ALA A 96ASP A 93 | None | 1.06A | 5mfxA-2wawA:undetectable | 5mfxA-2wawA:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xj9 | MIPZ (Caulobactervibrioides) |
PF09140(MipZ) | 4 | THR A 27HIS A 24ALA A 235ASP A 236 | None | 1.30A | 5mfxA-2xj9A:3.0 | 5mfxA-2xj9A:19.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yt0 | AMYLOID BETA A4PROTEIN AND AMYLOIDBETA A4 PRECURSORPROTEIN-BINDINGFAMILY B MEMBER 2 (Mus musculus) |
PF00640(PID)PF10515(APP_amyloid) | 4 | ARG A 129THR A 110ALA A 109ASP A 108 | None | 1.41A | 5mfxA-2yt0A:undetectable | 5mfxA-2yt0A:14.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvl | HYPOTHETICAL PROTEIN (Aquifexaeolicus) |
PF08704(GCD14) | 4 | THR A 237HIS A 236ALA A 238ASP A 79 | None | 1.33A | 5mfxA-2yvlA:2.6 | 5mfxA-2yvlA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zu6 | EUKARYOTICINITIATION FACTOR4A-I (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ARG A 334THR A 329ALA A 333ASP A 330 | None | 1.44A | 5mfxA-2zu6A:9.7 | 5mfxA-2zu6A:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a3j | PBP5 (Haemophilusinfluenzae) |
PF00768(Peptidase_S11)PF07943(PBP5_C) | 4 | THR A 235HIS A 234ALA A 64ASP A 172 | NoneSO4 A 1 (-3.7A)NoneNone | 1.16A | 5mfxA-3a3jA:undetectable | 5mfxA-3a3jA:20.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8o | LIPOPOLYSACCHARIDEBIOSYNTHESIS PROTEINWZZE (Escherichiacoli) |
no annotation | 4 | ARG A 128THR A 168ALA A 166ASP A 171 | None | 1.33A | 5mfxA-3b8oA:undetectable | 5mfxA-3b8oA:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3c10 | HISTONE DEACETYLASE7A (Homo sapiens) |
PF00850(Hist_deacetyl) | 4 | THR A 675HIS A 585ALA A 671ASP A 672 | None | 1.36A | 5mfxA-3c10A:3.1 | 5mfxA-3c10A:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dc7 | PUTATIVEUNCHARACTERIZEDPROTEIN LP_3323 (Lactobacillusplantarum) |
PF13472(Lipase_GDSL_2) | 4 | THR A 32HIS A 41ALA A 33ASP A 29 | None | 1.10A | 5mfxA-3dc7A:undetectable | 5mfxA-3dc7A:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iup | PUTATIVENADPH:QUINONEOXIDOREDUCTASE (Cupriaviduspinatubonensis) |
no annotation | 4 | THR A 177HIS A 176ALA A 178ASP A 245 | NoneNoneNDP A 401 ( 3.8A)None | 1.44A | 5mfxA-3iupA:3.8 | 5mfxA-3iupA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iup | PUTATIVENADPH:QUINONEOXIDOREDUCTASE (Cupriaviduspinatubonensis) |
no annotation | 4 | THR A 177HIS A 176ALA A 246ASP A 245 | NoneNoneNDP A 401 ( 3.8A)None | 1.27A | 5mfxA-3iupA:3.8 | 5mfxA-3iupA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbz | SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08771(FRB_dom) | 4 | THR A1984HIS A1988ALA A1986ASP A1947 | None | 1.13A | 5mfxA-3jbzA:undetectable | 5mfxA-3jbzA:16.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jr2 | HEXULOSE-6-PHOSPHATESYNTHASE SGBH (Vibrio cholerae) |
PF00215(OMPdecase) | 4 | THR A 94HIS A 91ALA A 90ASP A 67 | SO4 A 501 (-2.9A)NoneNoneSO4 A 501 (-4.4A) | 1.42A | 5mfxA-3jr2A:undetectable | 5mfxA-3jr2A:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lm3 | UNCHARACTERIZEDPROTEIN (Parabacteroidesdistasonis) |
PF12979(DUF3863)PF12980(DUF3864) | 4 | THR A 59HIS A 79ALA A 108ASP A 111 | None | 1.37A | 5mfxA-3lm3A:2.3 | 5mfxA-3lm3A:21.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m8u | HEME-BINDING PROTEINA (Glaesserellaparasuis) |
PF00496(SBP_bac_5) | 4 | ARG A 249THR A 247ALA A 248ASP A 245 | None | 1.32A | 5mfxA-3m8uA:undetectable | 5mfxA-3m8uA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mkv | PUTATIVEAMIDOHYDROLASE (unidentified) |
PF01979(Amidohydro_1) | 4 | ARG A 262THR A 260ALA A 261ASP A 257 | None | 1.33A | 5mfxA-3mkvA:undetectable | 5mfxA-3mkvA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o04 | BETA-KETO-ACYLCARRIER PROTEINSYNTHASE II (Listeriamonocytogenes) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C) | 4 | THR A 217HIS A 367ALA A 218ASP A 214 | None | 1.25A | 5mfxA-3o04A:undetectable | 5mfxA-3o04A:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oes | GTPASE RHEBL1 (Homo sapiens) |
PF00071(Ras) | 4 | THR A 20HIS A 24ALA A 23ASP A 60 | MG A 202 ( 3.2A)NoneNone MG A 202 ( 3.7A) | 1.25A | 5mfxA-3oesA:3.0 | 5mfxA-3oesA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qxz | ENOYL-COAHYDRATASE/ISOMERASE (Mycobacteroidesabscessus) |
PF00378(ECH_1) | 4 | THR A 111HIS A 115ALA A 142ASP A 139 | NoneNoneNoneEDO A 264 (-4.1A) | 1.04A | 5mfxA-3qxzA:undetectable | 5mfxA-3qxzA:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9u | THIOREDOXINREDUCTASE (Campylobacterjejuni) |
PF07992(Pyr_redox_2) | 4 | ARG A 176THR A 199HIS A 174ASP A 177 | None | 1.24A | 5mfxA-3r9uA:undetectable | 5mfxA-3r9uA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rr6 | PUTATIVEUNCHARACTERIZEDPROTEIN (Mycobacteroidesabscessus) |
PF01557(FAA_hydrolase)PF10370(DUF2437) | 4 | ARG A 160HIS A 164ALA A 148ASP A 150 | EDO A 265 (-4.0A)EDO A 265 (-4.8A)NoneNone | 1.35A | 5mfxA-3rr6A:undetectable | 5mfxA-3rr6A:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s6p | CAPSID PROTEIN (Helicoverpaarmigera stuntvirus) |
PF03566(Peptidase_A21) | 4 | ARG A 421THR A 288HIS A 287ALA A 305 | None | 1.31A | 5mfxA-3s6pA:undetectable | 5mfxA-3s6pA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sok | FIMBRIAL PROTEIN (Dichelobacternodosus) |
PF00114(Pilin)PF07963(N_methyl) | 4 | ARG A 46THR A 79ALA A 78ASP A 70 | None | 1.17A | 5mfxA-3sokA:undetectable | 5mfxA-3sokA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uko | ALCOHOLDEHYDROGENASECLASS-3 (Arabidopsisthaliana) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 166HIS A 90ALA A 167ASP A 164 | None | 1.35A | 5mfxA-3ukoA:2.7 | 5mfxA-3ukoA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3woy | CLIP-ASSOCIATINGPROTEIN 2 (Homo sapiens) |
PF12348(CLASP_N) | 4 | ARG A 154THR A 195ALA A 199ASP A 66 | None | 1.31A | 5mfxA-3woyA:undetectable | 5mfxA-3woyA:21.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zig | SEPF-LIKE PROTEIN (Pyrococcusfuriosus) |
PF04472(SepF) | 4 | THR A 60HIS A 61ALA A 62ASP A 63 | None | 1.33A | 5mfxA-3zigA:undetectable | 5mfxA-3zigA:12.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zs6 | PERIPLASMICOLIGOPEPTIDE-BINDINGPROTEIN (Burkholderiapseudomallei) |
PF00496(SBP_bac_5) | 4 | THR A 110HIS A 105ALA A 107ASP A 109 | None | 1.29A | 5mfxA-3zs6A:undetectable | 5mfxA-3zs6A:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zz1 | BETA-D-GLUCOSIDEGLUCOHYDROLASE (Trichodermareesei) |
PF00933(Glyco_hydro_3)PF01915(Glyco_hydro_3_C)PF14310(Fn3-like) | 4 | THR A 436HIS A 481ALA A 355ASP A 374 | None | 1.39A | 5mfxA-3zz1A:2.1 | 5mfxA-3zz1A:20.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bkw | ZINC FINGER FYVEDOMAIN-CONTAININGPROTEIN 9 (Homo sapiens) |
PF11979(DUF3480) | 4 | THR A1198HIS A1172ALA A1169ASP A1170 | EDO A2370 (-4.2A)NoneNoneNone | 1.26A | 5mfxA-4bkwA:undetectable | 5mfxA-4bkwA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4coy | EPITHELIAL ADHESIN 6 ([Candida]glabrata) |
PF10528(GLEYA) | 4 | THR A 154HIS A 157ALA A 213ASP A 212 | None | 1.33A | 5mfxA-4coyA:undetectable | 5mfxA-4coyA:18.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cxk | ARYLSULFATASE (Pseudomonasaeruginosa) |
PF00884(Sulfatase) | 4 | ARG A 469THR A 406HIS A 46ALA A 405 | None | 1.44A | 5mfxA-4cxkA:2.1 | 5mfxA-4cxkA:22.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dzi | PUTATIVE TIM-BARRELMETAL-DEPENDENTHYDROLASE (Mycobacteriumavium) |
PF04909(Amidohydro_2) | 4 | ARG A 205HIS A 212ALA A 171ASP A 172 | None | 1.44A | 5mfxA-4dziA:undetectable | 5mfxA-4dziA:23.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6c | AUSA REDUCTASEDOMAIN PROTEIN (Staphylococcusaureus) |
PF07993(NAD_binding_4) | 4 | ARG A2228HIS A2298ALA A2191ASP A2192 | None | 1.35A | 5mfxA-4f6cA:undetectable | 5mfxA-4f6cA:22.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f6l | AUSA REDUCTASEDOMAIN PROTEIN (Staphylococcusaureus) |
no annotation | 4 | ARG B2228HIS B2298ALA B2191ASP B2192 | None | 1.41A | 5mfxA-4f6lB:undetectable | 5mfxA-4f6lB:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ghk | GAMMA-GLUTAMYLPHOSPHATE REDUCTASE (Burkholderiathailandensis) |
PF00171(Aldedh) | 4 | ARG A 148THR A 183ALA A 184ASP A 185 | None | 1.45A | 5mfxA-4ghkA:3.0 | 5mfxA-4ghkA:23.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hvm | TLMII (Streptoalloteichushindustanus) |
PF00668(Condensation) | 4 | ARG A 296THR A 412ALA A 351ASP A 410 | None | 1.32A | 5mfxA-4hvmA:undetectable | 5mfxA-4hvmA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4izg | MANDELATERACEMASE/MUCONATELACTONIZING ENZYME,N-TERMINAL DOMAINPROTEIN (Paracoccusdenitrificans) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | ARG A 119THR A 306HIS A 307ALA A 310 | None | 1.30A | 5mfxA-4izgA:undetectable | 5mfxA-4izgA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ks9 | MALONYL-COADECARBOXYLASE (Cupriavidusmetallidurans) |
PF05292(MCD)PF17408(MCD_N) | 4 | ARG A 398THR A 390HIS A 394ALA A 393 | None | 1.26A | 5mfxA-4ks9A:undetectable | 5mfxA-4ks9A:20.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mru | SUSD HOMOLOG (Bacteroidesthetaiotaomicron) |
PF12741(SusD-like) | 4 | ARG A 337THR A 340ALA A 272ASP A 343 | None | 1.29A | 5mfxA-4mruA:undetectable | 5mfxA-4mruA:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oer | NIKA PROTEIN (Brucella suis) |
PF00496(SBP_bac_5) | 4 | ARG A 445THR A 443ALA A 444ASP A 441 | GOL A 606 ( 4.4A)NoneNoneNone | 1.30A | 5mfxA-4oerA:undetectable | 5mfxA-4oerA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pv4 | PROLINEAMINOPEPTIDASE P II (Yersinia pestis) |
PF00557(Peptidase_M24)PF05195(AMP_N) | 4 | ARG A 272THR A 194HIS A 193ALA A 190 | None | 1.32A | 5mfxA-4pv4A:undetectable | 5mfxA-4pv4A:20.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4s28 | PHOSPHOMETHYLPYRIMIDINE SYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF01964(ThiC_Rad_SAM) | 4 | THR A 486HIS A 464ALA A 501ASP A 498 | None | 1.35A | 5mfxA-4s28A:undetectable | 5mfxA-4s28A:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uww | STRUTHIOCALCIN-1 (Struthiocamelus) |
PF00059(Lectin_C) | 4 | ARG A 35THR A 131ALA A 132ASP A 1 | None | 1.14A | 5mfxA-4uwwA:undetectable | 5mfxA-4uwwA:13.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w6z | ALCOHOLDEHYDROGENASE 1 (Saccharomycescerevisiae) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | THR A 45HIS A 48ALA A 49ASP A 46 | ETF A 404 (-2.6A)8ID A 403 (-4.0A)NoneNone | 1.30A | 5mfxA-4w6zA:undetectable | 5mfxA-4w6zA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wjs | RSA4 (Chaetomiumthermophilum) |
PF00400(WD40) | 4 | ARG A 263THR A 211HIS A 231ALA A 232 | None | 1.42A | 5mfxA-4wjsA:undetectable | 5mfxA-4wjsA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wq5 | TRNATHREONYLCARBAMOYLADENOSINE BIOSYNTHESISPROTEIN TSAB (Escherichiacoli) |
PF00814(Peptidase_M22) | 4 | THR C 10HIS C 34ALA C 12ASP C 7 | NoneACT C 301 (-4.6A)NoneNone | 1.30A | 5mfxA-4wq5C:undetectable | 5mfxA-4wq5C:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x00 | PUTATIVE HYDROLASE (Burkholderiacenocepacia) |
PF12697(Abhydrolase_6) | 4 | THR A 164HIS A 165ALA A 159ASP A 161 | None | 1.32A | 5mfxA-4x00A:undetectable | 5mfxA-4x00A:24.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xax | CARD (Thermusthermophilus) |
PF02559(CarD_CdnL_TRCF) | 4 | THR B 93HIS B 90ALA B 128ASP B 125 | None | 1.42A | 5mfxA-4xaxB:undetectable | 5mfxA-4xaxB:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cju | ISOBUTYRYL-COAMUTASE FUSED (Cupriavidusmetallidurans) |
PF01642(MM_CoA_mutase)PF02310(B12-binding)PF03308(ArgK) | 4 | ARG A 232THR A 394ALA A 396ASP A 401 | NoneNoneGDP A1104 (-3.8A)None | 1.37A | 5mfxA-5cjuA:2.1 | 5mfxA-5cjuA:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cqf | L-LYSINE6-MONOOXYGENASE (Pseudomonassyringae groupgenomosp. 3) |
PF13434(K_oxygenase) | 4 | THR A 319HIS A 318ALA A 320ASP A 321 | None | 1.18A | 5mfxA-5cqfA:2.6 | 5mfxA-5cqfA:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dld | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Burkholderiavietnamiensis) |
PF02350(Epimerase_2) | 4 | ARG A 283THR A 205ALA A 206ASP A 203 | None | 1.14A | 5mfxA-5dldA:2.6 | 5mfxA-5dldA:24.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e7p | CELL DIVISIONCONTROL PROTEINCDC48 (Mycolicibacteriumsmegmatis) |
PF00004(AAA)PF02359(CDC48_N) | 4 | ARG A 397THR A 395ALA A 396ASP A 393 | None | 1.36A | 5mfxA-5e7pA:4.6 | 5mfxA-5e7pA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h05 | AMYP (marinemetagenome) |
PF00128(Alpha-amylase) | 4 | ARG A 100THR A 34HIS A 32ASP A 82 | None | 1.45A | 5mfxA-5h05A:undetectable | 5mfxA-5h05A:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hwq | HYDROXYMETHYLGLUTARYL-COA SYNTHASE (Myxococcusxanthus) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 4 | THR A 312HIS A 250ALA A 313ASP A 145 | CSO A 115 ( 3.9A)CSO A 115 (-3.5A)NoneNone | 1.30A | 5mfxA-5hwqA:undetectable | 5mfxA-5hwqA:23.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jmv | PROBABLEBIFUNCTIONAL TRNATHREONYLCARBAMOYLADENOSINE BIOSYNTHESISPROTEIN (Methanocaldococcusjannaschii) |
PF00814(Peptidase_M22) | 4 | THR A 9HIS A 48ALA A 10ASP A 284 | NoneNoneNone MG A 402 ( 2.7A) | 1.15A | 5mfxA-5jmvA:undetectable | 5mfxA-5jmvA:22.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t4y | SUSC HOMOLOG (Bacteroidesthetaiotaomicron) |
no annotation | 4 | THR D 800HIS D 799ALA D 803ASP D 854 | None | 0.97A | 5mfxA-5t4yD:undetectable | 5mfxA-5t4yD:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5te1 | ATP-CITRATE SYNTHASE (Homo sapiens) |
PF00549(Ligase_CoA)PF02629(CoA_binding)PF16114(Citrate_bind) | 4 | ARG A 662HIS A 760ALA A 761ASP A 690 | NonePO4 A 902 (-3.9A)NoneNone | 1.29A | 5mfxA-5te1A:undetectable | 5mfxA-5te1A:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6r | GENOME POLYPROTEIN (Pestivirus C) |
no annotation | 4 | ARG A 517THR A 520ALA A 524ASP A 268 | SO4 A 720 (-3.1A)NoneNoneNone | 1.11A | 5mfxA-5y6rA:undetectable | 5mfxA-5y6rA:undetectable |